CN202083637U - Detection device - Google Patents

Abstract

The utility model relates to a detection device which comprises a substrate; and the substrate comprises a detection area and a hand-held part which is convenient for a user to hold. The detection area comprises one or more detection reagent pads which can react or be integrated with substances to be analyzed in a submitted sample and send out detection signals, and the outline size of the hand-held part is bigger than that of other parts of the substrate. The hand-held part is a plastic piece which is injection molded, and comprises a channel. The channel and the substrate are provided with structures capable of tightly integrating the substrate and the hand-held part. The detection device has a simple structure, is convenient to use and has low cost.

Description

Pick-up unit

Technical field

The utility model relates to human or animal's body fluid sample analysis technical field, especially a kind of analyst of being used for or certain analyte of animal body fluid sample whether exist with and the pick-up unit of content.

Background technology

At present, be used for detecting the dry chemical method whether liquid solutions such as blood or urine exist certain composition or this component content, adopt usually and detect as Chinese patent application 200610033783.9 or the disclosed detection test paper of Chinese patent ZL200420012431.1 structure.Number of patent application is that 200610033783.9 describeddetection test paper 1 comprise thatpaper substrates bar 10 and the detection module that has thedetectable layer 20 of enzyme developer stick to base material one end.In patent ZL200420012431.1, be stained with multiple detectable module on the described base material.During detection test strips immersed in the urine after about 2 seconds, take out, normal temperature is observed change color after following 5 minutes, thereby judges the situation of analyte in the liquid.The base material of present employed detection test paper adopts papery or plastics usually, and test paper is the thin slice of elongated strip shaped normally, and is very inconvenient when the operator hands this test strip.

The utility model content

The purpose of this utility model is to provide a kind of dry chemical pick-up unit that the operator conveniently is affectedly bashful, and this pick-up unit is simple in structure, and is with low cost, easy to use.

The utility model relates to a kind of pick-up unit, comprises base material, and base material comprises detection zone and the Handheld Division that makes things convenient for the user to grip.Detection zone includes one or more detectable pads that can react or combine and provide detection signal with the analyte in the censorship sample, and the overall size of Handheld Division is bigger than the overall size of base material other parts.The Handheld Division is the plastic sheet of injection mo(u)lding, includes passage.Passage and base material are provided with the structure of being combined closely in base material and Handheld Division.The utility model is simple in structure, and is easy to use, with low cost.

A kind of pick-up unit, it is characterized in that: pick-up unit comprises base material, base material comprises detection zone and makes things convenient for the district of being affectedly bashful that the user grips, detection zone includes the detectable that can react or combine and provide detection signal with the analyte in the censorship sample, and the overall size of being affectedly bashful the district is bigger than the overall size of base material other parts.Foregoing pick-up unit is characterized in that: detection zone is positioned at an end of base material, is affectedly bashful the relative other end that the district is positioned at base material.

Foregoing pick-up unit is characterized in that: be affectedly bashful the district and include the Handheld Division, the Handheld Division is attached to the other end of base material with respect to detection zone after by the hard material manufacturing again.

Foregoing pick-up unit is characterized in that: the Handheld Division is the plastic sheet of injection mo(u)lding, includes passage, and base material inserts this passage with respect to the other end of detection zone, and combines closely with vias inner walls.

Foregoing pick-up unit is characterized in that: the inwall of Handheld Division passage is provided with the structure that increases the adhesion that combines with base material.

Foregoing pick-up unit is characterized in that: these structures can be selected from following technical proposal: vias inner walls is become coarse; In vias inner walls the tooth line is set; Dung is set in passage; Pinning is set in passage; Passage is designed to shape wide outside and narrow inside, and the size of wide portion is greater than the width of base material, and the size of narrow portion is less than the width of base material, after base material inserts passage, and base material two sides and channel side wall interference engagement.

Foregoing pick-up unit is characterized in that: the Handheld Division is the plastic sheet of a slice injection mo(u)lding, forms above-mentioned passage in injection molding process.

Foregoing pick-up unit is characterized in that: the Handheld Division is that the plastic sheet by two injection mo(u)ldings combines, and two plastic sheets are respectively equipped with the structure of buckle mutually, thereby makes the two in conjunction with forming the Handheld Division.

Foregoing pick-up unit is characterized in that: the structure of described mutual buckle is arranged on the projection and the button hole of two two opposite faces after the plastic sheet combination.

Foregoing pick-up unit is characterized in that: the structure of two plastic sheets is identical, and each plastic sheet is equipped with two projections and two button holes, and the set-up mode of projection and button hole just in time projection and button hole makes mutual snap close.

Foregoing pick-up unit is characterized in that: the bearing of trend of passage inner tooth thread is consistent with the direction of insertion of base material.

Foregoing pick-up unit is characterized in that: be provided with brace rod in two opposite faces of two plastic sheets after combination.

Foregoing pick-up unit is characterized in that: the outside surface of Handheld Division is provided with the level and smooth arc-shaped concave of conveniently being affectedly bashful.

Foregoing pick-up unit is characterized in that: the outside surface of Handheld Division is provided with anti-skidding salient point or tooth line.

Foregoing pick-up unit, it is characterized in that: base material is provided with a projection at a side of being affectedly bashful Qu Yiduan, at its another relative side recessed of being complementary of projection therewith is set then, the projection of base material one side just in time is formed at recessed of adjacent that base material adjacent side; Two sides of Handheld Division passage are respectively equipped with and the projection of base material side and recessed recessed of being complementary and projection, thus buckle combination mutually.

The beneficial effects of the utility model are: owing to only pointing the Handheld Division increase overall size that contacts with the operator, therefore both solved and be affectedly bashful inconvenient technical matters, only increase material seldom again.Simultaneously, because project organization is simple, craft science, required production equipment quantity is few, and the production equipment price is low, and required manpower is few, is convenient to automated production.Thereby cost is very cheap.In addition, the design also has the characteristics of environmental protection.

Description of drawings

Fig. 1 is the detection test paper structural representation of the utility model pick-up unit;

Fig. 2 is first kind of embodiment synoptic diagram of the utility model;

Fig. 3 is first kind of embodiment decomposing schematic representation of the utility model;

Fig. 4 is the upper plate plane front elevation among Fig. 3;

Fig. 5 is that upper plate among Fig. 4 is along the cut-open view of its centerline direction;

Fig. 6 is the lower plate planar elevation view among Fig. 3;

Fig. 7 is that lower plate among Fig. 6 is along the cut-open view of its centerline direction;

Fig. 8 is the second embodiment planar elevation view of lower plate in the utility model;

Fig. 9 is the 3rd an embodiment explosive view of the utility model pick-up unit;

Figure 10 is the sectional view after the combination of the utility model the 3rd embodiment, so that see the structure in the passage clearly;

Figure 11 is the zoomed-in view of Figure 10;

Figure 12 is the explosive view of the utility model the 4th embodiment;

Figure 13 is the synoptic diagram that removes upper plate after Figure 12 makes up;

Figure 14 is the constitutional diagram of the utility model the 5th embodiment;

Figure 15 is the production synoptic diagram of the utility model the 6th embodiment;

Figure 16 is the synoptic diagram of the utility model the 7th embodiment;

Figure 17 is that the base material in the utility model the 4th embodiment is sheared synoptic diagram.

Embodiment

Below in conjunction with concrete accompanying drawing the utility model is described in detail.These specific embodiments only are limited the enumerating under the utility model spirit, do not get rid of one of ordinary skill in the art prior art and the utility model in conjunction with and other specific embodiments of producing.

As shown in Figure 1, the utility model pick-up unit comprises test strip 1.Test strip 1 comprises the base material of being made by hard material orsemi-rigid material 10,base material 10 comprises detection zone and makes things convenient for the district of being affectedly bashful that the user grips, and detection zone includes and can or combine and provide the detectable of detection signal with analyte reaction in the censorshipsample.Base material 10 can be by plastic sheet, the waterproof hard scraps of paper, bamboo chip, sheet metal or industry known any hard or semi-rigid materialmanufacturing.Base material 10 can be designed to different shape as required, and present embodiment is that example is illustrated with the rectangular of longitudinal.End at longitudinally ofbase material 10 is the detection zones that include reactingpad 20, then is to make things convenient for the district of being affectedly bashful that the user grips at its relative other end.For making things convenient for the user to grip pick-up unit, it is bigger than the overall size ofbase material 10 other parts to be affectedly bashful the overall size in district.

The reactingpad 20 of detection zone can be one or more, can be adsorbed with the dry chemistry reagent that detects different material on each reacting pad 20.These dry chemistry reagents are dissolved in the solvent earlier, and then reactingpad 20 is immersed in the solvent behind the certain hour airing again, and chemical reagent promptly is adsorbed on the reactingpad 20.

As shown in figure 15, the district of being affectedly bashful on thetest strip 1 forms when shearingbase material 10, and the other parts of being affectedly bashful district andbase material 10 are one.In a preferred version, on a bulk of hard or semi-rigid material,adjacent base material 10 is scaled off end to end, thereby realizes zero waste material.This design has that material usage is few, and production process is few, and production equipment is simple, is convenient to the characteristics of automated production, thereby cost is very low.As shown in Figure 2, be affectedly bashful the district and be assembled into the other end ofbase material 10 with respect to detection zone by the independent rigid plastic of making.In this design, being affectedly bashful the district isHandheld Division 30 by the plastics ejection formation.One end ofHandheld Division 30 is provided with thepassage 60 that a size andbase material 10 are complementary with respect to the size of the other end of detection zone, andbase material 10 inserts and is fixed in thepassage 60 with respect to the other end of detection zone, thereby is combined closely inbase material 10 andHandheld Division 30.

Handheld Division 30 is plastic sheets of injection mo(u)lding, and has formed above-mentionedpassage 60 in the ejection formation process.The inwall ofHandheld Division passage 60 is provided with the structure that increases its adhesion that combines with base material 10.These structures can be selected from following technical proposal: the inwall ofpassage 60 is become coarse; Inwall atpassage 60 is provided withtooth line 40; Inpassage 60, fill or coating dung (as glue, adhesive sticker, double faced adhesive tape etc.);Pinning 37 is set inpassage 60; Passage 60 is designed to shape wide outside and narrow inside, and the size of wide portion is greater than the width ofbase material 10, and the size of narrow portion is less than the width ofbase material 10, afterbase material 10inserts passages 60, and two sides ofbase material 10 andpassage 60 sidewall interference engagement.

As shown in figure 14,Handheld Division 30 can be the integrated plastic sheet of a slice, forms above-mentionedpassage 60 in injection molding process.When being provided with the tooth line in thepassage 60, the tooth line can be straight line, curve, wave of any angle etc.But whenHandheld Division 30 was the integrated plastic sheet of a slice, the bearing of trend oftooth line 40 was preferably consistent with the direction of insertion of base material 10.This design can be withdrawed from mould easily afterpassage 30 moulding.It is minimum that this design can make the cost of HandheldDivision 30 drop to.

As shown in Figure 3,Handheld Division 30 also can be the plastic sheet by two injection mo(u)ldings, and promptlyupper plate 31 andlower plate 32 combine.Upper plate 31 andlower plate 32 are respectively equipped with the structure of buckle mutually, thereby make the two in conjunction with forming Handheld Division 30.The structure of described mutual buckle is arranged on theprojection 33 and thebutton hole 34 of two opposite faces afterupper plate 31 andlower plate 32 combinations.

As shown in figure 16, in order to reduce cost, it is identical thatupper plate 31 andlower plate 32 can be designed to structure, thereby only need a mold can produceupper plate 31 and lower plate 32.Another advantage of this design is, when being assembled into HandheldDivision 30, the workman need notupper plate 31 andlower plate 32 are distinguished, also need not separate storage, workman's any two plastic sheets of taking promptly can be assembled into HandheldDivision 30, thereby avoided being similar to the problem that to distinguish left and right pin when wearing footwear, further reduced cost.In order to solve the problem thatupper plate 31 andlower plate 32 structures still can be assembled when identical,upper plate 31 is provided with twoprojections 33 and twobutton holes 34 withlower plate 32 symmetrically successively along its center line parallel withbase material 10 direction of insertion.Whenupper plate 31 andlower plate 32 assemblings, two faces withprojection 33 andbutton hole 34 are relative,projection 33 on theupper plate 31 just in time inserts thebutton hole 34 on thelower plate 32, and theprojection 33 on thelower plate 32 just in time inserts thebutton hole 34 on theupper plate 31, therebyupper plate 31 andlower plate 32 are mutually combined.In addition, twoprojections 33 can be set at one of them cornerwise two end, and twobutton holes 34 can be set at another cornerwise two ends.

Be economical with materials, HandheldDivision 30 is a hollow.In order to make HandheldDivision 30 still have enough intensity, be provided with brace rod 39 (Fig. 6) inupper plate 31 andlower plate 32 two opposite faces after combination.For improving the comfort level of being affectedly bashful ofHandheld Division 30,30 outside surface is provided with the level and smooth arc-shaped concave 65 (Fig. 3) of conveniently being affectedly bashful in the Handheld Division.The radian of level and smooth arc-shaped concave 65 is roughly suitable with people's thumb shape.The outside surface of Handheld Division can also be provided with anti-skidding salient point or tooth line.

As shown in figure 17, in order further to reduce cost,base material 10 is provided with aprojection 26 at a side of being affectedly bashful district's 25 1 ends, at its another relative side recessed 27 of being complementary of projection therewith is set then.In process of production, in position locate to be provided with a projection and corresponding recessed as long as shear the blade of base material, when theformation projection 26 ofbase material 10 1 sides, that adjacent base material adjacent side just in time forms recessed 27, thereby realize zero waste material, and do not increase production process again.Corresponding therewith, two sidewalls ofHandheld Division passage 60 are respectively equipped with and theprojection 26 ofbase material 10 sides and recessed 27 recessed 28 of being complementary and projection 29.Combine because the Handheld Division is the plastic sheet by two ejection formations, when ejection formation, forming above-mentioned recessed 28 and projection 29 is easily.When an end ofbase material 10 was placed inpassage 60, theprojection 26 on thebase material 10 just in time was placed onpassage 60 sidewalls recessed 28, recessed 27 projection 29 of just in time accommodating onpassage 60 sidewalls on thebase material 10, thereby buckle combination mutually.This design need not the outer material of glue single-candidate, and is simple in structure, easy to assembly, but in conjunction with very firm.

About test strip, the utility model is supplemented as follows.

Test strip can be the test format of differential responses principle.The test strip of for example utilizing capillary lateral flow to detect adopts " soak and read " test strip of mode, the detection test paper of perpendicular flow, or has electrochemical reaction test paper of electrode or the like.

The basic structure of lateral flow test strip comprises along the hydraulic fluid side and is followed successively by sample application zone, mark zone, detection zone, Quality Control district and unnecessary absorption of sample district to cross-wind direction.The sample that detects joins sample application zone, and this sample is vertically flowed along test paper by capillarity, and through the mark zone, if there is analyte in the sample, the specific combinating substance on this analyte and the mark zone forms compound.This compound, combines with the catches specificity through including the detection zone of catching the analyte zone along with liquid continues to flow forward, thereby compound is hunted down and accumulating at surveyed area, thus display result.Excess liquid continues to flow forward through the Quality Control district and finally is absorbed the district and absorbs.

Adopt the test strip of the mode of " soak and read " to comprise that two of " soaking " and " reading " detect step.According to different test items, the reaction reagent quilt is dry in advance to be fixed on the membrane carrier of drying chemical reagent paper.During detection, the liquid sample that need are detected directly is added on the test paper, and measured matter and the reagent generation change color that reacts is utilized detecting instrument or manually interpretation carried out in the depth variation of color, draws the qualitative or quantitative analysis result of measured object.

Vertically the vertical detection test paper comprise will have a reaction reagent the carrier mutual superposition together, top-down each reaction reagent layer of flowing through of liquid sample finally shows testing result.

The test paper material that is loaded with reaction reagent in the above-mentioned detection test paper is a kind of multiamide tunica fibrosa.Test paper can have any suitable thickness, for example, and from 0.6 to 1.0 millimeter, or from 0.8 to 1.2 millimeter, or from 0.8 to 1.0 millimeter, or from 0.9 to 1.1 millimeter.The area of one suitable thickness be 60 millimeters liquid of taking advantage of 10 millimeters multiamide tunica fibrosa can absorb 0.6gm (+/-0.15gm).Such nylon film is to obtain (for example, Filtrona Fibertec from various commercial sources^TMColonial Heights, VA).Certainly many other absorbent materials also can be used as the detection test paper.For example, utilize amine or hydroxy-acid group to add to as surfactant on the surface of fiber, also can well apply among the present invention, these are to obtain (for example, Filtrona Fibertec from various commercial source^TM).In other embodiment, cotton fiber or polyester also can be used as the detection test paper.These materials carry out pre-service according to different detection applications with washing agent, protein and damping fluid.In other method, detect test paper and can make (for example cellulosic triacetate) by nylon fiber, nitrocellulose, dacron, cellulose esters or cellulosic acetate.With reference to the present invention, can also be can be used as the detection test paper by various other the materials that those skilled in the art expect.

Electrochemical reaction test paper with electrode comprises a base plate and the hydrophilic porous material layer that is positioned on the base plate with electrode system substantially.A hydrophobic protective layer is positioned on the hydrophilic porous material layer, places overlayer at last and finish whole device on hydrophobic protective layer.

Detectable can make things convenient for means to add the detection test paper to by all, for example detects the test paper material and is immersed in oven dry then in the reagent.Another kind of mode is that reagent is added on the test paper by spraying method, perhaps the mode of serigraphy etc.

Described detectable comprise have immunoreactive specific binding molecules, based on the test agent of chemical reaction, based on biological test agent (for example enzyme or ELISA test), based on fluorometric investigation reagent, can produce the material of electron transport etc.Detectable can be used for analyte is carried out qualitative or quantitative detection.

During concentration of glucose, the detectable of selecting for use comprises glucose oxidase, hydrogen peroxidase, potassium iodide in measuring urine.When measuring the ketoboidies in the urine, the detectable of selecting for use comprises sodium nitroprusside.When measuring the cholerythrin in the urine, the detectable of selecting for use comprises 2,6-dichloro diazo salt boron fluoride hydrochlorate.When measuring in the urine leucocyte, the detectable of selecting for use comprises K-281 phenol, esterase and diazo salt.

Detected goal analysis thing can drug abuse." drug abuse " is a kind of medicine that is used for non-medical purpose (being generally used for hazy and illusionary effect) (DOA).The abuse potential of this medicine causes body ﹠ mind injury and (in some cases) dependence, habituation even death.Comprise cocaine, amphetamine, methamphetamine class, barbiturates, sedative class, lysergic acid diethylamide, tricyclic antidepressant, Hog, tetrahydrocannabinol, morphine, cocaine, heroin etc.Analyte can also be alcohol, hormonal substance, nucleic acid molecules, virulence factor, glucose, cholesterol, ketoboidies, cholerythrin, urobilinogen, nitrite, red blood cell, leucocyte etc.

The sample of analyte can be mouth cavity fluid (as " saliva "), whole blood, serum, blood plasma, urine, spinal fluid, biological extract, mucus and tissue fluid etc.

Claims (15)

1. pick-up unit, it is characterized in that: pick-up unit comprises base material, base material comprises detection zone and makes things convenient for the district of being affectedly bashful that the user grips, detection zone includes the detectable that can react or combine and provide detection signal with the analyte in the censorship sample, and the overall size of being affectedly bashful the district is bigger than the overall size of base material other parts.

2. pick-up unit according to claim 1 is characterized in that: detection zone is positioned at an end of base material, is affectedly bashful the relative other end that the district is positioned at base material.

3. pick-up unit according to claim 2 is characterized in that: be affectedly bashful the district and include the Handheld Division, the Handheld Division is attached to the other end of base material with respect to detection zone after by the hard material manufacturing again.

4. pick-up unit according to claim 3 is characterized in that: the Handheld Division is the plastic sheet of injection mo(u)lding, includes passage, and base material inserts this passage with respect to the other end of detection zone, and combines closely with vias inner walls.

5. pick-up unit according to claim 4 is characterized in that: the inwall of Handheld Division passage is provided with the structure that increases the adhesion that combines with base material.

6. pick-up unit according to claim 5 is characterized in that: these structures can be selected from following technical proposal: vias inner walls is become coarse; In vias inner walls the tooth line is set; Dung is set in passage; Pinning is set in passage; Passage is designed to shape wide outside and narrow inside, and the size of wide portion is greater than the width of base material, and the size of narrow portion is less than the width of base material, after base material inserts passage, and base material two sides and channel side wall interference engagement.

7. according to each described pick-up unit of claim 4-6, it is characterized in that: the Handheld Division is the plastic sheet of a slice injection mo(u)lding, forms above-mentioned passage in injection molding process.

8. according to each described pick-up unit of claim 4-6, it is characterized in that: the Handheld Division is that the plastic sheet by two injection mo(u)ldings combines, and two plastic sheets are respectively equipped with the structure of buckle mutually, thereby makes the two in conjunction with forming the Handheld Division.

9. pick-up unit according to claim 8 is characterized in that: the structure of described mutual buckle is arranged on the projection and the button hole of two two opposite faces after the plastic sheet combination.

10. pick-up unit according to claim 9 is characterized in that: the structure of two plastic sheets is identical, and each plastic sheet is equipped with two projections and two button holes, and the set-up mode of projection and button hole just in time projection and button hole makes mutual snap close.

11. pick-up unit according to claim 7 is characterized in that: the bearing of trend of passage inner tooth thread is consistent with the direction of insertion of base material.

12. pick-up unit according to claim 8 is characterized in that: be provided with brace rod in two opposite faces of two plastic sheets after combination.

13. pick-up unit according to claim 3 is characterized in that: the outside surface of Handheld Division is provided with the level and smooth arc-shaped concave of conveniently being affectedly bashful.

14. according to claim 3 or 13 described pick-up units, it is characterized in that: the outside surface of Handheld Division is provided with anti-skidding salient point or tooth line.

15. each described pick-up unit according to claim 9-10, it is characterized in that: base material is provided with a projection at a side of being affectedly bashful Qu Yiduan, at its another relative side recessed of being complementary of projection therewith is set then, the projection of base material one side just in time is formed at recessed of adjacent that base material adjacent side; Two sides of Handheld Division passage are respectively equipped with and the projection of base material side and recessed recessed of being complementary and projection, thus buckle combination mutually.

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