Clamp for fixing rabbits in pyrogen experimentTechnical Field
The application relates to the technical field of medical experiment instruments, in particular to a clamp for fixing rabbits in pyrogen experiments.
Background
Pyrogen refers to a heating substance which can cause abnormal rise of human body temperature after being injected into a body. Generalized pyrogens include bacterial pyrogens, endogenous high molecular pyrogens, endogenous low molecular pyrogens, chemical pyrogens, and the like.
The pyrogen reaction is characterized in that when intravenous drip and a large amount of transfusion are clinically carried out, cold fibrillation, high fever, sweating, fainting, vomiting and other symptoms can occur to a patient due to the fact that the liquid medicine contains pyrogens, and the rabbit is very sensitive to various viruses and pathogenic bacteria due to the fact that the rabbit is very sensitive to temperature changes, the pyrogen reaction can objectively reflect the heating condition of various medicines caused by the pyrogens in organisms, and a plurality of anti-infection medicines can be studied through the pre-infection of the rabbit, and then the temperature changes of animals can be monitored through a pyrogen meter probe.
The Chinese patent with publication number CN101984933A discloses an animal fixing device for experiments, which comprises a platform with supporting legs, wherein the platform is provided with holes penetrating up and down, the front surface of the platform is provided with a detachable hanging rod, the back surface of the platform is provided with a fixer for fixing animals, the position of the fixer corresponds to the holes, and the front surface of the platform is also provided with an elastic clamp.
According to the technology, in the process of measuring the body temperature change of the animal, the experimental animal is required to be fixed on the platform through the elastic clamp for experimental record, and the experimental animal is fixed on the platform for a long time, so that the experimental animal can generate stress reaction, the stress reaction can cause inaccurate body temperature detection result caused by pyrogen reaction of the experimental animal, and the defects exist.
Disclosure of utility model
In order to reduce the influence of stress reaction on the pyrogen reaction result of animals, the application provides a clip for fixing rabbits in pyrogen experiments.
The application provides a clip for fixing rabbits in a pyrogen experiment, which adopts the following technical scheme:
The clip comprises a clip body, wherein a fixing part and a clamping part are arranged on the clip body, the fixing part is used for fixing a pyrogen instrument probe, and the clamping part is used for clamping the tail of an experimental animal.
Through adopting above-mentioned technical scheme, the experimenter is fixed the pyrogen appearance probe on the checkpost body through the fixed part earlier, then fixes the checkpost body at the afterbody of experimental animal through the clamping part to realize the effect that the pyrogen appearance probe control experimental animal body temperature was changed constantly, and experimental animal is in the state of freely relaxing at the in-process that monitors body temperature and changes, more laminating experimental animal's normal living state, so that weaken experimental animal's experimental animal, thereby make experimental result more accurate.
Optionally, the cross section of checkpost body is U-shaped, fixed part including set up in the inboard separation arch of checkpost body, separate protruding with be provided with the friction layer on the inside wall of the U-shaped concave side of checkpost body, the friction layer is used for parcel pyrogen appearance probe.
Through adopting above-mentioned technical scheme, the checkpost body of U-shaped passes through the elasticity of its material, with pyrogen appearance probe card between separating protruding and the U-shaped concave side of checkpost body, the frictional force between pyrogen appearance probe and the checkpost body has been increased to the frictional layer simultaneously, has reduced the possibility that experimental animal in the motion process, the unexpected whereabouts of pyrogen appearance probe.
Optionally, a flexible layer is disposed on an inner side wall of the opening end of the clip body, and the flexible layer is located on a side of the separation protrusion opposite to the friction layer.
Through adopting above-mentioned technical scheme, when the checkpost body centre gripping at experimental animal afterbody, the flexible layer takes place extrusion deformation and laminating experimental animal's afterbody to this uncomfortable sense that weakens experimental animal afterbody and the stability of increase centre gripping, and then makes the checkpost body can firmly the centre gripping at experimental animal afterbody.
Optionally, the clamping part including set up in on the checkpost body and the transversal centre gripping piece that personally submits L shape, the inboard of centre gripping piece also is provided with the flexible layer, be provided with the coarse layer on the flexible layer, the coarse layer is used for contacting with the afterbody of experimental animal.
Through adopting above-mentioned technical scheme, the grip tab of L shape can provide fine parcel nature and stability to the afterbody of animal, can adapt to the afterbody of the experimental animal of equidimension not simultaneously, and the rough layer has increased the frictional force between checkpost body and the experimental animal simultaneously, makes the checkpost body can be better fix at the afterbody of experimental animal.
Optionally, the clamping part including rotate set up in grip block on the checkpost body, the inboard of grip block also is provided with the flexible layer, be provided with the delamination preventing on the flexible layer, the delamination preventing is used for contacting with the afterbody of experimental animal, the grip block with be provided with the torsional spring between the checkpost body.
Through adopting above-mentioned technical scheme, the experimenter rotates the grip block, and the torsional spring takes place to deform, then places the afterbody of experimental animal between grip block and checkpost body, and flexible layer takes place to deform and laminating experimental animal's afterbody, reduces simultaneously to the influence of pyrogen appearance probe fixed stability to the stability at experimental animal afterbody is fixed to the checkpost body is favorable to improving to the delamination.
Optionally, a pressing plate is arranged on the clamping plate, and an anti-slip strip is arranged on the pressing plate.
Through adopting above-mentioned technical scheme, the experimenter presses the clamp plate, and the clamp plate drives the grip block and rotates to this makes things convenient for experimenter to open the grip block, and the antislip strip has reduced the unexpected clamp plate that drops of experimenter's hand simultaneously and has led to the grip block to press from both sides the possibility of damaging experimental animal afterbody, is favorable to reducing experimental animal's stress.
Optionally, the cross section of grip block is L shape, the grip block is facing away from its rotation center's one end butt in on the checkpost body.
Through adopting above-mentioned technical scheme, reduced the afterbody of grip block excessive extrusion experimental animal, made experimental animal produce uncomfortable possibility, the grip block of L shape can provide fine parcel nature and stability to the afterbody of animal simultaneously.
Optionally, the clip body is located at the separation protrusion and is provided with a clamping groove, the clamping groove of the clip body is inserted with a clamping pin, and the cross section of the clamping pin is U-shaped.
Through adopting above-mentioned technical scheme, reduced because frequently using and led to the U-shaped concave side of checkpost body to take place plastic deformation, and then made the checkpost body to the possibility that pyrogen appearance probe centre gripping became invalid, be favorable to the stability of pyrogen appearance probe clamping state.
In summary, the present application includes at least one of the following beneficial technical effects:
1. The experiment personnel firstly fix the pyrogen instrument probe on the clamp body through the fixing part, and then fix the clamp body on the tail part of the experiment animal through the clamping part, so that the effect of monitoring the temperature change of the experiment animal by the pyrogen instrument probe at any time is realized, the experiment animal is in a free and relaxed state in the process of monitoring the temperature change, and the experiment animal is more attached to the normal living state of the experiment animal, so that the experiment animal of the experiment animal is weakened, and the experiment result is more accurate;
The U-shaped clamp body clamps the pyrogen meter probe between the separation bulge and the U-shaped concave side of the clamp body through the elasticity of the material of the U-shaped clamp body, and meanwhile, the friction layer increases the friction force between the pyrogen meter probe and the clamp body, so that the possibility that the pyrogen meter probe accidentally drops off in the movement process of experimental animals is reduced;
3. The experimenter rotates the grip block, and the torsional spring takes place to deform, then places the afterbody of experimental animal between grip block and checkpost body centre gripping, and flexible layer takes place to deform and laminating experimental animal's afterbody, reduces simultaneously to the influence of pyrogen appearance probe fixed stability to the delamination prevention is favorable to improving the stability of checkpost body fixed at experimental animal afterbody.
Drawings
Fig. 1 is a schematic structural view of embodiment 1 of the present application.
FIG. 2 is a schematic view showing the positional relationship of the holding plate, delamination preventing layer and pressing plate in example 2 of the present application.
FIG. 3 is a schematic view showing the positional relationship of the cleat, bayonet and pressure plate in embodiment 3 of the present application.
The reference numerals indicate that 1, a pyrogen meter probe, 2, a clip body, 3, a fixing part, 31, a separation protrusion, 32, a friction layer, 4, a clamping part, 41, a clamping piece, 42, a rough layer, 43, a clamping plate, 44, an anti-delamination layer, 45, a torsion spring, 5, a flexible layer, 6, a pressing plate, 7, an anti-slip strip, 8, a clamping groove, 9 and a clamping pin.
Detailed Description
The application is described in further detail below with reference to fig. 1-3.
The embodiment of the application discloses a clamp for fixing rabbits in a pyrogen experiment.
Example 1
Referring to fig. 1, a clip for fixing rabbits in pyrogen experiments includes a clip body 2 having a U-shaped cross section, the clip body 2 is made of plastic material, and has light weight, little uncomfortable feeling to the experimental animals, and is not easy to fall off, a fixing portion 3 and a clamping portion 4 are arranged on the clip body 2, the fixing portion 3 is used for fixing a pyrogen instrument probe 1, and the clamping portion 4 is used for clamping the tail of the experimental animals.
Referring to fig. 1, the fixing portion 3 includes two separation protrusions 31 integrally formed on the inner side of the U-shape of the clip body 2, a friction layer 32 is adhered to the inner side wall of the U-shape concave side of the separation protrusions 31 and the clip body 2, the cross section of the friction layer 32 is C-shaped, the friction layer 32 is used for wrapping the pyrogen meter probe 1, a flexible layer 5 is adhered to the inner side wall of the opening end of the clip body 2, the flexible layer 5 and the friction layer 32 are made of polyurethane rigid foam materials, and the polyurethane rigid foam can be compressed, and is convenient to clean and dry.
Referring to fig. 1, the flexible layer 5 is located at a side of the separation protrusion 31 facing away from the friction layer 32, the clamping portion 4 includes a clamping piece 41 integrally formed on the clip body 2 and having an L-shaped cross section, the clamping piece 41 abuts against the clip body 2, the flexible layer 5 is adhered to the inner side of the clamping piece 41, the rough layer 42 is adhered to the flexible layer 5, and the rough layer 42 is used for contacting with the tail of the experimental animal.
The embodiment 1 is implemented by the principle that an experimenter firstly breaks the U-shaped opening end of the clip body 2, the U-shaped concave side of the clip body 2 deforms, then the pyrogen meter probe 1 is placed on the U-shaped concave side of the clip body 2, then the U-shaped two ends of the clip body 2 are loosened, the U-shaped concave side of the clip body 2 recovers deformation, and the friction layer 32 is pressed on the pyrogen meter probe 1.
Then experimenter breaks the grip 41 off with fingers and thumb, then overlaps the U-shaped tip of checkpost body 2 at the afterbody of experimental animal, and here experimental animal can select the rabbit, then unclamp grip 41, flexible layer 5 is extruded in the afterbody of experimental animal and takes place deformation, flexible layer 5 takes place deformation and laminating experimental animal's afterbody, and rough layer 42 has increased the frictional force with experimental animal afterbody simultaneously to this makes checkpost body 2 by firm fixing at experimental animal's afterbody, so that reduces experimental animal's stress.
Example 2
Referring to fig. 2, the difference between this embodiment and embodiment 1 is that the clamping portion 4 includes a clamping plate 43 rotatably connected to the clip body 2 and having an L-shaped cross section, one end of the clamping plate 43 facing away from the rotation center abuts against the clip body 2, a flexible layer 5 is adhered to the inner side of the clamping plate 43, and an anti-delamination layer 44 is adhered to the flexible layer 5.
Referring to fig. 2, the anti-delamination layer 44 may be a double-sided tape, the anti-delamination layer 44 is used for adhering to the tail of an experimental animal, a torsion spring 45 is disposed at the rotation position between the clamping plate 43 and the clip body 2, the clamping plate 43 is integrally formed with the pressing plate 6, and the pressing plate 6 is integrally formed with the anti-slip strip 7.
The embodiment 2 is implemented by pressing the pressing plate 6 by an experimenter, the pressing plate 6 drives the clamping plate 43 to rotate around the axis of the pressing plate, the torsion spring 45 deforms, the experimenter can conveniently and rapidly fix the clip body 2 at the tail of the experimenter, and meanwhile, the anti-delamination layer 44 increases the adhesive force between the clip body 2 and the hair at the tail of the experimenter.
Example 3
Referring to fig. 3, the difference between this embodiment and embodiment 2 is that a clamping groove 8 is formed on the outer sidewall of the clip body 2 and located at the separation protrusion 31, and a clamping pin 9 with a U-shaped cross section is inserted into the clamping groove 8 of the clip body 2, and the clamping pin 9 is made of plastic material.
The embodiment 3 is implemented on the principle that the bayonet 9 can improve the stability of the clip body 2 to the clamping of the pyrogen meter probe 1 when the U-shaped concave side of the clip body 2 is plastically deformed due to frequent snapping.
The above embodiments are not intended to limit the scope of the application, so that the equivalent changes of the structure, shape and principle of the application are covered by the scope of the application.