CN221405728U - Sample analysis device - Google Patents

Abstract

The application provides a sample analysis device, which comprises a rack, a reagent bin module, a sample introduction module, a cup arranging module, an incubation module, a transfer module and a detection module, wherein the reagent bin module, the sample introduction module, the cup arranging module, the incubation module, the transfer module and the detection module are arranged on the rack; the cup arranging module is used for arranging the empty reaction cups and vertically downwards arranging the empty reaction cups to the discharging end in sequence; the incubation module is connected with the discharging end of the cup arranging module and is used for receiving and accommodating the empty reaction cups conveyed by the cup arranging module; the transfer module moves among the reagent bin module, the sample injection module and the incubation module, the transfer module is used for transferring the sample in the sample injection module and the reagent in the reagent bin module to the reaction cup in the incubation module, and the incubation module is used for uniformly mixing the reagent in the reaction cup and the sample for incubation reaction; the detection module is used for detecting the reagent for completing the incubation reaction in the incubation module. The application integrates a plurality of modules on the frame, can effectively save the layout space of the whole machine, and is beneficial to the miniaturization of equipment.

Description

Sample analysis device

Technical Field

The application belongs to the technical field of medical instruments, and particularly relates to a sample analysis device.

Background

The basic principle of immunodiagnosis is to use immunological technology, i.e. the specific combination of antigen and antibody to diagnose pathogen, and mainly covers the fields of virus and blood source inspection, hepatitis detection, venereal disease monitoring (HIV, etc.), tumor detection, etc. An automatic immunoassay device is a device for quantitatively analyzing a target analyte such as an antibody or an antigen contained in a test sample such as blood. In the working process, a detection sample and a reagent are generally added into a reaction cup, and after the steps of uniform mixing, incubation, cleaning and separation and the like, a marked signal reagent is added into the reaction cup to measure the marked signal so as to realize measurement and analysis of a target object contained in the detection sample. The part of immunity analyzer is provided with a cover opening and closing mechanism and comprises various mechanisms related to centrifugation, such as a reaction centrifugal cup accommodating mechanism, a reaction centrifugal cup conveying mechanism, a centrifugal mechanism and the like, the equipment components are more, and each module is loosely arranged, so that the volume is larger; in addition, the reaction cup of the partial immunity analyzer needs to be manually placed on the reaction cup placing frame in advance, and the transfer of the reaction cup is realized in a mechanical arm transfer mode. Therefore, development of an immunoassay analyzer is needed to solve the problems of large volume, complex structure, large occupied space and complex operation of the automatic immunoassay analyzer in the prior art.

Disclosure of utility model

The application mainly aims to provide a sample analysis device, which aims to solve the technical problems that the sample analysis device in the prior art is complex in structure and occupies large space.

In order to achieve the above object, the present application provides a sample analysis device, including a rack and a plurality of sample analysis devices disposed on the rack:

the reagent bin module is used for storing reagents required in the reaction process;

The sample injection module is used for storing a sample tube;

The cup arranging module is used for arranging the empty reaction cups and vertically downwards arranging the empty reaction cups to the discharging end in sequence;

The incubation module is connected with the discharging end of the cup arranging module and is used for receiving and accommodating the empty reaction cups conveyed by the cup arranging module;

The transfer module moves among the reagent bin module, the sample introduction module and the incubation module, and is used for transferring the sample in the sample introduction module and the reagent in the reagent bin module to the reaction cup in the incubation module, and the incubation module is used for uniformly mixing the reagent in the reaction cup and the sample for incubation reaction; and

And the detection module is used for detecting the reagent for completing the incubation reaction in the incubation module.

In one embodiment, the reagent cartridge module comprises a cartridge body, a mixing mechanism, a first refrigeration unit, a second refrigeration unit and a third driving mechanism; the mixing mechanism is arranged in the bin body and is used for mixing the samples; the first refrigerating unit and the second refrigerating unit are used for refrigerating the bin body and are arranged below the bin body at intervals in the transverse direction, and the first refrigerating unit and the second refrigerating unit are distributed in the longitudinal direction; the third driving mechanism is arranged between the first refrigerating unit and the second refrigerating unit and comprises a driving motor, a driving shaft and synchronous pulley assemblies distributed longitudinally, the top end of the driving shaft upwards penetrates through the bottom wall of the bin body and is connected with the mixing mechanism, the bottom end of the driving shaft is connected with the synchronous pulley assemblies, and the driving motor is vertically arranged and used for driving the synchronous pulley assemblies.

In one embodiment, the reagent cartridge module further comprises a sample tube and a reset assembly; the sample tube is detachably inserted on the mixing mechanism; the reset component is used for resetting the mixing mechanism and comprises a reset optocoupler sheet and a reset optocoupler; the reset optocoupler is arranged at the top or bottom of the driven wheel of the synchronous pulley assembly and is provided with a first detection part; the reset optocoupler is arranged on one side of the driven wheel, which is far away from the driving motor, and is used for detecting the first detection part; the position detection assembly is used for detecting the rotation position of the sample tube and comprises a position detection optical coupler sheet and a position detection optical coupler; the position detection optical coupling piece is arranged on the driven wheel and vertically spaced from the reset optical coupling piece, and a plurality of second detection parts which are distributed along the circumferential direction at intervals are formed on the position detection optical coupling piece; the position detection optocoupler and the reset optocoupler are vertically arranged at intervals and used for detecting the second detection part.

In an embodiment, the reagent cartridge module further comprises a first cold-blocking plate, a motor mount, an optocoupler mount, and a second cold-blocking plate; the first cold insulation plate is arranged at the bottom of the bin body; the motor mounting seat is arranged below the first cold insulation plate, a first mounting cavity is formed between the motor mounting seat and the first cold insulation plate, the driving wheel of the synchronous pulley assembly is mounted in the first mounting cavity along the horizontal direction, and the driving end of the driving motor upwards penetrates through the bottom wall of the motor mounting seat and is in driving connection with the driving wheel; the optical coupler installation seat is used for installing a reset optical coupler and a position detection optical coupler; the second cold-proof board sets up in the below of the storehouse body and is used for installing the opto-coupler mount pad.

In one embodiment, the sample injection module includes:

The mounting platform is provided with a sample conveying area and a cover opening area positioned at one lateral side of the sample conveying area;

A sample tray longitudinally movably provided at the sample conveying area and formed with a first conveying path for loading a sample rack;

the sampling track is transversely arranged in the uncovering area and can be communicated with the first conveying channel;

the first driving mechanism is arranged below the sampling track and is used for driving the sample rack on the sample tray to reciprocate to the first conveying channel and the sampling track;

the compressing mechanism is arranged in the uncapping area and positioned at one longitudinal side of the sampling track and is used for compressing the tube body of the sample tube;

And the cover opening mechanism is arranged in the cover opening area and is positioned on one side of the pressing mechanism away from the sampling track and is used for opening the tube cover of the sample tube.

In an embodiment, the number of the first conveying channels is multiple, and the sample injection module further comprises an induction device and a second driving mechanism; the sensing device is used for sensing the sample rack entering the first conveying channel; the second driving mechanism is used for driving the sample tray to move to the position where the first conveying channel is flush with the sampling track.

In an embodiment, the sample injection module further comprises a lifting mechanism and a connecting arm, wherein the lifting mechanism is arranged on the mounting platform in a lifting manner and is positioned at one side of the pressing mechanism away from the sample frame, and the connecting arm is arranged at the top of the lifting mechanism; the uncapping mechanism comprises an uncapping driving piece, a pivot shaft and two clamping pieces, wherein the pivot shaft is vertically arranged on the connecting arm, the clamping pieces comprise a connecting part and clamping parts, the upper ends of the clamping parts are connected with the connecting part and can clamp the tube cover of the sample tube from the upper end and the lower end, the connecting part is rotatably arranged on the pivot shaft along the horizontal direction, a clamping space for clamping the tube cover is formed between the two clamping parts, and the uncapping driving piece is arranged above the connecting arm along the horizontal direction and is used for driving the two clamping parts to be close to or far away from each other.

In one embodiment, the incubation module comprises an incubation plate, a stirring assembly, an optocoupler assembly, and a control unit; the incubation plate comprises a rotating plate and a reaction plate, a plurality of through holes for accommodating reaction cups are formed in the rotating plate along the circumferential direction, and reaction cup accommodating stations for inserting the bottoms of the reaction cups are formed in the reaction plate; the stirring component is arranged below the reaction disk and is used for stirring and uniformly mixing the reagent and the sample in the reaction cup; the second rotary driving assembly is used for driving the rotating disc to rotate; the optocoupler component is arranged on the reaction disc, acquires corresponding position information of the through hole and the reaction cup accommodating station and sends out a judging signal; the control unit is electrically connected with the optocoupler assembly and controls the second rotary driving assembly to act according to the received judging signal so that the through holes correspond to the reaction cup accommodating stations one by one.

In an embodiment, the rotating disc comprises a rotating ring coaxially arranged at intervals on the inner periphery of the reaction disc and a rotating cover plate covered on the rotating ring, a cover body is arranged on the rotating cover plate, and the incubation module further comprises:

A mounting table;

The cleaning and liquid injection assemblies are at least two groups and are arranged on the mounting table at intervals along the arc shape, the last cleaning and liquid injection assembly is used for sucking residual liquid in the reaction cup in the rotation direction of the rotating cover plate, and the rest cleaning and liquid injection assemblies are used for sucking the liquid in the reaction cup and injecting cleaning liquid;

and the lifting driving assembly is arranged on the cover body and used for driving the mounting table to lift.

In one embodiment, the cleaning and priming assembly includes:

The guide sleeve movably penetrates through the mounting table; and the reaction needle is integrated in the guide sleeve, and is used for sucking liquid in the reaction cup or injecting cleaning liquid into the reaction cup, the reaction needle at the tail position comprises a sucking needle for sucking liquid in the reaction cup, the rest reaction needles comprise a liquid injection needle for injecting the cleaning liquid into the reaction cup and a sucking needle for sucking the liquid in the reaction cup, and the plane of the bottom of the sucking needle is higher than that of the bottom of the liquid injection needle.

In one embodiment, an optocoupler assembly includes:

The plurality of position matching pieces are circumferentially arranged on the rotating disc and correspond to the reaction cup accommodating stations one by one;

The position optical coupler is matched with the position matching piece, acquires the position information of the reaction cup accommodating station, and sends out a judging signal according to the position information; and

The reset optocoupler is arranged on the reaction disc, a light blocking column is arranged on the rotating disc, and the reset optocoupler and the light blocking column are matched to detect whether the rotating disc reaches a reset initial position or not.

In one embodiment, the cup sorting module comprises a reaction cup charging bin, a cup sorting drum, a baffle, a first rotary driving assembly and a cup pushing mechanism; the reaction cup charging bin is used for containing reaction cups; the inner peripheral wall of the cup arranging rotary drum is provided with a plurality of partition sections at intervals, the partition sections are obliquely arranged relative to the inner peripheral wall of the cup arranging rotary drum, a guide channel is formed between any two adjacent partition sections, and the feeding end of the guide channel is communicated with the discharging end of the reaction cup charging bin; the baffle is positioned at one side of the cup arranging rotary drum, which is far away from the reaction cup charging bin, and a cup outlet for discharging the reaction cup is formed in the baffle; the first rotary driving assembly is used for driving the cup arranging rotary drum to rotate so as to drive the discharge end of each guide channel to sequentially rotate to a position communicated with the cup outlet; the cup pushing mechanism comprises a conveying assembly and a cup pushing assembly, the conveying assembly forms a cup falling opening and a second conveying channel communicated with the cup outlet, and the cup pushing assembly is used for sequentially pushing reaction cups in the second conveying channel to the cup falling opening; the cup pushing assembly comprises a pushing piece, a guide rail, a second linear driving piece and a first linear driving piece; the guide rail is arranged on the outer side wall of the conveying guide block along the first direction; the second linear driving piece is used for driving the pushing piece to approach or depart from the reaction cup in the cup falling channel along the second direction, and the first direction and the second direction are crossed; the first linear driving piece is arranged on the guide rail and used for driving the second linear driving piece to linearly move along the first direction.

In an embodiment, the sample analysis device further includes a cup-dropping module, where the cup-dropping module is used to grasp the liquid remaining in the reaction cup after the reaction in the incubation module is completed, and drop the discarded reaction cup to the waste recovery module;

The cup dropping module comprises a grabbing mechanism, a cup dropping pushing block, a lifting driving mechanism and a translation mechanism; the grabbing mechanism comprises an elastic clamping piece, a lifting plate and two clamping bodies which are in sliding connection with the lifting plate, wherein the two clamping bodies are oppositely arranged along a third direction and enclose a clamping groove; the cup-throwing push block is positioned between the two clamping bodies and is used for abutting the two clamping bodies, so that the two clamping bodies slide back to back along a third direction; the lifting driving mechanism is used for driving the lifting plate to reciprocate between a grabbing position and a cup throwing position along a fourth direction relative to the cup throwing pushing block; the reaction cup can extend into the clamping groove at the grabbing position and tension the elastic clamping piece, so that the elastic clamping piece applies elastic clamping force to the clamping body, the cup-losing push block can squeeze the clamping body at the cup-losing position, and the two clamping bodies can overcome the elastic clamping force in a third direction to slide oppositely and loosen the reaction cup; the translation mechanism is used for driving the lifting driving mechanism and the grabbing mechanism to synchronously translate along a third direction.

Through the technical scheme, the sample analysis device provided by the embodiment of the application has the following beneficial effects:

the sample analysis device integrates a plurality of modules on the rack, so that the layout space of the whole machine can be effectively saved, and the miniaturization of equipment is facilitated; the reagent bin module is used for storing reagents required in the reaction process; the sample injection module is used for storing a sample tube; the cup arranging module is used for arranging the empty reaction cups and vertically downwards arranging the empty reaction cups to the discharging end in sequence; the incubation module is connected with the discharging end of the cup arranging module and is used for receiving and accommodating the empty reaction cups conveyed by the cup arranging module; the transfer module moves among the reagent bin module, the sample injection module and the incubation module, the transfer module is used for transferring the sample in the sample injection module and the reagent in the reagent bin module to the reaction cup in the incubation module, and the incubation module is used for uniformly mixing the reagent in the reaction cup and the sample for incubation reaction; the detection module is used for detecting the reagent for completing incubation reaction in the incubation module, the whole detection process is simple to operate, the detection efficiency is improved, and the degree of automation is high.

Drawings

FIG. 1 is a schematic view of a sample analyzer according to an embodiment of the present application; FIG. 2 is a schematic view of the construction of a reagent cartridge module according to the present application in a first view; FIG. 3 is a schematic view of the construction of a reagent cartridge module according to the present application in a second view; FIG. 4 is a schematic view of the construction of a reagent cartridge module according to the present application in a third view; FIG. 5 is a schematic view of a first cross-sectional configuration of a reagent cartridge module according to the present application; FIG. 6 is a schematic view of a second cross-sectional configuration of a reagent cartridge module according to the present application; FIG. 7 is a schematic diagram of a sample injection module according to the present application at a first view angle; FIG. 8 is a schematic diagram of a sample injection module according to the present application at a second view angle; FIG. 9 is a schematic diagram of the overall structure of the lifting mechanism and the angle adjusting mechanism in the sample injection module according to the present application; FIG. 10 is a schematic diagram of a compacting mechanism in a sample injection module according to the present application; FIG. 11 is a schematic view of the structure of the cup management module according to the present application at a first view angle; FIG. 12 is a schematic view of the structure of the cup management module according to the present application at a second view angle; FIG. 13 is a schematic view of a partial structure of a cup tidying module according to the present application; FIG. 14 is a schematic view of the structure of an incubation module according to the application; FIG. 15 is a schematic view of an incubation module according to the application with the cover removed; FIG. 16 is a schematic view of the structure of the incubation module according to the application with the reaction tray removed; FIG. 17 is a schematic view of an incubation module according to the application with the rotating cover plate removed; FIG. 18 is a schematic view of the structure of a rotating cover plate in an incubation module according to the application; fig. 19 is a schematic structural view of a cup-dropping module according to the present application; fig. 20 is a schematic view of a partial structure of a cup-dropping module according to the present application; fig. 21 is a schematic view of a part of the structure of the grabbing mechanism in the cup dropping module according to the present application.

Description of the reference numerals

100. A reagent cartridge module; 1. a bin body; 2. a mixing mechanism; 201. a rotating disc; 2011. a fixed gear; 2031. a rotating gear, 2032, a rotating shaft; 20. a second cold-isolation plate; 3. a first refrigeration unit; 4. a second refrigeration unit; 501. a first driving motor; 503. a drive shaft; 502. a synchronous pulley assembly; 6. a semiconductor refrigeration sheet; 7. a heat dissipation block; 8. a heat radiation fan; 10. a support column; 13. a first cold-blocking plate; 14. a motor mounting seat; 15. a first mounting cavity; 1601. resetting the optocoupler; 1602. resetting the optocoupler; 17. a sample tube; 1801. position detection optocoupler; 1802. A position detection optocoupler; 19. an optical coupler mounting seat; 26. a bin temperature detector; 27. an in-bin temperature detector; 28. a temperature detector mount; 200. a sample injection module; 21. a mounting platform; 22. a sample delivery area; 23. a cover opening area; 202. a sample tray; 203. a sample rack; 204. sampling a track; 206. a compressing mechanism; 2061. a compression drive assembly; 2062. a pinch roller assembly; 2063. a compressing seat; 2064. a first guide rail; 2065. a first slider; 208. a cover opening mechanism; 2081. a cover opening driving member; 2082. a pivot shaft; 2083. A clamping member; 209. a conventional sample channel; 210. an emergency sample channel; 211. a conventional sample sensing piece; 212. an emergency sample sensing piece; 213. a second driving mechanism; 2131. a first transmission assembly; 2132. a threaded rod; 216. a second in-place detection baffle; 217. a second in-place detector; 220. a lifting mechanism; 221. a connecting arm; 222. a screw motor; 223. a first hooking portion; 224. an angle adjusting mechanism; 300. a cup arranging module; 301. a reaction cup charging bin; 302. a cup arranging rotary drum; 303. a guide channel; 304. a partition section; 305. A baffle; 306. a first rotary drive assembly; 307. a push cup assembly; 3071. a pushing member; 3072. a guide rail; 3073. a first linear driving member; 3074. a second linear driving member; 308. a cup outlet; 309. a second conveying path; 310. conveying guide blocks; 311. an inclined plate; 312. judging an optical coupler; 313. a cup falling channel; 314. a cup falling barrel; 315. a cup falling opening; 400. an incubation module; 401. a stirring assembly; 4011. a first rotary drive member; 4012. stirring the switching shaft; 4013. stirring and vibrating shafts; 402. a second rotary drive assembly; 403. A rotating disc; 4031. a rotating ring; 4032. rotating the cover plate; 404. a reaction plate; 405. a through hole; 406. a reaction cup receiving station; 407. a mounting table; 408. cleaning the liquid injection assembly; 4081. a suction needle; 4082. a liquid injection needle; 4083. a mounting block; 4084. a guide post; 4085. an elastic member; 409. a lifting driving assembly; 410. a reaction hole site; 411. a positional optocoupler; 412. resetting the optocoupler; 500. a transfer module; 600. a detection module; 700. a reaction cup; 800. a cup dropping module; 801. a grabbing mechanism; 8011. An elastic clamping member; 8012. a lifting plate; 8013. a clamping body; 8014. a first horizontal guide rail; 8015. wear-resistant sliding blocks; 8016. a second connecting plate; 8017. a roller; 8018. positioning columns; 802. a cup throwing pushing block is used; 803. a lifting driving mechanism; 804. a translation mechanism; 8041. a translation driving member; 8042. a transverse support plate; 8043. a tension adjustment assembly; 805. and (3) a bracket.

Detailed Description

As shown in fig. 1, the sample analysis device of the present application includes a rack, and a reagent cartridge module 100, a sample introduction module 200, a cup arranging module 300, an incubation module 400, a transfer module 500, and a detection module 600 which are disposed on the rack; the reagent cartridge module 100 is used for storing reagents required in the reaction process; the sample injection module 200 is used for storing the sample tube 17; the cup arranging module 300 is used for arranging the empty reaction cups 700 and vertically arranging the empty reaction cups 700 to the discharging end in sequence; the incubation module 400 is connected with the discharging end of the cup arranging module 300, and the incubation module 400 is used for receiving and accommodating the empty reaction cups 700 conveyed by the cup arranging module 300; the transfer module 500 moves among the reagent chamber module 100, the sample introduction module 200 and the incubation module 400, the transfer module 500 is used for transferring the sample in the sample introduction module 200 and the reagent in the reagent chamber module 100 to the reaction cup 700 in the incubation module 400, and the incubation module 400 is used for uniformly mixing the reagent in the reaction cup 700 and the sample for incubation reaction; the detection module 600 is used to detect reagents that complete the incubation reaction in the incubation module 400. The sample analysis device integrates a plurality of modules on the rack, can effectively save the layout space of the whole machine, is beneficial to the miniaturization of equipment, is simple to operate, improves the detection efficiency, and has high automation degree.

As shown in fig. 2 to 5, the reagent cartridge module 100 includes a cartridge body 1, a mixing mechanism 2, a first refrigerating unit 3 and a second refrigerating unit 4, and a third driving mechanism provided between the first refrigerating unit 3 and the second refrigerating unit 4; the mixing mechanism 2 is arranged in the bin body 1 and is used for mixing the reagent; the first refrigerating unit 3 and the second refrigerating unit 4 are used for refrigerating the bin body 1 and are arranged below the bin body 1 at intervals along the transverse direction, and the first refrigerating unit 3 and the second refrigerating unit 4 are distributed along the longitudinal direction; the third driving mechanism comprises a first driving motor 501, a driving shaft 503 and synchronous pulley assemblies 502 distributed along the longitudinal direction, the top end of the driving shaft 503 penetrates through the bottom wall of the bin body 1 upwards and is connected with the mixing mechanism 2, the bottom end of the driving shaft 503 is connected with the synchronous pulley assemblies 502, and the first driving motor 501 is arranged vertically and used for rotationally driving the synchronous pulley assemblies 502.

Specifically, the reacted reagent is stored in the bin body 1, and the first refrigeration unit 3 and the second refrigeration unit 4 refrigerate the bin body 1 to enable the interior of the bin body 1 to form a good refrigeration environment, so that the reagent is convenient to provide a good storage environment, and the reagent is ensured to have enough activity before being analyzed; when the first driving motor 501 rotates, power is sequentially transmitted to the synchronous pulley assembly 502 and the driving shaft 503, the driving shaft 503 drives the mixing mechanism 2 to move so as to mix the reagent, the mixing mechanism 2 can play a role in mixing the reagent during movement so as to further improve the accuracy of sample analysis, and the air in the bin body 1 can be disturbed, so that the temperature of each position in the bin body 1 is more uniform, and the storage environment of the sample is further improved.

That is, the reagent cartridge module 100 in this embodiment has a simple structure, and the layout of the first driving motor 501, the synchronous pulley assembly 502, the driving shaft 503, the first refrigerating unit 3 and the second refrigerating unit 4 makes more full use of the space below the cartridge body 1, has a compact layout, is beneficial to reducing the overall height of the reagent cartridge module 100, is beneficial to realizing a miniaturized design to reduce the occupied space, and has the advantages of low cost and convenient production and manufacture.

The synchronous pulley assembly 502 comprises a driving wheel, a driven wheel and a synchronous belt, the driving wheel is in driving connection with the driving end of the first driving motor 501, the driven wheel is longitudinally distributed at intervals with the driving wheel and is connected with the bottom end of the driving shaft 503, and the synchronous belt is sleeved on the outer sides of the driving wheel and the driven wheel.

In one embodiment of the present application, each of the first and second refrigerating units 3 and 4 includes a semiconductor refrigerating fin 6, a heat dissipating block 7, and a heat dissipating fan 8; the semiconductor refrigerating sheet 6 is arranged below the bin body 1; the heat dissipation block 7 is longitudinally arranged below the semiconductor refrigerating sheet 6 and is provided with a plurality of heat dissipation through grooves which are transversely distributed at intervals, and the heat dissipation through grooves are axially communicated; the heat radiation fan 8 is disposed immediately on one side in the longitudinal direction of the heat radiation through groove.

The semiconductor refrigerating sheet 6 comprises a heat absorption part and a heat dissipation part, the heat absorption part is arranged below the bin body 1 and is used for absorbing heat emitted by the bin body 1, and the heat dissipation part is arranged below the heat absorption part and is used for conducting heat emitted by the bin body 1. In the process of sample storage, the heat absorption part of the semiconductor refrigerating sheet 6 absorbs the heat of the bin body 1, so that the temperature in the bin body 1 is reduced, the heat absorption part transfers the absorbed heat to the heat dissipation part, and the heat dissipation part transfers the heat to the heat dissipation block 7; further, the heat dissipation block 7 comprises a plurality of heat dissipation fins which are transversely distributed at intervals, heat dissipation through grooves are formed between two adjacent heat dissipation fins, and the single heat dissipation fins on the heat dissipation block 7 are vertically distributed, so that the heat dissipation area is large, and the heat dissipation effect of the fins is improved; the two adjacent radiating fins transfer the heat to the air in the radiating through groove between the two radiating fins, and the air in the radiating through groove can be disturbed when the radiating fan 8 works, so that the air rapidly flows out of the radiating through groove and takes away the heat under the action of the radiating fan 8.

In one embodiment of the present application, the reagent cartridge module 100 further comprises three support columns 10 spaced below the cartridge body 1, wherein one support column 10 is located between the first refrigerating unit 3 and the second refrigerating unit 4 in the horizontal lateral direction, and the other two support columns 10 are located at two lateral sides of the first driving motor 501 and at one longitudinal end of the heat dissipating block 7 away from the first support column 10. Specifically, the above arrangement can avoid installation interference between the three support columns 10 and other parts below the bin body 1, and can also avoid the first support column 10 to shield the air inlet of the cooling fan 8 so as to influence the air inlet efficiency of the cooling fan 8, thereby avoiding reducing the cooling efficiency of the cooling block 7.

In one embodiment of the present application, the reagent cartridge module 100 further comprises a first cold barrier 13 disposed at the bottom of the cartridge body 1, and a motor mount 14 disposed below the first cold barrier 13; a first installation cavity 15 is formed between the motor installation seat 14 and the first cold insulation plate 13; the driving wheel of the synchronous pulley assembly 502 is installed in the first installation cavity 15 along the horizontal direction, and the driving end of the first driving motor 501 passes through the bottom wall of the motor installation seat 14 upwards and is in driving connection with the driving wheel. The above arrangement can prevent heat or cold energy transfer between the bin body 1 and the first driving motor 501, thereby avoiding temperature rise in the bin body 1, further improving refrigeration efficiency of the first refrigeration unit 3 and the second refrigeration unit 4, and avoiding the influence of the cold energy from the bin body 1 on the first driving motor 501 to reduce the service performance of the first driving motor 501.

Further, in this embodiment, the first cold-insulation plate 13 is made of polyoxymethylene material, and the first cold-insulation plate 13 made of polyoxymethylene material is beneficial to further improving difficulty in transferring heat or cold between the bin body 1 and the first driving motor 501.

In one embodiment of the present application, the reagent cartridge module 100 further comprises a reset component for resetting the mixing mechanism 2, the reset component comprising a reset optocoupler 1601 and a reset optocoupler 1602; the reset optocoupler 1601 is disposed on the top or bottom of the driven wheel of the synchronous pulley assembly 502 and forms a first detection portion; the reset optocoupler 1602 is disposed on a side of the driven wheel away from the first driving motor 501 and is used for detecting the first detecting portion.

Specifically, the reagent cartridge module 100 further includes a sample tube 17, the mixing mechanism 2 includes a sample tube mount, the sample tube 17 is detachably inserted on the sample tube mount, in this embodiment, the reset optocoupler 1601 is disposed at the bottom of the driven wheel, the first detection portion is a protruding baffle, the reset optocoupler 1601 rotates along with the driven wheel, and the reset optocoupler 1602 is disposed on the outer peripheral side of the reset optocoupler 1601 and is used for sensing the protruding baffle. Before the operator inserts the sample tube 17 on the sample tube mounting seat, the mixing mechanism 2 is reset through the reset assembly, and the sample tube mounting seat takes the position of the mixing mechanism 2 in the reset state as the zero position.

In one embodiment of the application, the reagent cartridge module 100 further comprises a sample tube 17 and a position detection assembly, the sample tube 17 being removably inserted on the mixing mechanism 2; the position detection assembly is used for detecting the rotation position of the sample tube 17 and comprises a position detection optical coupler 1801 and a position detection optical coupler 1802; the position detection optocoupler 1801 is arranged at the top of the driven wheel and vertically spaced from the reset optocoupler 1601, and a plurality of second detection parts distributed at intervals along the circumferential direction are formed on the position detection optocoupler 1801; the position detecting optocoupler 1802 and the reset optocoupler 1602 are vertically spaced apart and are configured to detect the second detecting portion. Specifically, the position detecting optocoupler 1801 also rotates along with the driven wheel, the second detecting portion is a notch formed on the position detecting optocoupler 1801, the position of the notch on the circumference corresponds to the position of the sample tube mounting seat on the circumference, and the position detecting optocoupler 1802 is disposed on the outer peripheral side of the position detecting optocoupler 1801 and is used for sensing the notch.

When the sample tubes 17 are inserted, the mixing mechanism 2 intermittently moves so as to rotate each sample tube mounting seat to a preset insertion position, and the relative angle between the preset insertion position and the zero position of each sample tube 17 can be determined through the position detection assembly; when the sample tube 17 at a certain circumferential position needs to be taken out, the mixing mechanism 2 is controlled to move according to the detection result of the position detection assembly, so that the sample tube mounting seat below the sample tube 17 to be taken out can be rotated to a preset inserting position, and the situation that the positions of the sample tube 17 are inconsistent in inserting and taking out due to the step loss phenomenon of the first driving motor 501 can be avoided.

Further, the first detecting portion of the reset optocoupler 1601 may be replaced by a notch provided on the protruding blocking piece, where the reset optocoupler 1602 senses the notch on the reset optocoupler 1601; the second detection portion of the position detection optocoupler 1801 may be replaced by a protruding baffle, where the positions of the protruding baffles on the position detection optocoupler 1801 and the positions of the sample tube mounting seats on the circumference correspond to each other one by one.

In one embodiment of the application, the reagent cartridge module 100 further comprises:

An optocoupler mounting base 19 for mounting the reset optocoupler 1602 and the position detection optocoupler 1802;

The second cold-insulating plate 20 is arranged below the bin body 1 and is used for installing the optocoupler installation seat 19.

The arrangement of the second cold-isolation plate 20 and the optocoupler mounting seat 19 can block heat or cold transfer between the bin body 1 and the reset optocoupler 1602 and between the second cold-isolation plate 20 and the position detection optocoupler 1802, so that temperature rise in the bin body 1 is avoided, the refrigeration efficiency of the first refrigeration unit 3 and the second refrigeration unit 4 is further improved, and the use performance of the reset optocoupler 1602 and the position detection optocoupler 1802 is reduced due to the influence of cold from the bin body 1.

Further, in this embodiment, the second cold-insulation plate 20 is made of polyoxymethylene, and the second cold-insulation plate 20 made of polyoxymethylene is beneficial to further improving the difficulty in transferring heat or cold between the bin body 1 and the reset optocoupler 1602 and the position detection optocoupler 1802.

As shown in fig. 6, the kneading mechanism 2 includes:

The rotary disk 201 is rotatably arranged in the bin body 1 along the horizontal direction, and through holes are formed in the rotary disk 201;

A fixed gear 2011 disposed below the rotating disk 201 in the horizontal direction;

The mixing module comprises a plurality of mixing components which are distributed along the radial direction of the rotating disc 201, each mixing component comprises a rotating gear 2031, a rotating shaft 2032 and a sample tube mounting seat, the rotating shaft 2032 is rotatably inserted into the through hole, the rotating gears 2031 are arranged at the bottom end of the rotating shaft 2032, two adjacent rotating gears 2031 are meshed with each other, the rotating gears 2031 at the innermost radial position are meshed with the fixed gears 2011, and the sample tube mounting seat is arranged at the top end of the rotating shaft 2032 and forms an insertion fit with the sample tube 17.

Specifically, in the process of storing samples, the sample tubes 17 are inserted into the sample tube mounting seat at the top end of the rotating shaft 2032 and move along with the rotating shaft 2032, the rotating disc 201 rotates under the driving action of the driving mechanism, the rotating disc 201 applies force to the rotating shaft 2032 through the peripheral wall of the through hole to drive the rotating gear 2031 in the mixing assembly adjacent to the fixed gear 2011 to rotate along the periphery of the fixed gear 2011, meanwhile, the rotating gear 2031 rotates due to meshing with the fixed gear 2011, and meanwhile, power is transmitted to the rotating gear 2031 adjacent to the rotating gear 2031 to drive the mixing assembly adjacent to the rotating gear 2031 to move, namely, each sample tube 17 and the samples inside revolve around the center of the circle of the rotating disc 201, and also rotate around the axis of the sample tube 17, so that mixing is achieved. The reagent cartridge module 100 in this embodiment has a simple structure, and the layout inside the cartridge body 1 is compact, so that the space utilization inside the cartridge body 1 and the storage and mixing efficiency of the reagent cartridge module 100 are improved, and the miniaturized design of the reagent cartridge module 100 is facilitated.

In one embodiment of the present application, the mixing mechanism 2 further includes a sample tube placing cylinder detachably provided on the rotating disk 201, the sample tube placing cylinder being sleeved outside the sample tube mounting seat and internally formed with a plurality of placing cavities for respectively accommodating the plurality of sample tubes 17 at the same circumferential position. Specifically, the radial outside in bottom of a sample tube placing barrel is equipped with the back-off, is equipped with first connecting plate on the rotary disk, is equipped with the back-off hole that is used for above-mentioned back-off card to go into on the first connecting plate, can realize through the cooperation between back-off and the back-off hole that sample tube placing barrel and rotary disk 201 can dismantle the connection to operating personnel place a sample tube placing barrel into the storehouse body 1 or take out from the storehouse body 1 according to actual demand.

In one embodiment of the application, the reagent cartridge module 100 further comprises a cartridge body temperature detector 26 for detecting the temperature of the cartridge body 1, an in-cartridge temperature detector 27 for detecting the temperature inside the cartridge body 1, and a temperature detector mount 28 provided on the circumferential wall of the cartridge body 1; the temperature detector mount 28 is formed with a second mounting chamber and a third mounting chamber for mounting the bin body temperature detector 26, the in-bin temperature detector 27, respectively.

The sample analysis device of the application further comprises an early warning module, the bin temperature detector 26 and the controller are all in communication connection, the bin temperature detector 26 sends the detection result to the controller, the controller compares the detection result with a pre-stored first preset temperature range, if the detection result is not in the first preset temperature range (such as 0-6 ℃), the semiconductor refrigerating sheet 6 is indicated to possibly fail, and the controller controls the early warning module to send an early warning signal so that a maintainer can check or maintain the semiconductor refrigerating sheet 6 as soon as possible. The in-bin temperature detector 27 sends the detection result to the controller, the controller compares the detection result with a pre-stored second preset temperature range (for example, 2-8 ℃), if the detection result is not in the second preset temperature range, it is indicated that the semiconductor refrigeration sheet 6 may malfunction, and at the moment, the controller controls the early warning module to send an early warning signal, so that a maintainer can check or maintain the semiconductor refrigeration sheet 6 as soon as possible.

As shown in fig. 7 to 10, the sample injection module 200 includes a mounting platform 21, a sample tray 202, a sampling track 204, a first driving mechanism, a pressing mechanism 206, and an uncapping mechanism 208; the mounting platform 21 is provided with a sample conveying area 22 and an uncovering area 23 positioned at one lateral side of the sample conveying area 22; the sample tray 202 is longitudinally movably provided at the sample conveying area 22 and forms a conveying passage for loading a sample rack 203 of the sample analysis device; the sampling rail 204 is disposed in the cover opening area 23 in the lateral direction and can communicate with the conveyance path; the first driving mechanism is arranged below the sampling track 204 and is used for driving the sample rack 203 to and from the conveying channel and the sampling track 204; a hold-down mechanism 206 is disposed on the open cover region 23 and located on one longitudinal side of the sampling track 204, for holding down the body of the sample tube 17 on the sample rack 203; the uncapping mechanism 208 is disposed in the uncapping area 23 on a side of the hold-down mechanism 206 remote from the sampling track 204.

Specifically, when a sample is required to be collected, an operator pushes the sample rack 203 loaded with the sample into the conveying channel, then controls the sample tray 202 to move longitudinally until the conveying channel loaded with the sample is flush with the sampling track 204, and then controls the first driving mechanism to drive the sample rack 203 into the sampling track 204 and move along the sampling track 204; further, a plurality of sample tubes 17 are arranged on the sample rack 203 at intervals along the transverse direction, the first driving mechanism intermittently moves each sample tube 17 onto the sampling track 204, so as to control the cover opening mechanism 208 to open the tube covers of each sample tube 17 one by one, and the transfer module 500 samples in each sample tube 17 one by one;

Further, before the uncapping operation is performed, the tube body of the sample tube 17 is compressed by the compressing mechanism 206, so that the tube cap is prevented from moving up and down in the uncapping process; after the pipe body is compressed, the cover opening mechanism 208 performs a cover opening operation so that the pipe cover gradually breaks away from the pipe body; after the uncapping operation is completed, the transfer module 500 of the sample analysis device can sample from the tube body so as to perform sample analysis; after the sampling operation is completed, the cap opening mechanism 208 can re-cap the tube cap onto the tube.

The sample injection module 200 in this embodiment includes the mounting platform 21 and all set up sample tray 202, sampling track 204, first actuating mechanism, hold-down mechanism 206 and uncapping mechanism 208 on the mounting platform 21, simple structure makes each part rationally distributed and compact under the condition that compromise the operation flow smoothness degree, has reduced the space requirement of sample injection module 200 in sample analysis device.

In one embodiment of the present utility model, the sample injection module further includes:

Sensing means for sensing the sample rack 203 entering the first transport path;

A second drive mechanism 213 for driving the sample tray 202 to a position where the first transport path is flush with the sampling track 204.

Specifically, the number of the first conveying channels and the number of the sensing devices are multiple, the sensing devices are arranged below the first conveying channels in a one-to-one correspondence manner, and each first conveying channel can convey conventional samples and emergency samples; the controller is in communication connection with the sensing device and the second driving mechanism 213, and can correspondingly control the first driving mechanism and the second driving mechanism 213 according to sensing signals of the sensing device; when a plurality of first conveying channels simultaneously convey the normal sample and the emergency sample, an operator inputs the serial numbers of the first conveying channels where the normal sample and the emergency sample are respectively located into a controller, then respectively places a sample rack 203 for loading the normal sample and a sample rack 203 for loading the emergency sample into the first conveying channels with the corresponding serial numbers, each sensing device senses that the sample rack 203 for loading the normal sample and the sample rack 203 for loading the emergency sample are placed, and then sends signals to the controller, and the controller controls the sample tray 202 to move after receiving the signals, and enables the first conveying channels where the emergency sample is located to be flush with the sampling track 204 so as to optimally complete emergency sample collection; after the emergency sample collection is completed, the first driving mechanism drives the sample rack 203 loaded with the emergency sample to retract into the first conveying channel, and the second driving mechanism 213 drives the sample tray 202 to move longitudinally until the first conveying channel loaded with the conventional sample is flush with the sampling track 204, so that the conventional sample collection is continuously completed.

In another embodiment of the present application, the plurality of first conveying channels includes a regular sample channel 209 and an emergency sample channel 210 arranged in parallel and spaced apart along a longitudinal direction, the sensing device includes a regular sample sensing element 211 and an emergency sample sensing element 212, the regular sample sensing element 211 is configured to sense the sample rack 203 entering the regular sample channel 209, and the emergency sample sensing element 212 is configured to sense the sample rack 203 entering the emergency sample channel 210; the second drive mechanism 213 is preferably responsive to the emergency sample sensor 212 and is used to drive the sample tray 202 to a position where the emergency sample channel 210 is flush with the sampling track 204.

Specifically, the conventional sample channel 209 and the emergency sample channel 210 are all penetrated in the lateral direction, the conventional sample sensor 211 is disposed at the inlet of the conventional sample channel 209, and the emergency sample sensor 212 is disposed at the inlet of the emergency sample channel 210.

When only the regular sample is needed to be sampled, an operator pushes the sample rack 203 loaded with the regular sample into the regular sample channel 209, the regular sample sensor 211 can sense the sample rack 203 loaded with the regular sample and send a corresponding sensing signal to the controller, the controller controls the second driving mechanism 213 to drive the sample tray 202 to move longitudinally after receiving the sensing signal until the regular sample channel 209 loaded with the regular sample is flush with the sampling track 204, and then controls the first driving mechanism to drive the sample rack 203 to move along the sampling track 204;

If the sample rack 203 loaded with the conventional sample is already arranged on the sampling track 204, and the tube covers of the sample tubes 17 on the sample rack 203 are all covered on the tube body, an operator pushes the sample rack 203 loaded with the emergency sample into the emergency sample channel 210, the emergency sample sensing piece 212 can sense the sample rack 203 loaded with the emergency sample and send a corresponding sensing signal to the controller, the controller firstly controls the first driving mechanism to retract the sample rack 203 loaded with the conventional sample back into the conventional sample channel 209 after receiving the sensing signal, then controls the second driving mechanism 213 to drive the sample tray 202 to move longitudinally until the emergency sample channel 210 loaded with the emergency sample is flush with the sampling track 204, and then drives the sample rack 203 loaded with the emergency sample to move along the sampling track 204 through the first driving mechanism so as to preferably complete the emergency sample collection; after the emergency sample collection is completed, the first driving mechanism drives the sample rack 203 loaded with the emergency sample to retract into the emergency sample channel 210, and the second driving mechanism 213 drives the sample tray 202 to move longitudinally until the conventional sample channel 209 loaded with the conventional sample is flush with the sampling track 204, so that the conventional sample collection is continued to be completed.

Further, if the sample rack 203 loaded with the normal samples is already present on the sampling track 204, but when the tube cover of the sample tube 17 on the sample rack 203 is opened, the operator pushes the sample rack 203 loaded with the emergency samples into the emergency sample channel 210, the emergency sample sensor 212 can sense the sample rack 203 loaded with the emergency samples and send a corresponding sensing signal to the controller, and the controller controls the cover opening mechanism 208 and the transfer module 500 to continuously complete the cover opening operation and the sampling operation corresponding to the sample tube 17 with the opened tube cover after receiving the sensing signal, so that the cover opening mechanism 208 and the transfer module 500 can be prevented from performing the secondary cover opening operation and the sampling operation on the sample tube 17 in the subsequent normal sample collection process, and sample pollution caused by the fact that the sample tube 17 is in the opened state for many times can be avoided; after the cover opening operation and the sampling operation corresponding to the sample tube 17 are completed, the controller controls the first driving mechanism to retract the sample rack 203 loaded with the conventional sample into the conventional sample channel 209, then controls the second driving mechanism 213 to drive the sample tray 202 to move longitudinally until the emergency sample channel 210 loaded with the emergency sample is flush with the sampling track 204, and then controls the first driving mechanism to drive the sample rack 203 loaded with the emergency sample into the sampling track 204 and move along the sampling track 204, so as to preferably complete the emergency sample collection; after the emergency sample collection is completed, the first driving mechanism drives the sample rack 203 loaded with the emergency sample to retract into the emergency sample channel 210, and the second driving mechanism 213 drives the sample tray 202 to move longitudinally until the conventional sample channel 209 loaded with the conventional sample is flush with the sampling track 204, so that the conventional sample collection is continued to be completed. Compared with the prior art, the sample injection module 200 integrates conventional sample injection and emergency sample injection without additionally increasing the overall occupied space, thereby being beneficial to carrying out preferential sample injection acquisition processing on emergency samples.

Specifically, the conventional sample sensor 211 further includes a first motion reed disposed below the first sensor and connected to the first sensor, and the emergency sample sensor 212 further includes a second motion reed disposed below the second sensor and connected to the first sensor, where the first sensor and the second sensor may be light-sensitive sensors.

In one embodiment of the present application, a first hooking portion 223 is formed at one end of the sample holder 203, and a bar-shaped hole distributed in a lateral direction is formed on the sampling rail 204, and the first driving mechanism includes:

the screw motor 222 is transversely arranged below the sampling track 204;

The first connecting block is arranged on the screw rod part of the screw rod motor 222 and is in threaded connection with the screw rod part;

The handle is arranged on the screw rod part and connected with the first connecting block, and a second hooking part which penetrates out of the strip-shaped hole upwards and is used for hooking the first hooking part 223 is formed on the handle.

Specifically, the first hooking portion 223 is disposed at the lower end of the side end surface of the sample rack 203, and when the operator pushes the sample rack 203 into the normal sample channel 209 or the emergency sample channel 210, the first hooking portion 223 is at one end of the sample rack 203 near the sampling track 204, and the second hooking portion can hook the first hooking portion 223 subsequently; the sampling track 204 is vertically arranged above the mounting platform 21 at intervals, the lead screw motor 222 is in communication connection with the controller, the lead screw motor 222 is arranged below the sampling track 204 and at one end of the sampling track 204 far away from the sampling area, when the lead screw motor 222 rotates forwards, the first connecting block drives the handle to move along the axial direction of the lead screw part, when the first connecting block moves to a first preset position, the second hooking part on the handle can hook the first hooking part 223 of the sample rack 203, then the lead screw motor 222 is controlled to rotate reversely, the first connecting block moves reversely along the lead screw part along the handle, and meanwhile, the second hooking part can pull the sample rack 203 to enter the sampling track 204 from a normal sample track or an emergency sample track and move along the sampling track 204; after the sample collection is completed, the screw motor 222 is controlled to rotate forward, the first connecting block moves along the screw rod portion towards the direction of the sample injection area along with the handle, and meanwhile, the second hooking portion can push the sample rack 203 to return to the normal sample track or the emergency sample track from the sampling track 204.

In one embodiment of the present application, the sample injection module 200 further includes a first in-place detection flap and a first in-place detector; the first in-place detection baffle is connected with the first connecting block; the first in-place detector is disposed below the sampling track 204 and is used to detect in-place of the first in-place detection flap. Specifically, the first in-place detection baffle plate can be an optical coupling plate, and the first in-place detector is in communication connection with the controller and can be an optical coupling detector.

In one embodiment of the present application, the second drive mechanism 213 includes a second drive motor, a first transmission assembly 2131, a threaded rod 2132, and a third connection block; the second driving motor is longitudinally arranged in the cover opening area 23; the first transmission end of the first transmission assembly 2131 is in driving connection with a second drive motor; the threaded rod 2132 is longitudinally disposed in the sample delivery area 22 and is connected to the second drive end of the first drive assembly 2131; the third connection block is movably disposed on the threaded rod 2132 and connected with the sample tray 202. Specifically, the first transmission assembly 2131 includes a first driving wheel, a first driven wheel and a first driving belt, the first driving wheel is connected with a second driving motor, the first driven wheel is connected with a threaded rod 2132, the first driving belt is sleeved on the outer sides of the first driving wheel and the first driven wheel, the second driving motor rotates to sequentially drive the first transmission assembly 2131 and the threaded rod 2132 to rotate, and the third connecting block can move along the axial direction of the threaded rod 2132, so that the adjustment of the longitudinal position of the sample tray 202 is realized.

In one embodiment of the present application, the sample injection module 200 further includes a second in-place detection flap 216 and a second in-place detector 217; the second in-place detection flap 216 is connected to the sample tray 202; the second in-position detector 217 is provided on the mounting platform 21 and is used for in-position detection of the second in-position detection flap 216.

Specifically, the second in-place detecting tab 216 may be an optocoupler, the second in-place detector 217 is communicatively connected to the controller and may be an optocoupler detector, the second in-place detecting tab 216 moves longitudinally with the sample tray 202 when the second driving motor of the second driving mechanism 213 rotates, and the second in-place detector 217 detects the second in-place detecting tab 216 when the sample tray 202 moves to a second preset position, which may be set as a position origin of the sample tray 202, and the second in-place detecting tab 216, the second in-place detector 217 and the second driving motor cooperate so that the controller determines and adjusts the position of the sample tray 202 in the longitudinal direction.

In one embodiment of the present application, the pressing mechanism 206 includes a pressing driving assembly 2061, a pressing wheel assembly 2062 and a pressing seat 2063, the pressing driving assembly 2061 is vertically disposed on the mounting platform 21 of the cover opening area 23, the pressing wheel assembly 2062 is disposed on the pressing driving assembly 2061 and can vertically ascend and descend, a vertical groove facing the pressing mechanism 206 is formed on the sample holder 203, the pressing seat 2063 is rotatably disposed on the pressing driving assembly 2061 and is used for pressing a tube body through the vertical groove, and a guiding inclined surface which gradually inclines from bottom to top toward the pressing wheel assembly 2062 and is used for guiding the pressing wheel of the pressing wheel assembly 2062 is formed on a side wall of the pressing seat 2063 far from the sample holder 203.

Specifically, the compression driving assembly 2061 includes a compression mount disposed on the mounting platform 21 and a compression driver disposed below the mounting platform 21 and having a drive shaft 503 passing upwardly through the mounting platform 21 and the compression mount in sequence, in this embodiment, the compression driver may be a through shaft motor; pinch roller assembly 2062 includes a first rail 2064, a first slider 2065, and a pinch roller, wherein first rail 2064 is vertically disposed on a pinch mount; the first sliding block 2065 is arranged on the first guide rail 2064 and is in driving connection with the compression driving piece, a transversely protruding pinch roller mounting part is also formed on the first sliding block 2065, and a screw rod of a through shaft motor passes through the mounting platform 21 upwards and compresses the bottom wall of the mounting seat and is in threaded connection with the first sliding block 2065; the pinch roller is rotatably provided on the pinch roller mounting portion and can roll up and down along a guide slope on the pinch roller holder 2063.

Before the body of the sample tube 17 is not compressed, the first sliding block 2065 is at the second preset height, the pressing wheel is at the bottom end of the guiding inclined plane, and the compressing seat 2063 does not apply compressing force to the body; when the tube body of the sample tube 17 needs to be compressed, the through shaft motor rotates and drives the first sliding block 2065 to move upwards along the first guide rail 2064, the pressing wheel moves upwards along the guide inclined plane, pressure is gradually applied to the compressing seat 2063 in the process of moving upwards, the compressing seat 2063 deflects towards the direction of the sample tube 17, further, the top end of the compressing seat 2063 gradually applies compressing force to the tube body, when the first sliding block 2065 rises to a third preset height, the compressing seat 2063 completely compresses the tube body, the tube body is prevented from moving upwards along with the first sliding block 2065 when the cover opening mechanism 208 applies upward force to the tube cover, the reliability of cover opening operation is ensured, and a plurality of parts in the compressing mechanism 206 are vertically distributed, so that the compressing mechanism has the advantages of compact structure and small occupied space.

In one embodiment of the present application, the sample injection module 200 further includes a third in-place detection flap coupled to the compression mount 2063 and a third in-place detector disposed on the compression mount; the third in-place detector is used for in-place detection of the third in-place detection baffle.

Specifically, the third in-place detection blocking piece may be an optical coupler, and the third in-place detector is communicatively connected to the controller and may be an optical coupler detector, and when the pressing seat 2063 is not deflected, the third in-place detector detects the third in-place detection blocking piece, and the position may be set as the position origin of the pressing seat 2063; when the pressing seat 2063 deflects, the third in-place detecting blocking piece deflects along with the pressing seat 2063, and when the pressing seat 2063 deflects in place, the third in-place detecting blocking piece cannot be detected by the third in-place detector, which indicates that the pressing seat 2063 has pressed the pipe body, and the cooperation of the third in-place detecting blocking piece and the third in-place detector is convenient for the controller to determine whether the pipe body is in a pressed state.

In one embodiment of the present application, as shown in fig. 9, the sample injection module 200 further includes a lifting mechanism 220 and a connecting arm 221, wherein the lifting mechanism 220 is disposed on the mounting platform 21 in a lifting manner and is located at a side of the pressing mechanism 206 away from the sample rack 203, and the connecting arm 221 is disposed at the top of the lifting mechanism 220; the cover opening mechanism 208 comprises a cover opening driving member 2081, a pivot shaft 2082 and two clamping members 2083, wherein the pivot shaft 2082 is vertically arranged on the connecting arm 221, the two clamping members 2083 comprise a connecting portion and a clamping portion, the upper ends of the clamping portions are connected with the connecting portion and can clamp the tube cover of the sample tube 17 from the upper end and the lower end, the connecting portion can be rotationally arranged on the pivot shaft 2082 along the horizontal direction, a clamping space for clamping the tube cover is formed between the clamping portions of the two clamping members 2083, and the cover opening driving member 2081 is arranged above the connecting arm 221 along the horizontal direction and is used for driving the clamping portions of the two clamping members 2083 to be close to or far away from each other.

Before the uncapping operation is performed, the body of the sample tube 17 is compressed by the compressing mechanism 206, the two clamping pieces 2083 are in an open state, the tube cover is in the clamping space, and the lifting mechanism 220 is at a first preset height, so that the upper clamping part and the lower clamping part can be used for clamping the top surface and the bottom surface of the tube cover respectively; when the uncapping operation is performed, the uncapping driver 2081 drives the connection parts of the two clamping pieces 2083 to rotate around the pivot shaft 2082 and the angle between the connection parts is gradually reduced, the clamping parts of the two clamping pieces 2083 are close to each other until the clamping parts of the two clamping pieces 2083 can clamp the pipe cover from the circumferential direction, then the uncapping driver 2081 stops driving and the lifting mechanism 220 performs the lifting operation, and the lower clamping part applies upward acting force to the bottom surface of the pipe cover so that the pipe cover is gradually separated from the pipe body to complete the uncapping operation; after the sampling operation is completed, the cover opening mechanism 208 may perform a cover opening operation, that is, the lifting mechanism 220 descends to enable the pipe cover to be covered on the pipe body again, and after the inner peripheral wall of the pipe cover contacts with the outer peripheral wall of the pipe body, the upper clamping portion applies a downward acting force to the top surface of the pipe cover, so that the pipe cover continues to descend to be covered on the pipe body completely.

In one embodiment of the present application, the connecting portions of the two clamping members 2083 are respectively provided with a first chute and a second chute, the first chute and the second chute are in outward expansion distribution, the cover opening mechanism 208 further includes a second connecting block in driving connection with the telescopic end of the cover opening driving member 2081, and a first connecting column and a second connecting column for respectively inserting into the first chute and the second chute are formed at the bottom of the second connecting block.

Specifically, the cover opening driving member 2081 in this embodiment is a telescopic motor, when the telescopic end of the telescopic motor extends, the second connecting block is driven to move in a direction away from the telescopic motor, the first connecting column and the second connecting column move from the first end (i.e. the end close to the telescopic motor) to the second end (i.e. the end far away from the telescopic motor) of the first chute and the second chute, and the connecting portions of the two clamping members 2083 are driven to rotate around the pivot shaft 2082, and the two clamping portions respectively connected with the two connecting portions are made to approach each other, so that the two clamping members 2083 clamp the pipe cover; conversely, the two clamping portions respectively connected to the two connecting portions may be separated from each other, so that the two clamping members 2083 release the tube cover.

As shown in fig. 11 to 13, the cup sorting module 300 of the present application includes a cuvette loading bin 301 for accommodating a plurality of cuvettes 700, a cup sorting drum 302, a baffle 305, a first rotary driving assembly 306, and a cup pushing mechanism; a plurality of partition sections 304 are arranged on the inner peripheral wall of the cup arranging rotary drum 302 at intervals, the partition sections 304 are obliquely arranged relative to the inner peripheral wall of the cup arranging rotary drum 302, a guide channel 303 is formed between any two adjacent partition sections 304, and the feeding end of the guide channel 303 is communicated with the discharging end of the reaction cup charging bin 301; the baffle 305 is positioned at one side of the cup arranging rotary drum 302, which is away from the reaction cup loading bin 301, and a cup outlet 308 for discharging the reaction cup 700 is formed in the baffle 305; the first rotary driving assembly 306 is used for driving the cup arranging drum 302 to rotate so as to drive the discharge end of each guide channel 303 to rotate to a position communicated with the cup outlet 308 in sequence; the cup pushing mechanism comprises a conveying assembly and a cup pushing assembly 307, the conveying assembly forms a cup falling opening 315 and a second conveying channel 309 communicated with the cup outlet 308, and the cup pushing assembly 307 is used for sequentially pushing the reaction cups 700 in the second conveying channel 309 to the cup falling opening 315. When the cup sorting operation is performed, a plurality of reaction cups 700 in the reaction cup storage bin 301 enter the cup sorting drum 302, the first rotary driving assembly 306 drives the cup sorting drum 302 to rotate, so that under the action of centrifugal force of rotation, the reaction cups 700 flow into each guide channel 303, and along with the rotation, when any one guide channel 303 is aligned with the cup outlet 308, as the extension lines of the side walls of the opposite faces of the two partition sections 304 and the extension lines of the inner peripheral wall of the cup sorting drum 302 are arranged in a crossing way towards the direction of the cup outlet 308, the reaction cups 700 in the guide channels 303 are thrown out from the cup outlet 308 and enter the second conveying channel 309; the reaction cup 700 falls vertically under the action of gravity, and then the cup pushing assembly 307 pushes the reaction cup 700 in the second conveying passage 309 to the cup falling opening 315 to fall into the reaction disk 404 to start the next process. The cup arranging rotary drum 302 is improved in the inner peripheral wall structure, and the cup falling and pushing functions of the second conveying channel 309 and the cup pushing component 307 are matched, so that the disordered reaction cups 700 can vertically fall into the second conveying channel 309 in sequence under the combined action of the first rotary driving component 306 and gravity, and the cup clamping condition can not occur.

In one embodiment, the plurality of guide channels 303 are arranged in sequence along the circumference of the cup managing drum 302, and the opposite surfaces of the two partition sections 304 forming the same guide channel 303 are arranged in a relatively inclined manner with respect to the inner circumferential wall of the cup managing drum 302. According to the application, through improving the angle of the inner peripheral wall of the guide channel 303, the inner side walls of the two partition sections 304 can prevent the reaction cups 700 in the guide channels 303 from flying out, so that the reaction cups 700 in each guide channel 303 are always kept in the guide channels until the discharge end of the guide channel 303 is communicated with the cup outlet 308, and the reaction cups 700 in the guide channels 303 communicated with the cup outlet 308 are driven to be thrown out from the cup outlet 308.

In one embodiment, the second conveying channel 309 includes a vertical channel, a V-shaped channel and a cup falling channel 313 that are sequentially communicated from top to bottom, the large end of the V-shaped channel is opened towards the vertical channel, the small end of the V-shaped channel is communicated with the cup falling channel 313, and one end of the cup falling channel 313 is communicated with the cup falling opening 315. The cup falling channel 313 is a long strip guide hole which is vertically communicated, the upper end of the cup falling channel 313 is communicated with the V-shaped groove channel, the lower end of the cup falling channel 313 is an opening, so that the reaction cup 700 falling into the cup falling channel 313 can vertically fall into the cup falling channel 313 under the action of gravity, and the bottom of the reaction cup 700 can extend out from the bottom of the cup falling channel 313. Because the peripheral wall of the reaction cup 700 is provided with a circle of clamping ring, the clamping ring can be clamped at the top end of the cup falling channel 313 in the falling process of the reaction cup 700, so that the whole reaction cup 700 is prevented from sliding from the bottom of the cup falling channel 313. In addition, with falling the setting of cup passageway 313 along the extension of fore-and-aft direction, the reaction cup 700 that drops like this can be in pushing away the promotion of cup subassembly 307 down towards falling the rim of a cup 315 and remove, and a plurality of reaction cups 700 that do not fall from falling the rim of a cup 315 are arranged in proper order around along the extending direction of falling the cup passageway 313, prevent that reaction cup 700 from appearing horizontal cup phenomenon to guarantee that every reaction cup 700 can pass through smoothly in proper order from falling the rim of a cup 315, and then avoid appearing card cup or the disorder condition.

In an embodiment, the cup arranging module 300 further comprises a baffle 305, the baffle 305 is sealed at one side of the cup arranging drum 302 away from the reaction cup charging bin 301, a cup outlet 308 is formed on the baffle 305, and the cup outlet 308 is provided with an inclined guide plate extending into the vertical channel. Preferably, the inclination angle of the inclined guide plate is set to 45 °, and by this design, the reaction cups 700 slid out of the cup outlet 308 can be sequentially dropped into the vertical channel at an inclination angle of 45 ° by the inclined guide of the inclined guide plate.

In one embodiment, the transport assembly includes a transport guide block 310 and two inclined plates 311; a cup falling channel 313 for the reaction cups 700 to be sequentially arranged is formed in the conveying guide block 310 along the first direction, a cup falling barrel 314 communicated with the cup falling channel 313 is formed below the end part of the conveying guide block 310, and a cup falling opening 315 is formed in the bottom of the cup falling barrel 314;

two inclined plates 311 are mounted on the conveying guide block 310 and symmetrically arranged on two sides of the top of the cup falling channel 313, and a V-shaped groove channel communicated with the cup falling channel 313 is formed between the two inclined plates 311. The reaction cup 700 falling into the vertical channel from the cup outlet 308 at an inclined angle of 45 degrees gradually becomes a vertical falling motion under the action of gravity; in order to enable the reaction cup 700 to fall into the cup falling channel 313 in a vertical posture, a V-shaped groove channel with guiding functions on two sides is arranged between the cup falling channel 313 and the vertical channel, so that all the reaction cups 700 can fall vertically.

In order to prevent the reaction cup 700 in the cup falling passage 313 from falling, but the reaction cup 700 pushed into the cup falling barrel 314 is to fall from the cup falling opening 315 at the bottom, the inner diameter of the cup falling barrel 314 needs to be designed to be larger than the width of the cup falling passage 313, so that the reaction cup 700 pushed from the cup falling passage 313 can smoothly fall from the cup falling opening 315 of the cup falling barrel 314. In addition, in order to ensure the orderly proceeding of the falling cups, the inner diameter of the falling cup barrel 314 is set to be the size that one reaction cup 700 can only fall down, so that a plurality of reaction cups 700 can fall down smoothly in sequence, and the chaotic condition that a plurality of reaction cups 700 fall down simultaneously can not occur.

As shown in fig. 13, the push cup assembly 307 includes a push member 3071, a guide rail 3072, a second linear drive 3074, and a first linear drive 3073; the guide rail 3072 is mounted to an outer sidewall of the transport guide block 310 in a first direction; the second linear driving member 3074 is used for driving the pushing member 3071 to move towards or away from the reaction cup 700 in the cup falling channel 313 along a second direction, and the first direction and the second direction are intersected; the first linear drive 3073 is mounted to the rail 3072 for driving the second linear drive 3074 in a linear motion in a first direction.

Wherein, the first linear driving member 3073 and the second linear driving member 3074 are both in the form of a conventional linear driving structure of a driving motor and a rotary screw. The first direction in the present embodiment refers to the front-rear direction in fig. 13, and the second direction refers to the left-right direction in fig. 13. The rotating screw rod of the first linear driving member 3073 is spirally sleeved with a sliding block, one side of the sliding block is in sliding contact fit with the guide rail 3072, the other side of the sliding block is connected with the second linear driving member 3074, and when the rotating screw rod of the first linear driving member 3073 rotates, the sliding block can be driven to slide along the guide rail 3072.

When the cup pushing action is performed, the second linear driving piece 3074 drives the pushing piece 3071 to move leftwards so as to contact the reaction cup 700, and then the first linear driving piece 3073 drives the second linear driving piece 3074 to move along the front-back direction so as to push the reaction cup 700 to move towards the cup falling opening 315, and the cup falling is realized when the reaction cup 700 reaches the cup falling opening 315; with this reciprocation, the sequential cup falling of the plurality of reaction cups 700 in the cup falling passage 313 is completed, and the cup clamping phenomenon is prevented in the cup arranging process.

In an embodiment, the cup arranging module 300 further includes a determining element, where the determining element is a determining optocoupler 312, and the determining optocoupler 312 is disposed near the cup falling opening 315 and is used for determining whether the reaction cup 700 falls at the cup falling opening 315. The cup arranging module 300 further comprises a control unit electrically connected with the judging optocoupler 312, when the judging optocoupler 312 recognizes that the cup falling opening 315 is provided with the reaction cup 700 to wait for falling, the control unit controls the cup pushing assembly 307 to stop the cup pushing action of the next reaction cup 700; when it is judged that the optocoupler 312 recognizes that the cup falling opening 315 does not have the reaction cup 700, the control unit controls the cup pushing assembly 307 to act so as to push the next reaction cup 700 to the cup falling opening 315 to wait for falling. This way, the reaction cup 700 can fall from the cup falling opening 315 efficiently and smoothly without disorder.

In one embodiment, the first rotary driving assembly 306 comprises a large synchronizing wheel, a small synchronizing wheel, a synchronous belt wound around the peripheries of the large synchronizing wheel and the small synchronizing wheel, and a fourth rotary driving member coaxially connected with the small synchronizing wheel, wherein the large synchronizing wheel is mounted on the side of the cup arranging drum 302 facing the reaction cup charging bin 301. Wherein the fourth rotary driving member is preferably a servo motor; the servo motor drives the small synchronous wheel to rotate in a rotating way, so that the large synchronous wheel is driven to rotate synchronously; because the large synchronizing wheel is arranged on the periphery of the cup arranging rotary drum 302, the large synchronizing wheel can drive the whole cup arranging rotary drum 302 to radially rotate at the same time when rotating.

As shown in fig. 14 to 17, the present application provides an incubation module 400 including an incubation tray, a stirring assembly 401, a second rotary drive assembly 402, an optocoupler assembly, and a control unit; the incubation plate comprises a rotation plate 403 and a reaction plate 404, wherein the rotation plate 403 is provided with a plurality of through holes 405 for accommodating the reaction cups 700 along the circumferential direction, a reaction cup accommodating station 406 for inserting the bottoms of the reaction cups 700 is formed on the reaction plate 404, and the reaction plate 404 is used for incubating and heating the reaction cups 700; the stirring assembly 401 is arranged below the reaction disk 404 and is used for stirring and uniformly mixing the reagent and the sample in the reaction cup 700; the second rotary driving assembly 402 is used for driving the rotary disk 403 to rotate; the optocoupler component is arranged on the reaction disk 404, acquires the corresponding position information of the through hole 405 and the reaction cup accommodating station 406, and sends out a judging signal; the control unit is electrically connected with the optocoupler assembly and controls the second rotary driving assembly 402 to act according to the received judging signal, and the through holes 405 and the reaction cup accommodating stations 406 are in one-to-one correspondence with the rotation of the rotary disc 403.

The incubation plate can ensure that on the premise that all the reaction cups 700 are fully incubated at the incubation temperature, only the reaction cups 700 needing to be evenly mixed with reagents are effectively evenly mixed, other reaction cups 700 are not affected, redundant parts are not needed, the whole incubation plate is simple in structure, stable and reliable in operation, and the reaction cups 700 are completely incubated. And integrating multiple components onto the incubation plate improves modular production and sample analysis of the entire incubation module 400.

In an embodiment, a mounting plate is further arranged below the reaction plate 404, the stirring assembly 40 is positioned on the mounting plate, and the stirring assembly 401 comprises a first rotary driving piece 4011, a stirring switching shaft 4012 and a stirring oscillating shaft 4013; the top end of the stirring adapter shaft 4012 forms a stirring groove for inserting the bottom of the reaction cup 700, and the stirring groove is of a cylindrical eccentric structure; the bottom of stirring oscillation shaft 4013 is connected with first rotary driving piece 4011 drive, and stirring switching axle 4012 is connected on stirring oscillation shaft 4013's top. When one of the reaction cups 700 needs to be uniformly mixed, the second rotary driving assembly 402 drives the rotary disc 403 to rotate, so that the reaction cup 700 rotates to a position where the reaction cup 700 is in butt joint with the stirring adapter shaft 4012, and at the moment, the first rotary driving member 4011 drives the stirring oscillation shaft 4013 to rotate and oscillate, so that the rotation of the reaction cup 700 can be realized. Wherein, because the stirred tank is eccentric structure, when stirring adapter shaft 4012 drove reaction cup 700 rotatory like this, can improve the mixing effect of reaction cup 700.

In one embodiment, the rotating disk 403 includes a rotating ring 4031 coaxially disposed at intervals on the inner periphery of the reaction disk 404 and a rotating cover plate 4032 covering the rotating ring 4031, the outer peripheral wall of the rotating ring 4031 has external gear teeth, and the second rotary driving assembly 402 includes a second rotary driving member disposed between the rotating ring 4031 and the reaction disk 404 and a gear coaxially connected with the second rotary driving member. Wherein, the rotating cover 4032 and the rotating ring 4031 are connected and located above the reaction plate 404, in order to realize the rotation of the rotating ring 4031, gear teeth are formed on the outer periphery of the rotating ring 4031, and the second rotation driving assembly 402 may be a structure formed by combining a rotating motor and a gear, and the gear is meshed with the outer periphery of the rotating ring 4031, so that the rotating ring 4031 can rotate with the gear.

In one embodiment, the incubation module 400 further comprises a mounting table 407, a wash priming assembly 408, and a lift drive assembly 409; the number of the cleaning and liquid injection components 408 is at least two, and the cleaning and liquid injection components 408 are arranged on the mounting table 407 at intervals along an arc shape, and in the rotation direction along the rotating cover plate 4032, the last cleaning and liquid injection component 408 is used for sucking the residual liquid in the reaction cup 700, and the rest cleaning and liquid injection components 408 are used for sucking the liquid in the reaction cup 700 and injecting cleaning liquid; the lift drive assembly 409 is mounted on the reaction plate 404 and is used to lift the mounting block 407 to drive the cleaning and priming assembly 408 away from or into the reaction cup 700.

In the cleaning process, the rotating disc 403 is driven to rotate, and when the plurality of reaction cup accommodating stations 406 rotate below the cleaning and liquid injecting components 408, the lifting driving component 409 drives the cleaning and liquid injecting components 408 to descend and correspondingly insert into the reaction cups 700, and each reaction cup 700 needs to be cleaned in multiple stages through multiple groups of cleaning and liquid injecting components 408. In the rotation direction of the rotating disc 403, in each cleaning process, the plurality of groups of cleaning and liquid injection assemblies 408 positioned in front firstly suck the liquid in the reaction cup 700 and then inject the cleaning liquid for cleaning; when the reaction cup 700 rotates to the last cleaning liquid injection component 408, all the residual liquid in the reaction cup 700 needs to be sucked away, so that the multi-group cleaning liquid injection component 408 can complete multi-stage cleaning of one reaction cup 700, the cleaning effect is ensured, and the whole cleaning process is high in automation degree and beneficial to modularized production. In addition, since the plurality of groups of cleaning liquid injection components 408 are arranged on the mounting table 407 at intervals along an arc, in order to improve cleaning efficiency, the orthographic projections of the plurality of groups of cleaning liquid injection components 408 are all located on the circumference where the plurality of reaction cup accommodating stations 406 are located.

In one embodiment, the purge fill assembly 408 includes a guide sleeve and a reaction needle integrally integrated within the guide sleeve; the guide sleeve movably penetrates through the mounting table 407; the reaction needle is used to suck up the liquid in the reaction cup 700 or to inject the cleaning solution into the reaction cup 700. Wherein, in the rotation direction of the rotating disk 403, the last reaction needle comprises a sucking needle 4081 for sucking the liquid in the reaction cup 700, and the rest reaction needles comprise a liquid injection needle 4082 for injecting the cleaning liquid into the reaction cup 700 and a sucking needle 4081 for sucking the liquid in the reaction cup 700. Wherein, the upper end of the sucking needle 4081 is externally connected with a sucking power device to provide sucking power for sucking liquid of the sucking needle 4081; the upper end of the filling needle 4082 is externally connected with a container containing cleaning liquid and a driving device, and the driving device pumps the cleaning liquid into the filling needle 4082 to fill the reaction cup 700 with the cleaning liquid.

In the preferred embodiment, as shown in fig. 16, the number of the cleaning and priming members 408 is five, and in the case where the rotating disk 403 rotates clockwise, the reaction needles in the cleaning and priming members 408 located four-way ahead in the direction of rotation of the rotating disk 403 each include a suction needle 4081 and a priming needle 4082; at the four front stations, the liquid in the corresponding reaction cup 700 is sucked away by adopting a suction needle 4081, and then a new cleaning liquid is injected into the reaction cup 700 by adopting a liquid injection needle 4082 so as to clean the residual solvent in the reaction cup 700; the wash priming assembly 408 in the final position includes a suction needle 4081 for sucking all of the remaining liquid from the cuvette 700. Since the sucking needle 4081 is required to suck the liquid in the reaction cup 700, and the injecting needle 4082 is required to inject the cleaning liquid into the reaction cup 700, the plane of the bottom of the sucking needle 4081 is higher than the plane of the bottom of the injecting needle 4082, so that the sucking needle 4081 can contact the bottom of the reaction cup 700 to suck the liquid in the reaction cup 700 completely under the condition of lowering a certain height.

In one embodiment, the wash infusion assembly 408 further comprises a mounting block 4083, a guide post 4084, and a resilient member 4085; the mounting block 4083 is attached to the mounting table 407, and a mounting hole for the guide sleeve to penetrate is formed in the mounting block 4083; the guide post 4084 is mounted on the mounting table 407 and movably penetrates through the mounting block 4083, and is arranged at intervals along the rotation direction of the reaction disk 404 with the guide sleeve, and a convex ring is formed at the top end of the guide post 4084; the elastic element 4085 is wound around the periphery of the guide post 4084, and the elastic element 4085 is elastically compressed between the convex ring and the mounting block 4083, so that the elastic element 4085 always applies elastic acting force to the mounting block 4083, and the mounting block 4083 and the mounting table 407 are always attached. When the elevation driving assembly 409 drives the mounting table 407 to move upward, the mounting block 4083 is allowed to fit the mounting table 407 and move upward together with the mounting table 407 due to the elastic member 4085 applying a downward elastic force to the mounting block 4083; the mounting table 407 and the guide sleeve are integrally formed, so that the guide sleeve and the reaction needle can be driven to move upwards together by the lifting of the mounting table 407 until the reaction cup 700 is separated. When the elevation drive assembly 409 drives the mounting block 407 downward, the mounting block 407 moves downward along with the guide sleeve until the reaction needle is inserted into the reaction cup 700. It should be noted that, when the sucking needle 4081 moves downward and contacts the bottom of the reaction cup 700, the elastic member 4085 can play a role in buffering the downward movement process, preventing the bottom end of the sucking needle 4081 from being damaged.

In one embodiment, the lift drive assembly 409 includes a rotary screw, a third rotary drive, a slide rail, and a connection block; a rotary nut is sleeved on the rotary screw rod in a spiral way; the third rotary driving piece is used for driving the rotary screw rod to rotate, wherein the third rotary driving piece is a screw rod driving motor, and the driving end of the screw rod driving motor is connected with the rotary screw rod and used for driving the rotary screw rod to rotate; the sliding rail is connected to the rotating nut, and the top end of the sliding rail is detachably connected with the mounting table 407; the connecting block is in sliding fit with the sliding rail along the height direction. When lifting driving is needed, the screw rod driving motor rotates to drive the rotary screw rod to rotate, so that the rotary nut sleeved on the rotary screw rod can move up and down relative to the rotary screw rod, and the sliding rail connected to the rotary nut also moves up and down along with the rotary nut, so that the mounting table 407 is driven to move. Because the side of the sliding rail, which is away from the rotating nut, is in sliding fit with the connecting block, the sliding rail drives the cleaning and liquid injection component 408 to move up and down relative to the whole reaction disk 404, so that the purpose that the cleaning and liquid injection component 408 is far away from or inserted into the reaction cup 700 is realized.

In one embodiment, the outer peripheral wall of the reaction disk 404 is provided with magnetic attraction pieces, and the magnetic attraction pieces are disposed at positions corresponding to the cleaning and liquid injection components 408, and can magnetically attract the magnetic beads in the reaction cup 700. When the rotating disc 403 rotates, the reaction cups 700 at the front four reaction cup accommodating stations 406 are respectively provided with a magnetic attraction piece, and when the rotating disc 403 stops rotating, the magnetic attraction pieces and the magnetic beads in the corresponding reaction cups 700 are attracted, so that the magnetic beads of the reaction cups 700 are attracted to the inner wall of the reaction cups 700. When the sucking needle 4081 of the cleaning and liquid injecting component 408 sucks the liquid of the reaction cup 700, the existence of the magnetic beads does not influence the adsorption of the sucking needle 4081, and the magnetic beads adsorbed on the inner wall by the magnetic attraction piece cannot enter the sucking needle 4081; after the liquid is sucked, the liquid injection needle 4082 washes the inside of the reaction cup 700, on one hand, the magnetic beads on the inner wall of the reaction cup 700 can be washed by using the washing liquid, and the magnetic beads are dispersed into the reaction cup 700 and are not aggregated any more, so that the residual reagent on the magnetic beads is washed into the reaction cup 700; on the other hand, the injection needle 4082 can flush the outer wall of the suction needle 4081, so that the stuck reagent on the outer wall of the suction needle 4081 is flushed into the reaction cup 700. The reaction cup 700 after the previous flushing process is moved to the lower part of the next cleaning and liquid injection assembly 408 under the driving of the rotating disc 403 to prepare for secondary cleaning, after multiple cleaning, when the reaction cup 700 moves to the lower part of the last cleaning and liquid injection assembly 408, the sucking needle 4081 sucks all the residual liquid in the reaction cup 700, so that the multiple cleaning process of one reaction cup 700 is completed.

In one embodiment, the optocoupler assembly includes a position mating member and a position optocoupler 411; the number of the position matching pieces is multiple, and the position matching pieces are circumferentially arranged on the rotating disc 403 and correspond to the reaction cup accommodating stations 406 one by one; the position optical coupler 411 cooperates with the position matching part to acquire the position information of the reaction cup accommodating station 406, and sends out a judging signal according to the position information. The reaction disc 404 is provided with annular grooves along the circumferential direction, a plurality of reaction cup accommodating stations 406 are formed in the annular grooves at intervals, as shown in fig. 5, the top end surface of the rotating disc 403 is provided with a plurality of through holes 405 along the circumferential direction, each through hole 405 can be provided with a reaction cup 700, the bottom of the reaction cup 700 is inserted into the annular groove, when the rotating disc 403 drives the reaction cup 700 to rotate, the annular groove plays a role in guiding, and the reaction cup 700 can move along the extending direction of the annular groove in a guiding manner. Compared with the technical scheme that the reaction disk 404 does not have the position judging and identifying functions in the prior art, the application can accurately control the pause of the rotating disk 403 to add samples or reagents into the reaction cup 700 by identifying whether the reaction cup 700 reaches the position of the reaction cup accommodating station 406 or not through arranging the position optical coupler 411 and the position matching part which can judge the reaction cup accommodating station 406 on the reaction disk 404, and ensure the accuracy of the sample or reagent addition.

In an embodiment, the optocoupler assembly further includes a reset optocoupler disposed on the reaction plate 404 and a light blocking post disposed on the rotating plate 403, where the reset optocoupler and the light blocking post cooperate to detect whether the rotating plate 403 reaches a reset initial position. Thus, when the reaction cup 700 on the reaction plate 404 finishes the sample addition, the rotation plate 403 rotates to the initial position; when the light blocking column moves to the position of the reset optocoupler during rotation of the rotating disk 403, the reset optocoupler recognizes the light blocking column and sends out a reset in place signal indicating that the rotating disk 403 has been reset to the initial position at this time. Preferably, both the reset optocoupler and the position optocoupler 411 may be optocoupler sensors as is common in the art.

Specifically, in the first embodiment, as shown in fig. 18, the position matching members are reaction hole sites 410 formed on the peripheral wall of the rotary cover 4032, the reaction hole sites 410 are disposed corresponding to the positions of the through holes 405, the reaction hole sites 410 may be in the form of U-shaped slots, and the number of the reaction hole sites 410, the number of the through holes 405 and the number of the reaction cup receiving stations 406 are the same. When the rotating disk 403 rotates to a proper position, the reaction holes 410, the through holes 405 and the reaction cup accommodating stations 406 can be in one-to-one correspondence. For example, when the rotating disc 403 rotates, the position optocoupler 411 always detects the reaction hole site 410, and when the reaction hole site 410 does not correspond to the position of the position optocoupler 411, the position optocoupler 411 sends out an electrical signal of "0"; when the reaction well 410 corresponds to the position of the position optocoupler 411, the position optocoupler 411 sends out a "1" signal, indicating that the reaction well 410 moves to the position corresponding to the cuvette receiving station 406 at this time, and reagent or sample can be added to the cuvette 700.

As shown in fig. 19 to 21, the cup-dropping module 800 of the present application includes a gripping mechanism 801, a cup-dropping push block 802, a lifting drive mechanism 803, and a translation mechanism 804; the grabbing mechanism 801 comprises an elastic clamping piece 8011, a lifting plate 8012 and two clamping bodies 8013 which are in sliding connection with the lifting plate 8012, wherein the two clamping bodies 8013 are oppositely arranged along a third direction and enclose a clamping groove, and two ends of the elastic clamping piece 8011 are respectively correspondingly connected with the two clamping bodies 8013; the cup-dropping push block 802 is located between the two clamping bodies 8013 and is used for abutting the two clamping bodies 8013, so that the two clamping bodies 8013 slide back to back along a third direction; the lifting driving mechanism 803 is used for driving the lifting plate 8012 to reciprocate between a grabbing position and a material dropping position along a fourth direction relative to the cup dropping pushing block 802; wherein, the reaction cup 700 can extend into the clamping groove at the grabbing position and tension the elastic clamping piece 8011, so that the elastic clamping piece 8011 applies elastic clamping force to the clamping body 8013, the cup-dropping push block 802 can squeeze the clamping body 8013 at the position of the cup-dropping, and the two clamping bodies 8013 can slide back to back along the third direction against the elastic clamping force and loosen the reaction cup 700; the translation mechanism 804 is used for driving the lifting driving mechanism 803 and the grabbing mechanism 801 to synchronously translate along a third direction. It can be understood that, in the present embodiment, the third direction is the left-right direction in fig. 19, the fourth direction is the up-down direction, the lifting driving mechanism 803 can drive the lifting plate 8012 to lift in the up-down direction, and the translating mechanism 804 can drive the grabbing mechanism 801, the cup dropping pushing block 802 and the lifting driving mechanism 803 to translate synchronously in the left-right direction.

Before the reaction cup 700 is grabbed by the application, the reaction cup 700 can be placed on one side close to the clamping groove, so that the cup-dropping push block 802 and the reaction cup 700 are oppositely arranged, at the moment, the clamping bodies 8013 are positioned between the cup-dropping push block 802 and the reaction cup 700, under the condition that the reaction cup 700 needs to be grabbed, the lifting driving mechanism 803 drives the lifting plate 8012 to drive the clamping bodies 8013 to move to the grabbing position along the fourth direction, in the process of moving to the grabbing position, the reaction cup 700 is positioned between the two clamping bodies 8013, can simultaneously abut against the two clamping bodies 8013, the size of the reaction cup 700 is larger than the size of the clamping groove, can drive the two clamping bodies 8013 to overcome the elasticity of the elastic clamping piece 8011, the two clamping bodies 8013 synchronously slide back along the third direction until the clamping bodies 8013 move to the grabbing position, the reaction cup 700 stretches into the clamping groove, the elastic clamping piece 8011 is tensioned, the elastic clamping bodies 8011 can be driven by the elastic clamping pieces 8011 to apply elastic clamping force to the clamping bodies 8013, the clamping bodies 8013 under the action of the elastic clamping force, in the process of moving to the grabbing position, the clamping bodies 8013 can be moved to the position along the specified direction, the size of the clamping mechanism 802 is finished, the size of the clamping bodies 802 is larger than the size of the clamping groove, the clamping bodies 8013 can be moved back to the position along the specified direction, and the three-dropping position is moved back to the clamping mechanism 803, and the size of the clamping body 8013 can move to the clamping body 8013 synchronously along the position along the direction, and the three direction is moved to move back along the clamping mechanism 803, and the position along the direction of the direction, and the position is moved to move the position along the clamping body 8013. The grabbing manner has a simple structure, and the clamping body 8013 and the lifting plate 8012 are connected in a sliding manner, so that the abrasion of the grabbing mechanism 801 can be reduced by the sliding manner, and the service life of the cup grabbing mechanism can be prolonged.

As shown in fig. 20, in an embodiment, the grabbing mechanism 801 further includes a first horizontal rail 8014 and a sliding assembly, where the first horizontal rail 8014 is disposed on the lifting plate 8012; the sliding assembly is detachably connected with the clamping body 8013, and the sliding assembly is provided with a sliding groove in sliding contact fit with the first horizontal guide rail 8014. Through sliding component sliding connection between lifter plate 8012 and the clamping body 8013, and sliding component and clamping body 8013 can dismantle the connection, under the circumstances that sliding component or clamping body 8013 damaged, can change sliding component or clamping body 8013 alone, make things convenient for the maintenance and the change of grabbing the cup mechanism greatly, need not to snatch mechanism 801 and wholly change, reduced the use cost of grabbing the cup mechanism.

In one embodiment, the sliding assembly includes a wear-resistant slider 8015 and a second connecting plate 8016, and the sliding slot is formed on one side of the wear-resistant slider 8015; the second connecting plate 8016 is detachably connected with the other side of the wear-resistant sliding block 8015, the clamping body 8013 is provided with a positioning groove matched with the second connecting plate 8016 in a positioning way, the second connecting plate 8016 is provided with a clamping groove clamped with the wear-resistant sliding block 8015, and the clamping body 8013 is detachably connected with the second connecting plate 8016. And can be after the constant head tank of the clamping body 8013 and the preliminary location of the second connecting plate 8016, the rethread can dismantle the connecting piece and further connect clamping body 8013 and second connecting plate 8016, can make things convenient for the assembly between clamping body 8013 and the second connecting plate 8016, improved the assembly accuracy simultaneously, can reduce assembly error. It should be noted that, the clamping body 8013 is provided with a roller 8017 in rolling contact with the cup-throwing push block 802, the two clamping bodies 8013 enclose an avoidance groove into which the cup-throwing push block 802 extends, and the roller 8017 is disposed near the avoidance groove. In this embodiment, the roller 8017 is located at the top of the clamping body 8013, and the cup-dropping push block 802 can extend into a gap between the two rollers 8017 and be matched with the two rollers 8017 in a rolling contact manner, and in this embodiment, the cup-dropping push block 802 and the clamping body 8013 are pushed against each other in a rolling contact manner, so that friction and loss between the cup-dropping push block 802 and the clamping body 8013 can be reduced, and the service life of the cup grabbing mechanism is further ensured. In order to facilitate the cup throwing push block 802 to further push the clamping body 8013, an avoidance groove for the cup throwing push block 802 to extend into is arranged between the roller 8017 and the clamping groove, so that the use convenience of the cup grabbing mechanism is improved.

As shown in fig. 21, a positioning column 8018 is disposed on the lifting plate 8012 along a third direction between two clamping bodies 8013, the positioning column 8018 is disposed between the avoiding groove and the clamping groove along a fourth direction, and the clamping bodies 8013 are provided with a limiting groove in limiting fit with the positioning column. The positioning column 8018 in this embodiment is located between the avoidance groove and the clamping groove, the positioning column 8018 is cylindrical and extends along the front-rear direction, the limiting groove is semicircular, the two clamping bodies 8013 are enclosed outside the positioning column 8018, and under the condition that the cup-throwing push block 802 or the reaction cup 700 pushes the clamping bodies 8013, the positioning column 8018 can separate the two clamping bodies 8013 from each other, so that the situation that the two clamping bodies 8013 move in the same direction can be avoided, and the use efficiency of the cup grabbing mechanism can be improved.

In one embodiment, the end of the clamping groove facing the reaction cup 700 is provided with a guide part with an opening, and the cross-sectional dimension of the guide part gradually decreases from the opening along the fourth direction; and, one end of the cup-throwing push block 802 facing the clamping body 8013 is provided with a guiding tip, and the guiding tip is provided with a guiding inclined plane for contacting with the surface of the clamping body 8013. The guiding part in this embodiment is provided with a chamfer design, and can guide the reaction cup 700 under the condition that the reaction cup 700 abuts against the clamping body 8013, so that the reaction cup 700 can conveniently enter the clamping groove. In this embodiment, the inner ring of the clamping body 8013 is provided with a chamfer, when the clamping body 8013 is driven to move downwards, the clamping body 8013 overcomes the force of the elastic clamping piece 8011 and opens to clamp the reaction cup 700 through the chamfer, then the clamping body 8013 is clamped by the elastic clamping piece 8011 to clamp the reaction cup 700, and the lifting driving mechanism 803 drives the clamping body 8013 to move upwards, so as to realize the transfer of the reaction cup 700. In this embodiment, the cup-throwing push block 802 is integrally provided with a T-shape, and the lower end of the cup-throwing push block is provided with a guiding tip, and the guiding inclined surface of the guiding tip can be in rolling contact fit with the roller 8017.

In one embodiment, the translation mechanism 804 comprises a translation driving member 8041, a transverse supporting plate 8042, a transmission assembly and a tensioning assembly 8043, the transverse supporting plate 8042 is provided with a second horizontal guide rail 3072, the translation driving member 8041 is mounted on the transverse supporting plate 8042, and the lifting driving mechanism 803 is in sliding contact fit with the second horizontal guide rail 3072; the transmission assembly is arranged on the transverse supporting plate 8042 and comprises a transmission wheel and a transmission chain in transmission connection with the transmission wheel, and the translation driving piece 8041 is used for driving the transmission wheel to rotate; the number of the driving wheels is at least two, and the tensioning adjusting component 8043 is connected with one driving wheel and used for adjusting the interval between the driving wheels so as to tension the driving chain.

In this embodiment, the translation driving member 8041 may be a motor, the translation driving member 8041 may drive the driving wheel to rotate, the driving wheel drives the translation sliding plate to translate along the second horizontal guide rail 3072 through the driving belt, the second horizontal guide rail 3072 extends along the left-right direction, under the condition that the driving chain is loose when the driving chain is used for a long time, the interval between the driving wheels can be adjusted by the tensioning adjusting assembly 8043, and the driving chain sleeved outside the driving wheel is tensioned, so that the condition that the driving chain is not smooth due to the loose driving chain is avoided.

The number of the driving wheels is preferably two, the tensioning adjusting component 8043 is located between the two driving wheels, the tensioning adjusting component 8043 can comprise an adjusting piece and an adjusting plate, the adjusting plate is connected with the central shaft of the driving wheels, the adjusting plate is provided with an adjusting inclined plane provided with an adjusting groove, and the pressure of the adjusting plate to the driving wheels can be adjusted through the position of the adjusting piece in the adjusting groove, so that the interval between the driving wheels is adjusted.

It will be appreciated that the cup grabbing mechanism further comprises a first sensor mounted at an initial position on the lateral support plate 8042 and a second sensor mounted at a final position on the lateral support plate 8042, the grabbing mechanism 801 being located between the initial position and the final position in the third direction, the first sensor and the second sensor being configured to detect the grabbing mechanism 801, the cup rest push block 802, the lift drive mechanism 803 and to deactivate the translational drive 8041 in case of detecting the grabbing mechanism 801, the cup rest push block 802 or the lift drive mechanism 803. In an embodiment, the first sensor and the second sensor may both adopt photoelectric sensors, the transverse supporting plate 8042 extends along the left-right direction, two blocking sheets are respectively and correspondingly arranged on the translation sliding plate and respectively correspond to the first sensor and the second sensor on the transverse supporting plate 8042, the two blocking sheets are used as detection structures, and the translation driving member 8041 is turned off under the condition that the blocking sheets are detected by the first sensor and the second sensor. In other embodiments, detection structures corresponding to the first and second sensors may be provided at other locations on the grasping mechanism 801, the cup-lost push block 802, and the lift drive 803, with the first and second sensors disabling the translation drive 8041 upon detection of the detection structures. The first sensor is close to the right end setting of horizontal guide 3072, and the second sensor is close to the left end setting of horizontal guide 3072, specifically through first sensor and second sensor accessible response snatchs mechanism 801, loses cup ejector pad 802, lift actuating mechanism 803 in this embodiment, judges whether the clamping body 8013 is located the position and targets in place, can realize the automation that translation actuating member 8041 closed completely, has improved the operating convenience who grabs the cup mechanism.

In an embodiment, as shown in fig. 19, the cup grabbing mechanism further includes a bracket 805 supporting the transverse support plate 8042, and a third sensor is disposed on the bracket 805 corresponding to the final position, and is used for detecting the reaction cup 700, and starting the lifting driving mechanism 803 when the reaction cup 700 is detected, so that the lifting driving mechanism 803 drives the clamping body 8013 to move to the material-dropping position.

In one embodiment, lift drive 803 includes a translational sled, a lift drive, and a fourth sensor; the translation slide plate is provided with a lifting guide rail 3072, the lifting plate 8012 is in sliding contact fit with the lifting guide rail 3072, and the translation mechanism 804 is used for driving the translation slide plate to translate; the lifting driving piece is arranged on the translation sliding plate and used for driving the lifting plate 8012 to lift; the fourth sensor is installed in the translation slide, and the fourth sensor is used for closing the lift drive under the condition that detects that the clamping body 8013 is located and loses the position. The lifting driving piece in this embodiment may be a motor, the output end of the motor may be connected with a screw rod, the lifting plate 8012 may be provided with a threaded hole in threaded connection with the screw rod, the screw rod extends along the up-down direction under the condition that the motor drives the screw rod to rotate forward or reversely, the lifting plate 8012 may lift along the screw rod, and meanwhile, the lifting plate 8012 and the lifting guide rail 3072 are in guiding fit, so that the accuracy of the lifting track of the lifting plate 8012 may be ensured. The fourth sensor in this embodiment may be a photoelectric sensor, and a photoelectric shutter 305 extending into a photoelectric cell of the photoelectric sensor may be mounted on the lift plate 8012.

For ease of understanding, the working principle of the whole sample analysis device is further described as follows: firstly, storing a reagent required in the reaction process in a reagent bin module, and uniformly mixing and refrigerating the reagent through the reagent bin module; the sample injection module is used for storing a sample tube and has a code scanning identification function and a cover function, and the cup arranging module is used for placing the reaction cup in the incubation module to wait for incubation reaction; when the test is started, the reagent transfer module is used for transferring the sample in the sample injection module into the reaction cup in the incubation module, transferring the reagent in the reagent bin module into the reaction cup in the incubation module, reacting with the sample in the reaction cup, and transferring the reagent in the reaction cup to the detection module for detection analysis after the cleaning of the cleaning and liquid injection assembly is completed. After detection analysis is completed, the cup-losing module can absorb the residual liquid in the reaction cup after cleaning to the waste liquid barrel and then clamp and discard the residual liquid to the waste recycling module. The whole sample analysis device has high automation degree, improves the detection efficiency, integrates a plurality of modules on the rack, and improves the space utilization rate.

Claims (13)

1. A sample analysis device, comprising a frame and a plurality of sample analysis devices disposed on the frame:

A reagent cartridge module (100) for storing reagents required in the reaction process;

a sample injection module (200) for storing a sample tube (17);

the cup arranging module (300) is used for arranging the empty reaction cups (700) and vertically arranging the empty reaction cups (700) to the discharging end in sequence;

The incubation module (400) is connected with the blanking end of the cup arranging module (300), and the incubation module (400) is used for receiving and accommodating the empty reaction cups (700) conveyed by the cup arranging module (300);

The transfer module (500) moves among the reagent bin module (100), the sample injection module (200) and the incubation module (400), the transfer module (500) is used for transferring the sample in the sample injection module (200) and the reagent in the reagent bin module (100) to the reaction cup (700) in the incubation module (400), and the incubation module (400) is used for uniformly mixing the reagent in the reaction cup (700) and the sample for incubation reaction; and

A detection module (600) for detecting a reagent that completes the incubation reaction in the incubation module (400).

2. The sample analysis device according to claim 1, wherein the reagent cartridge module (100) comprises:

A bin body (1);

The mixing mechanism (2) is arranged in the bin body (1) and is used for mixing samples;

The first refrigerating unit (3) and the second refrigerating unit (4) are used for refrigerating the bin body (1) and are arranged below the bin body (1) at intervals in the transverse direction, and the first refrigerating unit (3) and the second refrigerating unit (4) are distributed in the longitudinal direction;

The third driving mechanism is arranged between the first refrigerating unit (3) and the second refrigerating unit (4) and comprises a driving motor, a driving shaft (503) and synchronous pulley assemblies (502) distributed along the longitudinal direction, the top end of the driving shaft (503) upwards penetrates through the bottom wall of the bin body (1) and is connected with the mixing mechanism (2), the bottom end of the driving shaft (503) is connected with the synchronous pulley assemblies (502), and the driving motor is arranged along the vertical direction and is used for driving the synchronous pulley assemblies (502).

3. The sample analysis device of claim 2, wherein the reagent cartridge module (100) further comprises:

a sample tube (17) detachably inserted into the mixing mechanism (2);

the reset component is used for resetting the mixing mechanism (2) and comprises:

A reset optocoupler (1601) disposed on top or bottom of a driven wheel of the synchronous pulley assembly (502) and formed with a first detection portion;

A reset optocoupler (1602) disposed on a side of the driven wheel away from the driving motor and configured to detect the first detection portion;

A position detection assembly for detecting a rotational position of the sample tube (17) and comprising:

the position detection optocoupler (1801) is arranged on the driven wheel and vertically spaced from the reset optocoupler (1601), and a plurality of second detection parts distributed at intervals along the circumferential direction are formed on the position detection optocoupler (1801);

And the position detection optocoupler (1802) is vertically arranged at intervals with the reset optocoupler (1602) and is used for detecting the second detection part.

4. A sample analysis device according to claim 3, wherein the reagent cartridge module (100) further comprises:

the first cold insulation plate (13) is arranged at the bottom of the bin body (1);

The motor mounting seat (14) is arranged below the first cold insulation plate (13), and a first mounting cavity (15) is formed between the motor mounting seat (14) and the first cold insulation plate (13);

The driving wheel of the synchronous pulley assembly (502) is arranged in the first installation cavity (15) along the horizontal direction, and the driving end of the driving motor upwards penetrates through the bottom wall of the motor installation seat (14) and is in driving connection with the driving wheel;

An optocoupler mounting base (19) for mounting the reset optocoupler (1602) and the position detection optocoupler (1802);

The second cold insulation plate (20) is arranged below the bin body (1) and used for installing the optocoupler installation seat (19).

5. The sample analysis device according to claim 1, wherein the sample introduction module (200) comprises:

a mounting platform (21) provided with a sample conveying area (22) and a cover opening area (23) positioned at one lateral side of the sample conveying area (22);

A sample tray (202) longitudinally movably provided in the sample conveying area (22) and formed with a first conveying path for loading a sample rack (203);

A sampling rail (204) which is provided in the cover opening area (23) in the lateral direction and can communicate with the first conveyance path;

A first drive mechanism disposed below the sampling track (204) and configured to drive a sample rack (203) on the sample tray (202) to and from the first transport path and the sampling track (204);

The compressing mechanism (206) is arranged on one longitudinal side of the cover opening area (23) and positioned on one longitudinal side of the sampling track (204) and is used for compressing the tube body of the sample tube (17);

And the cover opening mechanism (208) is arranged in the cover opening area (23) and is positioned on one side of the pressing mechanism (206) away from the sampling track (204) and is used for opening the tube cover of the sample tube (17).

6. The sample analysis device of claim 5, wherein the number of first transport channels is a plurality, and the sample injection module (200) further comprises:

Sensing means for sensing a sample rack (203) entering the first transport path;

A second drive mechanism (213) for driving the sample tray (202) to a position in which the first transport path is flush with the sampling track (204).

7. The sample analysis device according to claim 5, wherein the sample introduction module (200) further comprises a lifting mechanism (220) and a connecting arm (221), the lifting mechanism (220) being liftably arranged on the mounting platform (21) and being located at a side of the hold-down mechanism (206) remote from the sample holder (203), the connecting arm (221) being arranged at the top of the lifting mechanism (220);

The cover opening mechanism (208) comprises a cover opening driving piece (2081), a pivot shaft (2082) and two clamping pieces (2083), the pivot shaft (2082) is vertically arranged on the connecting arm (221), the clamping pieces (2083) comprise a connecting part and a clamping part, the upper end of the clamping part is connected with the connecting part and can clamp a tube cover of the sample tube (17) from the upper end and the lower end, the connecting part is rotatably arranged on the pivot shaft (2082) along the horizontal direction, a clamping space for clamping the tube cover is formed between the two clamping parts, and the cover opening driving piece (2081) is arranged above the connecting arm (221) along the horizontal direction and is used for driving the two clamping parts to be close to or far away from each other.

8. The sample analysis device according to claim 1, wherein the incubation module (400) comprises:

The incubation plate comprises a rotating plate (403) and a reaction plate (404), wherein a plurality of through holes (405) for accommodating the reaction cups (700) are formed in the rotating plate (403) along the circumferential direction, and a reaction cup accommodating station (406) for inserting the bottoms of the reaction cups (700) is formed on the reaction plate (404);

The stirring assembly (401) is arranged below the reaction disc (404) and is used for stirring and uniformly mixing the reagent and the sample in the reaction cup (700);

A second rotary drive assembly (402) for driving the rotary disk (403) in rotation;

The optocoupler component is arranged on the reaction disc (404) and used for acquiring the corresponding position information of the through hole (405) and the reaction cup accommodating station (406) and sending out a judging signal; and

And the control unit is electrically connected with the optocoupler assembly and controls the second rotary driving assembly (402) to act according to the received judging signal, so that the through holes (405) and the reaction cup accommodating stations (406) are in one-to-one correspondence.

9. The sample analysis device according to claim 8, wherein the rotating disk (403) comprises a rotating ring (4031) coaxially provided at intervals on the inner periphery of the reaction disk (404) and a rotating cover plate (4032) provided on the rotating ring (4031), the rotating cover plate (4032) is provided with a cover body, and the incubation module (400) further comprises:

A mounting table (407);

The cleaning and liquid injecting components (408) are at least two groups and are arranged on the mounting table (407) at intervals along the arc, the last cleaning and liquid injecting component (408) is used for sucking residual liquid in the reaction cup (700) in the rotating direction of the rotating cover plate (4032), and the rest cleaning and liquid injecting components (408) are used for sucking the liquid in the reaction cup (700) and injecting cleaning liquid;

and a lifting driving assembly (409) which is installed on the cover body and is used for driving the installation table (407) to lift.

10. The sample analysis device of claim 9, wherein the wash priming assembly (408) comprises:

A guide sleeve movably penetrating the mounting table (407); and a reaction needle integrated in the guide sleeve, wherein the reaction needle is used for sucking liquid in the reaction cup (700) or injecting cleaning liquid into the reaction cup (700), the reaction needle at the tail position comprises a sucking needle (4081) used for sucking the liquid in the reaction cup (700), the rest of the reaction needle comprises a liquid injection needle (4082) used for injecting the cleaning liquid into the reaction cup (700) and a sucking needle (4081) used for sucking the liquid in the reaction cup (700), and the plane of the bottom of the sucking needle (4081) is higher than the plane of the bottom of the liquid injection needle (4082).

11. The sample analysis device of claim 8, wherein the optocoupler assembly comprises:

The plurality of position matching pieces are circumferentially arranged on the rotating disc (403) and correspond to the reaction cup accommodating stations (406) one by one;

the position optical coupler (411) is matched with the position matching piece, acquires the position information of the reaction cup accommodating station (406), and sends out a judging signal according to the position information; and

The reset optocoupler (412) is arranged on the reaction disc (404), a light blocking column is arranged on the rotating disc (403), and the reset optocoupler (412) is matched with the light blocking column to detect whether the rotating disc (403) reaches a reset initial position or not.

12. The sample analysis device of claim 1, wherein the cupped module (300) comprises:

A reaction cup loading bin (301) for holding the reaction cup (700);

The cup sorting rotary drum (302) is provided with a plurality of partition sections (304) at intervals on the inner peripheral wall, the partition sections (304) are obliquely arranged relative to the inner peripheral wall of the cup sorting rotary drum (302), a guide channel (303) is formed between any two adjacent partition sections (304), and the feeding end of the guide channel (303) is communicated with the discharging end of the reaction cup storage bin (301);

The baffle plate (305) is positioned at one side of the cup arranging rotary drum (302) away from the reaction cup charging bin (301), and a cup outlet (308) for discharging the reaction cup (700) is formed in the baffle plate (305);

The first rotary driving assembly (306) is used for driving the cup arranging rotary drum (302) to rotate so as to drive the discharge end of each guide channel (303) to rotate to a position communicated with the cup outlet (308) in sequence; and

The cup pushing mechanism comprises a conveying assembly and a cup pushing assembly (307), wherein the conveying assembly forms a cup falling opening (315) and a second conveying channel (309) communicated with the cup outlet (308), and the cup pushing assembly (307) is used for sequentially pushing the reaction cups (700) in the second conveying channel (309) to the cup falling opening (315); the push cup assembly (307) comprises:

a pusher (3071);

A guide rail (3072) mounted to an outer side wall of the conveyance guide block (310) in a first direction;

A second linear drive (3074) for driving the pusher (3071) in a second direction toward or away from the reaction cup (700) in the cup-falling channel (313), the first direction intersecting the second direction; and

And a first linear driving member (3073) mounted on the guide rail (3072) and used for driving the second linear driving member (3074) to linearly move along a first direction.

13. The sample analysis device according to claim 1, further comprising a cup-dropping module (800), wherein the cup-dropping module (800) is configured to grasp a reaction cup (700) after completion of a reaction in the incubation module (400) and drop the discarded reaction cup (700) to a waste recycling module;

the cup-loss module (800) comprises:

The grabbing mechanism (801) comprises an elastic clamping piece (8011), a lifting plate (8012) and two clamping bodies (8013) which are in sliding connection with the lifting plate (8012), wherein the two clamping bodies (8013) are oppositely arranged and form a clamping groove;

The cup-throwing push block (802), two ends of the elastic clamping piece (8011) are correspondingly connected with two clamping bodies (8013) respectively, idler wheels (8017) used for being in rolling contact with the cup-throwing push block (802) are installed on the clamping bodies (8013), the two clamping bodies (8013) enclose an avoidance groove into which the cup-throwing push block (802) stretches, the idler wheels (8017) are arranged close to the avoidance groove, and the cup-throwing push block (802) is located between the two clamping bodies (8013) and used for being abutted against the two clamping bodies (8013) to enable the two clamping bodies (8013) to slide reversely;

A lifting driving mechanism (803) for driving the lifting plate (8012) to reciprocate between a grabbing position and a cup-throwing position relative to the cup-throwing push block (802);

The reaction cup (700) can extend into the clamping groove at the grabbing position and tension the elastic clamping piece (8011), so that the elastic clamping piece (8011) applies elastic clamping force to the clamping body (8013), the cup-losing push block (802) can squeeze the clamping body (8013) at the cup-losing position, and the two clamping bodies (8013) can slide oppositely and loosen the reaction cup (700) against the elastic clamping force;

And the translation mechanism (804) is used for driving the lifting driving mechanism (803) and the grabbing mechanism (801) to synchronously translate.