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FR2358895A1 - EXCIPIENT FOR THERAPEUTIC COMPOSITIONS IN TABLETS - Google Patents

EXCIPIENT FOR THERAPEUTIC COMPOSITIONS IN TABLETS

Info

Publication number
FR2358895A1
FR2358895A1FR7709055AFR7709055AFR2358895A1FR 2358895 A1FR2358895 A1FR 2358895A1FR 7709055 AFR7709055 AFR 7709055AFR 7709055 AFR7709055 AFR 7709055AFR 2358895 A1FR2358895 A1FR 2358895A1
Authority
FR
France
Prior art keywords
excipient
tablets
therapeutic compositions
content
hydroxypropylmethytlcellulose
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7709055A
Other languages
French (fr)
Other versions
FR2358895B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by IndividualfiledCriticalIndividual
Publication of FR2358895A1publicationCriticalpatent/FR2358895A1/en
Application grantedgrantedCritical
Publication of FR2358895B1publicationCriticalpatent/FR2358895B1/fr
Grantedlegal-statusCriticalCurrent

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Abstract

Translated fromFrench

L'invention concerne un excipient pour composition thérapeutique en comprimés destinée à un traitement systémique prolongé. L'excipient se compose d'hydroxypropylméthylcellulose ou d'un mélange d'hydroxypropylméthytlcellulose et d'éthylcellulose en proportion pouvant aller jusqu'à 20 %, et il est obtenu en humidifiant ce produit de départ jusqu'à un taux d'humidité d'au moins 85 %, puis en le déshydratant jusqu'à un taux d'humidité compris entre 2 et 10 %, la substance traitée ayant une teneur en groupes carbonyle de 0,92 à 1,43 g/100 g et une teneur en groupes carboxyle de 0.54 à 0,57 g/100 g.The invention relates to an excipient for a therapeutic tablet composition for prolonged systemic treatment. The excipient consists of hydroxypropylmethylcellulose or a mixture of hydroxypropylmethytlcellulose and ethylcellulose in a proportion of up to 20%, and it is obtained by humidifying this starting material to a humidity of at least 85%, followed by drying to a moisture content of between 2 and 10%, the treated substance having a carbonyl content of 0.92-1.43 g / 100 g and a group content carboxyl from 0.54 to 0.57 g / 100 g.

FR7709055A1976-05-051977-03-25 EXCIPIENT FOR THERAPEUTIC COMPOSITIONS IN TABLETSGrantedFR2358895A1 (en)

Applications Claiming Priority (1)

Application NumberPriority DateFiling DateTitle
US68341076A1976-05-051976-05-05

Publications (2)

Publication NumberPublication Date
FR2358895A1true FR2358895A1 (en)1978-02-17
FR2358895B1 FR2358895B1 (en)1982-10-22

Family

ID=24743943

Family Applications (1)

Application NumberTitlePriority DateFiling Date
FR7709055AGrantedFR2358895A1 (en)1976-05-051977-03-25 EXCIPIENT FOR THERAPEUTIC COMPOSITIONS IN TABLETS

Country Status (10)

CountryLink
JP (1)JPS5817445B2 (en)
BR (1)BR7702882A (en)
CA (1)CA1103161A (en)
DE (1)DE2718260C2 (en)
FR (1)FR2358895A1 (en)
GB (1)GB1583801A (en)
IL (1)IL50175A0 (en)
MX (1)MX4545E (en)
SE (1)SE7704764L (en)
YU (1)YU43437B (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication numberPriority datePublication dateAssigneeTitle
GB2042888B (en)*1979-03-051983-09-28Teijin LtdPreparation for administration to the mucosa of the oral or nasal cavity
JPS6034925B2 (en)*1979-07-311985-08-12帝人株式会社 Long-acting nasal preparation and its manufacturing method
US4259314A (en)1979-12-101981-03-31Hans LoweyMethod and composition for the preparation of controlled long-acting pharmaceuticals
US4369172A (en)*1981-12-181983-01-18Forest Laboratories Inc.Prolonged release therapeutic compositions based on hydroxypropylmethylcellulose
JPS59501162A (en)*1982-06-241984-07-05キイ・フア−マシユ−テイカルズ・インコ−ポレイテツド Extended release propranolol tablets
JPS59193831A (en)*1983-04-181984-11-02Sankyo Co LtdPreparation of enteric drug
US4680323A (en)*1983-12-011987-07-14Hans LoweyMethod and composition for the preparation of controlled long-acting pharmaceuticals for oral administration
US4775535A (en)*1986-04-041988-10-04Hans LoweyMethod of preparing controlled long-acting pharmaceutical formulations in unit dosage form having uniform and comparable bioavailability characteristics
US4855143A (en)*1986-04-041989-08-08Hans LoweyMethod of preparing controlled long-acting pharmaceutical formulations in unit dosage form having uniform and comparable bioavailability characteristics
AU652723B2 (en)*1989-08-251994-09-08Bioglan Laboratories Ltd.Pharmaceutical compositions and a device for administering the same
JPH07112934A (en)*1993-10-151995-05-02Taiyo Yakuhin Kogyo KkSustained release preparation of pentoxyphylline and its production
US5948437A (en)*1996-05-231999-09-07Zeneca LimitedPharmaceutical compositions using thiazepine
US6099859A (en)1998-03-202000-08-08Andrx Pharmaceuticals, Inc.Controlled release oral tablet having a unitary core

Citations (4)

* Cited by examiner, † Cited by third party
Publication numberPriority datePublication dateAssigneeTitle
US3065143A (en)*1960-04-191962-11-20Richardson Merrell IncSustained release tablet
FR2179044A1 (en)*1972-04-031973-11-16Scherer Corp R P
AU452221B2 (en)*1971-09-201974-08-09Forest Laboratories, Inc.Long-acting oral carrier
US3965256A (en)*1972-05-161976-06-22SynergisticsSlow release pharmaceutical compositions

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication numberPriority datePublication dateAssigneeTitle
CA1018456A (en)*1972-06-261977-10-04Hans LoweyProlonged release lozenges

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication numberPriority datePublication dateAssigneeTitle
US3065143A (en)*1960-04-191962-11-20Richardson Merrell IncSustained release tablet
AU452221B2 (en)*1971-09-201974-08-09Forest Laboratories, Inc.Long-acting oral carrier
FR2179044A1 (en)*1972-04-031973-11-16Scherer Corp R P
US3965256A (en)*1972-05-161976-06-22SynergisticsSlow release pharmaceutical compositions

Also Published As

Publication numberPublication date
MX4545E (en)1982-06-10
BR7702882A (en)1978-01-31
DE2718260C2 (en)1983-08-11
JPS5817445B2 (en)1983-04-07
IL50175A0 (en)1976-09-30
YU184176A (en)1984-02-29
FR2358895B1 (en)1982-10-22
CA1103161A (en)1981-06-16
DE2718260A1 (en)1977-11-17
JPS52145514A (en)1977-12-03
SE7704764L (en)1977-11-06
YU43437B (en)1989-08-31
GB1583801A (en)1981-02-04

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