EP3310342A4 - INORGANIC PARTICLES WITH QUICK-LOAD PROLONGED RELEASE IN DRUG SUBSTANCE - Google Patents

INORGANIC PARTICLES WITH QUICK-LOAD PROLONGED RELEASE IN DRUG SUBSTANCE Download PDF

Info

Publication number: EP3310342A4
Authority: EP; European Patent Office
Prior art keywords: quick; inorganic particles; drug substance; prolonged release; load
Prior art date: 2015-06-16
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Pending

Application number

EP16812105.1A

Other languages

German (de)

French (fr)

Other versions

EP3310342A1 (en

Inventor

Sanjib Bhattacharyya

Paul Ducheyne

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

University of Pennsylvania Penn

Original Assignee

University of Pennsylvania Penn

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2015-06-16

Filing date

2016-05-13

Publication date

2019-03-06

2016-05-13Application filed by University of Pennsylvania PennfiledCriticalUniversity of Pennsylvania Penn

2018-04-25Publication of EP3310342A1publicationCriticalpatent/EP3310342A1/en

2019-03-06Publication of EP3310342A4publicationCriticalpatent/EP3310342A4/en

StatusPendinglegal-statusCriticalCurrent

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
- A61K9/5115—Inorganic compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6921—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere
- A61K47/6923—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere the form being an inorganic particle, e.g. ceramic particles, silica particles, ferrite or synsorb
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Bioinformatics & Cheminformatics (AREA)
Epidemiology (AREA)
Inorganic Chemistry (AREA)
Communicable Diseases (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Ceramic Engineering (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Oncology (AREA)
General Chemical & Material Sciences (AREA)
Physics & Mathematics (AREA)
Biomedical Technology (AREA)
Nanotechnology (AREA)
Optics & Photonics (AREA)
Dermatology (AREA)
Medicinal Preparation (AREA)

EP16812105.1A2015-06-162016-05-13 INORGANIC PARTICLES WITH QUICK-LOAD PROLONGED RELEASE IN DRUG SUBSTANCEPendingEP3310342A4 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US201562180345P	2015-06-16	2015-06-16
PCT/US2016/032408WO2016204896A1 (en)	2015-06-16	2016-05-13	Inorganic controlled release particles with fast drug loading

Publications (2)

Publication Number	Publication Date
EP3310342A1 EP3310342A1 (en)	2018-04-25
EP3310342A4true EP3310342A4 (en)	2019-03-06

Family

ID=57545871

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EP16812105.1APendingEP3310342A4 (en)	2015-06-16	2016-05-13	INORGANIC PARTICLES WITH QUICK-LOAD PROLONGED RELEASE IN DRUG SUBSTANCE

Country Status (3)

Country	Link
EP (1)	EP3310342A4 (en)
CA (1)	CA2989795C (en)
WO (1)	WO2016204896A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IT202000023665A1 (en)*	2020-10-07	2022-04-07	Brenta S R L	NANOPARTICLES SYSTEM FOR VEHICLE AND ADMINISTRATION OF ACTIVE INGREDIENTS AND RELATED PRODUCTION METHOD, AS WELL AS BIOFILM ERADICATION ACTIVITIES

Citations (4)

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US20040076681A1 (en)*	2002-10-21	2004-04-22	Dennis Donn M.	Nanoparticle delivery system
EP1741717A1 (en)*	2005-07-05	2007-01-10	Interuniversitair Microelektronica Centrum	Metal nanostructures and pharmaceutical compositions
WO2012149268A1 (en)*	2011-04-29	2012-11-01	Selecta Biociences, Inc.	Tolerogenic synthetic nanocarriers for allergy therapy
EP2259798B1 (en)*	2008-03-05	2013-12-11	Baxter International Inc.	Surface-modified particles and methods for targeted drug delivery

Family Cites Families (5)

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DE102005016873A1 (en)*	2005-04-12	2006-10-19	Magforce Nanotechnologies Ag	New nano-particle useful for production of composition to treatment and/or prophylaxis of proliferative illnesses, cancer and bacterial infections, where nano-particle is bonded therapeutic substance
FR2921661B1 (en)*	2007-10-01	2013-05-31	Centre Nat Rech Scient	INORGANIC ORGANIC HYBRID SOLID WITH MODIFIED SURFACE.
WO2011130114A1 (en)*	2010-04-12	2011-10-20	Iowa State University Research Foundation, Inc.	Nanoparticles and nanoparticle compositions
US11135174B2 (en)*	2011-04-13	2021-10-05	The Trustees Of The University Of Pennsylvania	Coated mesoporous nanoparticles
US9567265B2 (en)*	2012-11-30	2017-02-14	Iowa State University Research Foundation, Inc.	Catalysts and methods of using the same

2016
- 2016-05-13EPEP16812105.1Apatent/EP3310342A4/enactivePending
- 2016-05-13CACA2989795Apatent/CA2989795C/enactiveActive
- 2016-05-13WOPCT/US2016/032408patent/WO2016204896A1/ennot_activeCeased

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20040076681A1 (en)*	2002-10-21	2004-04-22	Dennis Donn M.	Nanoparticle delivery system
EP1741717A1 (en)*	2005-07-05	2007-01-10	Interuniversitair Microelektronica Centrum	Metal nanostructures and pharmaceutical compositions
EP2259798B1 (en)*	2008-03-05	2013-12-11	Baxter International Inc.	Surface-modified particles and methods for targeted drug delivery
WO2012149268A1 (en)*	2011-04-29	2012-11-01	Selecta Biociences, Inc.	Tolerogenic synthetic nanocarriers for allergy therapy

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
BR]NING C ET AL: "Aldehyde-functionalized ethoxysilanes as new enzyme immobilization reagents", JOURNAL OF THE CHEMICAL SOCIETY, CHEMICAL COMMUNICATIONS, 1995, pages 2323 - 2324, XP002965494, ISSN: 0022-4936, DOI: 10.1039/C39950002323*
GAO ZHENYUAN ET AL: "Aldehydepropyl-functionalized mesostructured cellular foams: Efficient supports for immobilization of penicillin G acylase", JOURNAL OF MOLECULAR CATALYSIS. B, ENZYMATIC, vol. 105, 21 April 2014 (2014-04-21), pages 111 - 117, XP029026137, ISSN: 1381-1177, DOI: 10.1016/J.MOLCATB.2014.04.006*
LATTERICH MARTIN ET AL: "Label-free detection of biomolecular interactions in real time with a nano-porous silicon-based detection method", PROTEOME SCIENCE, vol. 6, no. 1, 4 November 2008 (2008-11-04), pages 31, XP021043843, ISSN: 1477-5956, DOI: 10.1186/1477-5956-6-31*
See also references ofWO2016204896A1*
XUANJUN WU ET AL: "Cytosolic delivery of proteins mediated by aldehyde-displaying silica nanoparticles with pH-responsive characteristics", JOURNAL OF MATERIALS CHEMISTRY, vol. 22, no. 33, 2012, pages 17121, XP055543145, ISSN: 0959-9428, DOI: 10.1039/c2jm33434h*
YANG LING ET AL: "One-pot synthesis of aldehyde-functionalized mesoporous silica-Fe3O4nanocomposites for immobilization of penicillin G acylase", MICROPOROUS AND MESOPOROUS MATERIALS, vol. 197, 5 June 2014 (2014-06-05), pages 1 - 7, XP029015821, ISSN: 1387-1811, DOI: 10.1016/J.MICROMESO.2014.05.044*

Also Published As

Publication number	Publication date
CA2989795A1 (en)	2016-12-22
WO2016204896A1 (en)	2016-12-22
CA2989795C (en)	2023-12-12
EP3310342A1 (en)	2018-04-25

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Legal Events

Date	Code	Title	Description
2016-12-23	STAA	Information on the status of an ep patent application or granted ep patent	Free format text:STATUS: THE INTERNATIONAL PUBLICATION HAS BEEN MADE
2018-03-23	PUAI	Public reference made under article 153(3) epc to a published international application that has entered the european phase	Free format text:ORIGINAL CODE: 0009012
2018-03-23	STAA	Information on the status of an ep patent application or granted ep patent	Free format text:STATUS: REQUEST FOR EXAMINATION WAS MADE
2018-04-25	17P	Request for examination filed	Effective date:20180116
2018-04-25	AK	Designated contracting states	Kind code of ref document:A1 Designated state(s):AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
2018-04-25	AX	Request for extension of the european patent	Extension state:BA ME
2018-09-19	DAV	Request for validation of the european patent (deleted)
2018-09-19	DAX	Request for extension of the european patent (deleted)
2019-01-25	REG	Reference to a national code	Ref country code:DE Ref legal event code:R079 Free format text:PREVIOUS MAIN CLASS: A61K0009140000 Ipc:A61K0047690000
2019-03-06	A4	Supplementary search report drawn up and despatched	Effective date:20190131
2019-03-06	RIC1	Information provided on ipc code assigned before grant	Ipc:A61K 9/14 20060101ALI20190125BHEP Ipc:A61K 47/69 20170101AFI20190125BHEP Ipc:A61P 31/04 20060101ALI20190125BHEP Ipc:A61K 9/50 20060101ALI20190125BHEP
2022-08-26	STAA	Information on the status of an ep patent application or granted ep patent	Free format text:STATUS: EXAMINATION IS IN PROGRESS
2022-09-28	17Q	First examination report despatched	Effective date:20220825
2023-06-28	P01	Opt-out of the competence of the unified patent court (upc) registered	Effective date:20230523

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