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NO980155L - Stabilized pharmaceutical composition comprising a growth hormone pre-treated with zinc and optionally lysine or potassium ions - Google Patents

Stabilized pharmaceutical composition comprising a growth hormone pre-treated with zinc and optionally lysine or potassium ions

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Publication number
NO980155L
NO980155LNO980155ANO980155ANO980155LNO 980155 LNO980155 LNO 980155LNO 980155 ANO980155 ANO 980155ANO 980155 ANO980155 ANO 980155ANO 980155 LNO980155 LNO 980155L
Authority
NO
Norway
Prior art keywords
zinc
growth hormone
treated
pharmaceutical composition
potassium ions
Prior art date
Application number
NO980155A
Other languages
Norwegian (no)
Other versions
NO980155D0 (en
Inventor
Thorkild Christensen
Per Balschmidt
Hans Holmegaard Soerensen
Ole Hvilsted Olsen
Lars Thim
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk AsfiledCriticalNovo Nordisk As
Publication of NO980155D0publicationCriticalpatent/NO980155D0/en
Publication of NO980155LpublicationCriticalpatent/NO980155L/en

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Abstract

Translated fromNorwegian

Preparat som omfatter et vekst- hormon som er forbehandlet med sink og eventuelt lysin eller kalsiumioner, og som oppviser en svært høy stabilitet mot deamidering, oksidasjon og spalting av peptidbindinger. Stabiliteten til produktet muliggjør lagring og tran- sport derav i en lyofilisert tilstand eller i form av et oppløst eller gjen- oppløst preparat ved omgivelses- temperatur.Preparation comprising a growth hormone pretreated with zinc and possibly lysine or calcium ions, which exhibits very high stability to deamidation, oxidation and cleavage of peptide bonds. The stability of the product enables storage and transport thereof in a lyophilized state or in the form of a dissolved or redissolved preparation at ambient temperature.

NO980155A1995-07-141998-01-13 Stabilized pharmaceutical composition comprising a growth hormone pre-treated with zinc and optionally lysine or potassium ionsNO980155L (en)

Applications Claiming Priority (2)

Application NumberPriority DateFiling DateTitle
US119395P1995-07-141995-07-14
PCT/DK1996/000293WO1997003692A1 (en)1995-07-141996-06-28A stabilized pharmaceutical formulation comprising a growth hormone pre-treated with zinc and optionally lysine or calcium ions

Publications (2)

Publication NumberPublication Date
NO980155D0 NO980155D0 (en)1998-01-13
NO980155Ltrue NO980155L (en)1998-01-13

Family

ID=21694837

Family Applications (1)

Application NumberTitlePriority DateFiling Date
NO980155ANO980155L (en)1995-07-141998-01-13 Stabilized pharmaceutical composition comprising a growth hormone pre-treated with zinc and optionally lysine or potassium ions

Country Status (14)

CountryLink
EP (1)EP0839049A1 (en)
JP (1)JPH11509212A (en)
KR (1)KR19990028981A (en)
CN (1)CN1190897A (en)
AU (1)AU715997B2 (en)
BR (1)BR9609741A (en)
CA (1)CA2226523A1 (en)
CZ (1)CZ9498A3 (en)
HU (1)HUP9802287A3 (en)
IL (1)IL122583A0 (en)
NO (1)NO980155L (en)
PL (1)PL324379A1 (en)
WO (1)WO1997003692A1 (en)
ZA (1)ZA965368B (en)

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Also Published As

Publication numberPublication date
CA2226523A1 (en)1997-02-06
CN1190897A (en)1998-08-19
HUP9802287A2 (en)1999-02-01
NO980155D0 (en)1998-01-13
WO1997003692A1 (en)1997-02-06
ZA965368B (en)1997-01-14
HUP9802287A3 (en)2000-10-30
PL324379A1 (en)1998-05-25
EP0839049A1 (en)1998-05-06
CZ9498A3 (en)1998-06-17
AU6353496A (en)1997-02-18
JPH11509212A (en)1999-08-17
KR19990028981A (en)1999-04-15
BR9609741A (en)1999-03-16
AU715997B2 (en)2000-02-17
MX9800358A (en)1998-07-31
IL122583A0 (en)1998-06-15

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