환자 폐 속의 질환이나 이상상태를 분석하는 방법에는 기관지폐포세척세포와 기도점막생검과 같은 방법들이 있었다. 각각의 방법마다 관찰되는 기도의 부위가 다르며 이에 다른 장단점이 있다. 기관지폐포세척세포의 분석은 기도점막생검에 비해 기도조직의 전체적인 변화를 직접 반영하지 못한다는 점이 있으나, 호산구와 호중구의 변화에 관한 경우 이 세포들이 혈액과 기도내강을 수시로 이동할 수 있기 때문에 조직검사보다는 기관지폐포세척액에서 더 정확한 결과를 얻을 수 있다 (Beasley, R., Roche, W.R., Roberts, J.A., Holgate, S.T., 1989. Cellular events in the bronchi in mild asthma and after bronchial provocation. Am. Rev. Respir. Dis. 139 pp806-817). 그러나 전통적으로 폐질환검사에 사용되는 기관지폐포세척과 기도점막생검 같은 샘플링방법은 환자들에게 커다란 부담을 주었다.따라서 검사에 제약이 따랐으며 보다 간편한 샘플링 방법을 요구하게 되었다. 따라서 본 고안에서는 폐호기를 얼음등을 집어넣은 냉각장치에 접촉시켜 온도 차이에 의해 폐호기 응결액이 포집통에 모집되는 장비를 발명하였다. 이렇게 간편하게 수집된 폐호기 응결액을 분석하여 폐의 이상 여부를 쉽게 검사할 수 있다. 한국인에 있어서 폐호기 응결액속의 성분 분석에 의한 폐질환검사는 아직 진행되지 않았다. 이 방법은 앞으로 임상적 폐 이상의 검사, 예측, 진단 및 치료 분야에서 중요한 역할을 할 것으로 예상되고 있다.Methods of analyzing diseases or abnormalities in the patients' lungs include bronchoalveolar lavage cells and airway mucosal biopsies. Each method has different areas of the airway observed and has different advantages and disadvantages. Bronchoalveolar lavage cells do not directly reflect the changes in airway tissues compared to airway mucosal biopsies.However, in the case of eosinophils and neutrophils, the cells may move blood and airway lumens more frequently than biopsies. More accurate results can be obtained with bronchoalveolar lavage fluid (Beasley, R., Roche, WR, Roberts, JA, Holgate, ST, 1989. Cellular events in the bronchi in mild asthma and after bronchial provocation.Am. Rev. Respir. Dis. 139 pp806-817). However, sampling methods such as bronchoalveolar lavage and airway mucosal biopsy, which are traditionally used for lung disease screening, have placed a heavy burden on patients, which has resulted in limitations and demands simpler sampling methods. Therefore, the present invention invented the equipment in which the waste breathing condensate is recruited to the collecting container by the temperature difference by contacting the waste breathing apparatus with the cooling device into which ice is put. In this way, it is possible to easily check for lung abnormalities by analyzing the collected condensed aerobic fluid. Pulmonary disease testing by component analysis of condensed aerobic condensate in Koreans has not been conducted yet. This method is expected to play an important role in the examination, prediction, diagnosis and treatment of clinical lung abnormalities.
본 고안은 환자에게 부담을 주지 않고 간단하게 폐호기 속의 성분을 수집하는 데 그 목적이 있다. 환자로부터 간단하게 폐 기도안의 성분을 호기를 통해 폐호기 응결액 포집기로 모집한 다음, 여러 가지 생화학적, 산화적 또는 생물학적 지표들의 변화를 측정 및 분석하여 쉽게 폐 질환 및 이상 여부를 알아낼 수 있다. 본 장치는 구조가 간단하여 휴대가 가능하며 저가로 생산이 가능하다.The present invention aims to simply collect the components in the lungs without burdening the patient. From the patient, the components of the lung airway can simply be recruited through the exhalation into the pulmonary aerobic condensate collector, and then measured and analyzed for changes in various biochemical, oxidative or biological indicators to easily determine lung disease and abnormalities. The device is simple in structure, portable, and inexpensive to produce.
본 고안은 환자가 호흡을 위하여 입으로 부는 마우스피스(1), 외부로부터 들이마신 공기가 들어가는 첫 번째 원웨이 밸브(2), 폐호기가 냉각장치 쪽으로 선택적으로 잘 이동하도록 도와주는 두 번째 원웨이 밸브(3), 폐호기와 접촉하여 폐호기를 응결시키는 냉각장치(4), 폐호기 응결액을 모으는 포집통(5) 및 폐호기가 나갈 수 있는 호기 배출관(6)을 포함함을 특징으로 하는 휴대가능한 폐호기 응결액 포집기를 제공한다.The present invention provides a mouthpiece for the patient to breathe (1), the first one-way valve (2) where the air breathed in from the outside, and the second one-way to help the respirator selectively move to the cooling system. A valve (3), a cooling device (4) in contact with the waste exhaler to condense the waste exhalation, a collecting vessel (5) for collecting condensation of the waste exhalation, and an exhalation discharge pipe (6) through which the waste exhalation can exit; It provides a portable waste respirator condensate collector.
실시예Example
환자가 마우스피스(1)에 입을 대고 공기를 들이마시면 첫 번째 원웨이 밸브(2)를 통하여 공기가 들어가고 내쉬는 폐호기는 응결액 포집통(5)에 연결되어 있는 두 번째 원웨이 밸브(3)를 통해 포집통안으로 들어가 냉각장치(4)에 접촉하여 기온차이에 의하여 폐호기의 응결액이 냉각장치의 표면에 물방울처럼 부착하게 되며 그 양이 점차 증가하면서 포집통(5) 아래 부분에 모이게 된다. 냉각장치에는 얼음 등 온도가 차가운 물질을 넣거나 기계장치를 사용한다. 5분 정도 입에다 대고 호흡을 하면 보통 약 1ml 정도의 폐호기 응결액이 포집통에 모이게 된다. 이 응결액의 내용물중에서 여러 생화학적, 산화적 및 생물학적 지표들의 농도 차이를 정량함으로써 폐 속 이상의 여부를 검사할 수 있다.When the patient breathes air into the mouthpiece (1), the air enters and exhales through the first one-way valve (2) and the second exhalation valve (3) connected to the condensate reservoir (5). The condensation liquid of the wastewater aspirator adheres to the surface of the cooling device as water droplets due to the temperature difference and collects in the lower part of the collecting container 5 as the amount gradually increases. . The chiller is equipped with cold material such as ice or mechanical equipment. If you breathe in your mouth for five minutes, approximately 1 ml of condensation fluid will collect in the collection bin. Lung abnormalities can be examined by quantifying the difference in concentrations of various biochemical, oxidative and biological indicators in the contents of the condensate.
본 고안에 따른 폐호기 응결액 포집기는 폐 기도의 이상을 환자에게서 기관지폐포세척세포 또는 기도점막생검 같은 큰 부담을 주지 않고 간단히 측정할수 있게 하고 시간도 대폭 단축시켜주므로 대기오염이 심각해지는 현대에 각종 폐질환 및 이상에 대한 검사, 예측, 진단 및 치료에서 인간에게 매우 유용하게 사용될 것으로 기대된다. 또한 냉각장치에 얼음을 사용하면 소형이고 가벼워 쉽게 휴대 사용이 가능하다.Pulmonary respiratory condensate collector according to the present invention enables simple measurement of lung airway abnormalities without significant burden such as bronchoalveolar lavage cells or airway mucosal biopsy and greatly shortens the time. It is expected to be very useful for humans in the examination, prediction, diagnosis and treatment of lung diseases and abnormalities. In addition, when ice is used in the cooling system, it is compact and light, so it can be easily carried.
도1은 본 발명에 의한 장치의 측면도이다.1 is a side view of the apparatus according to the present invention.
도2는 본 발명에 의한 장치의 평면도이다.2 is a plan view of the apparatus according to the present invention.
도면의 주요 부분에 대한 부호의 설명Explanation of symbols for the main parts of the drawings
1: 마우스피스1: mouthpiece
2: 원웨이 밸브2: one-way valve
3: 원웨이 밸브3: one-way valve
4: 냉각장치4: chiller
5: 응결액 포집통5: condensate collector
6: 호기 배출관6: exhalation discharge pipe
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1020040028018AKR100593871B1 (en) | 2004-04-22 | 2004-04-22 | Wastewater Condensate Collector Using Cooling System |
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1020040028018AKR100593871B1 (en) | 2004-04-22 | 2004-04-22 | Wastewater Condensate Collector Using Cooling System |
| Publication Number | Publication Date |
|---|---|
| KR20050102576Atrue KR20050102576A (en) | 2005-10-26 |
| KR100593871B1 KR100593871B1 (en) | 2006-06-30 |
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020040028018AExpired - LifetimeKR100593871B1 (en) | 2004-04-22 | 2004-04-22 | Wastewater Condensate Collector Using Cooling System |
| Country | Link |
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|---|---|
| KR100593871B1 (en) | 2006-06-30 |
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