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GR1006917B - Angiotensin ii receptor antagonists based on histamin with sympathetic suppressant properties ans synthetic methods in the treatment of hypertension and cardiovascular diseases - Google Patents

Angiotensin ii receptor antagonists based on histamin with sympathetic suppressant properties ans synthetic methods in the treatment of hypertension and cardiovascular diseases

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Publication number
GR1006917B
GR1006917BGR20070100650AGR20070100650AGR1006917BGR 1006917 BGR1006917 BGR 1006917BGR 20070100650 AGR20070100650 AGR 20070100650AGR 20070100650 AGR20070100650 AGR 20070100650AGR 1006917 BGR1006917 BGR 1006917B
Authority
GR
Greece
Prior art keywords
angiotensin
receptor antagonists
cardiovascular diseases
hypertension
histamin
Prior art date
Application number
GR20070100650A
Other languages
Greek (el)
Other versions
GR20070100650A (en
Inventor
Μιχαηλ Μαραγκουδακις
Ιωαννης Ματσουκας
Δημητριος Βλαχακος
Χαραλαμπος Γαβρας
Original Assignee
Ελληνικα Φαρμακα Ερευνα Και Αναπτυξη Eldrug Α.Ε.,
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ελληνικα Φαρμακα Ερευνα Και Αναπτυξη Eldrug Α.Ε.,filedCriticalΕλληνικα Φαρμακα Ερευνα Και Αναπτυξη Eldrug Α.Ε.,
Priority to GR20070100650ApriorityCriticalpatent/GR1006917B/en
Priority to EP08826802Aprioritypatent/EP2188279A2/en
Priority to PCT/IB2008/002796prioritypatent/WO2009016514A2/en
Priority to US12/671,242prioritypatent/US20100216854A1/en
Publication of GR20070100650ApublicationCriticalpatent/GR20070100650A/en
Publication of GR1006917BpublicationCriticalpatent/GR1006917B/en

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Abstract

The present invention provides novel 1, 5 and 1, 3, 5-substituted imidazole compounds in hydrophilic or lipophilic form, which are useful as angiotensin II ATI receptor antagonists. The invention also provides pharmaceutical compositions containing such compounds, processes and intermediates for preparing compounds and their use in methods of treating hypertension and cardiovascular diseases.
GR20070100650A2007-08-012007-10-24Angiotensin ii receptor antagonists based on histamin with sympathetic suppressant properties ans synthetic methods in the treatment of hypertension and cardiovascular diseasesGR1006917B (en)

Priority Applications (4)

Application NumberPriority DateFiling DateTitle
GR20070100650AGR1006917B (en)2007-10-242007-10-24Angiotensin ii receptor antagonists based on histamin with sympathetic suppressant properties ans synthetic methods in the treatment of hypertension and cardiovascular diseases
EP08826802AEP2188279A2 (en)2007-08-012008-07-251,3 and 1,3,5 substituted imidazoles as antihypertensiva
PCT/IB2008/002796WO2009016514A2 (en)2007-08-012008-07-251, 3 and 1, 3, 5 substituted imidazoles as antihypertensiva
US12/671,242US20100216854A1 (en)2007-08-012008-07-251,3 and 1,3,5 substituted imidazoles as antihypertensives

Applications Claiming Priority (1)

Application NumberPriority DateFiling DateTitle
GR20070100650AGR1006917B (en)2007-10-242007-10-24Angiotensin ii receptor antagonists based on histamin with sympathetic suppressant properties ans synthetic methods in the treatment of hypertension and cardiovascular diseases

Publications (2)

Publication NumberPublication Date
GR20070100650A GR20070100650A (en)2009-05-15
GR1006917Btrue GR1006917B (en)2010-07-30

Family

ID=40248058

Family Applications (1)

Application NumberTitlePriority DateFiling Date
GR20070100650AGR1006917B (en)2007-08-012007-10-24Angiotensin ii receptor antagonists based on histamin with sympathetic suppressant properties ans synthetic methods in the treatment of hypertension and cardiovascular diseases

Country Status (1)

CountryLink
GR (1)GR1006917B (en)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication numberPriority datePublication dateAssigneeTitle
CA2028925A1 (en)*1989-11-061991-05-07Gerald R. GirardSubstituted n-(imidazolyl)alkyl alanine derivatives
FR2689508B1 (en)*1992-04-011994-06-17Fournier Ind & Sante IMIDAZOLE DERIVATIVES, THEIR PREPARATION PROCESS AND THEIR THERAPEUTIC APPLICATION.

Also Published As

Publication numberPublication date
GR20070100650A (en)2009-05-15

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PGPatent granted
MLLapse due to non-payment of fees

Effective date:20110503


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