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KR880001630A - 5-fluorouracil derivatives and uses thereof - Google Patents

5-fluorouracil derivatives and uses thereof
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Publication number
KR880001630A
KR880001630AKR1019870006895AKR870006895AKR880001630AKR 880001630 AKR880001630 AKR 880001630AKR 1019870006895 AKR1019870006895 AKR 1019870006895AKR 870006895 AKR870006895 AKR 870006895AKR 880001630 AKR880001630 AKR 880001630A
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KR
South Korea
Prior art keywords
fluorouracil
fluorouracil derivative
pyridyloxycarbonyl
benzoyloxy
ethoxymethyl
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KR1019870006895A
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Korean (ko)
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KR950011394B1 (en
Inventor
세쓰로 후지이
Original Assignee
오오쓰까 아끼히꼬
오오쓰까세이야꾸 가부시끼가이샤
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Priority claimed from JP61181027Aexternal-prioritypatent/JPS63301880A/en
Priority claimed from JP62034161Aexternal-prioritypatent/JPS63201127A/en
Application filed by 오오쓰까 아끼히꼬, 오오쓰까세이야꾸 가부시끼가이샤filedCritical오오쓰까 아끼히꼬
Publication of KR880001630ApublicationCriticalpatent/KR880001630A/en
Application grantedgrantedCritical
Publication of KR950011394B1publicationCriticalpatent/KR950011394B1/en
Anticipated expirationlegal-statusCritical
Expired - Fee Relatedlegal-statusCriticalCurrent

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Abstract

Translated fromKorean

내용 없음No content

Description

Translated fromKorean
5-플루오로우라실 유도체 및 그의 용도5-fluorouracil derivatives and uses thereof

본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음As this is a public information case, the full text was not included.

Claims (10)

Translated fromKorean
하기 일반식(I)로 표시되는 5-플루오로우라실 유도체.5-Fluorouracil derivatives represented by the following general formula (I).[상기 식중, Ra는 C1~C6알콕시메틸기이다].[Wherein Ra is a C1 to C6 alkoxymethyl group].제1항에 있어서, 5-플루오로우라실 유도체가 3-[3-(6-벤조일옥시-3-시아노-2-피리딜옥시카르보닐)벤조일]-1-에톡시메틸-5-플루오로우라실인 화합물.The compound of claim 1, wherein the 5-fluorouracil derivative is 3- [3- (6-benzoyloxy-3-cyano-2-pyridyloxycarbonyl) benzoyl] -1-ethoxymethyl-5-fluoro A compound that is uracil.하기 일반식(I)로 표시되는 5-플루오로우라실 유도체의 유효량 및 약학적으로 허용 가능한 담체로 구성되는 항암 조성물.An anticancer composition comprising an effective amount of a 5-fluorouracil derivative represented by the following general formula (I) and a pharmaceutically acceptable carrier.[상기 식중, Ra는 C1~C6알콕시메틸기이다].[Wherein Ra is a C1 to C6 alkoxymethyl group].제3항에 있어서, 5-플루오로우라실 유도체가 3-[3-(6-벤조일옥시-3-시아노-2-피리딜옥시카르보닐) 벤조일]-1-에톡시메틸-5-플루오로우라실인 항암 조성물.The 5-fluorouracil derivative according to claim 3, wherein the 5-fluorouracil derivative is 3- [3- (6-benzoyloxy-3-cyano-2-pyridyloxycarbonyl) benzoyl] -1-ethoxymethyl-5-fluoro An anticancer composition that is uracil.하기 일반식(1)로 표시되는 5-플루오로우라실 유도체의 유효량을 환자에게 투여함을 특징으로 하는 환자에 있어서 암의 치료방법.A method for treating cancer in a patient, characterized by administering to the patient an effective amount of the 5-fluorouracil derivative represented by the following general formula (1).[상기 식중, Ra는 C1~C6알콕시메틸기이다].[Wherein Ra is a C1 to C6 alkoxymethyl group].제5항에 있어서, 5-플루오로우라실 유도체가 3-[3-6-벤조일옥시-3-시아노-2-피리딜옥시카르보닐)벤조일]-1-에톡시메틸-5-플루오로우라실인 암의 치료방법.6. The 5-fluorouracil derivative according to claim 5, wherein the 5-fluorouracil derivative is 3- [3-6-benzoyloxy-3-cyano-2-pyridyloxycarbonyl) benzoyl] -1-ethoxymethyl-5-fluorouracil. Method of treatment of phosphorus cancer.암 치료용 조성물을 제조하기 위한 하기 일반식(I)로 표시되는 5-플루오로우라실 유도체의 용도.Use of a 5-fluorouracil derivative represented by the following general formula (I) for preparing a composition for treating cancer.[상기 식중, Ra는 C1~C6알콕시메틸기이다].[Wherein Ra is a C1 to C6 alkoxymethyl group].제7항에 있어서, 5-플루오로우라실 유도체가 3-[3-(6-벤조일옥시-3-시아노-2-피리딜옥시카르보닐)벤조일]-1-에톡시메틸-5-플루오로우라실인 암 치료용 조성물을 제조하기 위한 5-플루오로우라실 유도체의 용도.The method of claim 7, wherein the 5-fluorouracil derivative is 3- [3- (6-benzoyloxy-3-cyano-2-pyridyloxycarbonyl) benzoyl] -1-ethoxymethyl-5-fluoro Use of a 5-fluorouracil derivative for preparing a composition for treating cancer that is uracil.암을 치료하기 위한 하기 일반식(1)로 표시되는 5-플루오로우라실 유도체의 용도.Use of the 5-fluorouracil derivative represented by following General formula (1) for treating cancer.[상기 식중, Ra는 C1~C6알콕시메틸기이다].[Wherein Ra is a C1 to C6 alkoxymethyl group].제9항에 있어서, 5-플루오로우라실 유도체가 3-[3-(6-벤조일옥시-3-시아노-2-피리딜옥시카르보닐)벤조일]-1-에톡시메틸-5-플루오로우라실인 암을 치료하기 위한 5-플루오로우라실 유도체의 용도.10. The process of claim 9, wherein the 5-fluorouracil derivative is 3- [3- (6-benzoyloxy-3-cyano-2-pyridyloxycarbonyl) benzoyl] -1-ethoxymethyl-5-fluoro Use of 5-fluorouracil derivatives for treating cancer that is uracil.※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.※ Note: The disclosure is based on the initial application.
KR1019870006895A1986-07-251987-07-015-fluorouracil depivativesExpired - Fee RelatedKR950011394B1 (en)

Applications Claiming Priority (9)

Application NumberPriority DateFiling DateTitle
JP176464/19861986-07-25
JP86-1764641986-07-25
JP176464861986-07-25
JP86-1810721986-07-30
JP181027/19861986-07-30
JP61181027AJPS63301880A (en)1985-09-031986-07-305-fluorouracil derivative
JP34161/19871987-02-17
JP87-341611987-02-17
JP62034161AJPS63201127A (en)1987-02-171987-02-17Carcinostatic agent containing 5-fluorouracil derivative

Publications (2)

Publication NumberPublication Date
KR880001630Atrue KR880001630A (en)1988-04-25
KR950011394B1 KR950011394B1 (en)1995-10-02

Family

ID=27288338

Family Applications (2)

Application NumberTitlePriority DateFiling Date
KR1019870002961AExpired - Fee RelatedKR950009857B1 (en)1986-07-251987-03-30Process for preparing 5-fluorouracil derivatives
KR1019870006895AExpired - Fee RelatedKR950011394B1 (en)1986-07-251987-07-015-fluorouracil depivatives

Family Applications Before (1)

Application NumberTitlePriority DateFiling Date
KR1019870002961AExpired - Fee RelatedKR950009857B1 (en)1986-07-251987-03-30Process for preparing 5-fluorouracil derivatives

Country Status (10)

CountryLink
KR (2)KR950009857B1 (en)
CH (1)CH671578A5 (en)
DE (1)DE3709699C2 (en)
DK (1)DK169520B1 (en)
ES (1)ES2004904A6 (en)
FR (1)FR2605006B1 (en)
GB (1)GB2192880B (en)
IT (1)IT1207785B (en)
NL (1)NL194043C (en)
SE (1)SE464303B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication numberPriority datePublication dateAssigneeTitle
US4864021A (en)*1984-10-301989-09-05Otsuka Pharmaceutical Co., Ltd.5-fluorouracil derivatives
DE69003670T2 (en)1989-01-051994-01-27Otsuka Pharma Co Ltd NON-INJECTABLE CARCINOSTATIC AGENT FOR PREVENTING INFLAMMATION BY 5-FLUORURACIL AND METHOD FOR TREATING CANCER.
KR0172134B1 (en)*1990-07-191999-02-01오오쓰까 아끼히코Solid preparation
PT2495243T (en)*2009-10-272017-03-13Delta-Fly Pharma IncNovel 5-fluorouracil derivative

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication numberPriority datePublication dateAssigneeTitle
DE3588036T2 (en)*1984-10-301995-11-16Otsuka Pharma Co Ltd 5-fluorouracil derivatives.
JPS61114739A (en)*1984-11-081986-06-02Mitsubishi Rayon Co LtdPreparation of catalyst for preparing unsaturated carboxylic acid

Also Published As

Publication numberPublication date
IT8705150A0 (en)1987-03-30
GB2192880A (en)1988-01-27
GB2192880B (en)1990-05-09
NL8700742A (en)1988-02-16
KR950011394B1 (en)1995-10-02
DK169520B1 (en)1994-11-21
SE464303B (en)1991-04-08
FR2605006A1 (en)1988-04-15
DE3709699A1 (en)1988-02-04
DE3709699C2 (en)1996-09-05
GB8706972D0 (en)1987-04-29
NL194043B (en)2001-01-02
ES2004904A6 (en)1989-02-16
CH671578A5 (en)1989-09-15
IT1207785B (en)1989-06-01
SE8701118D0 (en)1987-03-18
KR880001635A (en)1988-04-25
FR2605006B1 (en)1990-01-12
DK133387A (en)1988-01-26
KR950009857B1 (en)1995-08-29
SE8701118L (en)1988-01-26
DK133387D0 (en)1987-03-16
NL194043C (en)2001-05-03

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