EP1986685A4 - COMPOSITIONS OF VACCINE DELIVERY MODES AND METHODS OF USE - Google Patents

COMPOSITIONS OF VACCINE DELIVERY MODES AND METHODS OF USE

Info

Publication number: EP1986685A4
Authority: EP; European Patent Office
Prior art keywords: compositions; methods; vaccine delivery; delivery modes; modes
Prior art date: 2006-01-31
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Withdrawn

Other versions

Inventor

William Turnell

Kristin Defife

Maria A Vitiello

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Medivas LLC

Original Assignee

Medivas LLC

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2006-01-31

Filing date

2007-01-31

Publication date

2009-02-25

2006-01-31Priority claimed from PCT/US2006/003575external-prioritypatent/WO2006088647A1/en

2006-01-31Priority claimed from US11/345,021external-prioritypatent/US20060188469A1/en

2006-01-31Priority claimed from PCT/US2006/003412external-prioritypatent/WO2006083874A2/en

2006-01-31Priority claimed from US11/344,689external-prioritypatent/US20060177416A1/en

2006-02-01Priority claimed from US11/345,815external-prioritypatent/US20060188486A1/en

2006-12-07Priority claimed from US11/636,230external-prioritypatent/US20070160622A1/en

2007-01-31Application filed by Medivas LLCfiledCriticalMedivas LLC

2008-11-05Publication of EP1986685A2publicationCriticalpatent/EP1986685A2/en

2009-02-25Publication of EP1986685A4publicationCriticalpatent/EP1986685A4/en

StatusWithdrawnlegal-statusCriticalCurrent

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
- A61K39/001102—Receptors, cell surface antigens or cell surface determinants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
- A61K31/785—Polymers containing nitrogen
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/385—Haptens or antigens, bound to carriers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/10—Cellular immunotherapy characterised by the cell type used
- A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
- A61K40/41—Vertebrate antigens
- A61K40/42—Cancer antigens
- A61K40/4271—Melanoma antigens
- A61K40/4272—Melan-A/MART
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
- A61K40/41—Vertebrate antigens
- A61K40/42—Cancer antigens
- A61K40/4271—Melanoma antigens
- A61K40/4273—Glycoprotein 100 [Gp100]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
- A61K40/46—Viral antigens
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
- A61K47/593—Polyesters, e.g. PLGA or polylactide-co-glycolide
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
- A61K47/595—Polyamides, e.g. nylon
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55561—CpG containing adjuvants; Oligonucleotide containing adjuvants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6093—Synthetic polymers, e.g. polyethyleneglycol [PEG], Polymers or copolymers of (D) glutamate and (D) lysine

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Epidemiology (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Mycology (AREA)
Immunology (AREA)
Microbiology (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Oncology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Communicable Diseases (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Cell Biology (AREA)
Virology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Medicinal Preparation (AREA)
Peptides Or Proteins (AREA)

EP07762672A2006-01-312007-01-31 COMPOSITIONS OF VACCINE DELIVERY MODES AND METHODS OF USEWithdrawnEP1986685A4 (en)

Applications Claiming Priority (9)

Application Number	Priority Date	Filing Date	Title
PCT/US2006/003575WO2006088647A1 (en)	2005-02-17	2006-01-31	Polymer particle delivery compositions and methods of use
US11/345,021US20060188469A1 (en)	2003-10-14	2006-01-31	Vaccine delivery compositions and methods of use
PCT/US2006/003412WO2006083874A2 (en)	2005-02-01	2006-01-31	Vaccine delivery compositions and methods of use
US11/344,689US20060177416A1 (en)	2003-10-14	2006-01-31	Polymer particle delivery compositions and methods of use
US11/345,815US20060188486A1 (en)	2003-10-14	2006-02-01	Wound care polymer compositions and methods for use thereof
US84242306P	2006-09-05	2006-09-05
US85817306P	2006-11-10	2006-11-10
US11/636,230US20070160622A1 (en)	2005-12-07	2006-12-07	Method for assembling a polymer-biologic delivery composition
PCT/US2007/002704WO2007089870A2 (en)	2006-01-31	2007-01-31	Vaccine delivery compositions and methods of use

Publications (2)

Publication Number	Publication Date
EP1986685A2 EP1986685A2 (en)	2008-11-05
EP1986685A4true EP1986685A4 (en)	2009-02-25

Family

ID=56290916

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EP07762672AWithdrawnEP1986685A4 (en)	2006-01-31	2007-01-31	COMPOSITIONS OF VACCINE DELIVERY MODES AND METHODS OF USE

Country Status (4)

Country	Link
EP (1)	EP1986685A4 (en)
JP (1)	JP2009525341A (en)
CA (1)	CA2676601A1 (en)
WO (1)	WO2007089870A2 (en)

Families Citing this family (22)

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US20060177416A1 (en)	2003-10-14	2006-08-10	Medivas, Llc	Polymer particle delivery compositions and methods of use
WO2007038246A2 (en)	2005-09-22	2007-04-05	Medivas, Llc	Solid polymer delivery compositions and methods for use thereof
WO2007035938A2 (en)	2005-09-22	2007-03-29	Medivas, Llc	BIS-(α-AMINO)-DIOL-DIESTER-CONTAINING POLY(ESTER AMIDE) AND POLY(ESTER URETHANE) COMPOSITIONS AND METHODS OF USE
ATE534415T1 (en)	2005-12-13	2011-12-15	Harvard College	SCAFFOLDS FOR CELL TRANSPLANTATION
WO2009102465A2 (en)	2008-02-13	2009-08-20	President And Fellows Of Harvard College	Continuous cell programming devices
CN102686244A (en)*	2009-04-21	2012-09-19	西莱克塔生物科技公司	Immunonanotherapeutics providing a Th1-biased response
EP2435095A2 (en)*	2009-05-27	2012-04-04	Selecta Biosciences, Inc.	Immunomodulatory agent-polymeric compounds
BR112012029912A2 (en)	2010-05-26	2016-11-16	Selecta Biosciences Inc	Synthetic Nanotransport Combination Vaccines
US9408906B2 (en)	2010-06-04	2016-08-09	Flow Pharma, Inc.	Peptide particle formulation
PT2624873T (en)	2010-10-06	2020-03-04	Harvard College	Injectable, pore-forming hydrogels for materials-based cell therapies
US9873765B2 (en)	2011-06-23	2018-01-23	Dsm Ip Assets, B.V.	Biodegradable polyesteramide copolymers for drug delivery
US9963549B2 (en)	2011-06-23	2018-05-08	Dsm Ip Assets, B.V.	Biodegradable polyesteramide copolymers for drug delivery
JP2014521687A (en)	2011-07-29	2014-08-28	セレクタバイオサイエンシーズインコーポレーテッド	Synthetic nanocarriers that generate humoral and cytotoxic T lymphocyte (CTL) immune responses
CA2870309C (en)	2012-04-16	2024-02-20	President And Fellows Of Harvard College	Mesoporous silica compositions for modulating immune responses
EP3137105A4 (en)	2014-04-30	2017-12-27	President and Fellows of Harvard College	Combination vaccine devices and methods of killing cancer cells
AU2015366355B2 (en)	2014-12-18	2020-05-28	Dsm Ip Assets B.V.	Drug delivery system for delivery of acid sensitive drugs
CA3012602A1 (en)	2015-01-30	2016-08-04	President And Fellows Of Harvard College	Peritumoral and intratumoral materials for cancer therapy
EP3280464A4 (en)	2015-04-10	2018-09-26	President and Fellows of Harvard College	Immune cell trapping devices and methods for making and using the same
DE102015109996B3 (en)*	2015-06-22	2016-07-28	Gerresheimer Regensburg Gmbh	Device for opening capsules
JP7138864B2 (en)	2016-02-06	2022-09-20	プレジデントアンドフェローズオブハーバードカレッジ	Recapitulation of the hematopoietic niche to reconstitute immunity
MA45738A (en)	2016-07-13	2019-05-22	Harvard College	MIMETIC SCAFFOLDING OF ANTIGEN PRESENT CELLS AND METHODS FOR PREPARING AND USING THEM
WO2023032891A1 (en)*	2021-08-30	2023-03-09	東レ株式会社	Composition for enhancing immunogenicity

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WO2006083874A2 (en)*	2005-02-01	2006-08-10	Medivas, Llc.	Vaccine delivery compositions and methods of use
US20060188469A1 (en)*	2003-10-14	2006-08-24	Medivas, Llc	Vaccine delivery compositions and methods of use
WO2007067744A2 (en)*	2005-12-07	2007-06-14	Medivas, Llc	Method for assembling a polymer-biologic delivery composition

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2007
- 2007-01-31WOPCT/US2007/002704patent/WO2007089870A2/enactiveApplication Filing
- 2007-01-31EPEP07762672Apatent/EP1986685A4/ennot_activeWithdrawn
- 2007-01-31CACA002676601Apatent/CA2676601A1/ennot_activeAbandoned
- 2007-01-31JPJP2008553341Apatent/JP2009525341A/enactivePending

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WO2006083874A2 (en)*	2005-02-01	2006-08-10	Medivas, Llc.	Vaccine delivery compositions and methods of use
WO2007067744A2 (en)*	2005-12-07	2007-06-14	Medivas, Llc	Method for assembling a polymer-biologic delivery composition

Also Published As

Publication number	Publication date
CA2676601A1 (en)	2007-08-09
EP1986685A2 (en)	2008-11-05
JP2009525341A (en)	2009-07-09
WO2007089870A2 (en)	2007-08-09
WO2007089870A3 (en)	2008-05-02

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Legal Events

Date	Code	Title	Description
2008-10-03	PUAI	Public reference made under article 153(3) epc to a published international application that has entered the european phase	Free format text:ORIGINAL CODE: 0009012
2008-11-05	17P	Request for examination filed	Effective date:20080828
2008-11-05	AK	Designated contracting states	Kind code of ref document:A2 Designated state(s):AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR
2008-11-05	AX	Request for extension of the european patent	Extension state:AL BA HR MK RS
2009-02-25	A4	Supplementary search report drawn up and despatched	Effective date:20090123
2009-06-10	17Q	First examination report despatched	Effective date:20090512
2009-12-25	STAA	Information on the status of an ep patent application or granted ep patent	Free format text:STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN
2010-01-27	18D	Application deemed to be withdrawn	Effective date:20090801

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