Movatterモバイル変換

[0]ホーム
URL:

MX2013014398A - Heterocyclic sulfonamide derivatives. - Google Patents

Heterocyclic sulfonamide derivatives.

Info

Publication number
MX2013014398A
MX2013014398AMX2013014398AMX2013014398AMX2013014398AMX 2013014398 AMX2013014398 AMX 2013014398AMX 2013014398 AMX2013014398 AMX 2013014398AMX 2013014398 AMX2013014398 AMX 2013014398AMX 2013014398 AMX2013014398 AMX 2013014398A
Authority
MX
Mexico
Prior art keywords
sulfonamide derivatives
heterocyclic sulfonamide
compounds
heterocyclic
mek
Prior art date
Application number
MX2013014398A
Other languages
Spanish (es)
Inventor
Ramulu Poddutoori
Can Wang
Xianglin Zhao
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis AgfiledCriticalNovartis Ag
Publication of MX2013014398ApublicationCriticalpatent/MX2013014398A/en

Links

Classifications

Landscapes

Abstract

The present invention relates to compounds (I) and pharmaceutically acceptable salts thereof. The compounds have been demonstrated as inhibitors of MEK and therefore may be useful in the treatment of hyperproliferative diseases like cancer and inflammation.
MX2013014398A2011-06-092012-06-06Heterocyclic sulfonamide derivatives.MX2013014398A (en)

Applications Claiming Priority (3)

Application NumberPriority DateFiling DateTitle
IN1634DE20112011-06-09
CN2012101751452012-05-31
PCT/IB2012/052860WO2012168884A1 (en)2011-06-092012-06-06Heterocyclic sulfonamide derivatives

Publications (1)

Publication NumberPublication Date
MX2013014398Atrue MX2013014398A (en)2014-03-21

Family

ID=46384435

Family Applications (1)

Application NumberTitlePriority DateFiling Date
MX2013014398AMX2013014398A (en)2011-06-092012-06-06Heterocyclic sulfonamide derivatives.

Country Status (10)

CountryLink
EP (1)EP2718276A1 (en)
JP (1)JP2014517004A (en)
KR (1)KR20140034898A (en)
AU (1)AU2012265844A1 (en)
BR (1)BR112013031201A2 (en)
CA (1)CA2838029A1 (en)
EA (1)EA201391820A1 (en)
IN (1)IN2014DN00123A (en)
MX (1)MX2013014398A (en)
WO (1)WO2012168884A1 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication numberPriority datePublication dateAssigneeTitle
JPWO2013094546A1 (en)*2011-12-192015-04-27住友化学株式会社 Method for producing sulfonate
EP3251673A1 (en)2012-12-132017-12-06IP Gesellschaft für Management mbHCombination therapy comprising a cdk4/6 inhibitor and a pi3k inhibitor for use in the treatment of cancer
CN104886052B (en)*2015-06-022016-08-31吉林省八达农药有限公司A kind of application of cyclopropyl-sulfonylamide
CN110869357A (en)*2017-05-252020-03-06亚瑞克西斯制药公司Compounds and methods of use thereof for treating cancer
WO2019183385A1 (en)*2018-03-222019-09-26University Of RochesterMapk/erk inhibition for ovarian and other cancers

Family Cites Families (52)

* Cited by examiner, † Cited by third party
Publication numberPriority datePublication dateAssigneeTitle
FR901228A (en)1943-01-161945-07-20Deutsche Edelstahlwerke Ag Ring gap magnet system
GB1524747A (en)1976-05-111978-09-13Ici LtdPolypeptide
LU88769I2 (en)1982-07-231996-11-05Zeneca Ltd Bicalutamide and its pharmaceutically acceptable salts and esters (Casodex (R))
GB8327256D0 (en)1983-10-121983-11-16Ici PlcSteroid derivatives
US5093330A (en)1987-06-151992-03-03Ciba-Geigy CorporationStaurosporine derivatives substituted at methylamino nitrogen
US5010099A (en)1989-08-111991-04-23Harbor Branch Oceanographic Institution, Inc.Discodermolide compounds, compositions containing same and method of preparation and use
US5395855A (en)1990-05-071995-03-07Ciba-Geigy CorporationHydrazones
NZ243082A (en)1991-06-281995-02-24Ici Plc4-anilino-quinazoline derivatives; pharmaceutical compositions, preparatory processes, and use thereof
GB9300059D0 (en)1992-01-201993-03-03Zeneca LtdQuinazoline derivatives
TW225528B (en)1992-04-031994-06-21Ciba Geigy Ag
ATE215565T1 (en)1992-10-282002-04-15Genentech Inc USE OF ANTI-VEGF ANTIBODIES TO TREAT CANCER
GB9314893D0 (en)1993-07-191993-09-01Zeneca LtdQuinazoline derivatives
WO1996030347A1 (en)1995-03-301996-10-03Pfizer Inc.Quinazoline derivatives
GB9508538D0 (en)1995-04-271995-06-14Zeneca LtdQuinazoline derivatives
US5747498A (en)1996-05-281998-05-05Pfizer Inc.Alkynyl and azido-substituted 4-anilinoquinazolines
US5880141A (en)1995-06-071999-03-09Sugen, Inc.Benzylidene-Z-indoline compounds for the treatment of disease
US5843901A (en)1995-06-071998-12-01Advanced Research & Technology InstituteLHRH antagonist peptides
SI9620103A (en)1995-07-061998-10-31Novartis AgPyrrolopyrimidines and processes for the preparation thereof
US5760041A (en)1996-02-051998-06-02American Cyanamid Company4-aminoquinazoline EGFR Inhibitors
GB9603095D0 (en)1996-02-141996-04-10Zeneca LtdQuinazoline derivatives
JP3370340B2 (en)1996-04-122003-01-27ワーナー―ランバート・コンパニー Irreversible inhibitors of tyrosine kinase
AU2912997A (en)1996-06-241998-01-14Pfizer Inc.Phenylamino-substituted tricyclic derivatives for treatment of hyperproliferative diseases
JP2001500851A (en)1996-08-302001-01-23ノバルティス アクチエンゲゼルシャフト Process for producing epothilone and intermediate products obtained during the process
EP0938597B1 (en)1996-09-062003-08-20Obducat AktiebolagMethod for anisotropic etching of structures in conducting materials
DE19638745C2 (en)1996-09-112001-05-10Schering Ag Monoclonal antibodies against the extracellular domain of the human VEGF receptor protein (KDR)
WO1998010767A2 (en)1996-09-131998-03-19Sugen, Inc.Use of quinazoline derivatives for the manufacture of a medicament in the treatment of hyperproliferative skin disorders
EP0837063A1 (en)1996-10-171998-04-22Pfizer Inc.4-Aminoquinazoline derivatives
ES2312695T3 (en)1996-11-182009-03-01Gesellschaft Fur Biotechnologische Forschung Mbh (Gbf) EPOTILONES E AND F.
US6441186B1 (en)1996-12-132002-08-27The Scripps Research InstituteEpothilone analogs
CO4950519A1 (en)1997-02-132000-09-01Novartis Ag PHTHALAZINES, PHARMACEUTICAL PREPARATIONS THAT UNDERSTAND THEM AND THE PROCESS FOR THEIR PREPARATION
CO4940418A1 (en)1997-07-182000-07-24Novartis Ag MODIFICATION OF A CRYSTAL OF A DERIVATIVE OF N-PHENYL-2-PIRIMIDINAMINE, PROCESSES FOR ITS MANUFACTURE AND USE
GB9721069D0 (en)1997-10-031997-12-03Pharmacia & Upjohn SpaPolymeric derivatives of camptothecin
US6194181B1 (en)1998-02-192001-02-27Novartis AgFermentative preparation process for and crystal forms of cytostatics
MXPA00008365A (en)1998-02-252002-11-07Sloan Kettering Inst CancerSynthesis of epothilones, intermediates thereto and analogues therof.
BR9912938B1 (en)1998-08-112011-06-28 isoquinoline derivatives, composition comprising them, process for preparation and use thereof.
GB9824579D0 (en)1998-11-101999-01-06Novartis AgOrganic compounds
UA71587C2 (en)1998-11-102004-12-15Шерінг АкцієнгезелльшафтAnthranilic acid amides and use thereof as medicaments
JP4662635B2 (en)1998-11-202011-03-30コーサン バイオサイエンシーズ， インコーポレイテッド Recombinant methods and materials for producing epothilone and epothilone derivatives
WO2000037502A2 (en)1998-12-222000-06-29Genentech, Inc.Vascular endothelial cell growth factor antagonists and uses thereof
ES2265929T3 (en)1999-03-302007-03-01Novartis Ag FTALAZINE DERIVATIVES FOR THE TREATMENT OF INFLAMMATORY DISEASES.
PE20020354A1 (en)2000-09-012002-06-12Novartis Ag HYDROXAMATE COMPOUNDS AS HISTONE-DESACETILASE (HDA) INHIBITORS
TWI238824B (en)2001-05-142005-09-01Novartis Ag4-amino-5-phenyl-7-cyclobutyl-pyrrolo[2,3-d]pyrimidine derivatives
GB0119249D0 (en)2001-08-072001-10-03Novartis AgOrganic compounds
JP2006083137A (en)*2004-09-172006-03-30Sankyo Co LtdImmunosuppressive agent
US8648116B2 (en)*2005-07-212014-02-11Ardea Biosciences, Inc.Derivatives of N-(arylamino) sulfonamides including polymorphs as inhibitors of MEK as well as compositions, methods of use and methods for preparing the same
ES2547303T3 (en)*2007-01-192015-10-05Ardea Biosciences, Inc. MEK inhibitors
WO2009112490A1 (en)*2008-03-112009-09-17Cellzome LimitedSulfonamides as zap-70 inhibitors
PE20110570A1 (en)*2008-07-012011-08-26Genentech Inc REPLACED BICYCLE HETEROCYCLES
MX2011011083A (en)*2009-04-212011-11-04Novartis AgHeterocyclic compounds as mek inhibitors.
CN102134218A (en)*2009-06-152011-07-27凯美隆(北京)药业技术有限公司6-aryl amino pyridone sulfamide and 6-aryl amino pymetrozine sulfamide methyl ethyl ketone (MEK) inihibitor
PE20121471A1 (en)*2009-11-042012-11-01Novartis Ag HELPFUL HETEROCYCLIC SULFONAMIDE DERIVATIVES AS MEK INHIBITORS
KR20120102750A (en)*2009-12-082012-09-18노파르티스 아게Heterocyclic sulfonamide derivatives

Also Published As

Publication numberPublication date
WO2012168884A1 (en)2012-12-13
CA2838029A1 (en)2012-12-13
IN2014DN00123A (en)2015-05-22
JP2014517004A (en)2014-07-17
EP2718276A1 (en)2014-04-16
BR112013031201A2 (en)2017-01-31
KR20140034898A (en)2014-03-20
EA201391820A1 (en)2014-12-30
AU2012265844A1 (en)2013-05-02

Similar Documents

PublicationPublication DateTitle
CY1122266T1 (en) 3-AMINOCYCLALKYL COMPOUNDS AS ROR-GAMMA-T INHIBITORS AND USES THEREOF
AU2012214029A8 (en)Rorgammat inhibitors
MX2011011083A (en)Heterocyclic compounds as mek inhibitors.
PH12016500024A1 (en)Bromodomain inhibitor
SA515360469B1 (en)Heterocyclic compounds for inhibiting glutaminase and their methods of use
IN2015DN01156A (en)
WO2014028591A3 (en)N-ALKYLATED INDOLE AND INDAZOLE COMPOUNDS AS RORgammaT INHIBITORS AND USES THEREOF
IN2014MN01755A (en)
EP4233869A3 (en)Use of pyrazolopyrimidine derivatives for the treatment of pi3k related disorders
EA201200651A1 (en) HETEROCYCLIC SULPHONAMIDE DERIVATIVES APPLICABLE AS MEK INHIBITORS
UA111382C2 (en)Protein kinase inhibitors
MX360634B (en)Substituted 3-haloallylamine inhibitors of ssao and uses thereof.
IN2014KN00769A (en)
PH12015501024A1 (en)Bendamustine derivatives and methods of using same
MX2013012977A (en)Thiazole derivatives.
IN2015DN01119A (en)
PH12013501591A1 (en)Il17 and ifn-gamma inhibition for the treatment of autoimmune inflammation
PH12013501574A1 (en)Il17 and ifn-gamma inhibition for the treatment of autoimmune inflammation
MX2014003376A (en)Benzoic acid derivatives as eif4e inhibitors.
IN2015DN01151A (en)
EA032271B9 (en)Compounds, pharmaceutical composition and methods for use in treating inflammatory diseases
TN2012000242A1 (en)Heterocyclic sulfonamide derivatives
MX2013014398A (en)Heterocyclic sulfonamide derivatives.
IN2014DN08443A (en)
AU2012307449A8 (en)Sulfonic acid salts of heterocyclylamide-substituted imidazoles
[8]ページ先頭
©2009-2025 Movatter.jp