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MX2013003179A - 2' -fluoro substituted carba-nucleoside analogs for antiviral treatment. - Google Patents

2' -fluoro substituted carba-nucleoside analogs for antiviral treatment.

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Publication number
MX2013003179A
MX2013003179AMX2013003179AMX2013003179AMX2013003179AMX 2013003179 AMX2013003179 AMX 2013003179AMX 2013003179 AMX2013003179 AMX 2013003179AMX 2013003179 AMX2013003179 AMX 2013003179AMX 2013003179 AMX2013003179 AMX 2013003179A
Authority
MX
Mexico
Prior art keywords
nucleoside analogs
fluoro substituted
antiviral treatment
nucleoside
substituted carba
Prior art date
Application number
MX2013003179A
Other languages
Spanish (es)
Inventor
Aesop Cho
Choung Kim
Adrian Ray
Original Assignee
Gilead Sciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filedlitigationCriticalhttps://patents.darts-ip.com/?family=47748238&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2013003179(A)"Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US12/885,917external-prioritypatent/US7973013B2/en
Priority claimed from US13/050,820external-prioritypatent/US8455451B2/en
Application filed by Gilead Sciences IncfiledCriticalGilead Sciences Inc
Publication of MX2013003179ApublicationCriticalpatent/MX2013003179A/en

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Abstract

Translated fromSpanish

Se proporcionan nucleósidos de imidazo[1 ,2-f} [1, 2, 4)triazinilo selectos, fosfatos de nucleósidos, y profármacos de lo mismo, donde la posición 2' del glúcido nucleosídico se sustituye con sustituyentes halógeno y carbono. Los compuestos, composiciones y métodos proporcionados son útiles para el tratamiento de infecciones por virus Flaviviridae, particularmente infecciones por Hepatitis C causadas tanto por cepas de tipo salvaje como mutantes del VHC. Fórmula (I). (Ver Formula).Imidazo [1,2-f} [1,2,4) triazinyl nucleosides, nucleoside phosphates, and prodrugs thereof are provided, where the 2 'position of the nucleoside carbohydrate is substituted with halogen and carbon substituents. The compounds, compositions and methods provided are useful for the treatment of Flaviviridae virus infections, particularly Hepatitis C infections caused by both wild-type strains and HCV mutants. Formula (I). (See Formula).

MX2013003179A2010-09-202011-03-222' -fluoro substituted carba-nucleoside analogs for antiviral treatment.MX2013003179A (en)

Applications Claiming Priority (3)

Application NumberPriority DateFiling DateTitle
US12/885,917US7973013B2 (en)2009-09-212010-09-202'-fluoro substituted carba-nucleoside analogs for antiviral treatment
US13/050,820US8455451B2 (en)2009-09-212011-03-172'-fluoro substituted carba-nucleoside analogs for antiviral treatment
PCT/US2011/029441WO2012039791A1 (en)2010-09-202011-03-222' -fluoro substituted carba-nucleoside analogs for antiviral treatment

Publications (1)

Publication NumberPublication Date
MX2013003179Atrue MX2013003179A (en)2013-04-24

Family

ID=47748238

Family Applications (1)

Application NumberTitlePriority DateFiling Date
MX2013003179AMX2013003179A (en)2010-09-202011-03-222' -fluoro substituted carba-nucleoside analogs for antiviral treatment.

Country Status (22)

CountryLink
EP (1)EP2619206A1 (en)
JP (4)JP2013538230A (en)
KR (1)KR101879887B1 (en)
CN (1)CN103108876A (en)
AP (1)AP3699A (en)
AU (1)AU2011306066B2 (en)
BR (1)BR112013008017A2 (en)
CA (1)CA2807496C (en)
CL (1)CL2013000727A1 (en)
CO (1)CO6680669A2 (en)
CR (1)CR20130172A (en)
EA (1)EA026523B1 (en)
EC (1)ECSP13012560A (en)
IL (1)IL225221A0 (en)
MA (1)MA34593B1 (en)
MX (1)MX2013003179A (en)
NZ (1)NZ608070A (en)
PE (3)PE20171624A1 (en)
PH (1)PH12013500311B1 (en)
SG (1)SG188223A1 (en)
WO (1)WO2012039791A1 (en)
ZA (1)ZA201301042B (en)

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HRP20241620T1 (en)2017-12-072025-01-31Emory University N4-HYDROXYCYTIDINE AND DERIVATIVES AND ANTIVIRAL USE RELATED THERETO
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CR20220675A (en)2020-06-242023-02-15Gilead Sciences Inc1'-cyano nucleoside analogs and uses thereof
HUE067491T2 (en)*2020-08-272024-10-28Gilead Sciences IncCompounds and methods for treatment of viral infections
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Also Published As

Publication numberPublication date
KR101879887B1 (en)2018-07-18
JP2016074732A (en)2016-05-12
JP6475280B2 (en)2019-02-27
BR112013008017A2 (en)2016-06-14
MA34593B1 (en)2013-10-02
EA026523B1 (en)2017-04-28
AU2011306066A1 (en)2013-02-28
CL2013000727A1 (en)2013-08-23
ZA201301042B (en)2014-07-30
EP2619206A1 (en)2013-07-31
CA2807496C (en)2019-01-22
EA201390141A1 (en)2013-09-30
JP2013538230A (en)2013-10-10
SG188223A1 (en)2013-04-30
AP3699A (en)2016-05-31
CA2807496A1 (en)2012-03-29
CN103108876A (en)2013-05-15
AU2011306066B2 (en)2015-01-29
PH12013500311B1 (en)2017-11-08
CO6680669A2 (en)2013-05-31
PE20230684A1 (en)2023-04-21
JP2019014726A (en)2019-01-31
CR20130172A (en)2013-05-29
WO2012039791A1 (en)2012-03-29
AP2013006767A0 (en)2013-03-31
ECSP13012560A (en)2013-06-28
PE20131165A1 (en)2013-10-14
PH12013500311A1 (en)2013-04-22
IL225221A0 (en)2013-06-27
NZ608070A (en)2015-11-27
JP2017119726A (en)2017-07-06
KR20130110168A (en)2013-10-08
PE20171624A1 (en)2017-11-02

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