技术领域technical field
本实用新型涉及椎间融合器，尤其涉及一种可探测的椎间融合器。The utility model relates to an intervertebral fusion device, in particular to a detectable intervertebral fusion device.
背景技术Background technique
脊拄融合术最初由Hibbs等在1911年报道，之后Mercer于1936年提出椎体间融合的理论后，脊柱融合手术得到了很快的发展，20世纪80年代开始应用椎间融合器加植骨融合治疗下腰痛并取得了很好的疗效。从此，脊柱融合术从单纯的植骨技术发展到了融合器融合。Spinal fusion was first reported by Hibbs et al. in 1911. After Mercer proposed the theory of intervertebral fusion in 1936, spinal fusion surgery developed rapidly. In the 1980s, intervertebral fusion and bone grafting began to be applied. Fusion treatment of low back pain and achieved good results. Since then, spinal fusion has developed from simple bone grafting to cage fusion.
脊柱融合术是目前临床上最常用的手术方式之一，是治疗脊柱结核、感染、畸形、退行性病变以及椎间盘损伤等脊柱疾患的有效手段。它主要通过在椎间隙植入椎间融合器，同时植入大量的自体骨或同种异体骨，从而实现椎体间融合，达到稳定脊柱的目的。Spinal fusion is one of the most commonly used surgical methods in clinical practice, and it is an effective means to treat spinal diseases such as spinal tuberculosis, infection, deformity, degenerative disease and intervertebral disc injury. It mainly achieves intervertebral fusion and stabilizes the spine by implanting an intervertebral fusion device in the intervertebral space and implanting a large amount of autologous bone or allogeneic bone at the same time.
目前的脊柱融合器植入椎间隙主要起支撑作用，不能诱导成骨，因此往往需要在融合器中植入自体骨或同种异体骨，以达到骨性融合的目的，自体骨需要从患者的身体内取出，往往会给患者身心带来很大的痛苦，而同种异体骨不但价格昂贵，而且融合效果也不理想，经常出现腰椎术后假关节形成等腰椎不融合的情况，此外在X光检查时，难以定位。The current spinal fusion device implanted in the intervertebral space mainly plays a supporting role and cannot induce osteogenesis. Therefore, it is often necessary to implant autologous bone or allogeneic bone in the fusion device to achieve the purpose of bony fusion. The autologous bone needs to be obtained from the patient's Taking it out of the body often brings a lot of pain to the patient physically and mentally, and the allogeneic bone is not only expensive, but also the fusion effect is not ideal, and lumbar disfusion often occurs such as pseudarthrosis after lumbar surgery. In addition, in X Difficult to locate when inspected by light.
羟基磷灰石(Hydroxyapatite,HA)被认为是目前生物相容性最好的生物陶瓷之一，这主要是由于HA与人体骨组织中的无机成分相似，植入人体后在短期内能与骨骼形成骨性结合并具有诱导成骨作用，因此在临床上被广泛作为生物活性涂层材料，但是到目前为止，还没有关于羟基磷灰石涂层融合器的报道。Hydroxyapatite (Hydroxyapatite, HA) is considered to be one of the best biocompatible bioceramics at present, mainly because HA is similar to the inorganic components in human bone tissue, and it can be combined with bone in a short period of time after being implanted in the human body. Forms osseointegration and induces osteogenesis, so it is widely used as a bioactive coating material clinically, but so far, there is no report on hydroxyapatite-coated cages.
实用新型内容Utility model content
本实用新型的目的是在于提供一种可探测的椎间融合器，解决上述现有技术问题中的一个或者多个。The purpose of this utility model is to provide a detectable intervertebral fusion device to solve one or more of the above-mentioned problems in the prior art.
根据本实用新型的一个方面，提供一种可探测的椎间融合器，包括方柱形的融合器本体，融合器本体的一对相背的表面均设有多孔结构，融合器本体的内部设有三维多孔骨组织工程支架结构，融合器本体表面涂有羟基磷灰石涂层，多孔结构和三维多孔骨组织工程支架结构相互连通，与多孔结构所在的表面相垂直的棱设有倒齿；融合器本体设有贯穿孔，贯穿孔内设有金属棒。According to one aspect of the present invention, a detectable intervertebral fusion device is provided, which includes a square column-shaped fusion device body, a pair of opposite surfaces of the fusion device body are provided with porous structures, and the interior of the fusion device body is provided with There is a three-dimensional porous bone tissue engineering scaffold structure, the surface of the cage body is coated with hydroxyapatite coating, the porous structure and the three-dimensional porous bone tissue engineering scaffold structure are connected to each other, and the ribs perpendicular to the surface where the porous structure is located are provided with inverted teeth; The fuser body is provided with a through hole, and a metal rod is arranged in the through hole.
在一些实施方式中，三维多孔骨组织工程支架结构的孔隙率为67％。由此，能较好的适应细胞生长、营养流的输送与代谢产物的排出。In some embodiments, the porosity of the three-dimensional porous bone tissue engineering scaffold structure is 67%. Therefore, it can better adapt to cell growth, delivery of nutrient flow and discharge of metabolites.
本实用新型通过融合器表面羟基磷灰石涂层和内部三维多孔骨组织工程支架结构的诱导作用，融合器与骨组织间通过“生长”成为一体，不但克服了现有技术中需要大量植骨缺点，而且融合器与周围骨组织通过“生长”成为一体，有效避免了脊柱融合术后不融合或假关节形成等并发症的发生，具有很好的临床使用效果。此外，在棱上设置有倒齿，能稳定地设置在椎间，不会出现沉降的现象；且其中设置有贯穿孔，贯穿孔内设置有金属棒，可以在X光检查时定位准确。Through the inductive effect of the hydroxyapatite coating on the surface of the cage and the internal three-dimensional porous bone tissue engineering scaffold structure, the utility model integrates the cage and the bone tissue through "growth", which not only overcomes the need for a large number of bone grafts in the prior art In addition, the cage and the surrounding bone tissue become one through "growth", which effectively avoids the occurrence of complications such as non-fusion or pseudarthrosis after spinal fusion, and has a good clinical application effect. In addition, there are inverted teeth on the ribs, which can be stably placed between the vertebrae without subsidence; and there are through holes, and metal rods are arranged in the through holes, which can be accurately positioned during X-ray inspection.
附图说明Description of drawings
图1是本实用新型一种可探测的椎间融合器的结构示意图。Fig. 1 is a schematic structural diagram of a detectable intervertebral fusion device of the present invention.
具体实施方式Detailed ways
下面结合附图说明，对本实用新型作进一步详细说明。Below in conjunction with accompanying drawing description, the utility model is described in further detail.
如图1所示，一种可探测的椎间融合器，包括方柱形的融合器本体1，融合器本体1的一对相背的表面均开设有多孔结构2，具体来说融合器本体1的一个面开设有多孔结构2，另一个与之相背的面也开设有多孔结构2。多孔结构2为不规则的孔。融合器本体1的内部一体成型有三维多孔骨组织工程支架结构3，三维多孔骨组织工程支架结构3内部有相连通的高孔隙率多孔结构，能适应细胞生长、营养流的输送与代谢产物的排出，本实施例中，三维多孔骨组织工程支架结构3的孔隙率为67％，由此能较好的适应细胞生长、营养流的输送与代谢产物的排出。融合器本体1表面涂有羟基磷灰石涂层4，在本实施例中，在融合器本体1设有多孔结构2的表面涂有羟基磷灰石涂层4。多孔结构2和三维多孔骨组织工程支架结构3相互连通，融合器本体1一表面的多孔结构2通过三维多孔骨组织工程支架结构3与融合器本体1另一表面的多孔结构2相连通。此外，与多孔结构2所在的表面相垂直的融合器本体1的棱一体成型有倒齿5，倒齿5呈锯齿状，且以与多孔结构2所在的表面相垂直的直线排列，由此，能稳定地设置在椎间，不会出现沉降的现象。融合器本体1设有贯穿孔6，贯穿孔6内插设有金属棒7，可以在X光检查时定位准确。As shown in Figure 1, a detectable intervertebral fusion device includes a square column-shaped fusion device body 1, and a pair of opposite surfaces of the fusion device body 1 are provided with porous structures 2, specifically, the fusion device body One surface of 1 is provided with porous structure 2, and the other surface opposite to it is also provided with porous structure 2. The porous structure 2 is irregular pores. The inside of the cage body 1 is integrally formed with a three-dimensional porous bone tissue engineering scaffold structure 3, and the three-dimensional porous bone tissue engineering scaffold structure 3 has a connected high-porosity porous structure inside, which can adapt to cell growth, nutrient flow delivery and metabolite production. Exhaust. In this embodiment, the porosity of the three-dimensional porous bone tissue engineering scaffold structure 3 is 67%, which can better adapt to cell growth, delivery of nutrient flow and discharge of metabolites. The surface of the cage body 1 is coated with a hydroxyapatite coating 4 , and in this embodiment, the surface of the cage body 1 provided with a porous structure 2 is coated with a hydroxyapatite coating 4 . The porous structure 2 and the three-dimensional porous bone tissue engineering scaffold structure 3 communicate with each other, and the porous structure 2 on one surface of the cage body 1 communicates with the porous structure 2 on the other surface of the cage body 1 through the three-dimensional porous bone tissue engineering scaffold structure 3 . In addition, the edge of the cage body 1 perpendicular to the surface where the porous structure 2 is located is integrally formed with inverted teeth 5, which are in a zigzag shape and arranged in a straight line perpendicular to the surface where the porous structure 2 is located, thus, It can be stably set between the vertebrae without subsidence. The fuser body 1 is provided with a through hole 6, and a metal rod 7 is inserted in the through hole 6, which can be accurately positioned during X-ray inspection.
综上所述，本实用新型通过融合器表面羟基磷灰石涂层和内部三维多孔骨组织工程支架结构的诱导作用，融合器与骨组织间通过“生长”成为一体，不但克服了现有技术中需要大量植骨缺点，而且融合器与周围骨组织通过“生长”成为一体，有效避免了脊柱融合术后不融合或假关节形成等并发症的发生，具有很好的临床使用效果。此外，在棱上设置有倒齿，能稳定地设置在椎间，不会出现沉降的现象，其中设置有贯穿孔，贯穿孔内设置有金属棒，可以在X光检查时定位准确。In summary, the utility model through the inductive effect of the hydroxyapatite coating on the surface of the fusion device and the internal three-dimensional porous bone tissue engineering scaffold structure, the fusion device and the bone tissue are integrated through "growth", which not only overcomes the existing technology The disadvantage of needing a large number of bone grafts, and the integration of the fusion cage and the surrounding bone tissue through "growth", effectively avoids the occurrence of complications such as non-fusion or pseudarthrosis after spinal fusion, and has a good clinical application effect. In addition, there are inverted teeth on the ribs, which can be stably placed between the vertebrae without subsidence. There are through holes, and metal rods are arranged in the through holes, which can be accurately positioned during X-ray inspection.
以上所述仅是本实用新型的一种实施方式，应当指出，对于本领域普通技术人员来说，在不脱离本实用新型创造构思的前提下，还可以做出若干相似的变形和改进，这些也应视为本实用新型的保护范围之内。The above description is only one embodiment of the present utility model, and it should be pointed out that those skilled in the art can make several similar deformations and improvements without departing from the inventive concept of the present utility model. It should also be considered within the protection scope of the present utility model.
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201520171603.8UCN204501117U (en) | 2015-03-25 | 2015-03-25 | A kind of detectable Invasive lumbar fusion device |
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201520171603.8UCN204501117U (en) | 2015-03-25 | 2015-03-25 | A kind of detectable Invasive lumbar fusion device |
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| CN204501117Utrue CN204501117U (en) | 2015-07-29 |
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| CN201520171603.8UExpired - Fee RelatedCN204501117U (en) | 2015-03-25 | 2015-03-25 | A kind of detectable Invasive lumbar fusion device |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN106729977A (en)* | 2017-01-12 | 2017-05-31 | 上海锐植医疗器械有限公司 | A kind of bioactivity Invasive lumbar fusion device |
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN106729977A (en)* | 2017-01-12 | 2017-05-31 | 上海锐植医疗器械有限公司 | A kind of bioactivity Invasive lumbar fusion device |
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