| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IL8181884AIL81818A (en) | 1983-06-15 | 1984-06-13 | 13-epi-steroids and process for the preparation thereof |
| IL7720485AIL77204A (en) | 1984-06-13 | 1985-12-03 | 11beta-(4-dimethylamino-phenyl)-13alpha-alkylogonane derivatives,process for the preparation thereof and pharmaceutical compositions containing the same |
| IL81818AIL81818A0 (en) | 1983-06-15 | 1987-03-08 | 13-epi-steroids and process for the preparation thereof |
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE3321826ADE3321826A1 (en) | 1983-06-15 | 1983-06-15 | 13 alpha -Alkylgonanes, the preparation thereof and pharmaceutical products containing these |
| DE19843413036DE3413036A1 (en) | 1984-04-04 | 1984-04-04 | 13a-Alkylgonanes, the preparation thereof and pharmaceutical products containing these |
| Publication Number | Publication Date |
|---|---|
| IL72085A0 IL72085A0 (en) | 1984-10-31 |
| IL72085Atrue IL72085A (en) | 1987-09-16 |
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL72085AIL72085A (en) | 1983-06-15 | 1984-06-13 | 13alpha-alkylgonanes,processes for their preparation and pharmaceutical compositions containing them |
| Country | Link |
|---|---|
| EP (1) | EP0129499B1 (en) |
| JP (1) | JPH02167296A (en) |
| AU (1) | AU572849B2 (en) |
| CA (1) | CA1307784C (en) |
| DD (1) | DD218624A5 (en) |
| DE (1) | DE3468030D1 (en) |
| DK (1) | DK166729B1 (en) |
| ES (1) | ES8502612A1 (en) |
| FI (1) | FI78709C (en) |
| GR (1) | GR82210B (en) |
| HU (1) | HU191131B (en) |
| IE (1) | IE57620B1 (en) |
| IL (1) | IL72085A (en) |
| NO (1) | NO160521C (en) |
| NZ (1) | NZ208441A (en) |
| PT (1) | PT78732B (en) |
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3446661A1 (en)* | 1984-12-18 | 1986-06-19 | Schering AG, 1000 Berlin und 4709 Bergkamen | NEW 13 (ALPHA) -ALKYL-17 (BETA) - (3-ACYLOXYPROPYL) GONANA |
| DE3506785A1 (en)* | 1985-02-22 | 1986-08-28 | Schering AG, Berlin und Bergkamen, 1000 Berlin | 11SS-N, N-DIMETHYLAMINOPHENYL ESTRADIENE, THE PRODUCTION THEREOF AND PHARMACEUTICAL PREPARATIONS CONTAINING THEM |
| DE3630030A1 (en)* | 1986-09-01 | 1988-03-03 | Schering Ag | 13 (ALPHA) -ALKYLGONAN- (DELTA) (UP ARROW) 9 (UP ARROW) (UP ARROW) ((UP ARROW) (UP ARROW) 1 (UP ARROW) 1 (UP ARROW)) (UP ARROW) -5, 10-EPOXIDE |
| US4774236A (en)* | 1986-09-17 | 1988-09-27 | Research Triangle Institute | 17α-(substituted-methyl)-17β-hydroxy/esterified hydroxy steroids and pharmaceutical compositions containing them |
| IE60780B1 (en)* | 1987-01-23 | 1994-08-10 | Akzo Nv | New 11-aryl steroid derivatives |
| EP0310542B1 (en)* | 1987-10-01 | 1994-06-08 | Schering Aktiengesellschaft | Antigestagenic and antioestrogenic compounds for the treatment of hormone-dependent tumours |
| BE1004905A4 (en)* | 1987-12-30 | 1993-02-23 | Roussel Uclaf | NOVEL 17BETA-OH 19-NOR DERIVATIVES SUBSTITUTED IN 17ALPHA, THEIR PREPARATION PROCESS, THEIR APPLICATION AS MEDICAMENTS AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM. |
| US4954490A (en)* | 1988-06-23 | 1990-09-04 | Research Triangle Institute | 11 β-substituted progesterone analogs |
| DE3822770A1 (en)* | 1988-07-01 | 1990-01-04 | Schering Ag | 13-ALKYL-11SS-PHENYLGONANE |
| DE3832303A1 (en)* | 1988-09-20 | 1990-04-12 | Schering Ag | 11SS-PHENYL-14SSH STEROIDS |
| US5372996A (en)* | 1989-03-10 | 1994-12-13 | Endorecherche, Inc. | Method of treatment of androgen-related diseases |
| US5364847A (en)* | 1989-03-10 | 1994-11-15 | Endorecherche | Inhibitors of sex steroid biosynthesis and methods for their production and use |
| HUT60139A (en)* | 1989-07-07 | 1992-08-28 | Endorecherche Inc | Process for producing pharmaceutical composition suitable for treating prostate cancer connected with androgen |
| HUT60280A (en)* | 1989-07-07 | 1992-08-28 | Endorecherche Inc | Process for producing androgen derivatives inhibiting sexual steroidal activity, as well as pharmaceutical compositions comprising same |
| ATE172469T1 (en)* | 1989-08-04 | 1998-11-15 | Schering Ag | 11 BETA-ARYL-GONA-4,9-DIENE-3-ONE |
| FR2654337B1 (en)* | 1989-11-15 | 1994-08-05 | Roussel Uclaf | NOVEL BIODEGRADABLE INJECTABLE MICROSPHERES PREPARATION METHOD AND INJECTABLE SUSPENSIONS CONTAINING THEM. |
| DE4008584A1 (en)* | 1990-03-15 | 1991-09-26 | Schering Ag | METHOD FOR PRODUCING INTERMEDIATE PRODUCTS FOR THE ANTIGESTAGE SYNTHESIS (ONAPRISTONE SYNTHESIS) |
| US5407928A (en)* | 1990-08-15 | 1995-04-18 | Schering Aktiengesellschaft | 11β-aryl-gona-4,9-dien-3-ones |
| ES2103818T3 (en)* | 1990-08-18 | 1997-10-01 | Schering Ag | PROCEDURE FOR THE PREPARATION OF 17-OXO-STEROIDS. |
| US5472854A (en)* | 1990-08-18 | 1995-12-05 | Schering Aktiengesellschaft | Process for the production of 17-oxosteroids via the fermentative oxidation of 17β-hydroxysteroids by Mycobacterium |
| US7704983B1 (en) | 1992-03-02 | 2010-04-27 | Eastern Virginia Medical School | Antiprogestin method for reducing side effects associated with low dosage HRT and oral contraception |
| MX9301121A (en)* | 1992-03-02 | 1993-09-01 | Schering Ag | METHOD AND EQUIPMENT FOR ORAL CONTRACEPTION AND REGULATION OF MENSTRUATION WITH ESTROGEN / PROGESTIN / ANIPROGESTIN. |
| US5439913A (en) | 1992-05-12 | 1995-08-08 | Schering Aktiengesellschaft | Contraception method using competitive progesterone antagonists and novel compounds useful therein |
| JPH07506575A (en)* | 1992-05-21 | 1995-07-20 | アンドルシェルシュ・インコーポレイテッド | Inhibitor of testosterone 5α-reductase activity |
| DE4413185A1 (en)* | 1994-04-12 | 1995-10-19 | Schering Ag | 11beta, 19-bridged 13alpha alkyl steroids |
| DE4415590A1 (en)* | 1994-04-28 | 1995-11-02 | Schering Ag | Process for the stereoselective introduction of an alkynyl side chain to 11β-aryl-substituted 13alpha-alkylgonan-17-ones |
| DE4434488A1 (en) | 1994-09-14 | 1996-03-21 | Schering Ag | Steroid esters and amides, processes for their preparation and their pharmaceutical use |
| ZA9510926B (en) | 1994-12-23 | 1996-07-03 | Schering Ag | Compounds with progesterone-antagonistic and antiestrogenic action to be used together for female contraception |
| RU2129125C1 (en)* | 1995-04-06 | 1999-04-20 | Украинский научно-исследовательский институт фармакотерапии эндокринных заболеваний | METHOD OF SYNTHESIS OF 13α-TRIENE-19-NORANDROSTANE-3-OL-17-ONE AND ITS METHYL ESTER |
| EP0900234B1 (en) | 1996-05-01 | 2000-07-05 | THE GOVERNMENT OF THE UNITED STATES OF AMERICA as represented by the SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES | 21-substituted progesterone derivatives as new antiprogestational agents |
| US6900193B1 (en) | 1996-05-01 | 2005-05-31 | The United States Of America As Represented By The Department Of Health And Human Services | Structural modification of 19-norprogesterone I: 17-α-substituted-11-β-substituted-4-aryl and 21-substituted 19-norpregnadienedione as new antiprogestational agents |
| US6262042B1 (en)* | 1998-05-29 | 2001-07-17 | Research Triangle Institute | 17β-amino and hydroxylamino-11β-arylsteroids and their derivatives having agonist or antagonist hormonal properties |
| AU2015350241B2 (en) | 2014-11-17 | 2021-05-20 | Context Biopharma Inc. | Onapristone extended-release compositions and methods |
| BR112018005999A2 (en) | 2015-09-25 | 2019-01-08 | Context Biopharma Inc | methods for the production of onapristone intermediates |
| HK1255104A1 (en)* | 2015-12-15 | 2019-08-02 | Context Biopharma Inc. | Amorphous onapristone compositions and methods of making the same |
| WO2018102369A1 (en) | 2016-11-30 | 2018-06-07 | Arno Therapeutics, Inc. | Methods for onapristone synthesis dehydration and deprotection |
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2377418A1 (en)* | 1977-01-13 | 1978-08-11 | Roussel Uclaf | NEW 4,9-DIENIC 11B-SUBSTITUTE STEROID DERIVATIVES, THEIR PREPARATION PROCESS AND THEIR APPLICATION AS MEDICINAL PRODUCTS |
| ZA8231B (en)* | 1981-01-09 | 1982-11-24 | Roussel Uclaf | New 11 -substituted steroid derivatives, their preparation, their use as medicaments, the compositions containing them and the new intermediates thus obtained |
| DE3347126A1 (en)* | 1983-12-22 | 1985-07-11 | Schering AG, 1000 Berlin und 4709 Bergkamen | 11SS-ARYL-ESTRADIENE, THEIR PRODUCTION AND THE PHARMACEUTICAL PREPARATIONS CONTAINING THEM |
| CA1304916C (en)* | 1984-10-18 | 1992-07-14 | Wilhelm Bannwarth | Apparatus for the parallel performance of a plurality of chemical reaction sequences |
| Publication number | Publication date |
|---|---|
| IE57620B1 (en) | 1993-02-10 |
| DK288184A (en) | 1984-12-16 |
| GR82210B (en) | 1984-12-13 |
| CA1307784C (en) | 1992-09-22 |
| FI78709C (en) | 1989-09-11 |
| EP0129499A2 (en) | 1984-12-27 |
| PT78732B (en) | 1986-06-03 |
| JPH0369919B2 (en) | 1991-11-05 |
| NO160521B (en) | 1989-01-16 |
| EP0129499B1 (en) | 1987-12-09 |
| AU2936184A (en) | 1984-12-20 |
| IE841484L (en) | 1984-12-15 |
| AU572849B2 (en) | 1988-05-19 |
| DD218624A5 (en) | 1985-02-13 |
| NO160521C (en) | 1989-04-26 |
| HUT36139A (en) | 1985-08-28 |
| ES533260A0 (en) | 1985-02-01 |
| HU191131B (en) | 1987-01-28 |
| JPH02167296A (en) | 1990-06-27 |
| EP0129499A3 (en) | 1985-10-09 |
| NO842394L (en) | 1984-12-17 |
| DK166729B1 (en) | 1993-07-05 |
| ES8502612A1 (en) | 1985-02-01 |
| FI842395A7 (en) | 1984-12-16 |
| FI842395A0 (en) | 1984-06-13 |
| IL72085A0 (en) | 1984-10-31 |
| DK288184D0 (en) | 1984-06-12 |
| FI78709B (en) | 1989-05-31 |
| NZ208441A (en) | 1988-01-08 |
| PT78732A (en) | 1985-01-01 |
| DE3468030D1 (en) | 1988-01-21 |
| Publication | Publication Date | Title |
|---|---|---|
| IL72085A (en) | 13alpha-alkylgonanes,processes for their preparation and pharmaceutical compositions containing them | |
| DE3461090D1 (en) | 11-beta-aryl-estradienes, process for their preparation and pharmaceutical compositions containing them | |
| DE3263633D1 (en) | Imidazodiazepines, process for their preparation and pharmaceutical compositions containing them | |
| IL67826A0 (en) | Pyrazolooxazines,pyrazolothiazines and pyrazoloquinolines,their preparation and pharmaceutical compositions containing them | |
| IL71475A0 (en) | N-aryl-alpha-amino-carboxamides,their preparation and pharmaceutical compositions containing them | |
| IL73951A0 (en) | 2-phenyl-imidazoles,their preparation and pharmaceutical compositions containing them | |
| IL70756A (en) | 3-amino-pyridazine derivatives,their preparation and pharmaceutical compositions containing them | |
| EP0145121A3 (en) | Pyrazoloquinolines, process for their preparation, and pharmaceutical compositions containing them | |
| IL72151A0 (en) | Tetrahydropyridazinone derivatives,their preparation and pharmaceutical compositions containing them | |
| ZM9283A1 (en) | Substituted phenylsulfonyloxybenzimidazolecarbamates,processes for their preparation and pharmaceutical compositions containing the same | |
| IL71481A0 (en) | Substituted indeno-pyridazinones,their preparation and pharmaceutical compositions containing them | |
| IL68497A0 (en) | Benzoazacycloalkyl-spiro-imidazolidines,their preparation and pharmaceutical compositions containing them | |
| IL70755A (en) | 3-amino-4-cyano-pyridazine derivatives,their preparation and pharmaceutical compositions containing them | |
| IL68586A0 (en) | 4-aryl-4-piperidinecarbinols,their preparation and pharmaceutical compositions containing them | |
| IL71419A0 (en) | Phenylaminobenzenealkanols,their preparation and pharmaceutical compositions containing them | |
| IL68699A0 (en) | 3-phenoxy-1-azetidinecarboxamides,their preparation and pharmaceutical compositions containing them | |
| IL72123A0 (en) | Substituted phenylalkyl-piperazinyl-and homopiperazinyl-propyl-ureas and-thioureas,their preparation and pharmaceutical compositions containing them | |
| IL73471A (en) | N,n-di-n-propyl-4-hydroxy-3-methanesulfonamido-phenethylamine and pharmaceutical compositions containing them | |
| IL72307A0 (en) | Pyridinyl-2-pyrimidinamines,their preparation and pharmaceutical compositions containing them | |
| IL71110A0 (en) | Azolylmethylcycloalkanes,their preparation and pharmaceutical compositions containing them | |
| GB2138817B (en) | 4-pheny-tetrahydro-furano-pyridines, process for their preparation, and pharmaceutical compositions containing them | |
| IL72831A0 (en) | 2-aminomethyl-penem compounds,their preparation and pharmaceutical compositions containing them | |
| ZA841781B (en) | Penim compounds,methods for their preparation and pharmaceutical compositions containing them | |
| IL73075A0 (en) | Antihyperlipidemic n-benzoyl-sulfamates,n-benzylsulfamates and benzylsulfonamides,process for the preparation thereof and pharmaceutical compositions containing them | |
| IL69010A (en) | 15-alkoxyimino-14-oxoeburnamenines,their preparation and pharmaceutical compositions containing them |
| Date | Code | Title | Description |
|---|---|---|---|
| RH | Patent void |