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EP1693182A3 - Method and apparatus for the trial pressing of multi-layer tablets or coated tablets - Google Patents

Method and apparatus for the trial pressing of multi-layer tablets or coated tabletsDownload PDF

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Publication number
EP1693182A3
EP1693182A3EP20060002217EP06002217AEP1693182A3EP 1693182 A3EP1693182 A3EP 1693182A3EP 20060002217EP20060002217EP 20060002217EP 06002217 AEP06002217 AEP 06002217AEP 1693182 A3EP1693182 A3EP 1693182A3
Authority
EP
European Patent Office
Prior art keywords
layer
pair
filling
tablets
pressing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP20060002217
Other languages
German (de)
French (fr)
Other versions
EP1693182B1 (en
EP1693182A2 (en
Inventor
Ingo Schmidt
Ulrich Gathmann
Bernd Malner
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fette GmbH
Original Assignee
Fette GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fette GmbHfiledCriticalFette GmbH
Publication of EP1693182A2publicationCriticalpatent/EP1693182A2/en
Publication of EP1693182A3publicationCriticalpatent/EP1693182A3/en
Application grantedgrantedCritical
Publication of EP1693182B1publicationCriticalpatent/EP1693182B1/en
Not-in-forcelegal-statusCriticalCurrent
Anticipated expirationlegal-statusCritical

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Abstract

Translated fromGerman

Verfahren und Vorrichtung zur Versuchspressung von aus n Schichten bestehenden Tabletten in einer Rundläufer-Tablettenpresse.Method and apparatus for the pilot squeezing of n-layer tablets in a rotary tablet press.

Der mit einem Ober- und Unterstempel (Stempelpaar) versehene Rotor (10) wird mit dem Stempelpaar in eine definierte Füllposition gebracht, in der die dem Stempelpaar (30,32) zugeordnete Matrizenbohrung (14) mit dem Material der ersten Schicht der Tablette gefüllt wird, wobei die Füllkurve (38) in eine erste Position, die Auswerferkurve (44) in eine untere Position und Druckrollen in eine erste Pressposition durch zugeordnete Verstellantriebe gebracht werden; anschließend wird der Rotor (10) um eine volle Umdrehung gedreht und das Stempelpaar (30,32) in der Füllposition gestoppt; die Füllkurve (38) wird in eine zweite Füllposition, die Auswerferkurve (44) in die Auswerfposition und die Druckrollen in eine zweite Pressposition verstellt; danach wird die erste Schicht enthaltende Matrizenbohrung (14) mit dem Material der zweiten Schicht befüllt usw.; bei der n-ten Umdrehung wird vom Unterstempel (32) die n Schichttablette ausgeworfen.

Figure imgaf001
The provided with an upper and lower punch (pair of stamps) rotor (10) is brought with the pair of stamps in a defined filling position in which the die pair (30,32) associated with the die bore (14) is filled with the material of the first layer of the tablet wherein the filling curve (38) in a first position, the Auswerferkurve (44) are brought into a lower position and pressure rollers in a first pressing position by associated adjusting drives; then the rotor (10) is rotated by one complete revolution and the pair of punches (30, 32) are stopped in the filling position; the filling curve (38) is moved to a second filling position, the Auswerferkurve (44) in the ejection position and the pressure rollers in a second pressing position; thereafter, the stencil bore (14) containing the first layer is filled with the material of the second layer, etc .; at the nth rotation, the n-layer tablet is ejected from the lower punch (32).
Figure imgaf001

EP200600022172005-02-192006-02-03Method and apparatus for the trial pressing of multi-layer tablets or coated tabletsNot-in-forceEP1693182B1 (en)

Applications Claiming Priority (1)

Application NumberPriority DateFiling DateTitle
DE200510007790DE102005007790B4 (en)2005-02-192005-02-19 Method and device for the test extrusion of multilayer tablets or coated tablets

Publications (3)

Publication NumberPublication Date
EP1693182A2 EP1693182A2 (en)2006-08-23
EP1693182A3true EP1693182A3 (en)2008-07-30
EP1693182B1 EP1693182B1 (en)2013-12-11

Family

ID=36129760

Family Applications (1)

Application NumberTitlePriority DateFiling Date
EP20060002217Not-in-forceEP1693182B1 (en)2005-02-192006-02-03Method and apparatus for the trial pressing of multi-layer tablets or coated tablets

Country Status (3)

CountryLink
US (2)US8119045B2 (en)
EP (1)EP1693182B1 (en)
DE (1)DE102005007790B4 (en)

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DE102005007790B4 (en)2005-02-192007-06-28Fette Gmbh Method and device for the test extrusion of multilayer tablets or coated tablets
JP2008539047A (en)2005-04-282008-11-13プロテウス バイオメディカル インコーポレイテッド Pharma Informatics System
US8802183B2 (en)2005-04-282014-08-12Proteus Digital Health, Inc.Communication system with enhanced partial power source and method of manufacturing same
DE102005030312B4 (en)*2005-06-232011-05-05Korsch Ag Rotary tabletting machine and method for producing a multilayer tablet
WO2008016183A1 (en)*2006-08-042008-02-07Brother Kogyo Kabushiki KaishaImage forming apparatus
KR101677698B1 (en)2009-04-282016-11-21프로테우스 디지털 헬스, 인코포레이티드Highly reliable ingestible event markers and methods for using the same
UA109424C2 (en)*2009-12-022015-08-25 PHARMACEUTICAL PRODUCT, PHARMACEUTICAL TABLE WITH ELECTRONIC MARKER AND METHOD OF MANUFACTURING PHARMACEUTICAL TABLETS
KR20170121299A (en)2010-04-072017-11-01프로테우스 디지털 헬스, 인코포레이티드Miniature ingestible device
WO2012071280A2 (en)2010-11-222012-05-31Proteus Biomedical, Inc.Ingestible device with pharmaceutical product
DE102011101286B4 (en)*2011-05-102013-10-17Fette Compacting Gmbh Rotary press and method for operating a rotary press
US9756874B2 (en)2011-07-112017-09-12Proteus Digital Health, Inc.Masticable ingestible product and communication system therefor
WO2015112603A1 (en)2014-01-212015-07-30Proteus Digital Health, Inc.Masticable ingestible product and communication system therefor
US11149123B2 (en)2013-01-292021-10-19Otsuka Pharmaceutical Co., Ltd.Highly-swellable polymeric films and compositions comprising the same
US10175376B2 (en)2013-03-152019-01-08Proteus Digital Health, Inc.Metal detector apparatus, system, and method
US9796576B2 (en)2013-08-302017-10-24Proteus Digital Health, Inc.Container with electronically controlled interlock
US10084880B2 (en)2013-11-042018-09-25Proteus Digital Health, Inc.Social media networking based on physiologic information
EP2977195A1 (en)*2014-07-212016-01-27M & R Automation GmbHApparatus and method of manufacturing multiple-layer tablets
US11051543B2 (en)2015-07-212021-07-06Otsuka Pharmaceutical Co. Ltd.Alginate on adhesive bilayer laminate film
US10187121B2 (en)2016-07-222019-01-22Proteus Digital Health, Inc.Electromagnetic sensing and detection of ingestible event markers
IL265827B2 (en)2016-10-262023-03-01Proteus Digital Health IncMethods for manufacturing capsules with ingestible event markers
CN110150707A (en)*2017-12-282019-08-23浙江东来天然生物制品有限公司Strip food molding equipment
CN108572602B (en)*2018-07-232024-03-15上海海得控制系统股份有限公司Control device of tablet press
NL2021552B1 (en)*2018-09-032020-04-30Besi Netherlands BvMethod and device for selective separating electronic components from a frame with electronic components

Citations (2)

* Cited by examiner, † Cited by third party
Publication numberPriority datePublication dateAssigneeTitle
EP0572816A1 (en)*1992-06-021993-12-08Wilhelm Fette GmbHProcess and apparatus for making double-layered tablets on a two station rotary press
DE10319024B3 (en)*2003-04-282004-08-12Fette GmbhProcess for pressing tablets comprises automatically moving a stamping pair to a filling position, filling a die with a material while keeping the rotor still

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication numberPriority datePublication dateAssigneeTitle
BE569198A (en)*1957-07-12
US4139589A (en)*1975-02-261979-02-13Monique BeringerProcess for the manufacture of a multi-zone tablet and tablet manufactured by this process
DE2742572B1 (en)*1977-09-221979-03-29Fette Wilhelm Gmbh Method of making tablets and tablet press
DE3520203A1 (en)*1985-06-051986-12-11Wilhelm Fette Gmbh, 2053 Schwarzenbek ROTARY ROTARY TABLETING MACHINE AND METHOD FOR CONTROLLING YOUR PRINT ROLLERS
US4880373A (en)*1988-04-281989-11-14The Upjohn CompanyTablet press
US5223192A (en)*1989-12-021993-06-29Firma Wilhelm Fette GmbhMethod of and arrangement for monitoring pressing forces in a pelletizing machine
DE3939956A1 (en)*1989-12-021991-06-06Fette Wilhelm Gmbh METHOD AND DEVICE FOR MONITORING THE PRESSING FORCE OF A TABLETING MACHINE
US5322655A (en)*1993-02-191994-06-21Thomas Engineering, Inc.Method for monitoring and controlling the weights of each layer of a multilayer tablet
DE19844390B4 (en)*1998-09-282005-09-22Wilhelm Fette Gmbh Process for producing tablets in a rotary tablet machine
DE19964225C2 (en)*1999-12-172002-01-24Henkel Kgaa Pressing process for multi-phase moldings
DE10161572B4 (en)*2001-12-142004-03-25Wilhelm Fette Gmbh Tablet press machine
DE10202820C1 (en)*2002-01-252003-03-13Fette Wilhelm GmbhSet of punches and/or dies for tablet presses is provided with encoded information covering at least the identity of the set, the identity of each punch or die, and their critical dimensions
DE10207764B4 (en)*2002-02-232005-11-17Wilhelm Fette Gmbh Method for controlling the assembly of individual components and / or assemblies of a tableting machine
DE102005007790B4 (en)2005-02-192007-06-28Fette Gmbh Method and device for the test extrusion of multilayer tablets or coated tablets

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication numberPriority datePublication dateAssigneeTitle
EP0572816A1 (en)*1992-06-021993-12-08Wilhelm Fette GmbHProcess and apparatus for making double-layered tablets on a two station rotary press
DE10319024B3 (en)*2003-04-282004-08-12Fette GmbhProcess for pressing tablets comprises automatically moving a stamping pair to a filling position, filling a die with a material while keeping the rotor still

Also Published As

Publication numberPublication date
US8119045B2 (en)2012-02-21
DE102005007790B4 (en)2007-06-28
US20120195992A1 (en)2012-08-02
US20060186568A1 (en)2006-08-24
US8382465B2 (en)2013-02-26
DE102005007790A1 (en)2006-08-24
EP1693182B1 (en)2013-12-11
EP1693182A2 (en)2006-08-23

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