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JPS5520747A - Antidepressant - Google Patents

Antidepressant

Info

Publication number
JPS5520747A
JPS5520747AJP9428778AJP9428778AJPS5520747AJP S5520747 AJPS5520747 AJP S5520747AJP 9428778 AJP9428778 AJP 9428778AJP 9428778 AJP9428778 AJP 9428778AJP S5520747 AJPS5520747 AJP S5520747A
Authority
JP
Japan
Prior art keywords
dops
antidepressant
threo
erythro
dihydroxyphenyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP9428778A
Other languages
Japanese (ja)
Inventor
Takemoto Honma
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sumitomo Chemical Co Ltd
Original Assignee
Sumitomo Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sumitomo Chemical Co LtdfiledCriticalSumitomo Chemical Co Ltd
Priority to JP9428778ApriorityCriticalpatent/JPS5520747A/en
Publication of JPS5520747ApublicationCriticalpatent/JPS5520747A/en
Pendinglegal-statusCriticalCurrent

Links

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Abstract

PURPOSE: An antidepressant containing 3-(3,4-dihydroxyphenyl)-serine as the effective ingredient that has different action mechanism from tricycle antidepressant.
CONSTITUTION: Said antidepressant contains 3-(3,4-dihydroxyphenyl)-serine or its salt (DOPS) as the effective ingredient. DOPS has four optical isomers of L-threo- DOPS, D-threo-DOPS, L-erythro-DOPS and D-erythro-DOPS, of which L-threo- DOPS is the most effective. DOPS inhibits the hypothermy of mouse caused by reserpine and tetrabenazine, thus showing antidepressant activity.
COPYRIGHT: (C)1980,JPO&Japio
JP9428778A1978-08-011978-08-01AntidepressantPendingJPS5520747A (en)

Priority Applications (1)

Application NumberPriority DateFiling DateTitle
JP9428778AJPS5520747A (en)1978-08-011978-08-01Antidepressant

Applications Claiming Priority (1)

Application NumberPriority DateFiling DateTitle
JP9428778AJPS5520747A (en)1978-08-011978-08-01Antidepressant

Publications (1)

Publication NumberPublication Date
JPS5520747Atrue JPS5520747A (en)1980-02-14

Family

ID=14106035

Family Applications (1)

Application NumberTitlePriority DateFiling Date
JP9428778APendingJPS5520747A (en)1978-08-011978-08-01Antidepressant

Country Status (1)

CountryLink
JP (1)JPS5520747A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication numberPriority datePublication dateAssigneeTitle
JPS6067420A (en)*1983-09-221985-04-17Sumitomo Chem Co Ltd psychomotor arousal inhibitor
WO1999052519A3 (en)*1998-04-141999-12-02Gen Hospital CorpMethods for treating neuropsychiatric disorders

Citations (1)

* Cited by examiner, † Cited by third party
Publication numberPriority datePublication dateAssigneeTitle
JPS5049252A (en)*1973-08-221975-05-01

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication numberPriority datePublication dateAssigneeTitle
JPS5049252A (en)*1973-08-221975-05-01

Cited By (6)

* Cited by examiner, † Cited by third party
Publication numberPriority datePublication dateAssigneeTitle
JPS6067420A (en)*1983-09-221985-04-17Sumitomo Chem Co Ltd psychomotor arousal inhibitor
WO1999052519A3 (en)*1998-04-141999-12-02Gen Hospital CorpMethods for treating neuropsychiatric disorders
US6228875B1 (en)1998-04-142001-05-08The General Hospital CorporationMethods for treating neuropsychiatric disorders
US6667297B2 (en)1998-04-142003-12-23The General Hospital CorporationMethods for treating neuropsychiatric disorders
US6974821B2 (en)1998-04-142005-12-13The General Hospital CorporationMethods for treating neuropsychiatric disorders
US7704978B2 (en)1998-04-142010-04-27The General Hospital CorporationMethods for treating neuropsychiatric disorders

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