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SG11201407340YA - Treatment of myelosuppression - Google Patents

Treatment of myelosuppression

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Publication number
SG11201407340YA
SG11201407340YASG11201407340YASG11201407340YASG11201407340YASG 11201407340Y ASG11201407340Y ASG 11201407340YASG 11201407340Y ASG11201407340Y ASG 11201407340YASG 11201407340Y ASG11201407340Y ASG 11201407340YASG 11201407340Y ASG11201407340Y ASG 11201407340YA
Authority
SG
Singapore
Prior art keywords
patient
day
cycle
international
control arm
Prior art date
Application number
SG11201407340YA
Inventor
Stephen Marcus
Original Assignee
Cantex Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cantex Pharmaceuticals IncfiledCriticalCantex Pharmaceuticals Inc
Publication of SG11201407340YApublicationCriticalpatent/SG11201407340YA/en

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Abstract

(12) INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 14 November 2013 (14.11.2013) WIPOIPCT (10) International Publication Number WO 2013/169355 A1 (51) International Patent Classification: A61K 31/727 (2006.01) C08B 37/10 (2006.01) A61K31/715 (2006.01) (21) International Application Number: PCT/US2013/031053 13 March 2013 (13.03.2013) English English (22) International Filing Date: (25) Filing Language: (26) Publication Language: (30) Priority Data: 61/644,623 61/644,556 61/648,043 61/653,362 61/664,611 61/668,709 61/678,053 61/702,207 61/724,836 1792 Bell Tower Lane, Weston, FL 33326 (US). (72) Inventor: MARCUS, Stephen; Suite 222, 1792 Bell Tower Lane, Weston, FL 33326 (US). 9 May 2012 (09.05.2012) US 9 May 2012 (09.05.2012) us 16 May 2012 (16.05.2012) us 30 May 2012 (30.05.2012) us 26 June 2012 (26.06.2012) us 6 July 2012 (06.07.2012) us 31 July 2012 (31.07.2012) us 17 September 2012 (17.09.2012) us 9 November 2012 (09.11.2012) us PARINGENIX, INC. [US/US]; Suite 222, (74) Agents: BECKER, Daniel et al.; Dechert LLP, P.O. Box 390460, Mountain View, CA 94039 (US). (81) Designated States (unless otherwise indicated, for every kind of national protection available)'. AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available)'. ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG). Published: — with international search report (Art. 21(3)) (54) Title: TREATMENT OF MYELOSUPPRESSION FIG. 13A Platelet count 10 /nl (X 3 blood) o\ Control Arm Patients ODSH Arm Patients ~Z3C 231- Patient 6008 Patient 9003 Patient 1X002 Patient 14005 Patient 14003 Patient 9004 Patient 6009 Patient 14002 Patient 14001 Patient 9002 • Cycle 1 Day 1 • Cycle 1 Day 15 Cycle 1 Day 1 Cycle 1 Day 15 Control Arm Median 194 92 Control Arm Mean 193 88 Cycle 1 Day 1 Cycle 1 Day 15 ODSH Arm Median 194 199 ODSH Arm Mean 219 177 T-H o CJ (57) Abstract: Methods are presented for attenuating myelosuppressive side effects of treatment regimens, promoting thrombopoies- is and neutrophil production, and increasing efficacy of treatment regimens, by administering PF4-interacting heparinoids.
SG11201407340YA2012-05-092013-03-13Treatment of myelosuppressionSG11201407340YA (en)

Applications Claiming Priority (10)

Application NumberPriority DateFiling DateTitle
US201261644556P2012-05-092012-05-09
US201261644623P2012-05-092012-05-09
US201261648043P2012-05-162012-05-16
US201261653362P2012-05-302012-05-30
US201261664611P2012-06-262012-06-26
US201261668709P2012-07-062012-07-06
US201261678053P2012-07-312012-07-31
US201261702207P2012-09-172012-09-17
US201261724836P2012-11-092012-11-09
PCT/US2013/031053WO2013169355A1 (en)2012-05-092013-03-13Treatment of myelosuppression

Publications (1)

Publication NumberPublication Date
SG11201407340YAtrue SG11201407340YA (en)2014-12-30

Family

ID=49549076

Family Applications (3)

Application NumberTitlePriority DateFiling Date
SG10201603059YASG10201603059YA (en)2012-05-092013-03-13Treatment Of Myelosuppression
SG11201407340YASG11201407340YA (en)2012-05-092013-03-13Treatment of myelosuppression
SG10201914117QASG10201914117QA (en)2012-05-092013-03-13Treatment Of Myelosuppression

Family Applications Before (1)

Application NumberTitlePriority DateFiling Date
SG10201603059YASG10201603059YA (en)2012-05-092013-03-13Treatment Of Myelosuppression

Family Applications After (1)

Application NumberTitlePriority DateFiling Date
SG10201914117QASG10201914117QA (en)2012-05-092013-03-13Treatment Of Myelosuppression

Country Status (20)

CountryLink
US (6)US9271999B2 (en)
EP (2)EP2846809B1 (en)
JP (3)JP6177885B2 (en)
KR (2)KR102452803B1 (en)
CN (3)CN108498532B (en)
AU (1)AU2013260101B2 (en)
BR (1)BR112014028094B1 (en)
CA (2)CA3122808A1 (en)
CL (2)CL2014003017A1 (en)
DK (1)DK2846809T3 (en)
EA (1)EA029382B1 (en)
ES (1)ES2848050T3 (en)
HU (1)HUE053247T2 (en)
IL (1)IL235593B (en)
LT (1)LT2846809T (en)
MX (2)MX370567B (en)
PL (1)PL2846809T3 (en)
PT (1)PT2846809T (en)
SG (3)SG10201603059YA (en)
WO (1)WO2013169355A1 (en)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication numberPriority datePublication dateAssigneeTitle
CN108498532B (en)2012-05-092021-07-23坎泰克斯制药股份有限公司Treatment of myelosuppression
CN105848672A (en)*2013-10-222016-08-10坎泰克斯制药股份有限公司Methods of treating and preventing radiation damage
WO2015142924A1 (en)2014-03-172015-09-24Cantex Pharmaceuticals, Inc.Multivalent cation formulations of partially desulfated heparins
EP3258941A4 (en)2015-02-172018-09-26Cantex Pharmaceuticals, Inc.Treatment of cancers and hematopoietic stem cell disorders privileged by cxcl12-cxcr4 interaction
SG11201707127VA (en)2015-03-062017-09-28Beyondspring Pharmaceuticals IncMethod of treating cancer associated with a ras mutation
SG10202108194XA (en)2015-07-132021-09-29Beyondspring Pharmaceuticals IncPlinabulin compositions
RU2753543C1 (en)2016-02-082021-08-17Бейондспринг Фармасьютикалс, Инк.Compositions containing tucaresol or analogues thereof
CN118304304A (en)2016-06-062024-07-09大连万春布林医药有限公司Compositions and methods for reducing neutropenia
EP3565812B1 (en)2017-01-062023-12-27Beyondspring Pharmaceuticals, Inc.Tubulin binding compounds and therapeutic use thereof
CN110381938A (en)2017-02-012019-10-25大连万春布林医药有限公司The method for reducing neutrophil leucocyte deficiency disease
CN107569486A (en)*2017-08-232018-01-12北京京佑奇康生物科技有限公司Menglusitena treats the new application of thrombopenia
GB2571696B (en)2017-10-092020-05-27Compass Pathways LtdLarge scale method for the preparation of Psilocybin and formulations of Psilocybin so produced
US11786523B2 (en)2018-01-242023-10-17Beyondspring Pharmaceuticals, Inc.Composition and method for reducing thrombocytopenia
US11874276B2 (en)2018-04-052024-01-16Dana-Farber Cancer Institute, Inc.STING levels as a biomarker for cancer immunotherapy
WO2022015794A1 (en)2020-07-142022-01-20Optimvia, LlcMethods for synthesizing non-anticoagulant heparan sulfate
CA3127458A1 (en)*2019-01-252020-07-30Janssen Pharmaceutica NvMethods of enhancing protection against organ and vascular injury, hematopoietic recovery and survival in response to total body radiation/chemical exposure
CA3138100A1 (en)2019-04-172020-10-22Compass Pathfinder LimitedTreatment of depression and other various disorders with psilocybin
WO2021041532A1 (en)*2019-08-262021-03-04Dana-Farber Cancer Institute, Inc.Use of heparin to promote type 1 interferon signaling
PH12022551169A1 (en)*2019-11-132024-02-19Astex Pharmaceuticals IncMETHODS OF TREATING LSD1-RELATED DISEASES and Disorders WITH LSD1 INHIBITORS
WO2021207697A1 (en)2020-04-102021-10-14Cantex Pharmaceuticals, Inc.Treatment of acute lung injury
US20240197723A1 (en)2021-04-092024-06-20Beyondspring Pharmaceuticals, Inc.Therapeutic compositions and methods for treating tumors
KR102856472B1 (en)2021-10-212025-09-11숙명여자대학교산학협력단Combination therapy with griseofulvin for blood cancer
CN116212020B (en)*2022-12-092025-05-30中国医学科学院放射医学研究所Application of JAK inhibitor in medicine for preventing and treating radiation-induced bone marrow suppression and intestinal injury
CN116983325A (en)*2023-08-182023-11-03首都儿科研究所Use of co-active ingredients for the preparation of a medicament for the treatment of tumors

Family Cites Families (81)

* Cited by examiner, † Cited by third party
Publication numberPriority datePublication dateAssigneeTitle
FR2374910A1 (en)1976-10-231978-07-21Choay Sa PREPARATION BASED ON HEPARIN, INCLUDING LIPOSOMES, PROCESS FOR OBTAINING IT AND MEDICINAL PRODUCTS CONTAINING SUCH PREPARATIONS
US5804374A (en)1980-12-051998-09-08Massachusetts Insti. TechnologyNuclear factors associates with transcriptional regulation
FR2553287B1 (en)1983-10-181986-09-12Choay Sa COMPOSITIONS BASED ON MUCOPOLYSACCHARIDES OR OLIGOSACCHARIDES, ESPECIALLY BASED ON HEPARIN FRACTIONS OR FRAGMENTS, SUITABLE FOR THE TREATMENT OF CELL PROLIFERATION DISORDERS
DE3422518A1 (en)1984-06-161985-12-19B. Braun Melsungen Ag, 3508 Melsungen HEPARIN DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, MEDICINAL PRODUCTS CONTAINING THEM AND THEIR USE IN THE TREATMENT OF FATTY METABOLISM DISORDERS
FR2584606A1 (en)1985-07-121987-01-16Dropic USE OF POLY- AND OLIGOSACCHARIDES FOR THE PRODUCTION OF ACTIVE MEDICAMENTS IN THE PATHOLOGIES OF CONNECTIVE TISSUE
US5380716A (en)1988-12-151995-01-10Glycomed, Inc.Sulfated polysaccharides as inhibitors of smooth muscle cell proliferation
IT1234826B (en)1989-01-301992-05-29Alfa Wassermann Spa HEPARIN DERIVATIVES AND PROCEDURE FOR THEIR PREPARATION
US5399493A (en)1989-06-151995-03-21The Regents Of The University Of MichiganMethods and compositions for the optimization of human hematopoietic progenitor cell cultures
WO1991015216A1 (en)1990-04-051991-10-17Kennedy Thomas PMethod and medicament for prevention or medication of human leucocyte elastase-mediated pulmonary diseases
US5250519A (en)1991-03-291993-10-05Glycomed IncorporatedNon-anticoagulant heparin derivatives
IT1254216B (en)1992-02-251995-09-14Opocrin Spa POLYSACCHARIDIC DERIVATIVES OF HEPARIN, EPARAN SULPHATE, THEIR FRACTIONS AND FRAGMENTS, PROCEDURE FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
WO1993019734A1 (en)1992-04-021993-10-14Baker Norton Pharmaceuticals, Inc.Method and composition for treating antigen-induced and exercise-induced asthma
US5668118A (en)1992-07-241997-09-16Cavalier PharmaceuticalsMethod of synthesis of 2-O-desulfated Heparin and use thereof for inhibition of elastase and Cathepspin G
US5306724A (en)1992-08-171994-04-26Clintec Nutrition CompanyMethod for preventing and treating atherosclerosis
GB2270841A (en)1992-09-091994-03-30Merck & Co IncCompositions for Treating vascular restenosis
US5696100A (en)*1992-12-221997-12-09Glycomed IncorporatedMethod for controlling O-desulfation of heparin and compositions produced thereby
US5296471A (en)1992-12-221994-03-22Glycomed IncorporatedMethod for controlling o-desulfation of heparin and compositions produced thereby
AU6246394A (en)1993-02-221994-09-14Cavalier Pharmaceuticals, Inc.Use of heparin to inhibit interleukin-8
SE9302135D0 (en)1993-06-181993-06-18Kabi Pharmacia Ab NEW PHARMACEUTICAL COMPOSITION
US5994318A (en)1993-10-041999-11-30Albany Medical CollegeCochleate delivery vehicles
US5840707A (en)1993-10-041998-11-24Albany Medical CollegeStabilizing and delivery means of biological molecules
EP0758247A4 (en)1994-05-061997-08-20Glycomed IncO-desulfated heparin derivatives, methods of making and uses thereof
US5804560A (en)1995-01-061998-09-08Sibia Neurosciences, Inc.Peptide and peptide analog protease inhibitors
JP4097044B2 (en)1996-07-292008-06-04パリンジェニックス,インコーポレイテッド How to treat asthma with O-desulfated heparin
US6154502A (en)1996-08-222000-11-28Intel CorporationSignal constellation slicer
US7258857B2 (en)1996-11-222007-08-21The Trustees Of Columbia University In The City Of New YorkRage-related methods for treating inflammation
NZ337364A (en)1997-02-152001-06-29Millennium Pharm IncTreatment of infarcts, ischemia and reperfusion through inhibition of NFkappaB
AU8657098A (en)1997-05-301998-12-30Arch Development CorporationP-selectin translocation to vascular epithelial lumen by ionizing radiation
US6406862B1 (en)1998-10-062002-06-18The United States Of America As Represented By The Secretary Of The ArmyDip-stick assay for C-reactive protein
CN1326355A (en)1998-11-132001-12-12伊莱利利公司Method of treating heparin-induced thrombocytopenia
US20030083231A1 (en)*1998-11-242003-05-01Ahlem Clarence N.Blood cell deficiency treatment method
US6153217A (en)1999-01-222000-11-28Biodelivery Sciences, Inc.Nanocochleate formulations, process of preparation and method of delivery of pharmaceutical agents
US6514502B1 (en)1999-01-262003-02-04Schering-Plough Veterinary CorporationPropagation of bovine cononavirus in chinese hamster ovary cells
EP1223948A2 (en)1999-09-132002-07-24CHARLOTTE-MECKLENBURG HOSPITAL doing business as Carolinas Medical CenterMethod of inhibiting nf-kappa-b with heparin, for treating cardiovascular diseases and inflammations
US7781416B2 (en)2000-01-252010-08-24Sigma-Tau Research Switzerland S.A.Derivatives of partially desulphated glycosaminoglycans as heparanase inhibitors, endowed with antiangiogenic activity and devoid of anticoagulating effect
US6489311B1 (en)2000-05-022002-12-03Charlotte-Mecklenburg Hospital AuthoirtyMethod for the prevention of apoptosis
MXPA03009436A (en)*2001-04-182004-12-06Prometic Biosciences IncMedium-chain length fatty acids, glycerides and analogues as neutrophil survival and activation factors.
US20040072796A1 (en)2002-04-182004-04-15Embury Stephen H.Method and composition for preventing pain in sickle cell patients
EP1523310A2 (en)2002-07-092005-04-20The Scripps Research InstituteMethod to inhibit ischemia and reperfusion injury
US8404716B2 (en)2002-10-152013-03-26Celgene CorporationMethods of treating myelodysplastic syndromes with a combination therapy using lenalidomide and azacitidine
AU2003293122A1 (en)2002-11-272004-06-23Massachusetts Institute Of TechnologyMethods for synthesizing polysaccharides
US20040180812A1 (en)*2002-12-132004-09-16Technology CenterMethods of treating and preventing proliferative disease
WO2005000295A1 (en)2003-05-202005-01-06Transtech Pharma, Inc.Rage antagonists as agents to reverse amyloidosis and diseases associated therewith
US7538096B2 (en)2004-03-162009-05-26The General Hospital CorporationTreatment and prevention of abnormal cellular proliferation
EP1744764B1 (en)*2004-04-222012-05-30Celator Pharmaceuticals, Inc.Liposomal formulations of anthracycline agents and cytidine analogs
US20050261241A1 (en)2004-05-192005-11-24Celsus Biopharmaceuticals, Inc.Use of dermatan sulfates and/or desulfated heparins to treat or prevent heparinoid-induced autoimmune responses
US20050282775A1 (en)2004-06-162005-12-22Paringenix, Inc.Method and medicament for sulfated polysaccharide treatment of inflammation without inducing platelet activation and heparin-induced thrombocytopenia syndrome
US7468358B2 (en)2004-06-162008-12-23Paringenix, Inc.Method and medicament for sulfated polysaccharide treatment of heparin-induced thrombocytopenia (HIT) syndrome
US20060040896A1 (en)2004-08-182006-02-23Paringenix, Inc.Method and medicament for anticoagulation using a sulfated polysaccharide with enhanced anti-inflammatory activity
JP2006076968A (en)2004-09-102006-03-23Seikagaku Kogyo Co LtdPhysiologically active molecule-containing crosslinked heparin gel composition
CA2616166A1 (en)2005-07-222007-02-01The Regents Of The University Of CaliforniaHeparin compositions and selectin inhibition
WO2007019554A2 (en)2005-08-082007-02-15Momenta Pharmaceuticals, Inc.Polysaccharides for delivery of active agents
CA2623735A1 (en)2005-09-302007-04-12Takara Bio Inc.Method for production of t cell population
CN101336253A (en)2005-12-162008-12-31Dnp加拿大公司Chitin derivatives for hyperlipidemia
WO2007115372A1 (en)2006-04-102007-10-18Monash UniversityA method of modulating beta-amyloid peptide production
PL2043662T3 (en)2006-07-262016-03-31Intrexon CorpMethods and compositions for treating disease
EP2061504A4 (en)2006-09-202010-01-27Univ Johns Hopkins COMBINATORY THERAPY AGAINST CANCER AND INFECTIOUS DISEASES USING VACCINE AND ANTI-B7-H1
WO2008106584A1 (en)2007-02-282008-09-04Paringenix, Inc.O-desulfated heparins treating acute exacerbations of chronic obstructive pulmonary disease
AU2008260447B2 (en)*2007-06-012013-10-10Abraxis Bioscience, LlcMethods and compositions for treating recurrent cancer
JP2010534672A (en)2007-07-232010-11-11ユニバーシティ オブ ユタ リサーチ ファウンデーション Method for blocking glycation end product receptor (RAGE) ligation
US8569262B2 (en)2007-11-022013-10-29Momenta Pharmaceuticals, Inc.Polysaccharide compositions and methods of use for the treatment and prevention of disorders associated with progenitor cell mobilization
WO2009117677A2 (en)2008-03-212009-09-24University Of Utah Research FoundationMethods for controlling intracellular calcium levels associated with an ischemic event
BRPI0909849A2 (en)2008-04-042015-10-06Univ Utah Res Found semi-synthetic glycosaminoglycosane ethers and methods for making and using them
US8476249B2 (en)*2009-05-072013-07-02Glaxosmithkline LlcMethod of treating thrombocytopenia
EP2482903B1 (en)2009-09-292018-11-14Vectura GmbHImproved method for treatment of patients with cystic fibrosis
WO2011109877A1 (en)2010-03-122011-09-15The Australian National UniversityHeparan sulfate replacement therapy
WO2011116954A2 (en)*2010-03-242011-09-29Bioréalités S.A.S.Prophylaxis of colorectal and gastrointestinal cancer
US10159705B2 (en)2010-06-282018-12-25Stemtech IP Holdings, LLCMethods and compositions for enhancing stem cell mobilization
WO2012106299A1 (en)*2011-01-312012-08-09Celgene CorporationPharmaceutical compositions of cytidine analogs and methods of use thereof
WO2012106379A1 (en)2011-02-012012-08-09Paringenix, Inc.Sensitization of cancer cells to treatment
WO2013016181A1 (en)2011-07-222013-01-31Paringenix, Inc.Compositions and methods for anti-coagulation
CA2872104A1 (en)2012-05-012013-11-07Duke UniversityCompositions and methods for heparan sulfate as a biomarker for transplant rejection
CN108498532B (en)2012-05-092021-07-23坎泰克斯制药股份有限公司Treatment of myelosuppression
WO2014134539A1 (en)2013-02-282014-09-04President And Fellows Of Harvard CollegeMethods and compositions for mobilizing stem cells
CN105848672A (en)2013-10-222016-08-10坎泰克斯制药股份有限公司Methods of treating and preventing radiation damage
US20160296552A1 (en)2013-10-242016-10-13Cantex Pharmaceuticals, Inc.Treating Bacterial Infections of the Lung
WO2015142924A1 (en)2014-03-172015-09-24Cantex Pharmaceuticals, Inc.Multivalent cation formulations of partially desulfated heparins
EP3258941A4 (en)2015-02-172018-09-26Cantex Pharmaceuticals, Inc.Treatment of cancers and hematopoietic stem cell disorders privileged by cxcl12-cxcr4 interaction
WO2016133907A1 (en)2015-02-172016-08-25Cantex Pharmaceuticals, Inc.Adoptive cell transfer methods
US20170106011A1 (en)2015-10-202017-04-20Cantex Pharmaceuticals, Inc.Methods of treating traumatic brain injury and sequelae
WO2017123549A1 (en)2016-01-112017-07-20Cantex Pharmaceuticals, Inc.Methods of treating or preventing graft-versus-host disease using hmgb1-interacting heparinoids

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CA2872855C (en)2021-07-27
CL2021000008A1 (en)2021-06-11
US20160213706A1 (en)2016-07-28
JP6726252B2 (en)2020-07-22
BR112014028094A2 (en)2020-06-30
JP2019026647A (en)2019-02-21
KR20200118510A (en)2020-10-15
HK1207574A1 (en)2016-02-05
KR20150023361A (en)2015-03-05
LT2846809T (en)2021-01-25
EA029382B1 (en)2018-03-30
CA3122808A1 (en)2013-11-14
US9271999B2 (en)2016-03-01
EA201492052A1 (en)2015-08-31
CA2872855A1 (en)2013-11-14
US20130303481A1 (en)2013-11-14
US20200038431A1 (en)2020-02-06
US20180296590A1 (en)2018-10-18
AU2013260101B2 (en)2016-10-27
DK2846809T3 (en)2021-01-18
US20220354882A1 (en)2022-11-10
MX2019009437A (en)2019-10-02
EP2846809A1 (en)2015-03-18
JP6177885B2 (en)2017-08-09
JP6448694B2 (en)2019-01-09
EP2846809A4 (en)2015-12-30
US8734804B2 (en)2014-05-27
US20130323230A1 (en)2013-12-05
AU2013260101A1 (en)2014-12-18
CN104411316A (en)2015-03-11
CN104411316B (en)2018-05-01
CN108498532A (en)2018-09-07
CN113521093A (en)2021-10-22
ES2848050T3 (en)2021-08-05
CN108498532B (en)2021-07-23
EP2846809B1 (en)2020-10-14
US11229664B2 (en)2022-01-25
MX2014013633A (en)2015-07-06
KR102452803B1 (en)2022-10-07
EP3785720A1 (en)2021-03-03
CL2014003017A1 (en)2015-07-10
MX384023B (en)2025-03-14
IL235593A0 (en)2015-01-29
PT2846809T (en)2021-02-05
SG10201603059YA (en)2016-05-30
BR112014028094B1 (en)2022-03-03
MX370567B (en)2019-12-17
SG10201914117QA (en)2020-02-27
KR102165348B1 (en)2020-10-14
JP2015521176A (en)2015-07-27
PL2846809T3 (en)2021-07-26
JP2017105850A (en)2017-06-15
WO2013169355A1 (en)2013-11-14
IL235593B (en)2019-06-30
HUE053247T2 (en)2021-06-28

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