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SG10201404218VA - Super Fast-Acting Insulin Compositions - Google Patents

Super Fast-Acting Insulin Compositions

Info

Publication number
SG10201404218VA
SG10201404218VASG10201404218VASG10201404218VASG10201404218VASG 10201404218V ASG10201404218V ASG 10201404218VASG 10201404218V ASG10201404218V ASG 10201404218VASG 10201404218V ASG10201404218V ASG 10201404218VASG 10201404218V ASG10201404218V ASG 10201404218VA
Authority
SG
Singapore
Prior art keywords
acting insulin
super fast
insulin compositions
compositions
super
Prior art date
Application number
SG10201404218VA
Inventor
Gregory I Frost
Igor Bilinsky
Daniel Vaughn
Barry Sugarman
Original Assignee
Halozyme Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filedlitigationCriticalhttps://patents.darts-ip.com/?family=41037892&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SG10201404218V(A)"Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Halozyme IncfiledCriticalHalozyme Inc
Publication of SG10201404218VApublicationCriticalpatent/SG10201404218VA/en

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SG10201404218VA2008-04-282009-04-28Super Fast-Acting Insulin CompositionsSG10201404218VA (en)

Applications Claiming Priority (2)

Application NumberPriority DateFiling DateTitle
US12583508P2008-04-282008-04-28
US12704408P2008-05-092008-05-09

Publications (1)

Publication NumberPublication Date
SG10201404218VAtrue SG10201404218VA (en)2014-10-30

Family

ID=41037892

Family Applications (1)

Application NumberTitlePriority DateFiling Date
SG10201404218VASG10201404218VA (en)2008-04-282009-04-28Super Fast-Acting Insulin Compositions

Country Status (28)

CountryLink
US (3)US8318154B2 (en)
EP (2)EP2705850B1 (en)
JP (3)JP2011523940A (en)
KR (2)KR101516464B1 (en)
CN (1)CN102083458B (en)
AR (1)AR072250A1 (en)
AU (1)AU2009241795B2 (en)
BR (1)BRPI0911782A2 (en)
CA (1)CA2722628C (en)
CL (1)CL2009001014A1 (en)
CY (1)CY1116311T1 (en)
DK (1)DK2300046T3 (en)
EA (1)EA029502B1 (en)
ES (2)ES2572267T3 (en)
HR (1)HRP20150313T1 (en)
IL (1)IL208554A0 (en)
MX (2)MX348276B (en)
NZ (1)NZ588748A (en)
PE (2)PE20141384A1 (en)
PL (1)PL2300046T3 (en)
PT (1)PT2300046E (en)
RS (1)RS53945B1 (en)
SG (1)SG10201404218VA (en)
SI (1)SI2300046T1 (en)
TW (1)TWI394580B (en)
UY (1)UY31789A1 (en)
WO (1)WO2009134380A2 (en)
ZA (1)ZA201007403B (en)

Families Citing this family (152)

* Cited by examiner, † Cited by third party
Publication numberPriority datePublication dateAssigneeTitle
EP2218779A1 (en)2002-12-162010-08-18Halozyme, Inc.Human chondroitinase glycoprotein (chasegp), process for preparing the same, and pharmaceutical compositions comprising thereof
CN1942588B (en)2003-03-052013-06-12海洋酶公司 Soluble hyaluronidase glycoproteins (sHASEGP), methods for their preparation, their use and pharmaceutical compositions comprising them
US20060104968A1 (en)2003-03-052006-05-18Halozyme, Inc.Soluble glycosaminoglycanases and methods of preparing and using soluble glycosaminogly ycanases
US7871607B2 (en)2003-03-052011-01-18Halozyme, Inc.Soluble glycosaminoglycanases and methods of preparing and using soluble glycosaminoglycanases
ES2613152T3 (en)2008-01-092017-05-22Sanofi-Aventis Deutschland Gmbh New insulin derivatives with extremely delayed time / action profile
CN101970650B (en)2008-03-062017-07-25哈洛齐梅公司 Large-scale production of soluble hyaluronidase
TWI532498B (en)2008-03-172016-05-11巴克斯特保健公司 Combination and method for subcutaneous administration of immunoglobulin and hyaluronic acid
ES2670793T3 (en)*2008-04-042018-06-01Hygieia, Inc. Apparatus for optimizing an insulin dosage regimen for a patient
SG187427A1 (en)*2008-04-142013-02-28Halozyme IncModified hyaluronidases and uses in treating hyaluronan-associated diseases and conditions
TWI394580B (en)2008-04-282013-05-01Halozyme IncSuper fast-acting insulin compositions
TWI451876B (en)*2008-06-132014-09-11Lilly Co EliPegylated insulin lispro compounds
US7959598B2 (en)2008-08-202011-06-14Asante Solutions, Inc.Infusion pump systems and methods
CR20170369A (en)2008-10-172017-11-01Sanofi Aventis Deutschland COMBINATION OF AN INSULIN AND A GLP-1 AGONIST (Divisional 2011-0188)
ES2724588T3 (en)*2008-12-092019-09-12Halozyme Inc Extended soluble PH20 polypeptides and uses thereof
WO2010068907A2 (en)*2008-12-112010-06-17Mefford Scientific, LlcCompositions of proton pump inhibitors and insulin secretagogues, kits and methods of their use to treat diabetes
US9060927B2 (en)*2009-03-032015-06-23Biodel Inc.Insulin formulations for rapid uptake
CN102596175A (en)*2009-07-062012-07-18赛诺菲-安万特德国有限公司Aqueous insulin preparations containing methionine
CA2774053C (en)2009-09-172015-04-28Baxter Healthcare, S.A.Stable co-formulation of hyaluronidase and immunoglobulin, and methods of use thereof
PL2498802T3 (en)2009-11-132015-06-30Sanofi Aventis DeutschlandPharmaceutical composition comprising a glp-1 agonist, an insulin, and methionine
WO2011058082A1 (en)2009-11-132011-05-19Sanofi-Aventis Deutschland GmbhPharmaceutical composition comprising a glp-1 agonist and methionine
US10842951B2 (en)2010-01-122020-11-24Aerami Therapeutics, Inc.Liquid insulin formulations and methods relating thereto
US9180261B2 (en)2010-01-122015-11-10Dance Biopharm Inc.Preservative free insulin formulations and systems and methods for aerosolizing
US9144586B2 (en)*2010-04-072015-09-29Incube Labs, LlcMethod for treating glucose related disorders using stem cell-derived gastro-intestinal cells
CA2805031A1 (en)*2010-07-072012-01-12Biodel, Inc.Compositions and methods for modulating the pharmacokinetics and pharmacodynamics of insulin
EP2595624B1 (en)2010-07-202018-01-31Halozyme, Inc.Methods of treatment or prevention of the adverse side-effects associated with administration of an anti-hyaluronan agent
SG187904A1 (en)2010-08-302013-04-30Sanofi Aventis DeutschlandUse of ave0010 for the manufacture of a medicament for the treatment of diabetes mellitus type 2
US9821032B2 (en)2011-05-132017-11-21Sanofi-Aventis Deutschland GmbhPharmaceutical combination for improving glycemic control as add-on therapy to basal insulin
US9993529B2 (en)2011-06-172018-06-12Halozyme, Inc.Stable formulations of a hyaluronan-degrading enzyme
JP5890516B2 (en)*2011-06-172016-03-22ハロザイム インコーポレイテッド Continuous subcutaneous insulin infusion method using hyaluronan degrading enzyme
EA033472B1 (en)*2011-06-172019-10-31Halozyme IncComposition for stabilization of hyaluronidase and use thereof
EP2543725A1 (en)*2011-07-082013-01-09Biomay AgPolysaccharide lyases
DK2741765T3 (en)*2011-08-102016-06-13Adocia Injectable solution of at least one type of basal insulin
EP2750699B1 (en)2011-08-292015-07-22Sanofi-Aventis Deutschland GmbHPharmaceutical combination for use in glycemic control in diabetes type 2 patients
TWI559929B (en)2011-09-012016-12-01Sanofi Aventis DeutschlandPharmaceutical composition for use in the treatment of a neurodegenerative disease
WO2013040501A1 (en)*2011-09-162013-03-21Pharmathene, Inc.Compositions and combinations of organophosphorus bioscavengers and hyaluronan-degrading enzymes, and uses thereof
EA030440B1 (en)2011-10-242018-08-31Галозим, Инк.Companion diagnostic for anti-hyaluronan agent therapy and methods of use thereof
SMT201900630T1 (en)2011-12-302020-01-14Halozyme IncPh20 polypeptide variants, formulations and uses thereof
CN113730555A (en)2012-01-092021-12-03阿道恰公司Injectable solution of basal insulin and substituted copoly (amino acid) having pH7 and at least PI 5.8 to 8.5
KR101809858B1 (en)2012-04-042017-12-15할로자임, 아이엔씨Combination therapy with an anti-hyaluronan agent and a tumor-targeted taxane
US9381247B2 (en)*2012-04-162016-07-05Biodel Inc.Magnesium compositions for modulating the pharmacokinetics and pharmacodynamics of insulin and insulin analogs, and injection site pain
US9399065B2 (en)2012-04-162016-07-26Biodel Inc.Magnesium compositions for modulating the pharmacokinetics and injection site pain of insulin
US20150314003A2 (en)2012-08-092015-11-05AdociaInjectable solution at ph 7 comprising at least one basal insulin the isoelectric point of which is between 5.8 and 8.5 and a hydrophobized anionic polymer
US9171343B1 (en)2012-09-112015-10-27Aseko, Inc.Means and method for improved glycemic control for diabetic patients
US9897565B1 (en)2012-09-112018-02-20Aseko, Inc.System and method for optimizing insulin dosages for diabetic subjects
EA034393B1 (en)2012-11-132020-02-03АдосиаQuick-acting insulin formulation including a substituted anionic compound
US9486578B2 (en)*2012-12-072016-11-08Animas CorporationMethod and system for tuning a closed-loop controller for an artificial pancreas
CA2889165A1 (en)*2012-12-192014-06-26Wockhardt LimitedA stable aqueous composition comprising human insulin or an analogue or derivative thereof
TWI641381B (en)2013-02-042018-11-21法商賽諾菲公司 Stabilized pharmaceutical formulations of insulin analogs and/or insulin derivatives
ES2709339T3 (en)2013-04-032019-04-16Sanofi Sa Treatment of diabetes mellitus by formulations of long-acting insulins
HK1221415A1 (en)*2013-04-302017-06-02Massachusetts Institute Of TechnologyInjectable nano-network gels for diabetes treatment
ES2708759T3 (en)2013-05-132019-04-11Momenta Pharmaceuticals Inc Procedures for the treatment of neurodegeneration
TW201534726A (en)2013-07-032015-09-16Halozyme IncThermally stable PH20 hyaluronidase variants and uses thereof
US9561324B2 (en)2013-07-192017-02-07Bigfoot Biomedical, Inc.Infusion pump system and method
US20160257754A1 (en)2013-10-162016-09-08Momenta Pharmaceuticals Inc.Sialylated glycoproteins
TW201605489A (en)*2013-10-252016-02-16賽諾菲公司Stable formulation of INSULIN GLULISINE
US10569015B2 (en)2013-12-022020-02-25Bigfoot Biomedical, Inc.Infusion pump system and method
MX2016008977A (en)2014-01-092016-10-04Sanofi SaStabilized pharmaceutical formulations of insulin aspart.
CN105899191B (en)2014-01-092020-06-16赛诺菲Stabilized glycerol-free pharmaceutical formulations of insulin analogues and/or insulin derivatives
JP6641280B2 (en)2014-01-092020-02-05サノフイSanofi Stabilized pharmaceutical formulations of insulin analogues and / or insulin derivatives
GB2523989B (en)2014-01-302020-07-29Insulet Netherlands B VTherapeutic product delivery system and method of pairing
US9486580B2 (en)2014-01-312016-11-08Aseko, Inc.Insulin management
US9233204B2 (en)2014-01-312016-01-12Aseko, Inc.Insulin management
US11039620B2 (en)2014-02-192021-06-22Corning IncorporatedAntimicrobial glass compositions, glasses and polymeric articles incorporating the same
US9622483B2 (en)2014-02-192017-04-18Corning IncorporatedAntimicrobial glass compositions, glasses and polymeric articles incorporating the same
US11039621B2 (en)2014-02-192021-06-22Corning IncorporatedAntimicrobial glass compositions, glasses and polymeric articles incorporating the same
US9732154B2 (en)2014-02-282017-08-15Janssen Biotech, Inc.Anti-CD38 antibodies for treatment of acute lymphoblastic leukemia
US9603927B2 (en)2014-02-282017-03-28Janssen Biotech, Inc.Combination therapies with anti-CD38 antibodies
EP3006045B3 (en)2014-10-072021-03-17Cyprumed GmbHPharmaceutical formulations for the oral delivery of peptide or protein drugs
US11081226B2 (en)2014-10-272021-08-03Aseko, Inc.Method and controller for administering recommended insulin dosages to a patient
CA2927335C (en)2014-10-272023-05-02Aseko, Inc.Subcutaneous outpatient management
PH12017500935A1 (en)*2014-11-212017-11-27Merck Sharp & DohmeInsulin receptor partial agonists
SG11201704390PA (en)2014-12-042017-06-29Janssen Biotech IncAnti-cd38 antibodies for treatment of acute myeloid leukemia
EP3229828B1 (en)2014-12-122023-04-05Sanofi-Aventis Deutschland GmbHInsulin glargine/lixisenatide fixed ratio formulation
TW201630622A (en)2014-12-162016-09-01美國禮來大藥廠 Fast-acting insulin composition
JP2018505756A (en)2015-02-182018-03-01インシュレット コーポレイション Fluid delivery and infusion device and method of use thereof
WO2016137569A1 (en)*2015-02-252016-09-01Dance Biopharm, Inc.Liquid insulin formulations and methods relating thereto
TWI748945B (en)2015-03-132021-12-11德商賽諾菲阿凡提斯德意志有限公司Treatment type 2 diabetes mellitus patients
TW201705975A (en)2015-03-182017-02-16賽諾菲阿凡提斯德意志有限公司Treatment of type 2 diabetes mellitus patients
US9981021B1 (en)*2015-04-092018-05-29Kinetiq, Inc.Subcutaneous therapeutic enzyme formulations, uses, and methods for generating thereof
US9878097B2 (en)2015-04-292018-01-30Bigfoot Biomedical, Inc.Operating an infusion pump system
DE102015107307B3 (en)*2015-05-112016-09-08Labor L + S Aktiengesellschaft Optical method for assaying hyaluronic acid
KR102602754B1 (en)2015-05-202023-11-14얀센 바이오테크 인코포레이티드 Anti-CD38 antibodies for treating light chain amyloidosis and other CD38-positive hematological malignancies
WO2017031440A1 (en)2015-08-202017-02-23Aseko, Inc.Diabetes management therapy advisor
JO3749B1 (en)2015-08-272021-01-31Lilly Co EliRapid-acting insulin compositions
ES2862425T3 (en)2015-11-032021-10-07Janssen Biotech Inc Subcutaneous formulations of anti-CD38 antibodies and their uses
AU2016385454B2 (en)2016-01-052021-12-16Bigfoot Biomedical, Inc.Operating multi-modal medicine delivery systems
US10449294B1 (en)2016-01-052019-10-22Bigfoot Biomedical, Inc.Operating an infusion pump system
EP3374905A1 (en)2016-01-132018-09-19Bigfoot Biomedical, Inc.User interface for diabetes management system
HK1256995A1 (en)2016-01-142019-10-11Bigfoot Biomedical, Inc.Occlusion resolution in medication delivery devices, systems, and methods
US10806859B2 (en)2016-01-142020-10-20Bigfoot Biomedical, Inc.Adjusting insulin delivery rates
GB201607918D0 (en)2016-05-062016-06-22Arecor LtdNovel formulations
US12383166B2 (en)2016-05-232025-08-12Insulet CorporationInsulin delivery system and methods with risk-based set points
WO2017210242A1 (en)*2016-06-022017-12-07Indiana University Research And Technology CorporationInsulin-nuclear hormone conjugates
US10765807B2 (en)2016-09-232020-09-08Insulet CorporationFluid delivery device with sensor
EP3500161A4 (en)2016-12-122020-01-08Bigfoot Biomedical, Inc. ALARMS AND WARNINGS FOR MEDICINE DELIVERY DEVICES AND RELATED SYSTEMS AND METHODS
US10758675B2 (en)2017-01-132020-09-01Bigfoot Biomedical, Inc.System and method for adjusting insulin delivery
US10500334B2 (en)2017-01-132019-12-10Bigfoot Biomedical, Inc.System and method for adjusting insulin delivery
US10881792B2 (en)2017-01-132021-01-05Bigfoot Biomedical, Inc.System and method for adjusting insulin delivery
EP3568859A1 (en)2017-01-132019-11-20Bigfoot Biomedical, Inc.Insulin delivery methods, systems and devices
AU2018261124B2 (en)2017-05-052021-01-28Ypsomed AgClosed loop control of physiological glucose
EA201992351A1 (en)2017-06-012020-03-26Эли Лилли Энд Компани FAST INSULIN COMPOSITIONS
EP3639168B1 (en)2017-06-152022-05-11Novo Nordisk A/SInsulin titration algorithm based on patient profile
EP3758008A1 (en)2017-06-152020-12-30Novo Nordisk A/SBasal titration with adaptive target glucose level
MA50514A (en)2017-10-312020-09-09Janssen Biotech Inc HIGH-RISK MULTIPLE MYELOMA TREATMENT METHODS
US11901060B2 (en)2017-12-212024-02-13Ypsomed AgClosed loop control of physiological glucose
USD928199S1 (en)2018-04-022021-08-17Bigfoot Biomedical, Inc.Medication delivery device with icons
EP3773474A1 (en)2018-04-042021-02-17Arecor LimitedMedical infusion pump system for the delivery of an insulin compound
US11158413B2 (en)*2018-04-232021-10-26Medtronic Minimed, Inc.Personalized closed loop medication delivery system that utilizes a digital twin of the patient
US11147919B2 (en)2018-04-232021-10-19Medtronic Minimed, Inc.Methodology to recommend and implement adjustments to a fluid infusion device of a medication delivery system
EP4492399A3 (en)2018-05-042025-03-26Insulet CorporationSafety constraints for a control algorithm-based drug delivery system
CA3103479A1 (en)2018-06-222019-12-26Eli Lilly And CompanyInsulin and pramlintide delivery systems, methods, and devices
FR3083984A1 (en)2018-07-232020-01-24Adocia DEVICE FOR INJECTING AN INSULIN SOLUTION (S)
FR3083985A1 (en)2018-07-232020-01-24Adocia DEVICE FOR INJECTING AN INSULIN SOLUTION (S)
WO2019243627A1 (en)2018-06-232019-12-26AdociaDevice for injecting an insulin solution
WO2020069406A1 (en)2018-09-282020-04-02Insulet CorporationActivity mode for artificial pancreas system
US20210388070A1 (en)2018-10-302021-12-16Alexion Pharmaceuticals, Inc.Co-administration of a hyaluronidase and anti-c5 antibody for treatment of complement-associated conditions
USD920343S1 (en)2019-01-092021-05-25Bigfoot Biomedical, Inc.Display screen or portion thereof with graphical user interface associated with insulin delivery
US11986629B2 (en)2019-06-112024-05-21Medtronic Minimed, Inc.Personalized closed loop optimization systems and methods
US11801344B2 (en)2019-09-132023-10-31Insulet CorporationBlood glucose rate of change modulation of meal and correction insulin bolus quantity
US11935637B2 (en)2019-09-272024-03-19Insulet CorporationOnboarding and total daily insulin adaptivity
WO2021065768A1 (en)*2019-09-302021-04-08テルモ株式会社Space-forming agent, subcutaneous injection preparation, and space-forming method
CN115176155A (en)2019-10-252022-10-11塞卡科实验室有限公司Indicator compounds, devices including indicator compounds, and methods of making and using the same
EP4354455A3 (en)2019-12-062024-07-10Insulet CorporationTechniques and devices providing adaptivity and personalization in diabetes treatment
US11833329B2 (en)2019-12-202023-12-05Insulet CorporationTechniques for improved automatic drug delivery performance using delivery tendencies from past delivery history and use patterns
AU2021206190A1 (en)2020-01-062022-08-18Insulet CorporationPrediction of meal and/or exercise events based on persistent residuals
WO2021158580A1 (en)2020-02-032021-08-12Insulet CorporationUse of fuzzy logic in predicting user behavior affecting blood glucose concentration
US11551802B2 (en)2020-02-112023-01-10Insulet CorporationEarly meal detection and calorie intake detection
US11986630B2 (en)2020-02-122024-05-21Insulet CorporationDual hormone delivery system for reducing impending hypoglycemia and/or hyperglycemia risk
US11324889B2 (en)2020-02-142022-05-10Insulet CorporationCompensation for missing readings from a glucose monitor in an automated insulin delivery system
US20230190881A1 (en)2020-02-172023-06-22Biotest AgSubcutaneous administration of factor viii
US11607493B2 (en)2020-04-062023-03-21Insulet CorporationInitial total daily insulin setting for user onboarding
WO2022020197A1 (en)2020-07-222022-01-27Insulet CorporationOpen-loop insulin delivery basal parameters based on insulin delivery records
US11684716B2 (en)2020-07-312023-06-27Insulet CorporationTechniques to reduce risk of occlusions in drug delivery systems
US20220062545A1 (en)*2020-08-312022-03-03Insulet CorporationTechniques for determining insulin formulations in an automated insulin delivery system
EP4221785A1 (en)2020-09-302023-08-09Insulet CorporationDrug delivery device with integrated optical-based glucose monitor
WO2022072383A1 (en)2020-09-302022-04-07Cercacor Laboratories, Inc.Insulin formulations and uses in infusion devices
WO2022072618A1 (en)2020-09-302022-04-07Insulet CorporationSecure wireless communications between a glucose monitor and other devices
WO2022098906A1 (en)*2020-11-042022-05-12The Trustees Of The University Of PennsylvaniaViral vectors encoding canine insulin for treatment of metabolic diseases in dogs
US11160925B1 (en)2021-01-292021-11-02Insulet CorporationAutomatic drug delivery system for delivery of a GLP-1 therapeutic
EP4305636A1 (en)2021-03-102024-01-17Insulet CorporationA medicament delivery device with an adjustable and piecewise analyte level cost component to address persistent positive analyte level excursions
US11904140B2 (en)2021-03-102024-02-20Insulet CorporationAdaptable asymmetric medicament cost component in a control system for medicament delivery
EP4101482A1 (en)2021-06-072022-12-14Insulet CorporationExercise safety prediction based on physiological conditions
US11738144B2 (en)2021-09-272023-08-29Insulet CorporationTechniques enabling adaptation of parameters in aid systems by user input
IL315354A (en)*2022-03-012024-11-01Scout Bio IncInsulin fusion protein
CN119487078A (en)*2022-03-012025-02-18宾夕法尼亚州大学信托人 Viral vector genome encoding insulin fusion protein
WO2023178158A1 (en)*2022-03-182023-09-21Mannkind CorporationOptimization of dosing and prescribing of medication
CN114634920B (en)*2022-03-242024-02-27江南大学Recombinant pichia pastoris for producing human hyaluronidase PH20 and construction method thereof
CN114632092B (en)*2022-05-172022-08-23北京第一生物化学药业有限公司Application of testis tablet in preparing medicine with hypoglycemic activity
CN115227724B (en)*2022-09-212023-03-24首都医科大学附属北京友谊医院Use of staphylococcus lentus in preparation of composition
AR131148A1 (en)*2022-11-262025-02-19Obshchestvo S Ogranichennoy Otvetstvennostyu «Geropharm» Rapid-acting insulin compositions (variants thereof)
WO2024138188A1 (en)2022-12-222024-06-27Halozyme, Inc.Hyaluronidase enzyme formulations for high volume administration
US12097355B2 (en)2023-01-062024-09-24Insulet CorporationAutomatically or manually initiated meal bolus delivery with subsequent automatic safety constraint relaxation

Family Cites Families (143)

* Cited by examiner, † Cited by third party
Publication numberPriority datePublication dateAssigneeTitle
US467840A (en)1892-01-26Water-wheel
US3837339A (en)*1972-02-031974-09-24Whittaker CorpBlood glucose level monitoring-alarm system and method therefor
US4179337A (en)1973-07-201979-12-18Davis Frank FNon-immunogenic polypeptides
US4002531A (en)1976-01-221977-01-11Pierce Chemical CompanyModifying enzymes with polyethylene glycol and product produced thereby
US4573994A (en)1979-04-271986-03-04The Johns Hopkins UniversityRefillable medication infusion apparatus
US4373527B1 (en)1979-04-271995-06-27Univ Johns HopkinsImplantable programmable medication infusion system
JPS5951355A (en)1982-09-171984-03-24Fujirebio IncReagent for detecting antiviral antibody
US4685903A (en)1984-01-061987-08-11Pacesetter Infusion, Ltd.External infusion pump apparatus
US4562751A (en)1984-01-061986-01-07Nason Clyde KSolenoid drive apparatus for an external infusion pump
US4894443A (en)1984-02-081990-01-16Cetus CorporationToxin conjugates
US4952496A (en)1984-03-301990-08-28Associated Universities, Inc.Cloning and expression of the gene for bacteriophage T7 RNA polymerase
EP0162007A1 (en)1984-04-181985-11-21Geriaco AGStable and durable insulin preparation for Acne vulgaris treatment
PH25772A (en)1985-08-301991-10-18Novo Industri AsInsulin analogues, process for their preparation
US5052558A (en)1987-12-231991-10-01Entravision, Inc.Packaged pharmaceutical product
WO1989006989A1 (en)1988-01-291989-08-10The Regents Of The University Of CaliforniaIontophoretic non-invasive sampling or delivery device
US4973318A (en)1988-02-101990-11-27D.C.P. Af 1988 A/SDisposable syringe
US5033352A (en)1989-01-191991-07-23Yamaha CorporationElectronic musical instrument with frequency modulation
US5514646A (en)1989-02-091996-05-07Chance; Ronald E.Insulin analogs modified at position 29 of the B chain
US5324844A (en)1989-04-191994-06-28Enzon, Inc.Active carbonates of polyalkylene oxides for modification of polypeptides
US5122614A (en)1989-04-191992-06-16Enzon, Inc.Active carbonates of polyalkylene oxides for modification of polypeptides
DE3921528A1 (en)1989-06-301991-01-10Draegerwerk Ag MEASURING CELL FOR ELECTROCHEMICAL GAS DETECTION
US6552170B1 (en)1990-04-062003-04-22Amgen Inc.PEGylation reagents and compounds formed therewith
US5721348A (en)1990-12-141998-02-24University Of ConnecticutDNA encoding PH-20 proteins
DK134691D0 (en)1991-07-121991-07-12Novo Nordisk As APPARATUS
DK175491D0 (en)1991-10-181991-10-18Novo Nordisk As APPARATUS
US5323907A (en)1992-06-231994-06-28Multi-Comp, Inc.Child resistant package assembly for dispensing pharmaceutical medications
US5433197A (en)1992-09-041995-07-18Stark; Edward W.Non-invasive glucose measurement method and apparatus
WO1994028024A1 (en)1993-06-011994-12-08Enzon, Inc.Carbohydrate-modified polymer conjugates with erythropoietic activity
US5643575A (en)1993-10-271997-07-01Enzon, Inc.Non-antigenic branched polymer conjugates
US5919455A (en)1993-10-271999-07-06Enzon, Inc.Non-antigenic branched polymer conjugates
US5446090A (en)1993-11-121995-08-29Shearwater Polymers, Inc.Isolatable, water soluble, and hydrolytically stable active sulfones of poly(ethylene glycol) and related polymers for modification of surfaces and molecules
US5791344A (en)1993-11-191998-08-11Alfred E. Mann Foundation For Scientific ResearchPatient monitoring system
US5497772A (en)1993-11-191996-03-12Alfred E. Mann Foundation For Scientific ResearchGlucose monitoring system
TW565568B (en)1994-03-312003-12-11Amgen IncCompositions and methods for stimulating megakaryocyte growth and differentiation
US5795569A (en)1994-03-311998-08-18Amgen Inc.Mono-pegylated proteins that stimulate megakaryocyte growth and differentiation
US5569186A (en)1994-04-251996-10-29Minimed Inc.Closed loop infusion pump system with removable glucose sensor
US6093563A (en)1994-07-082000-07-25Ibex Technologies R And D, Inc.Chondroitin lyase enzymes
US5657947A (en)*1994-08-241997-08-19Loral Corp.Precision guidance system for aircraft launched bombs
WO1996006641A1 (en)1994-08-291996-03-07Prizm Pharmaceuticals, Inc.Conjugates of vascular endothelial growth factor with targeted agents
US5824784A (en)1994-10-121998-10-20Amgen Inc.N-terminally chemically modified protein compositions and methods
US5932462A (en)1995-01-101999-08-03Shearwater Polymers, Inc.Multiarmed, monofunctional, polymer for coupling to molecules and surfaces
US5586553A (en)1995-02-161996-12-24Minimed Inc.Transcutaneous sensor insertion set
US5747027A (en)1995-04-071998-05-05The Regents Of The University Of CaliforniaBH55 hyaluronidase
US5672662A (en)1995-07-071997-09-30Shearwater Polymers, Inc.Poly(ethylene glycol) and related polymers monosubstituted with propionic or butanoic acids and functional derivatives thereof for biotechnical applications
EP0862648B1 (en)1995-11-222004-10-06Medtronic MiniMed, Inc.Detection of biological molecules using chemical amplification and optical sensors
US6828431B1 (en)1999-04-092004-12-07Corixa CorporationCompositions and methods for the therapy and diagnosis of breast cancer
US5747806A (en)1996-02-021998-05-05Instrumentation Metrics, IncMethod and apparatus for multi-spectral analysis in noninvasive nir spectroscopy
US5866538A (en)1996-06-201999-02-02Novo Nordisk A/SInsulin preparations containing NaCl
US5958750A (en)1996-07-031999-09-28Inctye Pharmaceuticals, Inc.Human hyaluronidase
HUP9904152A3 (en)1996-07-052000-05-29Novo Nordisk AsFlexible piston rod
US5665069A (en)1996-07-191997-09-09Cumer; Patricia LynnPressure-directed peribulbar anesthesia delivery device
US5783556A (en)*1996-08-131998-07-21Genentech, Inc.Formulated insulin-containing composition
US6110149A (en)1996-09-132000-08-29Novo Nordisk A/SSyringe
US5947934A (en)1996-09-131999-09-07Novo Nordisk A/SDose display for an injection syringe
US6379339B1 (en)1996-09-132002-04-30Nova Nordisk A/SSyringe
US6214966B1 (en)1996-09-262001-04-10Shearwater CorporationSoluble, degradable poly(ethylene glycol) derivatives for controllable release of bound molecules into solution
US6123938A (en)1996-10-172000-09-26The Regents Of The University Of CaliforniaHuman urinary hyaluronidase
US6193963B1 (en)1996-10-172001-02-27The Regents Of The University Of CaliforniaMethod of treating tumor-bearing patients with human plasma hyaluronidase
US6258351B1 (en)1996-11-062001-07-10Shearwater CorporationDelivery of poly(ethylene glycol)-modified molecules from degradable hydrogels
US5990237A (en)1997-05-211999-11-23Shearwater Polymers, Inc.Poly(ethylene glycol) aldehyde hydrates and related polymers and applications in modifying amines
US7267665B2 (en)1999-06-032007-09-11Medtronic Minimed, Inc.Closed loop system for controlling insulin infusion
US6558351B1 (en)1999-06-032003-05-06Medtronic Minimed, Inc.Closed loop system for controlling insulin infusion
US6074372A (en)1997-06-092000-06-13Novo Nordisk A/SDose setting mechanism and an injection syringe having such a dose setting mechanism
US5954643A (en)1997-06-091999-09-21Minimid Inc.Insertion set for a transcutaneous sensor
PE79099A1 (en)1997-06-131999-08-24Lilly Co Eli STABLE INSULIN FORMULATIONS
US6093167A (en)1997-06-162000-07-25Medtronic, Inc.System for pancreatic stimulation and glucose measurement
DE19726167B4 (en)1997-06-202008-01-24Sanofi-Aventis Deutschland Gmbh Insulin, process for its preparation and pharmaceutical preparation containing it
WO2001087925A2 (en)2000-05-162001-11-22Bolder Biotechnology, Inc.Methods for refolding proteins containing free cysteine residues
CN1111453C (en)1997-10-092003-06-18塞莫·布莱克·克劳森公司 Rotary refining system and control method thereof
US6448369B1 (en)1997-11-062002-09-10Shearwater CorporationHeterobifunctional poly(ethylene glycol) derivatives and methods for their preparation
US6579690B1 (en)1997-12-052003-06-17Therasense, Inc.Blood analyte monitoring through subcutaneous measurement
US5985263A (en)1997-12-191999-11-16Enzon, Inc.Substantially pure histidine-linked protein polymer conjugates
DK1411075T3 (en)1998-03-122008-10-27Nektar Therapeutics Al Corp Process for Preparation of Polymer Conjugates
CA2336399A1 (en)1998-07-032000-01-13Neles Field Controls OyMethod and arrangement for measuring fluid
US6558320B1 (en)2000-01-202003-05-06Medtronic Minimed, Inc.Handheld personal data assistant (PDA) with a medical device and method of using the same
US6554798B1 (en)1998-08-182003-04-29Medtronic Minimed, Inc.External infusion device with remote programming, bolus estimator and/or vibration alarm capabilities
US6420339B1 (en)1998-10-142002-07-16Amgen Inc.Site-directed dual pegylation of proteins for improved bioactivity and biocompatibility
US6669663B1 (en)*1999-04-302003-12-30Medtronic, Inc.Closed loop medicament pump
JO2291B1 (en)1999-07-022005-09-12اف . هوفمان لاروش ايه جيErythopintin derivatives
US6461802B1 (en)1999-08-022002-10-08Agfa-GevaertAdhesive layer for polyester film
TW453884B (en)1999-09-162001-09-11Novo Nordisk AsDose setting limiter
WO2001046291A1 (en)1999-12-222001-06-28Shearwater CorporationSterically hindered derivatives of water soluble polymers
US6413507B1 (en)1999-12-232002-07-02Shearwater CorporationHydrolytically degradable carbamate derivatives of poly (ethylene glycol)
US20030212021A1 (en)2001-01-252003-11-13Frost Gregory I.Myeloid colony stimulating factor and uses thereof
AU2001226650A1 (en)2000-01-282001-08-07Novo-Nordisk A/SA dose setting limiter
WO2001062827A2 (en)2000-02-222001-08-30Shearwater CorporationN-maleimidyl polymer derivatives
US6586398B1 (en)2000-04-072003-07-01Amgen, Inc.Chemically modified novel erythropoietin stimulating protein compositions and methods
US6442413B1 (en)2000-05-152002-08-27James H. SilverImplantable sensor
US6663602B2 (en)2000-06-162003-12-16Novo Nordisk A/SInjection device
US6589229B1 (en)2000-07-312003-07-08Becton, Dickinson And CompanyWearable, self-contained drug infusion device
EP1345628B1 (en)2000-12-202011-04-13F. Hoffmann-La Roche AGConjugates of erythropoietin (epo) with polyethylene glycol (peg)
TWI246524B (en)2001-01-192006-01-01Shearwater CorpMulti-arm block copolymers as drug delivery vehicles
US6740042B1 (en)2001-09-052004-05-25Biomedix, Inc.Bilateral simultaneous doppler measurement of segmented sphygmomanometry
US6740072B2 (en)2001-09-072004-05-25Medtronic Minimed, Inc.System and method for providing closed loop infusion formulation delivery
US6908963B2 (en)2001-10-092005-06-21Nektar Therapeutics Al, CorporationThioester polymer derivatives and method of modifying the N-terminus of a polypeptide therewith
AU2002352524B2 (en)2001-11-072007-10-04Nektar TherapeuticsBranched polymers and their conjugates
CA2468230A1 (en)2001-11-282003-06-05Neose Technologies, Inc.Glycopeptide remodeling using amidases
US7317000B2 (en)2001-12-022008-01-08Novo Nordisk A/SGlucose-dependent insulins
WO2003047426A1 (en)2001-12-032003-06-12Eli Lilly And CompanyMedication delivery device having communication capability with glucose monitor
US6852104B2 (en)2002-02-282005-02-08Smiths Medical Md, Inc.Programmable insulin pump
US6744350B2 (en)2002-02-282004-06-01Smiths Medical Md, Inc.Insulin pump having missed meal bolus alarm
US7192468B2 (en)2002-04-152007-03-20Fluor Technologies CorporationConfigurations and method for improved gas removal
JP2006505305A (en)2002-08-072006-02-16メムリー コーポレーション Implantable artificial pancreas
KR20040040782A (en)2002-11-082004-05-13선바이오(주)Novel hexa-arm polyethylene glycol and its derivatives and the methods of preparation thereof
EP2218779A1 (en)2002-12-162010-08-18Halozyme, Inc.Human chondroitinase glycoprotein (chasegp), process for preparing the same, and pharmaceutical compositions comprising thereof
SI1596887T1 (en)2003-02-262022-05-31Nektar TherapeuticsPolymer-factor viii moiety conjugates
CN1942588B (en)2003-03-052013-06-12海洋酶公司 Soluble hyaluronidase glycoproteins (sHASEGP), methods for their preparation, their use and pharmaceutical compositions comprising them
US20090123367A1 (en)2003-03-052009-05-14DelfmemsSoluble Glycosaminoglycanases and Methods of Preparing and Using Soluble Glycosaminoglycanases
US7871607B2 (en)2003-03-052011-01-18Halozyme, Inc.Soluble glycosaminoglycanases and methods of preparing and using soluble glycosaminoglycanases
US20060104968A1 (en)2003-03-052006-05-18Halozyme, Inc.Soluble glycosaminoglycanases and methods of preparing and using soluble glycosaminogly ycanases
US7610156B2 (en)2003-03-312009-10-27Xencor, Inc.Methods for rational pegylation of proteins
KR100512483B1 (en)2003-05-072005-09-05선바이오(주)Novel Preparation method of PEG-maleimide PEG derivatives
US7025713B2 (en)2003-10-132006-04-11Icon Ip, Inc.Weight lifting system with internal cam mechanism
JP5022213B2 (en)2004-03-122012-09-12バイオデル, インコーポレイテッド Rapidly acting drug delivery composition
US6999854B2 (en)2004-05-282006-02-14International Business Machines CorporationMedical infusion pump capable of learning bolus time patterns and providing bolus alerts
US7572613B2 (en)2004-06-252009-08-11Klein Jeffrey ADrug delivery system for accelerated subcutaneous absorption
JP3912395B2 (en)*2004-07-122007-05-09セイコーエプソン株式会社 Semiconductor integrated circuit, inspection apparatus, and semiconductor integrated circuit inspection method
US20070244467A1 (en)2005-09-282007-10-18Biodel, Inc., State Of Incorporation DelawareSelf-Filling Two Chamber Injectable Device
WO2007041481A1 (en)2005-09-292007-04-12Biodel, Inc.Rapid acting and prolonged acting insulin preparations
US7713929B2 (en)*2006-04-122010-05-11Biodel Inc.Rapid acting and long acting insulin combination formulations
EP1951198B1 (en)*2005-10-202010-06-16MDRNA, Inc.Intranasal administration of rapid acting insulin
WO2007098058A2 (en)2006-02-162007-08-30Biodel, Inc.Device for sublingual drug delivery using iontophoresis
WO2007098479A2 (en)*2006-02-212007-08-30University Of Medicine And Dentistry Of New JerseyLocalized insulin delivery for bone healing
CA2649109A1 (en)2006-04-122007-10-25Biodel, Inc.Rapid acting and long acting insulin combination formulations
US20070243567A1 (en)2006-04-132007-10-18Syhhong ChangBeta cell mimicking control algorithm for artificial pancreas
US20090325860A1 (en)*2006-08-042009-12-31Nastech Pharmaceutical Company Inc.Compositions for intranasal delivery of human insulin and uses thereof
RU2471867C2 (en)2007-06-192013-01-10Тамара П. УваркинаHyaluronidase and method for using it
IL186598A0 (en)*2007-10-112008-11-03Mohammad AbdulrazikComposition and method for the treatment or prevention of glaucoma and ocular hypertension
CN101970650B (en)2008-03-062017-07-25哈洛齐梅公司 Large-scale production of soluble hyaluronidase
TWI395593B (en)2008-03-062013-05-11Halozyme IncIn vivo temporal control of activatable matrix-degrading enzymes
TWI532498B (en)2008-03-172016-05-11巴克斯特保健公司 Combination and method for subcutaneous administration of immunoglobulin and hyaluronic acid
SG187427A1 (en)2008-04-142013-02-28Halozyme IncModified hyaluronidases and uses in treating hyaluronan-associated diseases and conditions
US20090311237A1 (en)2008-04-142009-12-17Frost Gregory ICombination therapy using a soluble hyaluronidase and a bisphosphonate
TWI394580B (en)2008-04-282013-05-01Halozyme IncSuper fast-acting insulin compositions
TWI532497B (en)2008-08-112016-05-11曼凱公司 Ultra-fast use of insulin
ES2724588T3 (en)2008-12-092019-09-12Halozyme Inc Extended soluble PH20 polypeptides and uses thereof
EP2595624B1 (en)2010-07-202018-01-31Halozyme, Inc.Methods of treatment or prevention of the adverse side-effects associated with administration of an anti-hyaluronan agent
JP2014510045A (en)2011-02-082014-04-24ハロザイム インコーポレイテッド Hyaluronan degrading enzyme composition and lipid preparation and its use for the treatment of benign prostatic hypertrophy
US9993529B2 (en)2011-06-172018-06-12Halozyme, Inc.Stable formulations of a hyaluronan-degrading enzyme
JP5890516B2 (en)2011-06-172016-03-22ハロザイム インコーポレイテッド Continuous subcutaneous insulin infusion method using hyaluronan degrading enzyme
EA030440B1 (en)2011-10-242018-08-31Галозим, Инк.Companion diagnostic for anti-hyaluronan agent therapy and methods of use thereof
SMT201900630T1 (en)2011-12-302020-01-14Halozyme IncPh20 polypeptide variants, formulations and uses thereof
KR101809858B1 (en)2012-04-042017-12-15할로자임, 아이엔씨Combination therapy with an anti-hyaluronan agent and a tumor-targeted taxane

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