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EP1929003A4 - Reagents for the detection of protein phosphorylation in carcinoma signaling pathways - Google Patents

Reagents for the detection of protein phosphorylation in carcinoma signaling pathways

Info

Publication number
EP1929003A4
EP1929003A4EP06814000AEP06814000AEP1929003A4EP 1929003 A4EP1929003 A4EP 1929003A4EP 06814000 AEP06814000 AEP 06814000AEP 06814000 AEP06814000 AEP 06814000AEP 1929003 A4EP1929003 A4EP 1929003A4
Authority
EP
European Patent Office
Prior art keywords
reagents
detection
signaling pathways
protein phosphorylation
carcinoma
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP06814000A
Other languages
German (de)
French (fr)
Other versions
EP1929003A2 (en
Inventor
Roberto Polakiewicz
Kimberly Lee
Charles Farnsworth
Ailan Guo
Klarisa Rikova
Yu Li
Albrecht Moritz
Erik Spek
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cell Signaling Technology Inc
Original Assignee
Cell Signaling Technology Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cell Signaling Technology IncfiledCriticalCell Signaling Technology Inc
Priority to EP10151010ApriorityCriticalpatent/EP2182057A1/en
Publication of EP1929003A2publicationCriticalpatent/EP1929003A2/en
Publication of EP1929003A4publicationCriticalpatent/EP1929003A4/en
Withdrawnlegal-statusCriticalCurrent

Links

Classifications

Landscapes

EP06814000A2005-08-312006-08-31Reagents for the detection of protein phosphorylation in carcinoma signaling pathwaysWithdrawnEP1929003A4 (en)

Priority Applications (1)

Application NumberPriority DateFiling DateTitle
EP10151010AEP2182057A1 (en)2005-08-312006-08-31Antibody agains phosphorylated Tyrosine for the detection of protein phosphorylation in carcinoma signaling pathways

Applications Claiming Priority (2)

Application NumberPriority DateFiling DateTitle
US71304105P2005-08-312005-08-31
PCT/US2006/033991WO2007027867A2 (en)2005-08-312006-08-31Reagents for the detection of protein phosphorylation in carcinoma signaling pathways

Publications (2)

Publication NumberPublication Date
EP1929003A2 EP1929003A2 (en)2008-06-11
EP1929003A4true EP1929003A4 (en)2009-04-29

Family

ID=37809500

Family Applications (2)

Application NumberTitlePriority DateFiling Date
EP06814000AWithdrawnEP1929003A4 (en)2005-08-312006-08-31Reagents for the detection of protein phosphorylation in carcinoma signaling pathways
EP10151010AWithdrawnEP2182057A1 (en)2005-08-312006-08-31Antibody agains phosphorylated Tyrosine for the detection of protein phosphorylation in carcinoma signaling pathways

Family Applications After (1)

Application NumberTitlePriority DateFiling Date
EP10151010AWithdrawnEP2182057A1 (en)2005-08-312006-08-31Antibody agains phosphorylated Tyrosine for the detection of protein phosphorylation in carcinoma signaling pathways

Country Status (2)

CountryLink
EP (2)EP1929003A4 (en)
WO (1)WO2007027867A2 (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication numberPriority datePublication dateAssigneeTitle
DE10254601A1 (en)2002-11-222004-06-03Ganymed Pharmaceuticals Ag Gene products differentially expressed in tumors and their use
DE102004024617A1 (en)2004-05-182005-12-29Ganymed Pharmaceuticals Ag Differentially expressed in tumors gene products and their use
EP1790664A1 (en)2005-11-242007-05-30Ganymed Pharmaceuticals AGMonoclonal antibodies against claudin-18 for treatment of cancer
WO2008030543A2 (en)*2006-09-082008-03-13Cell Signaling Technology, Inc.Tyrosine, serine and threonine phosphorylation sites
EP1983002A3 (en)*2007-04-192009-03-11Peter HornbeckTyrosine phosphorylation sites and antibodies specific for them
WO2010008838A2 (en)2008-06-232010-01-21Perkinelmer Health Sciences, Inc.Kinase substrates
WO2013052686A1 (en)2011-10-042013-04-11Expression Pathology, Inc.Srm/mrm assay for the receptor tyrosine-protein kinase erbb-4 protein (her4)
WO2013167153A1 (en)*2012-05-092013-11-14Ganymed Pharmaceuticals AgAntibodies useful in cancer diagnosis
WO2013174404A1 (en)2012-05-232013-11-28Ganymed Pharmaceuticals AgCombination therapy involving antibodies against claudin 18.2 for treatment of cancer
NZ707831A (en)2012-11-132018-11-30Astellas Pharma IncAgents for treatment of claudin expressing cancer diseases
WO2014127785A1 (en)2013-02-202014-08-28Ganymed Pharmaceuticals AgCombination therapy involving antibodies against claudin 18.2 for treatment of cancer
WO2014146672A1 (en)2013-03-182014-09-25Ganymed Pharmaceuticals AgTherapy involving antibodies against claudin 18.2 for treatment of cancer
WO2022103990A1 (en)*2020-11-122022-05-19Phosfish LlcMethods of modifying phosphorylated or sulfated tyrosine residues of polypeptides

Citations (1)

* Cited by examiner, † Cited by third party
Publication numberPriority datePublication dateAssigneeTitle
WO2007133702A2 (en)*2006-05-122007-11-22Cell Signaling Technology, Inc.Reagents for the detection of protein acetylation signaling pathways

Family Cites Families (11)

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Publication numberPriority datePublication dateAssigneeTitle
US4376110A (en)1980-08-041983-03-08Hybritech, IncorporatedImmunometric assays using monoclonal antibodies
US4474893A (en)1981-07-011984-10-02The University of Texas System Cancer CenterRecombinant monoclonal antibodies
US4659678A (en)1982-09-291987-04-21Serono Diagnostics LimitedImmunoassay of antigens
US4816567A (en)1983-04-081989-03-28Genentech, Inc.Recombinant immunoglobin preparations
US4727022A (en)1984-03-141988-02-23Syntex (U.S.A.) Inc.Methods for modulating ligand-receptor interactions and their application
US4676980A (en)1985-09-231987-06-30The United States Of America As Represented By The Secretary Of The Department Of Health And Human ServicesTarget specific cross-linked heteroantibodies
US5675063A (en)1995-02-281997-10-07Loyola University Of ChicagoImmortalized rabbit hybridoma fusion partner
US7198896B2 (en)1998-09-042007-04-03Cell Signaling Technology, Inc.Immunoaffinity isolation of modified peptides from complex mixtures
CA2457695A1 (en)2001-08-142003-02-27President And Fellows Of Harvard CollegeAbsolute quantification of proteins and modified forms thereof by multistage mass spectrometry
JP2003088388A (en)*2001-09-142003-03-25Herikkusu Kenkyusho:KkNEW FULL-LENGTH cDNA
WO2005035003A2 (en)*2003-09-222005-04-21Dihedron CorporationCompositions and methods for increasing drug efficiency

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication numberPriority datePublication dateAssigneeTitle
WO2007133702A2 (en)*2006-05-122007-11-22Cell Signaling Technology, Inc.Reagents for the detection of protein acetylation signaling pathways

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
ALBERTA J A ET AL: "Generation and utilization of phosphorylation state-specific antibodies to investigate signaling pathways.", CURRENT PROTOCOLS IN NEUROSCIENCE / EDITORIAL BOARD, JACQUELINE N. CRAWLEY ... [ET AL.] MAY 2001, vol. Chapter 3, May 2001 (2001-05-01), pages Unit 3.14, XP002518938, ISSN: 1934-8576*
MANDELL J W: "Phosphorylation state-specific antibodies: applications in investigative and diagnostic pathology", AMERICAN JOURNAL OF PATHOLOGY, AMERICAN SOCIETY FOR INVESTIGATIVE PATHOLOGY, US, vol. 163, no. 5, 1 November 2003 (2003-11-01), pages 1687 - 1698, XP003017035, ISSN: 0002-9440*
OGAWA R ET AL: "INCREASE OF PHOSPHOTYROSINE-CONTAINING PROTEINS IN HUMAN CARCINOMAS", JAPANESE JOURNAL OF CANCER RESEARCH, JAPANESE CANCER ASSOCIATION, TOKYO, JP, vol. 76, no. 11, 1 January 1985 (1985-01-01), pages 1049 - 1055, XP009113485, ISSN: 0910-5050*
PULFORD KAREN ET AL: "Immunohistochemical screening for oncogenic tyrosine kinase activation", JOURNAL OF PATHOLOGY, vol. 187, no. 5, April 1999 (1999-04-01), pages 588 - 593, XP002518937, ISSN: 0022-3417*

Also Published As

Publication numberPublication date
EP1929003A2 (en)2008-06-11
WO2007027867A3 (en)2007-12-21
EP2182057A1 (en)2010-05-05
WO2007027867A2 (en)2007-03-08

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Legal Events

DateCodeTitleDescription
PUAIPublic reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text:ORIGINAL CODE: 0009012

17PRequest for examination filed

Effective date:20080320

AKDesignated contracting states

Kind code of ref document:A2

Designated state(s):AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR

AXRequest for extension of the european patent

Extension state:AL BA HR MK RS

RIN1Information on inventor provided before grant (corrected)

Inventor name:SPEK, ERIK

Inventor name:MORITZ, ALBRECHT

Inventor name:LI, YU

Inventor name:RIKOVA, KLARISA

Inventor name:GUO, AILAN

Inventor name:FARNSWORTH, CHARLES

Inventor name:LEE, KIMBERLY

Inventor name:POLAKIEWICZ, ROBERTO

A4Supplementary search report drawn up and despatched

Effective date:20090330

17QFirst examination report despatched

Effective date:20090708

STAAInformation on the status of an ep patent application or granted ep patent

Free format text:STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18DApplication deemed to be withdrawn

Effective date:20100119


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