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GB8308235D0 - Polypeptides - Google Patents

Polypeptides

Info

Publication number
GB8308235D0
GB8308235D0GB838308235AGB8308235AGB8308235D0GB 8308235 D0GB8308235 D0GB 8308235D0GB 838308235 AGB838308235 AGB 838308235AGB 8308235 AGB8308235 AGB 8308235AGB 8308235 D0GB8308235 D0GB 8308235D0
Authority
GB
United Kingdom
Prior art keywords
host cell
transformed
processes
recombinant dna
cells
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
GB838308235A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Celltech R&D Ltd
Original Assignee
Celltech Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filedlitigationCriticalhttps://patents.darts-ip.com/?family=10540204&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=GB8308235(D0)"Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Celltech LtdfiledCriticalCelltech Ltd
Priority to GB838308235ApriorityCriticalpatent/GB8308235D0/en
Publication of GB8308235D0publicationCriticalpatent/GB8308235D0/en
Priority to US06/672,265prioritypatent/US4816397A/en
Priority to DE3486179Tprioritypatent/DE3486179T3/en
Priority to EP92202982Aprioritypatent/EP0526953A1/en
Priority to AT84301996Tprioritypatent/ATE91716T1/en
Priority to PCT/GB1984/000094prioritypatent/WO1984003712A2/en
Priority to GB08407571Aprioritypatent/GB2137631B/en
Priority to EP84301996Aprioritypatent/EP0120694B2/en
Priority to JP59501609Aprioritypatent/JP2594900B2/en
Priority to JP22833294Aprioritypatent/JP3186463B2/en
Priority to JP9104862Aprioritypatent/JPH1080296A/en
Priority to JP2001063448Aprioritypatent/JP2001286291A/en
Pendinglegal-statusCriticalCurrent

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Abstract

This invention relates to multichain polypeptides or proteins and processes for their production in cells of host organisms which have been transformed by recombinant DNA techniques. According to a first aspect of the present invention, there is provided a process for producing a heterologous multichain polypeptide or protein in a single host cell, which comprises transforming the host cell with DNA sequences coding for each of the polypeptide chains and expressing said polypeptide chains in said transformed host cell. According to another aspect of the present invention there is provided as a product of recombinant DNA technology an Ig heavy or light chain or fragment thereof having an intact variable domain. The invention also provides a process for increasing the level of protein expression in a transformed host cell and vectors and transformed host cells for use in the processes. <IMAGE>
GB838308235A1983-03-251983-03-25PolypeptidesPendingGB8308235D0 (en)

Priority Applications (12)

Application NumberPriority DateFiling DateTitle
GB838308235AGB8308235D0 (en)1983-03-251983-03-25Polypeptides
JP59501609AJP2594900B2 (en)1983-03-251984-03-23 Multithiein polypeptides or proteins and methods for their production
EP84301996AEP0120694B2 (en)1983-03-251984-03-23Processes for the production of lg molecules
PCT/GB1984/000094WO1984003712A2 (en)1983-03-251984-03-23Multichain polypeptides or proteins and processes for their production
DE3486179TDE3486179T3 (en)1983-03-251984-03-23 Process for the preparation of immunoglobulins
EP92202982AEP0526953A1 (en)1983-03-251984-03-23Multichain polypeptides or proteins and processes for their production
AT84301996TATE91716T1 (en)1983-03-251984-03-23 PROCESSES FOR PRODUCTION OF POLYCHAIN POLYPEPTIDES OR PROTEINS.
US06/672,265US4816397A (en)1983-03-251984-03-23Multichain polypeptides or proteins and processes for their production
GB08407571AGB2137631B (en)1983-03-251984-03-23Multichain polypeptides and processes for their production
JP22833294AJP3186463B2 (en)1983-03-251994-09-22 Multi-chain polypeptide or protein
JP9104862AJPH1080296A (en)1983-03-251997-04-22Multichain polypeptide or protein
JP2001063448AJP2001286291A (en)1983-03-252001-03-07 Multi-chain polypeptide or protein

Applications Claiming Priority (1)

Application NumberPriority DateFiling DateTitle
GB838308235AGB8308235D0 (en)1983-03-251983-03-25Polypeptides

Publications (1)

Publication NumberPublication Date
GB8308235D0true GB8308235D0 (en)1983-05-05

Family

ID=10540204

Family Applications (2)

Application NumberTitlePriority DateFiling Date
GB838308235APendingGB8308235D0 (en)1983-03-251983-03-25Polypeptides
GB08407571AExpiredGB2137631B (en)1983-03-251984-03-23Multichain polypeptides and processes for their production

Family Applications After (1)

Application NumberTitlePriority DateFiling Date
GB08407571AExpiredGB2137631B (en)1983-03-251984-03-23Multichain polypeptides and processes for their production

Country Status (7)

CountryLink
US (1)US4816397A (en)
EP (2)EP0526953A1 (en)
JP (4)JP2594900B2 (en)
AT (1)ATE91716T1 (en)
DE (1)DE3486179T3 (en)
GB (2)GB8308235D0 (en)
WO (1)WO1984003712A2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication numberPriority datePublication dateAssigneeTitle
US7923221B1 (en)1983-04-082011-04-12Genentech, IncMethods of making antibody heavy and light chains having specificity for a desired antigen

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US4816397A (en)1989-03-28
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GB2137631B (en)1986-11-12
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ATE91716T1 (en)1993-08-15

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