【０００１】[0001]
【産業上の利用分野】本発明は、血液あるいは唾液等の
試料液中の所定の成分を測定する液体の成分測定装置に
関するもので、特に、測定時に、その測定装置の反応試
薬層に規定量の試料液が点着されているか否かを検出
し、点着量不足による誤測定の発生を除去せんとするも
のである。BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a liquid component measuring device for measuring a predetermined component in a sample liquid such as blood or saliva, and particularly, at the time of measurement, a prescribed amount in a reaction reagent layer of the measuring device. It is intended to detect whether or not the sample liquid is spotted and eliminate the occurrence of erroneous measurement due to insufficient spotted amount.
【０００２】[0002]
【従来の技術】従来より、試料液中の成分測定装置とし
て、例えば血液中の所定の成分との反応により発生する
酸化電流を測定することにより、血糖値等を求めるもの
がある。2. Description of the Related Art Conventionally, as a component measuring device in a sample liquid, there is a device for determining a blood glucose level by measuring an oxidizing current generated by a reaction with a predetermined component in blood, for example.
【０００３】図２はそのような従来の血液中の成分測定
装置の分解斜視図であり、１，２は互いに近接離間した
状態で基台４上に配置された一対の測定電極であり、そ
の上には前記両測定電極１，２を一体的に覆うように反
応試薬層５が形成されている。そして、１a ，２a はそ
れぞれ前記測定電極１，２に接続されたリード端子であ
る。FIG. 2 is an exploded perspective view of such a conventional device for measuring the components in blood. Reference numerals 1 and 2 denote a pair of measurement electrodes arranged on a base 4 in a state of being closely spaced from each other. A reaction reagent layer 5 is formed on the upper side so as to integrally cover both of the measurement electrodes 1 and 2. 1a and 2a are lead terminals connected to the measurement electrodes 1 and 2, respectively.
【０００４】７は前記リード端子１a ，２a の端部が露
出されるように、前記基台４を覆うカバーであり、その
一端部には試料液を前記反応試薬層５に導くための試料
液注入口８が形成されているとともに、その注入口８に
続いて形成された吸引溝８aの終端部には試料液の吸入
を助長するための空気逃げ孔６が形成されている。Reference numeral 7 is a cover for covering the base 4 so that the ends of the lead terminals 1a and 2a are exposed, and one end of the cover 7 is a sample liquid for guiding the sample liquid to the reaction reagent layer 5. An inlet 8 is formed, and an air escape hole 6 for promoting suction of the sample liquid is formed at the end of a suction groove 8a formed subsequent to the inlet 8.
【０００５】すなわち、前記注入口８の先端に測定すべ
き試料液を付着させると、その試料液は毛細管現象によ
り吸引溝８a に吸入され、反応試薬層５まで導かれ、そ
の反応試薬層５と反応し、酸化電流を発生する。この酸
化電流量を、リード端子１a，２a に接続された電流測
定手段（図示せず）で計測することにより、試料液の成
分を測定するものである。That is, when the sample liquid to be measured is attached to the tip of the injection port 8, the sample liquid is sucked into the suction groove 8a by the capillary phenomenon, is guided to the reaction reagent layer 5, and is connected to the reaction reagent layer 5. Reacts and generates an oxidation current. The component of the sample liquid is measured by measuring the amount of this oxidation current by a current measuring means (not shown) connected to the lead terminals 1a and 2a.
【０００６】[0006]
【発明が解決しようとする課題】しかしながら上記従来
の測定装置においては、吸引溝８を経由して反応試薬層
５に点着する試料液量が適正量より少ない場合でも、計
測を実行し真値より低い数値を示すことがあるため、点
着された試料液量を測定者が目視等により確認し適正判
断をする必要があった。 本発明は、反応試薬層に点着
する血液量の適正を自動的に検知し、測定者の目視等に
よる判断を回避し点着量不足による測定誤差を無くせん
とするものである。However, in the above conventional measuring device, even if the amount of the sample liquid spotted on the reaction reagent layer 5 via the suction groove 8 is smaller than the proper amount, the measurement is performed and the true value is obtained. Since it may show a lower numerical value, it is necessary for the measurer to visually check the amount of the sample liquid spotted and make an appropriate judgment. The present invention automatically detects the adequacy of the amount of blood spotted on the reaction reagent layer, avoids the judgment by the operator's visual observation, etc., and eliminates the measurement error due to insufficient spotted amount.
【０００７】[0007]
【課題を解決するための手段】上記課題を解決するため
の本発明の液体の成分測定装置は、試料液注入口に対し
て測定用電極よりさらに離れた位置で、前記の一対の測
定用電極の一つに近接し、かつ、前記試薬層で一体的に
覆われた検出用電極を新たに設け、その検出用電極と前
記測定用電極の一つとの間に流れる電流値により、前記
試料液の前記試薬層への点着量が規定量以上であるか否
かを検出することを特徴とするものである。A liquid component measuring apparatus according to the present invention for solving the above-mentioned problems comprises a pair of measuring electrodes at a position farther from a measuring electrode with respect to a sample liquid inlet. One of the above-mentioned sample liquids is newly provided with a detection electrode which is close to one of the above and is integrally covered with the reagent layer, and the sample liquid is caused by the current value flowing between the detection electrode and one of the measurement electrodes. It is characterized in that whether or not the spotted amount on the reagent layer is not less than a specified amount is detected.
【０００８】[0008]
【作用】上記構成によれば、検出用電極は、試料液注入
口に対して測定用電極より離れた位置に設置されている
ため、すなわち、反応試薬層の中でも試料液の点着量不
足の影響を受けやすい場所に配置しているため、試料液
量が適正量に達していない場合は、検出用電極に試料液
が点着されず酸化電流が発生しないこととなる。従っ
て、この検出用電極に試料液が点着されて発生する酸化
電流の有無を検出した後に、測定を開始するようにすれ
ば、反応試薬層に点着する試料液量が適正量に満たない
場合の計測を回避することができ、試料液の点着量が測
定精度を確保するに至らない場合に発生する測定誤差が
なくなる。According to the above construction, the detection electrode is installed at a position distant from the measurement electrode with respect to the sample solution injection port, that is, the spotted amount of the sample solution is insufficient in the reaction reagent layer. Since the sample liquid is placed in a place where it is easily affected, if the amount of the sample liquid does not reach the appropriate amount, the sample liquid is not spotted on the detection electrode and no oxidation current is generated. Therefore, if the measurement is started after detecting the presence or absence of an oxidation current generated by the sample liquid being spotted on the detection electrode, the amount of the sample liquid spotted on the reaction reagent layer is less than an appropriate amount. In this case, the measurement can be avoided, and the measurement error that occurs when the spotted amount of the sample liquid does not ensure the measurement accuracy is eliminated.
【０００９】[0009]
【実施例】以下本発明の実施例について図面を参照して
説明する。図１は本発明の一実施例における液体の成分
測定装置の構造を示す分解斜視図であり、従来と同様の
構成部分については同符号を付して説明を略し、異なる
部分についてのみ説明する。Embodiments of the present invention will be described below with reference to the drawings. FIG. 1 is an exploded perspective view showing the structure of a liquid component measuring apparatus according to an embodiment of the present invention. The same components as those of the conventional one are designated by the same reference numerals, and the description thereof will be omitted. Only different portions will be described.
【００１０】図１において、従来の液体の成分測定装置
の構造と異なるところは、一対の測定電極１，２の他に
新たに検出用電極３を配置したことである。この検出用
電極３は、試料液注入口８に対して測定用電極１，２よ
りも奥まった位置で、測定電極１に近接して設けられて
いる。なお、３a は検出用電極３のリード線である。そ
して、この一対の測定電極１，２と検出用電極３を一体
的に覆うように反応試薬層５が形成されている。なお、
検出用電極３と測定電極１及び対電極２の平面距離は
０，０５ｍｍ〜０，３５ｍｍとし、検出用電極３の面積
は、測定電極１の１／５〜１／２の面積とする。また検
出用電極３の形状は長方形、正方形、三角形、菱型、楕
円形、円形の何れでもよい。In FIG. 1, the difference from the structure of the conventional liquid component measuring apparatus is that a detection electrode 3 is newly arranged in addition to the pair of measurement electrodes 1 and 2. The detection electrode 3 is provided closer to the measurement electrode 1 at a position deeper than the measurement electrodes 1 and 2 with respect to the sample liquid injection port 8. In addition, 3a is a lead wire of the detection electrode 3. A reaction reagent layer 5 is formed so as to integrally cover the pair of measurement electrodes 1 and 2 and the detection electrode 3. In addition,
The plane distance between the detection electrode 3 and the measurement electrode 1 and the counter electrode 2 is 0.05 mm to 0.35 mm, and the area of the detection electrode 3 is 1/5 to 1/2 of that of the measurement electrode 1. The shape of the detection electrode 3 may be any of rectangle, square, triangle, rhombus, ellipse, and circle.
【００１１】以上の構成によれば、測定時に試料液注入
口８より充分な試料液が吸入されなかった場合には、当
然ながら試料液注入口８の奥まった部分に配置されてい
る検出用電極３の近傍には試料液が到達されていないた
め、この検出用電極３からは酸化電流の検出はなされな
いものである。すなわち、この検出用電極３からの酸化
電流の有無により、必要な試料液の量の有無が推測され
るものである。According to the above construction, when a sufficient amount of the sample liquid is not sucked from the sample liquid injection port 8 at the time of measurement, the detection electrode arranged in the deep portion of the sample liquid injection port 8 is naturally used. Since the sample liquid has not reached the vicinity of 3, the detection electrode 3 cannot detect the oxidation current. That is, the presence / absence of the required amount of the sample liquid is estimated by the presence / absence of the oxidation current from the detection electrode 3.
【００１２】[0012]
【発明の効果】上述のように本発明の液体の成分測定装
置によれば、試料液注入口より供給され、反応試薬層に
点着される液体が成分の測定に必要な適正量到達したこ
とを検出でき、不十分な液体量により、誤測定をするこ
とは、なくなるものである。As described above, according to the liquid component measuring apparatus of the present invention, the liquid supplied from the sample liquid inlet and spotted on the reaction reagent layer has reached an appropriate amount necessary for measuring the component. Erroneous measurement due to insufficient liquid amount can be detected.
【図１】本発明の液体の成分測定装置の一実施例を示す
分解斜視図FIG. 1 is an exploded perspective view showing an embodiment of a liquid component measuring apparatus of the present invention.
【図２】従来の液体の成分測定装置の分解斜視図FIG. 2 is an exploded perspective view of a conventional liquid component measuring device.
１、２ 測定電極 ３ 検出用電極 ４ 基台 ５ 反応試薬層 ６ 空気逃げ孔 ８ 試料液注入口 1, 2 Measurement electrode 3 Detection electrode 4 Base 5 Reaction reagent layer 6 Air escape hole 8 Sample solution inlet
───────────────────────────────────────────────────── フロントページの続き (72)発明者 宮崎 正次 香川県高松市寿町２丁目２番10号 松下寿 電子工業株式会社内 ─────────────────────────────────────────────────── ─── Continuation of the front page (72) Inventor Masatsugu Miyazaki 2-2-10, Kotobukicho, Takamatsu-shi, Kagawa Matsushita Kotobushiki Kogyo Co., Ltd.
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP25607692AJP3189416B2 (en) | 1992-09-25 | 1992-09-25 | Liquid component measuring device |
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP25607692AJP3189416B2 (en) | 1992-09-25 | 1992-09-25 | Liquid component measuring device |
| Publication Number | Publication Date |
|---|---|
| JPH06109688Atrue JPH06109688A (en) | 1994-04-22 |
| JP3189416B2 JP3189416B2 (en) | 2001-07-16 |
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP25607692AExpired - LifetimeJP3189416B2 (en) | 1992-09-25 | 1992-09-25 | Liquid component measuring device |
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| WO2011031751A1 (en)* | 2009-09-08 | 2011-03-17 | Bayer Healthcare Llc | Electrochemical test sensor |
| US10585059B2 (en) | 2009-09-08 | 2020-03-10 | Ascensia Diabetes Care Holdings Ag | Electrochemical test sensor |
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