JPS5830666A - Buffer stabilizer - Google Patents

Abstract

PURPOSE:To raise safety by installing a device that detects the flow of a buffer solution and cutting off the power source to temperature regulating device and so on or sounding an alarm buzzer or other safety means. CONSTITUTION:A buffer solution 16 in a vessel 15 for the buffer solution is supplied by means of a circulation pump 25 through a pipe 17 to a pipe 27 that is wound round a heating drum 26. The buffer solution whose temperature has reached a constant temperature through the heating drum 26 is returned again to the buffer solution vessel 15 by traversing the wall. Here the oxygen dissolved in the buffer solution is balanced by the multiple effect of the negative effect to the buffer solution and pulsating flow effect by the circulation pump 25 and the heating effect by the heating drum 26. While the buffer solution is circulating, the light flux from the light source 19 gets into a light receiving element 21 to turn on a switching circuit and supplies electric power of the power source 24. If the buffer solution is exhausted, total reflection develops by the difference of the reflective indices by passing from a glass tube 20' to the air and incident light to the light receiving element 21 to turn off the switching circuit and overheat is avoided.

Description

Translated fromJapanese

【発明の詳細な説明】本発明は、生体検査鳳１置−等一番ご用いられる緩衝液
を複数回加熱することにより緩衝液の温度の安定化と溶
存酸素の平衡化をはかる装置に関する。DETAILED DESCRIPTION OF THE INVENTION The present invention relates to a device that stabilizes the temperature of a buffer solution and equilibrates dissolved oxygen by heating the buffer solution, which is most commonly used in biological examinations, multiple times.

例えば、緩衝液の温度及び溶存酸素の安定化をはかる装
置としては第１図に示す装置が提案査れていた。ここで
、緩衝液７は緩衝液用容器／３にはいっている。緩衝液
７を一定温度に保つために緩衝液７内に投込み用加熱ヒ
ータＳと温度検出器ｌがある。これらと電源／に接続す
る制御装置２によって緩衝液の温度が一定温度に保つよ
う温度調節される。又、モータ３により先端がプロペラ
状の攪拌軸乙を回転させることによって緩衝液７のなか
を攪拌しなからバブリングを行って、緩衝液７の温度を
一定に保つとともに溶存酸素の平衡化をはかつていた。For example, a device shown in FIG. 1 has been proposed as a device for stabilizing the temperature and dissolved oxygen of a buffer solution. Here, the buffer solution 7 is contained in the buffer solution container/3. In order to maintain the buffer solution 7 at a constant temperature, there is an immersion heater S and a temperature detector l inside the buffer solution 7. A control device 2 connected to these and a power supply adjusts the temperature of the buffer solution to maintain it at a constant temperature. In addition, by rotating a stirring shaft B with a propeller-shaped tip using the motor 3, the buffer solution 7 is not stirred but bubbled to keep the temperature of the buffer solution 7 constant and to equilibrate the dissolved oxygen. I used to be.

又、一定湿度に保たれた緩衝液７を管ｔを通してシリン
ダ９により吸入し、吸入された緩衝液は所定の装置、た
とえば測定セルフ／１ノスル／２．又はその他に必要な
装置／ｌに送られるために切換バルブＩＯを通してシリ
ンダー９より排出することにより所定の装置に送られる
。Further, a buffer solution 7 kept at a constant humidity is sucked into the cylinder 9 through a tube t, and the sucked buffer solution is stored in a predetermined device, such as a measuring cell/1 nostle/2. Alternatively, it is sent to a predetermined device by discharging from the cylinder 9 through the switching valve IO in order to be sent to other necessary devices/l.

このような従来の装置ではバブリングを用いても、緩衝
液の液深が深くないと、充分溶存酸素の平衡化ができな
いし、バブリング用の酸素ガスに不純物が入っていると
、緩衝液内に前記不純物が溶けこんでしまうし・、水分
が蒸発し易すかった。In such conventional devices, even if bubbling is used, dissolved oxygen cannot be sufficiently equilibrated unless the buffer solution depth is deep, and if the oxygen gas used for bubbling contains impurities, the buffer solution may The impurities were dissolved and the water evaporated easily.

又緩衝液が発泡性だとバブリングできない欠点があった
。又、緩衝液用容器１３内に温度検出器ｌや投込みヒー
タ！や攪拌軸６等がはいっているため緩衝液用容器／３
内の緩衝液７を新らしい緩衝液と交換する時、これら温
度検出器ｌや投込みヒータＳや攪拌軸≦等を取り除いて
行なわなければならないので手間がかかり非常に面倒で
あった。Moreover, if the buffer solution is foamable, there is a drawback that bubbling cannot be performed. Also, there is a temperature detector l and an immersion heater inside the buffer solution container 13! Buffer solution container/3 because it contains a stirring shaft 6, etc.
When replacing the buffer solution 7 in the buffer with a new buffer solution, the temperature detector L, the immersion heater S, the stirring shaft, etc. must be removed, which is very time-consuming and troublesome.

又、緩衝液用容器／３内の緩衝液７を所定の装置に送る
時に、緩衝液７から管が所定の装置に至る迄、長い時に
は管か緩衝液の温度を奪ってしまい、従って所定の装置
に達つした緩衝液の温度゛が緩衝液゛７の温度よりさが
ってしまう欠点があった。Also, when sending the buffer solution 7 in the buffer container/3 to a predetermined device, if it takes a long time for the tube to reach the predetermined device from the buffer solution 7, the temperature of the tube or the buffer solution is taken away, and therefore the predetermined temperature is lost. There was a drawback that the temperature of the buffer solution that reached the apparatus was lower than the temperature of the buffer solution "7".

更に、第１図の構成のような装置では、緩衝液用容器／
３内の緩衝液７がなくなったときでも容器１３がほぼ密
閉されているので緩衝液７の蒸気が充満しても温度検出
器ｔ１投込みヒータ５１制御装置コは作動し続けて加熱
状態で空だきとなり非常に危険である。Furthermore, in an apparatus having the configuration shown in FIG.
Even when the buffer solution 7 in the buffer solution 7 is used up, the container 13 is almost sealed, so even if the buffer solution 7 is filled with vapor, the temperature sensor t1, the input heater 51, and the control device continue to operate and remain heated. It is extremely dangerous.

本発明の目的は、上述のような欠点を改良するもので緩
衝液用容器内の緩衝液を循環ポンプで緩衝液容器の外側
へ取り出して温度１ｓ節装置にて緩衝液を一定温度にし
て後、再び緩衝液用容器内に緩衝液を戻すことにより緩
衝液の交換を容易ならしめ１又、所定の装置へ緩衝液を
送る場合、緩衝液容器内の緩衝液を送水手段で取り出し
て所定の装置に達する前に再び温度調節装置にて緩衝液
が一定温度になるよう加熱することにより一定温度の緩
衝液を所定の装置に送ることを可能ならしめ、又、緩衝
液用容器内から循環ポンプで取り出した緩衝液を管の中
に流し、その流れを検知する装置をとりつけることによ
り緩衝液がほとんどなくなった場合でも、検知装置によ
り温度調節装置等の電源を切るか、警告ブザー等を鳴ら
すことにより安全性の向上をはかり、更には循環ポンプ
の緩衝液への除圧作用と温度調節装置による加熱により
、緩衝液の溶存酸素が平衡化することができる緩衝液の
安定化装置を提供することにある。The purpose of the present invention is to improve the above-mentioned drawbacks, and the purpose of the present invention is to take out the buffer solution in the buffer solution container to the outside of the buffer solution container using a circulation pump, bring the buffer solution to a constant temperature using a temperature control device for 1 second, and then By returning the buffer solution to the buffer solution container again, the buffer solution can be easily exchanged. 1.Also, when sending the buffer solution to a predetermined device, the buffer solution in the buffer solution container is taken out by a water supply means and transferred to the predetermined amount. By heating the buffer solution to a constant temperature using a temperature control device before reaching the device, it is possible to send the buffer solution at a constant temperature to the specified device. By flowing the buffer solution taken out into the pipe and installing a device to detect the flow, even if the buffer solution is almost gone, the detection device can turn off the power to the temperature control device, etc., or sound a warning buzzer, etc. To provide a buffer solution stabilizing device which improves safety and further enables dissolved oxygen in the buffer solution to be equilibrated by a pressure-reducing action on the buffer solution by a circulation pump and heating by a temperature control device. It is in.

以下、本発明の構成を実施例に従って説明する。Hereinafter, the configuration of the present invention will be explained according to examples.

第、２図は、本発明の一実施例を示す構成図で、第３図
は他の一実施例を示す構成図である。第２図（ａ）にお
いて、緩衝液用言Ｈ／！内に一定温度（たとえば生体の
測定温度にあわせると３７℃）の緩衝液１６が入ってい
る。管１７は循環ポンプ２５の流入口に接続され、循環
ポンプの流出口から出た緩衝液は加熱ドラム２乙にらせ
ん状に巻かれている管コアを通る。2 are block diagrams showing one embodiment of the present invention, and FIG. 3 is a block diagram showing another embodiment. In FIG. 2(a), the buffer term H/! A buffer solution 16 at a constant temperature (for example, 37° C. in accordance with the measured temperature of a living body) is contained inside. The tube 17 is connected to the inlet of a circulation pump 25, and the buffer solution leaving the outlet of the circulation pump passes through a tube core wound helically around the heating drum 2B.

らせん状に巻いた管２７の始点がａで終点がａ′となっ
ている。加熱ドラム２ｇには、ヒーターＩ！：温度検出
器を内蔵しており温度制御器２ｒに接続されている。こ
れら、らせん状に巻かれている管２７と、温度検出器と
ヒータを内蔵せる加熱ドラム、２４と、温度制御器２ｔ
とおあわせで第７の温度調節装置１０／と呼ぶ。らせん
状に巻かれている管２７の終点ａ′は循環ポンプ、２５
を経由して、再び緩衝液用容器／ｊの壁に沿った形で／
ｒのようガラス管２０’を通り受光素子２１に入る。受
光素子には増幅器２２が接続されてスイッチング回路２
３をスイッチングする。これにより電源２ｑは循環ポン
プ２ｊ等の動力源となっている（循環ポンプ２夕に接続
した以外は、図示せず）動力源のスイッチングをする。The starting point of the spirally wound tube 27 is a and the ending point is a'. Heater I is attached to the heating drum 2g! : It has a built-in temperature detector and is connected to the temperature controller 2r. These include a spirally wound tube 27, a heating drum 24 containing a temperature detector and a heater, and a temperature controller 2t.
Together, they are referred to as a seventh temperature control device 10/. The end point a' of the spirally wound pipe 27 is a circulation pump, 25
via and again along the wall of the buffer container/j/
The light passes through the glass tube 20' and enters the light receiving element 21 as shown in r. An amplifier 22 is connected to the light receiving element, and a switching circuit 2
Switch 3. As a result, the power source 2q switches the power source for the circulation pump 2j and the like (not shown except that it is connected to the circulation pump 2j).

一方緩衝液／６に菅３乙が入っており、管３乙は切換バ
ルブ３０に接続され、切換バルブは送水手段として用い
るシリンダ２９と、加熱ドラム３．２に巻かれている管
３３の始点すに接続されている。加熱ドラム３コには管
３３が巻かれており、その始点はｂで、終点はｂ′であ
る。加熱ドラム３．２はヒータと温度検出器を内蔵して
おり、ヒータと温度検出器は温度制御器３１に接続され
ている。ヒータと温度検出器を内蔵せる加熱ドラム３２
と加゛熱ドラム３２に巻かれている管３３と温度制御器
３１をあわせて第２の温度調節装置と呼ぶ。加熱ドラム
３２に巻かれている管３３の終点ｂ′は切換えパルプ３
１Ｉに接続され、切換パルプ３ｔは所定の装置（測定セ
ル３Ｓ、ノズル３≦、その他必要な装置３７）に接続さ
れている。第２図の）は加熱ドラム２乙や３２及び温度
制御器２ｇや３／の拡大図で加熱ドラムＩＩ／は、熱伝
達材３７が入っており、その外側を管＋、２が巻かれて
いる。熱伝達材３７の中にはヒータ３１と温度検出器３
９が入つ、ており、それぞれ温度制御器ψＯに接続され
ている。第３図は、第１の温度調節装置１０／と第２の
温度調節装置１０２を共通の温度調節装置１０３にした
一実施例の断面図で、熱伝熱体ＵＩＩは熱伝導率の良い
材料（金属等）でできており円筒形である。円筒形の端
面は紙面に垂直な面で、その−面からヒータ１ｔ−ｓと
温度検出器ｌＩｔが熱伝達体１ＩＩＩに入っている。こ
の熱伝熱体１ｌｌＩのまわりに第一図（ａ）で示す循環
ポンプ−５からの管が始点ａとし終点ａ′として内側に
巻かれている。その外側には、更に第１図（ａ）で示す
切換パルプ３０からの管が始点すとし終点ｂ′として外
側に第２図に示す如くらせん状に巻かれている。管の外
側には必要に応じて断熱材ｌＩ３が覆っている。ヒータ
ｔＳと温度検出器ＩＩ乙は温度調節器ｌ１７に接続され
ている。即ち、番２図に示しである点線内の部分（第１
の温度調節装置１０／と第２の温度調節装置１０２）が
第３図に示される共通の温度調節装置１０３にとってか
えられる。On the other hand, the buffer solution /6 contains a tube 3, and the tube 3 is connected to a switching valve 30, which is the starting point of the cylinder 29 used as a water supply means and the tube 33 wound around the heating drum 3.2. connected to. A tube 33 is wound around the three heating drums, and its starting point is b and its ending point is b'. The heating drum 3.2 contains a heater and a temperature detector, and the heater and temperature detector are connected to the temperature controller 31. Heating drum 32 with a built-in heater and temperature detector
The tube 33 wound around the heating drum 32 and the temperature controller 31 are collectively referred to as a second temperature controller. The end point b' of the tube 33 wound around the heating drum 32 is the switching pulp 3
1I, and the switching pulp 3t is connected to predetermined devices (measuring cell 3S, nozzle 3≦, and other necessary devices 37). ) in Fig. 2 is an enlarged view of the heating drums 2 O and 32 and the temperature controllers 2 g and 3. The heating drum II contains a heat transfer material 37, and the tubes + and 2 are wound around the outside of it. There is. Inside the heat transfer material 37 are a heater 31 and a temperature detector 3.
9 are inserted, and each is connected to a temperature controller ψO. FIG. 3 is a sectional view of an embodiment in which the first temperature control device 10/ and the second temperature control device 102 are used as a common temperature control device 103, and the heat transfer body UII is made of a material with good thermal conductivity. It is made of (metal, etc.) and has a cylindrical shape. The cylindrical end face is a face perpendicular to the plane of the paper, and the heater 1t-s and the temperature detector lIt enter the heat transfer body 1III from the - face. A tube from the circulation pump 5 shown in FIG. 1(a) is wound inward around this heat transfer body 1llI with a starting point a and an ending point a'. On the outside thereof, a tube from the switching pulp 30 shown in FIG. 1(a) is wound spirally outward as shown in FIG. 2 with a starting point and an ending point b'. The outside of the tube is covered with a heat insulating material II3 as required. The heater tS and the temperature detector IIB are connected to the temperature regulator l17. That is, the part within the dotted line shown in Figure 2 (the first
temperature regulating device 10/and second temperature regulating device 102) are replaced by a common temperature regulating device 103 shown in FIG.

次に、動作の説明をすると、第２図（ａ）において緩衝
液用容器ｌｊ内の緩衝液１６は循環ポンプ２Ｓにより管
１７を通して吸い上げられて、加熱ドラム２乙に巻かれ
ている管−７に供給される。Next, to explain the operation, in FIG. 2(a), the buffer solution 16 in the buffer solution container lj is sucked up through the pipe 17 by the circulation pump 2S, and the buffer solution 16 is sucked up through the pipe 17 wound around the heating drum 2B. supplied to

加熱ドラム２乙は温度制御器−ｌにより一定温度にされ
ているので、その熱が加熱ドラムＪ４に巻かれている管
２７に供給され、従ってその中を流れている緩衝液の温
度が一定になる。以上のように第１Ｊ）温度調節装置１
０／により緩衝液は一定温度となる。加熱ドラム２６番
つうじ一定温度にな９た緩衝液は、再び緩衝液用容器ｌ
Ｓの壁を仮作用との相乗効果により緩衝液の溶存酸素の
平衡化が行なわれる。再び戻った緩衝液を緩衝液用容器
／Ｓの壁を伝わわせるのは、この溶存酸素を排出するた
めである。これによって一定の溶存酸素を含んだ一定温
度の緩衝液／乙が緩衝液用容器／ｊに存在することにな
る。Since the heating drum 2B is kept at a constant temperature by the temperature controller-l, the heat is supplied to the tube 27 wound around the heating drum J4, so that the temperature of the buffer solution flowing inside it is kept constant. Become. As described above, 1st J) Temperature control device 1
0/ causes the buffer solution to have a constant temperature. The buffer solution that has reached a constant temperature through heating drum No. 26 is returned to the buffer solution container l.
Equilibration of dissolved oxygen in the buffer takes place due to the synergistic effect of S on the wall and the pseudo-action. The reason why the returned buffer solution is passed through the wall of the buffer solution container/S is to discharge this dissolved oxygen. As a result, a buffer solution /B containing a certain amount of dissolved oxygen and a constant temperature is present in the buffer solution container /j.

前述せるように緩衝液が循環している間は、光源／９か
ら出た光束は、受光素子、２／に正しく光束が入り、受
光素子２１の入力信号は増幅器２２により増幅されてス
イッチング回路をオン状態にして電源２１の電力を供給
するが、もし緩衝液がなくなった場合にはガラス管２ｏ
１には緩衝液が入っておらずガラス管２０’から空気層
への屈折率の大きな差により全反射がおきて、受光素子
２　、／には、わずかな光しか入射しなくなるのでスイ
ッチング回路はオフ状態となり、すべての動作を停止す
ることにより過熱防止等の役割りを果す。緩衝液用容器
ｌｊ内の緩衝液ｌ≦は必要に応じて送水手段として用い
るシリンダー／乙により切換えパルプ３０を通して吸引
される。次に、切換パルプ３０を緩衝液側から加熱ドラ
ム３２側に切り換えてシリンダー２９内の緩衝液を排出
する。排出された緩衝液は加熱ドラム３２に巻かれてい
る管３３に供給される。加熱ドラム３２は温度制御器３
／により一定温度にされているので、その熱が加熱ドラ
ム３２に巻かれている管３８に供給され、従ってその中
を流れている緩衝液の温調が一定になる、以上のように
第２の温度調節装置１０２により緩衝液は一定温度とな
る。切換えパルプ３１は予め所定の装置、たとえば測定
セル３ｊに切り換えられているので、一定温度となった
緩衝液は測定セル３Ｓに供給せられるわけである。第２
図り）の動作説明は簡単のため省略する。As mentioned above, while the buffer solution is circulating, the light beam emitted from the light source /9 correctly enters the light receiving element 2/, and the input signal of the light receiving element 21 is amplified by the amplifier 22 and sent to the switching circuit. Turn it on and supply power to the power supply 21, but if the buffer runs out, the glass tube 2o
1 does not contain a buffer solution, and total reflection occurs due to the large difference in refractive index from the glass tube 20' to the air layer, and only a small amount of light enters the light receiving element 2, /, so the switching circuit is It goes into the off state and stops all operations, which serves to prevent overheating. The buffer solution l≦ in the buffer solution container lj is sucked through the switching pulp 30 by a cylinder/O used as a water supply means as necessary. Next, the switching pulp 30 is switched from the buffer solution side to the heating drum 32 side to discharge the buffer solution in the cylinder 29. The discharged buffer solution is supplied to a tube 33 wrapped around a heating drum 32. The heating drum 32 is the temperature controller 3
Since the temperature is maintained at a constant temperature by The temperature control device 102 keeps the buffer solution at a constant temperature. Since the switching pulp 31 has been switched in advance to a predetermined device, for example, the measurement cell 3j, the buffer solution at a constant temperature is supplied to the measurement cell 3S. Second
The explanation of the operation of (Figure) will be omitted for simplicity.

第３図においては、循環ポンプ２ｊ（第２図）よって流
れてきた緩衝液は、管の始点ａに入り、予めヒータグ５
と温度制御器ＩＩ７と温度検出器ＩＩ乙に゛より一定温
度に温められている熱伝達体ｌＩりの熱をうけて一定温
度に温められて管の終点ａ′に達して、緩衝液用容器／
左（第２図）に戻される。一方、送水手段であるシリン
ダー／乙（第２図）から排出された緩衝液は菅の始点す
に入り、予めヒータｌよと温度制御器ｌＩ７と温度検出
器ｔｌ乙により一定温度に温められている熱伝達体１Ｉ
ｌｌの熱をうけて一定温度に温められて管の終点ｂ′に
達して切換えバルブ３ＩＩを通して所定の装置に送られ
る。このようにすると第２図に示されているように第１
の温度調節装置１０／と第２の湿度調節装置１０２を共
通の温度調節装置１０３におきかえられて装置の小型化
、安価′さに役立つ。In FIG. 3, the buffer solution flowing by the circulation pump 2j (FIG. 2) enters the starting point a of the pipe and is preliminarily connected to the heater tag 5.
The temperature controller II7 and the temperature detector IIB receive heat from the heat transfer body II, which is heated to a constant temperature by the temperature controller II7 and the temperature detector IIB, and the buffer solution container is heated to a constant temperature and reaches the end point a' of the tube. /
It is returned to the left (Figure 2). On the other hand, the buffer solution discharged from the cylinder/B (Fig. 2), which is the water supply means, enters the starting point of the tube and is preheated to a constant temperature by the heater L, temperature controller I7, and temperature detector Tl. Heat transfer body 1I
It is heated to a constant temperature by receiving heat of 1 1, reaches the end point b' of the pipe, and is sent to a predetermined device through a switching valve 3II. In this way, the first
The temperature control device 10/ and the second humidity control device 102 can be replaced with a common temperature control device 103, which contributes to miniaturization and low cost of the device.

本発明は上述のように構成および動作することによって
、緩衝液用容器内の緩衝液をつねに一定り緩衝液内の溶
存酸素の平衡化をはかり、又、緩衝液用容器内の緩衝液
がなくなっても過熱防止し、更には所定の装置に緩衝液
を送る場合、途中で加熱することにより、一定温度の緩
衝液を送ることができる。更に、緩衝液用容器外に温度
調節装置を設けたことにより、緩衝液用容器内の緩衝液
を簡単に取り換えることのできる効果を有する。By having the structure and operation as described above, the present invention keeps the buffer in the buffer container constant, balances the dissolved oxygen in the buffer, and prevents the buffer in the buffer container from running out. Furthermore, when sending a buffer solution to a predetermined device, by heating the buffer solution midway through, it is possible to send the buffer solution at a constant temperature. Furthermore, by providing a temperature control device outside the buffer solution container, there is an effect that the buffer solution in the buffer solution container can be easily replaced.

本発明はこれのみに限定されることなく、第１図の所定
の装置で、その他必要な装置と測定セルは別個に独自の
加熱装置で緩衝液を一定温度とする時には、第２の温度
調節装置をノズルの近く、即ちノズル３乙と切換バルブ
３グの間に配置することができる。The present invention is not limited to this, but when the predetermined apparatus shown in FIG. The device can be placed close to the nozzle, ie between the nozzle 3B and the switching valve 3G.

【図面の簡単な説明】[Brief explanation of drawings]

第１図は、従来の緩衝液安定化装置の構成図、第２図（
ａ）は本発明の緩衝液安定化装置の一実施例を示す構成
図、第２図（ｂ）は第１及び第２の温度調節装置を示す
図、第３図は共通の温度調節装置を示す一実施例の断面
図である。／Ｓ・・・緩衝液用容器１６・・・緩衝液２Ｓ・・・循環ポンプ２乙、３２・・・加熱ドラム２７．３３・・・加熱ドラムに巻かれた管２１．３／・
・・湿度制御器２ｑ・・・送水手段として用いるシリンダーＩＩ＋・・
・熱伝達体ＩＩＳ・・・ヒータｌ乙・・・濡度検ＩＯＢ器ＩＩ７・・・温度制御器１０／・・・第１の温度調節装置１０２・・・第２の温度調節装置１０２・・・共通の温度調節装置Figure 1 is a block diagram of a conventional buffer stabilization device, and Figure 2 (
a) is a block diagram showing one embodiment of the buffer stabilizing device of the present invention, FIG. 2(b) is a diagram showing the first and second temperature control devices, and FIG. 3 is a diagram showing the common temperature control device. FIG. /S...Buffer solution container 16...Buffer solution 2S...Circulation pump 2, 32...Heating drum 27.33...Pipe wound around the heating drum 21.3/...
...Humidity controller 2q...Cylinder II+ used as water supply means...
・Heat transfer body IIS...Heater lB...Wetness detector IOB II7...Temperature controller 10/...First temperature adjustment device 102...Second temperature adjustment device 102...・Common temperature control device

Claims (1)

Translated fromJapanese

【特許請求の範囲】／、　一定温度の緩衝液を入れて置くための緩衝液用容
器と、該緩衝液用容器内の緩衝液を取り出して加熱し、
再び前記緩衝液用容器内に戻すための循環ポンプ並びに
第７の温度調節装置と、前記緩衝液用容器内の緩衝液を
所定の装置に送るための送水手段と、前記送水手段によ
り送水される前記緩衝液を、再び一定の温度になるよう
加熱するための第２の温度調節装置とを備えたことを特
徴とする緩衝液の安定化装置。２、　前記第１の温度調節装置と前記第２の温度調節装
置を共通の温度調節装置にしたことを特徴とする特許請
求の範囲第１項記載の緩衝液の安定化装置。３一定温度の緩衝液を入れて置くための緩衝液用容器と
、該緩衝液用容器内の緩衝液を取り出して加熱する第１
の温度調節装置と、緩衝液を再び緩衝液用容器に戻すた
めの循環ポンプとを管で接続し、流れの方向に対し第１
の温度調節装置に対し循環ポンプを後方に配置すること
により、第１の温度調節装置に用いている管の中の緩衝
液に除圧作用を生ぜしめたことを特徴とする緩衝液の安
定化装置。[Scope of Claims] / A buffer solution container for holding a buffer solution at a constant temperature; a buffer solution in the buffer solution container is taken out and heated;
A circulation pump and a seventh temperature control device for returning the buffer solution to the buffer solution container, a water supply means for sending the buffer solution in the buffer solution container to a predetermined device, and water supplied by the water supply means. A buffer solution stabilizing device comprising: a second temperature control device for heating the buffer solution to a constant temperature again. 2. The buffer solution stabilization device according to claim 1, wherein the first temperature control device and the second temperature control device are a common temperature control device. 3. A buffer solution container for holding a buffer solution at a constant temperature, and a first container for taking out and heating the buffer solution in the buffer solution container.
The temperature control device and the circulation pump for returning the buffer solution to the buffer container are connected by a pipe, and
Stabilization of a buffer solution characterized in that a circulation pump is placed rearward to the first temperature control device to create a depressurizing effect on the buffer solution in the tube used in the first temperature control device. Device.