| TWI625121B              (zh) | 2009-07-13 | 2018-06-01 | 基利科學股份有限公司 | 調節細胞凋亡信號之激酶的抑制劑 | 
| PL2651417T3              (pl) | 2010-12-16 | 2017-08-31 | Calchan Limited | Pochodne pirolopirymidyny hamujące ASK1 | 
| UY34573A              (es) | 2012-01-27 | 2013-06-28 | Gilead Sciences Inc | Inhibidor de la quinasa que regula la señal de la apoptosis | 
| CA2931615A1              (en) | 2013-11-26 | 2015-06-04 | Gilead Sciences, Inc. | Therapies for treating myeloproliferative disorders | 
| AU2015206194A1              (en) | 2014-01-20 | 2016-07-28 | Gilead Sciences, Inc. | Therapies for treating cancers | 
| WO2015187499A1              (en) | 2014-06-03 | 2015-12-10 | Gilead Sciences, Inc. | Use of an ask1 inhibitor for the treatment of liver disease, optionally in combination with a loxl2 inhibitor | 
| TW201618781A              (zh) | 2014-08-13 | 2016-06-01 | 吉李德科學股份有限公司 | 治療肺高血壓之方法 | 
| EP3197448B1              (en) | 2014-09-24 | 2019-04-24 | Gilead Sciences, Inc. | Methods of treating liver disease | 
| MA41252A              (fr)* | 2014-12-23 | 2017-10-31 | Gilead Sciences Inc | Formes solides d'un inhibiteur d'ask 1 | 
| CN112225699B              (zh) | 2014-12-23 | 2023-11-14 | 吉利德科学公司 | 制备ask1抑制剂的方法 | 
| TW201639573A              (zh) | 2015-02-03 | 2016-11-16 | 吉李德科學股份有限公司 | 有關治療癌症之合併治療 | 
| MD3097102T2              (ro) | 2015-03-04 | 2018-02-28 | Gilead Sciences Inc | Compuşi de 4,6-diamino-pirido[3,2-D]pirimidină modulatori ai receptorilor de tip Toll | 
| EP3456717B1              (en) | 2015-07-06 | 2021-03-17 | Gilead Sciences, Inc. | 4,6-diamino-quinoline-3-carbonitrile derivative as cancer osaka thyroid (cot) modulator for treating inflammatory disease | 
| WO2017059224A2              (en) | 2015-10-01 | 2017-04-06 | Gilead Sciences, Inc. | Combination of a btk inhibitor and a checkpoint inhibitor for treating cancers | 
| JP2018534263A              (ja)* | 2015-10-02 | 2018-11-22 | ギリアード サイエンシーズ, インコーポレイテッド | 癌、アレルギー性障害、自己免疫性疾患または炎症性疾患を治療するための、jak阻害物質、ask1阻害物質、brd阻害物質及び/またはmmp9阻害物質から選択される阻害物質とbtk阻害物質gs−4059の組み合わせ | 
| AU2016370916A1              (en) | 2015-12-17 | 2018-06-07 | Gilead Sciences, Inc. | Tank-binding kinase inhibitor compounds | 
| EP3423057A1              (en) | 2016-03-04 | 2019-01-09 | Gilead Sciences, Inc. | Compositions and combinations of autotaxin inhibitors | 
| WO2017177179A1              (en) | 2016-04-08 | 2017-10-12 | Gilead Sciences, Inc. | Compositions and methods for treating cancer, inflammatory diseases and autoimmune diseases | 
| JP6730466B2              (ja) | 2016-06-13 | 2020-07-29 | アイ−エムエービー バイオファーマ ユーエス リミテッド | 抗pd−l1抗体およびその使用 | 
| AU2017305303B2              (en) | 2016-08-04 | 2020-05-28 | Gilead Sciences, Inc. | Cobicistat for use in cancer treatments | 
| CA3035346A1              (en) | 2016-09-02 | 2018-03-08 | Gilead Sciences, Inc. | Toll like receptor modulator compounds | 
| WO2018045150A1              (en) | 2016-09-02 | 2018-03-08 | Gilead Sciences, Inc. | 4,6-diamino-pyrido[3,2-d]pyrimidine derivaties as toll like receptor modulators | 
| US20180133212A1              (en) | 2016-11-03 | 2018-05-17 | Gilead Sciences, Inc. | Combination of a bcl-2 inhibitor and a bromodomain inhibitor for treating cancer | 
| US20180133203A1              (en) | 2016-11-11 | 2018-05-17 | Gilead Sciences, Inc. | Methods of treating liver disease | 
| US20180141939A1              (en) | 2016-11-22 | 2018-05-24 | Gilead Sciences, Inc. | Solid forms of a bet inhibitor | 
| AR110252A1              (es) | 2016-11-30 | 2019-03-13 | Gilead Sciences Inc | Compuestos heterocíclicos fusionados como inhibidores de la quinasa cam | 
| CN109071448B              (zh)* | 2017-01-22 | 2020-03-17 | 福建广生堂药业股份有限公司 | Ask1抑制剂及其制备方法和应用 | 
| PL3572412T3              (pl)* | 2017-01-22 | 2021-09-27 | Fujian Cosunter Pharmaceutical Co., Ltd. | Pochodna pirydyny jako inhibitor ask1 oraz sposób jej wytwarzania oraz zastosowanie | 
| PL3383916T3              (pl) | 2017-01-24 | 2023-06-12 | I-Mab Biopharma Us Limited | Przeciwciała anty-cd73 i ich zastosowania | 
| JP2020508326A              (ja) | 2017-02-24 | 2020-03-19 | ギリアド サイエンシズ, インコーポレイテッド | ブルトン型チロシンキナーゼの阻害剤 | 
| TWI754011B              (zh) | 2017-02-24 | 2022-02-01 | 美商基利科學股份有限公司 | 布魯頓氏酪胺酸激酶之抑制劑 | 
| WO2018157277A1              (en)* | 2017-02-28 | 2018-09-07 | Eli Lilly And Company | Isoquinolin and naphthydrin compounds | 
| CN111094250B              (zh)* | 2017-03-03 | 2022-11-04 | 江苏豪森药业集团有限公司 | 凋亡信号调节激酶抑制剂及其制备方法和应用 | 
| JOP20180017A1              (ar) | 2017-03-14 | 2019-01-30 | Gilead Sciences Inc | مثبط كيناز منظم لإشارة تلاشي خلايا | 
| WO2018183342A1              (en) | 2017-03-28 | 2018-10-04 | Gilead Sciences, Inc. | Methods of treating liver disease | 
| CN110520125A              (zh) | 2017-04-12 | 2019-11-29 | 吉利德科学公司 | 治疗肝病的方法 | 
| JOP20180040A1              (ar) | 2017-04-20 | 2019-01-30 | Gilead Sciences Inc | مثبطات pd-1/pd-l1 | 
| AU2018266911C1              (en) | 2017-05-12 | 2022-10-20 | Enanta Pharmaceuticals, Inc. | Apoptosis signal-regulating kinase 1 inhibitors and methods of use thereof | 
| US10450301B2              (en) | 2017-05-25 | 2019-10-22 | Enanta Pharmaceuticals, Inc. | Apoptosis signal-regulating kinase 1 inhibitors and methods of use thereof | 
| WO2018218044A2              (en)* | 2017-05-25 | 2018-11-29 | Enanta Pharmaceuticals Inc | Apoptosis signal-regulating kinase 1 inhibitors and methods of use thereof | 
| WO2018218042A1              (en)* | 2017-05-25 | 2018-11-29 | Enanta Pharmaceuticals, Inc. | Apoptosis signal-regulating kinase 1 inhibitors and methods of use thereof | 
| US10495648B2              (en) | 2017-06-13 | 2019-12-03 | Gilead Sciences, Inc. | Methods of treating liver fibrosis | 
| TW201908306A              (zh)* | 2017-07-18 | 2019-03-01 | 大陸商南京聖和藥業股份有限公司 | 作為ask抑制劑的雜環化合物及其應用 | 
| US10597382B2              (en) | 2017-08-28 | 2020-03-24 | Enanta Pharmaceuticals, Inc. | Tetrazole containing apoptosis signal-regulating kinase 1 inhibitors and methods of use thereof | 
| CN109456308B              (zh)* | 2017-09-06 | 2022-11-29 | 南京圣和药业股份有限公司 | 作为ask抑制剂的杂环化合物及其应用 | 
| US10370352B2              (en) | 2017-09-07 | 2019-08-06 | Eli Lilly And Company | Cyclobutyl-imidazolidinone compounds | 
| WO2019047094A1              (en)* | 2017-09-07 | 2019-03-14 | Eli Lilly And Company | CYCLOBUTYL-IMIDAZOLIDINONE COMPOUNDS | 
| WO2019047161A1              (en) | 2017-09-08 | 2019-03-14 | Eli Lilly And Company | IMIDAZOLIDINE COMPOUNDS | 
| EP3678662A4              (en) | 2017-09-08 | 2021-09-01 | Fronthera U.S. Pharmaceuticals LLC | APOPTOSIS SIGNAL REGULATION KINASE INHIBITORS AND THEIR USES | 
| WO2019072130A1              (zh)* | 2017-10-12 | 2019-04-18 | 深圳市塔吉瑞生物医药有限公司 | 一种1,2,4-三氮唑类化合物 | 
| CN107793400B              (zh)* | 2017-10-31 | 2020-01-31 | 武汉九州钰民医药科技有限公司 | 吡啶类化合物及其在制备治疗肝脏疾病的药物中的应用 | 
| US20200340060A1              (en) | 2017-11-13 | 2020-10-29 | Gilead Sciences, Inc. | Compositions and methods for identifying and treating liver diseases and monitoring treatment outcomes | 
| KR102492187B1              (ko) | 2017-12-20 | 2023-01-27 | 인스티튜트 오브 오가닉 케미스트리 앤드 바이오케미스트리  에이에스 씨알 브이.브이.아이. | Sting 어댑터 단백질을 활성화하는 포스포네이트 결합을 가진 3'3' 사이클릭 다이뉴클레오티드 | 
| US11203610B2              (en) | 2017-12-20 | 2021-12-21 | Institute Of Organic Chemistry And Biochemistry Ascr, V.V.I. | 2′3′ cyclic dinucleotides with phosphonate bond activating the sting adaptor protein | 
| CN111801314B              (zh) | 2018-01-02 | 2023-10-31 | 西尔洛克治疗公司 | Ask1抑制剂化合物及其用途 | 
| EP4227302A1              (en) | 2018-02-13 | 2023-08-16 | Gilead Sciences, Inc. | Pd-1/pd-l1 inhibitors | 
| CN110294742B              (zh)* | 2018-03-21 | 2023-01-31 | 山东轩竹医药科技有限公司 | 并环类ask1抑制剂及其应用 | 
| TWI833744B              (zh) | 2018-04-06 | 2024-03-01 | 捷克科學院有機化學與生物化學研究所 | 3'3'-環二核苷酸 | 
| TW202005654A              (zh) | 2018-04-06 | 2020-02-01 | 捷克科學院有機化學與生物化學研究所 | 2,2,─環二核苷酸 | 
| TWI818007B              (zh) | 2018-04-06 | 2023-10-11 | 捷克科學院有機化學與生物化學研究所 | 2'3'-環二核苷酸 | 
| EP4537902A3              (en)* | 2018-04-12 | 2025-06-11 | Terns, Inc. | Tricyclic ask1 inhibitors | 
| CN112041311B              (zh) | 2018-04-19 | 2023-10-03 | 吉利德科学公司 | Pd-1/pd-l1抑制剂 | 
| CN110407806B              (zh)* | 2018-04-28 | 2021-08-17 | 深圳微芯生物科技股份有限公司 | 甲酰胺类化合物、其制备方法及其应用 | 
| US10683289B2              (en) | 2018-05-02 | 2020-06-16 | Enanta Pharmaceuticals, Inc. | Apoptosis signal-regulating kinase 1 inhibitors and methods of use thereof | 
| JP7328254B2              (ja) | 2018-05-02 | 2023-08-16 | エナンタ ファーマシューティカルズ インコーポレイテッド | アポトーシスシグナル調節キナーゼ1阻害剤を含むテトラゾール及びその使用方法 | 
| TW202014193A              (zh) | 2018-05-03 | 2020-04-16 | 捷克科學院有機化學與生物化學研究所 | 包含碳環核苷酸之2’3’-環二核苷酸 | 
| WO2019217780A1              (en) | 2018-05-11 | 2019-11-14 | Phosphorex, Inc. | Microparticles and nanoparticles having negative surface charges | 
| KR102551319B1              (ko) | 2018-05-14 | 2023-07-05 | 길리애드 사이언시즈, 인코포레이티드 | Mcl-1 억제제 | 
| WO2020006429A1              (en)* | 2018-06-28 | 2020-01-02 | Hepatikos Therapeutics, Llc | Ask1 isoindolin-1-one inhibitors and methods of use thereof | 
| CA3103286C              (en) | 2018-07-13 | 2023-05-09 | Gilead Sciences, Inc. | Pd-1/pd-l1 inhibitors | 
| EP3825315B1              (en)* | 2018-07-20 | 2022-08-31 | Fujian Akeylink Biotechnology Co., Ltd. | Crystal form as ask1 inhibitor, preparation method therefor, and application thereof | 
| WO2020041417A1              (en) | 2018-08-22 | 2020-02-27 | Enanta Pharmaceuticals, Inc. | Cycloalkyl-containing apoptosis signal-regulating kinase 1 inhibitors and methods of use thereof | 
| WO2020072656A1              (en) | 2018-10-03 | 2020-04-09 | Gilead Sciences, Inc. | Imidozopyrimidine derivatives | 
| KR102298546B1              (ko) | 2018-10-18 | 2021-09-08 | 에이치케이이노엔 주식회사 | 신규한 n-(이소프로필-트리아졸릴)피리디닐)-헤테로아릴-카르복사미드 유도체 및 이의 용도 | 
| CN112955435B              (zh) | 2018-10-24 | 2024-09-06 | 吉利德科学公司 | Pd-1/pd-l1抑制剂 | 
| JP7273172B2              (ja) | 2018-10-31 | 2023-05-12 | ギリアード サイエンシーズ, インコーポレイテッド | Hpk1阻害活性を有する置換6-アザベンゾイミダゾール化合物 | 
| DK3873903T3              (da) | 2018-10-31 | 2024-04-02 | Gilead Sciences Inc | Substituerede 6-azabenzimidazolforbindelser som hpk1-hæmmere | 
| CN111170995A              (zh)* | 2018-11-09 | 2020-05-19 | 山东轩竹医药科技有限公司 | Ask1抑制剂及其应用 | 
| WO2020106707A1              (en) | 2018-11-19 | 2020-05-28 | Enanta Pharmaceuticals, Inc. | Apoptosis signal-regulating kinase 1 inhibitors and methods of use thereof | 
| CN109608441A              (zh)* | 2018-12-26 | 2019-04-12 | 都创(上海)医药科技有限公司 | 一种ask1抑制剂的合成工艺 | 
| SG11202107434PA              (en) | 2019-01-15 | 2021-08-30 | Gilead Sciences Inc | Fxr (nr1h4) modulating compounds | 
| CN109813915A              (zh)* | 2019-02-15 | 2019-05-28 | 浠思(上海)生物技术有限公司 | 利用htrf一步法筛选激酶抑制剂的方法 | 
| CN113439078B              (zh) | 2019-02-19 | 2024-04-23 | 吉利德科学公司 | Fxr激动剂的固体形式 | 
| AU2020231115B2              (en) | 2019-03-07 | 2025-02-20 | Institute Of Organic Chemistry And Biochemistry Ascr, V.V.I. | 3'3'-cyclic dinucleotides and prodrugs thereof | 
| WO2020178769A1              (en) | 2019-03-07 | 2020-09-10 | Institute Of Organic Chemistry And Biochemistry Ascr, V.V.I. | 2'3'-cyclic dinucleotides and prodrugs thereof | 
| US11766447B2              (en) | 2019-03-07 | 2023-09-26 | Institute Of Organic Chemistry And Biochemistry Ascr, V.V.I. | 3′3′-cyclic dinucleotide analogue comprising a cyclopentanyl modified nucleotide as sting modulator | 
| US20200315972A1              (en) | 2019-03-11 | 2020-10-08 | Gilead Sciences, Inc. | Formulations of a compound and uses thereof | 
| US11466033B2              (en) | 2019-03-25 | 2022-10-11 | Enanta Pharmaceuticals, Inc. | Substituted pyridines as apoptosis signal-regulating kinase 1 inhibitors | 
| TW202212339A              (zh) | 2019-04-17 | 2022-04-01 | 美商基利科學股份有限公司 | 類鐸受體調節劑之固體形式 | 
| TWI751516B              (zh) | 2019-04-17 | 2022-01-01 | 美商基利科學股份有限公司 | 類鐸受體調節劑之固體形式 | 
| TWI826690B              (zh) | 2019-05-23 | 2023-12-21 | 美商基利科學股份有限公司 | 經取代之烯吲哚酮化物及其用途 | 
| TWI770527B              (zh) | 2019-06-14 | 2022-07-11 | 美商基利科學股份有限公司 | Cot 調節劑及其使用方法 | 
| US20220305115A1              (en) | 2019-06-18 | 2022-09-29 | Janssen Sciences Ireland Unlimited Company | Combination of hepatitis b virus (hbv) vaccines and pyridopyrimidine derivatives | 
| CR20210687A              (es) | 2019-06-25 | 2022-03-03 | Gilead Sciences Inc | PROTEÍNAS DE FUSIÓN FLT3L-Fc Y MÉTODOS DE USO | 
| WO2020261294A1              (en)* | 2019-06-26 | 2020-12-30 | Mankind Pharma Ltd. | Novel apoptosis signal-regulating kinase 1 inhibitors | 
| AR119594A1              (es) | 2019-08-09 | 2021-12-29 | Gilead Sciences Inc | Derivados de tienopirimidina como inhibidores acc y usos de los mismos | 
| EP4045083B1              (en) | 2019-10-18 | 2024-01-10 | Forty Seven, Inc. | Combination therapies for treating myelodysplastic syndromes and acute myeloid leukemia | 
| JP2022552748A              (ja) | 2019-10-31 | 2022-12-19 | フォーティ セブン, インコーポレイテッド | 抗cd47及び抗cd20による血液癌の治療 | 
| TWI778443B              (zh) | 2019-11-12 | 2022-09-21 | 美商基利科學股份有限公司 | Mcl1抑制劑 | 
| CA3158743A1              (en) | 2019-11-15 | 2021-05-20 | Gilead Sciences, Inc. | Triazole carbamate pyridyl sulfonamides as lpa receptor antagonists and uses thereof | 
| CN111018831B              (zh)* | 2019-11-21 | 2022-05-31 | 中国药科大学 | 细胞凋亡信号调节激酶抑制剂及其应用 | 
| US20230105984A1              (en) | 2019-12-23 | 2023-04-06 | Svetlana Marukian | Compositions and methods for the treatment of liver diseases and disorders | 
| PT4081305T              (pt) | 2019-12-24 | 2024-12-04 | Gilead Sciences Inc | Compostos moduladores da diacilglicerol quinase | 
| CA3169451A1              (en) | 2020-02-14 | 2021-08-19 | Jounce Therapeutics, Inc. | Antibodies and fusion proteins that bind to ccr8 and uses thereof | 
| US11655237B2              (en) | 2020-03-30 | 2023-05-23 | Gilead Sciences, Inc. | Solid forms of a Cot inhibitor compound | 
| CN119390681A              (zh) | 2020-04-02 | 2025-02-07 | 吉利德科学公司 | 用于制备cot抑制剂化合物的方法 | 
| CN115698009B              (zh) | 2020-05-01 | 2025-04-08 | 吉利德科学公司 | 抑制cd73的2,4-二氧代嘧啶化合物 | 
| WO2021247215A1              (en) | 2020-06-03 | 2021-12-09 | Gilead Sciences, Inc. | Lpa receptor antagonists and uses thereof | 
| CN113831323B              (zh)* | 2020-06-24 | 2025-08-29 | 武汉人福创新药物研发中心有限公司 | 芳杂环酰胺类化合物及其用途 | 
| CN111808079A              (zh)* | 2020-08-05 | 2020-10-23 | 中国药科大学 | 吲哚类ask1小分子抑制剂及其制备方法和应用 | 
| CN114470217B              (zh)* | 2020-11-24 | 2023-06-20 | 深圳微芯生物科技股份有限公司 | 预防和治疗代谢异常或炎症引起的组织损伤的药物组合物 | 
| EP4304711A1              (en) | 2021-03-11 | 2024-01-17 | Gilead Sciences, Inc. | Glp-1r modulating compounds | 
| US12410160B2              (en) | 2021-03-29 | 2025-09-09 | Gilead Sciences, Inc. | KHK inhibitors | 
| TW202302145A              (zh) | 2021-04-14 | 2023-01-16 | 美商基利科學股份有限公司 | CD47/SIRPα結合及NEDD8活化酶E1調節次單元之共抑制以用於治療癌症 | 
| CN114246866B              (zh)* | 2021-04-28 | 2023-09-12 | 深圳微芯生物科技股份有限公司 | 用于治疗慢性肾病的药物及其用途 | 
| JP7701473B2              (ja) | 2021-05-11 | 2025-07-01 | ギリアード サイエンシーズ, インコーポレイテッド | Lpa受容体アンタゴニスト及びそれらの使用 | 
| US20220411406A1              (en) | 2021-05-13 | 2022-12-29 | Gilead Sciences, Inc. | Lpa receptor antagonists and uses thereof | 
| WO2022245671A1              (en) | 2021-05-18 | 2022-11-24 | Gilead Sciences, Inc. | Methods of using flt3l-fc fusion proteins | 
| TW202345826A              (zh) | 2021-06-04 | 2023-12-01 | 美商基利科學股份有限公司 | 治療nash之方法 | 
| TW202311256A              (zh) | 2021-06-18 | 2023-03-16 | 美商基利科學股份有限公司 | 用於治療fxr誘發之搔癢之il-31調節劑 | 
| JP7654118B2              (ja) | 2021-06-23 | 2025-03-31 | ギリアード サイエンシーズ, インコーポレイテッド | ジアシルグリセロールキナーゼ調節化合物 | 
| JP7651018B2              (ja) | 2021-06-23 | 2025-03-25 | ギリアード サイエンシーズ, インコーポレイテッド | ジアシルグリセロールキナーゼ調節化合物 | 
| EP4359413A1              (en) | 2021-06-23 | 2024-05-01 | Gilead Sciences, Inc. | Diacylglyercol kinase modulating compounds | 
| WO2022271677A1              (en) | 2021-06-23 | 2022-12-29 | Gilead Sciences, Inc. | Diacylglyercol kinase modulating compounds | 
| TWI857377B              (zh) | 2021-10-28 | 2024-10-01 | 美商基利科學股份有限公司 | 嗒-3(2h)-酮衍生物 | 
| EP4422756A1              (en) | 2021-10-29 | 2024-09-04 | Gilead Sciences, Inc. | Cd73 compounds | 
| US20230220106A1              (en) | 2021-12-08 | 2023-07-13 | Dragonfly Therapeutics, Inc. | Antibodies targeting 5t4 and uses thereof | 
| JP7709612B2              (ja) | 2021-12-08 | 2025-07-16 | ギリアード サイエンシーズ, インコーポレイテッド | Lpa受容体アンタゴニスト及びそれらの使用 | 
| US20230203202A1              (en) | 2021-12-08 | 2023-06-29 | Dragonfly Therapeutics, Inc. | Proteins binding nkg2d, cd16 and 5t4 | 
| JP2024546851A              (ja) | 2021-12-22 | 2024-12-26 | ギリアード サイエンシーズ, インコーポレイテッド | Ikarosジンクフィンガーファミリー分解剤及びその使用 | 
| EP4452415A1              (en) | 2021-12-22 | 2024-10-30 | Gilead Sciences, Inc. | Ikaros zinc finger family degraders and uses thereof | 
| TW202340168A              (zh) | 2022-01-28 | 2023-10-16 | 美商基利科學股份有限公司 | Parp7抑制劑 | 
| PE20242225A1              (es) | 2022-03-17 | 2024-11-19 | Gilead Sciences Inc | Degradadores de dedos de zinc de la familia ikaros y usos de estos | 
| US20230355796A1              (en) | 2022-03-24 | 2023-11-09 | Gilead Sciences, Inc. | Combination therapy for treating trop-2 expressing cancers | 
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| EP4547657A1              (en) | 2022-07-01 | 2025-05-07 | Gilead Sciences, Inc. | Cd73 compounds | 
| US20240091351A1              (en) | 2022-09-21 | 2024-03-21 | Gilead Sciences, Inc. | FOCAL IONIZING RADIATION AND CD47/SIRPa DISRUPTION ANTICANCER COMBINATION THERAPY | 
| KR20250122479A              (ko) | 2022-12-22 | 2025-08-13 | 길리애드 사이언시즈, 인코포레이티드 | Prmt5 억제제 및 이의 용도 | 
| CN115844887B              (zh)* | 2022-12-28 | 2023-09-08 | 中国人民解放军空军军医大学 | Selonsertib在制备治疗癌症的药物中的用途 | 
| WO2024215754A1              (en) | 2023-04-11 | 2024-10-17 | Gilead Sciences, Inc. | Kras modulating compounds | 
| WO2024220917A1              (en) | 2023-04-21 | 2024-10-24 | Gilead Sciences, Inc. | Prmt5 inhibitors and uses thereof | 
| WO2024236595A1              (en)* | 2023-05-18 | 2024-11-21 | Council Of Scientific And Industrial Research | Protacs for ask1 protein degradation: preparation and use thereof | 
| US20250042922A1              (en) | 2023-06-30 | 2025-02-06 | Gilead Sciences, Inc. | Kras modulating compounds | 
| US20250100998A1              (en) | 2023-07-26 | 2025-03-27 | Gilead Sciences, Inc. | Parp7 inhibitors | 
| US20250066328A1              (en) | 2023-07-26 | 2025-02-27 | Gilead Sciences, Inc. | Parp7 inhibitors | 
| US20250101042A1              (en) | 2023-09-08 | 2025-03-27 | Gilead Sciences, Inc. | Kras g12d modulating compounds | 
| WO2025054530A1              (en) | 2023-09-08 | 2025-03-13 | Gilead Sciences, Inc. | Pyrimidine-containing polycyclic derivatives as kras g12d modulating compounds | 
| US20250154172A1              (en) | 2023-11-03 | 2025-05-15 | Gilead Sciences, Inc. | Prmt5 inhibitors and uses thereof | 
| US20250230168A1              (en) | 2023-12-22 | 2025-07-17 | Gilead Sciences, Inc. | Azaspiro wrn inhibitors |