| Application Number | Priority Date | Filing Date | Title | 
|---|---|---|---|
| EP10151010AEP2182057A1 (en) | 2005-08-31 | 2006-08-31 | Antibody agains phosphorylated Tyrosine for the detection of protein phosphorylation in carcinoma signaling pathways | 
| Application Number | Priority Date | Filing Date | Title | 
|---|---|---|---|
| US71304105P | 2005-08-31 | 2005-08-31 | |
| PCT/US2006/033991WO2007027867A2 (en) | 2005-08-31 | 2006-08-31 | Reagents for the detection of protein phosphorylation in carcinoma signaling pathways | 
| Publication Number | Publication Date | 
|---|---|
| EP1929003A2 EP1929003A2 (en) | 2008-06-11 | 
| EP1929003A4true EP1929003A4 (en) | 2009-04-29 | 
| Application Number | Title | Priority Date | Filing Date | 
|---|---|---|---|
| EP06814000AWithdrawnEP1929003A4 (en) | 2005-08-31 | 2006-08-31 | Reagents for the detection of protein phosphorylation in carcinoma signaling pathways | 
| EP10151010AWithdrawnEP2182057A1 (en) | 2005-08-31 | 2006-08-31 | Antibody agains phosphorylated Tyrosine for the detection of protein phosphorylation in carcinoma signaling pathways | 
| Application Number | Title | Priority Date | Filing Date | 
|---|---|---|---|
| EP10151010AWithdrawnEP2182057A1 (en) | 2005-08-31 | 2006-08-31 | Antibody agains phosphorylated Tyrosine for the detection of protein phosphorylation in carcinoma signaling pathways | 
| Country | Link | 
|---|---|
| EP (2) | EP1929003A4 (en) | 
| WO (1) | WO2007027867A2 (en) | 
| Publication number | Priority date | Publication date | Assignee | Title | 
|---|---|---|---|---|
| DE10254601A1 (en) | 2002-11-22 | 2004-06-03 | Ganymed Pharmaceuticals Ag | Gene products differentially expressed in tumors and their use | 
| DE102004024617A1 (en) | 2004-05-18 | 2005-12-29 | Ganymed Pharmaceuticals Ag | Differentially expressed in tumors gene products and their use | 
| EP1790664A1 (en) | 2005-11-24 | 2007-05-30 | Ganymed Pharmaceuticals AG | Monoclonal antibodies against claudin-18 for treatment of cancer | 
| WO2008030543A2 (en)* | 2006-09-08 | 2008-03-13 | Cell Signaling Technology, Inc. | Tyrosine, serine and threonine phosphorylation sites | 
| EP1983002A3 (en)* | 2007-04-19 | 2009-03-11 | Peter Hornbeck | Tyrosine phosphorylation sites and antibodies specific for them | 
| WO2010008838A2 (en) | 2008-06-23 | 2010-01-21 | Perkinelmer Health Sciences, Inc. | Kinase substrates | 
| WO2013052686A1 (en) | 2011-10-04 | 2013-04-11 | Expression Pathology, Inc. | Srm/mrm assay for the receptor tyrosine-protein kinase erbb-4 protein (her4) | 
| WO2013167153A1 (en)* | 2012-05-09 | 2013-11-14 | Ganymed Pharmaceuticals Ag | Antibodies useful in cancer diagnosis | 
| WO2013174404A1 (en) | 2012-05-23 | 2013-11-28 | Ganymed Pharmaceuticals Ag | Combination therapy involving antibodies against claudin 18.2 for treatment of cancer | 
| NZ707831A (en) | 2012-11-13 | 2018-11-30 | Astellas Pharma Inc | Agents for treatment of claudin expressing cancer diseases | 
| WO2014127785A1 (en) | 2013-02-20 | 2014-08-28 | Ganymed Pharmaceuticals Ag | Combination therapy involving antibodies against claudin 18.2 for treatment of cancer | 
| WO2014146672A1 (en) | 2013-03-18 | 2014-09-25 | Ganymed Pharmaceuticals Ag | Therapy involving antibodies against claudin 18.2 for treatment of cancer | 
| WO2022103990A1 (en)* | 2020-11-12 | 2022-05-19 | Phosfish Llc | Methods of modifying phosphorylated or sulfated tyrosine residues of polypeptides | 
| Publication number | Priority date | Publication date | Assignee | Title | 
|---|---|---|---|---|
| WO2007133702A2 (en)* | 2006-05-12 | 2007-11-22 | Cell Signaling Technology, Inc. | Reagents for the detection of protein acetylation signaling pathways | 
| Publication number | Priority date | Publication date | Assignee | Title | 
|---|---|---|---|---|
| US4376110A (en) | 1980-08-04 | 1983-03-08 | Hybritech, Incorporated | Immunometric assays using monoclonal antibodies | 
| US4474893A (en) | 1981-07-01 | 1984-10-02 | The University of Texas System Cancer Center | Recombinant monoclonal antibodies | 
| US4659678A (en) | 1982-09-29 | 1987-04-21 | Serono Diagnostics Limited | Immunoassay of antigens | 
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations | 
| US4727022A (en) | 1984-03-14 | 1988-02-23 | Syntex (U.S.A.) Inc. | Methods for modulating ligand-receptor interactions and their application | 
| US4676980A (en) | 1985-09-23 | 1987-06-30 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Target specific cross-linked heteroantibodies | 
| US5675063A (en) | 1995-02-28 | 1997-10-07 | Loyola University Of Chicago | Immortalized rabbit hybridoma fusion partner | 
| US7198896B2 (en) | 1998-09-04 | 2007-04-03 | Cell Signaling Technology, Inc. | Immunoaffinity isolation of modified peptides from complex mixtures | 
| CA2457695A1 (en) | 2001-08-14 | 2003-02-27 | President And Fellows Of Harvard College | Absolute quantification of proteins and modified forms thereof by multistage mass spectrometry | 
| JP2003088388A (en)* | 2001-09-14 | 2003-03-25 | Herikkusu Kenkyusho:Kk | NEW FULL-LENGTH cDNA | 
| WO2005035003A2 (en)* | 2003-09-22 | 2005-04-21 | Dihedron Corporation | Compositions and methods for increasing drug efficiency | 
| Publication number | Priority date | Publication date | Assignee | Title | 
|---|---|---|---|---|
| WO2007133702A2 (en)* | 2006-05-12 | 2007-11-22 | Cell Signaling Technology, Inc. | Reagents for the detection of protein acetylation signaling pathways | 
| Title | 
|---|
| ALBERTA J A ET AL: "Generation and utilization of phosphorylation state-specific antibodies to investigate signaling pathways.", CURRENT PROTOCOLS IN NEUROSCIENCE / EDITORIAL BOARD, JACQUELINE N. CRAWLEY ... [ET AL.] MAY 2001, vol. Chapter 3, May 2001 (2001-05-01), pages Unit 3.14, XP002518938, ISSN: 1934-8576* | 
| MANDELL J W: "Phosphorylation state-specific antibodies: applications in investigative and diagnostic pathology", AMERICAN JOURNAL OF PATHOLOGY, AMERICAN SOCIETY FOR INVESTIGATIVE PATHOLOGY, US, vol. 163, no. 5, 1 November 2003 (2003-11-01), pages 1687 - 1698, XP003017035, ISSN: 0002-9440* | 
| OGAWA R ET AL: "INCREASE OF PHOSPHOTYROSINE-CONTAINING PROTEINS IN HUMAN CARCINOMAS", JAPANESE JOURNAL OF CANCER RESEARCH, JAPANESE CANCER ASSOCIATION, TOKYO, JP, vol. 76, no. 11, 1 January 1985 (1985-01-01), pages 1049 - 1055, XP009113485, ISSN: 0910-5050* | 
| PULFORD KAREN ET AL: "Immunohistochemical screening for oncogenic tyrosine kinase activation", JOURNAL OF PATHOLOGY, vol. 187, no. 5, April 1999 (1999-04-01), pages 588 - 593, XP002518937, ISSN: 0022-3417* | 
| Publication number | Publication date | 
|---|---|
| EP1929003A2 (en) | 2008-06-11 | 
| WO2007027867A3 (en) | 2007-12-21 | 
| EP2182057A1 (en) | 2010-05-05 | 
| WO2007027867A2 (en) | 2007-03-08 | 
| Publication | Publication Date | Title | 
|---|---|---|
| EP1929003A4 (en) | Reagents for the detection of protein phosphorylation in carcinoma signaling pathways | |
| EP2036119A4 (en) | Three-dimensional integrated circuit for analyte detection | |
| EP1974199A4 (en) | Detection system | |
| IL178823A0 (en) | Platelet biomarkers for the detection of disease | |
| EP1908496A4 (en) | Position detection system | |
| GB0724881D0 (en) | Methods for the detection of colorectal cancer | |
| EP1932463A4 (en) | Position detection system | |
| ZA200710297B (en) | Method for the segmentation of leukocytes | |
| IL181842A0 (en) | Multi-threat detection system | |
| EP1883045A4 (en) | Signal processor | |
| GB0519968D0 (en) | Object detection | |
| EP2126580A4 (en) | Reagents for the detection of protein phosphorylation in leukemia signaling pathways | |
| EP1950554A4 (en) | Mixture identifying system | |
| PL2140269T3 (en) | Protein signature/markers for the detection of adenocarcinoma | |
| ZA200709269B (en) | Protein kinase inhibitors | |
| EP1958341A4 (en) | Echo detection | |
| DE602005011891D1 (en) | System for detecting three-dimensional objects | |
| GB0607712D0 (en) | Detection assay | |
| EP1845838A4 (en) | Knowledge determination system | |
| EP1943500A4 (en) | Sensing system | |
| EP1934373A4 (en) | Salivary protein and rna for breast cancer detection | |
| GB0504552D0 (en) | Signal detection techniques | |
| GB0510916D0 (en) | Detection system | |
| EP1934614A4 (en) | Reagents for the detection of protein phosphorylation in carcinoma signaling pathways | |
| GB0412410D0 (en) | Protein detection | 
| Date | Code | Title | Description | 
|---|---|---|---|
| PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase | Free format text:ORIGINAL CODE: 0009012 | |
| 17P | Request for examination filed | Effective date:20080320 | |
| AK | Designated contracting states | Kind code of ref document:A2 Designated state(s):AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR | |
| AX | Request for extension of the european patent | Extension state:AL BA HR MK RS | |
| RIN1 | Information on inventor provided before grant (corrected) | Inventor name:SPEK, ERIK Inventor name:MORITZ, ALBRECHT Inventor name:LI, YU Inventor name:RIKOVA, KLARISA Inventor name:GUO, AILAN Inventor name:FARNSWORTH, CHARLES Inventor name:LEE, KIMBERLY Inventor name:POLAKIEWICZ, ROBERTO | |
| A4 | Supplementary search report drawn up and despatched | Effective date:20090330 | |
| 17Q | First examination report despatched | Effective date:20090708 | |
| STAA | Information on the status of an ep patent application or granted ep patent | Free format text:STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN | |
| 18D | Application deemed to be withdrawn | Effective date:20100119 |