CN202113876U - Vacuum sealed glass test tube - Google Patents

Abstract

The utility model discloses a vacuum sealed glass test tube, which comprises a tube body and a plug component arranged at an opening. The upper diameter and the lower diameter of the tube body are consistent, the plug component comprises a rubber plug and a ring-pull cap, the rubber plug is sealed in the opening of the tube body in a vacuumed manner, and the ring-pull cap is fixed to the periphery of the opening. During specific use, the vacuum sealed glass test tube can be used for freezing and drying contents therein, can be sealed by the butyl rubber plug in a vacuum state after freezing and drying of the contents and can be fixed by the aid of the ring-pull cap, and a general pipette tip can extend into the bottom of the test tube directly. The vacuum sealed glass test tube is not only a packaging container but a reaction container, can be used as internal package for bioactive constituent of drugs, biological products, test agents and the like, and can also be directly used for constant-temperature biological or chemical reaction inside.

Description

Vacuum seal teat glass bottle

Technical field

The utility model discloses a kind of vacuum seal teat glass bottle, divides by International Patent Classification (IPC) (IPC) to belong to medicine or container manufacturing technology fields such as biological products, reagent.

Background technology

Bioactivators such as traditional medicine, biological products or detectable need carry out the freeze drying long preservation, and its packing container is generally glass glass tube vial or glass ampule.In addition, some bioactive ingredients use or testing process in, need be divided in addition in the glass reaction test tube, place that the adding sample reacts constant temperature under.

At present, the bioactive ingredients that is packaged in the glass ampule need take out in freeze drier after freeze drying finishes, and molten glass seals under aseptic condition.Bioactive ingredients directly contacts with surrounding environment in this process, and is contaminated easily, and the process of sealing length consuming time, causes the bioactive ingredients moisture absorption easily, and moisture is too high, causes active unstable.And the bioactive ingredients of the glass ampule packing glass ampule that must fracture when using, the operator is hurt by the ampoule opening easily; In addition, the last bore of glass ampule is very little, pipettes solution at the bottom of the pipettor suction nozzle can't stretch to bottle, uses inconvenient.

According to the pharmacopeia relevant regulations; Medicine, biological products or detectable etc. after freeze drying, are packed and concrete operational phase has corresponding requirement to container; Those skilled in the art are according to afore mentioned rules, and medicine, biological products or detectable etc. are used different containers in above-mentioned two stages.

Summary of the invention

Deficiency to prior art; The utility model provides a kind of vacuum seal teat glass bottle; This teat glass bottle is a packing container; Also be container biological, chemical reaction, the bioactive ingredients that is packaged in this teat glass can carry out the freeze drying long preservation, and can directly in this container, carry out the biochemical reaction of constant temperature behind the opening.

For achieving the above object, the utility model is realized through following technical scheme:

A kind of vacuum seal teat glass bottle comprises bottle and is arranged at the stopper member of bottle mouth position, wherein, bottle, by body, bottleneck week along and between the two bottleneck constitute, described body has identical diameter up and down;

Stopper member, it is vacuum-sealed in the bottle mouth position of bottle.

Further, the internal diameter of all edges of described bottleneck and bottleneck is identical, and the internal diameter of all edges of bottleneck and bottleneck is slightly less than the internal diameter of body.

Further, described stopper member comprises rubber stopper and easy-to-draw ring cowling, and rubber stopper is vacuum-sealed in the bottle mouth position of bottle, and is fixed in bottleneck week edge by an easy-to-draw ring cowling, and the lower edge of this easy-to-draw ring cowling is snapped in the downside circumferential edges on bottleneck week edge.

Further; Described easy-to-draw ring cowling is by aluminium lid and top cap, wherein aluminium lid by draw ring and on every side lid form, draw ring is positioned at lid top center position and is connected with the top cap; Wherein lid is reached the lid of forming ring-type with the draw ring extension by left and right arcus part; Lid to extend below coating bottleneck week along and rubber stopper be positioned at the part bottleneck outside, described left and right arcus part and encircle between the extension line of weakness is arranged is opened rubber stopper conveniently to tear aluminium lid.

Further, described rubber stopper is a butyl rubber plug, and it is vacuum-sealed in the bottleneck of bottle and extends to body, and the chock plug of butyl rubber plug has the breach structure.

Further, be filled with medicine, biological products, TAL, endotoxin or other detectable dry products in the described bottle.

Further, described bottle body bottom is flat or arcuate bottom, and the bottle height overall is 70.0mm～80.0mm, and wherein the external diameter of body is 11.0mm～12.0mm, and the body internal diameter is 6.5mm～8.5mm.

The utility model discloses a kind of vacuum seal teat glass bottle; Comprise bottle and be arranged at the stopper member of bottle mouth position; Body has identical diameter up and down; Stopper member comprises rubber stopper and easy-to-draw ring cowling, and rubber stopper is vacuum-sealed in the bottle mouth position of bottle, and is fixed in bottleneck week edge by an easy-to-draw ring cowling.It is in vitro tolerant to be used for freeze drying during concrete the use, and can finish the back in freeze drying and under vacuum state, add the butyl rubber plug sealing and reinforced by easy-to-draw ring cowling, and general pipettor suction nozzle can directly stretch into the test tube bottom.The utility model is a kind of packing container, also is a kind of reaction vessel, can be used as the inner packing of bioactive ingredients such as medicine, biological products, detectable, and can directly in this container, carry out homoiotherm or chemical reaction.

The utility model can be used for medicine, biological products, TAL, endotoxin or the can of detectable dry product in bottle, under vacuum state, adding butyl rubber plug after the freeze drying and sealing, and after taking out from freeze drier, adds easy-to-draw aluminium lid and reaches fixedly plug.The utility model is furnished with the cryodesiccated butyl rubber plug of being fit to, and can add fixedly plug of easy-to-draw aluminium lid after sealing with butyl rubber plug, has further guaranteed the seal of container.

The utility model has the advantages that: being the preservation container of bioactivator, also is reaction vessel.Bioactivator in being kept at can carry out freeze drying, and after freeze drying, adds butyl rubber plug and seal.Bioactivator in being kept at can directly carry out isothermal reaction under 37oC water-bath or xeothermic state, body is long, and band butyl rubber plug lid, is difficult in the course of reaction polluting.The utility model is furnished with easy-to-draw aluminium lid, and opening is easy, does not hinder hand.

Description of drawings

Fig. 1 is the utility model sketch map;

Fig. 2 is another sketch map of the utility model;

Fig. 3 is the utility model decomposing schematic representation;

Fig. 4 is another angle exploded view of the utility model.

The specific embodiment

Below in conjunction with accompanying drawing the utility model is described further:

Embodiment: see also Fig. 1 and Fig. 3, Fig. 4, a kind of vacuum seal teat glass bottle comprisesbottle 1 and is arranged at thestopper member 2 of bottle mouth position; Wherein,Bottle 1 is made up ofbody 11, alledges 12 of bottleneck andbottleneck 13 between the two, and describedbody 11 has identical diameter up and down;Stopper member 2, it is vacuum-sealed in the bottle mouth position of bottle 1.The internal diameter of alledges 12 of bottleneck andbottleneck 13 is identical, and the internal diameter of all edges of bottleneck and bottleneck is slightly less than the internal diameter of body 11.Stopper member 2 comprisesrubber stopper 21 and easy-to-draw ring cowling 22, andrubber stopper 21 is vacuum-sealed in the bottle mouth position ofbottle 1, and is fixed in bottleneck week edge by an easy-to-draw ring cowling 22, and the lower edge of this easy-to-draw ring cowling 22 is snapped in the downside circumferential edges on alledges 12 of bottleneck.Easy-to-draw ring cowling 22 is byaluminium lid 221 andtop cap 222; Whereinaluminium lid 221 by drawring 2210 and on every side lid form; Drawring 2210 is positioned at lid top center position and is connected with the top cap; Wherein lid is formed the lid of ring-type by left andright arcus part 2211,2212 and withdraw ring extension 2213, lid to extend below coatingbottleneck week edge 12 andrubber stopper 21 be positioned at the part outside the bottleneck, between described left andright arcus part 2211,2212 and thedraw ring extension 2213 line ofweakness 301 is arranged; Specifically see Fig. 1 or Fig. 2, open rubber stopper conveniently to tear aluminiumlid.Rubber stopper 21 is a butyl rubber plug, and be sealed in the bottleneck of bottle and extend tobody 11 its true appearance, and the chock plug of butyl rubber plug has the breach structure.Above-mentioned top cap is the plastic top cap.

Being filled with content P in the utility model bottle, specifically can be medicine, biological products, TAL, endotoxin or other detectable dry products.Bottle 1 bottom be flat or arcuate bottom or circular arc at the bottom of, like Fig. 1 and shown in Figure 2, wherein the bottle height overall (length) of the utility model is 70.0mm～80.0mm, is preferably 74.0 ± 0.5mm; Wherein the external diameter of body is 11.0mm～12.0mm, is preferably 11.7 ± 0.2; The body internal diameter is 6.5mm～8.5mm, is preferably 7.5 ± 0.5.

The utility model vacuum seal teat glass relates to that a kind of can be used for freeze drying in vitro tolerant, and can finish the back in freeze drying and under vacuum state, add butyl rubber plug sealed glass test tube.Described teat glass diameter is unanimous between the higher and lower levels, is 6.5-8.5mm, and length is 70.0-80.0mm, and general pipettor suction nozzle can directly stretch into the test tube bottom.At the bottom of teat glass bottom is flat or circular arc.The utility model is a kind of packing container, also is a kind of reaction vessel, can be used as the inner packing of bioactive ingredients such as medicine, biological products, detectable, and can directly in this container, carry out homoiotherm or chemical reaction.

The utility model is as single test gel method TAL container, and concrete operations are following:

Get gel method TAL 0.1ml, can adds butyl rubber plug after the freeze drying and seals in the utility model under vacuum state.After the freeze drier taking-up, add fixedly plug of easy-to-draw aluminium lid.

During use, add 0.2ml sample dissolution TAL, cover butyl rubber plug, jolting dissolving TAL powder places 37oC water bath with thermostatic control reaction 60 minutes gently, after constant temperature finishes, test tube is taken out from constant water bath box gently, slowly reverses 180 °.If in vitro tolerantly be solid gel, indeformable, not positive from tube wall slippage person, positive findings is represented the sensitivity that the bacteria endotoxin content in the sample indicates more than or equal to the gel method TAL; Though be not gel or generate gel but can not be kept perfectly and negative from tube wall slippage person, negative findings is represented the sensitivity that the bacteria endotoxin content in the sample indicates less than the gel method TAL.

The above record is merely the embodiment that utilizes this origination techniques content, anyly is familiar with modification, the variation that this creation of this art utilization is done, and all belongs to the claim of this creation opinion, and is not limited to embodiment announcement person.

Claims (7)

1. vacuum seal teat glass bottle is characterized in that the stopper member that comprises bottle and be arranged at bottle mouth position, wherein:

Bottle, by constituting along the bottleneck that reaches between the two in body, bottleneck week, described body has identical diameter up and down;

Stopper member, it is vacuum-sealed in the bottle mouth position of bottle.

2. vacuum seal teat glass bottle according to claim 1 is characterized in that: the internal diameter of all edges of described bottleneck and bottleneck is identical, and the internal diameter of all edges of bottleneck and bottleneck is slightly less than the internal diameter of body.

3. vacuum seal teat glass bottle according to claim 1; It is characterized in that: described stopper member comprises rubber stopper and easy-to-draw ring cowling; Rubber stopper is vacuum-sealed in the bottle mouth position of bottle; And be fixed in bottleneck week edge by an easy-to-draw ring cowling, the lower edge of this easy-to-draw ring cowling is snapped in the downside circumferential edges on bottleneck week edge.

4. vacuum seal teat glass bottle according to claim 3; It is characterized in that: described easy-to-draw ring cowling is by aluminium lid and top cap; Wherein aluminium lid by draw ring and on every side lid form; Draw ring is positioned at lid top center position and is connected with the top cap, and wherein lid is formed the lid of ring-type by left and right arcus part and with the draw ring extension, lid to extend below coating bottleneck week the edge and rubber stopper be positioned at the part outside the bottleneck; Between described left and right arcus part and the ring extension line of weakness is arranged, open rubber stopper conveniently to tear aluminium lid.

5. vacuum seal teat glass bottle according to claim 4 is characterized in that: described rubber stopper is a butyl rubber plug, and it is vacuum-sealed in the bottleneck of bottle and extends to body, and the chock plug of butyl rubber plug has the breach structure.

6. vacuum seal teat glass bottle according to claim 1 is characterized in that: be filled with medicine, biological products, TAL, endotoxin or detectable dry product in the described bottle.

7. vacuum seal teat glass bottle according to claim 1 and 2; It is characterized in that: described bottle body bottom is flat or arcuate bottom; The bottle height overall is 70.0mm～80.0mm, and wherein the external diameter of body is 11.0mm～12.0mm, and the body internal diameter is 6.5mm～8.5mm.

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