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IN2012DN01855A - - Google Patents

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Publication number
IN2012DN01855A
IN2012DN01855AIN1855DEN2012AIN2012DN01855AIN 2012DN01855 AIN2012DN01855 AIN 2012DN01855AIN 1855DEN2012 AIN1855DEN2012 AIN 1855DEN2012AIN 2012DN01855 AIN2012DN01855 AIN 2012DN01855A
Authority
IN
India
Prior art keywords
compounds
infections
esters
compositions
useful
Prior art date
Application number
Inventor
Aesop Cho
Lee S Chong
Michael O'neil Hanrahan Clarke
Edward Doerffler
Choung U Kim
Qi Liu
William J Watkins
Jennifer R Zhang
Original Assignee
Gilead Sciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gilead Sciences IncfiledCriticalGilead Sciences Inc
Publication of IN2012DN01855ApublicationCriticalpatent/IN2012DN01855A/en

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Abstract

Provided are compounds of Formula I: and pharmaceutically acceptable salts and esters thereof. The compounds, compositions, and methods provided are useful for the treatment of Flaviviridae virus infections, particularly hepatitis C infections.
IN1855DEN20122009-09-092010-09-07IN2012DN01855A (en)

Applications Claiming Priority (2)

Application NumberPriority DateFiling DateTitle
US24087409P2009-09-092009-09-09
PCT/US2010/047983WO2011031669A1 (en)2009-09-092010-09-07Inhibitors of flaviviridae viruses

Publications (1)

Publication NumberPublication Date
IN2012DN01855Atrue IN2012DN01855A (en)2015-08-21

Family

ID=43028061

Family Applications (1)

Application NumberTitlePriority DateFiling Date
IN1855DEN2012IN2012DN01855A (en)2009-09-092010-09-07

Country Status (14)

CountryLink
US (2)US8501714B2 (en)
EP (1)EP2507249B1 (en)
JP (1)JP5774008B2 (en)
KR (1)KR20120081123A (en)
CN (1)CN102498118A (en)
AU (1)AU2010292411B2 (en)
BR (1)BR112012005438A2 (en)
CA (1)CA2771124C (en)
ES (1)ES2559437T3 (en)
IN (1)IN2012DN01855A (en)
MX (1)MX2012002925A (en)
NZ (1)NZ598208A (en)
PT (1)PT2507249E (en)
WO (1)WO2011031669A1 (en)

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CN101330547A (en)*2007-06-202008-12-24朗迅科技公司Medium resource distributed in VoIP network for providing service
PE20120666A1 (en)*2009-07-212012-06-01Gilead Sciences Inc INHIBITORS OF FLAVIVIRIDAE VIRUSES
WO2011031669A1 (en)*2009-09-092011-03-17Gilead Sciences, Inc.Inhibitors of flaviviridae viruses
SG182475A1 (en)2010-01-152012-08-30Gilead Sciences IncInhibitors of flaviviridae viruses
ES2543105T3 (en)*2010-01-152015-08-14Gilead Sciences, Inc. Flaviviridae virus inhibitors
WO2012006060A1 (en)*2010-06-282012-01-12Vertex Pharmaceuticals IncorporatedCompounds and methods for the treatment or prevention of flavivirus infections
MX2013000906A (en)*2010-07-222013-02-27Novartis Ag2,3,5-trisubstituted thiophene compounds and uses thereof.
US20130203706A1 (en)*2011-06-282013-08-08Vertex Pharmaceuticals IncorporatedCompounds and methods for the treatment or prevention of flavivirus infections
EP2734515B1 (en)2011-07-132015-11-04Gilead Sciences, Inc.Thiophen-2-carboxylic acid derivatives useful as inhibitors of flaviviridae viruses
GB201116559D0 (en)2011-09-262011-11-09Univ Leuven KathNovel viral replication inhibitors
US8927741B2 (en)2012-08-172015-01-06Gilead Sciences, Inc.Synthesis of an antiviral compound
US8759544B2 (en)2012-08-172014-06-24Gilead Sciences, Inc.Synthesis of an antiviral compound
US8841340B2 (en)2012-08-172014-09-23Gilead Sciences, Inc.Solid forms of an antiviral compound
LT3236972T (en)2014-12-262021-11-10Emory University ANTIVIRAL N4-HYDROXICITIDINE DERIVATIVES
FR3046793B1 (en)*2016-01-142018-01-05Les Laboratoires Servier NOVEL PHOSPHINAN DERIVATIVES AND AZAPHOSPHINANES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
WO2017197046A1 (en)2016-05-102017-11-16C4 Therapeutics, Inc.C3-carbon linked glutarimide degronimers for target protein degradation
WO2017197055A1 (en)2016-05-102017-11-16C4 Therapeutics, Inc.Heterocyclic degronimers for target protein degradation
WO2017197051A1 (en)2016-05-102017-11-16C4 Therapeutics, Inc.Amine-linked c3-glutarimide degronimers for target protein degradation
ES2990061T3 (en)2016-05-102024-11-28C4 Therapeutics Inc Spirocyclic degronimers for the degradation of target proteins
CN110769822A (en)2017-06-202020-02-07C4医药公司N/O-linked degron and degron bodies for protein degradation
HRP20241620T1 (en)2017-12-072025-01-31Emory University N4-HYDROXYCYTIDINE AND DERIVATIVES AND ANTIVIRAL USE RELATED THERETO

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US20020002199A1 (en)1998-03-122002-01-03Lone JeppesenModulators of protein tyrosine phosphatases (ptpases)
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JP4544857B2 (en)2001-06-112010-09-15ヴァイロケム ファーマ インコーポレイテッド Compounds and methods for the treatment or prevention of FLAVIRIRUS infection
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ES2345438T3 (en)2002-12-102010-09-23Virochem Pharma Inc. COMPOUNDS AND METHODS FOR THE TREATMENT OR PREVENTION OF INFECTIONS BY FLAVIVIRUS.
WO2004052885A1 (en)*2002-12-102004-06-24Virochem Pharma Inc.Compounds and methods for the treatment or prevention of flavivirus infections
DE10359791A1 (en)2003-12-192005-07-21Bayer Healthcare Ag Substituted thiophenes
AR047894A1 (en)2004-02-252006-03-01Wyeth Corp THIOPHEN DERIVATIVES AS INHIBITORS OF PROTEIN THYROSINE PHOSPHATASE 1B (PTPASA 1B); METHODS FOR THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM AND THEIR USE IN THE TREATMENT OF DISEASES MEDIATED BY PTPASA 1B
AU2005228899A1 (en)2004-03-302005-10-13Novartis Vaccines And Diagnostics, Inc.Substituted thiophene derivatives as anti-cancer agents
DE102005028077A1 (en)2004-12-222006-07-13Aicuris Gmbh & Co. Kg Alkynyl-substituted thiophenes
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EA016071B1 (en)2005-05-132012-01-30Вирокем Фарма Инк.Compounds and methods for the treatment or prevention of flavivirus infections
BRPI0707870A2 (en)2006-02-152011-05-10Sanofi Aventis Amino Alcohol-Substituted Arylthienopyrimidinones, Process for Preparation and Use as Medicines
DK2104674T3 (en)2006-11-152013-07-15Vertex Pharmaceuticals Canada Inc THIOPHEN ANALOGS FOR TREATMENT OR PREVENTION OF FLAVIVIRUS INFECTIONS
WO2008059042A1 (en)2006-11-172008-05-22Smithkline Beecham Corporation2-carboxy thiophene derivatives as anti viral agents
BRPI0922364A2 (en)2008-12-032017-08-29Presidio Pharmaceuticals Inc COMPOUND, PHARMACEUTICAL COMPOSITION AND USE OF A COMPOUND
PE20120666A1 (en)2009-07-212012-06-01Gilead Sciences Inc INHIBITORS OF FLAVIVIRIDAE VIRUSES
WO2011031669A1 (en)*2009-09-092011-03-17Gilead Sciences, Inc.Inhibitors of flaviviridae viruses
WO2011068715A1 (en)2009-11-252011-06-09Vertex Pharmaceuticals Incorporated5-alkynyl-thiophene-2-carboxylic acid derivatives and their use for the treatment or prevention of flavivirus infections
ES2543105T3 (en)2010-01-152015-08-14Gilead Sciences, Inc. Flaviviridae virus inhibitors
SG182475A1 (en)2010-01-152012-08-30Gilead Sciences IncInhibitors of flaviviridae viruses
MX2012014918A (en)2010-06-282013-04-08Vertex PharmaCompounds and methods for the treatment or prevention of flavivirus infections.
EP2734515B1 (en)2011-07-132015-11-04Gilead Sciences, Inc.Thiophen-2-carboxylic acid derivatives useful as inhibitors of flaviviridae viruses

Also Published As

Publication numberPublication date
EP2507249A1 (en)2012-10-10
BR112012005438A2 (en)2018-03-20
US8501714B2 (en)2013-08-06
AU2010292411B2 (en)2015-04-09
US8765722B2 (en)2014-07-01
ES2559437T3 (en)2016-02-12
NZ598208A (en)2014-02-28
PT2507249E (en)2016-02-15
KR20120081123A (en)2012-07-18
AU2010292411A1 (en)2012-03-15
MX2012002925A (en)2012-08-03
WO2011031669A1 (en)2011-03-17
CN102498118A (en)2012-06-13
US20130302280A1 (en)2013-11-14
CA2771124C (en)2019-01-15
EP2507249B1 (en)2015-11-11
CA2771124A1 (en)2011-03-17
HK1170740A1 (en)2013-03-08
US20120156166A1 (en)2012-06-21
JP5774008B2 (en)2015-09-02
JP2013504576A (en)2013-02-07

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