SG10201913155QA - Adam6 mice - Google Patents

First worldwide family litigation filedlitigationCriticalhttps://patents.darts-ip.com/?family=45998616&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SG10201913155Q(A)"Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2012-02-24Application filed by Regeneron PharmafiledCriticalRegeneron Pharma

2020-02-27Publication of SG10201913155QApublicationCriticalpatent/SG10201913155QA/en

Classifications

- B—PERFORMING OPERATIONS; TRANSPORTING
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- B60H—ARRANGEMENTS OF HEATING, COOLING, VENTILATING OR OTHER AIR-TREATING DEVICES SPECIALLY ADAPTED FOR PASSENGER OR GOODS SPACES OF VEHICLES
- B60H1/00—Heating, cooling or ventilating [HVAC] devices
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- A—HUMAN NECESSITIES
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- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
- A01K67/027—New or modified breeds of vertebrates
- A—HUMAN NECESSITIES
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- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
- A01K67/027—New or modified breeds of vertebrates
- A01K67/0275—Genetically modified vertebrates, e.g. transgenic
- A01K67/0278—Knock-in vertebrates, e.g. humanised vertebrates
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- A01K67/0275—Genetically modified vertebrates, e.g. transgenic
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- B60H1/32—Cooling devices
- B60H1/3204—Cooling devices using compression
- B60H1/3228—Cooling devices using compression characterised by refrigerant circuit configurations
- B60H1/32281—Cooling devices using compression characterised by refrigerant circuit configurations comprising a single secondary circuit, e.g. at evaporator or condenser side
- B—PERFORMING OPERATIONS; TRANSPORTING
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- B60H1/3204—Cooling devices using compression
- B60H1/323—Cooling devices using compression characterised by comprising auxiliary or multiple systems, e.g. plurality of evaporators, or by involving auxiliary cooling devices
- C—CHEMISTRY; METALLURGY
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- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
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- C07K16/462—Igs containing a variable region (Fv) from one specie and a constant region (Fc) from another
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/8509—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2207/00—Modified animals
- A01K2207/15—Humanized animals
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/07—Animals genetically altered by homologous recombination
- A01K2217/072—Animals genetically altered by homologous recombination maintaining or altering function, i.e. knock in
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- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/15—Animals comprising multiple alterations of the genome, by transgenesis or homologous recombination, e.g. obtained by cross-breeding
- A—HUMAN NECESSITIES
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- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2227/00—Animals characterised by species
- A01K2227/10—Mammal
- A01K2227/105—Murine
- A—HUMAN NECESSITIES
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- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2267/00—Animals characterised by purpose
- A01K2267/01—Animal expressing industrially exogenous proteins
- B—PERFORMING OPERATIONS; TRANSPORTING
- B60—VEHICLES IN GENERAL
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- B60H1/00—Heating, cooling or ventilating [HVAC] devices
- B60H1/00642—Control systems or circuits; Control members or indication devices for heating, cooling or ventilating devices
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- B60H2001/002—Distribution of conditionned air to front and rear part of passenger compartment
- C—CHEMISTRY; METALLURGY
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- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
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- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
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- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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- C12N2800/20—Pseudochromosomes, minichrosomosomes
- C12N2800/204—Pseudochromosomes, minichrosomosomes of bacterial origin, e.g. BAC
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2800/00—Nucleic acids vectors
- C12N2800/30—Vector systems comprising sequences for excision in presence of a recombinase, e.g. loxP or FRT

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Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Genetics & Genomics (AREA)
Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Immunology (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Zoology (AREA)
Biophysics (AREA)
Medicinal Chemistry (AREA)
Biotechnology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Environmental Sciences (AREA)
Biomedical Technology (AREA)
Wood Science & Technology (AREA)
Bioinformatics & Cheminformatics (AREA)
General Engineering & Computer Science (AREA)
Veterinary Medicine (AREA)
Physics & Mathematics (AREA)
Biodiversity & Conservation Biology (AREA)
Microbiology (AREA)
Animal Behavior & Ethology (AREA)
Animal Husbandry (AREA)
Thermal Sciences (AREA)
Mechanical Engineering (AREA)
Plant Pathology (AREA)
Toxicology (AREA)
Gastroenterology & Hepatology (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Peptides Or Proteins (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Coloring Foods And Improving Nutritive Qualities (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
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SG10201913155QA2011-02-252012-02-24Adam6 miceSG10201913155QA (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date
US201161446895P	2011-02-25	2011-02-25
US201161497650P	2011-06-16	2011-06-16
US201261595200P	2012-02-06	2012-02-06

Publications (1)

Publication Number	Publication Date
SG10201913155QAtrue SG10201913155QA (en)	2020-02-27

Family

ID=45998616

Family Applications (4)

Application Number	Title	Priority Date	Filing Date
SG10201405135RASG10201405135RA (en)	2011-02-25	2012-02-24	Adam6 mice
SG10201913160QASG10201913160QA (en)	2011-02-25	2012-02-24	Adam6 mice
SG2013064159ASG192933A1 (en)	2011-02-25	2012-02-24	Adam6 mice
SG10201913155QASG10201913155QA (en)	2011-02-25	2012-02-24	Adam6 mice

Family Applications Before (3)

Application Number	Title	Priority Date	Filing Date
SG10201405135RASG10201405135RA (en)	2011-02-25	2012-02-24	Adam6 mice
SG10201913160QASG10201913160QA (en)	2011-02-25	2012-02-24	Adam6 mice
SG2013064159ASG192933A1 (en)	2011-02-25	2012-02-24	Adam6 mice

Country Status (31)

Country	Link
US (12)	US8642835B2 (en)
EP (7)	EP3744850A1 (en)
JP (8)	JP2014507137A (en)
KR (1)	KR101387377B1 (en)
CN (2)	CN105861548B (en)
AU (5)	AU2012243291B2 (en)
BR (1)	BR112013021771B1 (en)
CA (1)	CA2820824A1 (en)
CY (5)	CY1116301T1 (en)
DE (5)	DE12716101T1 (en)
DK (6)	DK2813573T1 (en)
ES (6)	ES2805364T3 (en)
FI (3)	FI2578688T4 (en)
HR (5)	HRP20230526T1 (en)
HU (5)	HUE046746T2 (en)
IL (4)	IL226727A (en)
IN (1)	IN2013CN07629A (en)
LT (4)	LT2578688T (en)
ME (3)	ME02106B (en)
MX (3)	MX375115B (en)
MY (1)	MY172713A (en)
NZ (2)	NZ731926A (en)
PL (5)	PL2738259T3 (en)
PT (5)	PT2738259T (en)
RS (5)	RS64280B1 (en)
RU (2)	RU2582261C2 (en)
SG (4)	SG10201405135RA (en)
SI (5)	SI2738259T1 (en)
SM (5)	SMT201900744T1 (en)
WO (1)	WO2012141798A1 (en)
ZA (1)	ZA201305998B (en)

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EP2395016A3 (en)	2003-05-30	2012-12-19	Merus B.V.	Design and use of paired variable regions of specific binding molecules
US20100069614A1 (en)	2008-06-27	2010-03-18	Merus B.V.	Antibody producing non-human mammals
LT2311874T (en)	2004-07-22	2017-11-27	Erasmus University Medical Center Rotterdam	Binding molecules
GB0905023D0 (en)	2009-03-24	2009-05-06	Univ Erasmus Medical Ct	Binding molecules
EP3241435B1 (en)	2009-07-08	2021-05-26	Kymab Limited	Animal models and therapeutic molecules
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US9796788B2 (en)	2010-02-08	2017-10-24	Regeneron Pharmaceuticals, Inc.	Mice expressing a limited immunoglobulin light chain repertoire
PT2505654T (en)	2010-02-08	2016-11-18	Regeneron Pharma	Common light chain mouse
US20130045492A1 (en)	2010-02-08	2013-02-21	Regeneron Pharmaceuticals, Inc.	Methods For Making Fully Human Bispecific Antibodies Using A Common Light Chain
MX345251B (en)	2010-08-02	2017-01-23	Regeneron Pharma	Mice that make binding proteins comprising vl domains.
HRP20230526T1 (en)	2011-02-25	2023-09-01	Regeneron Pharmaceuticals, Inc.	Adam6 mice
CA2841376C (en)	2011-07-05	2023-02-28	Duke University	N-terminal deleted gp120 immunogens
SG10201606158TA (en)*	2011-08-05	2016-09-29	Regeneron Pharma	Humanized universal light chain mice
CN106995822B (en)	2011-09-19	2021-06-29	科马布有限公司	Antibodies, variable domains and chains tailored for human use
JP2014531452A (en)	2011-09-19	2014-11-27	カイマブ・リミテッド	Animals, repertoire and methods
WO2013045916A1 (en)	2011-09-26	2013-04-04	Kymab Limited	Chimaeric surrogate light chains (slc) comprising human vpreb
CA2850745C (en)	2011-10-03	2022-12-13	Duke University	Vaccine
KR20160098514A (en)	2011-10-17	2016-08-18	리제너론 파아마슈티컬스, 인크.	Restricted immunoglobulin heavy chain mice
US9253965B2 (en)	2012-03-28	2016-02-09	Kymab Limited	Animal models and therapeutic molecules
GB201122047D0 (en)*	2011-12-21	2012-02-01	Kymab Ltd	Transgenic animals
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Publication	Publication Date	Title
IL273986B (en)	2021-04-29	Adam6 mice
AP2014007621A0 (en)	2014-05-31	2-Thiopyrimidinones
AU339404S (en)	2011-11-14	Pen
GB201109865D0 (en)	2011-07-27	Touchiness interaction
AP00723S1 (en)	2015-09-30	Autorickshaw
AU2011303V (en)	2013-09-04	Silverado Dianella tasmanica
AU339857S (en)	2011-12-12	Orchidometer
AU338110S (en)	2011-08-16	Barstool
AU338420S (en)	2011-09-07	Kettlebell
AP2011000390S (en)	2011-05-30	Kuppkraft
AU2011035V (en)	2011-07-05	DBK02 Babingtonia virgata

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