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CN202589509U - Blood pressure and blood oxygen saturation degree simultaneous detection device - Google Patents

Blood pressure and blood oxygen saturation degree simultaneous detection device
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CN202589509U
CN202589509UCN 201220302283CN201220302283UCN202589509UCN 202589509 UCN202589509 UCN 202589509UCN 201220302283CN201220302283CN 201220302283CN 201220302283 UCN201220302283 UCN 201220302283UCN 202589509 UCN202589509 UCN 202589509U
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宋义林
高树枚
彭景云
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Heilongjiang University
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Translated fromChinese

血压与血氧饱和度的同时检测装置,属于桡骨动脉检测技术领域。它解决了现有血压与血氧饱和度的检测需要分别采用单独的传感器来实现,造成检测装置的电子元件多及结构复杂的问题。装置包括袖带,它还包括脉冲发生器、光电容积传感器、波峰保持器、第一高通滤波器、第一低通滤波器、第二高通滤波器、第二低通滤波器、A/D转换器、D/A转换器、计算机、电空变换器、气泵、功率放大器和压力传感器;它以桡骨动脉为检测对象,能够实现对血压与动、静脉血的血氧饱和度进行同时检测,它实现了对静脉血的血氧饱和度的间接测量。本实用新型适用于血压与血氧饱和度的同时检测。

Figure 201220302283

A simultaneous detection device for blood pressure and blood oxygen saturation belongs to the technical field of radial artery detection. It solves the problem that the existing detection of blood pressure and blood oxygen saturation needs to be realized by using separate sensors respectively, resulting in many electronic components and complicated structure of the detection device. The device includes a cuff, which also includes a pulse generator, a photocapacitance sensor, a peak hold, a first high-pass filter, a first low-pass filter, a second high-pass filter, a second low-pass filter, an A/D conversion device, D/A converter, computer, electropneumatic converter, air pump, power amplifier and pressure sensor; it takes the radial artery as the detection object, and can realize simultaneous detection of blood pressure and blood oxygen saturation of arterial and venous blood. The indirect measurement of oxygen saturation of venous blood is realized. The utility model is suitable for simultaneous detection of blood pressure and blood oxygen saturation.

Figure 201220302283

Description

Translated fromChinese
血压与血氧饱和度的同时检测装置Simultaneous detection device for blood pressure and blood oxygen saturation

技术领域technical field

本实用新型涉及一种血压与血氧饱和度的同时检测装置,属于桡骨动脉检测技术领域。The utility model relates to a simultaneous detection device for blood pressure and blood oxygen saturation, which belongs to the technical field of radial artery detection.

背景技术Background technique

目前,在临床或日常健康检测时的血压间接测量方法有多种。例如,传统的以上臂肱动脉为检测对象的基于柯氏法的水银式血压计血压测量方法;以手腕处的桡骨动脉为检测对象的基于压力示波法的电子血压计血压测量方法,以及基于容积振动法的电子血压计血压测量方法;以指动脉为检测对象的基于容积振动法的电子血压计血压测量方法等。而对于血氧饱和度的间接测量方法通常是以指动脉为检测对象,采用双波长分光法进行动脉血的血氧饱和度测量。在使用上述方法对血压和血氧饱和度进行测量时,血压的测量需要单独的血压计,血氧饱和度的测量也需要单独的血氧饱和度检测仪。即便是使用多功能检测仪来同时测量血压与血氧饱和度,其内部的测量过程还是分别采用单独的光电传感器来实现的,两者不能兼用。这样,就造成了检测装置的电子元件多及结构复杂等问题;同时,这种方法也不能实现对静脉血的血氧饱和度的间接测量。At present, there are many indirect blood pressure measurement methods in clinical or daily health checks. For example, the traditional Korotkoff-based mercury sphygmomanometer blood pressure measurement method based on the brachial artery of the upper arm; the electronic sphygmomanometer blood pressure measurement method based on the pressure oscillometric method based on the radial artery at the wrist as the detection object; Electronic sphygmomanometer blood pressure measurement method based on volume vibration method; electronic sphygmomanometer blood pressure measurement method based on volume vibration method with finger artery as the detection object, etc. For the indirect measurement method of blood oxygen saturation, finger arteries are usually used as the detection object, and the blood oxygen saturation of arterial blood is measured by dual-wavelength spectrometry. When the above method is used to measure blood pressure and blood oxygen saturation, the blood pressure measurement requires a separate sphygmomanometer, and the blood oxygen saturation measurement also requires a separate blood oxygen saturation detector. Even if a multi-function detector is used to measure blood pressure and blood oxygen saturation at the same time, the internal measurement process is realized by a separate photoelectric sensor, and the two cannot be used together. In this way, problems such as a large number of electronic components and a complex structure of the detection device are caused; meanwhile, this method cannot realize the indirect measurement of the blood oxygen saturation of venous blood.

发明内容Contents of the invention

本实用新型是为了解决现有血压与血氧饱和度的检测需要分别采用单独的传感器来实现,造成检测装置的电子元件多及结构复杂的问题,提供一种血压与血氧饱和度的同时检测装置。The utility model is to solve the problem that the existing detection of blood pressure and blood oxygen saturation needs to be realized by using separate sensors, which causes many electronic components and complex structure of the detection device, and provides a simultaneous detection of blood pressure and blood oxygen saturation device.

本实用新型所述血压与血氧饱和度的同时检测装置,它包括袖带,它还包括脉冲发生器、光电容积传感器、波峰保持器、第一高通滤波器、第一低通滤波器、第二高通滤波器、第二低通滤波器、A/D转换器、D/A转换器、计算机、电空变换器、气泵、功率放大器和压力传感器,The simultaneous detection device of blood pressure and blood oxygen saturation described in the utility model includes a cuff, and it also includes a pulse generator, a photoelectric volume sensor, a peak holder, a first high-pass filter, a first low-pass filter, a second Second high-pass filter, second low-pass filter, A/D converter, D/A converter, computer, electro-pneumatic converter, air pump, power amplifier and pressure sensor,

气泵通过管路为袖带供气,电空变换器设置在气泵与袖带之间的管路上,电空变换器的控制信号输入端连接功率放大器的控制信号输出端,功率放大器的控制信号输入端连接D/A转换器的模拟信号输出端,D/A转换器的数字信号输入端连接计算机的控制信号输出端;The air pump supplies air to the cuff through the pipeline. The electropneumatic converter is arranged on the pipeline between the air pump and the cuff. The control signal input end of the electropneumatic converter is connected to the control signal output end of the power amplifier, and the control signal input end of the power amplifier is Connect the analog signal output end of the D/A converter, and the digital signal input end of the D/A converter is connected to the control signal output end of the computer;

压力传感器的压力采集端通过管路与电空变换器和袖带之间的管路连通,压力传感器的压力信号输出端连接A/D转换器的压力信号输入端;The pressure acquisition end of the pressure sensor communicates with the pipeline between the electropneumatic converter and the cuff through the pipeline, and the pressure signal output end of the pressure sensor is connected to the pressure signal input end of the A/D converter;

光电容积传感器设置于袖带内,光电容积传感器由第一波长发光二极管、第二波长发光二极管和光电二极管组成,脉冲发生器的第一脉冲信号输出端连接第一波长发光二极管的脉冲信号输入端,脉冲发生器的第二脉冲信号输出端连接第二波长发光二极管的脉冲信号输入端,脉冲发生器的第三脉冲信号输出端连接光电二极管的第一驱动信号输入端,脉冲发生器的第四脉冲信号输出端连接光电二极管的第二驱动信号输入端,脉冲发生器的第一脉冲信号和第三脉冲信号同时导通或关闭,脉冲发生器的第二脉冲信号和第四脉冲信号同时关闭或导通,光电二极管分别用于采集第一波长发光二极管和第二波长发光二极管的光电容积信号,光电二极管的采集信号输出端连接波峰保持器的采集信号输入端,波峰保持器的对应于第一波长发光二极管的波长信号输出端同时连接第一高通滤波器的光波信号输入端和第一低通滤波器和光波信号输入端,第一高通滤波器的光波信号输出端连接A/D转换器的第一模拟信号输入端,第一低通滤波器的光波信号输出端连接A/D转换器的第二模拟信号输入端,波峰保持器的对应于第二波长发光二极管的波长信号输出端同时连接第二高通滤波器的光波信号输入端和第二低通滤波器和光波信号输入端,第二高通滤波器的光波信号输出端连接A/D转换器的第三模拟信号输入端,第二低通滤波器的光波信号输出端连接A/D转换器的第四模拟信号输入端,A/D转换器的数字信号输出端连接计算机的采集信号输入端。The photocapacitive volumetric sensor is arranged in the cuff, and the photocapacitive volumetric sensor is composed of a first-wavelength light-emitting diode, a second-wavelength light-emitting diode and a photodiode, and the first pulse signal output end of the pulse generator is connected to the pulse signal input end of the first-wavelength light-emitting diode , the second pulse signal output end of the pulse generator is connected to the pulse signal input end of the second wavelength light-emitting diode, the third pulse signal output end of the pulse generator is connected to the first drive signal input end of the photodiode, and the fourth pulse signal output end of the pulse generator is The pulse signal output end is connected to the second drive signal input end of the photodiode, the first pulse signal and the third pulse signal of the pulse generator are turned on or off at the same time, the second pulse signal and the fourth pulse signal of the pulse generator are turned off or off at the same time conduction, the photodiodes are respectively used to collect the photocapacitance signals of the light-emitting diodes of the first wavelength and the light-emitting diodes of the second wavelength, the collection signal output terminals of the photodiodes are connected to the collection signal input terminals of the peak holder, and the peak holder corresponds to the first The wavelength signal output end of the wavelength light-emitting diode is connected to the light wave signal input end of the first high-pass filter and the first low-pass filter and the light wave signal input end at the same time, and the light wave signal output end of the first high-pass filter is connected to the A/D converter The first analog signal input end, the light wave signal output end of the first low-pass filter is connected to the second analog signal input end of the A/D converter, and the wavelength signal output end corresponding to the second wavelength light-emitting diode of the wave peak holder is connected simultaneously The light-wave signal input end of the second high-pass filter and the second low-pass filter and the light-wave signal input end, the light-wave signal output end of the second high-pass filter are connected to the third analog signal input end of the A/D converter, the second low-pass filter The light wave signal output end of the pass filter is connected to the fourth analog signal input end of the A/D converter, and the digital signal output end of the A/D converter is connected to the acquisition signal input end of the computer.

第一波长发光二极管的发光波长为940nm,第二波长发光二极管的发光波长为805nm,光电二极管的感光波长中心范围为805nm至940nm。The light-emitting wavelength of the light-emitting diode with the first wavelength is 940nm, the light-emitting wavelength of the light-emitting diode with the second wavelength is 805nm, and the photosensitive wavelength center range of the photodiode is from 805nm to 940nm.

脉冲发生器的驱动频率为500Hz。The driving frequency of the pulse generator is 500 Hz.

所述脉冲发生器的第一脉冲信号和第二脉冲信号的关系为:在脉冲发生器脉冲信号的一个循环周期内,第一脉冲信号和第二脉冲信号的导通时间各为1/3周期,第一脉冲信号和第二脉冲信号交替导通或关闭的时间差为1/6周期。The relationship between the first pulse signal and the second pulse signal of the pulse generator is: in one cycle period of the pulse generator pulse signal, the conduction time of the first pulse signal and the second pulse signal is 1/3 cycle respectively , the time difference between the first pulse signal and the second pulse signal being turned on or off alternately is 1/6 cycle.

本实用新型的优点是:本实用新型在使用中以桡骨动脉为检测对象,能够实现对血压与动、静脉血的血氧饱和度进行同时检测,它实现了对静脉血的血氧饱和度的间接测量。本实用新型可使用在血氧饱和度较低和末梢循环很差的情况下,检测的精度高,实现了静脉血氧饱和度无创性检测,提高了检测稳定性,简化了结构,降低了成本,并可实现装置的小型化。The utility model has the advantages that: in use, the utility model takes the radial artery as the detection object, and can simultaneously detect the blood pressure and the blood oxygen saturation of the arterial and venous blood, and it realizes the detection of the blood oxygen saturation of the venous blood. indirect measurement. The utility model can be used in the case of low blood oxygen saturation and poor peripheral circulation, and has high detection accuracy, realizes non-invasive detection of venous blood oxygen saturation, improves detection stability, simplifies structure, and reduces cost , and can realize the miniaturization of the device.

附图说明Description of drawings

图1为本实用新型装置的电气原理框图;Fig. 1 is the electrical principle block diagram of the utility model device;

图2为本实用新型的检测原理图;Fig. 2 is the detection schematic diagram of the utility model;

图3为对应于图2的吸光度曲线图;Fig. 3 is the absorbance graph corresponding to Fig. 2;

图4为还原血红蛋白Hb与氧合血红蛋白Hbo对红光与红外光的吸收曲线图。Fig. 4 is a graph showing absorption curves of reduced hemoglobin Hb and oxyhemoglobin Hbo to red light and infrared light.

具体实施方式Detailed ways

具体实施方式一:下面结合图1说明本实施方式,本实施方式所述血压与血氧饱和度的同时检测装置,它包括袖带1,它还包括脉冲发生器2、光电容积传感器3、波峰保持器4、第一高通滤波器5-1、第一低通滤波器5-2、第二高通滤波器5-3、第二低通滤波器5-4、A/D转换器6、D/A转换器7、计算机8、电空变换器9、气泵10、功率放大器11和压力传感器12,Specific embodiment one: the present embodiment is described below in conjunction with Fig. 1, the simultaneous detection device of blood pressure and blood oxygen saturation described in the present embodiment, it comprisescuff 1, and it also comprisespulse generator 2,photoelectric volume sensor 3,peak Holder 4, first high-pass filter 5-1, first low-pass filter 5-2, second high-pass filter 5-3, second low-pass filter 5-4, A/D converter 6, D /A converter 7,computer 8,electropneumatic converter 9,air pump 10,power amplifier 11 andpressure sensor 12,

气泵10通过管路为袖带1供气,电空变换器9设置在气泵10与袖带1之间的管路上,电空变换器9的控制信号输入端连接功率放大器11的控制信号输出端,功率放大器11的控制信号输入端连接D/A转换器7的模拟信号输出端,D/A转换器7的数字信号输入端连接计算机8的控制信号输出端;Theair pump 10 supplies air to thecuff 1 through the pipeline, the electro-pneumatic converter 9 is arranged on the pipeline between theair pump 10 and thecuff 1, and the control signal input end of the electro-pneumatic converter 9 is connected to the control signal output end of thepower amplifier 11 , the control signal input end of thepower amplifier 11 is connected to the analog signal output end of the D/A converter 7, and the digital signal input end of the D/A converter 7 is connected to the control signal output end of thecomputer 8;

压力传感器12的压力采集端通过管路与电空变换器9和袖带1之间的管路连通,压力传感器12的压力信号输出端连接A/D转换器6的压力信号输入端;The pressure acquisition end of thepressure sensor 12 communicates with the pipeline between theelectropneumatic converter 9 and thecuff 1 through the pipeline, and the pressure signal output end of thepressure sensor 12 is connected to the pressure signal input end of the A/D converter 6;

光电容积传感器3设置于袖带1内,光电容积传感器3由第一波长发光二极管、第二波长发光二极管和光电二极管组成,脉冲发生器2的第一脉冲信号输出端连接第一波长发光二极管的脉冲信号输入端,脉冲发生器2的第二脉冲信号输出端连接第二波长发光二极管的脉冲信号输入端,脉冲发生器2的第三脉冲信号输出端连接光电二极管的第一驱动信号输入端,脉冲发生器2的第四脉冲信号输出端连接光电二极管的第二驱动信号输入端,脉冲发生器2的第一脉冲信号和第三脉冲信号同时导通或关闭,脉冲发生器2的第二脉冲信号和第四脉冲信号同时关闭或导通,光电二极管分别用于采集第一波长发光二极管和第二波长发光二极管的光电容积信号,光电二极管的采集信号输出端连接波峰保持器4的采集信号输入端,波峰保持器4的对应于第一波长发光二极管的波长信号输出端同时连接第一高通滤波器5-1的光波信号输入端和第一低通滤波器5-2和光波信号输入端,第一高通滤波器5-1的光波信号输出端连接A/D转换器6的第一模拟信号输入端,第一低通滤波器5-2的光波信号输出端连接A/D转换器6的第二模拟信号输入端,波峰保持器4的对应于第二波长发光二极管的波长信号输出端同时连接第二高通滤波器5-3的光波信号输入端和第二低通滤波器5-4和光波信号输入端,第二高通滤波器5-3的光波信号输出端连接A/D转换器6的第三模拟信号输入端,第二低通滤波器5-4的光波信号输出端连接A/D转换器6的第四模拟信号输入端,A/D转换器6的数字信号输出端连接计算机8的采集信号输入端。Thephotocapacitive volume sensor 3 is arranged in thecuff 1, thephotocapacitive volume sensor 3 is made up of a first wavelength light-emitting diode, a second wavelength light-emitting diode and a photodiode, and the first pulse signal output end of thepulse generator 2 is connected to the first wavelength light-emitting diode. The pulse signal input end, the second pulse signal output end of thepulse generator 2 is connected to the pulse signal input end of the second wavelength light-emitting diode, the third pulse signal output end of thepulse generator 2 is connected to the first drive signal input end of the photodiode, The fourth pulse signal output end of thepulse generator 2 is connected to the second drive signal input end of the photodiode, the first pulse signal and the third pulse signal of thepulse generator 2 are turned on or off simultaneously, and the second pulse signal of thepulse generator 2 The signal and the fourth pulse signal are turned off or turned on at the same time, and the photodiodes are used to collect the photocapacitance signals of the first wavelength light-emitting diode and the second wavelength light-emitting diode respectively, and the collection signal output end of the photodiode is connected to the collection signal input of thepeak holder 4 end, the wavelength signal output end of thepeak holder 4 corresponding to the first wavelength light-emitting diode is simultaneously connected to the light wave signal input end of the first high-pass filter 5-1 and the first low-pass filter 5-2 and the light wave signal input end, The optical signal output end of the first high-pass filter 5-1 is connected to the first analog signal input end of the A/D converter 6, and the optical signal output end of the first low-pass filter 5-2 is connected to the A/D converter 6. The second analog signal input terminal, the wavelength signal output terminal corresponding to the second wavelength light-emitting diode of thepeak holder 4 is connected to the light wave signal input terminal of the second high-pass filter 5-3 and the second low-pass filter 5-4 and Light wave signal input end, the light wave signal output end of the second high-pass filter 5-3 connects the third analog signal input end of A/D converter 6, the light wave signal output end of the second low pass filter 5-4 connects A/D The fourth analog signal input end of theD converter 6 and the digital signal output end of the A/D converter 6 are connected to the acquisition signal input end of thecomputer 8 .

本实施方式中,设置有功率放大器11,由于D/A转换器7输出的指令信号一般较小,难以控制电空变换器9的动作。因此,在D/A转换器7与电空变换器9之间设置功率放大器11,将输出的电压信号进行功率放大,达到控制电空变换器9动作、调节进入袖带的空气量,使袖带内的压力以一定的速率上升的目的。In this embodiment, apower amplifier 11 is provided, and since the command signal output by the D/A converter 7 is generally small, it is difficult to control the operation of the electro-pneumatic converter 9 . Therefore, apower amplifier 11 is set between the D/A converter 7 and theelectropneumatic converter 9, and the output voltage signal is amplified to control the operation of theelectropneumatic converter 9, adjust the air volume entering the cuff, and make the cuff The purpose of the pressure inside the belt to rise at a certain rate.

具体实施方式二:本实施方式为对实施方式一的进一步说明,第一波长发光二极管的发光波长为940nm,第二波长发光二极管的发光波长为805nm,光电二极管的感光波长中心范围为805nm至940nm。Specific Embodiment 2: This embodiment is a further description ofEmbodiment 1. The light-emitting wavelength of the light-emitting diode with the first wavelength is 940nm, the light-emitting wavelength of the light-emitting diode with the second wavelength is 805nm, and the photosensitive wavelength center range of the photodiode is 805nm to 940nm .

光电容积传感器3由两个不同波长的发光二极管LED和一个光电二极管PD组成。两波长LED作为光源可采用一体型结构。吸收反射光的PD其感光波长需覆盖805nm和940nm的范围,即可以有效吸收两波长LED的反射光。The photocapacitivevolumetric sensor 3 consists of two light-emitting diodes LED with different wavelengths and a photodiode PD. Two-wavelength LEDs can be used as a light source in an integrated structure. The photosensitive wavelength of the PD that absorbs reflected light needs to cover the range of 805nm and 940nm, that is, it can effectively absorb the reflected light of LEDs with two wavelengths.

具体实施方式三:本实施方式为对实施方式一或二的进一步说明,脉冲发生器2的驱动频率为500Hz。Embodiment 3: This embodiment is a further description ofEmbodiment 1 or 2, and the driving frequency of thepulse generator 2 is 500 Hz.

具体实施方式四:本实施方式为对实施方式一、二或三的进一步说明,所述脉冲发生器2的第一脉冲信号和第二脉冲信号的关系为:在脉冲发生器2脉冲信号的一个循环周期内,第一脉冲信号和第二脉冲信号的导通时间各为1/3周期,第一脉冲信号和第二脉冲信号交替导通或关闭的时间差为1/6周期。Specific Embodiment 4: This embodiment is a further description ofEmbodiment 1, 2 or 3. The relationship between the first pulse signal and the second pulse signal of thepulse generator 2 is: in one pulse signal of thepulse generator 2 In the cycle period, the turn-on time of the first pulse signal and the second pulse signal is 1/3 cycle, and the time difference between the first pulse signal and the second pulse signal being turned on or off alternately is 1/6 cycle.

基于实施方式一所述血压与血氧饱和度的同时检测装置的血压与血氧饱和度的同时检测方法,它包括以下步骤:The simultaneous detection method of blood pressure and blood oxygen saturation based on the simultaneous detection device of blood pressure and blood oxygen saturation described inEmbodiment 1 includes the following steps:

步骤一:将光电容积传感器3设置在袖带1内表面与皮肤的接触面之间;Step 1: disposing the photoelectricvolumetric sensor 3 between the inner surface of thecuff 1 and the contact surface of the skin;

步骤二:通过调节电空变换器9来调节进入袖带1内的进气量,使袖带1内的压力以5mmHg/S的速率上升,直至达到规定的压力;Step 2: adjust the air intake into thecuff 1 by adjusting the electro-pneumatic converter 9, so that the pressure in thecuff 1 rises at a rate of 5 mmHg/S until reaching a specified pressure;

步骤三:控制脉冲发生器2输出四个脉冲信号,使脉冲发生器2的第一脉冲信号和第三脉冲信号同时导通的同时,第二脉冲信号和第四脉冲信号同时关闭;脉冲发生器2的第二脉冲信号和第四脉冲信号同时导通的同时,第一脉冲信号和第三脉冲信号同时关闭,来实现对两个发光二极管的间歇驱动,同时光电二极管在每个发光二极管分别点亮的同时,采集相应的发光二极管的光电容积信号;Step 3: Control thepulse generator 2 to output four pulse signals, so that the first pulse signal and the third pulse signal of thepulse generator 2 are turned on at the same time, and the second pulse signal and the fourth pulse signal are turned off at the same time; thepulse generator 2. When the second pulse signal and the fourth pulse signal of 2 are turned on at the same time, the first pulse signal and the third pulse signal are turned off at the same time to realize the intermittent driving of the two light-emitting diodes. At the same time, collect the photovolume signal of the corresponding light-emitting diode;

步骤四:波峰保持器4根据脉冲发生器2的脉冲逻辑将光电二极管检测获得的两种波长的反射光信号分别输出,由计算机8对所有的采集数据进行处理,获得被检测部位的血压与血氧饱和度数值。Step 4: According to the pulse logic of thepulse generator 2, thepeak holder 4 outputs the reflected light signals of the two wavelengths obtained by the photodiode detection respectively, and thecomputer 8 processes all the collected data to obtain the blood pressure and blood pressure of the detected part. Oxygen saturation value.

本实施方式中,由电空变换器9和气泵10组成的袖带压力调节系统中,气泵10是常供气的,因此进入袖带内空气量的多少是由电空变换器9调节自身电磁阀开口的大小来确定的。与此同时,袖带内进气量带来的压力变化通过压力传感器12检出。In the present embodiment, in the cuff pressure regulation system that is made up of electro-pneumatic converter 9 andair pump 10,air pump 10 is often supplied with air, so how much air enters the cuff is regulated by electro-pneumatic converter 9 self electromagnetic Determined by the size of the valve opening. At the same time, the pressure change caused by the air intake in the cuff is detected by thepressure sensor 12 .

本实施方式的步骤二中所述的规定压力,对于一般使用者而言可定为使用者的正常压力上加30~50mmHg。The specified pressure mentioned instep 2 of this embodiment can be set as 30-50 mmHg plus 30-50 mmHg to the user's normal pressure for general users.

步骤四中计算机8对采集数据进行处理获得血压数值的方法为:计算机8将A/D转换器6采集获得的第二高通滤波器5-3的光波信号与压力传感器12采集获得的袖带1内的压力信号采用容积振动法进行计算,得到平均血压和伸缩压的数值,并经计算得到舒张压的数值。InStep 4, the method for thecomputer 8 to process the collected data to obtain the blood pressure value is as follows: thecomputer 8 combines the light wave signal of the second high-pass filter 5-3 collected by the A/D converter 6 with thecuff 1 obtained by thepressure sensor 12. The internal pressure signal is calculated by the volume vibration method to obtain the values of the average blood pressure and the systolic pressure, and the value of the diastolic pressure is obtained through calculation.

关于血压数值的计算方法:对于光电容积传感器3中的一个发光二极管,通过检测其光电容积PGac信号,或反射光的变化量ΔIλ信号,利用容积振动法确定间接血压的最高值SBP以及平均值MBPCalculation method of blood pressure value: For a light-emitting diode in thephotoelectric volume sensor 3, by detecting its photoelectric volume PGac signal, or the change amount ΔIλ signal of reflected light, use the volume vibration method to determine the highest value SBP and the average value of the indirect blood pressure MBP

步骤四中计算机8对采集数据进行处理获得血氧饱和度数值的方法为:InStep 4, thecomputer 8 processes the collected data to obtain the blood oxygen saturation value as follows:

首先,当被检测部位没有受到袖带1压迫时,其吸光度Aλi为:First, when the detected part is not compressed by thecuff 1, its absorbance Aλi is:

AAλiλ i==loglog((II00λλii//IIλλii))==((ϵϵHbHbλλiiCCHbHbaa++ϵϵHboHboλλiiCCHboHboaa))ddaa++((ϵϵHbHbλλiiCCHbHbvv++ϵϵHboHboλλiiCCHboHbovv))ddvv++ϵϵttλλiiCCttddtt++BBλλii,,

I0λi为入射光量,Iλi为反射光量,λi=λ1,λ2,λ1为对应于第一波长发光二极管的光波信号,λ2为对应于第二波长发光二极管的光波信号,I0λi is the amount of incident light, Iλi is the amount of reflected light, λi=λ1, λ2, λ1 is the light wave signal corresponding to the first wavelength light-emitting diode, λ2 is the light wave signal corresponding to the second wavelength light-emitting diode,

Figure BDA00001811866400052
为还原血红蛋白Hb的吸光系数,
Figure BDA00001811866400052
is the absorbance coefficient of reduced hemoglobin Hb,

Figure BDA00001811866400053
为动脉血液的还原血红蛋白Hb浓度,为氧合血红蛋白Hbo的吸光系数,
Figure BDA00001811866400053
is the concentration of reduced hemoglobin Hb in arterial blood, is the absorbance coefficient of oxyhemoglobin Hbo,

Figure BDA00001811866400055
为动脉血液的氧合血红蛋白Hbo浓度,
Figure BDA00001811866400055
is the concentration of oxyhemoglobin Hbo in arterial blood,

da为动脉血液的光路长度,

Figure BDA00001811866400056
为动脉血液的还原血红蛋白Hb浓度,
Figure BDA00001811866400057
为动脉血液的氧合血红蛋白Hbo浓度,da is the optical path length of arterial blood,
Figure BDA00001811866400056
is the concentration of reduced hemoglobin Hb in arterial blood,
Figure BDA00001811866400057
is the concentration of oxyhemoglobin Hbo in arterial blood,

dv为静脉血液的光路长度,

Figure BDA00001811866400058
为肌肉组织的吸光系数,Ct为肌肉组织的浓度,dv is the optical path length of venous blood,
Figure BDA00001811866400058
is the absorption coefficient of muscle tissue, Ct is the concentration of muscle tissue,

dt为肌肉组织的光路长度,

Figure BDA00001811866400059
为散乱光的吸收;dt is the optical path length of the muscle tissue,
Figure BDA00001811866400059
for the absorption of scattered light;

当被检测部位受到的袖带1压迫使动脉血管不发生变化,只有静脉血管发生变化时,对应于第一波长发光二极管的波长λ1和第二波长发光二极管的波长λ2分别在V1状态下的吸光度

Figure BDA000018118664000510
Figure BDA000018118664000511
和V2状态下的吸光度
Figure BDA000018118664000513
分别为:When the pressure of thecuff 1 on the detected part makes the arterial blood vessels not change, and only the venous blood vessels change, the wavelength λ1 corresponding to the first wavelength light-emitting diode and the wavelength λ2 of the second-wavelength light-emitting diode are respectively inV1 state. Absorbance
Figure BDA000018118664000510
Figure BDA000018118664000511
and the absorbance in the V2 state and
Figure BDA000018118664000513
They are:

AAvv11λλ11==loglog((II00λλ11//IIvv11λλ11))==((ϵϵHbHbλλ11CCHbHbaa++ϵϵHboHboλλ11CCHboHboaa))ddaa++((ϵϵHbHbλλ11CCHbHbvv++ϵϵHboHboλλ11CCHboHbovv))ddvv11++ϵϵttλλ11CCttddtt++BBλλ11,,

AAvv11λλ22==loglog((II00λλ22//IIvv11λλ22))==((ϵϵHbHbλλ22CCHbHbaa++ϵϵHboHboλλ22CCHboHboaa))ddaa++((ϵϵHbHbλλ22CCHbHbvv++ϵϵHboHboλλ22CCHboHbovv))ddvv11++ϵϵttλλ22CCttddtt++BBλλ22,,

AAvv22λλ11==loglog((II00λλ11//IIvv22λλ11))==((ϵϵHbHbλλ11CCHbHbaa++ϵϵHboHboλλ11CCHboHboaa))ddaa++((ϵϵHbHbλλ11CCHbHbvv++ϵϵHboHboλλ11CCHboHbovv))ddvv22++ϵϵttλλ11CCttddtt++BBλλ11,,

AAvv22λλ22==loglog((II00λλ22//IIvv22λλ22))==((ϵϵHbHbλλ22CCHbHbaa++ϵϵHboHboλλ22CCHboHboaa))ddaa++((ϵϵHbHbλλ22CCHbHbvv++ϵϵHboHboλλ22CCHboHbovv))ddvv22++ϵϵttλλ22CCttddtt++BBλλ22,,

由于在v1、v2状态下动脉血管中的血液和肌肉组织的吸光度不发生变化,并假定在袖带加压的微小的区间内来自散乱光的吸收不变,则静脉血液两波长光的吸光度的差

Figure BDA00001811866400064
Figure BDA00001811866400065
分别为:Since the absorbance of the blood and muscle tissue in the arterial vessel does not change in the states of v1 and v2 , and assuming that the absorption of scattered light does not change in the small interval of cuff pressurization, the two-wavelength light of venous blood difference in absorbance
Figure BDA00001811866400064
and
Figure BDA00001811866400065
They are:

ΔΔAAvv11--vv22λλ11==AAvv11λλ11--AAvv22λλ11==((ϵϵHbHbλλ11CCHbHbvv++ϵϵHboHboλλ11CCHboHbovv))ΔΔddvv11--vv22,,

ΔΔAAvv11--vv22λλ22==AAvv11λλ22--AAvv22λλ22==((ϵϵHbHbλλ22CCHbHbvv++ϵϵHboHboλλ22CCHboHbovv))ΔΔddvv11--vv22,,

式中为v1与v2状态下静脉血液的光路长度差,In the formula is the optical path length difference of venous blood in v1 and v2 states,

当被检测部位受到的袖带1压迫使动静脉血管闭锁,肌肉组织与散乱光的吸光特性不变,只有动脉血管中的血液的光路发生变化,假定对应于第一波长发光二极管的波长λ1和第二波长发光二极管的波长λ2分别为a1和a2状态时,动脉血液两波长光的吸光度的差

Figure BDA00001811866400069
Figure BDA000018118664000610
分别为:When the pressure of thecuff 1 on the detected part makes the arterial and venous vessels blocked, the light absorption properties of the muscle tissue and scattered light remain unchanged, and only the light path of the blood in the arterial vessel changes. Assuming that the wavelengths λ1 and λ1 of the light-emitting diode corresponding to the first wavelength When the wavelength λ2 of the light-emitting diode of the second wavelength is in the state of a1 and a2 respectively, the difference in the absorbance of arterial blood at two wavelengths
Figure BDA00001811866400069
and
Figure BDA000018118664000610
They are:

ΔΔAAaa11--aa22λλ11==AAaa11λλ11--AAaa22λλ11==((ϵϵHbHbλλ11CCHbHbaa++ϵϵHboHboλλ11CCHboHboaa))ΔΔddaa11--aa22,,

ΔΔAAaa11--aa22λλ22==AAaa11λλ22--AAaa22λλ22==((ϵϵHbHbλλ22CCHbHbaa++ϵϵHboHboλλ22CCHboHboaa))ΔΔddaa11--aa22,,

Figure BDA000018118664000613
为a1和a2状态下动脉血液的光路长度差,
Figure BDA000018118664000613
is the optical path length difference of arterial blood in a1 and a2 states,

用SvO2表示静脉血氧饱和度,SaO2表示动脉血氧饱和度,则Use SvO2 to represent venous oxygen saturation, and SaO2 to represent arterial oxygen saturation, then

SvOSvO22==CCHboHbovv//((CCHboHbovv++CCHbHbvv)),,

SaOSaO22==CCHboHboaa//((CCHboHboaa++CCHbHbaa)),,

对上述所有公式求解获得静脉血氧饱和度SvO2和动脉血氧饱和度SaO2Solve all the above formulas to obtain venous oxygen saturation SvO2 and arterial oxygen saturation SaO2 :

SvOSvO22==ϵϵHbHbλλ11ϵϵHbHbλλ11--ϵϵHboHboλλ11--ββϵϵHbHbλλ11--ϵϵHboHboλλ11××ΔΔAAvv11--vv22λλ11ΔΔAAvv11--vv22λλ22,,

SvOSvO22==ϵϵHbHbλλ11ϵϵHbHbλλ11--ϵϵHboHboλλ11--ββϵϵHbHbλλ11--ϵϵHboHboλλ11××ΔΔAAaa11--aa22λλ11ΔΔAAaa11--aa22λλ22,,

式中β为λ2选择还原血红蛋白Hb与氧合血红蛋白Hbo具有等吸收点波长时还原血红蛋白Hb与氧合血红蛋白Hbo的吸收系数。In the formula, β is the absorption coefficient of reduced hemoglobin Hb and oxyhemoglobin Hbo when λ2 selects the wavelength of the isoabsorbance point of reduced hemoglobin Hb and oxyhemoglobin Hbo.

本实用新型中所涉及的动、、静脉血氧饱和度检测原理是:The arterial, venous blood oxygen saturation detection principle involved in the utility model is:

本实用新型采用两波长分光法进行动静脉血氧饱和度检测,考虑到人体检测部位的不同组织对透过光或反射光的吸收情况不同,可将检测部位简化成由肌肉组织、动脉和静脉构成的光学吸收模型,如图2所示。当通过袖带1给检测部位加压时,由于肌肉组织不可压缩,即加压过程中其厚度不发生变化,因此可考虑肌肉组织的光学特性是不变的。而静脉血管和动脉血管在袖带压力的作用下管内体积会不断缩小直至闭锁,由此带来了吸光特性的变化。首先,静脉血管的压力低,在袖带压的作用下先变形以致被完全压闭;而后,动脉血管逐渐被加压,以致动脉血管被完全压闭。将袖带1加压过程中吸光特性的变化记录下来,可以发现在吸光特性曲线上因静、动脉血管的力学特性不同有一个拐点存在。即,这个拐点的以前的部分是静脉血液的吸光特性的变化,以后的部分是动脉血液的吸光特性的变化。这样,就可以拐点为分界,通过吸光特性将静、动脉血液的成分分离出来。The utility model uses a two-wavelength spectroscopic method to detect arterial and venous blood oxygen saturation. Considering that different tissues in the detection parts of the human body absorb the transmitted light or reflected light differently, the detection parts can be simplified as muscle tissue, arteries and veins. The formed optical absorption model is shown in Fig. 2. When the detection site is pressurized by thecuff 1 , since the muscle tissue is incompressible, that is, its thickness does not change during the pressurization process, it can be considered that the optical properties of the muscle tissue remain unchanged. Under the action of cuff pressure, the volume of venous blood vessels and arterial blood vessels will continue to shrink until atresia, which brings about changes in light absorption characteristics. First, the pressure of the venous blood vessel is low, and it is deformed under the action of the cuff pressure so that it is completely occluded; then, the arterial blood vessel is gradually pressurized, so that the arterial blood vessel is completely occluded. By recording the changes of the light absorption characteristics during the pressurization process of thecuff 1, it can be found that there is an inflection point on the light absorption characteristic curve due to the difference in the mechanical properties of the static and arterial blood vessels. That is, the part before this inflection point is a change in the light absorption characteristic of venous blood, and the part after that is a change in the light absorption characteristic of arterial blood. In this way, the inflection point can be used as a boundary, and the static and arterial blood components can be separated through the light absorption characteristics.

本实施方式中当被检测部位没有受到袖带1压迫时,其吸光度Aλi的获得方法是根据Beer-Lambert定律获得的。由图2和图3可知,当袖带压较小时,动脉血管不发生变化,只有静脉血管发生变化。因此其对应的状态为V1,V2。当检测部位加压到图3中所示的a1、a2状态时,静脉血管已经闭锁,肌肉组织与散乱光的吸光特性的假定不变,则只有动脉血管中的血液的光路发生变化。In this embodiment, when the detected part is not pressed by thecuff 1 , its absorbance Aλi is obtained according to the Beer-Lambert law. It can be seen from Figure 2 and Figure 3 that when the cuff pressure is small, the arterial blood vessels do not change, only the venous blood vessels change. Therefore, its corresponding state is V1 , V2 . When the detection site is pressurized to the a1 and a2 states shown in Figure 3, the venous blood vessels have been blocked, and the assumption of the light absorption properties of muscle tissue and scattered light remains unchanged, only the optical path of the blood in the arterial blood vessels changes.

通过静脉血氧饱和度SvO2和动脉血氧饱和度SaO2的计算公式还可以算出代谢后血氧差,即:The post-metabolism blood oxygen difference can also be calculated through the calculation formula of venous blood oxygen saturationSvO2 and arterial blood oxygen saturationSaO2 , namely:

SaSa--vvOo22==ββϵϵHbHbλλ11--ϵϵHboHboλλ11××((ΔΔAAvv11--vv22λλ11ΔΔAAvv11--vv22λλ22--ΔΔAAaa11--aa22λλ11ΔΔAAaa11--aa22λλ22)),,

公式中的系数β,

Figure BDA00001811866400072
Figure BDA00001811866400073
可通过图4所示的Hb与Hbo对红光与红外光的吸收曲线求出,但考虑到光电传感器特性实际的离散性,通常还要通过实验定标来确定。The coefficient β in the formula,
Figure BDA00001811866400072
Figure BDA00001811866400073
It can be obtained through the absorption curves of Hb and Hbo for red light and infrared light shown in Figure 4, but considering the actual discreteness of the photoelectric sensor characteristics, it is usually determined through experimental calibration.

本实施方式中,通过检测两个LED的反射光Iλ信号,并进行取对数等相关处理计算出动、静脉血氧饱和度。两波长LED采用脉冲驱动,驱动频率可选为500Hz。为了得到每个LED对检测部位的吸收情况,对两个LED实行间歇驱动。即,一个LED点亮时,另一个LED熄灭,反之亦然。与其相对应,PD也是间歇接通,分别检测出两波长LED的反射光信号,并通过采样保持回路使检测到的信号成为连续的曲线。局部加压袖带中的压力信号是通过一个内装温度补偿和信号放大的压力传感器检出,作为确定血管内部血压的依据。上述检出的光电信号与压力信号通过16位A/D转换器输入到计算机中,并在这里进行数据的处理、记录与存储;与此同时,袖带内压力的控制计算也在这里进行,并由这里向电空变换器9下达指令,控制进入袖带的空气量,使袖带内的压力以一定的速率上升。In this embodiment, the arterial and venous blood oxygen saturation is calculated by detecting the reflected light Iλ signals of two LEDs, and performing correlation processing such as logarithm. The two-wavelength LEDs are driven by pulses, and the driving frequency can be selected as 500Hz. In order to obtain the absorption of each LED to the detection site, the two LEDs are driven intermittently. That is, when one LED is on, the other is off, and vice versa. Correspondingly, the PD is also turned on intermittently to detect the reflected light signals of the LEDs with two wavelengths respectively, and make the detected signals into a continuous curve through the sample-and-hold circuit. The pressure signal in the partial pressurization cuff is detected by a pressure sensor with built-in temperature compensation and signal amplification, as the basis for determining the blood pressure inside the blood vessel. The photoelectric signal and pressure signal detected above are input into the computer through a 16-bit A/D converter, and the data is processed, recorded and stored here; at the same time, the control calculation of the pressure in the cuff is also carried out here. From here, an instruction is issued to theelectropneumatic converter 9 to control the amount of air entering the cuff so that the pressure in the cuff rises at a certain rate.

所述还原血红蛋白Hb与氧合血红蛋白Hbo具有的等吸收点波长为805nm。The isoabsorptive point wavelength of the reduced hemoglobin Hb and oxyhemoglobin Hbo is 805 nm.

Claims (4)

1. checkout gear blood pressure and blood oxygen saturation the time; It comprises cuff (1); It is characterized in that: it also comprises pulse generator (2); Photoelectricity volume sensor (3); Crest keeper (4); First high pass filter (5-1); First low pass filter (5-2); Second high pass filter (5-3); Second low pass filter (5-4); A/D converter (6); D/A converter (7); Computer (8); Electricity space-variant parallel operation (9); Air pump (10); Power amplifier (11) and pressure transducer (12)
Air pump (10) is cuff (a 1) air feed through pipeline; Electricity space-variant parallel operation (9) is arranged on the pipeline between air pump (10) and the cuff (1); The control signal input of electricity space-variant parallel operation (9) connects the control signal output ends of power amplifier (11); The control signal input of power amplifier (11) connects the analog signal output of D/A converter (7), and the digital signal input end of D/A converter (7) connects the control signal output ends of computer (8);
The pressure acquisition end of pressure transducer (12) is through the pipeline connection between pipeline and electric space-variant parallel operation (9) and the cuff (1), and the pressure signal outfan of pressure transducer (12) connects the pressure signal input of A/D converter (6);
Photoelectricity volume sensor (3) is arranged in the cuff (1); Photoelectricity volume sensor (3) is made up of the first wavelength light emitting diode, the second wavelength light emitting diode and photodiode; First pulse signal output end of pulse generator (2) connects the pulse signal input terminal of the first wavelength light emitting diode; Second pulse signal output end of pulse generator (2) connects the pulse signal input terminal of the second wavelength light emitting diode; The 3rd pulse signal output end of pulse generator (2) connects first driving signal input of photodiode; The 4th pulse signal output end of pulse generator (2) connects second driving signal input of photodiode; First pulse signal of pulse generator (2) and the 3rd pulse signal conducting simultaneously or close; Second pulse signal and the 4th pulse signal of pulse generator (2) are closed or conducting simultaneously; Photodiode is respectively applied for the photoelectricity plethysmogram signal of gathering the first wavelength light emitting diode and the second wavelength light emitting diode; The acquired signal outfan of photodiode connects the acquired signal input of crest keeper (4); The wavelength signals outfan corresponding to the first wavelength light emitting diode of crest keeper (4) connects lightwave signal input and first low pass filter (5-2) and the lightwave signal input of first high pass filter (5-1) simultaneously; The lightwave signal outfan of first high pass filter (5-1) connects first input end of analog signal of A/D converter (6); The lightwave signal outfan of first low pass filter (5-2) connects second input end of analog signal of A/D converter (6); The wavelength signals outfan corresponding to the second wavelength light emitting diode of crest keeper (4) connects lightwave signal input and second low pass filter (5-4) and the lightwave signal input of second high pass filter (5-3) simultaneously; The lightwave signal outfan of second high pass filter (5-3) connects the 3rd input end of analog signal of A/D converter (6), and the lightwave signal outfan of second low pass filter (5-4) connects the 4th input end of analog signal of A/D converter (6), and the digital signal output end of A/D converter (6) connects the acquired signal input of computer (8).
2. checkout gear in the time of blood pressure according to claim 1 and blood oxygen saturation; It is characterized in that: the emission wavelength of the first wavelength light emitting diode is 940nm; The emission wavelength of the second wavelength light emitting diode is 805nm, and the wavelength photoreceptor center range of photodiode is 805nm to 940nm.
3. checkout gear in the time of blood pressure according to claim 1 and 2 and blood oxygen saturation is characterized in that: the driving frequency of pulse generator (2) is 500Hz.
4. checkout gear in the time of blood pressure according to claim 1 and 2 and blood oxygen saturation; It is characterized in that: first pulse signal of said pulse generator (2) and the relation of second pulse signal are: in a cycle period of pulse generator (2) pulse signal; The ON time of first pulse signal and second pulse signal respectively was 1/3 cycle, and first pulse signal and the second pulse signal alternate conduction or the time difference of closing were 1/6 cycle.
CN 2012203022832012-06-262012-06-26Blood pressure and blood oxygen saturation degree simultaneous detection deviceExpired - LifetimeCN202589509U (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication numberPriority datePublication dateAssigneeTitle
CN102715893A (en)*2012-06-262012-10-10黑龙江大学Device and method for detecting blood pressure and oxyhemoglobin saturation simultaneously
CN105699306A (en)*2016-03-282016-06-22武汉理工大学Double-wavelength testing device applicable to judgment of firing delay time of shock tube
CN107019504A (en)*2017-06-022017-08-08黑龙江大学A kind of blood pressure detector and method based on volume pulsation wave graded

Cited By (5)

* Cited by examiner, † Cited by third party
Publication numberPriority datePublication dateAssigneeTitle
CN102715893A (en)*2012-06-262012-10-10黑龙江大学Device and method for detecting blood pressure and oxyhemoglobin saturation simultaneously
CN102715893B (en)*2012-06-262014-02-26黑龙江大学 Device and method for simultaneous detection of blood pressure and blood oxygen saturation
CN105699306A (en)*2016-03-282016-06-22武汉理工大学Double-wavelength testing device applicable to judgment of firing delay time of shock tube
CN105699306B (en)*2016-03-282018-06-22武汉理工大学Suitable for the dual wavelength test device of shock tube ignition delay time judgement
CN107019504A (en)*2017-06-022017-08-08黑龙江大学A kind of blood pressure detector and method based on volume pulsation wave graded

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