| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US89859907P | 2007-01-31 | 2007-01-31 | |
| PCT/US2008/052439WO2008094989A2 (en) | 2007-01-31 | 2008-01-30 | Punctal plugs and methods of delivering therapeutic agents |
| Publication Number | Publication Date |
|---|---|
| HRP20120608T1true HRP20120608T1 (hr) | 2012-08-31 |
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HRP20120608ATHRP20120608T1 (hr) | 2007-01-31 | 2008-01-30 | Punktalni čepovi i postupci unosa terapijskih sredstava |
| Country | Link |
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| US (1) | US8753666B2 (es) |
| EP (1) | EP2114531B1 (es) |
| JP (1) | JP2010517630A (es) |
| KR (1) | KR20090104099A (es) |
| CN (1) | CN101600476B (es) |
| AR (1) | AR065235A1 (es) |
| AU (1) | AU2008210541B2 (es) |
| BR (1) | BRPI0807340A2 (es) |
| CA (1) | CA2674913A1 (es) |
| CL (1) | CL2008000306A1 (es) |
| CY (1) | CY1113075T1 (es) |
| DK (1) | DK2114531T3 (es) |
| ES (1) | ES2390991T3 (es) |
| HR (1) | HRP20120608T1 (es) |
| MX (1) | MX2009007394A (es) |
| PL (1) | PL2114531T3 (es) |
| PT (1) | PT2114531E (es) |
| RU (1) | RU2459646C2 (es) |
| SI (1) | SI2114531T1 (es) |
| TW (1) | TW200838485A (es) |
| UY (1) | UY30883A1 (es) |
| WO (1) | WO2008094989A2 (es) |
| ZA (1) | ZA200904713B (es) |
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050232972A1 (en) | 2004-04-15 | 2005-10-20 | Steven Odrich | Drug delivery via punctal plug |
| CN101052435B (zh) | 2004-07-02 | 2010-12-08 | Qlt塞子传递公司 | 治疗介质递送装置 |
| MX2008011714A (es) | 2006-03-14 | 2008-11-12 | Univ Southern California | Dispositivo de mems y metodo de administracion de agentes terapeuticos. |
| ES2640458T3 (es) | 2006-03-31 | 2017-11-03 | Mati Therapeutics Inc. | Implantes del sistema de drenaje nasolagrimal para terapia medicamentosa |
| JP5524841B2 (ja) | 2007-09-07 | 2014-06-18 | キュー エル ティー インク． | 涙管インプラント及び関連する方法 |
| ES2538838T3 (es) | 2007-09-07 | 2015-06-24 | Mati Therapeutics Inc. | Método para preparar insertos de fármacos para liberación sostenida de agentes terapéuticos |
| NZ583858A (en) | 2007-09-07 | 2012-08-31 | Quadra Logic Tech Inc | Lacrimal implant detection with detection device |
| EP2666510B1 (en) | 2007-12-20 | 2017-10-18 | University Of Southern California | Apparatus for controlled delivery of therapeutic agents |
| WO2009089094A2 (en) | 2008-01-03 | 2009-07-16 | University Of Southern California | Implantable drug-delivery devices, and apparatus and methods for refilling the devices |
| CN102105137B (zh)* | 2008-04-30 | 2015-01-07 | Qlt股份有限公司 | 复合泪管植入物及相关方法 |
| CN103394142B (zh) | 2008-05-08 | 2015-08-19 | 迷你泵有限责任公司 | 可植入药物传送装置与用于填充该装置的设备和方法 |
| US9623174B2 (en) | 2008-05-08 | 2017-04-18 | Minipumps, Llc | Implantable pumps and cannulas therefor |
| EP2323716B1 (en) | 2008-05-08 | 2015-03-04 | MiniPumps, LLC | Drug-delivery pumps |
| US9849238B2 (en) | 2008-05-08 | 2017-12-26 | Minipumps, Llc | Drug-delivery pump with intelligent control |
| CN105251007A (zh) | 2008-05-09 | 2016-01-20 | 马缇医疗股份有限公司 | 治疗青光眼和眼高血压的活性剂的持续释放递送 |
| US20090318549A1 (en)* | 2008-06-24 | 2009-12-24 | Qlt Plug Delivery, Inc. | Combination treatment of glaucoma |
| US20100104654A1 (en) | 2008-10-27 | 2010-04-29 | Allergan, Inc. | Prostaglandin and prostamide drug delivery systems and intraocular therapeutic uses thereof |
| CA2747556A1 (en)* | 2008-12-19 | 2010-06-24 | Qlt Inc. | Substance delivering punctum implants and methods |
| US20100209477A1 (en)* | 2009-01-23 | 2010-08-19 | Qlt Plug Delivery Inc. | Sustained release delivery of one or more agents |
| US8623395B2 (en) | 2010-01-29 | 2014-01-07 | Forsight Vision4, Inc. | Implantable therapeutic device |
| ES2747755T3 (es) | 2009-01-29 | 2020-03-11 | Forsight Vision4 Inc | Administración de un fármaco al segmento posterior |
| CN105997339B (zh)* | 2009-02-23 | 2018-09-04 | 马缇医疗股份有限公司 | 泪腺植入物 |
| US20100226962A1 (en)* | 2009-03-03 | 2010-09-09 | Rodstrom Theron R | Peri-corneal drug delivery device |
| US9421127B2 (en) | 2009-03-31 | 2016-08-23 | Johnson & Johnson Vision Care, Inc. | Punctal plugs |
| TWI495459B (zh)* | 2009-03-31 | 2015-08-11 | Johnson & Johnson Vision Care | 淚管塞（二） |
| US10206813B2 (en) | 2009-05-18 | 2019-02-19 | Dose Medical Corporation | Implants with controlled drug delivery features and methods of using same |
| US20120078362A1 (en) | 2009-05-18 | 2012-03-29 | Dose Medical Corporation | Drug eluting ocular implant |
| CN102596097B (zh) | 2009-06-03 | 2015-05-20 | 弗赛特实验室有限责任公司 | 一种眼插入件 |
| US8709467B2 (en) | 2009-06-26 | 2014-04-29 | Cute Lovable Teddy Bear, Llc. | Para-xylylene based microfilm elution devices |
| JP5758388B2 (ja) | 2009-08-18 | 2015-08-05 | ミニパンプス， エルエルシー | 適応制御を有する電解質薬物送達ポンプ |
| WO2011094170A1 (en) | 2010-01-27 | 2011-08-04 | Alcon Research, Ltd. | Pulsatile peri-corneal drug delivery device |
| WO2013022801A1 (en)* | 2011-08-05 | 2013-02-14 | Forsight Vision4, Inc. | Small molecule delivery with implantable therapeutic device |
| US9259352B2 (en) | 2010-03-29 | 2016-02-16 | Johnson & Johnson Vision Care, Inc. | Punctal plugs |
| US9259351B2 (en) | 2010-03-29 | 2016-02-16 | Johnson & Johnson Vision Care, Inc. | Punctal plugs |
| WO2011127064A2 (en)* | 2010-04-06 | 2011-10-13 | Allergan, Inc. | Sustained-release reservoir implants for intracameral drug delivery |
| ES2894940T3 (es) | 2010-08-05 | 2022-02-16 | Forsight Vision4 Inc | Aparato para tratar un ojo |
| PL2600930T3 (pl) | 2010-08-05 | 2021-09-06 | Forsight Vision4, Inc. | Urządzenie wstrzykujące do dostarczania leku |
| EP2600876B1 (en) | 2010-08-05 | 2015-04-29 | Forsight Vision4, Inc. | Combined drug delivery methods and apparatus |
| US8591484B2 (en) | 2010-09-15 | 2013-11-26 | AlphaMed, Inc. | Lacrimal punctum measurement and occlusion |
| EP2640360A2 (en) | 2010-11-19 | 2013-09-25 | Forsight Vision4, Inc. | Therapeutic agent formulations for implanted devices |
| US9603997B2 (en) | 2011-03-14 | 2017-03-28 | Minipumps, Llc | Implantable drug pumps and refill devices therefor |
| US10286146B2 (en) | 2011-03-14 | 2019-05-14 | Minipumps, Llc | Implantable drug pumps and refill devices therefor |
| US9919099B2 (en) | 2011-03-14 | 2018-03-20 | Minipumps, Llc | Implantable drug pumps and refill devices therefor |
| US20120276186A1 (en) | 2011-04-29 | 2012-11-01 | Ghebremeskel Alazar N | Sustained release latanoprost implant |
| US10398592B2 (en) | 2011-06-28 | 2019-09-03 | Forsight Vision4, Inc. | Diagnostic methods and apparatus |
| US20130018360A1 (en)* | 2011-07-13 | 2013-01-17 | Marissa Dockendorf | Method for delivering ophthalmic drugs |
| US9974685B2 (en) | 2011-08-29 | 2018-05-22 | Mati Therapeutics | Drug delivery system and methods of treating open angle glaucoma and ocular hypertension |
| US20130053794A1 (en) | 2011-08-29 | 2013-02-28 | Suzanne Cadden | Sustained release delivery of active agents to treat glaucoma and ocular hypertension |
| EP2755615B1 (en) | 2011-09-14 | 2022-04-06 | Forsight Vision5, Inc. | Ocular insert apparatus |
| PT2755600T (pt) | 2011-09-16 | 2021-04-19 | Forsight Vision4 Inc | Aparelhos de troca de fluidos |
| US8911227B2 (en)* | 2012-01-11 | 2014-12-16 | Johnson & Johnson Vision Care, Inc. | Device for injection molding silicone rubber |
| US10010448B2 (en) | 2012-02-03 | 2018-07-03 | Forsight Vision4, Inc. | Insertion and removal methods and apparatus for therapeutic devices |
| FR2986703B1 (fr)* | 2012-02-09 | 2015-01-16 | Horus Pharma | Dispositif de conditionnement et de distribution d'un produit a usage ophtalmique |
| JP6213560B2 (ja) | 2012-05-03 | 2017-10-18 | マティ セラピューティクス，インク． | 薬剤送達システムならびに開放隅角緑内障および高眼圧症を治療する方法 |
| RU2520834C2 (ru)* | 2012-09-11 | 2014-06-27 | Федеральное Государственное Бюджетное Образовательное Учреждение Высшего Профессионального Образования "Дагестанский Государственный Технический Университет" (Дгту) | Способ профилактики и лечения синдрома сухих глаз |
| HUE046128T2 (hu) | 2012-10-26 | 2020-02-28 | Forsight Vision5 Inc | Szemészeti rendszer gyógyszer szembe való késleltetett kibocsátására |
| WO2014113384A2 (en) | 2013-01-15 | 2014-07-24 | The Regents Of The University Of Colorado, A Body Corporate | Lacrimal system drug delivery device |
| EP2968113B8 (en) | 2013-03-14 | 2020-10-28 | Forsight Vision4, Inc. | Systems for sustained intraocular delivery of low solubility compounds from a port delivery system implant |
| WO2014160828A1 (en)* | 2013-03-27 | 2014-10-02 | Forsight Vision5, Inc. | Bimatoprost ocular silicone inserts and methods of use thereof |
| EP4302736A3 (en) | 2013-03-28 | 2024-04-03 | ForSight Vision4, Inc. | Ophthalmic implant for delivering therapeutic substances |
| CN105813578A (zh)* | 2013-10-15 | 2016-07-27 | 弗赛特影像5股份有限公司 | 用于增加或减少粘液的制剂和方法 |
| JP6655610B2 (ja) | 2014-05-29 | 2020-02-26 | グローコス コーポレーション | 制御された薬物送達機能を備えるインプラント及びそれを使用する方法 |
| RU2557423C1 (ru)* | 2014-06-25 | 2015-07-20 | Федеральное государственное бюджетное научное учреждение "Научно-исследовательский институт глазных болезней" (ФГБНУ "НИИ глазных болезней") | Способ лечения частичного дакриостеноза |
| RU2695563C2 (ru) | 2014-07-15 | 2019-07-24 | Форсайт Вижн4, Инк. | Способ и устройство для доставки глазного имплантата |
| CA2957548A1 (en) | 2014-08-08 | 2016-02-11 | Forsight Vision4, Inc. | Stable and soluble formulations of receptor tyrosine kinase inhibitors, and methods of preparation thereof |
| US10500091B2 (en) | 2014-11-10 | 2019-12-10 | Forsight Vision4, Inc. | Expandable drug delivery devices and methods of use |
| WO2016083891A1 (en) | 2014-11-25 | 2016-06-02 | Eyal Sheetrit | Compositions and methods for delivering a bio-active agent or bio-active agents |
| US20160296532A1 (en) | 2015-04-13 | 2016-10-13 | Forsight Vision5, Inc. | Ocular Insert Composition of a Semi-Crystalline or Crystalline Pharmaceutically Active Agent |
| CN106264777A (zh)* | 2015-06-08 | 2017-01-04 | 三鼎生物科技股份有限公司 | 辅助排泪管 |
| US11925578B2 (en) | 2015-09-02 | 2024-03-12 | Glaukos Corporation | Drug delivery implants with bi-directional delivery capacity |
| US10092387B2 (en)* | 2015-09-24 | 2018-10-09 | California Institute Of Technology | Implantable device for retaining live cells and providing nutrients thereto |
| WO2017053885A1 (en) | 2015-09-25 | 2017-03-30 | Glaukos Corporation | Punctal implants with controlled drug delivery features and methods of using same |
| AU2016355345A1 (en) | 2015-11-20 | 2018-05-31 | Forsight Vision4, Inc. | Porous structures for extended release drug delivery devices |
| US11857461B2 (en) | 2015-11-23 | 2024-01-02 | The Regents Of The University Of Colorado, A Body Corporate | Lacrimal system for drug delivery |
| CA3019822A1 (en) | 2016-04-05 | 2017-10-12 | Forsight Vision4, Inc. | Implantable ocular drug delivery devices |
| WO2017184881A1 (en) | 2016-04-20 | 2017-10-26 | Harold Alexander Heitzmann | Bioresorbable ocular drug delivery device |
| JP7054211B2 (ja) | 2016-05-20 | 2022-04-13 | ザ リージェンツ オブ ザ ユニバーシティ オブ コロラド，ア ボディー コーポレイト | 涙腺ドラッグ送給デバイス |
| CN106667656A (zh)* | 2016-06-30 | 2017-05-17 | 广州聚明生物科技有限公司 | 生物可降解泪道栓及其制备方法和应用 |
| CA3065474A1 (en)* | 2017-05-30 | 2018-12-06 | Eximore Ltd. | Compositions and methods for treating dry eye syndrome delivering antibiotic macrolide |
| BR112020010053A2 (pt) | 2017-11-21 | 2020-11-03 | Forsight Vision4, Inc. | aparelho para troca de fluido para sistema de liberação de porta expansível e métodos de uso do mesmo |
| AU2020207944A1 (en)* | 2019-01-18 | 2021-08-05 | Avisi Technologies, Inc. | Method and device for treating eye disease |
| KR102414314B1 (ko)* | 2019-02-27 | 2022-06-30 | 사회복지법인 삼성생명공익재단 | 코팅층을 포함하는 안질환용 임플란트 |
| CN111643269B (zh)* | 2020-05-14 | 2024-09-13 | 海思盖德(苏州)生物医学科技有限公司 | 一种植入体的多次植入装置及植入方法 |
| USD1033637S1 (en) | 2022-01-24 | 2024-07-02 | Forsight Vision4, Inc. | Fluid exchange device |
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3949750A (en) | 1974-10-07 | 1976-04-13 | Freeman Jerre M | Punctum plug and method for treating keratoconjunctivitis sicca (dry eye) and other ophthalmic aliments using same |
| US3992518A (en)* | 1974-10-24 | 1976-11-16 | G. D. Searle & Co. | Method for making a microsealed delivery device |
| US4053580A (en)* | 1975-01-01 | 1977-10-11 | G. D. Searle & Co. | Microsealed pharmaceutical delivery device |
| FR2534580A1 (fr)* | 1982-10-13 | 1984-04-20 | Synthelabo | Derives de phenyl-1 piperidino-2 propanol, leur preparation, et medicaments qui les contiennent |
| US5049142A (en)* | 1984-11-07 | 1991-09-17 | Herrick Robert S | Intracanalicular implant for horizontal canalicular blockade treatment of the eye |
| US5053030A (en)* | 1984-11-07 | 1991-10-01 | Herrick Robert S | Intracanalicular implant for horizontal canalicular blockade treatment of the eye |
| US4660546A (en)* | 1984-11-07 | 1987-04-28 | Robert S. Herrick | Method for treating for deficiency of tears |
| US5151444B1 (en) | 1987-09-18 | 1999-07-06 | R Tech Ueno Ltd | Ocular hypotensive agents |
| US4923699A (en)* | 1988-06-03 | 1990-05-08 | Kaufman Herbert E | Eye treatment suspension |
| US4915684A (en) | 1988-06-21 | 1990-04-10 | Mackeen Donald L | Method and apparatus for modulating the flow of lacrimal fluid through a punctum and associated canaliculus |
| ES2062102T5 (es) | 1988-09-06 | 2004-12-01 | Pharmacia Ab | Derivados de prostaglandinas para el tratamiento de glaucoma o hipertension ocular. |
| US5296504A (en) | 1988-09-06 | 1994-03-22 | Kabi Pharmacia | Prostaglandin derivatives for the treatment of glaucoma or ocular hypertension |
| SU1671295A1 (ru)* | 1988-10-24 | 1991-08-23 | Туркменский государственный медицинский институт | Устройство дл регулировани внутриглазного давлени при глаукоме |
| US4959048A (en) | 1989-01-17 | 1990-09-25 | Helix Medical, Inc. | Lacrimal duct occluder |
| US5067491A (en)* | 1989-12-08 | 1991-11-26 | Becton, Dickinson And Company | Barrier coating on blood contacting devices |
| US5163959A (en) | 1990-03-29 | 1992-11-17 | Herrick Robert S | Method for treating an eye with a canalicular implant having a collapsible flared section |
| US5171270A (en) | 1990-03-29 | 1992-12-15 | Herrick Robert S | Canalicular implant having a collapsible flared section and method |
| US5378475A (en) | 1991-02-21 | 1995-01-03 | University Of Kentucky Research Foundation | Sustained release drug delivery devices |
| US5283063A (en) | 1992-01-31 | 1994-02-01 | Eagle Vision | Punctum plug method and apparatus |
| ATE207360T1 (de) | 1992-03-19 | 2001-11-15 | R Tech Ueno Ltd | Behandlung von augenhochdruck mit betablockern und prostansäurederivaten |
| US5469867A (en) | 1992-09-02 | 1995-11-28 | Landec Corporation | Cast-in place thermoplastic channel occluder |
| US5352708A (en) | 1992-09-21 | 1994-10-04 | Allergan, Inc. | Non-acidic cyclopentane heptanoic acid, 2-cycloalkyl or arylalkyl derivatives as therapeutic agents |
| US5922773A (en) | 1992-12-04 | 1999-07-13 | The Children's Medical Center Corp. | Glaucoma treatment |
| US5417651A (en) | 1993-07-01 | 1995-05-23 | Guena; Nicolas | Punctum plug and monocanalicular probe for lacrimal pathology |
| US5510383A (en) | 1993-08-03 | 1996-04-23 | Alcon Laboratories, Inc. | Use of cloprostenol, fluprostenol and their salts and esters to treat glaucoma and ocular hypertension |
| AU7668894A (en) | 1993-08-13 | 1995-03-14 | Vitaphore Corporation | Hydrogel-based microsphere drug delivery systems |
| US5423777A (en) | 1993-10-27 | 1995-06-13 | Tajiri; Akira | Punctum plug |
| JP3486758B2 (ja) | 1994-06-24 | 2004-01-13 | 株式会社高研 | 注入可能な涙小管閉鎖剤 |
| US6149684A (en) | 1995-06-07 | 2000-11-21 | Herrick; Robert S. | Punctum plug having a thin elongated lip and a distal starting tip and method of using |
| US5723005A (en) | 1995-06-07 | 1998-03-03 | Herrick Family Limited Partnership | Punctum plug having a collapsible flared section and method |
| US5773019A (en) | 1995-09-27 | 1998-06-30 | The University Of Kentucky Research Foundation | Implantable controlled release device to deliver drugs directly to an internal portion of the body |
| US5741292A (en) | 1995-10-26 | 1998-04-21 | Eagle Vision | Punctum dilating and plug inserting instrument with push-button plug release |
| JP3792775B2 (ja) | 1996-04-08 | 2006-07-05 | 有限会社エム・エル・シー | 涙道挿管器具 |
| JPH1033584A (ja) | 1996-07-26 | 1998-02-10 | M L C:Kk | 涙道挿管器具 |
| US6041785A (en) | 1997-03-27 | 2000-03-28 | Eaglevision, Inc. | Punctum plug |
| US6016806A (en) | 1997-03-27 | 2000-01-25 | Eaglevision, Inc | Punctum plug |
| US6027470A (en) | 1998-06-10 | 2000-02-22 | Eagle Vision, Inc. | Punctum plug and method for inserting the same into the punctual opening |
| US5830171A (en) | 1997-08-12 | 1998-11-03 | Odyssey Medical, Inc. | Punctal occluder |
| NL1008090C2 (nl) | 1998-01-22 | 1999-07-26 | Lubberman Bernardus H M | Plug voor het afsluiten van een traanbuis. |
| US6290684B1 (en) | 1998-03-02 | 2001-09-18 | Herrick Family Limited Partnership | Punctum plug having a collapsible expanded section and distal tip extending substantially perpendicular thereto and method of inserting same |
| US6196993B1 (en)* | 1998-04-20 | 2001-03-06 | Eyelab Group, Llc | Ophthalmic insert and method for sustained release of medication to the eye |
| US6306114B1 (en) | 1998-06-16 | 2001-10-23 | Eagle Vision, Inc. | Valved canalicular plug for lacrimal duct occlusion |
| DE60020681T9 (de) | 1999-02-23 | 2006-08-31 | Angiotech International Ag | Zusammensetzungen und verfahren zur verbesserung der integrität von angegriffenen körperpassagewegen und höhlen |
| US6234175B1 (en) | 1999-03-23 | 2001-05-22 | Medennium, Inc. | Smart ocular plug design and method of insertion for punctal and intracanalicular implants |
| US6383192B1 (en) | 1999-04-28 | 2002-05-07 | Mlc Limited Company | Apparatus for intubation of lacrimal duct |
| US6344047B1 (en) | 2000-02-02 | 2002-02-05 | Eagle Vision | Instrument for inserting a punctum plug and method for manufacturing the instrument |
| AU2001234337A1 (en) | 2000-08-04 | 2002-02-18 | Medennium, Inc. | Ocular plug for punctal and intracanalicular implants |
| ATE359762T1 (de)* | 2001-01-09 | 2007-05-15 | Microchips Inc | Flexible mikrochip-vorrichtungen zur ophthalmologischen und anderen applikation |
| US6827738B2 (en)* | 2001-01-30 | 2004-12-07 | Timothy R. Willis | Refractive intraocular implant lens and method |
| US6685626B2 (en) | 2001-02-02 | 2004-02-03 | Regeneration Technologies, Inc. | Compositions, devices, methods, and kits for induction of adhesions |
| JP2002263124A (ja) | 2001-03-12 | 2002-09-17 | Masashige Nakayama | 動物の眼病治療方法及びそれに用いる人工涙管 |
| US6605108B2 (en)* | 2001-04-13 | 2003-08-12 | Eagle Vision, Inc. | Monocanalicular stent |
| US20040022853A1 (en) | 2001-04-26 | 2004-02-05 | Control Delivery Systems, Inc. | Polymer-based, sustained release drug delivery system |
| US7404825B2 (en) | 2001-06-11 | 2008-07-29 | Herrick Ii Robert S | Implant capable of forming a differential image in an eye |
| DE10133870A1 (de) | 2001-07-12 | 2003-02-06 | Chris P Lohmann | Ophthalmisches Mittel, Verwendung von EGF zur Behandlung von Dry Eye-Syndrom und Insert zur Verabreichung von EGF am Auge |
| US7204995B2 (en) | 2002-01-31 | 2007-04-17 | El-Sherif Dalia M | Treatment and control of dry eye by use of biodegradable polymer capsules |
| US20040043067A1 (en)* | 2002-06-19 | 2004-03-04 | Salamone Joseph C. | Fluorosiloxane matrix controlled diffusion drug delivery systems |
| PT1521573E (pt) | 2002-07-15 | 2008-02-08 | Alcon Inc | Composições de implantes farmacêuticos lipofílicos não poliméricos para utilização intra-ocular |
| FR2844182B1 (fr)* | 2002-09-11 | 2004-12-03 | Humanoptics Ag | Bouchon d'obturation d'un canalicule lacrymal |
| CA2497349C (en) | 2002-09-26 | 2008-07-08 | Angiotech International Ag | Perivascular wraps |
| CA2513884A1 (en) | 2003-01-24 | 2004-08-12 | Control Delivery Systems, Inc. | Controlled release of highly soluble agents |
| KR20050108345A (ko) | 2003-01-24 | 2005-11-16 | 컨트롤 딜리버리 시스템즈 인코포레이티드 | 탄산 탈수효소 저해제의 안구 전달을 위한 서방 장치와방법 |
| DE602004028638D1 (de)* | 2003-05-02 | 2010-09-23 | Surmodics Inc | System zur kontrollierten Freisetzung eines bioaktiven Wirkstoffs im hinteren Bereich des Auges |
| EP1682196A2 (en)* | 2003-11-10 | 2006-07-26 | Angiotech International Ag | Medical implants and anti-scarring agents |
| US20050232972A1 (en) | 2004-04-15 | 2005-10-20 | Steven Odrich | Drug delivery via punctal plug |
| US8722097B2 (en) | 2004-04-30 | 2014-05-13 | Allergan, Inc. | Oil-in-water method for making polymeric implants containing a hypotensive lipid |
| US7799336B2 (en)* | 2004-04-30 | 2010-09-21 | Allergan, Inc. | Hypotensive lipid-containing biodegradable intraocular implants and related methods |
| US7252006B2 (en)* | 2004-06-07 | 2007-08-07 | California Institute Of Technology | Implantable mechanical pressure sensor and method of manufacturing the same |
| CN101052435B (zh)* | 2004-07-02 | 2010-12-08 | Qlt塞子传递公司 | 治疗介质递送装置 |
| US7117870B2 (en) | 2004-07-26 | 2006-10-10 | Clarity Corporation | Lacrimal insert having reservoir with controlled release of medication and method of manufacturing the same |
| US7575781B2 (en)* | 2004-08-03 | 2009-08-18 | Sur Modics, Inc. | Method for depositing a polymeric coating on a substrate |
| US20080038317A1 (en)* | 2004-09-10 | 2008-02-14 | Chin-Ming Chang | Therapeutic Lacrimal Canalicular Inserts And Related Methods |
| ES2640458T3 (es) | 2006-03-31 | 2017-11-03 | Mati Therapeutics Inc. | Implantes del sistema de drenaje nasolagrimal para terapia medicamentosa |
| US9173773B2 (en) | 2006-06-21 | 2015-11-03 | Johnson & Johnson Vision Care, Inc. | Punctal plugs for the delivery of active agents |
| US9474645B2 (en) | 2006-06-21 | 2016-10-25 | Johnson & Johnson Vision Care, Inc. | Punctal plugs for the delivery of active agents |
| US20080045911A1 (en) | 2006-06-21 | 2008-02-21 | Borgia Maureen J | Punctal plugs for the delivery of active agents |
| US20080086101A1 (en) | 2006-08-25 | 2008-04-10 | David Freilich | Ophthalmic insert |
| Publication number | Publication date |
|---|---|
| TW200838485A (en) | 2008-10-01 |
| WO2008094989A2 (en) | 2008-08-07 |
| EP2114531B1 (en) | 2012-07-11 |
| AU2008210541A1 (en) | 2008-08-07 |
| CA2674913A1 (en) | 2008-08-07 |
| EP2114531A2 (en) | 2009-11-11 |
| RU2009132493A (ru) | 2011-03-10 |
| CY1113075T1 (el) | 2016-04-13 |
| JP2010517630A (ja) | 2010-05-27 |
| US20080181930A1 (en) | 2008-07-31 |
| KR20090104099A (ko) | 2009-10-05 |
| CN101600476A (zh) | 2009-12-09 |
| HK1133218A1 (en) | 2010-03-19 |
| US8753666B2 (en) | 2014-06-17 |
| RU2459646C2 (ru) | 2012-08-27 |
| ES2390991T3 (es) | 2012-11-20 |
| PT2114531E (pt) | 2012-10-09 |
| AR065235A1 (es) | 2009-05-27 |
| CN101600476B (zh) | 2013-08-21 |
| AU2008210541B2 (en) | 2013-09-26 |
| DK2114531T3 (da) | 2012-07-30 |
| MX2009007394A (es) | 2009-08-12 |
| UY30883A1 (es) | 2008-05-31 |
| BRPI0807340A2 (pt) | 2017-05-02 |
| CL2008000306A1 (es) | 2008-09-05 |
| WO2008094989A3 (en) | 2009-04-30 |
| ZA200904713B (en) | 2010-09-29 |
| PL2114531T3 (pl) | 2012-10-31 |
| SI2114531T1 (sl) | 2012-09-28 |
| Publication | Publication Date | Title |
|---|---|---|
| HRP20120608T1 (hr) | Punktalni čepovi i postupci unosa terapijskih sredstava | |
| US10632012B2 (en) | Sustained release delivery of active agents to treat glaucoma and ocular hypertension | |
| US20170172916A1 (en) | Punctal plug with active agent | |
| US20050250788A1 (en) | Aqueous outflow enhancement with vasodilated aqueous cavity | |
| JP2009540944A (ja) | 活性剤送達用の涙点プラグ | |
| JP2009540951A (ja) | 活性剤送達用の涙点プラグ | |
| TW200950817A (en) | Sustained release delivery of active agents to treat glaucoma and ocular hypertension | |
| TW201313255A (zh) | 遞送眼藥的方法 | |
| US20140025022A1 (en) | Drug delivery system and methods of treating open angle glaucoma and ocular hypertension | |
| WO2022251710A2 (en) | Intraocular devices, systems, and methods | |
| WO2017181835A1 (zh) | 一种慢性高眼压动物模型的建立方法 | |
| CN110037854B (zh) | 一种青光眼房水引流装置 | |
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| CN205434661U (zh) | 一种泪道引流器 | |
| Kaplowitz et al. | Minimally invasive glaucoma surgery: trabeculectomy ab interno | |
| CN202821800U (zh) | 施莱姆氏小管手术用导管 | |
| JP2015520628A5 (es) | ||
| Pate | Glaucoma and cannabinoids | |
| Meier-Gibbons et al. | Aqueous humor dynamics and its influence on glaucoma | |
| CN218187084U (zh) | 一种角膜给药装置 | |
| CN202437455U (zh) | 啄木鸟式泪道扩张引流管 | |
| RU2375997C1 (ru) | Способ герметизации глазного яблока при витреоретинальных вмешательствах | |
| Au et al. | Consensus statements A. trabeculectomy |