| IT1024076B (en)* | 1974-11-06 | 1978-06-20 | Marinello Rosolino | EQUIPMENT OCADILVANTE THE TREATMENT OF INJURIES OR INFLAMMATIONS INTERNAL TO THE HUMAN BODY |
| GB1519149A (en)* | 1974-11-30 | 1978-07-26 | Fisons Ltd | Devices for administering medicaments |
| DE2953373A1 (en)* | 1978-12-06 | 1981-01-08 | P Svedman | Device for treating tissues,for example skin |
| US4439199A (en)* | 1980-02-19 | 1984-03-27 | Alza Corporation | Method for administering immunopotentiator |
| US4455142A (en)* | 1980-07-07 | 1984-06-19 | Alza Corporation | Method of coadministering an antigen and an immunopotentiator |
| US4340048A (en)* | 1981-03-28 | 1982-07-20 | Alza Corporation | Self-driven hypodermic injector |
| US4460368A (en)* | 1981-10-29 | 1984-07-17 | Almedco, Inc. | Trans-dermal medication system |
| US4460370A (en)* | 1981-10-29 | 1984-07-17 | Almedco, Inc. | Trans-dermal medication application cell |
| US4473083A (en)* | 1981-12-14 | 1984-09-25 | Maganias Nicholas H | Device and method for allergy testing |
| US4802493A (en)* | 1981-12-14 | 1989-02-07 | Maganias Nicholas H | Device and method for allergy testing |
| DE3274422D1 (en)* | 1981-12-14 | 1987-01-15 | Nicholas H Maganias | Device and method for allergy testing |
| US4484923A (en)* | 1982-03-25 | 1984-11-27 | Alza Corporation | Method for administering immunopotentiator |
| US4435180A (en)* | 1982-05-25 | 1984-03-06 | Alza Corporation | Elastomeric active agent delivery system and method of use |
| IE53703B1 (en)* | 1982-12-13 | 1989-01-18 | Elan Corp Plc | Drug delivery device |
| FR2562800A1 (en)* | 1984-04-11 | 1985-10-18 | Fournier Laboratoires | Device for percutaneous administration of medicaments |
| US5122127A (en)* | 1985-05-01 | 1992-06-16 | University Of Utah | Apparatus and methods for use in administering medicaments by direct medicament contact to mucosal tissues |
| US4655766A (en)* | 1985-08-01 | 1987-04-07 | Alza Corporation | Fluid imbibing pump with self-regulating skin patch |
| EP0257086B1 (en)* | 1986-01-31 | 1993-01-20 | WHITBY RESEARCH, Inc. | Skinpenetration enhancing compositions |
| US5204339A (en)* | 1986-01-31 | 1993-04-20 | Whitby Research, Inc. | Penetration enhancers for transdermal delivery of systemic agents |
| US4787888A (en)* | 1987-06-01 | 1988-11-29 | University Of Connecticut | Disposable piezoelectric polymer bandage for percutaneous delivery of drugs and method for such percutaneous delivery (a) |
| DE3726617C1 (en)* | 1987-08-11 | 1988-07-07 | Friedrichsfeld Gmbh | Wound covering |
| US4879275A (en)* | 1987-09-30 | 1989-11-07 | Nelson Research & Development Co. | Penetration enhancers for transdermal delivery of systemic agent |
| US4920101A (en)* | 1987-09-30 | 1990-04-24 | Nelson Research & Development Co. | Compositions comprising 1-oxo- or thiohydrocarbyl substituted azacycloaklkanes |
| GB2221394B (en)* | 1988-08-05 | 1992-03-04 | Eilert Eilertsen | An injection device |
| US5697901A (en)* | 1989-12-14 | 1997-12-16 | Elof Eriksson | Gene delivery by microneedle injection |
| US5661132A (en)* | 1989-12-14 | 1997-08-26 | Auragen, Inc. | Wound healing |
| US5423778A (en)* | 1989-12-14 | 1995-06-13 | Elof Eriksson | System and method for transplantation of cells |
| US5060642A (en)* | 1990-01-05 | 1991-10-29 | Gilman Thomas H | Wound dressing with air permeable bacteria impermeable reservoir |
| FI941336L (en)* | 1993-03-23 | 1994-09-24 | Diomedes Oy | A patch that acts as a dispensing device |
| CA2092731A1 (en)* | 1993-03-26 | 1994-09-27 | Yaping Shen | Mirror amide cord factors and mirror thioesther cord factors for diagnosis of tuberculosis |
| US7422574B2 (en)* | 1995-05-19 | 2008-09-09 | Applied Tissue Technologies, Llc | Microseeding device for gene delivery by microneedle injection |
| WO1996037256A1 (en)* | 1995-05-22 | 1996-11-28 | Silicon Microdevices, Inc. | Micromechanical patch for enhancing the delivery of compounds through the skin |
| US8801681B2 (en) | 1995-09-05 | 2014-08-12 | Argentum Medical, Llc | Medical device |
| US6861570B1 (en)* | 1997-09-22 | 2005-03-01 | A. Bart Flick | Multilayer conductive appliance having wound healing and analgesic properties |
| US5814094A (en) | 1996-03-28 | 1998-09-29 | Becker; Robert O. | Iontopheretic system for stimulation of tissue healing and regeneration |
| US8455710B2 (en)* | 1997-09-22 | 2013-06-04 | Argentum Medical, Llc | Conductive wound dressings and methods of use |
| US7214847B1 (en) | 1997-09-22 | 2007-05-08 | Argentum Medical, L.L.C. | Multilayer conductive appliance having wound healing and analgesic properties |
| US7094422B2 (en)* | 1996-02-19 | 2006-08-22 | Acrux Dds Pty Ltd. | Topical delivery of antifungal agents |
| AUPN814496A0 (en) | 1996-02-19 | 1996-03-14 | Monash University | Dermal penetration enhancer |
| ZA975326B (en)* | 1996-06-18 | 1998-01-14 | Alza Corp | Device and method for enhancing transdermal flux of agents being delivered or sampled. |
| DE69718495T2 (en)* | 1996-09-17 | 2003-11-20 | Deka Products Ltd. Partnership, Manchester | SYSTEM FOR DISPOSAL OF MEDICINE BY TRANSPORT |
| US6918901B1 (en) | 1997-12-10 | 2005-07-19 | Felix Theeuwes | Device and method for enhancing transdermal agent flux |
| ATE221400T1 (en)* | 1997-12-11 | 2002-08-15 | Alza Corp | DEVICE FOR INCREASE THE TRANSDERMAL FLOW OF ACTIVE INGREDIENTS |
| PT1037686E (en)* | 1997-12-11 | 2005-10-31 | Alza Corp | APPARATUS FOR POTENTIATING THE FLOW OF TRANSDERMMIC AGENT |
| EP1911488A3 (en) | 1997-12-11 | 2008-12-03 | Alza Corporation | Device for enhancing transdermal agent flux |
| CA2313700C (en) | 1997-12-11 | 2009-11-24 | Alza Corporation | Device for enhancing transdermal agent flux |
| US6091975A (en)* | 1998-04-01 | 2000-07-18 | Alza Corporation | Minimally invasive detecting device |
| USD526409S1 (en) | 1998-07-14 | 2006-08-08 | Unomedical A/S | Medical puncturing device |
| US6623457B1 (en)* | 1999-09-22 | 2003-09-23 | Becton, Dickinson And Company | Method and apparatus for the transdermal administration of a substance |
| US20020095134A1 (en)* | 1999-10-14 | 2002-07-18 | Pettis Ronald J. | Method for altering drug pharmacokinetics based on medical delivery platform |
| US8465468B1 (en)* | 2000-06-29 | 2013-06-18 | Becton, Dickinson And Company | Intradermal delivery of substances |
| US20020156453A1 (en)* | 1999-10-14 | 2002-10-24 | Pettis Ronald J. | Method and device for reducing therapeutic dosage |
| PT1239917E (en) | 1999-12-10 | 2005-08-31 | Alza Corp | CUTANEOUS TREATMENT DEVICE FOR PROLONGED TRANSDERMIC ADMINISTRATION OF A MEDICINE |
| DE60024312T2 (en) | 1999-12-10 | 2006-08-17 | Alza Corp., Mountain View | Transdermal drug delivery of macromolecular agents and device therefor |
| WO2001043643A1 (en) | 1999-12-16 | 2001-06-21 | Alza Corporation | Device for enhancing transdermal flux of sampled agents |
| US20050277887A1 (en)* | 2000-05-08 | 2005-12-15 | Joel Douglas | Micro infusion drug delivery device |
| US6629949B1 (en)* | 2000-05-08 | 2003-10-07 | Sterling Medivations, Inc. | Micro infusion drug delivery device |
| US6659982B2 (en) | 2000-05-08 | 2003-12-09 | Sterling Medivations, Inc. | Micro infusion drug delivery device |
| US20040175360A1 (en)* | 2000-06-29 | 2004-09-09 | Pettis Ronald J. | Method for altering drug pharmacokinetics based on medical delivery platform |
| US20050008683A1 (en)* | 2000-06-29 | 2005-01-13 | Becton Dickinson And Company | Method for delivering interferons to the intradermal compartment |
| US6690959B2 (en) | 2000-09-01 | 2004-02-10 | Medtronic, Inc. | Skin-mounted electrodes with nano spikes |
| DK1335711T3 (en) | 2000-09-08 | 2007-11-26 | Alza Corp | Transdermal device |
| AU2001293460A1 (en)* | 2000-10-05 | 2002-04-15 | Thomas Marsoner | Medical injection device |
| WO2002030506A2 (en) | 2000-10-12 | 2002-04-18 | Ink Jet Technology Ltd. | Transdermal method |
| PL360977A1 (en) | 2000-10-13 | 2004-09-20 | Alza Corporation | Microprotrusion member retainer for impact applicator |
| CA2425537C (en)* | 2000-10-13 | 2009-09-08 | Alza Corporation | Microblade array impact applicator |
| PL360998A1 (en)* | 2000-10-13 | 2004-09-20 | Alza Corporation | Apparatus and method for piercing skin with microprotrusions |
| US7419481B2 (en)* | 2000-10-13 | 2008-09-02 | Alza Corporation | Apparatus and method for piercing skin with microprotrusions |
| US7828827B2 (en) | 2002-05-24 | 2010-11-09 | Corium International, Inc. | Method of exfoliation of skin using closely-packed microstructures |
| US6821281B2 (en)* | 2000-10-16 | 2004-11-23 | The Procter & Gamble Company | Microstructures for treating and conditioning skin |
| HUP0302924A2 (en)* | 2000-10-26 | 2003-12-29 | Alza Corp | Transdermal drug delivery devices having coated microprotrusions |
| WO2002074336A2 (en)* | 2001-02-23 | 2002-09-26 | Glaxosmithkline Biologicals S.A. | Influenza vaccine formulations for intradermal delivery |
| US20040096463A1 (en)* | 2001-02-23 | 2004-05-20 | Nathalie Garcon | Novel vaccine |
| WO2002074173A1 (en)* | 2001-03-16 | 2002-09-26 | Alza Corporation | Method and apparatus for coating skin piercing microprojections |
| CA2444391A1 (en)* | 2001-04-13 | 2002-10-24 | Becton Dickinson And Company | Methods and devices for administration of substances into the intradermal layer of skin for systemic absorption |
| EP3251722B1 (en) | 2001-04-20 | 2020-06-17 | ALZA Corporation | Microprojection array having a beneficial agent containing coating and method of forming the coating thereon |
| KR20040020889A (en)* | 2001-04-20 | 2004-03-09 | 알자 코포레이션 | Microprojection array having a beneficial agent containing coating |
| US20020193729A1 (en)* | 2001-04-20 | 2002-12-19 | Cormier Michel J.N. | Microprojection array immunization patch and method |
| EP1381344A4 (en)* | 2001-04-27 | 2008-06-11 | Glaxosmithkline Biolog Sa | Novel vaccine |
| US20030073609A1 (en)* | 2001-06-29 | 2003-04-17 | Pinkerton Thomas C. | Enhanced pharmacokinetic profile of intradermally delivered substances |
| MXPA03011611A (en)* | 2001-06-29 | 2004-07-01 | Becton Dickinson Co | Intradermal delivery of vaccines and gene therapeutic agents via microcannula. |
| US20050010193A1 (en)* | 2002-05-06 | 2005-01-13 | Laurent Philippe E. | Novel methods for administration of drugs and devices useful thereof |
| US8920375B2 (en)* | 2001-09-21 | 2014-12-30 | Valeritas, Inc. | Gas pressure actuated microneedle arrays, and systems and methods relating to same |
| US6830562B2 (en) | 2001-09-27 | 2004-12-14 | Unomedical A/S | Injector device for placing a subcutaneous infusion set |
| US7429258B2 (en)* | 2001-10-26 | 2008-09-30 | Massachusetts Institute Of Technology | Microneedle transport device |
| US20040120964A1 (en)* | 2001-10-29 | 2004-06-24 | Mikszta John A. | Needleless vaccination using chimeric yellow fever vaccine-vectored vaccines against heterologous flaviviruses |
| ATE323526T1 (en) | 2002-02-12 | 2006-05-15 | Unomedical As | INFUSION DEVICE WITH NEEDLE PROTECTIVE SLEEVE |
| EP3351277A1 (en) | 2002-03-26 | 2018-07-25 | Becton, Dickinson and Company | Multi-stage fluid delivery device and method |
| US6780171B2 (en) | 2002-04-02 | 2004-08-24 | Becton, Dickinson And Company | Intradermal delivery device |
| US7115108B2 (en)* | 2002-04-02 | 2006-10-03 | Becton, Dickinson And Company | Method and device for intradermally delivering a substance |
| JP4764626B2 (en)* | 2002-05-06 | 2011-09-07 | ベクトン・ディキンソン・アンド・カンパニー | Method and device for controlling the pharmacokinetics of a drug |
| US20060264886A9 (en)* | 2002-05-06 | 2006-11-23 | Pettis Ronald J | Method for altering insulin pharmacokinetics |
| US6945952B2 (en)* | 2002-06-25 | 2005-09-20 | Theraject, Inc. | Solid solution perforator for drug delivery and other applications |
| KR20050054483A (en)* | 2002-06-28 | 2005-06-10 | 알자 코포레이션 | Transdermal drug delivery devices having coated microprotrusions |
| CA2493728C (en)* | 2002-07-22 | 2013-10-29 | Becton, Dickinson And Company | Patch-like infusion device |
| TW200409657A (en)* | 2002-08-08 | 2004-06-16 | Alza Corp | Transdermal vaccine delivery device having coated microprotrusions |
| BR0313890A (en)* | 2002-08-30 | 2005-07-26 | Becton Dickinson Co | Pharmacokinetic control method of immunomodulatory compounds |
| US7594909B2 (en) | 2002-09-02 | 2009-09-29 | Unomedical, A/S | Apparatus and method for adjustment of the length of an infusion tubing |
| US20040051019A1 (en)* | 2002-09-02 | 2004-03-18 | Mogensen Lasse Wesseltoft | Apparatus for and a method of adjusting the length of an infusion tube |
| AU2003258486A1 (en) | 2002-09-02 | 2004-03-19 | Unomedical A/S | A device for subcutaneous administration of a medicament to a patient and tubing for same |
| ATE419034T1 (en) | 2002-09-02 | 2009-01-15 | Unomedical As | DEVICE FOR SUBCUTANEOUS ADMINISTRATION OF A MEDICATION TO A PATIENT |
| WO2004024224A1 (en)* | 2002-09-16 | 2004-03-25 | Sung-Yun Kwon | Solid micro-perforators and methods of use |
| EP1590033A2 (en)* | 2002-09-30 | 2005-11-02 | Alza Corporation | Drug delivery device having coated microprojections incorporating vasoconstrictors |
| DK200201823A (en) | 2002-11-26 | 2004-05-27 | Maersk Medical As | Connection piece for a hose connection |
| AR042815A1 (en)* | 2002-12-26 | 2005-07-06 | Alza Corp | ACTIVE AGENT SUPPLY DEVICE THAT HAS COMPOUND MEMBERS |
| US20040158202A1 (en)* | 2003-02-12 | 2004-08-12 | Soren Jensen | Cover |
| US7070580B2 (en)* | 2003-04-01 | 2006-07-04 | Unomedical A/S | Infusion device and an adhesive sheet material and a release liner |
| US20050163711A1 (en)* | 2003-06-13 | 2005-07-28 | Becton, Dickinson And Company, Inc. | Intra-dermal delivery of biologically active agents |
| CN1842320B (en) | 2003-06-30 | 2013-06-19 | 阿尔扎公司 | Formulations for coated microprojections containing non-volatile counterions |
| US20050123507A1 (en)* | 2003-06-30 | 2005-06-09 | Mahmoud Ameri | Formulations for coated microprojections having controlled solubility |
| EP1638468B1 (en)* | 2003-06-30 | 2007-08-15 | Alza Corporation | Method for coating skin piercing microprojections |
| BRPI0412202A (en)* | 2003-07-02 | 2006-08-22 | Alza Corp | immunization patch having a microprojection array, and method |
| TW200514593A (en)* | 2003-08-04 | 2005-05-01 | Alza Corp | Method and device for enhancing transdermal agent flux |
| MXPA06001467A (en)* | 2003-08-12 | 2006-05-15 | Becton Dickinson Co | Patch-like infusion device. |
| USD579541S1 (en) | 2003-10-15 | 2008-10-28 | Unomedical A/S | Medical insertion device |
| USD576267S1 (en) | 2003-10-15 | 2008-09-02 | Unomedical A/S | Medical infusion device |
| USD554253S1 (en) | 2003-10-15 | 2007-10-30 | Unomedical A/S | Medical infusion device |
| EP1680057A4 (en)* | 2003-10-24 | 2007-10-31 | Alza Corp | Apparatus and method for enhancing transdermal drug delivery |
| AU2004285484A1 (en)* | 2003-10-24 | 2005-05-12 | Alza Corporation | Pretreatment method and system for enhancing transdermal drug delivery |
| BRPI0415967A (en)* | 2003-10-28 | 2007-01-23 | Alza Corp | application of peptide polymer conjugates and therapeutic proteins through coated microprojections |
| CA2543154A1 (en)* | 2003-10-28 | 2005-05-19 | Alza Corporation | Method and apparatus for reducing the incidence of tobacco use |
| KR20060099523A (en)* | 2003-10-31 | 2006-09-19 | 알자 코포레이션 | Self-acting applicator for fine protrusion array |
| JP5388415B2 (en)* | 2003-11-13 | 2014-01-15 | アルザ・コーポレーシヨン | Compositions and devices for transdermal delivery |
| EP1682217A4 (en)* | 2003-11-13 | 2008-04-30 | Alza Corp | System and method for transdermal delivery |
| EP1686904A4 (en)* | 2003-11-21 | 2008-02-27 | Alza Corp | Ultrasound assisted transdermal vaccine delivery method and system |
| WO2005051476A1 (en)* | 2003-11-28 | 2005-06-09 | Acrux Dds Pty Ltd | Method and system for rapid transdermal administration |
| WO2005091922A2 (en)* | 2004-03-03 | 2005-10-06 | Becton, Dickinson And Company | Methods and devices for improving delivery of a substance to skin |
| CA2560840C (en)* | 2004-03-24 | 2014-05-06 | Corium International, Inc. | Transdermal delivery device |
| KR101114710B1 (en) | 2004-03-26 | 2012-02-29 | 우노메디컬 에이/에스 | Infusion set |
| JP2007537783A (en)* | 2004-04-13 | 2007-12-27 | アルザ コーポレイション | Apparatus and method for transdermal delivery of multiple vaccines |
| JP2007532645A (en)* | 2004-04-13 | 2007-11-15 | アルザ コーポレイション | Devices and methods for transdermal delivery systems of drugs based on fentanyl |
| US20050240154A1 (en)* | 2004-04-21 | 2005-10-27 | Unomedical A/S: | Infusion set with patch |
| WO2005115360A2 (en)* | 2004-05-11 | 2005-12-08 | Becton, Dickinson And Company | Formulations of anti-pain agents and methods of using the same |
| AU2005244734A1 (en)* | 2004-05-13 | 2005-12-01 | Alza Corporation | Apparatus and method for transdermal delivery of parathyroid hormone agents |
| WO2005112463A2 (en)* | 2004-05-19 | 2005-11-24 | Alza Corporation | Method and formulation for transdermal delivery of immunologically active agents |
| US20060030811A1 (en)* | 2004-08-03 | 2006-02-09 | Wong Patrick S | Method and device for enhancing transdermal agent flux |
| US8062250B2 (en) | 2004-08-10 | 2011-11-22 | Unomedical A/S | Cannula device |
| AR054300A1 (en)* | 2004-08-10 | 2007-06-20 | Alza Corp | APPARATUS AND MICROPROJECTION SYSTEM WITH INFECTIOUS POTENTIAL ESCASS |
| AR050608A1 (en)* | 2004-08-19 | 2006-11-08 | Alza Corp | APPARATUS AND METHOD FOR TRANSDERMAL ADMINISTRATION OF VASCULAR ENDOTELIAL GROWTH FACTORS |
| KR20070099540A (en)* | 2004-09-08 | 2007-10-09 | 알자 코포레이션 | Microprojection arrays with improved skin adhesion and compliance |
| WO2006037070A2 (en)* | 2004-09-28 | 2006-04-06 | Alza Corporation | Stabilization of alum-adjuvanted immunologically active agents |
| US20060093658A1 (en)* | 2004-10-26 | 2006-05-04 | Gayatri Sathyan | Apparatus and method for transdermal delivery of desmopressin |
| CN101072597B (en) | 2004-12-10 | 2010-06-16 | 优诺医疗有限公司 | Inserter |
| AR054225A1 (en)* | 2005-02-16 | 2007-06-13 | Alza Corp | APPARATUS AND METHOD FOR TRANSDERMAL SUPPLY OF EPOYETINE-BASED AGENTS |
| AU2006213994A1 (en)* | 2005-02-16 | 2006-08-24 | Alza Corporation | Microprojection arrays with improved biocompatibility |
| US20070270738A1 (en)* | 2005-04-25 | 2007-11-22 | Wu Jeffrey M | Method of treating ACNE with stratum corneum piercing patch |
| US20080009802A1 (en)* | 2005-04-25 | 2008-01-10 | Danilo Lambino | Method of treating acne with stratum corneum piercing device |
| US20060253078A1 (en)* | 2005-04-25 | 2006-11-09 | Wu Jeffrey M | Method of treating skin disorders with stratum corneum piercing device |
| US20060280645A1 (en)* | 2005-06-02 | 2006-12-14 | Scott Sellers | Method for terminal sterilization of transdermal delivery devices |
| CN101189031A (en)* | 2005-06-02 | 2008-05-28 | 阿尔扎公司 | Method for terminal sterilization of transdermal delivery devices |
| US20070009587A1 (en)* | 2005-06-21 | 2007-01-11 | Peter Daddona | Method and device for coating a continuous strip of microprojection members |
| US7621395B2 (en) | 2005-06-28 | 2009-11-24 | Unomedical A/S | Packing for infusion set and method of applying an infusion set |
| ES2478623T3 (en)* | 2005-09-06 | 2014-07-22 | Theraject, Inc. | Solid solution perforator containing drug particles and / or drug adsorbent particles |
| ES2354107T3 (en) | 2005-09-12 | 2011-03-10 | Unomedical A/S | INSERTION DEVICE FOR AN INFUSION TEAM WITH A FIRST AND SECOND SPRING UNITS. |
| US20070293814A1 (en)* | 2005-09-12 | 2007-12-20 | Trautman Joseph C | Coatable transdermal delivery microprojection assembly |
| US8153162B2 (en)* | 2005-09-27 | 2012-04-10 | Tissuetech, Inc. | Purified amniotic membrane compositions and methods of use |
| US8187639B2 (en) | 2005-09-27 | 2012-05-29 | Tissue Tech, Inc. | Amniotic membrane preparations and purified compositions and anti-angiogenesis treatment |
| MX2008006888A (en) | 2005-11-28 | 2008-09-30 | Marinus Pharmaceuticals | Ganaxolone formulations and methods for the making and use thereof. |
| USD655807S1 (en) | 2005-12-09 | 2012-03-13 | Unomedical A/S | Medical device |
| US7658728B2 (en)* | 2006-01-10 | 2010-02-09 | Yuzhakov Vadim V | Microneedle array, patch, and applicator for transdermal drug delivery |
| CA2680690A1 (en)* | 2006-03-15 | 2007-09-20 | Alza Corporation | Apparatus and method for transdermal delivery of parathyroid hormone agents to prevent or treat osteopenia |
| US20070293816A1 (en)* | 2006-04-25 | 2007-12-20 | Alza Corporation | Microprojection Array Application with Grouped Microprojections for High Drug Loading |
| US20070299388A1 (en)* | 2006-04-25 | 2007-12-27 | Alza Corporation | Microprojection array application with multilayered microprojection member for high drug loading |
| US20080090897A1 (en) | 2006-08-11 | 2008-04-17 | The Johns Hopkins University | Compositions and methods for neuroprotectin |
| HUE028086T2 (en) | 2006-09-22 | 2016-11-28 | Pharmacyclics Llc | Inhibitors of bruton's tyrosine kinase |
| US7785301B2 (en)* | 2006-11-28 | 2010-08-31 | Vadim V Yuzhakov | Tissue conforming microneedle array and patch for transdermal drug delivery or biological fluid collection |
| CA2669815A1 (en) | 2006-11-28 | 2008-06-05 | Marinus Pharmaceuticals | Nanoparticulate formulations and methods for the making and use thereof |
| CA2676221C (en) | 2007-01-22 | 2016-12-20 | Corium International, Inc. | Applicators for microneedles |
| US8940326B2 (en) | 2007-03-19 | 2015-01-27 | Vita Sciences Llc | Transdermal patch and method for delivery of vitamin B12 |
| ES2817249T3 (en) | 2007-04-16 | 2021-04-06 | Corium Inc | Microneedle matrices obtained by dissolution and casting containing an active principle |
| WO2009035818A1 (en) | 2007-09-10 | 2009-03-19 | Calcimedica, Inc. | Compounds that modulate intracellular calcium |
| WO2009048607A1 (en)* | 2007-10-10 | 2009-04-16 | Corium International, Inc. | Vaccine delivery via microneedle arrays |
| WO2009137631A2 (en)* | 2008-05-07 | 2009-11-12 | Wintherix Llc | Methods for identifying compounds that affect expression of cancer-related protein isoforms |
| CN102027133A (en)* | 2008-05-07 | 2011-04-20 | 温瑟瑞克斯有限公司 | Methods for identifying compounds that modulate Wnt signaling in cancer cells |
| JP5584202B2 (en)* | 2008-05-21 | 2014-09-03 | セラジェクト， インコーポレイテッド | Method for manufacturing solid solution punch patch and use thereof |
| WO2010027875A2 (en) | 2008-08-27 | 2010-03-11 | Calcimedica Inc. | Compounds that modulate intracellular calcium |
| WO2010071866A2 (en) | 2008-12-19 | 2010-06-24 | Nuon Therapeutics, Inc. | Combination therapy for arthritis with tranilast |
| US8617487B2 (en) | 2009-03-25 | 2013-12-31 | Venture Lending & Leasing Vi, Inc. | Saliva sample collection systems |
| EP2421901B1 (en) | 2009-04-24 | 2015-10-28 | Tissue Tech, Inc. | Compositions containing hc ha complex and methods of use thereof |
| EP2429627B1 (en)* | 2009-04-24 | 2017-06-14 | Corium International, Inc. | Methods for manufacturing microprojection arrays |
| EP2450079B1 (en) | 2009-07-01 | 2015-02-25 | Toppan Printing Co., Ltd. | Needle-like material |
| US20130018279A1 (en)* | 2009-09-01 | 2013-01-17 | Pathway Genomics | "blood sample collection apparatus and kits" |
| US7741330B1 (en) | 2009-10-12 | 2010-06-22 | Pharmacyclics, Inc. | Pyrazolo-pyrimidine inhibitors of Bruton's tyrosine kinase |
| JP5827237B2 (en) | 2009-12-16 | 2015-12-02 | ベクトン・ディキンソン・アンド・カンパニーＢｅｃｔｏｎ， Ｄｉｃｋｉｎｓｏｎ Ａｎｄ Ｃｏｍｐａｎｙ | Self injection device |
| EP2512559B1 (en) | 2009-12-16 | 2018-12-05 | Becton, Dickinson and Company | Self-injection device |
| JP5650755B2 (en) | 2009-12-16 | 2015-01-07 | ベクトン・ディキンソン・アンド・カンパニーＢｅｃｔｏｎ， Ｄｉｃｋｉｎｓｏｎ Ａｎｄ Ｃｏｍｐａｎｙ | Self injection device |
| CN102753225B (en) | 2009-12-16 | 2014-10-08 | 贝克顿·迪金森公司 | Self-injection device |
| DK2512579T3 (en) | 2009-12-16 | 2017-03-13 | Becton Dickinson Co | Self Injection Device |
| WO2011075102A1 (en) | 2009-12-16 | 2011-06-23 | Becton, Dickinson And Company | Self- injection device |
| WO2011097594A2 (en) | 2010-02-08 | 2011-08-11 | Kinagen, Inc. | Therapeutic methods and compositions involving allosteric kinase inhibition |
| GB2478363A (en)* | 2010-03-05 | 2011-09-07 | Ndm Technologies Ltd | Microneedle patch and method of manufacture |
| AU2011232372B2 (en) | 2010-03-24 | 2016-06-30 | Amitech Therapeutic Solutions, Inc. | Heterocyclic compounds useful for kinase inhibition |
| AU2011239636A1 (en) | 2010-04-13 | 2012-11-22 | Najib Babul | Dermal pharmaceutical compositions of 1-Methyl-2',6'-pipecoloxylidide and method of use |
| WO2011130689A1 (en) | 2010-04-15 | 2011-10-20 | Tracon Pharmaceuticals, Inc. | Potentiation of anti-cancer activity through combination therapy with ber pathway inhibitors |
| ES2591004T3 (en) | 2010-04-27 | 2016-11-24 | Calcimedica, Inc. | Intracellular calcium modulating compounds |
| AU2011248579A1 (en) | 2010-04-27 | 2012-11-29 | Calcimedica, Inc. | Compounds that modulate intracellular calcium |
| JP6327852B2 (en) | 2010-05-04 | 2018-05-23 | コリウム インターナショナル， インコーポレイテッド | Methods and devices for transdermal delivery of parathyroid hormone using microprojection arrays |
| ES2688072T3 (en) | 2010-05-11 | 2018-10-30 | Mallinckrodt Ard Ip Limited | ACTH for the treatment of amyotrophic lateral sclerosis |
| NZ702485A (en) | 2010-06-03 | 2016-04-29 | Pharmacyclics Llc | The use of inhibitors of bruton’s tyrosine kinase (btk) |
| JP5916149B2 (en) | 2010-08-27 | 2016-05-11 | カルシメディカ，インク． | Compounds that regulate intracellular calcium |
| JP5843862B2 (en) | 2010-09-02 | 2016-01-13 | ベクトン・ディキンソン・アンド・カンパニーＢｅｃｔｏｎ， Ｄｉｃｋｉｎｓｏｎ Ａｎｄ Ｃｏｍｐａｎｙ | Self-injection device with needle cover with anti-start device |
| US8796416B1 (en) | 2010-10-25 | 2014-08-05 | Questcor Pharmaceuticals, Inc | ACTH prophylactic treatment of renal disorders |
| US8846740B2 (en) | 2011-01-04 | 2014-09-30 | Biological Responsibility, Llc | Biotherapeutics for the treatment of infectious diseases |
| SG10201602752XA (en) | 2011-01-07 | 2016-05-30 | Allergan Inc | Melanin modification compositions and methods of use |
| WO2012149486A1 (en) | 2011-04-28 | 2012-11-01 | Tissuetech, Inc. | Methods of modulating bone remodeling |
| US9682044B2 (en) | 2011-06-10 | 2017-06-20 | Tissuetech, Inc. | Methods of processing fetal support tissues, fetal support tissue powder products, and uses thereof |
| WO2013061825A1 (en) | 2011-10-28 | 2013-05-02 | 凸版印刷株式会社 | Hollow needles manufacturing method and hollow needles |
| CA2795586A1 (en) | 2011-11-15 | 2013-05-15 | Golden Biotechnology Corporation | Methods and compositions for treatment, modification and management of bone cancer pain |
| US20130172424A1 (en) | 2011-12-30 | 2013-07-04 | Golden Biotechnology Corporation | Methods and compositions for treating diabetes |
| US8377946B1 (en) | 2011-12-30 | 2013-02-19 | Pharmacyclics, Inc. | Pyrazolo[3,4-d]pyrimidine and pyrrolo[2,3-d]pyrimidine compounds as kinase inhibitors |
| FR2987264A1 (en) | 2012-02-23 | 2013-08-30 | Golden Biotechnology Corp | METHODS AND COMPOSITIONS FOR THE TREATMENT OF CANCER METASTASES |
| KR102088651B1 (en) | 2012-02-29 | 2020-03-16 | 도판 인사츠 가부시키가이샤 | Needle-like material and method for manufacturing needle-like material |
| EP2636424A1 (en) | 2012-03-09 | 2013-09-11 | LTS LOHMANN Therapie-Systeme AG | Therapeutic system with hollow micro-needles |
| KR20150002685A (en) | 2012-03-26 | 2015-01-07 | 골든 바이오테크놀러지 코포레이션 | Methods and compositions for treating arteriosclerotic vascular diseases |
| KR102140553B1 (en) | 2012-06-22 | 2020-08-03 | 도판 인사츠 가부시키가이샤 | Needle-shaped body and manufacturing method for needle-shaped body |
| ES2846789T3 (en) | 2012-07-11 | 2021-07-29 | Tissuetech Inc | Compositions containing HC-HA / PTX3 complexes and methods of using them |
| WO2014059333A1 (en) | 2012-10-12 | 2014-04-17 | Calcimedica, Inc. | Compounds that modulate intracellular calcium |
| AU2013348248B2 (en) | 2012-11-21 | 2018-06-14 | Golden Biotechnology Corporation | Methods and compositions for treating neurodegenerative diseases |
| MX375307B (en) | 2012-12-21 | 2025-03-06 | Corium Inc | MICROARRAY FOR DELIVERY OF THERAPEUTIC AGENT AND METHODS OF USE. |
| TWI597061B (en) | 2013-02-20 | 2017-09-01 | 國鼎生物科技股份有限公司 | Methods and compositions for treating leukemia |
| CA3130120A1 (en) | 2013-03-12 | 2014-10-09 | Corium, Inc. | Microprojection applicators |
| EP2968475A2 (en) | 2013-03-14 | 2016-01-20 | Questcor Pharmaceuticals, Inc. | Acth for treatment of acute respiratory distress syndrome |
| JP2016514133A (en) | 2013-03-15 | 2016-05-19 | コリウム インターナショナル， インコーポレイテッド | MICROARRAY CONTAINING FINE STRUCTURE CONTAINING NO POLYMER, MANUFACTURING METHOD AND USE METHOD |
| AU2014233541B2 (en) | 2013-03-15 | 2018-11-22 | Corium Pharma Solutions, Inc. | Microarray for delivery of therapeutic agent, methods of use, and methods of making |
| AU2014233695A1 (en) | 2013-03-15 | 2015-10-01 | Corium International, Inc. | Microarray for delivery of therapeutic agent and methods of use |
| AU2014237357B2 (en) | 2013-03-15 | 2019-11-28 | Corium Pharma Solutions, Inc. | Multiple impact microprojection applicators and methods of use |
| EP2990072B1 (en) | 2013-04-26 | 2019-06-12 | Toppan Printing Co., Ltd. | Production method for acicular body |
| WO2014196522A1 (en) | 2013-06-03 | 2014-12-11 | 凸版印刷株式会社 | Needle body manufacturing method and manufacturing device |
| WO2014196562A1 (en) | 2013-06-06 | 2014-12-11 | 凸版印刷株式会社 | Needle body |
| KR101663450B1 (en) | 2013-07-22 | 2016-10-06 | 도판 인사츠 가부시키가이샤 | Needle-shaped body |
| WO2015017561A1 (en) | 2013-07-30 | 2015-02-05 | Zosano Pharma, Inc. | Low-profile microneedle patch applicator |
| WO2015054283A1 (en) | 2013-10-08 | 2015-04-16 | Calcimedica, Inc. | Compounds that modulate intracellular calcium |
| DE202013105133U1 (en)* | 2013-11-14 | 2015-02-18 | Holtsch Medizinprodukte Gmbh | Device for covering a puncture site |
| AU2014360446A1 (en) | 2013-12-05 | 2016-06-09 | Pharmacyclics, Llc | Inhibitors of Bruton's tyrosine kinase |
| AU2015213678C1 (en) | 2014-02-10 | 2019-03-21 | Respivant Sciences Gmbh | Mast cell stabilizers treatment for systemic disorders |
| JP2017505348A (en) | 2014-02-10 | 2017-02-16 | パタラ ファーマ リミテッド ライアビリティ カンパニー | Mast cell stabilizer for the treatment of lung diseases |
| WO2015164213A1 (en) | 2014-04-23 | 2015-10-29 | The Research Foundation For The State University Of New York | A rapid and efficient bioorthogonal ligation reaction and boron-containing heterocycles useful in conjuction therewith |
| TW201603818A (en) | 2014-06-03 | 2016-02-01 | 組織科技股份有限公司 | Compositions and methods |
| US10624843B2 (en) | 2014-09-04 | 2020-04-21 | Corium, Inc. | Microstructure array, methods of making, and methods of use |
| US9839644B2 (en) | 2014-09-09 | 2017-12-12 | ARKAY Therapeutics, LLC | Formulations and methods for treatment of metabolic syndrome |
| US9359316B1 (en) | 2014-11-25 | 2016-06-07 | Concentric Analgesics, Inc. | Prodrugs of phenolic TRPV1 agonists |
| US10227333B2 (en) | 2015-02-11 | 2019-03-12 | Curtana Pharmaceuticals, Inc. | Inhibition of OLIG2 activity |
| TW201642914A (en) | 2015-02-23 | 2016-12-16 | 組織科技股份有限公司 | Apparatuses and methods for treating ophthalmic diseases and disorders |
| BR112017018198A2 (en) | 2015-02-27 | 2018-04-10 | Curtana Pharmaceuticals Inc | inhibition of olig2 activity |
| CA2984443A1 (en) | 2015-05-20 | 2016-11-24 | Tissuetech, Inc. | Compositions and methods for preventing the proliferation and epithelial-mesenchymal transition of epithelial cells |
| US10857093B2 (en) | 2015-06-29 | 2020-12-08 | Corium, Inc. | Microarray for delivery of therapeutic agent, methods of use, and methods of making |
| WO2017027387A1 (en) | 2015-08-07 | 2017-02-16 | Patara Pharma, LLC | Methods for the treatment of mast cell related disorders with mast cell stabilizers |
| WO2017027402A1 (en) | 2015-08-07 | 2017-02-16 | Patara Pharma, LLC | Methods for the treatment of systemic disorders treatable with mast cell stabilizers, including mast cell related disorders |
| US20170209462A1 (en) | 2015-08-31 | 2017-07-27 | Pharmacyclics Llc | Btk inhibitor combinations for treating multiple myeloma |
| CN108601811A (en) | 2015-12-04 | 2018-09-28 | 得克萨斯州大学系统董事会 | SLC45A2 peptides for immunization therapy |
| TW201733600A (en) | 2016-01-29 | 2017-10-01 | 帝聖工業公司 | Fetal support tissue products and methods of use |
| WO2017147146A1 (en) | 2016-02-23 | 2017-08-31 | Concentric Analgesics, Inc. | Prodrugs of phenolic trpv1 agonists |
| EP3454945B1 (en) | 2016-05-12 | 2022-01-19 | The Regents Of The University Of Michigan | Ash1l inhibitors and methods of treatment therewith |
| CA3025268A1 (en) | 2016-05-25 | 2017-11-30 | Concentric Analgesics, Inc. | Prodrugs of phenolic trpv1 agonists in combination with local anesthetics and vasoconstrictors for improved local anesthesia |
| WO2017205762A1 (en) | 2016-05-27 | 2017-11-30 | Pharmacyclics Llc | Inhibitors of interleukin-1 receptor-associated kinase |
| WO2017205766A1 (en) | 2016-05-27 | 2017-11-30 | Pharmacyclics Llc | Inhibitors of interleukin-1 receptor-associated kinase |
| WO2017205769A1 (en) | 2016-05-27 | 2017-11-30 | Pharmacyclics Llc | Inhibitors of interleukin-1 receptor-associated kinase |
| AU2017314842B9 (en) | 2016-08-26 | 2022-02-10 | Curtana Pharmaceuticals, Inc. | Inhibition of Olig2 activity |
| CA3035528A1 (en) | 2016-08-31 | 2018-03-08 | Respivant Sciences Gmbh | Cromolyn compositions for treatment of chronic cough due to idiopathic pulmonary fibrosis |
| CN109803724A (en) | 2016-10-07 | 2019-05-24 | 瑞思皮万特科学有限责任公司 | For treating the Cromoglycic acid composition of pulmonary fibrosis |
| CA3082077A1 (en) | 2017-11-10 | 2019-05-16 | The Regents Of The University Of Michigan | Ash1l degraders and methods of treatment therewith |
| JP7414282B2 (en) | 2017-12-07 | 2024-01-16 | ザ リージェンツ オブ ザ ユニバーシティ オブ ミシガン | NSD family inhibitors and methods of treatment using them |
| US11685722B2 (en) | 2018-02-28 | 2023-06-27 | Curtana Pharmaceuticals, Inc. | Inhibition of Olig2 activity |
| WO2019236957A1 (en) | 2018-06-07 | 2019-12-12 | The Regents Of The University Of Michigan | Prc1 inhibitors and methods of treatment therewith |
| WO2020023794A1 (en) | 2018-07-27 | 2020-01-30 | Concentric Analgesics, Inc. | Pegylated prodrugs of phenolic trpv1 agonists |
| EP3906026A4 (en) | 2018-12-31 | 2022-10-19 | Biomea Fusion, LLC | IRREVERSIBLE MENIN-MLL INTERACTION INHIBITORS |
| JP7512248B2 (en)* | 2019-02-25 | 2024-07-08 | Ａｓｔｉ株式会社 | Needles and injection devices |
| SG11202109899VA (en) | 2019-03-15 | 2021-10-28 | Unicycive Therapeutics Inc | Nicorandil derivatives |
| CZ2019613A3 (en)* | 2019-10-02 | 2021-04-21 | Grade Medical s.r.o. | Equipment for the preparation of functionalized carriers for medical use |
| US20230190680A1 (en) | 2020-05-08 | 2023-06-22 | Golden Biotechnology Corporation | Methods and compositions for treating an rna virus induced disease |
| TW202208418A (en) | 2020-05-21 | 2022-03-01 | 美國德州系統大學評議委員會 | T cell receptors with vgll1 specificity and uses thereof |
| JP2023533982A (en) | 2020-07-10 | 2023-08-07 | ザ リージェンツ オブ ザ ユニバーシティ オブ ミシガン | GAS41 inhibitor and method of use thereof |
| CA3202151A1 (en) | 2020-12-16 | 2022-06-23 | Biomea Fusion, Inc. | Fused pyrimidine compounds as inhibitors of menin-mll interaction |
| CA3228627A1 (en) | 2021-08-11 | 2023-02-16 | Thomas Butler | Covalent inhibitors of menin-mll interaction for diabetes mellitus |
| WO2023027966A1 (en) | 2021-08-24 | 2023-03-02 | Biomea Fusion, Inc. | Pyrazine compounds as irreversible inhibitors of flt3 |
| US20240409558A1 (en) | 2021-09-13 | 2024-12-12 | Biomea Fusion, Inc. | Irreversible inhibitors of kras |
| US20250066386A1 (en) | 2021-11-09 | 2025-02-27 | Biomea Fusion, Inc. | Inhibitors of kras |
| WO2023119230A1 (en) | 2021-12-22 | 2023-06-29 | L'oreal | Coagulation pathway and nicotinamide-adenine dinucleotide pathway modulating compositions and methods of their use |
| JP2025502748A (en) | 2021-12-30 | 2025-01-28 | バイオメア フュージョン，インコーポレイテッド | Pyrazine Compounds as Inhibitors of FLT3 |
| WO2023235618A1 (en) | 2022-06-03 | 2023-12-07 | Biomea Fusion, Inc. | Fused pyrimidine compounds as inhibitors of menin |
| WO2024243402A2 (en) | 2023-05-24 | 2024-11-28 | Unicycive Therapeutics Inc. | Salt forms of nicorandil derivatives |
| WO2024249950A1 (en) | 2023-06-02 | 2024-12-05 | Biomea Fusion, Inc. | Fused pyrimidine compounds as inhibitors of menin |
| WO2025072556A1 (en) | 2023-09-26 | 2025-04-03 | Unicycive Therapeutics, Inc. | Amino acid prodrugs of nicorandil |