| US7888121B2              (en) | 2003-08-08 | 2011-02-15 | Sangamo Biosciences, Inc. | Methods and compositions for targeted cleavage and recombination | 
| US20120196370A1              (en) | 2010-12-03 | 2012-08-02 | Fyodor Urnov | Methods and compositions for targeted genomic deletion | 
| DK2927318T3              (en) | 2003-08-08 | 2020-08-03 | Sangamo Therapeutics Inc | Method and compositions for targeted cleavage and recombination | 
| AU2006272634B2              (en) | 2005-07-26 | 2013-01-24 | Sangamo Therapeutics, Inc. | Targeted integration and expression of exogenous nucleic acid sequences | 
| JP5551432B2              (en) | 2006-05-25 | 2014-07-16 | サンガモ  バイオサイエンシーズ,  インコーポレイテッド | Methods and compositions for gene inactivation | 
| DK2049663T3              (en) | 2006-08-11 | 2015-06-01 | Dow Agrosciences Llc | ZINC FINGER NUCLEASE-MEDIATED HOMOLOGOUS RECOMBINATION | 
| EP2092068B1              (en) | 2006-12-14 | 2014-10-08 | Dow AgroSciences LLC | Optimized non-canonical zinc finger proteins | 
| DE602008003684D1              (en) | 2007-04-26 | 2011-01-05 | Sangamo Biosciences Inc | TARGETED INTEGRATION IN THE PPP1R12C POSITION | 
| EP2171052B1              (en) | 2007-07-12 | 2014-08-27 | Sangamo BioSciences, Inc. | Methods and compositions for inactivating alpha 1,6 fucosyltransferase (fut 8) gene expression | 
| US8563314B2              (en) | 2007-09-27 | 2013-10-22 | Sangamo Biosciences, Inc. | Methods and compositions for modulating PD1 | 
| SI2205749T1              (en) | 2007-09-27 | 2016-09-30 | Dow Agrosciences, Llc | Engineered zinc finger proteins targeting 5-enolpyruvyl shikimate-3-phosphate synthase genes | 
| US11235026B2              (en) | 2007-09-27 | 2022-02-01 | Sangamo Therapeutics, Inc. | Methods and compositions for modulating PD1 | 
| CA2700231C              (en) | 2007-09-27 | 2018-09-18 | Sangamo Biosciences, Inc. | Rapid in vivo identification of biologically active nucleases | 
| EP2597155B1              (en) | 2007-10-25 | 2016-11-23 | Sangamo BioSciences, Inc. | Methods and compositions for targeted integration | 
| JP2011518555A              (en) | 2008-04-14 | 2011-06-30 | サンガモ  バイオサイエンシーズ,  インコーポレイテッド | Linear donor constructs for targeted integration | 
| EP2274430B1              (en) | 2008-04-30 | 2016-09-14 | SanBio, Inc. | Neural regenerating cells with alterations in dna methylation | 
| JP2011521643A              (en) | 2008-05-28 | 2011-07-28 | サンガモ  バイオサイエンシーズ,  インコーポレイテッド | Composition for linking a DNA binding domain and a cleavage domain | 
| CA2893175C              (en) | 2008-06-10 | 2016-09-06 | Sangamo Biosciences, Inc. | Methods and compositions for generation of bax- and bak-deficient cell lines | 
| AU2009283194B2              (en) | 2008-08-22 | 2014-10-16 | Sangamo Therapeutics, Inc. | Methods and compositions for targeted single-stranded cleavage and targeted integration | 
| AU2009311697B2              (en) | 2008-10-29 | 2014-12-18 | Sangamo Therapeutics, Inc. | Methods and compositions for inactivating glutamine synthetase gene expression | 
| SG172760A1              (en) | 2008-12-04 | 2011-08-29 | Sangamo Biosciences Inc | Genome editing in rats using zinc-finger nucleases | 
| DK2370575T3              (en) | 2008-12-17 | 2018-02-05 | Dow Agrosciences Llc | TARGETED INTEGRATION IN THE ZP15 LOCUS | 
| CA2934285C              (en) | 2009-02-04 | 2018-11-27 | Sangamo Biosciences, Inc. | Methods and compositions for treating neuropathies | 
| EP2408921B1              (en) | 2009-03-20 | 2017-04-19 | Sangamo BioSciences, Inc. | Modification of cxcr4 using engineered zinc finger proteins | 
| JP6215533B2              (en) | 2009-04-09 | 2017-10-18 | サンガモ セラピューティクス, インコーポレイテッド | Targeted integration into stem cells | 
| US8772008B2              (en) | 2009-05-18 | 2014-07-08 | Sangamo Biosciences, Inc. | Methods and compositions for increasing nuclease activity | 
| JP5798116B2              (en) | 2009-06-30 | 2015-10-21 | サンガモ バイオサイエンシーズ, インコーポレイテッド | Rapid screening of biologically active nucleases and isolation of nuclease modified cells | 
| EP2451837B1              (en) | 2009-07-08 | 2015-03-25 | Cellular Dynamics International, Inc. | Modified ips cells having a mutant form of human immunodeficiency virus (hiv) cellular entry gene | 
| CA2769262C              (en) | 2009-07-28 | 2019-04-30 | Sangamo Biosciences, Inc. | Methods and compositions for treating trinucleotide repeat disorders | 
| EP3156504B1              (en) | 2009-08-11 | 2018-10-31 | Sangamo Therapeutics, Inc. | Organisms homozygous for targeted modification | 
| BR122019025207B1              (en) | 2009-10-22 | 2022-10-04 | Sangamo Biosciences, Inc. | NON-NATURALLY OCCURRING ZINC FINGER PROTEIN AND FUSION PROTEIN | 
| US8956828B2              (en) | 2009-11-10 | 2015-02-17 | Sangamo Biosciences, Inc. | Targeted disruption of T cell receptor genes using engineered zinc finger protein nucleases | 
| CN106086047B              (en) | 2010-01-22 | 2021-07-06 | 陶氏益农公司 | Targeted genome engineering | 
| JP2013518602A              (en) | 2010-02-09 | 2013-05-23 | サンガモ  バイオサイエンシーズ,  インコーポレイテッド | Targeted genome modification by partially single-stranded donor molecules | 
| CN102939377B              (en) | 2010-04-26 | 2016-06-08 | 桑格摩生物科学股份有限公司 | Genome editing of Rosa loci using zinc finger nucleases | 
| HRP20200254T1              (en) | 2010-05-03 | 2020-05-29 | Sangamo Therapeutics, Inc. | PREPARATIONS FOR CONNECTING ZINC FINGER MODULE | 
| EP2571512B1              (en) | 2010-05-17 | 2017-08-23 | Sangamo BioSciences, Inc. | Novel dna-binding proteins and uses thereof | 
| US8945868B2              (en) | 2010-07-21 | 2015-02-03 | Sangamo Biosciences, Inc. | Methods and compositions for modification of a HLA locus | 
| KR101971741B1              (en) | 2010-07-23 | 2019-08-14 | 시그마-알드리치 컴퍼니., 엘엘씨 | Genome editing using targeting endonucleases and single-stranded nucleic acids | 
| EP2622090B1              (en) | 2010-09-27 | 2019-06-19 | Sangamo Therapeutics, Inc. | Compositions for inhibiting viral entry into cells | 
| BR112013008881B1              (en) | 2010-10-12 | 2021-12-07 | The Children's Hospital Of Philadelphia | NON-NATURALLY OCCURRING PROTEIN, ZINC FINGER NUCLEASE, AND COMPOSITION | 
| WO2012092379A2              (en) | 2010-12-29 | 2012-07-05 | Sigma-Aldrich Co. Llc | Cells having disrupted expression of proteins involved in adme and toxicology processes | 
| WO2012094132A1              (en) | 2011-01-05 | 2012-07-12 | Sangamo Biosciences, Inc. | Methods and compositions for gene correction | 
| WO2012139045A1              (en) | 2011-04-08 | 2012-10-11 | Gilead Biologics, Inc. | Methods and compositions for normalization of tumor vasculature by inhibition of loxl2 | 
| KR20140045398A              (en) | 2011-06-30 | 2014-04-16 | 시그마-알드리치 컴퍼니., 엘엘씨 | Cells deficient in cmp-n-acetylneuraminic acid hydroxylase and/or glycoprotein alpha-1,3-galactosyltransferase | 
| WO2013016446A2              (en) | 2011-07-25 | 2013-01-31 | Sangamo Biosciences, Inc. | Methods and compositions for alteration of a cystic fibrosis transmembrane conductance regulator (cftr) gene | 
| KR102061557B1              (en) | 2011-09-21 | 2020-01-03 | 상가모 테라퓨틱스, 인코포레이티드 | Methods and compositions for refulation of transgene expression | 
| JP6188703B2              (en) | 2011-10-27 | 2017-08-30 | サンガモ セラピューティクス, インコーポレイテッド | Methods and compositions for modifying the HPRT locus | 
| US9458205B2              (en) | 2011-11-16 | 2016-10-04 | Sangamo Biosciences, Inc. | Modified DNA-binding proteins and uses thereof | 
| CN110438083A              (en) | 2012-01-11 | 2019-11-12 | 西格马-奥尔德里奇有限责任公司 | The generation of recombinant protein with simple sugar-type | 
| JP6023218B2              (en) | 2012-01-27 | 2016-11-09 | サンバイオ,インコーポレイティド | Methods and compositions for modulating angiogenesis and vascular development | 
| CN108285491B              (en) | 2012-02-29 | 2021-08-10 | 桑格摩生物科学股份有限公司 | Methods and compositions for treating huntington's disease | 
| MX344903B              (en) | 2012-05-02 | 2017-01-11 | Dow Agrosciences Llc | Targeted modification of malate dehydrogenase. | 
| EP2847338B1              (en) | 2012-05-07 | 2018-09-19 | Sangamo Therapeutics, Inc. | Methods and compositions for nuclease-mediated targeted integration of transgenes | 
| ES2813080T3              (en) | 2012-07-11 | 2021-03-22 | Sangamo Therapeutics Inc | Methods and compositions for the treatment of lysosomal storage diseases | 
| WO2014011901A2              (en) | 2012-07-11 | 2014-01-16 | Sangamo Biosciences, Inc. | Methods and compositions for delivery of biologics | 
| US10648001B2              (en) | 2012-07-11 | 2020-05-12 | Sangamo Therapeutics, Inc. | Method of treating mucopolysaccharidosis type I or II | 
| IN2015DN01480A              (en) | 2012-08-29 | 2015-07-03 | Sangamo Biosciences Inc |  | 
| UA119135C2              (en) | 2012-09-07 | 2019-05-10 | ДАУ АГРОСАЙЄНСІЗ ЕлЕлСі | Engineered transgene integration platform (etip) for gene targeting and trait stacking | 
| RU2665811C2              (en) | 2012-09-07 | 2018-09-04 | ДАУ АГРОСАЙЕНСИЗ ЭлЭлСи | Fad3 performance loci and corresponding target site specific binding proteins capable of inducing targeted breaks | 
| JP6401704B2              (en) | 2012-10-10 | 2018-10-10 | サンガモ セラピューティクス, インコーポレイテッド | Compounds that modify T cells and uses thereof | 
| JP2016500254A              (en) | 2012-12-05 | 2016-01-12 | サンガモ バイオサイエンシーズ, インコーポレイテッド | Methods and compositions for the regulation of metabolic diseases | 
| CA2895117A1              (en) | 2012-12-13 | 2014-06-19 | James W. Bing | Precision gene targeting to a particular locus in maize | 
| WO2014125668A1              (en) | 2013-02-14 | 2014-08-21 | 国立大学法人大阪大学 | Method for isolating specific genomic region using molecule binding specifically to endogenous dna sequence | 
| JP6491113B2              (en) | 2013-02-25 | 2019-03-27 | サンガモ セラピューティクス, インコーポレイテッド | Methods and compositions for enhancing nuclease-mediated gene disruption | 
| CN105208866B              (en) | 2013-03-21 | 2018-11-23 | 桑格摩生物治疗股份有限公司 | Targeted disruption of the T cell receptor gene using engineered zinc finger protein nucleases | 
| AU2014248208C1              (en) | 2013-04-05 | 2023-04-27 | Corteva Agriscience Llc | Methods and compositions for integration of an exogenous sequence within the genome of plants | 
| WO2014182700A1              (en) | 2013-05-10 | 2014-11-13 | Sangamo Biosciences, Inc. | Delivery methods and compositions for nuclease-mediated genome engineering | 
| CA2910489A1              (en) | 2013-05-15 | 2014-11-20 | Sangamo Biosciences, Inc. | Methods and compositions for treatment of a genetic condition | 
| WO2015031619A1              (en) | 2013-08-28 | 2015-03-05 | Sangamo Biosciences, Inc. | Compositions for linking dna-binding domains and cleavage domains | 
| EP3058072B1              (en) | 2013-10-17 | 2021-05-19 | Sangamo Therapeutics, Inc. | Delivery methods and compositions for nuclease-mediated genome engineering | 
| EP3057432B1              (en) | 2013-10-17 | 2018-11-21 | Sangamo Therapeutics, Inc. | Delivery methods and compositions for nuclease-mediated genome engineering in hematopoietic stem cells | 
| JP6634022B2              (en) | 2013-11-04 | 2020-01-22 | ダウ アグロサイエンシィズ エルエルシー | Optimal soybean loci | 
| MX360318B              (en) | 2013-11-04 | 2018-10-29 | Dow Agrosciences Llc | Optimal maize loci. | 
| AU2014341929B2              (en) | 2013-11-04 | 2017-11-30 | Corteva Agriscience Llc | Optimal maize loci | 
| CA2926536C              (en) | 2013-11-04 | 2024-01-30 | Dow Agrosciences Llc | Optimal soybean loci for targeted transgene integration | 
| JP2016537341A              (en) | 2013-11-11 | 2016-12-01 | サンガモ バイオサイエンシーズ, インコーポレイテッド | Methods and compositions for treating Huntington's disease | 
| DK3068881T3              (en) | 2013-11-13 | 2019-04-15 | Childrens Medical Center | NUCLEASE-MEDIATED REGULATION OF GENEPRESSION | 
| WO2015089046A1              (en) | 2013-12-09 | 2015-06-18 | Sangamo Biosciences, Inc. | Methods and compositions for treating hemophilia | 
| EP3102673B1              (en) | 2014-02-03 | 2020-04-15 | Sangamo Therapeutics, Inc. | Methods and compositions for treatment of a beta thalessemia | 
| AU2015218576B2              (en) | 2014-02-24 | 2020-02-27 | Sangamo Therapeutics, Inc. | Methods and compositions for nuclease-mediated targeted integration | 
| KR20220013460A              (en) | 2014-03-04 | 2022-02-04 | 시그마-알드리치 컴퍼니., 엘엘씨 | Viral resistant cells and uses thereof | 
| JP6594891B2              (en) | 2014-03-18 | 2019-10-23 | サンガモ  セラピューティクス,  インコーポレイテッド | Methods and compositions for modulating zinc finger protein expression | 
| WO2015164748A1              (en) | 2014-04-24 | 2015-10-29 | Sangamo Biosciences, Inc. | Engineered transcription activator like effector (tale) proteins | 
| US9574211B2              (en) | 2014-05-13 | 2017-02-21 | Sangamo Biosciences, Inc. | Methods and compositions for prevention or treatment of a disease | 
| WO2015188056A1              (en) | 2014-06-05 | 2015-12-10 | Sangamo Biosciences, Inc. | Methods and compositions for nuclease design | 
| US20170142942A1              (en) | 2014-07-14 | 2017-05-25 | Washington State University | Nanos knock-out that ablates germline cells | 
| US9757420B2              (en) | 2014-07-25 | 2017-09-12 | Sangamo Therapeutics, Inc. | Gene editing for HIV gene therapy | 
| US9816074B2              (en) | 2014-07-25 | 2017-11-14 | Sangamo Therapeutics, Inc. | Methods and compositions for modulating nuclease-mediated genome engineering in hematopoietic stem cells | 
| US9616090B2              (en) | 2014-07-30 | 2017-04-11 | Sangamo Biosciences, Inc. | Gene correction of SCID-related genes in hematopoietic stem and progenitor cells | 
| SI3194570T1              (en) | 2014-09-16 | 2022-01-31 | Sangamo Therapeutics, Inc. | Nuclease-mediated methods and compositions for genomic engineering and hematopoietic stem cell correction | 
| US10889834B2              (en) | 2014-12-15 | 2021-01-12 | Sangamo Therapeutics, Inc. | Methods and compositions for enhancing targeted transgene integration | 
| HK1246690A1              (en) | 2015-01-21 | 2018-09-14 | Sangamo Therapeutics, Inc. | Methods and compositions for identification of highly specific nucleases | 
| US20180094243A1              (en) | 2015-04-03 | 2018-04-05 | Dana-Farber Cancer Institute, Inc. | Composition and methods of genome editing of b-cells | 
| US10179918B2              (en) | 2015-05-07 | 2019-01-15 | Sangamo Therapeutics, Inc. | Methods and compositions for increasing transgene activity | 
| BR112017024115A2              (en) | 2015-05-12 | 2018-08-07 | Sangamo Therapeutics Inc | nuclease-mediated gene expression regulation | 
| US9957501B2              (en) | 2015-06-18 | 2018-05-01 | Sangamo Therapeutics, Inc. | Nuclease-mediated regulation of gene expression | 
| CA2991301A1              (en) | 2015-07-13 | 2017-01-19 | Sangamo Therapeutics, Inc. | Delivery methods and compositions for nuclease-mediated genome engineering | 
| EP4361279A3              (en) | 2015-08-06 | 2024-07-17 | The Curators of the University of Missouri | Pathogen-resistant animals having modified cd163 genes | 
| JP6976249B2              (en) | 2015-11-23 | 2021-12-08 | サンガモ セラピューティクス, インコーポレイテッド | Methods and compositions for engineering immunity | 
| WO2017106528A2              (en) | 2015-12-18 | 2017-06-22 | Sangamo Biosciences, Inc. | Targeted disruption of the t cell receptor | 
| EA201891212A1              (en) | 2015-12-18 | 2019-01-31 | Сангамо Терапьютикс, Инк. | ADDRESS DISORGANIZATION OF GKGS CELL RECEPTOR | 
| CN109152847A              (en) | 2016-01-15 | 2019-01-04 | 桑格摩生物治疗股份有限公司 | For treating the method and composition of neurological disease | 
| US10724020B2              (en) | 2016-02-02 | 2020-07-28 | Sangamo Therapeutics, Inc. | Compositions for linking DNA-binding domains and cleavage domains | 
| KR20230088522A              (en) | 2016-07-21 | 2023-06-19 | 맥스시티 인코포레이티드 | Methods and compositions for modifying genomic dna | 
| KR20240144493A              (en) | 2016-08-24 | 2024-10-02 | 상가모 테라퓨틱스, 인코포레이티드 | Engineered target specific nucleases | 
| CN110325635B              (en) | 2016-08-24 | 2023-12-26 | 桑格摩生物治疗股份有限公司 | Regulation of gene expression using engineered nucleases | 
| US10960085B2              (en) | 2016-09-07 | 2021-03-30 | Sangamo Therapeutics, Inc. | Modulation of liver genes | 
| AU2017347928A1              (en) | 2016-10-31 | 2019-05-09 | Sangamo Therapeutics, Inc. | Gene correction of scid-related genes in hematopoietic stem and progenitor cells | 
| ES2968892T3              (en) | 2016-12-08 | 2024-05-14 | Univ Case Western Reserve | Methods and compositions to increase the production of functional myelin | 
| US20190390241A1              (en) | 2017-01-24 | 2019-12-26 | Sigma-Aldrich Co. Llc | Viral resistant cells and culture systems | 
| AU2018256877B2              (en) | 2017-04-28 | 2022-06-02 | Acuitas Therapeutics, Inc. | Novel carbonyl lipids and lipid nanoparticle formulations for delivery of nucleic acids | 
| WO2018204469A2              (en) | 2017-05-03 | 2018-11-08 | Sangamo Therapeutics, Inc. | Methods and compositions for modification of a cystic fibrosis transmembrane conductance regulator (cftr) gene | 
| US11512287B2              (en) | 2017-06-16 | 2022-11-29 | Sangamo Therapeutics, Inc. | Targeted disruption of T cell and/or HLA receptors | 
| WO2019094725A2              (en) | 2017-11-09 | 2019-05-16 | Sangamo Therapeutics, Inc. | Genetic modification of cytokine inducible sh2-containing protein (cish) gene | 
| EP3740480B1              (en) | 2018-01-17 | 2024-03-06 | Vertex Pharmaceuticals Incorporated | Dna-pk inhibitors | 
| BR112020014140A2              (en) | 2018-01-17 | 2020-12-01 | Vertex Pharmaceuticals Incorporated | dna-pk inhibitors | 
| RU2020129448A              (en) | 2018-02-08 | 2022-03-09 | Сангамо Терапьютикс, Инк. | DESIGNED TARGET-SPECIFIC NUCLEASE | 
| JP7332622B2              (en) | 2018-04-18 | 2023-08-23 | サンガモ セラピューティクス, インコーポレイテッド | Zinc finger protein compositions for regulation of huntingtin (HTT) | 
| US11690921B2              (en) | 2018-05-18 | 2023-07-04 | Sangamo Therapeutics, Inc. | Delivery of target specific nucleases | 
| US12129485B2              (en) | 2018-05-23 | 2024-10-29 | National University Of Singapore | Blockade of CD2 surface expression and expression of chimeric antigen receptors for immunotherapy of T-cell malignancies | 
| EP3841204A4              (en) | 2018-08-23 | 2022-05-18 | Sangamo Therapeutics, Inc. | Engineered target specific base editors | 
| EP4234570A3              (en) | 2018-09-18 | 2023-12-13 | Sangamo Therapeutics, Inc. | Programmed cell death 1 (pd1) specific nucleases | 
| EP3852911B1              (en) | 2018-09-21 | 2025-01-22 | Acuitas Therapeutics, Inc. | Systems and methods for manufacturing lipid nanoparticles and liposomes | 
| HUE068416T2              (en) | 2019-01-11 | 2024-12-28 | Acuitas Therapeutics Inc | Lipids for lipid nanoparticle delivery of active agents | 
| AU2019428629A1              (en) | 2019-02-06 | 2021-01-28 | Sangamo Therapeutics, Inc. | Method for the treatment of mucopolysaccharidosis type I | 
| BR112021019448A2              (en) | 2019-04-02 | 2021-11-30 | Sangamo Therapeutics Inc | Methods for treating beta-thalassemia | 
| US20230212613A1              (en) | 2020-05-06 | 2023-07-06 | Cellectis S.A. | Methods for targeted insertion of exogenous sequences in cellular genomes | 
| US20230279440A1              (en) | 2020-05-06 | 2023-09-07 | Cellectis S.A. | Methods to genetically modify cells for delivery of therapeutic proteins | 
| CN116096702A              (en) | 2020-07-16 | 2023-05-09 | 爱康泰生治疗公司 | Cationic Lipids for Lipid Nanoparticles | 
| US12152251B2              (en) | 2020-08-25 | 2024-11-26 | Kite Pharma, Inc. | T cells with improved functionality | 
| MX2023005665A              (en) | 2020-11-16 | 2023-08-01 | Pig Improvement Co Uk Ltd | Influenza a-resistant animals having edited anp32 genes. | 
| KR20240103014A              (en) | 2021-11-09 | 2024-07-03 | 암젠 인크 | Method for generating antibody peptide conjugates | 
| WO2023105244A1              (en) | 2021-12-10 | 2023-06-15 | Pig Improvement Company Uk Limited | Editing tmprss2/4 for disease resistance in livestock | 
| CN118647600A              (en) | 2021-12-16 | 2024-09-13 | 爱康泰生治疗公司 | Lipids for lipid nanoparticle formulation | 
| EP4486874A1              (en) | 2022-03-04 | 2025-01-08 | Sigma-Aldrich Co., LLC | Metabolic selection via the asparagine biosynthesis pathway | 
| WO2024013514A2              (en) | 2022-07-15 | 2024-01-18 | Pig Improvement Company Uk Limited | Gene edited livestock animals having coronavirus resistance | 
| KR20250078982A              (en) | 2022-09-30 | 2025-06-04 | 시그마-알드리치 컴퍼니., 엘엘씨 | Metabolic selection through the glycine-formate biosynthetic pathway | 
| CN120283057A              (en) | 2022-09-30 | 2025-07-08 | 西格马-奥尔德里奇有限责任公司 | Metabolic selection via serine biosynthetic pathway | 
| WO2024238723A1              (en) | 2023-05-16 | 2024-11-21 | Omega Therapeutics, Inc. | Methods and compositions for modulating pcsk9 expression | 
| WO2024238726A1              (en) | 2023-05-16 | 2024-11-21 | Omega Therapeutics, Inc. | Methods and compositions for modulating methylation of a target gene | 
| WO2025019742A1              (en) | 2023-07-19 | 2025-01-23 | Omega Therapeutics, Inc. | Methods and compositions for modulating ctnnb1 expression | 
| WO2025029740A1              (en) | 2023-07-31 | 2025-02-06 | Sigma-Aldrich Co. Llc | Metabolic selection via the alanine biosynthesis pathway | 
| WO2025194124A1              (en) | 2024-03-14 | 2025-09-18 | Tessera Therapeutics, Inc. | Modified st1cas9 guide nucleic acids |