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JPS646267A - 2-benzopyran derivative - Google Patents

2-benzopyran derivative

Info

Publication number
JPS646267A
JPS646267AJP62326227AJP32622787AJPS646267AJP S646267 AJPS646267 AJP S646267AJP 62326227 AJP62326227 AJP 62326227AJP 32622787 AJP32622787 AJP 32622787AJP S646267 AJPS646267 AJP S646267A
Authority
JP
Japan
Prior art keywords
formula
compound
alkyl
diphenylalkyl
aralkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP62326227A
Other languages
Japanese (ja)
Inventor
Tatsutsugu Nozawa
Soji Kanao
Ko Suzuki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Daiichi Pharmaceutical Co Ltd
Original Assignee
Daiichi Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daiichi Pharmaceutical Co LtdfiledCriticalDaiichi Pharmaceutical Co Ltd
Priority to JP62326227ApriorityCriticalpatent/JPS646267A/en
Publication of JPS646267ApublicationCriticalpatent/JPS646267A/en
Pendinglegal-statusCriticalCurrent

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Abstract

NEW MATERIAL:A compound of formula I [R1, R2 are H, halogen, alkyl, alkoxy, trihalomethyl, hydroxyl, amino, alkylamino, or incorporate to form alkylenedioxy; n is 1-5; R<3> is H, alkyl, aralkyl; R4 is formula IV (m is 1-5; lis 1, 2; R5 is H, alkyl, aralkyl, diphenylalkyl), diphenylalkyl] and its salt. EXAMPLE:3,4-Dihydro-N-(3,3-diphenylpropyl)-1H-2-benzopyran-1-methylamine monomaleate. USE:It has action to inhibit the formation of activated oxygen and is used as a prophylactic or remedy for radiation injury. PREPARATION:For example, a compound of formula II is allowed to react with a compound of the formula: XCO-R6 (X is halogen, R6 is formula V) or the formula: O(COR6)2 to form a compound of formula III, which is reduced to give the compound of formula I.
JP62326227A1987-02-041987-12-232-benzopyran derivativePendingJPS646267A (en)

Priority Applications (1)

Application NumberPriority DateFiling DateTitle
JP62326227AJPS646267A (en)1987-02-041987-12-232-benzopyran derivative

Applications Claiming Priority (2)

Application NumberPriority DateFiling DateTitle
JP24042871987-02-04
JP62326227AJPS646267A (en)1987-02-041987-12-232-benzopyran derivative

Publications (1)

Publication NumberPublication Date
JPS646267Atrue JPS646267A (en)1989-01-10

Family

ID=26361520

Family Applications (1)

Application NumberTitlePriority DateFiling Date
JP62326227APendingJPS646267A (en)1987-02-041987-12-232-benzopyran derivative

Country Status (1)

CountryLink
JP (1)JPS646267A (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication numberPriority datePublication dateAssigneeTitle
US10196403B2 (en)*2016-07-292019-02-05Sunovion Pharmaceuticals Inc.Compounds and compositions and uses thereof
US10780074B2 (en)2017-08-022020-09-22Sunovion Pharmaceuticals Inc.Compounds and uses thereof
US11077090B2 (en)2016-07-292021-08-03Sunovion Pharmaceuticals Inc.Compounds and compositions and uses thereof
US11136304B2 (en)2019-03-142021-10-05Sunovion Pharmaceuticals Inc.Salts of a heterocyclic compound and crystalline forms, processes for preparing, therapeutic uses, and pharmaceutical compositions thereof

Cited By (9)

* Cited by examiner, † Cited by third party
Publication numberPriority datePublication dateAssigneeTitle
US10196403B2 (en)*2016-07-292019-02-05Sunovion Pharmaceuticals Inc.Compounds and compositions and uses thereof
CN110088107A (en)*2016-07-292019-08-02赛诺维信制药公司Compounds, compositions and uses thereof
JP2019525939A (en)*2016-07-292019-09-12サノビオン ファーマシューティカルズ インクＳｕｎｏｖｉｏｎ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｉｎｃ． Compounds and compositions and their use
US10927124B2 (en)2016-07-292021-02-23Sunovion Pharmaceuticals Inc.Compounds and compositions and uses thereof
US11077090B2 (en)2016-07-292021-08-03Sunovion Pharmaceuticals Inc.Compounds and compositions and uses thereof
US11958862B2 (en)2016-07-292024-04-16Sumitomo Pharma America, Inc.Compounds and compositions and uses thereof
US10780074B2 (en)2017-08-022020-09-22Sunovion Pharmaceuticals Inc.Compounds and uses thereof
US11491133B2 (en)2017-08-022022-11-08Sunovion Pharmaceuticals Inc.Heteroaryl-isochroman compounds and uses thereof
US11136304B2 (en)2019-03-142021-10-05Sunovion Pharmaceuticals Inc.Salts of a heterocyclic compound and crystalline forms, processes for preparing, therapeutic uses, and pharmaceutical compositions thereof

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