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ES481516A1 - A METHOD FOR PREPARING TEST MEDIA FOR ANALYZING THE UREA CONTENT OF FLUIDS. - Google Patents

A METHOD FOR PREPARING TEST MEDIA FOR ANALYZING THE UREA CONTENT OF FLUIDS.

Info

Publication number
ES481516A1
ES481516A1ES481516AES481516AES481516A1ES 481516 A1ES481516 A1ES 481516A1ES 481516 AES481516 AES 481516AES 481516 AES481516 AES 481516AES 481516 A1ES481516 A1ES 481516A1
Authority
ES
Spain
Prior art keywords
present
test
fluids
urea
determination
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES481516A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Corp
Original Assignee
Miles Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/039,113external-prioritypatent/US4215995A/en
Application filed by Miles Laboratories IncfiledCriticalMiles Laboratories Inc
Publication of ES481516A1publicationCriticalpatent/ES481516A1/en
Expiredlegal-statusCriticalCurrent

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Abstract

Translated fromSpanish

Un objeto de la presente invención es proporcionar medios de ensayo para la determinación del contenido de urea de los fluidos, en los que se consiga la estabilidad de los reactivos utilizados para la preparación de los medios de ensayo. Otro objeto de la presente invención es reducir a un mínimo las interferencia debidas a la turbidez del suero y a la presencia de bilirrubina, cuando se determina el contenido de urea del suero en sangre Todavía otro objeto de la presente invención es proporcionar medios den ensayo que tengan una especificidad y sensibilidad altas, para la determinación de urea en los fluidos, a lo largo de un margen de concentraciones. Aún otro objeto de la presente invención es proporcionar medios de ensayo colorimétricos, capaces de detectar urea, cuando la cantidad de fluido a someter a la determinación, es limitada. Un objeto adicional de la presente invención es proporcionar una determinación una determinación NUS, que pueda ser efectuada rápidamente, sin necesidad deun equipo altamente especializado De acuerdo con la presente invención, el medio de ensayo para detectar la ura presenta en un fluido de ensayo, comprende un miembro portador modificado con ácido, que incorpora reactivos separados entre si. Un reactivo es aldehido orto-ftálico, y el otro reactivos es 3- hidroxi-1,2,3,4-tetrahidrobenzo [h] quinoleina, 3-acetoxi-1,2,3,4- tetrahidrobenzo[h]quinoleína. o sus sales diclorhidrato. Ventajosamente, los reactivos están separados entre si, mediante un material polímero. El medio de ensayo puede ser utilizado mediante una inmersión momentánea del mismo en una muestra de ensayo, o introduciendo de otra manera la muestra de ensayo en la matriz portadora, y observando cualquier variación de color detectable que resulte.An object of the present invention is to provide test means for determining the urea content of fluids, in which the stability of the reagents used for the preparation of the test means is achieved. Another object of the present invention is to minimize interference due to serum turbidity and the presence of bilirubin, when determining the urea content of blood serum. Still another object of the present invention is to provide test media that have high specificity and sensitivity for the determination of urea in fluids, over a range of concentrations. Still another object of the present invention is to provide colorimetric test means, capable of detecting urea, when the amount of fluid to be subjected to the determination is limited. A further object of the present invention is to provide a NUS determination, which can be carried out quickly, without the need for highly specialized equipment. According to the present invention, the test means for detecting ura present in a test fluid, comprises an acid-modified carrier member, which incorporates reagents separated from each other. One reactant is ortho-phthalic aldehyde, and the other reactants is 3-hydroxy-1,2,3,4-tetrahydrobenzo[h]quinoline, 3-acetoxy-1,2,3,4-tetrahydrobenzo[h]quinoline. or its dihydrochloride salts. Advantageously, the reactants are separated from each other by a polymer material. The test medium may be used by momentarily immersing it in a test sample, or by otherwise introducing the test sample into the carrier matrix, and observing any detectable color variation that results.

ES481516A1978-06-151979-06-13 A METHOD FOR PREPARING TEST MEDIA FOR ANALYZING THE UREA CONTENT OF FLUIDS.ExpiredES481516A1 (en)

Applications Claiming Priority (2)

Application NumberPriority DateFiling DateTitle
US91558778A1978-06-151978-06-15
US06/039,113US4215995A (en)1979-05-151979-05-15Test means and assay for determining the urea content of fluids

Publications (1)

Publication NumberPublication Date
ES481516A1true ES481516A1 (en)1980-01-16

Family

ID=26715824

Family Applications (1)

Application NumberTitlePriority DateFiling Date
ES481516AExpiredES481516A1 (en)1978-06-151979-06-13 A METHOD FOR PREPARING TEST MEDIA FOR ANALYZING THE UREA CONTENT OF FLUIDS.

Country Status (9)

CountryLink
AU (1)AU521386B2 (en)
CA (1)CA1108514A (en)
DE (1)DE2922748C2 (en)
ES (1)ES481516A1 (en)
FR (1)FR2434393A1 (en)
GB (1)GB2023815B (en)
IT (1)IT1116892B (en)
NL (1)NL187995C (en)
SE (1)SE444085B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication numberPriority datePublication dateAssigneeTitle
IT1219848B (en)*1988-03-031990-05-24Miles Italiana COMPOUND INDICATORS, METHOD FOR THEIR PREPARATION AND USE IN A STEEL SYSTEM ASSAY SYSTEM
PT1982182E (en)*2006-01-192012-06-01Lattec I SA novel dry stick device construction and method for determining an analyte in a sample using said dry stick device
EP1982183B9 (en)*2006-01-192012-12-12Lattec I/SDry stick device and method for determining an analyte in a sample

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication numberPriority datePublication dateAssigneeTitle
BE635883A (en)*1962-08-06
US3449080A (en)*1964-10-291969-06-10Johnson & JohnsonDevice for determining sodium or chloride concentration in body fluids
US3723064A (en)*1971-07-261973-03-27L LiottaMethod and device for determining the concentration of a material in a liquid
US3901657A (en)*1974-04-291975-08-26Sun Scient IncDevice for testing solutions and body fluids
US3890099A (en)*1974-07-051975-06-17David H JungColorimetric assay for urea
DE2436598C2 (en)*1974-07-301983-04-07Boehringer Mannheim Gmbh, 6800 Mannheim Stable test strip for the detection of ingredients in liquids
US4074972A (en)*1976-11-101978-02-21American Monitor CorporationUrea assay

Also Published As

Publication numberPublication date
DE2922748A1 (en)1979-12-20
DE2922748C2 (en)1984-03-22
IT1116892B (en)1986-02-10
NL7904720A (en)1979-12-18
FR2434393A1 (en)1980-03-21
NL187995B (en)1991-10-01
FR2434393B1 (en)1984-03-16
SE444085B (en)1986-03-17
GB2023815A (en)1980-01-03
GB2023815B (en)1982-12-15
NL187995C (en)1992-03-02
IT7949382A0 (en)1979-06-12
AU521386B2 (en)1982-04-01
SE7905266L (en)1979-12-16
AU4786579A (en)1980-11-20
CA1108514A (en)1981-09-08

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Effective date:19960603


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