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JPS56100714A - Pharmaceutical adhering to oral mucous membrane or nasal mucous membrane - Google Patents

Pharmaceutical adhering to oral mucous membrane or nasal mucous membrane

Info

Publication number
JPS56100714A
JPS56100714AJP252280AJP252280AJPS56100714AJP S56100714 AJPS56100714 AJP S56100714AJP 252280 AJP252280 AJP 252280AJP 252280 AJP252280 AJP 252280AJP S56100714 AJPS56100714 AJP S56100714A
Authority
JP
Japan
Prior art keywords
mucous membrane
pharmaceutical
adhering
drug
oral
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP252280A
Other languages
Japanese (ja)
Other versions
JPS6323964B2 (en
Inventor
Tsuneji Nagai
Ryoji Machida
Naoki Nanbu
Masami Ishida
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Teijin Ltd
Original Assignee
Teijin Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teijin LtdfiledCriticalTeijin Ltd
Priority to JP252280ApriorityCriticalpatent/JPS56100714A/en
Publication of JPS56100714ApublicationCriticalpatent/JPS56100714A/en
Publication of JPS6323964B2publicationCriticalpatent/JPS6323964B2/ja
Grantedlegal-statusCriticalCurrent

Links

Landscapes

Abstract

PURPOSE: The titled pharmaceutical, capable of being absorbed from the mucous membrane well, and prepared by placing a drug layer containing particularly a drug which will not be absorbed orally in a coating layer adhering to the mucous membrane unevenly.
CONSTITUTION: A pharmaceutical adhering to the oral or nasal mucous membrane prepared by placing a drug layer consisting of an ointment base containing a drug, particularly insulin which can be administered only by the injection at present and a surfactant unevenly in a coating layer adhering to the mucous membrane, and consisting of a cellulose ether and/or an acrylic acid polymer or a salt thereof, e.g. hydroxypropyl cellulose and carbopol in a 1:2 mixture base. The pharmaceutical adhered to the oral or nasal mucous membrane permits the efficient absorption of insulin from the mucous membrane with a high absorption efficiency for a long time without using injection giving pain to a patient.
COPYRIGHT: (C)1981,JPO&Japio
JP252280A1980-01-161980-01-16Pharmaceutical adhering to oral mucous membrane or nasal mucous membraneGrantedJPS56100714A (en)

Priority Applications (1)

Application NumberPriority DateFiling DateTitle
JP252280AJPS56100714A (en)1980-01-161980-01-16Pharmaceutical adhering to oral mucous membrane or nasal mucous membrane

Applications Claiming Priority (1)

Application NumberPriority DateFiling DateTitle
JP252280AJPS56100714A (en)1980-01-161980-01-16Pharmaceutical adhering to oral mucous membrane or nasal mucous membrane

Publications (2)

Publication NumberPublication Date
JPS56100714Atrue JPS56100714A (en)1981-08-12
JPS6323964B2 JPS6323964B2 (en)1988-05-18

Family

ID=11531701

Family Applications (1)

Application NumberTitlePriority DateFiling Date
JP252280AGrantedJPS56100714A (en)1980-01-161980-01-16Pharmaceutical adhering to oral mucous membrane or nasal mucous membrane

Country Status (1)

CountryLink
JP (1)JPS56100714A (en)

Cited By (55)

* Cited by examiner, † Cited by third party
Publication numberPriority datePublication dateAssigneeTitle
JPS5989619A (en)*1982-10-051984-05-23サンド・アクチエンゲゼルシヤフト Calcitonin composition and its uses
JPS59232552A (en)*1983-06-161984-12-27日東電工株式会社 mucosal bandage
JPS59232553A (en)*1983-06-161984-12-27日東電工株式会社 mucosal bandage
US4517173A (en)*1980-09-261985-05-14Nippon Soda Co. Ltd.Mucous membrane-adhering film preparation and process for its preparation
US4569837A (en)*1983-06-011986-02-11Teijin LimitedPharmaceutical preparation for remedy of periodontal disease and process for production thereof
US4572832A (en)*1982-10-071986-02-25Grelan Pharmaceutical Co., Ltd.Soft buccal
JPS61282320A (en)*1985-06-041986-12-12サンド・アクチエンゲゼルシヤフトNasal medicinal composition
JPS63310818A (en)*1987-06-121988-12-19Sato Seiyaku KkSheet preparation to be applied to oral mucosa
JPH01279839A (en)*1988-04-301989-11-10Nitto Denko Corp Water-soluble bioactive protein preparation
JPH02262526A (en)*1982-10-051990-10-25Sandoz Ag Calcitonin composition and its uses
US5122127A (en)*1985-05-011992-06-16University Of UtahApparatus and methods for use in administering medicaments by direct medicament contact to mucosal tissues
US5132114A (en)*1985-05-011992-07-21University Of Utah Research FoundationCompositions and methods of manufacture of compressed powder medicaments
US5364634A (en)*1991-11-081994-11-15Southwest Research InstituteControlled-release PH sensitive capsule and adhesive system and method
US5800832A (en)*1996-10-181998-09-01Virotex CorporationBioerodable film for delivery of pharmaceutical compounds to mucosal surfaces
US5955097A (en)*1996-10-181999-09-21Virotex CorporationPharmaceutical preparation applicable to mucosal surfaces and body tissues
WO2000001416A1 (en)*1998-07-072000-01-13Yissum Research Developing Company Of The Hebrew University Of JerusalemPharmaceutical compositions containing low-melting waxes
US6103266A (en)*1998-04-222000-08-15Tapolsky; Gilles H.Pharmaceutical gel preparation applicable to mucosal surfaces and body tissues
JP2001131057A (en)*1999-08-262001-05-15Takeda Chem Ind Ltd Nasal mucosa attachment matrix
EP1123696A4 (en)*1998-09-252002-02-06Kao CorpCompositions for oral cavity
US6432415B1 (en)1999-12-172002-08-13Axrix Laboratories, Inc.Pharmaceutical gel and aerosol formulations and methods to administer the same to skin and mucosal surfaces
JP2009535304A (en)*2006-04-132009-10-01オラヘルス コーポレーション Mouth patch containing salt of glycyrrhetinic acid which is water soluble at mouth temperature
US8173113B1 (en)1989-11-032012-05-083M Innovative Properties CompanyBioadhesive composition and patch
US8900498B2 (en)2001-10-122014-12-02Monosol Rx, LlcProcess for manufacturing a resulting multi-layer pharmaceutical film
US8900497B2 (en)2001-10-122014-12-02Monosol Rx, LlcProcess for making a film having a substantially uniform distribution of components
US8906277B2 (en)2001-10-122014-12-09Monosol Rx, LlcProcess for manufacturing a resulting pharmaceutical film
JP2015519403A (en)*2012-06-142015-07-09エントレガ,インコーポレイテッド Mucoadhesive devices for active agent delivery
US9108340B2 (en)2001-10-122015-08-18Monosol Rx, LlcProcess for manufacturing a resulting multi-layer pharmaceutical film
US9597288B2 (en)2006-07-212017-03-21Biodelivery Sciences International, Inc.Transmucosal delivery devices with enhanced uptake
US9855221B2 (en)2001-10-122018-01-02Monosol Rx, LlcUniform films for rapid-dissolve dosage form incorporating anti-tacking compositions
US9901539B2 (en)2011-12-212018-02-27Biodelivery Sciences International, Inc.Transmucosal drug delivery devices for use in chronic pain relief
US9931305B2 (en)2001-10-122018-04-03Monosol Rx, LlcUniform films for rapid dissolve dosage form incorporating taste-masking compositions
US10272607B2 (en)2010-10-222019-04-30Aquestive Therapeutics, Inc.Manufacturing of small film strips
US10285910B2 (en)2001-10-122019-05-14Aquestive Therapeutics, Inc.Sublingual and buccal film compositions
US10821074B2 (en)2009-08-072020-11-03Aquestive Therapeutics, Inc.Sublingual and buccal film compositions
US11077068B2 (en)2001-10-122021-08-03Aquestive Therapeutics, Inc.Uniform films for rapid-dissolve dosage form incorporating anti-tacking compositions
US11191737B2 (en)2016-05-052021-12-07Aquestive Therapeutics, Inc.Enhanced delivery epinephrine compositions
US11207805B2 (en)2001-10-122021-12-28Aquestive Therapeutics, Inc.Process for manufacturing a resulting pharmaceutical film
US11273131B2 (en)2016-05-052022-03-15Aquestive Therapeutics, Inc.Pharmaceutical compositions with enhanced permeation
JP2022166793A (en)*2021-04-212022-11-02順也 藤森Phytochemical composition
US11826388B2 (en)2013-12-202023-11-28Seed Health, Inc.Topical application of Lactobacillus crispatus to ameliorate barrier damage and inflammation
US11833177B2 (en)2013-12-202023-12-05Seed Health, Inc.Probiotic to enhance an individual's skin microbiome
US11839632B2 (en)2013-12-202023-12-12Seed Health, Inc.Topical application of CRISPR-modified bacteria to treat acne vulgaris
US11951140B2 (en)2011-02-042024-04-09Seed Health, Inc.Modulation of an individual's gut microbiome to address osteoporosis and bone disease
US11951139B2 (en)2015-11-302024-04-09Seed Health, Inc.Method and system for reducing the likelihood of osteoporosis
US11969445B2 (en)2013-12-202024-04-30Seed Health, Inc.Probiotic composition and method for controlling excess weight, obesity, NAFLD and NASH
US11980643B2 (en)2013-12-202024-05-14Seed Health, Inc.Method and system to modify an individual's gut-brain axis to provide neurocognitive protection
US11998479B2 (en)2011-02-042024-06-04Seed Health, Inc.Method and system for addressing adverse effects on the oral microbiome and restoring gingival health caused by sodium lauryl sulphate exposure
US11998574B2 (en)2013-12-202024-06-04Seed Health, Inc.Method and system for modulating an individual's skin microbiome
US12005085B2 (en)2013-12-202024-06-11Seed Health, Inc.Probiotic method and composition for maintaining a healthy vaginal microbiome
US12246043B2 (en)2013-12-202025-03-11Seed Health, Inc.Topical application to treat acne vulgaris
US12257272B2 (en)2015-12-242025-03-25Seed Health, Inc.Method and system for reducing the likelihood of developing depression in an individual
US12279989B2 (en)2011-02-042025-04-22Seed Health, Inc.Method and system for increasing beneficial bacteria and decreasing pathogenic bacteria in the oral cavity
US12329783B2 (en)2013-12-202025-06-17Seed Health, Inc.Method and system to improve the health of a person's skin microbiome
US12427121B2 (en)2016-05-052025-09-30Aquestive Therapeutics, Inc.Enhanced delivery epinephrine compositions
US12433850B2 (en)2016-05-052025-10-07Aquestive Therapeutics, Inc.Enhanced delivery epinephrine and prodrug compositions

Cited By (66)

* Cited by examiner, † Cited by third party
Publication numberPriority datePublication dateAssigneeTitle
US4517173A (en)*1980-09-261985-05-14Nippon Soda Co. Ltd.Mucous membrane-adhering film preparation and process for its preparation
JPH02262526A (en)*1982-10-051990-10-25Sandoz Ag Calcitonin composition and its uses
JPS5989619A (en)*1982-10-051984-05-23サンド・アクチエンゲゼルシヤフト Calcitonin composition and its uses
US4572832A (en)*1982-10-071986-02-25Grelan Pharmaceutical Co., Ltd.Soft buccal
US4569837A (en)*1983-06-011986-02-11Teijin LimitedPharmaceutical preparation for remedy of periodontal disease and process for production thereof
JPS59232552A (en)*1983-06-161984-12-27日東電工株式会社 mucosal bandage
JPS59232553A (en)*1983-06-161984-12-27日東電工株式会社 mucosal bandage
US5122127A (en)*1985-05-011992-06-16University Of UtahApparatus and methods for use in administering medicaments by direct medicament contact to mucosal tissues
US5132114A (en)*1985-05-011992-07-21University Of Utah Research FoundationCompositions and methods of manufacture of compressed powder medicaments
JPS61282320A (en)*1985-06-041986-12-12サンド・アクチエンゲゼルシヤフトNasal medicinal composition
JPS63310818A (en)*1987-06-121988-12-19Sato Seiyaku KkSheet preparation to be applied to oral mucosa
JPH01279839A (en)*1988-04-301989-11-10Nitto Denko Corp Water-soluble bioactive protein preparation
US8173113B1 (en)1989-11-032012-05-083M Innovative Properties CompanyBioadhesive composition and patch
US5364634A (en)*1991-11-081994-11-15Southwest Research InstituteControlled-release PH sensitive capsule and adhesive system and method
US5955097A (en)*1996-10-181999-09-21Virotex CorporationPharmaceutical preparation applicable to mucosal surfaces and body tissues
US6159498A (en)*1996-10-182000-12-12Virotex CorporationBioerodable film for delivery of pharmaceutical compounds of mucosal surfaces
US5800832A (en)*1996-10-181998-09-01Virotex CorporationBioerodable film for delivery of pharmaceutical compounds to mucosal surfaces
US6290984B1 (en)1996-10-182001-09-18Virotex CorporationPharmaceutical preparation applicable to mucosal surfaces and body tissues
US7579019B2 (en)1996-10-182009-08-25Arius Two, Inc.Pharmaceutical carrier device suitable for delivery of pharmaceutical compounds to mucosal surfaces
US6103266A (en)*1998-04-222000-08-15Tapolsky; Gilles H.Pharmaceutical gel preparation applicable to mucosal surfaces and body tissues
WO2000001416A1 (en)*1998-07-072000-01-13Yissum Research Developing Company Of The Hebrew University Of JerusalemPharmaceutical compositions containing low-melting waxes
EP1123696A4 (en)*1998-09-252002-02-06Kao CorpCompositions for oral cavity
JP2001131057A (en)*1999-08-262001-05-15Takeda Chem Ind Ltd Nasal mucosa attachment matrix
US6432415B1 (en)1999-12-172002-08-13Axrix Laboratories, Inc.Pharmaceutical gel and aerosol formulations and methods to administer the same to skin and mucosal surfaces
US9108340B2 (en)2001-10-122015-08-18Monosol Rx, LlcProcess for manufacturing a resulting multi-layer pharmaceutical film
US8900498B2 (en)2001-10-122014-12-02Monosol Rx, LlcProcess for manufacturing a resulting multi-layer pharmaceutical film
US8900497B2 (en)2001-10-122014-12-02Monosol Rx, LlcProcess for making a film having a substantially uniform distribution of components
US8906277B2 (en)2001-10-122014-12-09Monosol Rx, LlcProcess for manufacturing a resulting pharmaceutical film
US11207805B2 (en)2001-10-122021-12-28Aquestive Therapeutics, Inc.Process for manufacturing a resulting pharmaceutical film
US11077068B2 (en)2001-10-122021-08-03Aquestive Therapeutics, Inc.Uniform films for rapid-dissolve dosage form incorporating anti-tacking compositions
US10285910B2 (en)2001-10-122019-05-14Aquestive Therapeutics, Inc.Sublingual and buccal film compositions
US9855221B2 (en)2001-10-122018-01-02Monosol Rx, LlcUniform films for rapid-dissolve dosage form incorporating anti-tacking compositions
US10888499B2 (en)2001-10-122021-01-12Aquestive Therapeutics, Inc.Thin film with non-self-aggregating uniform heterogeneity and drug delivery systems made therefrom
US9931305B2 (en)2001-10-122018-04-03Monosol Rx, LlcUniform films for rapid dissolve dosage form incorporating taste-masking compositions
US10111810B2 (en)2002-04-112018-10-30Aquestive Therapeutics, Inc.Thin film with non-self-aggregating uniform heterogeneity and drug delivery systems made therefrom
JP2009535304A (en)*2006-04-132009-10-01オラヘルス コーポレーション Mouth patch containing salt of glycyrrhetinic acid which is water soluble at mouth temperature
US9655843B2 (en)2006-07-212017-05-23Biodelivery Sciences International, Inc.Transmucosal delivery devices with enhanced uptake
US9597288B2 (en)2006-07-212017-03-21Biodelivery Sciences International, Inc.Transmucosal delivery devices with enhanced uptake
US10821074B2 (en)2009-08-072020-11-03Aquestive Therapeutics, Inc.Sublingual and buccal film compositions
US10940626B2 (en)2010-10-222021-03-09Aquestive Therapeutics, Inc.Manufacturing of small film strips
US10272607B2 (en)2010-10-222019-04-30Aquestive Therapeutics, Inc.Manufacturing of small film strips
US12279989B2 (en)2011-02-042025-04-22Seed Health, Inc.Method and system for increasing beneficial bacteria and decreasing pathogenic bacteria in the oral cavity
US11998479B2 (en)2011-02-042024-06-04Seed Health, Inc.Method and system for addressing adverse effects on the oral microbiome and restoring gingival health caused by sodium lauryl sulphate exposure
US11951140B2 (en)2011-02-042024-04-09Seed Health, Inc.Modulation of an individual's gut microbiome to address osteoporosis and bone disease
US9901539B2 (en)2011-12-212018-02-27Biodelivery Sciences International, Inc.Transmucosal drug delivery devices for use in chronic pain relief
JP2015519403A (en)*2012-06-142015-07-09エントレガ,インコーポレイテッド Mucoadhesive devices for active agent delivery
US11833177B2 (en)2013-12-202023-12-05Seed Health, Inc.Probiotic to enhance an individual's skin microbiome
US11826388B2 (en)2013-12-202023-11-28Seed Health, Inc.Topical application of Lactobacillus crispatus to ameliorate barrier damage and inflammation
US11839632B2 (en)2013-12-202023-12-12Seed Health, Inc.Topical application of CRISPR-modified bacteria to treat acne vulgaris
US12318414B2 (en)2013-12-202025-06-03Seed Health, Inc.Method and system to modify an individual's gut-brain axis to provide neurocognitive protection
US11969445B2 (en)2013-12-202024-04-30Seed Health, Inc.Probiotic composition and method for controlling excess weight, obesity, NAFLD and NASH
US11980643B2 (en)2013-12-202024-05-14Seed Health, Inc.Method and system to modify an individual's gut-brain axis to provide neurocognitive protection
US12329783B2 (en)2013-12-202025-06-17Seed Health, Inc.Method and system to improve the health of a person's skin microbiome
US11998574B2 (en)2013-12-202024-06-04Seed Health, Inc.Method and system for modulating an individual's skin microbiome
US12005085B2 (en)2013-12-202024-06-11Seed Health, Inc.Probiotic method and composition for maintaining a healthy vaginal microbiome
US12318411B2 (en)2013-12-202025-06-03Seed Health, Inc.Probiotic method and composition for maintaining a healthy vaginal microbiome
US12246043B2 (en)2013-12-202025-03-11Seed Health, Inc.Topical application to treat acne vulgaris
US12357662B2 (en)2013-12-202025-07-15Seed Health, Inc.Modulation of an individual's gut microbiome to address osteoporosis and bone disease
US11951139B2 (en)2015-11-302024-04-09Seed Health, Inc.Method and system for reducing the likelihood of osteoporosis
US12257272B2 (en)2015-12-242025-03-25Seed Health, Inc.Method and system for reducing the likelihood of developing depression in an individual
US12023309B2 (en)2016-05-052024-07-02Aquestive Therapeutics, Inc.Enhanced delivery epinephrine compositions
US11273131B2 (en)2016-05-052022-03-15Aquestive Therapeutics, Inc.Pharmaceutical compositions with enhanced permeation
US11191737B2 (en)2016-05-052021-12-07Aquestive Therapeutics, Inc.Enhanced delivery epinephrine compositions
US12427121B2 (en)2016-05-052025-09-30Aquestive Therapeutics, Inc.Enhanced delivery epinephrine compositions
US12433850B2 (en)2016-05-052025-10-07Aquestive Therapeutics, Inc.Enhanced delivery epinephrine and prodrug compositions
JP2022166793A (en)*2021-04-212022-11-02順也 藤森Phytochemical composition

Also Published As

Publication numberPublication date
JPS6323964B2 (en)1988-05-18

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