技术领域technical field
本实用新型涉及医疗器械技术领域，尤其涉及一种皮下植入式给药装置。The utility model relates to the technical field of medical devices, in particular to a subcutaneous implanted drug delivery device.
背景技术Background technique
皮下植入式给药装置用于体内埋藏导向性区域给药，可以提供重复通道至选定的靶组织或者器官，用于癌症区域化疗、镇痛治疗目的的药物投用和其他疾病的治疗，使药物能直接、反复输送到靶组织或者器官。皮下植入式给药装置比常规静脉或肌肉注射方法能提高局部组织或器官的药液浓度数十倍至百余倍，并长期作用于靶组织，可减轻由于全身性用药引起的不良反应，能够显著提高治疗效果。The subcutaneous implantable drug delivery device is used for implanting guided regional drug delivery in the body, which can provide repeated channels to selected target tissues or organs, and is used for drug administration for cancer regional chemotherapy, analgesic therapy, and other diseases. The drug can be directly and repeatedly delivered to the target tissue or organ. The subcutaneous implantable drug delivery device can increase the concentration of the local tissue or organ by tens to hundreds of times compared with the conventional intravenous or intramuscular injection method, and act on the target tissue for a long time, which can reduce the adverse reactions caused by systemic medication. Can significantly improve the therapeutic effect.
实用新型内容Utility model content
有鉴于此，本实用新型的目的是提供一种皮下植入式给药装置，以解决现有技术中的不足。In view of this, the purpose of this utility model is to provide a subcutaneous implantable drug delivery device to solve the deficiencies in the prior art.
为了达到上述目的，本实用新型的目的是通过下述技术方案实现的：In order to achieve the above object, the purpose of this utility model is achieved through the following technical solutions:
提供一种皮下植入式给药装置，可植入患者皮肤下方，其中，包括储液器和柔性导管，所述储液器为圆形，所述储液器上设有隔膜，所述隔膜面向患者身体的外部，所述柔性导管一端连接所述储液器，另一端远离所述储液器且具有多个侧壁孔，所述柔性导管的内径由近及远依次减小。A subcutaneous implantable drug delivery device is provided, which can be implanted under the patient's skin, wherein it includes a liquid reservoir and a flexible conduit, the liquid reservoir is circular, and a diaphragm is provided on the liquid reservoir, and the diaphragm Facing the outside of the patient's body, one end of the flexible conduit is connected to the liquid reservoir, and the other end is away from the liquid reservoir and has a plurality of sidewall holes, and the inner diameter of the flexible conduit decreases from near to far.
上述皮下植入式给药装置，其中，所述柔性导管包括第一柔性管、连接构件和第二柔性管，所述储液器的一端设有接头，所述储液器通过所述接头连接所述第一柔性管，所述第一柔性管通过所述连接构件连接所述第二柔性管。The above-mentioned subcutaneous implantable drug delivery device, wherein, the flexible catheter includes a first flexible tube, a connecting member and a second flexible tube, and one end of the liquid reservoir is provided with a joint, and the liquid storage tank is connected through the joint The first flexible pipe is connected to the second flexible pipe through the connecting member.
上述皮下植入式给药装置，其中，所述连接构件为短中空管。The subcutaneous implantable drug delivery device above, wherein the connecting member is a short hollow tube.
上述皮下植入式给药装置，其中，还包括夹具，所述夹具用于固定所述第一柔性管和所述接头。The subcutaneous implantable drug delivery device above further includes a clamp, and the clamp is used to fix the first flexible tube and the joint.
上述皮下植入式给药装置，其中，所述侧壁孔的孔径为10μm至0.1mm。The subcutaneous implantable drug delivery device above, wherein the diameter of the side wall hole is 10 μm to 0.1 mm.
上述皮下植入式给药装置，其中，所述储液器采用金属钛制成。The subcutaneous implantable drug delivery device above, wherein the liquid reservoir is made of metal titanium.
与已有技术相比，本实用新型的有益效果在于：Compared with the prior art, the utility model has the beneficial effects of:
可周期性地和重复地装药，可由医生监测患者并根据患者可能继续经历的疼痛量或患者对药物的耐受性，增加或减少装入装置的药物量，可永久性皮下植入，无菌性强，安全性高，结构简单，操作方便，成本低廉。Can be filled periodically and repeatedly, allows the patient to be monitored by a physician and the amount of drug loaded into the device can be increased or decreased based on the amount of pain the patient is likely to continue to experience or the patient's tolerance to the drug, can be permanently implanted subcutaneously, without The utility model has the advantages of strong antibacterial property, high safety, simple structure, convenient operation and low cost.
附图说明Description of drawings
构成本实用新型的一部分的附图用来提供对本实用新型的进一步理解，本实用新型的示意性实施例及其说明用于解释本实用新型，并不构成对本实用新型的不当限定。在附图中：The accompanying drawings constituting a part of the utility model are used to provide a further understanding of the utility model, and the schematic embodiments of the utility model and their descriptions are used to explain the utility model, and do not constitute improper limitations to the utility model. In the attached picture:
图1示出了本实用新型皮下植入式给药装置的结构示意图；Fig. 1 shows the structural representation of the subcutaneous implantable drug delivery device of the present invention;
图2示出了本实用新型皮下植入式给药装置的结构分解图；Fig. 2 shows an exploded view of the structure of the subcutaneous implantable drug delivery device of the present invention;
图3示出了本实用新型皮下植入式给药装置的使用状态图。Fig. 3 shows a diagram of the use status of the subcutaneous implantable drug delivery device of the present invention.
具体实施方式Detailed ways
下面将结合本实用新型实施例中的附图，对本实用新型实施例中的技术方案进行清楚、完整地描述，显然，所描述的实施例仅仅是本实用新型一部分实施例，而不是全部的实施例。基于本实用新型中的实施例，本领域普通技术人员在没有作出创造性劳动前提下所获得的所有其他实施例，都属于本实用新型保护的范围。The technical solutions in the embodiments of the present invention will be clearly and completely described below in conjunction with the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of them. example. Based on the embodiments of the present utility model, all other embodiments obtained by persons of ordinary skill in the art without making creative efforts belong to the scope of protection of the present utility model.
需要说明的是，在不冲突的情况下，本实用新型中的实施例及实施例中的特征可以相互组合。It should be noted that, in the case of no conflict, the embodiments of the present invention and the features in the embodiments can be combined with each other.
参考图1、图2所示，本实用新型皮下植入式给药装置可植入患者皮肤下方，包括储液器1和柔性导管2，柔性导管2用于将药物输送到期望的神经等组织内，储液器1为圆形，储液器1上设有隔膜3，隔膜3面向患者身体的外部，柔性导管2一端连接储液器1，另一端远离储液器1且具有多个供药液缓慢渗出的侧壁孔4，柔性导管2的内径由近及远依次减小。本技术方案中，柔性导管2包括第一柔性管21、连接构件22和第二柔性管23，储液器1的一端设有接头11，储液器1通过接头11连接第一柔性管21，第一柔性管21通过连接构件22连接第二柔性管23。连接构件22为短中空管。本装置还包括夹具5，夹具5用于固定第一柔性管21和接头11。第一柔性管21和第二柔性管23的管直径可以为约0.10mm至约6.00mm，侧壁孔4的孔径为10μm至0.1mm。储液器1的合适体积可以为约0.5mL至约25mL，储液器1可由任何合适的材料制成，例如聚合物材料或非铁金属，但钛可能是特别优选的，因为钛可有助于减少感染。Referring to Fig. 1 and Fig. 2, the subcutaneous implantable drug delivery device of the present invention can be implanted under the patient's skin, including a liquid reservoir 1 and a flexible catheter 2, and the flexible catheter 2 is used to deliver drugs to desired nerves and other tissues Inside, the liquid reservoir 1 is circular, and the liquid reservoir 1 is provided with a diaphragm 3 facing the outside of the patient's body. One end of the flexible conduit 2 is connected to the liquid reservoir 1, and the other end is far away from the liquid reservoir 1 and has multiple The side wall hole 4 through which the medicinal liquid slowly seeps out, and the inner diameter of the flexible catheter 2 decreases successively from near to far. In this technical solution, the flexible conduit 2 includes a first flexible pipe 21, a connecting member 22 and a second flexible pipe 23, and one end of the liquid reservoir 1 is provided with a joint 11, and the liquid reservoir 1 is connected to the first flexible pipe 21 through the joint 11, The first flexible pipe 21 is connected to the second flexible pipe 23 through the connection member 22 . The connection member 22 is a short hollow tube. The device also includes a clamp 5 for fixing the first flexible pipe 21 and the joint 11 . The tube diameter of the first flexible tube 21 and the second flexible tube 23 may be about 0.10 mm to about 6.00 mm, and the diameter of the side wall hole 4 is 10 μm to 0.1 mm. A suitable volume for the reservoir 1 may be from about 0.5 mL to about 25 mL, and the reservoir 1 may be made of any suitable material, such as a polymeric material or a non-ferrous metal, but titanium may be particularly preferred because it may help to reduce infection.
可以使用开放式或侵入性手术方法植入本装置，在替代实施例中，还可以通过非侵入性外科手术方法植入本装置，例如，可以使用荧光镜或CT引导植入装置以进行放置。参看图3所示，储液器1设置在皮肤6下方，隔膜3面向患者身体的外部，柔性导管2可以设置在皮肤6下方并且在任何肌肉或骨头组织上方，通过用与药物源流体流动连通的套管7刺穿皮肤6和隔膜3，可以给储液器1充液，使得当药物施加流体流动压力时，药物通过套管7进入储液器1。在移除套管7之后，隔膜3可以防止药物或盐水回流到进入部位附近的组织中。在一个实施例中，套管7可以是填充有药物并具有皮下注射针头的注射器。在另一个实施例中，套管7可以可拆卸地连接到药物源8。The device can be implanted using open or invasive surgical methods, and in alternative embodiments, the device can also be implanted by non-invasive surgical methods, for example, fluoroscopy or CT can be used to guide the implant for placement. Referring to Fig. 3, the reservoir 1 is placed under the skin 6, the diaphragm 3 faces the outside of the patient's body, the flexible conduit 2 can be placed under the skin 6 and above any muscle or bone tissue, and is in fluid flow communication with a drug source. The cannula 7 pierces the skin 6 and the septum 3, and can fill the liquid reservoir 1, so that when the medicine exerts fluid flow pressure, the medicine enters the liquid reservoir 1 through the cannula 7. After removal of the cannula 7, the septum 3 prevents backflow of the drug or saline into the tissue near the entry site. In one embodiment, the cannula 7 may be a syringe filled with a drug and having a hypodermic needle. In another embodiment, the cannula 7 can be detachably connected to the drug source 8 .
从上述实施例可以看出，本实用新型的优势在于：As can be seen from the foregoing embodiments, the utility model has the advantages of:
可周期性地和重复地装药，可由医生监测患者并根据患者可能继续经历的疼痛量或患者对药物的耐受性，增加或减少装入装置的药物量，可永久性皮下植入，无菌性强，安全性高，结构简单，操作方便，成本低廉。Can be filled periodically and repeatedly, allows the patient to be monitored by a physician and the amount of drug loaded into the device can be increased or decreased based on the amount of pain the patient is likely to continue to experience or the patient's tolerance to the drug, can be permanently implanted subcutaneously, without The utility model has the advantages of strong antibacterial property, high safety, simple structure, convenient operation and low cost.
以上对本实用新型的具体实施例进行了详细描述，但本实用新型并不限制于以上描述的具体实施例，其只是作为范例。对于本领域技术人员而言，任何等同修改和替代也都在本实用新型的范畴之中。因此，在不脱离本实用新型的精神和范围下所作出的均等变换和修改，都应涵盖在本实用新型的范围内。The specific embodiments of the present invention have been described in detail above, but the present invention is not limited to the specific embodiments described above, which are only examples. For those skilled in the art, any equivalent modifications and substitutions are also within the scope of the present utility model. Therefore, all equivalent transformations and modifications made without departing from the spirit and scope of the present invention shall fall within the scope of the present invention.
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201821322230.XUCN209630432U (en) | 2018-08-16 | 2018-08-16 | A subcutaneous implantable drug delivery device |
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201821322230.XUCN209630432U (en) | 2018-08-16 | 2018-08-16 | A subcutaneous implantable drug delivery device |
| Publication Number | Publication Date |
|---|---|
| CN209630432Utrue CN209630432U (en) | 2019-11-15 |
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201821322230.XUExpired - Fee RelatedCN209630432U (en) | 2018-08-16 | 2018-08-16 | A subcutaneous implantable drug delivery device |
| Country | Link |
|---|---|
| CN (1) | CN209630432U (en) |
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116035800A (en)* | 2023-04-03 | 2023-05-02 | 首都医科大学附属北京友谊医院 | A subcutaneous implantable repeat drug delivery device through the semicircular canal inner ear |
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116035800A (en)* | 2023-04-03 | 2023-05-02 | 首都医科大学附属北京友谊医院 | A subcutaneous implantable repeat drug delivery device through the semicircular canal inner ear |
| CN116035800B (en)* | 2023-04-03 | 2023-10-31 | 首都医科大学附属北京友谊医院 | A subcutaneous implantable transsemicircular canal inner ear repeated drug delivery device |
| Publication | Publication Date | Title |
|---|---|---|
| US20210268181A1 (en) | Sprinkler cannula | |
| JP4604022B2 (en) | Portable device for the administration of fluids to tissues and tumors by a delivery-enhanced delivery method | |
| US8105310B2 (en) | Infiltration cannula | |
| AU764894B2 (en) | Implantable device for access to a treatment site | |
| US6893429B2 (en) | Convection enhanced delivery catheter to treat brain and other tumors | |
| US6974448B2 (en) | Method for convection enhanced delivery catheter to treat brain and other tumors | |
| US20040236313A1 (en) | Infiltration cannula | |
| KR101405610B1 (en) | Medicinal fluid injection port for implanting skull | |
| CN209771078U (en) | drug delivery device | |
| US10188421B2 (en) | Methods for placing a sympathetic block, catheters, catheter assemblies and related methods | |
| CN111330137A (en) | Drug delivery device | |
| CN209630432U (en) | A subcutaneous implantable drug delivery device | |
| CN111588940A (en) | Implanted infusion port and using method | |
| CN102151346A (en) | Hypodermic implantation type medicine feeder | |
| US20220134076A1 (en) | Implantable medical device for delivery of pharmacological agents to the deep brain structures | |
| CN112791267A (en) | an infusion port | |
| JP2002500072A (en) | Method and apparatus for disinfecting a subcutaneous implant device | |
| CN216725412U (en) | Transfusion port | |
| US20070073239A1 (en) | Catheter device | |
| CN202061177U (en) | Hypodermic implantation type drug administration device | |
| CN200998472Y (en) | Postoperative regional anesthesia analgesia bag | |
| CN112569457B (en) | Continuous administration cyst tube system | |
| CN217793261U (en) | Continuous drug administration device in superficial solid tumor | |
| CN219231114U (en) | Microcatheter for topical administration and medical device comprising same | |
| CN214550516U (en) | An implantable intraperitoneal subcutaneous chemotherapy device |
| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee | Granted publication date:20191115 | |
| CF01 | Termination of patent right due to non-payment of annual fee |