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DK0485563T3 - Polyether-substituted anti-tumor agents - Google Patents

Polyether-substituted anti-tumor agents

Info

Publication number
DK0485563T3
DK0485563T3DK91910296.2TDK91910296TDK0485563T3DK 0485563 T3DK0485563 T3DK 0485563T3DK 91910296 TDK91910296 TDK 91910296TDK 0485563 T3DK0485563 T3DK 0485563T3
Authority
DK
Denmark
Prior art keywords
substituted
polyether
amino group
tumor agents
polyethylene glycol
Prior art date
Application number
DK91910296.2T
Other languages
Danish (da)
Inventor
Hans-J Sinn
Hans-Hermann Schrenk
Wolfgang Maier-Borst
Eckhard Friedrich
Georgi Graschew
Dieter Woehrle
Thomas Klenner
Original Assignee
Deutsches Krebsforsch
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE4017439Aexternal-prioritypatent/DE4017439C2/en
Application filed by Deutsches KrebsforschfiledCriticalDeutsches Krebsforsch
Application grantedgrantedCritical
Publication of DK0485563T3publicationCriticalpatent/DK0485563T3/en

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Abstract

Substances for treating or diagnosing tumours, with preferred concentration in the tumor, are characterized in that they have at least two phenolic hydroxyl and/or amino groups, at least one aliphatic amino group, or at least one phenolic hydroxyl and/or amino group and at least one aliphatic amino group, and these groups are substituted with polyethylene glycol chains, whose degree of polymerization n is 5 to 250 and whose terminal hydroxyl group is substituted by C1?-C12? alkyl ester or ether, each substance being substituted by at least two such polyethylene glycol chains.
DK91910296.2T1990-05-301991-05-29 Polyether-substituted anti-tumor agentsDK0485563T3 (en)

Applications Claiming Priority (1)

Application NumberPriority DateFiling DateTitle
DE4017439ADE4017439C2 (en)1990-05-301990-05-30 Polyether-substituted tumor agents

Publications (1)

Publication NumberPublication Date
DK0485563T3true DK0485563T3 (en)1995-03-20

Family

ID=6407498

Family Applications (1)

Application NumberTitlePriority DateFiling Date
DK91910296.2TDK0485563T3 (en)1990-05-301991-05-29 Polyether-substituted anti-tumor agents

Country Status (7)

CountryLink
EP (1)EP0485563B1 (en)
JP (1)JP2640293B2 (en)
AT (1)ATE115864T1 (en)
DE (2)DE59103985D1 (en)
DK (1)DK0485563T3 (en)
ES (1)ES2068587T3 (en)
WO (1)WO1991018630A1 (en)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
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US5871710A (en)*1992-09-041999-02-16The General Hospital CorporationGraft co-polymer adducts of platinum (II) compounds
DE69332952T2 (en)*1992-09-042004-02-19The General Hospital Corp., Boston Biocompatible polymers containing diagnostic and therapeutic units
ES2140469T3 (en)*1992-10-142000-03-01Nycomed Imaging As COMPOSITIONS AND THERAPEUTIC AND DIAGNOSTIC METHODS FOR OBTAINING IMAGES.
US5817292A (en)*1992-10-141998-10-06Nycomed Imaging AsMR imaging compositions and methods
AU5323794A (en)*1992-10-141994-05-09Sterling Winthrop Inc.Chelating polymers
US5605672A (en)*1993-06-091997-02-25The General Hospital CorporationBlood pool imaging composition and method of its use
GB9408746D0 (en)*1994-05-031994-06-22Scotia Holdings PlcTumour locallising photosensitising compounds
US7255851B2 (en)1994-07-012007-08-14The Board Of Trustees Of The Leland Stanford Junior UniversityNon-invasive localization of a light-emitting conjugate in a mammal
TW319763B (en)1995-02-011997-11-11Epix Medical Inc
DE19514087A1 (en)*1995-04-131996-10-17Deutsches Krebsforsch Conjugate of an active ingredient, a polyether and possibly a native protein that is not considered foreign to the body
DE19706490C1 (en)*1997-02-191998-09-17Deutsches Krebsforsch Process for the preparation of acid amides and for the metallization of compounds and use of the compounds produced by the processes
WO1998048845A1 (en)*1997-04-291998-11-05Nycomed Imaging AsMethod of demarcating tissue
CA2341507C (en)1998-08-282011-05-24William Guy LovePorphyrin derivatives, their use in photodynamic therapy and medical devices containing them
GB0005855D0 (en)*2000-03-102000-05-03Scotia Holdings PlcCompounds for pdt
ITPD20030174A1 (en)*2003-07-312003-10-29Univ Padova POLYMERIC CONJUGATES FOR DIAGNOSTICS AND THERAPY
IL168184A (en)*2005-04-212011-11-30Univ Ariel Res & Dev Co LtdUse of a ligand-photosensitizer conjugate in combination with a chemiluminescent agent in the manufacture of a medicament for photodynamic therapy
WO2009058387A2 (en)2007-11-022009-05-07Nektar Therapeutics Al, CorporationOligomer-nitroimidazole anti-infective conjugates

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication numberPriority datePublication dateAssigneeTitle
US4824659A (en)*1985-06-071989-04-25Immunomedics, Inc.Antibody conjugates
DE3546150A1 (en)*1985-06-241987-01-22Hoechst Ag MEMBRANE ANCHOR ACTIVE CONJUGATE, ITS PRODUCTION AND USE
US4830847A (en)*1985-06-281989-05-16The Procter & Gamble CompanyDiphosphonate-derivatized macromolecules
IN165717B (en)*1986-08-071989-12-23Battelle Memorial Institute
CA1308377C (en)*1987-08-211992-10-06Henry Berger, Jr.Complex of polyethyleneglycol and tissue plasminogen activator
JPH0751592B2 (en)*1987-12-281995-06-05帝人株式会社 Cyclotriphosphazene derivative
DE3809671A1 (en)*1988-03-181989-09-28Schering Ag PORPHYRINE COMPLEX COMPOUNDS, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL AGENTS CONTAINING THEM
JPH0796558B2 (en)1988-03-311995-10-18協和醗酵工業株式会社 Modified polypeptide
WO1990015628A1 (en)1989-06-141990-12-27Cetus CorporationPolymer/antibiotic conjugate
DE4017439C2 (en)*1990-05-301994-06-23Deutsches Krebsforsch Polyether-substituted tumor agents

Also Published As

Publication numberPublication date
ES2068587T3 (en)1995-04-16
ATE115864T1 (en)1995-01-15
EP0485563A1 (en)1992-05-20
DE4139715A1 (en)1993-06-03
DE4139715C2 (en)1994-08-11
DE59103985D1 (en)1995-02-02
JP2640293B2 (en)1997-08-13
JPH05501885A (en)1993-04-08
EP0485563B1 (en)1994-12-21
WO1991018630A1 (en)1991-12-12

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