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JPS567716A - Preventive and remedy for cerebral angiospasm - Google Patents

Preventive and remedy for cerebral angiospasm

Info

Publication number
JPS567716A
JPS567716AJP8343179AJP8343179AJPS567716AJP S567716 AJPS567716 AJP S567716AJP 8343179 AJP8343179 AJP 8343179AJP 8343179 AJP8343179 AJP 8343179AJP S567716 AJPS567716 AJP S567716A
Authority
JP
Japan
Prior art keywords
angiospasm
compound
cerebral
remedy
preventive
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP8343179A
Other languages
Japanese (ja)
Inventor
Mutsuji Mori
Sakae Takaku
Yasushi Murakami
Yukifumi Noda
Noboru Takano
Tamotsu Yamazaki
Shunichi Hata
Shigeru Takanashi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chugai Pharmaceutical Co Ltd
Original Assignee
Chugai Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chugai Pharmaceutical Co LtdfiledCriticalChugai Pharmaceutical Co Ltd
Priority to JP8343179ApriorityCriticalpatent/JPS567716A/en
Publication of JPS567716ApublicationCriticalpatent/JPS567716A/en
Pendinglegal-statusCriticalCurrent

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Abstract

PURPOSE: A preventive and remedy for angiospasm comprising an anthranilic acid derivative or its salt as an active constituent.
CONSTITUTION: A preventive and remedy for cerebral angiospasm comprising a compound of formula I (X is 1W10C alkylene group) or its salt as an active constituent.The compound with low toxicity has no vasodilator action but thoroughly remits the cerebral angiospasm affecting the prognosis of the cerebral hemorrhage. The cerebral blood vesseil in contact with the compund will not be easily contracted in contact with the arterial blood. The administration may be carried out by dusting 10W1,000mg, preferably 50W100mg, of the disodium salt of the compund on the affected part, or by introducing 1W1,000mg, preferably 10W100mg, of an aqueous solution through a cannula into the affected area of possible angiospasm. The compound of formula I can be obtained by reacting anthranilic acid with a compound of formula II.
COPYRIGHT: (C)1981,JPO&Japio
JP8343179A1979-07-031979-07-03Preventive and remedy for cerebral angiospasmPendingJPS567716A (en)

Priority Applications (1)

Application NumberPriority DateFiling DateTitle
JP8343179AJPS567716A (en)1979-07-031979-07-03Preventive and remedy for cerebral angiospasm

Applications Claiming Priority (1)

Application NumberPriority DateFiling DateTitle
JP8343179AJPS567716A (en)1979-07-031979-07-03Preventive and remedy for cerebral angiospasm

Publications (1)

Publication NumberPublication Date
JPS567716Atrue JPS567716A (en)1981-01-27

Family

ID=13802244

Family Applications (1)

Application NumberTitlePriority DateFiling Date
JP8343179APendingJPS567716A (en)1979-07-031979-07-03Preventive and remedy for cerebral angiospasm

Country Status (1)

CountryLink
JP (1)JPS567716A (en)

Cited By (14)

* Cited by examiner, † Cited by third party
Publication numberPriority datePublication dateAssigneeTitle
EP0156456A1 (en)1984-02-081985-10-02Sawai Pharmaceutical Co., Ltd.[(1,3,-dioxo-1,3-propanediyl)diimino] bisbenzoic acid derivatives and their use
JP2008081895A (en)*2006-09-282008-04-10Daio Paper CorpDisposable glove
JP2008150367A (en)*1997-09-102008-07-03Rutgers The State Univ Of New Jersey Polyanhydrides with therapeutically useful degradation products
WO2009013915A1 (en)*2007-07-252009-01-29Renascience Co., Ltd.Inhibitor of plasminogen activator inhibitor-1
WO2009123241A1 (en)*2008-03-312009-10-08株式会社レナサイエンスInhibitor of plasminogen activator inhibitor-1
US8017714B2 (en)1997-09-102011-09-13Rutgers, The State University Of New JerseyPolyanhydrides with therapeutically useful degradation products
US8741317B2 (en)2010-08-192014-06-03Rutgers, The State University Of New JerseySlow-degrading polymers comprising salicylic acid for undelayed and sustained drug delivery
US8785473B2 (en)2009-03-312014-07-22Renascience Co., Ltd.Plasminogen activator inhibitor-1 inhibitor
US9782432B2 (en)2012-10-252017-10-10Rutgers, The State University Of New JerseyPolymers and methods thereof for wound healing
US9862672B2 (en)2013-05-292018-01-09Rutgers, The State University Of New JerseyAntioxidant-based poly(anhydride-esters)
US10023521B2 (en)2014-06-132018-07-17Rutgers, The State University Of New JerseyProcess and intermediates for preparing poly(anhydride-esters)
US10092578B2 (en)2006-09-132018-10-09Polymerix CorporationActive agents and their oligomers and polymers
US10092537B2 (en)2013-04-152018-10-09Renascience Co., Ltd.Use for PAI-1 inhibitor
US10543162B2 (en)2015-04-102020-01-28Rutgers, The State University Of New JerseyKojic acid polymers

Cited By (17)

* Cited by examiner, † Cited by third party
Publication numberPriority datePublication dateAssigneeTitle
EP0156456A1 (en)1984-02-081985-10-02Sawai Pharmaceutical Co., Ltd.[(1,3,-dioxo-1,3-propanediyl)diimino] bisbenzoic acid derivatives and their use
JP2008150367A (en)*1997-09-102008-07-03Rutgers The State Univ Of New Jersey Polyanhydrides with therapeutically useful degradation products
US8017714B2 (en)1997-09-102011-09-13Rutgers, The State University Of New JerseyPolyanhydrides with therapeutically useful degradation products
US10092578B2 (en)2006-09-132018-10-09Polymerix CorporationActive agents and their oligomers and polymers
JP2008081895A (en)*2006-09-282008-04-10Daio Paper CorpDisposable glove
WO2009013915A1 (en)*2007-07-252009-01-29Renascience Co., Ltd.Inhibitor of plasminogen activator inhibitor-1
JP2009040777A (en)*2007-07-252009-02-26Rena Science:KkPlasminogen activator inhibitor-1 inhibiting agent
US7951806B2 (en)2007-07-252011-05-31Renascience Co., Ltd.Plasminogen activator inhibitor-1 inhibitor
US8415479B2 (en)2008-03-312013-04-09Renascience Co., Ltd.Inhibitor of plasminogen activator inhibitor-1
WO2009123241A1 (en)*2008-03-312009-10-08株式会社レナサイエンスInhibitor of plasminogen activator inhibitor-1
US8785473B2 (en)2009-03-312014-07-22Renascience Co., Ltd.Plasminogen activator inhibitor-1 inhibitor
US8741317B2 (en)2010-08-192014-06-03Rutgers, The State University Of New JerseySlow-degrading polymers comprising salicylic acid for undelayed and sustained drug delivery
US9782432B2 (en)2012-10-252017-10-10Rutgers, The State University Of New JerseyPolymers and methods thereof for wound healing
US10092537B2 (en)2013-04-152018-10-09Renascience Co., Ltd.Use for PAI-1 inhibitor
US9862672B2 (en)2013-05-292018-01-09Rutgers, The State University Of New JerseyAntioxidant-based poly(anhydride-esters)
US10023521B2 (en)2014-06-132018-07-17Rutgers, The State University Of New JerseyProcess and intermediates for preparing poly(anhydride-esters)
US10543162B2 (en)2015-04-102020-01-28Rutgers, The State University Of New JerseyKojic acid polymers

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