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IN2014DN09352A - - Google Patents

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Publication number
IN2014DN09352A
IN2014DN09352AIN9352DEN2014AIN2014DN09352AIN 2014DN09352 AIN2014DN09352 AIN 2014DN09352AIN 9352DEN2014 AIN9352DEN2014 AIN 9352DEN2014AIN 2014DN09352 AIN2014DN09352 AIN 2014DN09352A
Authority
IN
India
Prior art keywords
compounds
disorders
substituents
useful
formula
Prior art date
Application number
Inventor
Stephen Deems Gabriel
Matthew Michael Hamilton
Yimin Qian
Achyutharao Sidduri
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filedlitigationCriticalhttps://patents.darts-ip.com/?family=48628669&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IN2014DN09352(A)"Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Hoffmann La RochefiledCriticalHoffmann La Roche
Publication of IN2014DN09352ApublicationCriticalpatent/IN2014DN09352A/en

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Abstract

Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof wherein the substituents are as those disclosed in the specification. These compounds and the pharmaceutical compositions containing them are useful for the treatment of inflammatory diseases and disorders such as for example pulmonary fibrosis.
IN9352DEN20142012-06-202013-06-17IN2014DN09352A (en)

Applications Claiming Priority (2)

Application NumberPriority DateFiling DateTitle
US201261661953P2012-06-202012-06-20
PCT/EP2013/062463WO2013189865A1 (en)2012-06-202013-06-17N-aryltriazole compounds as lpar antagonists

Publications (1)

Publication NumberPublication Date
IN2014DN09352Atrue IN2014DN09352A (en)2015-07-17

Family

ID=48628669

Family Applications (1)

Application NumberTitlePriority DateFiling Date
IN9352DEN2014IN2014DN09352A (en)2012-06-202013-06-17

Country Status (22)

CountryLink
US (1)US20150133512A1 (en)
EP (1)EP2864301A1 (en)
JP (1)JP2015520203A (en)
KR (1)KR20150011389A (en)
CN (1)CN104395299A (en)
AU (1)AU2013279513A1 (en)
BR (1)BR112014030674A2 (en)
CA (1)CA2869564A1 (en)
CL (1)CL2014003241A1 (en)
CO (1)CO7131357A2 (en)
EA (1)EA201492281A1 (en)
HK (1)HK1206339A1 (en)
IL (1)IL236087A0 (en)
IN (1)IN2014DN09352A (en)
MA (1)MA37762B1 (en)
MX (1)MX2014014711A (en)
PE (1)PE20142305A1 (en)
PH (1)PH12014502363A1 (en)
SG (1)SG11201407228PA (en)
UA (1)UA110310C2 (en)
WO (1)WO2013189865A1 (en)
ZA (1)ZA201408167B (en)

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JP2014525932A (en)2011-08-152014-10-02インターミューン， インコーポレイテッド Lysophosphatide acid receptor antagonist
TW201437200A (en)*2013-01-152014-10-01Intermune IncLysophosphatidic acid receptor antagonists
MX382748B (en)2013-03-152025-03-13Epigen Biosciences Inc HETEROCYCLIC COMPOUNDS USEFUL FOR THE TREATMENT OF A DISEASE.
UY36060A (en)2014-04-022015-10-30Bayer Pharma AG AZOL COMPOUNDS REPLACED WITH AMIDA
KR102433588B1 (en)2014-06-272022-08-19우베 가부시키가이샤Salt of halogen-substituted heterocyclic compound
WO2017055313A1 (en)2015-10-012017-04-06Bayer Pharma AktiengesellschaftAmido-substituted azole compounds
WO2017055316A1 (en)2015-10-012017-04-06Bayer Pharma AktiengesellschaftAmido-substituted azole compounds
AR108838A1 (en)2016-06-212018-10-03Bristol Myers Squibb Co CARBAMOYLOXIMETHYL ACID TRIAZOL CYCLOHEXILO AS LPA ANTAGONISTS
WO2018078009A1 (en)2016-10-292018-05-03Bayer Pharma AktiengesellschaftAmido-substituted cyclohexane derivatives
WO2018078005A1 (en)2016-10-292018-05-03Bayer Pharma AktiengesellschaftAmido-substituted azaspiro derivatives as tankyrase inhibitors
WO2018087126A1 (en)2016-11-092018-05-17Bayer Pharma AktiengesellschaftAmido-substituted cyclohexane derivatives as inhibitors of tankyrase
CN107827829A (en)*2017-11-072018-03-23大连理工大学Preparation method of 5 amide groups, 1,4,5 trisubstituted 1,2,3 triazole in aqueous phase and Biomedia
CN107721984A (en)*2017-11-072018-02-23大连理工大学A kind of preparation method of trisubstituted 1,2,3 triazole of new 5 amide groups 1,4,5
CN112041316B (en)*2017-12-192024-11-22百时美施贵宝公司 Isoxazole O-linked carbamoylcyclohexyl acids as LPA antagonists
WO2019126089A1 (en)2017-12-192019-06-27Bristol-Myers Squibb CompanyCyclohexyl acid pyrazole azines as lpa antagonists
JP7202383B2 (en)2017-12-192023-01-11ブリストル－マイヤーズ スクイブ カンパニー Pyrazole O-bridged carbamoylcyclohexylates as LPA antagonists
EP3728210A1 (en)2017-12-192020-10-28Bristol-Myers Squibb CompanyIsoxazole n-linked carbamoyl cyclohexyl acids as lpa antagonists
EP3728216B1 (en)2017-12-192023-09-06Bristol-Myers Squibb CompanyPyrazole n-linked carbamoyl cyclohexyl acids as lpa antagonists
BR112020012177A2 (en)2017-12-192020-11-24Bristol-Myers Squibb Company triazole azoles of cyclohexylic acid as lpa antagonists
CN112055711B (en)2017-12-192024-07-23百时美施贵宝公司Cyclohexylic acid triazolazine as LPA antagonist
WO2019126103A1 (en)2017-12-192019-06-27Bristol-Myers Squibb CompanyCyclohexyl acid pyrazole azoles as lpa antagonists
EP3728209A1 (en)2017-12-192020-10-28Bristol-Myers Squibb CompanyCyclohexyl acid isoxazole azines as lpa antagonists
JP7256807B2 (en)*2017-12-192023-04-12ブリストル－マイヤーズ スクイブ カンパニー Cyclohexylate isoxazole azoles as LPA antagonists
ES2946657T3 (en)2018-09-182023-07-24Bristol Myers Squibb Co Cyclopentyl acids as LPA antagonists
CN113366000A (en)2018-09-182021-09-07百时美施贵宝公司Oxabicyclic acids as LPA antagonists
CN111434653A (en)2019-01-152020-07-21武汉朗来科技发展有限公司Triazole compound and preparation method and application thereof
CA3158743A1 (en)2019-11-152021-05-20Gilead Sciences, Inc.Triazole carbamate pyridyl sulfonamides as lpa receptor antagonists and uses thereof
WO2021247215A1 (en)2020-06-032021-12-09Gilead Sciences, Inc.Lpa receptor antagonists and uses thereof
TWI838626B (en)2020-06-032024-04-11美商基利科學股份有限公司Lpa receptor antagonists and uses thereof
JP7701473B2 (en)2021-05-112025-07-01ギリアード サイエンシーズ， インコーポレイテッド LPA receptor antagonists and their uses
JP7709612B2 (en)2021-12-082025-07-16ギリアード サイエンシーズ， インコーポレイテッド LPA receptor antagonists and their uses
CN115745848A (en)*2022-12-072023-03-07上海优合生物科技有限公司Processing and synthesizing process of aminoguanidine

Family Cites Families (6)

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Publication numberPriority datePublication dateAssigneeTitle
WO2011159550A2 (en)*2010-06-142011-12-22Amidra Pharmaceuticals, Inc.Lysophosphatidic acid receptor antagonist and uses thereof
WO2011159633A1 (en)*2010-06-152011-12-22Amira Pharmaceuticals, Inc.Inhalable formulations of lysophosphatdic acid receptor antagonists
PH12013501136A1 (en)*2010-12-072013-07-08Amira Pharmaceuticals IncLysophosphatidic acid receptor antagonists and uses thereof
WO2012138648A1 (en)*2011-04-062012-10-11Irm LlcCompositions and methods for modulating lpa receptors
JP2014525932A (en)*2011-08-152014-10-02インターミューン， インコーポレイテッド Lysophosphatide acid receptor antagonist
KR20150021057A (en)*2012-06-202015-02-27에프. 호프만-라 로슈 아게N-alkyltriazole compounds as lpar antagonists

Also Published As

Publication numberPublication date
UA110310C2 (en)2015-12-10
MA37762B1 (en)2018-04-30
BR112014030674A2 (en)2017-06-27
CA2869564A1 (en)2013-12-27
ZA201408167B (en)2015-12-23
IL236087A0 (en)2015-02-01
CL2014003241A1 (en)2015-03-20
WO2013189865A1 (en)2013-12-27
JP2015520203A (en)2015-07-16
HK1206339A1 (en)2016-01-08
CN104395299A (en)2015-03-04
SG11201407228PA (en)2014-12-30
AU2013279513A1 (en)2014-10-16
EP2864301A1 (en)2015-04-29
KR20150011389A (en)2015-01-30
US20150133512A1 (en)2015-05-14
MX2014014711A (en)2015-03-04
MA37762A1 (en)2017-07-31
EA201492281A1 (en)2015-04-30
CO7131357A2 (en)2014-12-01
PE20142305A1 (en)2015-01-16
PH12014502363A1 (en)2015-01-12

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