PT1594460E - Sustained-release tramadol formulations with 24-hour efficacy - Google Patents

Sustained-release tramadol formulations with 24-hour efficacy Download PDF

Info

Publication number: PT1594460E
Authority: PT; Portugal
Prior art keywords: sustained; release tramadol; tramadol formulations; hour efficacy; efficacy
Prior art date: 2002-10-25

Application number

PT03809237T

Other languages

Portuguese (pt)

Inventor

Vincent Lenaerts

Patricia Laure Ouadji-Njiki

Jonathan Bacon

Rachid Ouzerourou

Sonia Gervais

Miloud Rahmouni

Damon Smith

Original Assignee

Labopharm Inc

Labopharm Europe Ltd

Labopharm Barbados Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-10-25

Filing date

2003-10-27

Publication date

2008-06-27

Family has litigation

First worldwide family litigation filedlitigationCriticalhttps://patents.darts-ip.com/?family=32179487&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT1594460(E)"Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2003-10-27Application filed by Labopharm Inc, Labopharm Europe Ltd, Labopharm Barbados LtdfiledCriticalLabopharm Inc

2008-06-27Publication of PT1594460EpublicationCriticalpatent/PT1594460E/en

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
- A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/2853—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers, poly(lactide-co-glycolide)
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin

Landscapes

Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pain & Pain Management (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicinal Preparation (AREA)

PT03809237T2002-10-252003-10-27Sustained-release tramadol formulations with 24-hour efficacyPT1594460E (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US28102602A	2002-10-25	2002-10-25
US51037803P	2003-10-10	2003-10-10

Publications (1)

Publication Number	Publication Date
PT1594460Etrue PT1594460E (en)	2008-06-27

Family

ID=32179487

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PT03809237TPT1594460E (en)	2002-10-25	2003-10-27	Sustained-release tramadol formulations with 24-hour efficacy

Country Status (11)

Country	Link
JP (1)	JP2006507277A (en)
KR (1)	KR20050083816A (en)
AR (1)	AR045972A1 (en)
AU (1)	AU2003275855B2 (en)
CA (1)	CA2503155A1 (en)
IL (1)	IL168114A (en)
NO (1)	NO20052479L (en)
PT (1)	PT1594460E (en)
RU (1)	RU2328275C2 (en)
UA (1)	UA84277C2 (en)
WO (1)	WO2004037222A2 (en)

Families Citing this family (39)

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US7776314B2 (en)	2002-06-17	2010-08-17	Grunenthal Gmbh	Abuse-proofed dosage system
TWI319713B (en)	2002-10-25	2010-01-21		Sustained-release tramadol formulations with 24-hour efficacy
US8487002B2 (en)	2002-10-25	2013-07-16	Paladin Labs Inc.	Controlled-release compositions
US7413749B2 (en)	2003-03-11	2008-08-19	Purdue Pharma L.P.	Titration dosing regimen for controlled release tramadol
EP1905435A3 (en)*	2003-03-11	2008-05-14	Euro-Celtique S.A.	Titration dosing regimen for controlled release tramadol
DE102005005446A1 (en)	2005-02-04	2006-08-10	Grünenthal GmbH	Break-resistant dosage forms with sustained release
DE10361596A1 (en)	2003-12-24	2005-09-29	Grünenthal GmbH	Process for producing an anti-abuse dosage form
US20070048228A1 (en)	2003-08-06	2007-03-01	Elisabeth Arkenau-Maric	Abuse-proofed dosage form
DE10336400A1 (en)	2003-08-06	2005-03-24	Grünenthal GmbH	Anti-abuse dosage form
NZ551288A (en)*	2004-05-14	2010-10-29	Janssen Pharmaceutica Nv	Carboxamido opioid compounds that are derivatives of tramadol
DE102004032049A1 (en)	2004-07-01	2006-01-19	Grünenthal GmbH	Anti-abuse, oral dosage form
DE102005005449A1 (en)	2005-02-04	2006-08-10	Grünenthal GmbH	Process for producing an anti-abuse dosage form
PT1931346E (en)*	2005-09-09	2012-08-14	Angelini Labopharm Llc	COMPOSITION OF TRAZODONE FOR ADMINISTRATION ONCE A DAY
CA2616204C (en)	2005-09-09	2015-12-01	Labopharm Inc.	Sustained drug release composition
EP2010158B1 (en)*	2006-04-26	2016-02-17	Alphapharm Pty Ltd.	Controlled release formulations comprising uncoated discrete unit(s) and an extended release matrix
WO2009092601A1 (en)	2008-01-25	2009-07-30	Grünenthal GmbH	Pharmaceutical dosage form
HRP20161307T1 (en)	2008-05-09	2016-12-02	Grünenthal GmbH	Process for the preparation of an intermediate powder formulation and a final solid dosage form under usage of a spray congealing step
JP5543963B2 (en)	2008-05-27	2014-07-09	ザユニバーシティーオブメルボルン	Method for treating mammals having Eustachian tube dysfunction
CN107028908A (en)*	2008-10-27	2017-08-11	阿尔扎公司	Extended release oral acetaminophen/tramadol dosage form
ES2428938T3 (en)	2009-07-22	2013-11-12	Grünenthal GmbH	Dosage form resistant to manipulation and stabilized against oxidation
ES2534908T3 (en)	2009-07-22	2015-04-30	Grünenthal GmbH	Hot melt extruded controlled release dosage form
EP2531176B1 (en)	2010-02-03	2016-09-07	Grünenthal GmbH	Preparation of a powdery pharmaceutical composition by means of an extruder
AU2011297892B2 (en)	2010-09-02	2014-05-29	Grunenthal Gmbh	Tamper resistant dosage form comprising an anionic polymer
AU2011297901B2 (en)	2010-09-02	2014-07-31	Grunenthal Gmbh	Tamper resistant dosage form comprising inorganic salt
AU2012292418B2 (en)	2011-07-29	2017-02-16	Grunenthal Gmbh	Tamper-resistant tablet providing immediate drug release
RS56528B1 (en)	2011-07-29	2018-02-28	Gruenenthal Gmbh	Tamper-resistant tablet providing immediate drug release
EP2819656A1 (en)	2012-02-28	2015-01-07	Grünenthal GmbH	Tamper-resistant dosage form comprising pharmacologically active compound and anionic polymer
EP2838512B1 (en)	2012-04-18	2018-08-22	Grünenthal GmbH	Tamper resistant and dose-dumping resistant pharmaceutical dosage form
US10064945B2 (en)	2012-05-11	2018-09-04	Gruenenthal Gmbh	Thermoformed, tamper-resistant pharmaceutical dosage form containing zinc
BR112015029616A2 (en)	2013-05-29	2017-07-25	Gruenenthal Gmbh	tamper-resistant dosage form with bimodal release profile
AU2014273227B2 (en)	2013-05-29	2019-08-15	Grunenthal Gmbh	Tamper-resistant dosage form containing one or more particles
CA2917136C (en)	2013-07-12	2022-05-31	Grunenthal Gmbh	Tamper-resistant dosage form containing ethylene-vinyl acetate polymer
BR112016010482B1 (en)	2013-11-26	2022-11-16	Grünenthal GmbH	PREPARATION OF A PHARMACEUTICAL COMPOSITION IN POWDER BY MEANS OF CRYOMING
JP2017518980A (en)	2014-05-12	2017-07-13	グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング	Anti-modification immediate release capsule formulation containing tapentadol
CA2949422A1 (en)	2014-05-26	2015-12-03	Grunenthal Gmbh	Multiparticles safeguarded against ethanolic dose-dumping
MX2017013637A (en)	2015-04-24	2018-03-08	Gruenenthal Gmbh	Tamper-resistant dosage form with immediate release and resistance against solvent extraction.
WO2017042325A1 (en)	2015-09-10	2017-03-16	Grünenthal GmbH	Protecting oral overdose with abuse deterrent immediate release formulations
KR20190005199A (en)	2016-05-05	2019-01-15	어퀘스티브 테라퓨틱스, 아이엔씨.	Enhanced delivery fffffrin composition
CA3022797A1 (en)*	2016-05-05	2017-11-09	Aquestive Therapeutics, Inc.	Pharmaceutical compositions with enhanced permeation

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NZ260408A (en)*	1993-05-10	1996-05-28	Euro Celtique Sa	Controlled release preparation comprising tramadol
DE19530575A1 (en)*	1995-08-19	1997-02-20	Gruenenthal Gmbh	Rapidly disintegrating drug form of tramadol or a tramadol salt
US6306438B1 (en)*	1997-07-02	2001-10-23	Euro-Celtique, S.A.	Stabilized sustained release tramadol formulations
DE10015479A1 (en)*	2000-03-29	2001-10-11	Basf Ag	Solid oral dosage forms with delayed release of active ingredient and high mechanical stability
US6607748B1 (en)*	2000-06-29	2003-08-19	Vincent Lenaerts	Cross-linked high amylose starch for use in controlled-release pharmaceutical formulations and processes for its manufacture
DE10108122A1 (en)*	2001-02-21	2002-10-02	Gruenenthal Gmbh	Medicines based on tramadol

2003
- 2003-10-27ARARP030103926Apatent/AR045972A1/enunknown
- 2003-10-27WOPCT/CA2003/001638patent/WO2004037222A2/enactiveIP Right Grant
- 2003-10-27RURU2005115855/15Apatent/RU2328275C2/ennot_activeIP Right Cessation
- 2003-10-27JPJP2004545655Apatent/JP2006507277A/enactivePending
- 2003-10-27PTPT03809237Tpatent/PT1594460E/enunknown
- 2003-10-27UAUAA200504852Apatent/UA84277C2/enunknown
- 2003-10-27KRKR1020057007089Apatent/KR20050083816A/ennot_activeCeased
- 2003-10-27CACA002503155Apatent/CA2503155A1/ennot_activeAbandoned
- 2003-10-27AUAU2003275855Apatent/AU2003275855B2/ennot_activeExpired
2005
- 2005-04-19ILIL168114Apatent/IL168114A/enactiveIP Right Grant
- 2005-05-23NONO20052479Apatent/NO20052479L/ennot_activeApplication Discontinuation

Also Published As

Publication number	Publication date
WO2004037222A2 (en)	2004-05-06
JP2006507277A (en)	2006-03-02
AR045972A1 (en)	2005-11-23
KR20050083816A (en)	2005-08-26
AU2003275855A1 (en)	2004-05-13
RU2328275C2 (en)	2008-07-10
CA2503155A1 (en)	2004-05-06
RU2005115855A (en)	2006-01-20
AU2003275855B2 (en)	2009-04-23
WO2004037222A3 (en)	2005-09-22
UA84277C2 (en)	2008-10-10
NO20052479D0 (en)	2005-05-23
NO20052479L (en)	2005-05-23
IL168114A (en)	2011-05-31

Publication	Publication Date	Title
PT1594460E (en)	2008-06-27	Sustained-release tramadol formulations with 24-hour efficacy
IL165349A0 (en)	2006-01-15	Microcapsule formulations
AU2003235759A8 (en)	2003-07-24	4-dedimethylamino tetracycline compounds
GB0206876D0 (en)	2002-05-01	Therapeutic agents
GB0209991D0 (en)	2002-06-12	Therapeutic agents
GB0209995D0 (en)	2002-06-12	Therapeutic agents
GB0209997D0 (en)	2002-06-12	Therapeutic agents
GB0210127D0 (en)	2002-06-12	Therapeutic agents
GB0210124D0 (en)	2002-06-12	Therapeutic agents
AU152934S (en)	2003-08-26	Sofa
AU2003279911A8 (en)	2004-05-04	Therapeutic formulations
EP1673073A4 (en)	2012-03-21	Sustained-release formulations
GB0208394D0 (en)	2002-05-22	Therapeutic agents
GB0217068D0 (en)	2002-08-28	Therapeutic agents
GB0214147D0 (en)	2002-07-31	Formulations
GB0210260D0 (en)	2002-06-12	Pesticides
AU2003277048A8 (en)	2004-04-23	Under bed fumigator
GB0218269D0 (en)	2002-09-11	Disinfectants
GB0227919D0 (en)	2003-01-08	Insecticidal agent
EP1578445A4 (en)	2007-04-04	Therapeutic adjuvant
GB0213383D0 (en)	2002-07-24	Therapeutic conditions
TW561854U (en)	2003-11-11	Assembled bed
CA94977S (en)	2002-03-15	Disinfectant base
CA94979S (en)	2002-03-15	Disinfectant center
PL357479A1 (en)	2004-06-14	Adjuvant for pesticides

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