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CN1541628A - Constantly high temperature high pressure oxygen bed microwave treating device for cancer prevention and treatment - Google Patents

Constantly high temperature high pressure oxygen bed microwave treating device for cancer prevention and treatment
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CN1541628A
CN1541628ACNA031230679ACN03123067ACN1541628ACN 1541628 ACN1541628 ACN 1541628ACN A031230679 ACNA031230679 ACN A031230679ACN 03123067 ACN03123067 ACN 03123067ACN 1541628 ACN1541628 ACN 1541628A
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bed
microwave
oxygen
head
magnetron
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陈绍勇
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The thermotherapeutic cancer treating equipment consists of high temperature and high pressure oxygen bed, microwave treating unit, monitor, oxygen supplying unit, hot water supplying unit, outer breathing and beverage replenishing unit. It is used in treating cancer and can relief or cure cancer via killing cancer cell fast. It may be also used in treating hypertension, diabetes, cerebral vascular diseases, etc. It is safe, efficient and green.

Description

High constant temperature hyperbaric oxygen bed microwave cancer heat preventive and thermal therapeutical equipment
Affiliated technical field
The present invention relates to a kind ofly come equipment that the disease and the cancer of human body are prevented and treated, particularly a kind of high constant temperature hyperbaric oxygen bed microwave cancer heat preventive and thermal therapeutical equipment with microwave and hyperbaric oxygen.
Background technology
Aforementioned
One and another miracle has been created in the death that modern medicine has successfully stoped numerous disease to cause, but medical science yet is faced with an one and another difficult problem ... in worldwide, still have numerous disease threatening human life so far.
Various malignant tumor (cancer) disease and pain; According to national cancer pain on-site investigation, 62% cancer patient has pain in various degree, is increased to 70~80% to late period.The World Health Organization's statistics, the whole world has at least 5,000,000 people to be subjected to the cancer pain torment every day at present, and wherein there are 1,000,000 people in China, and many patients can't bear painful and commit suiside.A doctor who is engaged in clinical tumor got intestinal cancer old age, after transfer to bone, lung again, pain makes one to commit suicide in the several years to he who takes things philosophically.He says: " wondered why in the past that some cancer patients can but be impatient at slight illness in the face of death by calm face; oneself must be out of shape now and just know; what cancer was the most fearful is not death, but the unthinkable pain of ordinary person---not to depend merely on will with regard to patient pain." in the article according to " healthy Times " on April 3rd, 2003 relevant " cancer patient have the right to select for use narcotics ": according to statistics, the annual nearly 1,600,000 people's cancer strickens of China, 1,300,000 people die from cancer.Allow the cancer patient avoid pain and torment, become the sign of a national drug management policy and medical level.
Cancer pain has become the problem that the whole world is paid close attention to.The World Health Organization (WHO) just proposes the target of " allowing the cancer patient not bitterly in 2000 " and " three step analgesia schemes " (the oral administration mode of patient's long-term prescription is convenient in employing as far back as nineteen eighty-two, press the administration of pain degree ladder, administration on time and dose are the individuation of dosage of standard with the pain disappearance), the consumption of medical morphine as one of judgment criteria of cancer pain treatment level.Special medicine director Gu Weiping of place of security control department of National Drug Administration says: ... human society does not find the better analgesic that can replace morphine so far, morphine be the devil be again the angel, only otherwise flowing into illegal channels rationally is used on one's body the patient, just can effectively improve patient's quality of life.
In the article according to [healthy Times] on April 3rd, 2003 relevant " cancer patient have the right to select for use narcotics ": according to new " cancer patient is bid to host the regulation of narcotics personality card " that China issues not long ago, cancer patient's narcotics of will having the right suitably to select to use." cancer patient is bid to host the regulation of narcotics personality card " of a few days ago uniting issue according to National Drug Administration and Ministry of Public Health, during the medical institutions prescription, should set up complete file case history, itemized record conditions of patients, pain control situation, use nomenclature of drug and quantity, the state of an illness that takes into full account the patient needs and individual variation.The production of each special medicine, operation, applying unit, being necessary for the cancer patient provides the medicine of 80 kinds of multi-sizes to supply its selection, helps the patient to remove slight illness.According to statistics, the annual nearly 1,600,000 people's cancer strickens of China, 1,300,000 people die from cancer.Allow the cancer patient avoid pain and torment, become the sign of a national drug management policy and medical level.China does not encourage the life-time service opium analgesics traditionally always, and reason is to worry that such medicine is easy to generate drug dependence.But the expert thinks that the patients with advanced cancer analgesic need be primary, and tolerance and physical dependence occurring is normal phenomenon, seldom produces psychic dependence.It is introduced that flow into illegal channels for preventing special medicine, China medicine prison department is with the management of further standard to narcotics.
According in [Beijing Youth Daily] on March 24th, the 2003 relevant article of " principle that " cancer patient does not have pain " established ": last Sep, after " cancer patient is bid to host the regulation of narcotics personality card " formal appearance, some experts still think, allow the free anesthetics of cancer patient not have basis, but the Chinese Central Television (CCTV) newsflash has been mentioned the narcotics right to use of cancer patient once more recently.The reporter from up-to-date " bore " that national Bureau of Drugs Supervision obtains is, treats narcotics, and the cancer patient will " use of having the right suitably to select ", and clearly the regulation constituent parts must provide the medicine of 80 kinds of multi-sizes selective.In this slight news, we have seen the progress of social life once more, have seen the clear step that administration grows with each passing hour.
Cancer patient is defied dead and fear pain, and this is a well known fact.In the medical practice in the past, owing to be subjected to the influence of shortage economy environment, the suitable ubiquity of medical worker " morphine phobia " in addition, causes the too strictness of management to narcotics, all has every year a large amount of cancer patients to take leave of this world in angor.
Bitter sorrow not only allows the patient lose the dignity of life, has also deprived the peacefulness of family numbers of patients.One in certain city, the north is engaged in clinical tumor medical treatment doctor for many years, gets cancer in the time of in the evening of life, and unaffordable pain allows him commit suicide in the several years, he says, after getting cancer, why the patient who has just understood oneself can be calm in the face of dead, and can't bear pain.It is dead that former Minister of Public Health's Chen Minzhang is suffered from cancer of pancreas, and just before dying, he exhorts that specially Concord Hospital must carry out pain clinic.
Pain therapy is on China passed by one and uneven road.From requiring patient " to restrain oneself " at first, give low dose of non-opium narcotic finally, carry out " three ladders relieve the pain therapy " to nineteen ninety again, it is difficult that each step all can be rated as.1985, China added the United Nations's " Single Convention on Narcotic Drugs in 1961 ", and each contracting party of this requirements of convention realizes that in 2000 national cancer patient does not have the target of pain.Since 1999, medium such as this newspaper began to appeal to remove pain for cancer patient, and some hospices begin to occur on Beijing and other places, and a no pain is as elementary object.Up to 2002, the cancer patient did not have pain and just can be regarded as for a kind of practice guideline and determined to get off, and patient's analgesia requires can attain full and complete satisfaction finally.From showing loving care for health to showing loving care for spirit, this is that a human nature is thirsted for constantly being made widely known, the humanistic track that gos deep into public life gradually, has embodied the continuous improvement of human rights situation in China.
Cancer patient is a very little social group, still, to this crowd's care, brings progressive breath but can for our society.Realize that the cancer patient does not have the target of pain, established an important social criterion, that is exactly to respect each individual fundamental right, and it is happy to respect proprietary spirit, this has the demonstration meaning for remove " the morphine phobia " that exists on the different society aspect.
Cerebrovascular disease (apoplexy or cerebral hemorrhage); High blood pressure disease; Gastroenteritis; Influenza and pneumonia; Bronchitis (comprise emphysema gentle sound breathe heavily); Diabetes; Liver cirrhosis; Tuberculosis; Infectious disease and wound.
Acquired immune deficiency syndrome (AIDS); A kind of fatal infringement human immune system's disease can make the victim very easily suffer from the disease that human body can be resisted usually, as pneumonia, and meningitis and be called as the cancer etc. of Kaposi's sarcoma.
Medical research confirms: the blood that normal person's cerebral arteries per minute is supplied with brain is about 800ml, cerebral arteriosclerosis makes arterial lumen stop up 80% when above, the amount of blood supply wretched insufficiency, classical symptoms such as head is heavy, vexed, dizzy, headache, hypomnesis will appear in the obvious anoxia of brain!
The doctor warns you: cerebral arteriosclerosis is the arch-criminal of apoplexy! Head is heavy, vexed, dizzy, headache, hypomnesis are not aging normal phenomenon, as untimely treatment, will cause apoplexy, causes hemiplegia, aphasia, Mental Subnormality, dementia
Whole world cancer patient's general introduction
According to World Health Organization's statistics, in the whole world 6,000,000,000 populations, people 4,000 ten thousand people suffer from cancer now, wherein there are more than 700 ten thousand patients untimely and dead because for the treatment of, and increase about 9,000,000 new cancer patients every year, that is to say just had a people to be captured life by cancer every 6 seconds.And China cancered big country that is the first in the world, number is about 1,500,000, dead about 1,100,000, and along with the quickening of process of industrialization, and environmental pollution is serious day by day, and the rate of sending out of cancer has and continues the trend that rises, and disease clothes cancer is countries in the world physician's a dream, the Secretary General of World Health Organization (WHO) foretold once that capturing cancer had quite in Chinese medicine.
Annual thrombosis patient in the world has more than 4,000,000 people.Causing circulatories such as cerebral hemorrhage cause 5,300,000 people's death sick every year.In the face of the easiest causing death of cerebrovascular disease is difficult to the disease of curing again, also make millions upon millions of people stand the misery that these diseases are brought simultaneously.The ability of forfeiture effect and life.In the whole world, particularly developing country suffers from other kind cancer numbers and also will increase sharply.Prediction address says that various cancers will cause 6,300,000 people's death every year, causing circulatory such as myocardial infarction, cerebral hemorrhage is died of illness will cause 5,300,000 people's death every year, because of the number of suffering from other chronic disease death will reach 2,500,000 people every year, the three adds up to annual dead about 2,450 ten thousand people of number.The number that the man suffers from carcinoma of prostate will increase by 44%.
People generally look forward to reaching 35 years old average life before 500 years, and nowadays for a numeral has prolonged 1 times, but alive people still feels very very brief.Because the medical expert thinks that the people should live 170-200 year.Today, the life-prolonging people often thought that the success of his way to keep in good health also is right on it, but having any can not ignore more can not obliterate, that is exactly his the too busy to get away human development of success and social this integral body of making progress, and is comprising medical science and entire society in the great efforts of having done aspect death control among this.
Every disease all is to cause people's death, different just time speed, length.China's population disease death reason, the past serves as that the master now transfers three kinds of diseases to infectious disease, parasitic disease, and first is cerebrovascular, and second is heart disease, and the 3rd is malignant tumor.Also that's about the size of it in world other countries.Point out in 1997 " reports of world's health status " that World Health Organization (WHO) delivers that heart disease and cancer chronic diseases seize more than 2,400 ten thousand life every year, wherein 1,530 ten thousand people die from heart disease, and 6,300,000 people die from cancer, account for the dead population nearly half.
Data shows that cancer overall annual progressive increase rate in the world's is 3%, and wherein sickness rate tool first place is gastric cancer and pulmonary carcinoma, and its annual progressive increase rate is respectively 10.5% and 10.4%; Secondly be knot, rectal cancer, annual progressive increase rate is 9%, and the progressive increase rate of uterus carcinoma is 7.3%, and the progressive increase rate of oral cancer is 6%.The sickness rate of developed country's cancer is high more.According to statistics with regard to pathogenesis of cancer in general, the U.S. has increased by 1 training over nearly 25 years, and wherein pulmonary carcinoma has almost increased by 13 times; Japan has increased by 21% over nearly 10 years.Certainly developing country is no exception.
Show according to data that as China cancer has entered second in most residents' of province, city and region the cause of the death.Wherein Beijing, capital accounts for the tenth during nineteen fifty, rises to the 5th in 1956, has occupy first or second since 1964 always.The seriousness of problem is not so far.In the period of following 25, the national cancered number of patients of part might significantly increase in the world according to World Health Organization's prediction.By 2005, the quantity that the women suffers from pulmonary carcinoma in European Union member countries will increase by 33% from now, and the number that the man suffers from carcinoma of prostate will increase by 44%.
In the whole world, particularly developing country suffers from other kind cancer numbers and also will increase sharply.Prediction address says that various cancers will cause 6,300,000 people's death every year, causing circulatory such as myocardial infarction, cerebral hemorrhage is died of illness will cause 5,300,000 people's death every year, because of the number of suffering from other chronic disease death will reach 2,500,000 people every year, the three adds up to annual dead about 2,450 ten thousand people of number.
World War II was got to 1945 from nineteen thirty-nine always, 7 years dead fifty-five millions every year on average 7860000 altogether, and the annual dead number of cancer, cardiovascular and cerebrovascular disease and other chronic diseases goes even farther, the latter is the former 3.1 times.Common people are often frightened at the war of firearms or fearful natural disaster; 240,000 people's Tangshan Earthquake in the dust for example; put one's ass on the line financial resources, material resources and manpower goes to wage a struggle, but for the war not second to the health of the war of the smoke of gunpowder and earthquake disaster, all lacks crisis and the sense of urgency should not really.
Resolution is made by the 32nd World Health Assembly, requires United Nations member for " Fighting Disease promotes human health ", supports World Health Organization (WHO) to realize the global strategy target of " everybody enjoyed health care in 2000 ", and is the effort of realizing this goal.Simultaneously, World Health Organization (WHO) has drawn up 10 new standards, has wherein embodied the healthy physique aspect that is comprised, 3 contents of psychological aspects and social aspect.These 10 new standards are:
Each national city can obtain basic health care and the first order facility of changing the place of examination at least; The somebody of institute carries out self health care and family health care in its possible range, and actively participates in social hygiene's activity; Whole world resident group can both bear its member's health care responsibility together with government; The people have safe drinking-water and environmental sanitation equipment; The people can both obtain enough nutrition; All children can both obtain the immunity inoculation of main infectious disease.
The order of severity to 2000 of infectious disease in public health of developing country year is no more than the degree in 1980 years of developed country; Use the method for all probabilities, by the mode and the control nature of influence life, social mentality's environment prevents and controls uninfection and promotes mental health; Everybody can obtain essential drugs.Must acutely aware it also brought many new problems for society, wherein first is the general expense expenditure of astronomical figure, comprise diagnostic imaging, no profit and slight diarrhea operation, artificial organ, organ transplantation, cytokine application, genetic engineering, new medicine, new material and microcatheter technology etc., the new and high technology of using at medical field has covered each training of inside and outside woman, it is when alleviating patient's misery, giving accurately diagnosis and treatment in time, and bringing a problem the most tangible is that medical expense rises significantly.
Now in the world also almost the government of neither one country, society and family can be each member of society, be affordable high new and high technology medical care expenses.The unfavorable family of economic condition will have to abandon using new and high technology diagnosis illness, from and draw a very serious social problem; How curative activity follows principle of humanitarianism and medical services fair principle.
Face the stem reality of the growth of medical care expenses considerably beyond country, cause, business unit's ability to pay, some areas and unit have set about original labor medicare system is taked all reform measures and adaptation.Carry out medical fee and played certain positive role to cutting the waste, reduce spending with the way that the individual links up with.
But the unit that has decides worker's individual burden ratio too high in implementation process or takes without hesitation to take responsibility for one's surplus or deficits, the way that over-expense is all taken care of oneself, make some serious diseases, severe disease, chronic disease, difficult disease patient, particularly old worker's individual burden is overweight, causes the unwarranted on the contrary situation of normal medical treatment.What some workers were very worried says, our really slight flu all can not get now, and suffering from the medical fee of once catching a cold half a year or a year has not just had.Also have some workers to complain that this way is actually and has limited the worker of inefficient enterprises, retired employees, has blocked patients such as serious disease, severe disease and occupation disease, the uneven and lopsided situation of business burden of serious bitterness and happiness has appearred in its result.
Temperature and life-biological heat engineering in medicine
Liu Jing (doctor researcher Chinese Academy of Sciences low temperature center): 21 century is biological century, in fact biomedical technology has been considered to the research field in three big forward positions in this century now, one is life sciences, have first of the nanotechnology of being exactly and the information science, biomedical technology has become the forward position and the commanding elevation of development Creative Science and Technology Co. Ltd again.No matter in ten thousand li ice-bound South Pole, still in the equator that The hot sun is high in the sky, temperature is not only sensation cold and tight heat to what life brought, and synthetic and evolutionary process all plays a part very important to the metabolism of life for it.Everybody can feel comparative heat during the broiling summer, winter of cold feel to be exactly cold, the two phenomenon all follows temperature that relation is arranged in fact, Here it is biological heat medical engineering.Specifically mentioning the role of biological heat medical science in life sciences, in fact all is related with temperature.And temperature heat or cold influence to biosystem is embodied in micro-meter scale simultaneously or at nanoscale in other words conj.or perhaps, it can be at several microns to tens microns specifically to mention cell, nanoscale and for example, in fact as molecule, the molecule of biological the inside is at nanoscale; The effect of hot and cold after pair cell or the molecular action at first, is reflected to again on the macro-scale of tissue often at last thus, and the engineering background of this respect is non-constant width.
Why can human body temperature be at 37 ℃? in fact the phenomenon of temperature and life is that what to be come from extension is very widely.We know normal mammal, such as human, he can only live within the very narrow temperature range.The mankind belong to Homoiotherm, and Homoiotherm has so relational expression; Be exactly in the body heat production should equal the heat radiation of health to environment, only in this way could keep the constant of his body temperature.This also is a result who obtains through evolution of long period of time, is exactly that body temperature reaches 37 ℃ today.Specifically mention body temperature, body temperature generally refers to the body temperature in deep, and the temperature practice change of body surface is very big, and it is easy to be subjected to the influence of surrounding, generally can change between 14 ℃~20 ℃.Among each organ of human body whole body, the temperature of liver is the highest, probably at 38 ℃, all follows everybody closely related clinically.Survey body temperature clinically, mainly survey axillary fossa, oral cavity and rectum.The chances are for the temperature of rectum at 36.9 ℃~37.9 ℃, and the temperature in oral cavity is lower slightly, and the temperature of axillary fossa is minimum.Axillary fossa since measure more convenient and usefulness at most, normal person's axillary temperature generally is 36 ℃~37.2 ℃, if the temperature of surveying within this digital scope, just can have been thought normally.
Heating also has its positive meaning in fact, slight or moderate heating is the immunocompetence that helps strengthening the human body system of defense, it can improve the condition of disease power of doing, be embodied in the picture leukocytosis, cytophagous phagocytosis strengthens, and antibody generates and increases in addition, and the detoxification ability of liver is strengthened, so people also are used to artificial fever to diminish inflammation in view of the above.Also utilize heating to treat tumor even in some cases.
The high temperature biomedicine.Human some passes of coming application of temperature and human body initiatively of now having developed into tie up to the purpose of carrying out medical science, and important example of this respect is exactly a tumor thermotherapy.Thermotherapy also is for a long time far away in fact, and its history will be reviewed can just this record before B.C. 5000.In the legend, ancient Greek have a well-known doctor he once with heating to treat tumor, he had a maxim to be exactly at that time; Medicine is irremediable can use operative treatment, performs the operation irremediablely can use thermotherapy treatment, and thermotherapy is irremediable also just can't treat really.
Modern neoplastic fevers iatreusiology is to start from decades ago basically, because multi-disciplinary intervention, people begin to adopt the means of science to study the problem of relevant thermotherapy.Particularly the effect of thermotherapy merging radiotherapy, chemotherapeutic treatment tumor is beat all often.
Because find that by a large amount of zoology cell experiments the heating pair cell has direct toxic action, general cell is heated and reaches 41 ℃~45 ℃ and can keep and just can kill mammiferous tumor cell in tens of minutes, so, a basis of tumor thermotherapy that Here it is.Also having a kind of is the thermotherapy mode of whole body.We know that treatment will be very difficult when tumor development arrives whole body.It is many that chemotherapy and radiation is used at present, still, this dual mode lethal and painful be bigger.People have also been developed the general tumour thermotherapy thus.But it seems that at present it in fact also still exists a lot of problems.The way of this general tumour thermotherapy is that the blood vessel of human body the inside is taken out of, and the heater by the external world heats up to blood, and then turn back in the body and go, and treats tumor thereby by the blood that has been heated each position of human body whole body is heated.But,, will be easy to kill the tumor of body surface after being heated such as the simplest superficial tumor though thermotherapy is of great use.
But implement at human body in other words in the deep, sometimes this therapeutic effect is not can be such according to what people predicted, and in fact it is very complicated.A very important problem is arranged aspect tumor thermotherapy, is exactly the thermotherapy plan.
So-called thermotherapy plan is exactly by the human body thermotherapy is needed great power, can cause the heat effect of the many high-temperatures of human body how to develop, conveying of medicine or the like is just carried out in the conveying of temperature control medicine according to human body temperature, it is closely related that some problems are all followed science of heat like this.
At present, this subject is to scientific, standardization and quantized directions development.First kind is the thermotherapy mode of external heating.Micro-wave therapeutic is exactly the therapeutic modality of external heating, and microwave heating food is to utilize the effect of spatial field to come food is heated.Also useful ultrasound wave carries out external heating.Such as shell temperature is actually and is subjected to subcutaneous blood circulation, the metabolism of local organization, also has the heat conductivity of skin, and the temperature between skin and the environment and humidity exchange or the like restrict mutually.In addition, high temperature is high to a certain degree burning, and this in fact also is the problem that needs engineering and medical science to study simultaneously and solve.
Take passages central 10 (on October 12nd, 2002)
At present domestic and international medical science is dynamic to tumor thermotherapy research
The heat mechanism of resulted tumour blood vessel injury
After skin is heated, the increase of blood flow, to small part because vasodilation, blood capillary be subjected to vaso-active substance such as Kallidin I or histamine stimulate the back open due to.Blood heat raises heart rate is increased, and increased by heating region and systemic blood flow thereby make.
From the morphology of blood vessel, tumor vessel is different with normal blood vessels also just not at all surprising to the reaction of heat.Blood capillary in the tumor is made of monolayer endothelial cell and there is no the elastic substrates film.The part of the defective between endothelial cell also is made of tumor cell, so tumor cell can directly contact blood flow.When tumor cell when tube chamber is bred, tube chamber is blocked or influence blood flow.Tumor vessel is tortuous usually, spiral or be unexpected opisthotonos, extremely expansion.
Studies confirm that in recent years: the blood capillary system of tumor is different with normal person, and it is made up of one deck endotheliocyte, basement membrane and perithelial cells, lacks vascular smooth muscle and adventitia, and wall approaches rapid wear; Long and twist, arteriovenous anastomosis is abundant; Skewness, slow blood flow; Be in open state under the normal temperature, can not the further expansion increasing blood flow after being heated.
Someone thinks: for the tumor cell that the adapts to continuous propagation demand to nutrition, the capillary tube in the tumor is extremely expansion.Another characteristics are that the blood vessel of tumor is abundant blood sinus shape structure.The blood capillary of normal structure has only part to be open state, and tumor tissues is then different, even under normal temperature, the blood vessel in most of tumor is functional status.Because tumor vessel also is extremely expansion under normal temperature, be appreciated that therefore blood fortune can not increase when temperature raises.
The capillary tube of tumor is thinner, is difficult for adapting to the burden that the blood flow increase gives.When constituting the damage that tumor endotheliocyte capillaceous or oncocyte are subjected to heat, blood will spill blood vessel from its gap.Owing to causing blood flow, the hemorrhage capillary pressure rapid drawdown meeting that causes stagnates.Except angiorrhexis, hemorheological change also is the reason of tumor vessel obturation of being heated.The erythrocyte hardening also can be blocked blood capillary in addition, and leukocyte is attached to blood vessel wall also can the occluding vascular passage.
Neural sensor is unsound, to the reactionless ability of epinephrine, can not correspondingly regulate with variation of temperature; The cancerous protuberance growth is rapid in addition, normal easily the carrying out property regression of vascular bed, and the blood flow that causes many tissues is than the obvious minimizing of normal structure.
But when heating, along with the rising of temperature, normal blood vessels can be expanded voluntarily, and flow increases, suitably heat radiation, and the blood vessel in the cancerous tissue then easily causes blood flow stagnation in the tumor based on These characteristics, and heat radiation is slowed down, and temperature raises.Researcher is found already, tumor is more normally organized more responsive to the variation of its living environment, at first, cancerous cell more is afraid of " heat " than normal cell, just dead easily under 41~43 ℃ high temperature, this also is the theoretical basis that adopts method treatment tumors such as radiotherapy, chemotherapy, thermotherapy, microwave, laser.Studies show that though when beginning heating back, tumor all had increase with Normocellular blood flow, the former increase can not show a candle to the latter, and it is preceding below horizontal to be reduced to heating in the heating back regular hour again rapidly.Normal structure heating bleeding from anus flow rate than the high 2.5-30 of tumor tissues doubly.Tumor and normal structure heat respectively 41 ℃, 42 1 hour, blood flow occurs and stagnate, recover can recover normal blood flow behind the normal temperature.But 43 ℃, the 47 ℃ rewarmings again after 1 hour of heating respectively, then blood flow no longer returns to normally.
Find in the experiment that temperature is optionally destroyed tumor vessel during greater than 43.5 ℃, normal blood vessels then is without prejudice.Thermal environment impels anaerobism sugar decomposition rate rising in the cancer in addition, lactic acid produces and increases, partial pressure of oxygen and pH value descend, cause the interior environment of tumor to present acid state, improved the sensitivity of cancerous cell to temperature, influence the propagation of tumor cell and synthesizing of DNA, RNA, this is another foundation of gastrointestinal cancer postoperative intraperitoneal perfusion therapy.
A kind of gene is arranged on the cancerous cell, specialize in to the required albumen of cancerous cell, if closed this gene, then cancerous cell will be dead.
Neoplastic fevers iatreusiology basis
Heating also has its positive meaning in fact, slight or moderate heating is the popularity that helps strengthening the human body system of defense, it can disease resistance enhancemen, be embodied in the picture leukocytosis, cytophagous phagocytosis strengthens, and antibody generates and increases in addition, and the detoxification ability of liver is strengthened, so people also are used to artificial fever to diminish inflammation in view of the above.The high temperature biomedicine, important example of this respect is exactly a tumor thermotherapy.Because find that by a large amount of zoology cell experiments the heating pair cell has direct toxic action, general cell is heated and reaches 41 ℃~45 ℃ and can keep and just can kill mammiferous tumor cell in tens of minutes, so, a basis of tumor thermotherapy that Here it is.
Thermotherapy also is for a long time far away in fact, and the work that its history will be reviewed can just have this record before B.C. 5000.In the legend, ancient Greek have a well-known doctor he once with heating to treat tumor, he had a maxim to be exactly at that time; Medicine is irremediable can use operative treatment, performs the operation irremediablely can use thermotherapy treatment, and thermotherapy is irremediable also just can't treat really.
Modern neoplastic fevers iatreusiology is to start from decades ago basically, because multi-disciplinary intervention, people begin to adopt the means of science to study the problem of relevant thermotherapy.Particularly the effect of thermotherapy merging radiotherapy, chemotherapeutic treatment tumor is beat all often.
Also having a kind of is the thermotherapy mode of whole body.We know that treatment will be very difficult when tumor development arrives whole body.It is many that chemotherapy and radiation is used at present, still, this dual mode lethal and painful be bigger, people have also been developed the general tumour thermotherapy thus.
But it seems that at present it in fact also still exists a lot of problems.Though thermotherapy is of great use, will be easy to kill the tumor of body surface after being heated such as the simplest superficial tumor.But implement at human body in other words in the deep, sometimes this therapeutic effect is not can be such according to what people predicted, and in fact it is very complicated.A very important problem is arranged aspect tumor thermotherapy, is exactly the thermotherapy plan.So-called thermotherapy plan is exactly by the human body thermotherapy being needed great power, can causing the heat effect of the many high-temperatures of human body.
Conveying of medicine or the like is just carried out in the conveying of temperature control medicine according to human body temperature, it is closely related that some problems are all followed science of heat like this.
Temperature is heat in other words conj.or perhaps, and the influence of biosystem is embodied in micro-meter scale or simultaneously at nanoscale, and it can be at several microns to tens microns specifically to mention cell, nanoscale and for example, and in fact as molecule, the molecule of biological the inside is at nanoscale; The effect of hot and cold after pair cell or the molecular action at first, is reflected to again on the macro-scale of tissue often at last thus, and the engineering background of this respect is non-constant width.Why can human body temperature be at 37 ℃? we know normal mammal, such as human, he can only live within the very narrow temperature range.The mankind belong to Homoiotherm.Homoiotherm has a relational expression; Be exactly in the body heat production should equal the heat radiation of health to environment, only in this way could keep the constant of his body temperature, be exactly 37 ℃ that body temperature reaches today.
Body temperature generally refers to the body temperature in deep, and the temperature practice change of body surface is very large, and it is easy to be subjected to the influence of surrounding, generally can change between 14 ℃~20 ℃.Among each organ of human body whole body, the temperature of liver is the highest, greatly about 38 ℃.Survey body temperature clinically, mainly survey axillary fossa, oral cavity and rectum.Generally at 36.9 ℃~37.9 ℃, the temperature in oral cavity is lower slightly for the temperature of rectum, and the temperature of axillary fossa is minimum.Normal person's axillary temperature is generally at 36 ℃~37.2 ℃.Such as shell temperature is actually and is subjected to subcutaneous blood circulation, the metabolism of local organization, also has the heat conductivity of skin, and the temperature between skin and the environment and humidity exchange or the like restrict mutually.
The relation of the temperature and time during thermotherapy
Thermotherapy temperature in the time of 41 ℃~43 ℃ to the tissue not damaged
The mankind belong to Homoiotherm, and body temperature is exactly 37 ℃ that reach today
Well-known heating can make the permeability of blood flow increase in the blood vessel, vasodilation, blood vessel increase.The Pathophysiology of the normal structure blood vessel that heat causes sexually revises relevant with temperature and action time, overheatedly blood vessel is damaged cause tissue necrosis.The blood flow that it should be noted that " normally " tissue by tumor is usually greater than the normal structure away from tumor.
Temperature and the mutual relation between heat time heating time have been done many researchs to various biosystems during about thermotherapy.Existing evidence shows, no matter is exsomatize system or living systems, temperature and all have logarithmic relationship between heat time heating time.What this relation can both have been drawn together is expressed as: for effect being controlled at same level, and more than 43 ℃ the time, 1 ℃ of the every reduction of temperature, need double heat time heating time; Below 43 ℃ the time, 1 ℃ of the every reduction of temperature need increase by 2~4 times heat time heating time.Between time and temperature, given same effect is identical logarithmic relationship.
The skin that Henrigues (nineteen forty-seven) has observed people and pig is expressed the required different temperatures-time combination of damage that reaches certain one-level simultaneously to 44~52 ℃ reaction.Every increase can make reduce by half action time for 1 ℃.Human skin and Swine seemingly, for example: make the Corii Sus domestica skin reach 44 ℃, 420 minutes (7 hours) of the downright bad needs of complete epithelium; And the people is 360 minutes (6 hours).When temperature was 45 ℃, people and pig all reduced to 180 minutes (3 hours); In the time of 47 ℃, the people is 30 minutes, and pig is 45 minutes.In theory simple heating process is that the temperature transition phase is extremely short, and keeps the temperature constant of phase.Another may be that cell has the ability of the heat sensitivity of adjusting own with the closely-related factor of heat tolerance.When cell adapted lower Normal Environmental Temperature, this relative temperature just reduces.
Heat shock response
Heat shock response can not only be induced by the hot injury, and be many other impairment factors and stress stimulation, comprise physics, chemistry and mechanical stimulus, induce as factors such as ischemia, anoxia, cold, wound, poisoning, free radical, hunger, heavy metal and glucose shortages.Heat shock protein plays an important role to the self stability of keeping body as a kind of stress protein that high conservative is arranged during evolution.
Heat shock protein 70 change of Expression before and after the osteosarcoma thermotherapy
The quantity of osteosarcoma tissue expression HSP70 increases behind the microwave heat therapeutic, but submission osteosarcoma specific antigen is given the T cell, activates the immune system of body, thereby improves the antineoplastic immunization of body.Tumor cell can bring out body's immunological function after thermotherapy, the attack again of homology tumor is had protective effect, and normal cell carries out unprotect effect after the same processing, shows the effect of the raising body antitumor specific immune function of thermotherapy.
Studies show that (heat-shockprein HSP) 70 is bringing into play important effect to heat shock protein in tumour immunity.
We have reduced the rate of transform after osteosarcoma patient row microwave heat therapeutic is protected the limb operation.Improved survival rate.
HSP70 expresses the research that reaches with the immunologic function relation after the osteosarcoma cell thermotherapy but still have nothing to do at present.Simultaneously, after different temperatures and time thermotherapy, the HSP70 increasing expression still is not reported at body osteosarcoma and osteosarcoma cell line.
The people can bear 41.8 ℃ of a few hours
The physician utilizes this difference of normal cell and cancerous cell just, and the temperature of " artificial hyperpyrexia " is strict controlled between 41 ℃~45 ℃.Be in the cancerous cell of this state, at first, the speed of its ingestion of glucose slows down greatly, and the speed of growth also slows down with regard to corresponding; Secondly, its division must be carried out in slightly alkaline environment, and has increased the acidity of cell after the heating, has directly hindered the division of DNA (DNA (deoxyribonucleic acid)); The 3rd, hyperpyrexia also makes the required B23 protein of cancerous cell synthetic DNA significantly reduce, thereby suppresses and even blocked the synthetic of DNA, accelerates its dead speed.On the contrary, for eliminating and control focus cell and cancerous cell have been created advantageous conditions.
The normal temperature of skin is lower about 3 ℃ than body temperature
The touch upon data of heat tolerance of major part is meant skin in the document.People often think it is so to know from experience at least, and skin can be represented the reaction of normal structure to the reaction of heat.Be far from being literally true as preceding pointing out.The normal temperature of skin is lower several times than body temperature.
For example, the body temperature of mice often is 31~32 ℃ and skin temperature is 28 ℃ under anesthesia.
It is usually more responsive to heat to have adapted to the cell that compares under the low temperature environment.Skin can be represented this situation to the reaction of heat, if heat with water-bath, the temperature of skin will be higher than the temperature of tumor.
Usually heat with ultrasonic or electromagnetic wave during clinical treatment, be aided with surface cool again and make the skin cooling, suitably improve the following temperature of skin thereby can improve power without water-bath.
Normal structure increases by 2 ℃ to the toleration of heat
Because skin cooling event skin injury commonly used is less, fat, the muscle Chang Buneng of its below cooled off and damaged when microwave heat therapeutic.Fatty tissue specific heat is low in addition, blood circulation is poor, poor thermal conduction, and the muscle fat interface causes fat overheated to factors such as electromagnetic reflections.
The lineup of Stanford university (nineteen eighty-three) fatty tissue and muscular tissue all can be seen heat tolerance.Heat tolerance can make normal structure that the toleration of heat is increased by 2 ℃.Though (this damage mostly occurs more than 46 ℃) can appear in the complication of fibrosis and deep layer abscess when thermotherapy, at 45 ℃, 30 minutes, serious fibrosis and abscess should not take place.
Some tumor vessel is just collapse in the time of 41 ℃
Can tumor optionally be heated or optionally sustain damage actually and blood flow can have been taken away substantial connection to how many heats from normal structure or tumor tissues.Blood flow reduces most of tumors 41~43 ℃, 30~60 minutes the time heating.Even some tumor vessel has just collapsed in the time of 41 ℃.The blood flow of (SD rat) increases by 8~10 times 43~45 ℃ the time heating.
The Wistar rat is heated, and dermal blood flow increases by 20 times 43 ℃ the time.Blood vessel in some normal structure is worked as 46 ℃ and still is kept perfectly.
Can expect that little tumor easily for blood cooling cool in the health, is difficult for reaching intensification.
It is the key factor that influence the tumor healing that the antigenicity of tumor, the tumor blood flow amount that causes after heating change.
Whether evenly also most important by the heating region temperature, be very difficult and reach this point.
41.5~42.0 ℃ temperature just can be destroyed tumor tissues fully
The hot injury of different tissues and cell is different.If in the time of keeping certain high temperature within 15~20 hours, the someone reports 41.5~42.0 ℃ temperature, just can destroy tumor tissues fully.Add the effect that temperature therapy and X ray and gamma-rays and time spent can promise oneself and multiply each other.
42 ℃~45 ℃ " high temperature " can kill cancerous cell
The Basic of Biology of at present relevant tumor thermotherapy is established.Nobody can suspection can kill cancerous cell with 42 ℃~45 ℃ " high temperature " now, cures some experimental tumor and human tumor.The sort ofly think that malignant tumor is that the also rare people of viewpoint of the contraindication of thermotherapy (naturopathy) has talked.Heating merges with radiation uses the radiosensitivity that can increase tumor, and the effect that strengthens radiotherapy also obtains the confirmation of a large amount of laboratorys and clinical research again and again.Synergism between heating and some chemotherapeutics also is that a large amount of laboratory datas confirms.
Thermotherapy can be cured 43 ℃ of cancer pieces of tumor large stretch of significantly coagulation necrosis
The statement of facts thermotherapy can be cured tumor.Lot of documents is reported in recent ten years, and thermotherapy merges the curative effect that radiotherapy can obviously improve tumor.Solid tumor nearly 30%~50% is in original place recurrence or metastases in local lymph node after the radiotherapy.Abroad, domestic great mass of data shows:
1. cell is to high temp. sensitive;
2. can increase high temperature when tumor is in low pH environment to the killing of tumor cell,
3.S the cell of phase is the most responsive to high temperature, but relatively radiation is resisted;
4. blood circulation is different with normal structure in the tumor, produces the heat accumulation phenomenon in the posterior tuberosity of heating, and formation temperature is poor;
5. at high temperature ray pair cell killing action increases, and the effect of some chemotherapeutics also strengthens, and produces synergism.Bigeminy or three treatments might improve curative effect.Data shows that thermotherapy has potentiation to radiotherapy, and heat strengthens than between 1.1~1.4.If can just can reduce sequela at a specified future date with lower dosage control tumor for pediatric tumor.Whole-body hyperthermia is used for the treatment of whole body to be shifted.It might be used for the treatment of (or merging other therapies) potential metastasis or micro metastasis.When the tumor temperature reaches 50 ℃, for contiguous heart and trunk and harmless.With hydro-thermal rubber blanket parcel limbs, prevent the skin heat radiation.The reduction wave frequency can increase the penetration depth to tissue, adopts the multi radiator cross-fire, can be with bigger energy focusing in the deep tumor district.Specimens from pri shows that heating reaches that person's tumor piece has large stretch of significantly coagulation necrosis more than 43 ℃.
Adopt hot radiotherapy that whole pathological changes is obtained than effectively heating and less radiological dose reach therapeutic purposes uniformly.Clinical practice shows that these patients are benefited really, and it is better to appease effect.Also be used for the head people that cures the disease gradually, really can improve survival rate.
The central nervous system can not see damage for 42 ℃
With the micro-wave therapeutic central nerve neuroma very big potentiality are arranged.With the Stanford university headed by the Britt, they carry out 50 minutes heating with ultrasonic dura mater through cat to brain after opening cranium.When being higher than 42.5 ℃, temperature can produce acute injury.These pathological changes sharpness of border comprise the white matter edema, neuron is downright bad and loses (44~45 ℃), myelin destruction.Visible coagulation necrosis in the time of 47 ℃.In neuron dissolving more than 43 ℃.Think that irreversible damage threshold should be 42.5 ℃, 50~60 minutes.(nineteen sixties) such as early stage Harris, dabbling research showed that also 42 ℃ be can not see damage to dog heat, obvious damage was arranged, i.e. edema, localized bleeding and thromboembolism more than 44 ℃.Observe clinically, the electroencephalogram physiological changed when whole body was heated.Think and cause that at 41.8~42 ℃ the change on the function is reversible.Heat itself to the damage of normal structure when minimum foot killed tumor.
Thermotherapy can be cured tumor or tumor is dwindled, but does not cause normal tissue injury recent and at a specified future date.The host makes medium thermal dose also can eliminate tumor to the effect of tumor.Here should consider the factor of host's immune function and local blood circulation.Unquestionable, immunoreation is regulated and will be played an important role to the treatment of experimental tumor and even the treatment of human tumor.
Nant (1975) comments and thinks: to treating effective patient 40~41 ℃ heating is arranged all.But the effective degree of patient is not proportionate with the degree of generating heat.During (Dickson1977) report treatment primary tumor, along with primary tumor disappears, metastatic tumour dwindles thereupon.Local warming cures than the whole body easier tumor that makes of heating.Local warming does not increase the rate of transform or promotes tumor growth.Heating in 43 ℃, 90 minutes to make primary tumo(u)r and metastatic tumor all be suppressed.Unsuitable heating do not promote the growth of metastatic tumor or primary tumo(u)r yet.
43 ℃ of thermotherapies can not influence protein synthesis
Evolutionary process provides heat-flash stability protein to thermophilic bacteria.Can not think that the needs of evolving make mammalian cell select the enzyme of thermal resistance, therefore, at contiguous 50 ℃ or slightly under the low temperature, the enzyme in mammal source is not that degeneration impossible take place.The enzymatic activity of adjusting biosynthesis speed is subjected to gradient of temperature and changes, but different enzymes is different certainly.
Thermokinetics argument and many other experimental datas all illustrate, one or more protein are the cell key compositions when heating.Though have several to studies show that heat 43 ℃ or higher temperature, protein synthesis almost completely suppressed.Confirm that some times after cell is got back to 37 ℃, protein synthesis restarts but these researchs are also clear, its speed near in addition surpass the not matched group of heating.
Protein or protein synthesis
Evolutionary process provides heat-flash stability protein to thermophilic bacteria.Can not think that the needs of evolving make mammalian cell select the enzyme of thermal resistance, therefore, at contiguous 50 ℃ or slightly under the low temperature, the enzyme in mammal source is not that degeneration impossible take place.
The enzymatic activity of adjusting biosynthesis speed is subjected to gradient of temperature and changes, but different enzyme is different certainly.Thermokinetics argument and many other experimental datas all illustrate, one or more protein are the cell key compositions when heating.Though have several to studies show that heat 43 ℃ or higher temperature, protein synthesis almost completely suppressed.Confirm that some times after cell is got back to 37 ℃, protein synthesis restarts but these researchs are also clear, its speed near in addition surpass the not matched group of heating.
It is synthetic can not influence RNA and RNA below 43 ℃
In 43~47 ℃ of scopes, RNA itself can not be " target " that causes cell death.But more than 47 ℃, the destruction of specific RNA may be relevant therewith.The conclusion that can draw from this research is: heat and can disturb some specific part of ribosomal RNA.
43 ℃ of heating lysosome membranes, and then the activity of increase lysosomal enzyme,
And increase lysosomal total quantity
Dna molecular itself is unlikely to be the target of thermal inactivation.The external fusing point of DNA will inactivation in one second time in less than at this temperature mammalian cell greatly about 87 ℃.Certainly other damage (not enough fusing point far away is serious like that) to DNA also can cause the cell deactivation.
As the target that few of evidence explanation DNA itself is the hot injury, there also do not have what evidence to relate to DNA to be synthetic.Even now, cell DNA is synthetic after heating obviously reduces.This inhibition is reversible, gets back at cell that DNA is synthetic within the normal temperature several hours begins again, but aggregate velocity has reduction slightly.General opinion adds the heat affecting lysosome membrane, and then increases the activity of lysosomal enzyme, and increases lysosomal total quantity.Many reports show: antibacterial can change their film component in external variation of ambient temperature procedure of adaptation.These films change the variation that has thermal resistance simultaneously concurrently.At least RNA or it synthetic in 43~47 ℃ of scopes, or DNA itself or the synthetic of it all can not be hot lethal " targets ", but temperature must consider to relate to the probability of some nucleic acid when higher.
Heat tolerance is an important phenomenon, and its generation comprises two processes at least, the first, and temperature dependency (between 42.5~43 ℃); Second process needs protein synthesis, and what relate to is that overall protein matter is synthetic or specified protein is synthetic, in the at present positive research.
" microwave therapy " can promote synthesizing of DNA (DNA (deoxyribonucleic acid))
The organ for inheritance of " microwave thermotherapy " pair cell also can the generation effect.The organ for inheritance of microwave pair cell also can the generation effect, comprising the short-term training of strengthening ribonucleic acid.For example, behind the cerebral cortex with the microwave radiation mouse, the content of its ribonucleic acid increases by 60% than non-irradiation mouse.On the other hand, microwave radiation can protect organ for inheritance to make it not to be subjected to the effect of ionizing radiation.For example, use earlier neutron, reuse microwave radiation cell culture medium.Generally, neutron can be in gene and chromosome mutagenesis, the mutagenesis of neutron promptly can stop behind the microwave radiation.Research thinks that the reason that this effect produces has promoted the biosynthesis of DNA DNA (deoxyribonucleic acid) just because of microwave radiation.When especially microwave radiation was in human body fluid, blood viscosity lowering strengthened the human-body biological membrane permeability effectively, make blood circulation happy, arteries recovers elasticity, can effectively prevent the formation of hypertension, cerebral hemorrhage, cerebral thrombosis, reduces the generation of angina pectoris, myocardial infarction.
It is very good that chemotherapy and thermotherapy merge effect
After entering the sixties, the someone begins to attempt tumor is merged chemotherapy with thermotherapy.The Italian doctor Cavaliere that is worth mentioning in 1967 annual reports behind blocking-up femoral artery and the femoral vein, method with the extracorporeal circulation isolated organ perfusion is poured into patient's limbs with blood heating back, and osteosarcoma, synovial sarcoma and the melanoma etc. of treatment lower limb obtain comparatively satisfied curative effect.Over 20 years, Cavaliere and his colleagues are engaged in this work always and make progress, and this is the extraordinary example of an explanation thermotherapy effect.
Experiment proves with clinical observation: but microwave anticancer synthetic DNA
But microwave anticancer synthetic DNA (DNA (deoxyribonucleic acid)) slows down its reproductive process, and then kill cancer cell, and injuring normal cell not.Microwave irradiation people tumor of the throat and hepatoma are observed the non-deadly form that these two kinds of cell strains all occur in various degree and are changed, and this experiment provides microwave can make oncocyte that the morphologic basis of damage takes place.The microwave irradiation inhibitory action that growth has to mice S-180 sarcoma, electron microscopic observation show that irradiation mouse tumor cell is most of downright bad, and the matched group oncocyte is biological good, divides vigorous.Illustrate that microwave radiation has than the obvious direct killing effect oncocyte.The mice animal experiment finds, with Co60 and the compound irradiation of microwave, the CFU-C growth of bone marrow cells in mice had facilitation.In radiotherapy, implement micro-wave therapeutic, not only enhanced sensitivity is obvious, and the radiation injury of hemopoietic function is had the effect that promotes recovery.At chemotherapeutic period, implement micro-wave therapeutic, demonstrate inspirer effect.Hematoporphyrin derivative (HpD) in conjunction with microwave irradiation, proves people's tumor cytotoxicity effect: HpD adds the mmW treatment.The oncocyte mortality rate obviously improves, and reaches 90%, and uses HpD merely, and the oncocyte mortality rate is 21%.
In a word, microwave can suppress and kill cancer cell effectively, and cooperation is put, chemotherapy can improve curative effect, and promoting leucocytes is accelerated the recovery of impaired organ, improves patient's life quality.
At present, the heating means that can adopt are a lot, as ultrasonic, microwave, medicinal liquid or blood heating perfusion etc.If the deep layer cancerous protuberance can also take to imbed in vivo miniature antenna to receive the method for microwave heating.Research shows that also hyperthermia and medicine, radiotherapy use simultaneously, can strengthen medicine and radiation effect.Especially some is in the DNA cancerous cell of synthesis stage, often owing to the insensitive destiny of being destroyed of escaping of lonizing radiation is survived.Yet hyperthermia is the strongest to the lethality of these " fish that has escape the net " exactly.So the three joins with fighting, and can learn from other's strong points to offset one's weaknesses, receive significant more effect.
" microwave thermotherapy " of Japan
It is a kind of from external heating method to the body interior cancer that microwave electromagnetic waves is heated.Insert electrode at the position that cancer is arranged, feed electromagnetic waves (traumatic microwave) such as microwave, RF ripple betwixt.Because body surface has also become the condition of high temperature, so will come to be the skin cooling with cold water or cold wind.Although known the fact of cancerous cell poor heat resistance very early, thermotherapy does not still have extensive use.Reason is also not establish correctly measures method of temperature in the body, and only the heating of cancer nests position is shown up 42 ℃ and also also have certain difficulty.
The whole body heating is used extracorporeal circulation and is returned in the body after blood being heated to about 45 ℃ external again, is applicable to the cancer patient that shifts of whole body.But this method complexity will be subjected to the restriction of many situations, has implemented certain difficulty.The local heat method uses hot water, electromagnetic wave, laser etc. only in the affected part local heat, is a kind of simpler method.Hot water method is applied to early stage bladder cancer, and laser is applied to early gastric cancer through endoscopic catheters.
Subclinical kitchen range is not eliminated, and will cause the treatment failure
So-called subclinical kitchen range is meant with general method of clinical analysis and can not finds, the focus that naked eyes also be can't see.This focus usually be positioned at the tumor main body around or remote part; Sometimes the character that belongs to multiple kitchen range.For example breast carcinoma about 20.2%.About multiple kitchen range is arranged; When and for example the clinical examination axillary lymph of breast carcinoma was become feminine gender, having approximately performs the operation more than 10% confirmed to have lymphatic metastasis.Some clinical tumor inspection is a limitation, has hematogenous metastasis, but clinical being difficult to finds find to shift, this never means it is the consequence of topical therapeutic after treatment.Do not eliminated as subclinical kitchen range, certainly will be caused the patient's of suitable big figure treatment failure.
Still can not measure subclinical kitchen range at present, can only treat by clinical rule, have certain blindness, therefore the research of subclinical kitchen range is a major issue of tumor research.
The treatment of a success should be not only to have healed the sick but also preserve patient's function.
Heating induced tumor Study of apoptosis
The later stage eighties, immunologic studies have shown that, therefore the cell mortality is a kind of process of optionally removing id reaction T cell in thymus, in the formation of self tolerance with prevent to have important function in the generation of autoimmune disease.The tectology inspection finds that the process of these id reactions T cells exclude has typical apoptotic characteristics.Obviously, if this apoptotic process is obstructed, the eliminating of id reaction T cell just not exclusively, consequently produces autoimmune disease.Like this, cell physiological death, promptly apoptosis just has been endowed the meaning of particular importance.
As if people recognize suddenly how former life sciences has only paid attention to cell " work ", and ignored how " extremely " of nature of cell thereby the research of having lost " second half " of life.Because life itself is exactly the dead unity of opposites.Since the nineties, the research of cell carcinogenesis has been pulled to the forward position of life sciences quickly, has formed the research climax that almost relates to biomedical every field.Consequently in short several years, with regard to the morphology of pair cell apoptosis, the biochemical variation in the cell, the gene of modulating apoptosis, and cause apoptotic various factors and all accumulated a large amount of data with relation of some diseases or the like.These have all impacted the traditional view to the generation of disease consumingly.
Apoptosis research is to have enlarged space of thinking to the promotion of modern medicine maximum, has understood to give birth to and be the cells physiological feature extremely all, and they all have identical importance to body normal physiological function and interior environment stable; Not only the process of " life " of cell and " work " gets muddled and can cause disease, and it is the reason that disease produces too that the normal death process of cell is obstructed.
Apoptosis research provides new direction for the research tumor.Apoptosis Mechanism tool in the pathogenesis of tumor has certain effect.From the viewpoint of system, the generation of malignant tumor and growth not only be to break up this key element by cell division to cause, and the cell death key element may also relate to wherein.When dead the new cell that studies show that also have its path of control, and in malignant tumor, the dead path of cell may be suppressed, and causes cell survival to prolong.Malignant tumor cell apoptosis research not only has positive effect to understanding tumor invasion mechanism, and significant aspect oncotherapy and prognostic evaluation.
The prognosis of tumor and the cyto-dynamics of tumor have substantial connection, and the cyto-dynamics balance of tumor is kept jointly by cell proliferation and apoptosis.Therefore, the activity of research apoptosis of tumor cells, can judge for the prognosis of tumor provides new clue.Heating induced tumor apoptosis is for the thermotherapy of tumor provides theoretical foundation.
Thermotherapy and oxygen supplement and the nanometer adjustable hematopoietic stem cell of infusing
In the past thirty years, in the nearly all biology course, all can talk about this content of stem cell.Teacher can tell you: people's cell is from bone marrow, and stem cell is an immature cell in the bone marrow, and all hemocytees all produce from stem cell.Regrettably, this but is a huge misunderstanding.In decades, biologists are puzzled to stem cell always.They can't extract stem cell from bone marrow, also just can not see " distinguished face " of stem cell certainly.Frankness says that some the evidence that exists about stem cell was indirect purely in the past.But, this sorry existing finish, the scientist of Stanford Univ USA and Australian imperial Melbourne hospital through 30 years concentrate on studies, has found this stem cell finally.Researcheres are shouted and jumped for joy, and they take pride in for the achievement that obtains in separating the purification stem-cell research themselves.Because this achievement will make bone marrow transplantation become safety with simple, has brought the dawn of wishing for treatment of diseases such as cancer patient, radiation sickness, hemophilia and anemia.
Hematopoietic stem cell is the germinal cell that generates hemocyte, and they play an important role in keeping the activity of hemopoietic throughout one's life.Any reason causes the variation of hematopoietic stem cell, will bring serious harm to health.The purpose of research hemopoietic stem cell proliferation, differentiation and regulation and control is the generting machanism of final clarified blood cell, and is hemopathic diagnosis, and treatment provides the theoretical foundation of science.The control of the adjusting of intravital hemopoietic active receiving cell and multiple factors such as cell, cell and environment and neuro humor.Exist hematopoietic cell in the hemopoietic tissue and non-hematopoietic cell two classes are split into branch, the latter is except playing the support effect hematopoietic cell, also by local condition the propagation and the differentiation of hematopoietic cell played special influence.This except that hematopoietic cell all participate in the regulation and control hemopoietic between the matter composition, comprise blood capillary system, nerve, skein cell, substrate and other connective tissues, be referred to as hematopoieticmicroenviron-ment.
Hematopoieticmicroenviron-ment may directly contact with hematopoietic cell or discharge some factor, influences or induce the physiological activity of hematopoietic cell, and some external factor such as ray, medicine or anoxia etc. also may influence the activity of hematopoietic cell by hematopoieticmicroenviron-ment.Also exist many active factors of hemopoietic that influence in the body, wherein existing stimulus object also has mortifier, they by a whole set of tight feedback mechanism to hematopoiesis up to regulating and control action.
Studies show that in recent years, apoptosis are the active processes of a Gene regulation, are the physiological mechanisms of cells in vivo quantity regulating.The apoptotic factor that starts often comes from the cell or extracellular dead signal, start some gene transfer relevant and translation through a series of signal transmission (comprising a plurality of links such as information conduction, gene expression, albumen synthesize), thereby cause the synthetic of novel protein with cell death.Many genes participate in (comprising oncogene, antioncogene and viral gene) adjusting of this process.Some scientists think then the more intravital factor of not knowing as yet of people determines how many each hemocytees needs to guarantee a people's health best.How to influence the destiny of stem cell if can find these factors, OK will be an extremely valuable medical discovery.
" microwave thermotherapy " can regulate and control " viscosity of cell "
The viscosity of " microwave thermotherapy " energy regulating cell reaches the order ground that cures all kinds of diseases.Scientist wishes can stop the metastasis of cancer, cure arthritis and all kinds of disease by the control of pair cell viscosity.If cell does not have viscosity, people will as the motley fruit jelly in a stand stand spill wolf nationality everywhere, cell is always followed a biological prerequisite fortunately, can be sticked together, and makes us that the various bodily forms, life normally be arranged.When cell was not followed this prerequisite, our life will be in danger.If the cell adhesion is too tight or too loose, tremulous pulse will get clogged, and cancerous cell can cruise on the whole body, and perhaps some position of health will inflammation or inflammation aggravation.Think through inventor's research, adopt the viscosity of " human body ecological balance-energy is newly ruled by law and treated tumor " may command cell, just can obtain a series of the effectively Therapeutic Method of wound.
The organ for inheritance of microwave pair cell also can the generation effect
The organ for inheritance of microwave pair cell also can the generation effect, comprising the short-term training of strengthening ribonucleic acid.For example, behind the cerebral cortex with the microwave radiation mouse, the content of its ribonucleic acid increases by 60% than non-radiative mouse.On the other hand, microwave radiation can protect organ for inheritance to make it not to be subjected to the effect of ionizing radiation.For example, use earlier neutron, reuse microwave radiation cell culture medium.Generally, neutron can be in gene and chromosome mutagenesis, the mutagenesis of neutron promptly can stop behind the microwave radiation.Research thinks that the reason that this effect produces has promoted the biosynthesis of DNA (deoxyribonucleic acid) just because of microwave radiation.When especially microwave radiation was in human body fluid, blood viscosity lowering strengthened the human-body biological membrane permeability effectively, make blood circulation happy, arteries recovers elasticity, can effectively prevent the formation of hypertension, cerebral hemorrhage, cerebral thrombosis, reduces the generation of angina pectoris, myocardial infarction.If carry out health therapy before sleeping, conduce to sleep, health care is calmed the nerves.
Microwave can excite and can suppress cell activity
Microwave " biology excites "---utilize the microwave of thermophilic power can cure wound and reduce infection.
Accurately can not the thinking of the effect of micro-wave therapeutic anticipated, and achievement in research in recent years might be explained some mysterious part of this material.Studies show that microwave can excite and can suppress cell activity.As if this peculiar effect depend on the wavelength and the intensity of microwave.
These cells comprise lymphocyte and macrophage (these two kinds of cells all participate in immunoreation), and the fibroblast of working in wound healing.Studies show that the radiation of microwave, thermophilic can both excite these cells at short notice, heavy dose of, long-term irradiation then can suppress even kill these cells.The radiation dose that excites or suppress cell becomes with wavelength.
Micro-wave therapeutic is exactly breathing and the metabolism that influences cell.Microwave can activate the chemical substance relevant with the Cellular respiration mode, comprising NADA (nicotinamide adenine dinucleotide), dehydrogenase and cytochrome C oxidase.The radiation of low dosage can be by a series of molecular excitation cell activity in the cell membrane, and the radiation of higher dosage then can cause damage.
The microwave electromagnetic radiation cell that can also excite nerve, and can make macrophage and lymphocyte produce a series of chemical substances that concerning the cell of other types, have the signal effect.Aspect the research of cell, be will observe the microwave electromagnetic radiation to some site, i.e. a part of effect of body.For example, this sees through wound surface to the microwave electromagnetic radiant energy of finding much wavelength, and the microwave energy of which frequency band rise this curative effect cause close important.As very few therapy of many our weak points, micro-wave therapeutic also needs to carry out careful research.
The current whole world is being 41 ℃~43 ℃ all
Following temperature is added in the human body on the tumor focus and struggles!
Hot Procarbazium prospect is tempting
The physician notices that very early some cancer patient is after having experienced a Secondary cases hyperpyrexia, and cancerous protuberance has disappeared unexpectedly miraculously.This expects them, control cancer with the way of artificial manufacturing hyperpyrexia? the origin of a kind of cancer method of controlling-hyperthermia generation newly that Here it is.
The touch upon report of the first-elected Busch in 1866 of reliable document that hyperpyrexia can tumor of west.He narrated an example be positioned at face, through the malignant tumor that the histology confirms, infect the back tumor regression at twice erysipelas.
Generate heat a few days more than 40 ℃ after Bruns report in 1884 one example melanoma in late period infects erysipelas, later tumor disappears entirely, survives 8 years.Afterwards, the case of report spontaneous regression of tumor in the Rohdenbury review of literature in 1918, in 166 routine cancers, 72 examples once had hyperpyrexia, severe infections or with the history of thermotherapy; In the 26 routine sarcomas, 19 examples once had heating, infected history.These facts all point out hyperpyrexia to play some effect to oncotherapy.【1】
A few years ago, the American physician Lay is tieed up on zooperal basis, with microwave diathermanously treat pulmonary carcinoma, colon cancer, patient's lump dwindles as a result, doing well,improving, survival rate increases substantially.Equally, the Stirling doctor of Joseph of Arimathea, Saint husband hospital is injected into blood and the cancer therapy drug through heating on one's body the melanoma patients together, last patient's 5 annual survival rates bring up to 77% from 22% of conventional method quickly, wherein have many people also to survive more than 10 years!
Is what reason this? originally, the only growth temperature of human body cell was 37 ℃, no matter was higher or lower than this temperature, all can disturb its metabolic mechanism.But, normal cell and cancerous cell are also inconsistent to the tolerance of heat, and the former can reach 45%, and the latter has only 41%.Because, after normal cell is heated, can distribute heat rapidly by means such as vasodilation, blood flow acceleration, do not allow it accumulate and work the mischief.Cancerous cell is then different, and it does not have own fixed feeder vessels, in case be heated, dyschezia, finally causes being badly damaged and destroying so internal temperature continues height with timely heat radiation.
Cancer " thermotherapy " progress
In the latter stage sixties, research, application and the development that microwave heating is controlled cancer begins to be subjected to the concern of multinational tumor educational circles, its application:
One, be to treat tumor with microwave hyperthermia to 41 ℃-44 ℃ of degree of median dose;
Two, be with heavy dose of microwave hyperthermia reach 60 ℃~more than 100 ℃, direct heat is coagulated and the cutting tumor tissues.Webb proves with laser spectral analysis, tumor cell is different to the absorption of microwave with normal cell, because the tumor tissues water content is than normal structure height, cancerous cell contains more bound water, can absorb more microwave energy, this may be cancerous cell than normal cell to one of more responsive reason of microwave radiation.50~200, the absorption of the microwave of 000MHZ is different because of kind to frequency for Foster meaning tumor tissues; Can but do not absorbed by the frequency normal cell that tumor cell absorbs, this may be because tumor cell and the metabolic difference of normal cell, so tumor tissues is higher than normal structure to the absorption of microwave energy, makes the projecting tissue of its temperature.Giovonella is under same temperature, and than normal cell sensitivity, 42.5 ℃ act on 2 hours to tumor cell to high-temperature damage, but kill tumor cell 95% only is 43% to normal cell.Hyperpyrexia breathing capable of inhibiting cell strengthens the cell non-oxidation, and this effect is obvious to tumor cell, and is little to normal impact cell, thereby tumor cell acidity is increased, and the lysosome increased activity causes cell injury.
Microwave radiation can kill leukemic cancerous cell, makes that treatment is this not to have the disease of specific short to expose dawn so far.According to one's analysis, this may be because after microwave radiation can radiation, make the cause of emitting active acid after the cancerous cell activation.The microwave radiation of intensity can not can damage human body like this.Though different tumor cells is to the sensitivity difference of temperature, in 42 ℃~43 ℃ degree scopes, the heat sensitivity of tumor cell is fairly obvious.To most of normal structures, be safe below 45 degree.
The complexity that tumor heats up is relevant with the size of tumor, and tumor is big more, because weak heat-dissipating is easy to heat up., be easy to be heated to more than 45 ℃ more than 5 centimetres the time as diameter of tumor, too little tumor is difficult to heat on the contrary.Steves thinks that tumor size and maximum intramural invasion influence, and are positioned within the 50% maximum specific absorption rate as far as possible by radiating tumor limit.
Separately the microwave irradiation therapy malignant tumor is not very good to the patient's that has therapeutic effect, controls the cancer method and can obtain better curative effect but be aided with other.Its mechanism may be:
1, high temperature makes tumor cell to radiation sensitization.Experiment showed, that lonizing radiation are very insensitive to S phase cell, can obviously improve curative effect so the two share;
2, the tumor cell that reduces radiation injury is repaired power (mainly being the reparation of G0 phase cell DNA damage);
3, alleviate the toxic reaction of body high dose radiotherapy;
4, increase the cytotoxicity of some antitumor drug.
The someone reports that the photosensitive treatment tumor of combined with hyperthermia also has synergism in addition, because microwave can excite the blood porphin drench to produce singlet oxygen, thereby it is downright bad that oncocyte is poisoned, and high temperature can suppress the reparation of the cancerous cell damage that photodynamics causes simultaneously.
Onishi United microwave thermotherapy and interferon therapy tumor, result show that the antitumaous effect of associating use is apparently higher than independent use.
Microwave is different from that electricity coagulates, the heat or the cold conductive process of laser, freezing damage to tissue, causes organizing nearly therapeutic apparatus section damage heavy, and person far away is then light.And micro-wave therapeutic needs only in radiation field, and the damage of same tissue almost is consistent.
" microwave thermotherapy " treatment " cancer "
Basic research shows: microwave radiation can be absorbed and change into heat energy rapidly behind cancerous tissue, when the cancerous protuberance district is warmed to 41.5 ℃~43 ℃, gets final product the synthetic of anticancer nucleic acid, causes cancer cell death.Simultaneously, heating can make the active increase of lysosome in the cancerous cell slurry, produces new lysosome, makes cancerous cell produce irreversible breaking-up.
" microwave thermotherapy " but kill cancer cell.Behind " microwave " radiation doses, just can kill tumor cell (clinically tumor cell being killed apogeny just is considered as killing), cause the destruction of the virus and the antibacterial entire PLA.Normal structure around the tumor can not come to harm simultaneously.Especially to middle and advanced stage can't excision tumor, can obtain curative effect and life quality preferably.Most humans does not need can treat in hospital, so patient can take like a shot.What is more important, " microwave thermotherapy " can be used to aim at healthy people and carry out the prevention and health care physical therapy, make it exempt to suffer from various diseases or cancer all the life.
Studies show that, utilize the thermogenetic effect of microwave, it is merged with chemotherapy or radiotherapy use, can strengthen chemotherapy or the radiotherapy lethal effect to tumor cell, the growth of anticancer reaches the purpose of effecting a radical cure malignant tumor or improving patient's clinical symptoms.Clinical research also proves, adopts the many benign diseases of micro-wave therapeutic, can improve symptom even healing fully.Microwave must be affirmed fully at its therapeutic effect of application of each subject of clinical medicine.
All struggling for 41 ℃~temperature below 43 ℃ is added on the focus in the current whole world
From the impetus of development, the number that tumor thermotherapy research is engaged in countries in the world increases gradually, and the tumor of treatment also relates to the tumor of multiple different parts from shallow to deeply, and the method for treatment is also perfect gradually.Because progress of science and technology, modern electronic technology has been applied to thermal diagnosis and tumor heating technique, believe in the important tumor center in the world in this century and all will set up tumor thermotherapy research center and even tumor thermotherapy section, tumor thermotherapy will obtain generally generally acknowledging, become a kind of conventional means of oncotherapy.
The current problem that presses for solution most should be how temperature to be added up, promptly can a certain internal organs heat relatively uniformly and reach below 41~43 ℃ near the serious or nonvolatil damage of normal structure meanwhile not causing again at required deep tissue of heating.In fact this is an ideal target for this, is again a difficulty, not readily accessible target.Almost at present all thermotherapy biologists and technical specialist are struggling towards this target.Difficulty at first is exactly the inhomogeneities of tissue.Human body is by various organizational compositions such as skin, fat, muscle, skeleton, lungs, and their specific heat, electrical conductivity, dielectric constant, heat conductivity, blood circulation (blood flow) are all inequality, even the profile of human body, profile all can influence the deep layer heating.
The thermotherapy of showing shallow tumor adds radiotherapy and can reach the enhancing radiotherapeutic effect, reduces the effect of radiotherapy dosage, clinical difficult checking.
The thermotherapy of deep tumor, the thermotherapy document of relevant in recent years urinary system, digestive system carcinoma increases gradually, as the esophageal carcinoma, bladder cancer, official's neck cancer of China, the bladder cancer of Japan, the esophageal carcinoma etc.
Whole-body hyperthermia is only carried out in the medical institutions of world's a few countries, and object of study mostly is the patient that late period, whole body extensively shifted.Many in conjunction with chemotherapy during treatment, some cases have been received good tumor regression effect, die but also have because of the treatment complication causes death.
The there be limited evidence currently of people carries out whole-body hyperthermia to the case that does not shift as yet the part.Whole-body hyperthermia might reduce the immunocompetence of human body, and this also is one of restriction.Be understood that heating can make the lethal effect of some drugs pair cell strengthen.For example, can expect that any cytotoxicity that not influenced by enzyme or permeability of cell membrane all will be followed the Arrhenjus law, i.e. the increase of rate constant more or less is exponential relationship with temperature.In fact, this kind form (as nitrourea) is promptly followed in the effect of several drugs pair cell.The medicine that influenced by permeability of cell membrane improves the back medicine in temperature and also enters in the cell easily, because most material can strengthen at temperature rising permeability.Lacking under the additional situation of additional energy, how does high temperature continue to kill cell? temperature is increased to clinical significant warming therapeutic temperature from 37 ℃, and the mean kinetic energy of cellular elements only has a small amount of rising.For example, temperature raises 6 ℃ and approximately only is equivalent to each molecule mean kinetic energy increase by 2%.Yet so little energy variation is enough to cause the huge change of many biochemical reaction speed.
In sum, the various tumors of thermotherapy treatment are expected to have the report of how perspective system further investigation after the several years, so the whole world has a lot of people and scientific research institution to study in recent years.To a certain extent tumor thermotherapy whether can be healthy, develop the effort of not depending on biologist and clinical scholar and depending on physicist and engineering expert rapidly.At present, this " biological heat engineering in medicine " subject is to scientific, standardization and quantized directions development.
The simple and easy hyperbaric oxygenation treatment of the U.S.
Making controls oneself, and to be in pressure state be the part good thing sometimes.People can not believe, through once novel hyperbaric oxygenation treatment, and always good so fast of wound.Bad luck in 1991 is arrived, and a fearful traffic accident makes gram Bill from the following general paralysis of cervical region, and as the people that much can not walk about, his both feet are felt to press painful very soon, and through the various treatments more than 2 years, he is notified to want amputation through pipe.I really lose both feet and both legs possibly, and this is the part major issue, and certainly, this all is the same to anyone, especially to me.But gram Bill has kept both feet and both legs, and what he leaned on is exactly this novel hyperbaric oxygenation treatment.
Since mid-term in 19th century, people's oxygen supply pressurization in case makes it concentrated, and this chest is known as " hyperbaric cabin ", and people find that first it can help bends patient's deep-sea diver's rehabilitation.Your every suction inside once can suck 6 times of oxygen to usual amount.Oxygen is actually the in-vivo tissue that is squeezed into you, and this can help the diver to recover.
Novel hyperbaric oxygenation therapy, nearest this method is found and can helps wound healing.Ma Delin doctor (U.S.) says: when carrying out to hyperbaric oxygentherapy, intravital oxygen can be pressurized to certain degree, will impel the generation of chemical reaction, and can not occur under this Therapeutic Method that is reflected at other, roughly come to this at present.
Ma Delin doctor prove, and is always all not good simply greatly.All place the hyperbaric cabin of the large-scale costliness among the high pressure different with the sort of whole body that allows.What she adopted is that partial high pressure is given oxygen therapy, and just very usual plastic bag of usefulness is used in the wound circumference position, and by the oxygen pressurization to the wound circumference position, these free radicals can be destroyed.Ma Delin doctor think, cicatrizes a wound to relate to three problems;
1. lack blood supply;
2. its free radical of discharging out can the kill tissues cell, will stop vessel growth like this;
3. wound has repeatedly injured tendency, and this will cause too many scar tissue.
Our health can produce deleterious molecule, i.e. free radical by nature.They can stop the regeneration of tissue and blood vessel, and by the oxygen pressurization to the wound circumference position, these harmful free radicals can be destroyed.Here definite oxygen supply pressure is will have very much, and the too high meeting of pressure causes oxygen intoxication, and too low meeting survives free radical.In fact, before damaged cell does not obtain good blood supply, just allow their contact oxygen, can cause repeated infection.We have found the narrow amplitude of correct pressurization, in this amplitude, can make the cardiovascular growth, cicatrize a wound and preventing from scar.Gram Bill say; Treatment is pain not at all, does not have uncomfortable sensation during treatment.Generally through onetime 4 hours treatment, it is very good that wound will heal, and gram Bill has kept both feet and both legs, and what he leaned on is exactly this novel hyperbaric oxygenation treatment.I do not feel and believe that this is genuine.
At present, reach the pressurization of suitable oxygen, depend on to the greatest extent to the greatest extent and judge and experience, in order to obtain scientific methods, the Ma Delin doctor westwards the three ancient cooking vessel government test chambers in Mo Xike continent seek certain help.Novel hyperbaric oxygenation Therapeutic Method, just as the general data of senior middle school's level, and the project in the higher-level robot test chamber not too.But this easy armarium but makes the hyperbaric oxygenation treatment walk out hospital, has stepped into family.Help the hyperbaric oxygenation treatment to become a safety and execute real system easily, this is a crucial step.Induction apparatus is used to measure the oxygen pressure in the cover, and is current, and the Ma Delin doctor can only be with the pressure of feeling to measure oxygen of finger.
Ma Delin doctor believe, her hyperbaric oxygenation therapy can help the wound healing that much uses conventional treatments to cure, thereby reduced thousands of patients' misery.At present, there is amputation case more than 70,000 every year in the U.S., and we think that this technology can reduce by patient's amputation of 90%.
Invent in order to treat bends under water diver with respiratory organ recently in the superpressure cabin.This is a kind of owing to returning the hunch phenomenon that the too fast air pressure flip-flop of the water surface causes.The superpressure cabin can make the diver change by air pressure slowly, and the diving safety is improved greatly, the floating water surface of going up of safety.
The superpressure cabin can provide hyperbaric oxygenation treatment, from knife injury with burn to diseases such as diabetes and amyotrophy.The oxygen that the wound obtains is many more, and what just heal entirely is fast more.
" microwave ultrasound " has " sonochemistry " effect
We know, chemistry be the research material composition, structure, character with and the science of Changing Pattern.The variation of material is the chemical reaction of material in other words, is the result of the energy of certain form to the material effect.Such as: carbamide is a kind of very important chemical fertilizer.It is to react synthetic by carbon dioxide and ammonia under 200 ℃ high temperature.Here it is, and heat energy is facilitated chemical reaction.An or perhaps thermochemical simple example.Only a kind of form of energy, photochemically reactive example also is very widely in our life.Such as take a picture, shutter resembles looks once the clothing honor of dodging you and has been clapped.This be because moment exposure, make a kind of photoactive substance that is called Silver monobromide on the egative film that the cause of decomposition reaction take place.We were familiar with photosynthesis especially in addition.Under the effect of sunlight, plant becomes starch and cellulose to carbon dioxide and water, and then is processed into food material.Equally, electric energy also can cause chemical reaction.Under the effect of two electrodes, water will resolve into hydrogen and oxygen.Seen above-mentioned situation, we are not difficult to expect, the content of Here it is electrochemical research.
Sound wave also is a kind of form of energy.So under the effect of sound wave, can chemical reaction take place? and form sonochemistry thus? in fact, as far back as the twenties in 20th century, just observing ultrasound wave at the chemical laboratory of U.S. Puleston university has the two potassio sulfuric acid ester hydrolysis of acceleration, and the effect of sulfurous acid reduction potassium iodate reaction.To the fifties, also once had about action of ultrasonic waves the waterishlogging research paper of separating estranged is delivered.On-11 days April 8 of nineteen sixty-eight, first world " sonochemistry " academic discussion is held in Britain Wa Weike university.This indicates that " sonochemistry " be a dark horse as a new frontier branch of science.
After three days, April 14 nineteen sixty-eight just, Britain's " safe I scholar's newspaper " report: " a new industrial revolution in the offering, it will make plastics, the traditional biological technology of the agent of washing one's face and rinsing one's mouth, pharmacy and agriculture chemistry is taken on an entirely new look.Its impayable advantage is exactly that it is safe and cheap.It does not require the high temperature and high pressure condition in the existing production, and the energy of consumes least only, and Here it is is called as acoustochemical new subscience "." sonochemistry " reaction is the result of acoustic wave energy effect.And the effect of sound wave realizes by the acoustic cavitation process.In order to explain that better what is " acoustic cavitation ", now look at following experiment.
Chen Weizhong professor (doctoral advisor, acoustic investigation institute of Nanjing University) says: " sonoluminescence " named in this test that we did.Sonoluminescence is a new phenomenon, and there is a little air bubble its inside, after ultrasound suspending is realized in the liquid the inside, it is positioned on the wave amplitude of a standing wave.Then, it can carry out very violent compression afterwards to add ultrasound wave, and after the compression, volume also can be compressed into 106 powers doubly.It is in one-period the inside, and the times of the overwhelming majority are all expanding, can only have seldom in a flash in compression, on time and space, energy has improved 1012 powers doubly altogether.Therefore just very low ultrasonic energy can be directly changed into the energy of light.
This is the device of a typical energy from mechanical wave direction electromagnetic wave conversion.Here what does not all have, and has only common air, and under High Temperature High Pressure, it can send light.This is our the common phenomenon that can't see.
Present laboratory facilities allow us comprehensively to understand the motion of cavitation bubble.It is found that it was spheric basically before breaking, its radius is along with the variation of sound wave is trembleed synchronously, and when negative pressure, bubble slowly expands.
Bubble is by partial compression when supercharging.The time of air bubble expansion and compression is asymmetric.We can say that the most of the time bubble of almost determining is to expand, compression time and of short duration, this just makes the height of the temperature anomaly of this bubble the inside.
We know, exert pressure for the container of a sealing and compress, and this will resemble the inflator that uses in our life.External force continues work done, if compression is very fast, external work almost all is converted into the content of gas in this container, and causes the temperature of gas to rise.And usually beat tin compression ratio be about 10: 1.And the volume compression ratio of cavitation bubble is about 1000: 1.
We can see usually, when compression, can heat up, such as, will heat up when we inflate to bicycle with inflator, but can not rise so highly.The temperature here can be raised to more than tens thousand of degree at least, because want air ionization luminous, it must be more than 30,000 degree.International Theoretical Calculation shows, can be up to 107 side's degree (can reach the temperature on sun surface).The probability whether fusion is arranged, these all are the problems of discussing in the world.Up to the present, its high temperature, high pressure can be applied to the treatment field of chemistry, biology and human tumor.Such as, be applied to chemically, can make the carrying out chemical reaction fast that is difficult to carry out chemical reaction.We are applied on the biology, can excise certain a part of unwanted thing.Because its high temperature and general high temperature are different.Its high temperature is localized regions of elevated temperature, and temperature is very high in the bubble, and outer some temperature of bubble all do not have.So, generally all be to be difficult to realize to its such temperature difference.But, also has only the temperature of room temperature on the limit of its bubble as its inside Da Wandu of bubble.This is to be difficult to realize, it is delicate also just here.
Any science and technology development all can produce tremendous influence to the production of society.The research of acoustic current chemical laboratory has accumulated many achievements, is just waiting in expectation to industrial conversion.We believe, described as the about Times of button: " ultrasound wave rearranges molecule by synthetic, decomposition, and control crystal structure etc. creates novel substance; estimate that these new materials cause surprising leap in the technical field of 21 century, will lay the foundation for the new technical development of many-side ".Sonochemistry will have a flourish rosy prospect at medical domain!
Kill tumor softly
This is a technology advanced in the world, when the director Franklin of DKFZ of California, USA university Mace doctor comes China's special trip to investigate " focus ultrasonic thermal therapeutic apparatus ", sends sincere gasp in admiratioing, gives very high evaluation.Developed countries such as current America and Europe have started with from gene to tumor treatment and have sought the endogenous cause of ill of morbidity, and the entity treatment of tumor is focused on " focus ultrasonic thermal therapeutic apparatus ", think that this top technology will have breakthrough help comprehensively to the entity treatment of tumor.
The advantage of focus ultrasonic thermal therapeutic apparatus is fairly obvious; 1, hemorrhage, the pain and the wound of operation have been exempted; 2, eliminate plantation and the transfer that focus can have been avoided tumor cell because of the original place; 3, be applicable to pelvic cavity, Intraabdominal entity tumor.
The focus ultrasonic thermal therapeutic apparatus is by focusing on, send the high-power ultrasonics of hundreds of Shu Zhixiang inside of human body tumors, be coupled through aqueous medium, certain of input tumor entity inside a bit, make its temperature moment reach 80~120 ℃, in 0.1~0.25 second time, make degeneration, the necrosis of tumor cell generation irreversibility, reach the purpose of treatment tumor.For many tumor patients, not operating on, under the situation of no pain, in-vivo tumour being annihilated on the spot, be undoubtedly a kind of safer, more effective Therapeutic Method, believe that the focus ultrasonic thermal therapeutic apparatus can bring the light of brand-new happiness to tumor patient.Select from: March 5 2003 the 1739th phase of newspaper digest
The electromagnetotherapy of the U.S.-apoplexy
This looks like primary Therapeutic Method, but a kind of administration's light of hope can be provided for stroke patient.Up to now, 68 years old if wooden Clarke can only be walked under the help of clamping plate, he is accepting the new therapy that a kind of utmost point advances now.This method is to redistribute patient's brain function, replaces by the brain function in apoplexy infringement zone with healthy brain region.
During treatment, on patient's lower limb, place top electrode, connect a solenoid on his head, can stimulate slightly,, also do not need other people help if nowadays wooden Clarke can better walk at partial nerve end that apoplexy is survived by coil.Research worker wishes their technology is further improved, and the beginning uses a kind of automatic clamping plate to help brain to relearn the extremity that use paralysis.If wooden Clarke is relearning walking, for such patient, this technology provides the hope of comprehensive rehabilitation.This technology also is in commitment now, and people wish can begin to carry out more clinical experiment in 1 year.
The up-to-date therapy of cerebrovascular disease of the brave research of inventor Chen Shao
Chen Shaoyong thinks through a large amount of research and clinical observation: medicine is irremediable can use operative treatment, perform the operation and irremediablely can use radiotherapy in the treatment, radiotherapy is irremediable can use gene therapy, gene is irremediable can use thermotherapy treatment, and thermotherapy is irremediable also just can't treat really.
Will carry out 3 one month courses of treatment of infusion treatment the October in the brave original because cerebrovascular disease of inventor Chen Shao every year in hospital, more than 5000 yuan.Treat oneself head with " a kind of improved microwave therapy apparatus " of the present invention the October calendar year 2001 and 2002, output 950W, treat altogether 6 times, each 30 minutes, temperature is controlled at below 40 ℃, and having adopted patented technology oxygen supplement cover, radiation head begins to perspire at 15 minutes occiputs of radiation apart from 10~15 centimeters.The treatment back is not dizzy, brains becomes clear-headed, in high spirits, has good memory, sleeps.The phenomenon that physiological function disorders such as headache, fidgety, mentally deranged, hypomnesis occur.Treatment cost amounts to about 100 yuan.Just in this case, my what calendar year 2001 has been declared 19 patented technologies, successively researchs and develops out 10 patented technologies again in 2002~2003 years, works every day and never has a rest in the middle of 16 hours.
From top said, although there is scientific research to show that cellular radiation causes heating up near once Celsius in the human body brain.But the inventor thinks that with experiment this is impossible after deliberation.The frequency of mobile phone is 900~1,800 million, and power belongs to microwave range about 1 watt.If the power of mobile phone is enough big, also can only make the position of face's armrest machine have the phenomenon of heating to occur slightly, because the mobile influence of face's ambient air, the temperature of face rises not come up in fact, and the temperature in the brain is raise 1 ℃.If mobile phone is to the influential words of head; The one, the epidermis of face has been carried out blood circulation promoting and blood stasis dispelling; The 2nd, cerebrovascular has been carried out the treatment of mediation.Can not occur so-called to brain cell cause the damage and relevant to diseases such as cerebroma, epilepsy, Parkinson's disease, hypomnesis, insomnias.On the contrary, diseases such as microwave energy treatment cerebrovascular disease and cerebroma, epilepsy, Parkinson's disease, hypomnesis, insomnia.
Inventor Chen Shao bravely adds the research for the treatment of the cerebrovascular disease of oneself with the oxygen supplement cover with 950W microwave thermal ray, as long as confirmed the radiating heat ray of microwave electromagnetic again the temperature of human body is no more than 43 ℃, and is harmless to the human body beneficial! Mobile phone might not injure human brain!
Red blood flow
For animal, there is not red blood just can't survive.Hemoglobin red in the blood earns a bare living by absorbing and transporting oxygen.Redness is the color of blood, and blood is the basic of life.Chlorophyll has just produced when iron atom in the haemoglobin molecule and magnesium atom exchange.Plant carries out photosynthesis by chlorophyll and produces oxygen, and without any a kind of animal, comprises that we are human oneself can leave green plants and their waste gas and survive.Three primary colors is called out and is sent color, also constructs life, is coincidence or business is arranged in addition, and profoundness wherein probably has only the divine force that created the universe, and person oneself can know.
The blood circulation system
Our blood circulation system transports three kinds of passengers; Erythrocyte, leukocyte and platelet.It is to be generated by our medullary cell for a platelet.Platelet and erythrocyte have accounted for 45% of our blood, and remaining is a serum.Isolated serum is xanchromatic liquid, contains 90% water and 10% chemical substance.On one point inside the blood, 5,000,000 erythrocyte are arranged, 7000 leukocytes and 250,000 platelet, there are about 5 liters of blood in our body-internal-circulation, the erythrocyte that is carrying oxygen and some carbon dioxide is suspending in serum and is flowing forward, leukocyte is responsible for and the disease operation, and slight platelet then helps our blood clotting.
Blood and blood circulation
They look that looking like softish garden coils erythrocyte, they can be out of shape shrinks by tiny blood vessel, fortunately, erythrocytic task is exactly bodily tissue and the organ of the oxygen delivery of pulmonary to us, the erythrocyte of but cutting of saying is exactly a sack that single haemoglobin molecule is arranged, and we can breathe by their bodily tissues exactly.
At first, our bodily tissue needs oxygen in the middle of the air that we breathe, and our lungs fill with air the time, oxygen and airborne other constituent just accumulate in the alveolar, in case carbon dioxide is discharged, just have been full of oxygen at every turn.Form erythrocytic hemoglobin cell, contain iron atom in these cells, in the time of their ingresss of air, these iron atoms are just oxidized, and they have absorbed oxygen, and erythrocyte is caught oxygen by this process of oxidation.
Erythrocyte is arranged in the blood, also have platelet.Platelet is very useful, see have here so a lot of.It helps the blood coagulation of wound platelet, so just can bleed by stop.Problem is the shortage platelet of being born with some man day.So they are in a single day injured will the danger of losing blood.That is to say, they than usual the people lose blood and want many many.
Is how about erythrocyte a circulation in tissue and organ?
A pump is arranged in the organ, is exactly heart.The blood that contains oxidation enters left atrium, and left atrium shrinks, and blood just enters left ventricle, and left ventricle is also shunk, and just here is compressed in tissue and the organ by blood vessel.The erythrocyte delivering oxygen is also collected carbon dioxide, and blood is got back to heart and entered into right atrium then, and right atrium shrinks, and blood enters right ventricle.Here, blood is compressed to pulmonary, and erythrocyte had been fully loaded with oxygen again after carbon dioxide was discharged.Then, the blood that contains oxygen is inhaled into left atrium again, enters left ventricle.When we moved, heartbeat quickened, and muscle needs more than usual oxygen.So, must carry more oxygen to muscle.
Want delivering oxygen just to need ferrum, in our the various food, approximately will absorb 10 milligrams ferrum every day, the needs of this just enough human body.Human body only needs 1 milligram every day, other all being stored or being excreted.
Leukocyte can secrete toxin and antibacterial is struggled when the temperature rise of blood vessel expander
If the human body fever may be a wound infection, what's this all about? a thermoregulator is all arranged in our each human body, and in general temperature is to be adjusted in 37 ℃, can reach and this temperature will produce heat.Our food can bring heat to cell, performs physical exercises also can produce heat.But what so temperature will be very fast surpasses 37 ℃, so, we just need regulate the temperature of our health to reach balance by excretory mode, this is very simple, and these can both make the heat of health discharge to evaporate, also have juice, reach last body temperature balance.
In the time of the temperature rise of blood vessel expander, leukocyte can be struggled with antibacterial, they secrete toxin, cause thermoregulator to get muddled, therefore body temperature rise, need keep balance by draining to 39 ℃, very fast in this case breathing will be rapid, and the method for solution is exactly to avoid making the too fast of temperature rising with medicine.If body temperature also rises, you will beat and shiver, and muscle contraction also is in order to produce heat, and body temperature then can go out juice when descending, and you will make temperature recovery to 37 ℃ by going out juice, when body temperature remains on 37 ℃, just brain can feel very easily.
The nanoparticle kill cancer cell
By the microgranule of these new material structures of matter and chemical property, new material can produce the effect that some we are familiar with already, makes us find the usage of renewal thanks to nanotechnology simultaneously.This liquid containing oxygen ferrum is that new material association produces.Its special nature is used for the treatment of cancer at Bai Lin now.
The biologist of especially big of An Deli Si Qiaodan professor (DyAndyeas Joydan-biologist) Bai Linchali out-patient department, for many years always famous dictum in seeking new cancer treatment method.Unexpected things in 1989 have changed his idea.When using a kind of liquid of cultivating from Sha Buluo to test, he notices that the ferric oxide particles of nanometer size has absorbed lot of energy.This cancer expert has to use the old-fashioned electromotor of a sixties owing to lack of capital, and except using on-off control, this machine can also produce intensive mutual magnetic field, the thing that real shock it is at this moment to have taken place.Researcheres have been shocked by intensive reflection, and that destructive just blast makes Jordon try to be coated with the old way that adopts the treatment tumor again.
A new material has been found, and it can heat cancerous cell by so-called high thermal process.
The ferrum oxide crystal is greatly about 10 nanometer sizes, topped the special parcel made from nanotechnology, and cancerous cell is very urgent goes for this new parcel, can see that at microscopically dark-coloured cancerous cell has absorbed nanoparticle.Jordon has used a simple experiment to prove this point, if you are with a Magnet process cell, their can be to the same direction towards magnetic field of compass.
The inventor has confirmed also that through a large amount of research microorganism and some sick cells all have magnetotaxis.This characteristic is very crucial and important with the killing microwave cancerous cell time.
This Therapeutic Method that rediscovers is used for the treatment of cerebroma.Cerebroma is fatal often, and Jordon says that in case inject to patient, nearly all nanoparticle will be concentrated at once near tumor.If patient is in the very strong mutual magnetic field, cancerous cell can be heated between 43 ℃-46 ℃, thereby is killed by high temperature.We just can prove in zoopery in the past that cancerous cell can be eliminated by high temperature.Be transplanted to mouse tumor on one's body, just by the elimination of success, be also not have new tumor longer after some months, and in this case, we have killed 44% tumor of testing mouse fully with this new technique.The high hot idea of uncle's woods scientists is to the hope of the reality of a healing of those Patients with Brain Tumors that are difficult for having an operation.First is educated device for human mutual magnetic field of preparing and peace and will come into operation soon.Some other uncommon molecules also can change under medicine and new material technology.
The inventor is being used for the prevention of medical science and is treating that through a large amount of research following characteristic is arranged to the microwave electromagnetic heat ray
Microwave is the very high electromagnetic wave of frequency, and it has a series of characteristics that are different from the common radio ripple, and all the situation with the common radio frequency range is different to make used transmission line, element, device and measuring device.Microwave technology has become the individual branches of radiotechnics.
The microwave communication technology was come out the thirties in this century.The microwave energy heating technique was invented the end of the forties, and nineteen forty-seven, first dining car microwave oven appearred in the U.S., and the ripe ray technology of microwave is really in medically application, then was the high-tech new technique of the hot topic of just rising in the eighties in this century.Microwave has following characteristics: wavelength is very short, and frequency is very high, has like light characteristic; Delay effect in circuit, kelvin effect, radiation effect etc. generally all show significantly; Can penetrate ionosphere.Communicate everybody with " microwave " and all be familiar with and understanding, with microwave TV signal is sent to huge numbers of families such as television station, various radars, communication equipment all be unable to do without microwave technology.Microwave is the same with radio wave, infrared ray, ultraviolet and visible light to be electromagnetic wave all, is present in our daily living space.
Microwave is electromagnetic a kind of.It has and the visible light similar performance.It also is 300,000 kilometers of per seconds in the speed of spatial transmission, can reflect and reflect, and also can focus on.The wavelength of general microwave is between 1 millimeter to 1 meter, and frequency to 300,000 megahertzes, is usually used in communication apparatus and radar from 300MHz (megahertz) in early days, begins to be applied to industry and medical science afterwards.In the world for the ease of the standardization of microwave device, and avoid radar system and microwave communication system produced and disturb, the frequency that is given for microwave heating and microwave drying has four sections.
Be respectively: L section, frequency are 890~940MHz, centre wavelength 0.330m;
S section, frequency are 2400~2500MHz, and centre wavelength is 0.122m;
C section, frequency are 5725~5875MHz, and centre wavelength is 0.052m;
K section, frequency are 22000~22250MHz, and centre wavelength is 0.008m.
Only use S section (2450MHz) in the household microwave oven.The microwave of 915MHz (commercialization) is used for equipment such as the large-scale baking, sterilization, drying of industry and commerce department more, also S sections (2450MHz) that adopt in the present armarium more.
The inventor thinks through a large amount of research; The microwave electromagnetic radiation is used for the biological heat engineering in medicine has 13 big characteristic microwaves to be used for the medical science physical therapy or treatment is called heat ray.
(1) microwave runs into metal object and knows from experience and to be reflected as the specularly reflected visible light, so common metal is isolated, transmission microwave thermal ray.
(2) microwave runs into insulant and can pass through as light transmission glass is smooth.Therefore, can make special implement with insulant, and not influence the radiation heating effect of heat ray.
(3) microwave runs into moisture or fatty material, can be absorbed in large quantities, and is converted into heat energy.Owing to contain moisture in the human body various types of electric charges are arranged again, so the overwhelming majority organizes and can conduct electricity.Though the structure of human body is complicated unusually, but analyze also nothing more than being by 12 kinds of basic element (carbon, hydrogen, oxygen, nitrogen, sulfur, phosphorus, chlorine, sodium, potassium, calcium, magnesium, ferrum) and other trace element (cobalts, zinc, manganese, copper etc.) form, the mutual chemical combination of these elements constitutes water, protein, fat, sugar, inorganic salt etc., wherein moisture is present among the various histiocytes in a large number, by the body weight percentage calculation, water accounts for more than 60% at the intravital content of people, many materials always are dissolved or suspended in the water of body fluid in the human body, and many biologicallies all are to carry out in the water of body fluid.Water (H2O) frequent hydrion (H+) and the hydroxide ion (OH-) of dissociating into micro-ly.Glassware for drinking water has very big dielectric constant, and the dielectric constant of pure water in the time of 20 ℃ can promote electrolytical dissociating.
The liquid (or water) that exists in the body is called body fluid, is to have dissolved inorganic matter and organic a kind of liquid.In the body fluid inorganic matter and partial organic substances exist with ionic condition, be called electrolyte; And not dissociated materials such as glucose, carbamide are called non-electrolyte.Because the moisture that contains in the human body has various types of electric charges again, so the overwhelming majority organizes and can conduct electricity.
Water accounts for more than 60% at the intravital content of people.The body foci position contains a large amount of microbial cells and water (body fluid) and fat, is exactly that a kind of liquid with charged ion is arranged in the human body in addition.If the human lesion medium is placed in the electric field of alternation (microwave), medium will be by remagnetization, and Here it is is better than other medium on every side because microbial cell liquid absorbs the ability of microwave.Extra electric field voltage is high more, and degree of polarization is strong more; The extra electric field change in polarity is fast more, and the frequency that promptly adds alternating current is high more, and human lesion position medium molecule alternating polarization is frequent more.Except the phenomenon of alternating polarization repeatedly of molecule, also can produce and quicken to move, cation is shifted to the electric field negative pole, and anion is shifted to the electric field positive pole.Along with the variation of microwave field frequency, the direction that ion moves is also along with variation.Must bring the quick swing of molecule and collision of molecules, friction and produce heat.The intermolecular heat that produces owing to polarization will reveal from macroscopic view.Therefore the cell membrane in microwave electromagnetic field will break rapidly and cause thalline death." microwave thermotherapy " is exactly to utilize this characteristic to come the human lesion position is carried out the heating in deep, and the high velocity impact division of focus cell reaches the order ground of radical curing of disease till death.
Our blood circulation system transports three kinds of passengers; Erythrocyte, leukocyte and platelet.It is to be generated by our medullary cell for a platelet.Platelet and erythrocyte have accounted for 45% of our blood, and remaining is a serum.Isolated serum is xanchromatic liquid, contains 90% water and 10% chemical substance.In the inside of bleeding 5,000,000 erythrocyte are arranged, 7000 leukocytes and 250,000 platelet, there are about 5 liters of blood in our body-internal-circulation, the erythrocyte that is carrying oxygen and some carbon dioxide is suspending in serum and is flowing forward, leukocyte is responsible for and the disease operation, and slight platelet then helps our blood clotting.
(4) " microwave ultrasound " has " sonochemistry " characteristic.April 14 nineteen sixty-eight, Britain's " safe I scholar reports " report; " a new industrial revolution in the offering, it will make the traditional biological technology of plastics, detergent, pharmacy and agriculture chemistry take on an entirely new look, and its impayable advantage is exactly that it is safe and cheap.It does not require the high temperature and high pressure condition in the existing production, and the energy of consumes least only, is called as the new subscience of ' sonochemistry ' ".At present, its high temperature, high pressure can be applied to the treatment field of chemistry, biology and human tumor, such as, be applied to and chemically just can make the carrying out chemical reaction fast that is difficult to carry out chemical reaction.
The new phenomenon that one " sonoluminescence " arranged in " sonochemistry ", can form a little air bubble as body fluid (or blood) the inside at tissue, cell or tumor (or cancerous cell), after the body fluid the inside realizes that " microwave ultrasound " (frequency of ultrasonic claims " microwave ultrasound " when similar to microwave frequency) suspends, can be positioned at it on the wave amplitude of a standing wave.Then, it can carry out violent compression afterwards to add microwave ultrasound, and after the compression, volume also can be compressed into 106Power doubly.Its all expanded in time of the one-period the inside overwhelming majority, have only seldom in a flash in compression, its energy has improved 10 on time and space altogether12Therefore power doubly just can be directly changed into " microwave ultrasound " energy the energy of light.
If we are applied on the biomedicine, can excise certain a part of unwanted thing.Because its high temperature and general high temperature are different.Its high temperature is the high temperature of locality, and temperature is very high in the bubble, and bubble is outer consistent with ambient temperature.So, all be difficult to realize to other any method of its such temperature difference.But, also has only the temperature of room temperature on the limit of its bubble as the inside Da Wandu of its bubble.This is to be difficult to realize, the profoundness of its kill tumor also just here.
(5) microwave can reduce thermograde greatly.In the physics, temperature is meant a certain specified point, in same temperature field, and the measurement point difference, the numerical value that obtains is also different.Only in absolute even temperature field.Thermograde is meant the number of degrees that temperature descends or rises on the unit distance, and it is relevant with the distribution in temperature field.To intravital certain focus individual Temperature Distribution is arranged from body surface.It is far away more promptly to leave radiation therapy head, and temperature is low more.Usable temp gradient delta T represents.Adopt the temperature of " microwave thermotherapy " not high, but,, can make body or intravital certain focus reach required treatment temperature so thermograde Δ T can be very little because of the corresponding growth of its treatment time.
(6) microwave is the ripples shape of diffusion type to the radiation of human body.As long as the temperature that is radiated human body below 43 ℃ certainly to not hurting sb.'s feelings.From figure below as can be seen, microwave is the ripples shape of diffusion type to the radiation of human body.As long as the temperature that is radiated human body below 43 ℃ certainly to not hurting sb.'s feelings.Can also come like this than in, the electromagnetic wave of laser and ionizing ray and so on just as with a pinprick on human body, people can feel bleed, pain, and microwave electromagnetic waves is just as being placed on the human body with palm, people can not feel pain.
Fears are entertained that, and microwave oven can be hurted sb.'s feelings.Temperature in the microwave oven is up to more than 400 ℃, if microwave oven goes out microwave electromagnetic waves from the ovfl of door, so, the leakage temperature of moment will be up to more than 400 ℃, the tissue of the human body of will burning certainly.Here be not that microwave electromagnetic waves has injured human body, but the high temperature more than 400 ℃ that the microwave oven internal leakage goes out can be burnt or smelt is hurted sb.'s feelings body.Concerning human body, will burn more than 45 ℃ or the smelt wound.
Microwave is the high electromagnetic wave of a kind of non-electricity.Microwave is because microwave electromagnetic field makes the intravital molecule high speed rotating of human body when human body is heated, and friction produces the result of hyperpyrexia mutually.It is the process that electromagnetic energy converts heat energy to.The end powered-down in case heat, just microwave generator closes, at this moment microwave electromagnetic field also just disappears simultaneously, inside of human body just can't produce heat energy by electromagnetic energy again, so microwave heating also just can not have microwave to be retained in people's the body when finishing, therefore adopt microwave that human body is heated as long as be impossible produce harm below 43 ℃ to human body.Be higher than 45 ℃ thermostimulation, make the mechanical stimulus that " nocuity distortion " takes place skin wait strong stimulation or noxious stimulation, the nociceptor that acts on respectively temperature and mechanical sensitivity all can cause pain, simultaneously the damage of accompanied by tissue.
(7) kelvin effect of microwave.Alternating current can not uniform distribution, but focuses on the surface of body.Along with the rising of frequency, this influence is all the more obvious, and promptly the conductivity of body and permeability strengthen thereupon, is limited to up to electric current till the thin layer (skin) of body surface, and this phenomenon is called kelvin effect.It can improve the virtual impedance of the body of conduction microwave energy effectively, and kelvin effect can significantly strengthen, so that plays the effect of shielding treatment.
(8) the waveguide type microwave can carry out external hyperbaric oxygenation treatment simultaneously, guarantees the safety in the long-time whole-body hyperthermia treatment.
When microwave thermal ray during for a long time to human body radiation, the temperature of body can rise, the juice pore of whole body all is opened, blood vessel can be expanded, blood can heat up thinning and accelerate flow velocity, and at this moment serious scarce nutrition and anaerobic condition can appear in body, can cause immunity to descend greatly, simultaneously symptoms such as stupor, shock will occur, even can cause death.This is that microwave current can't be used for the main bottleneck of long period to whole-body hyperthermia.
A scientist of " life of no blood " 1956 Holland be Bao Ruina he done the test of a hyperbaric oxygentherapy.He has nearly all been taken out the blood in this tremulous pulse with a piglets, gives from vein and replenishes saline, and that flows in the blood vessel of this piglets like this has not just had erythrocyte, is saline fully.So certainly, this piglets will be dead under the condition of nature.
This piglets is placed on the inside, an oxygen cabin but Bao Rui puts on airs, and has filled 3 atmospheric oxygen then in the oxygen cabin, and in the middle of the environment of these 3 atmospheric pressure oxygen, this piglets can also live 15 minutes normally.The Bao Rui blood of putting on airs has been failed to piglets again and has been gone back after 15 minutes, then piglets is released in the test chamber of getting back to him in the oxygen cabin, and this piglets is living in the same old way still, and the electrocardiogram of doing is also still normal.In other words, one bleeds does not have yet, this piglets can live in the same old way in 3 atmospheric oxygen cabins.At this moment not to transport oxygen by erythrocyte, but by dissolved oxygen.At this moment sure says, the dissolved oxygen in the piglets blood vessel in the mobile saline is than much more under natural environmental condition.So, just write one piece and cried the article of " life of no blood " according to this test Bao Ruina in nineteen sixty, be published in the medical circle that has caused a sensation All Around The World on the surgical magazine of the U.S. at last.
It mainly is that blood vessel to human body heats that microwave is used for treatment to human body, when fervescence, the juice pore of whole body all is opened, when microwave thermal ray intravasation, (frequency of microwave is the vibration of per second 24.5 hundred million times because " microwave ultrasound ", can be referred to as meaning " microwave ultrasound ") effect have very strong extrusion capability, can clamp-on the hyperbaric oxygen in the oxygen supplement treatment cover " sonochemical effect " takes place in the blood vessel; That blood vessel can be expanded, blood can heat up is thinning, thrombosis can shake broken fusing, and can set up new microcirculation or open the part blood capillary, because the entering of oxygen, and the fresh oxygen of having given blood transport, but the Therapeutic Method of appellation " microwave+dioxygen+immunity ".
When carrying out " microwave ultrasound " hyperbaric oxygen cover when treatment, fervescence, the juice pore of whole body all is opened, and the utilization rate of the oxygen supply of tissue and oxygen is increased and activate blood capillary, and the immunity of enhancing body.Can be pressurized in body surface or the body external oxygen is the most effective, will impel the generation of chemical reaction, and can not occur under this Therapeutic Method that is reflected at other.The microwave thermal x radiation x of whole body long period with cooperate the oxygen supplement cover, be in the treatment, late malignant tumour (cancer) is unique, also be the most effective Therapeutic Method.
(9) the waveguide type microwave can carry out intravital oxygen therapy liquid simultaneously, guarantees the safety in the long-time whole-body hyperthermia treatment.
When microwave thermal ray during for a long time to human body radiation, the temperature of body can rise, the juice pore of whole body all is opened, blood vessel can be expanded, when fervescence, the juice pore of whole body all is opened, the perspire that this moment can be a large amount of, cause symptoms such as dehydration or collapse, stupor, shock and immunity to descend greatly easily, even can cause death.This is that microwave current can't be used for the main bottleneck of long period to whole-body hyperthermia.
The waveguide type microwave can carry out intravital oxygen therapy liquid simultaneously, in can carrying out when micro-wave therapeutic, the doctor trained in Western medicine vein point oxygen of annotating hyperbaric oxygen liquid, the medicine oxygen that mixes transfusion, blood mixes the oxygen mixing treatment of blood transfusion, chemotherapeutics and drink the blended health-care physical therapy of oxygen that drinks water etc.The oxygen that can carry out high concentration to oxygen therapy liquid mixes, and medication few (particularly important in the chemotherapy) cure rate height, therapeutic effect are splendid, and treatment will be shortened the course of treatment greatly.In general, erythrocytic diameter is less than 6 μ m, and the diameter of blood capillary is 5 μ m, and erythrocyte has only distortion to become strip, and its diameter just can carry out in the blood capillary when 3 μ m.The microwave thermal ray can make red blood cell deformation.So, require oxygen and the mixed granularity of transfusion could the most effectively enter the purpose that reaches treatment in blood, cell and the blood capillary at nanoscale.
When micro-wave therapeutic, cooperate oxygen therapy liquid just can in various, the tumor patient in late period carries out the complete more safe treatment of the heat ray of long period, just can not cause symptom and immunity degradation or death such as dehydration or collapse, stupor, shock.On the contrary, can improve immunity and kill tumor cell.But the Therapeutic Method of appellation " microwave+polyoxy+immunity ".
The inventor is through quantity research and clinical treatment and observation are thought greatly; The microwave thermal ray can reopen the blood capillary of part and activate erythrocyte in the blood when the treatment of long period, at this moment, and the most effective delivery of supplemental oxygen and nutritional solution immediately; The one, can enhancing immunity, the 2nd, can heat to the cancerous cell of whole body, the 3rd, can the most effective cancerous cell that kills whole body, be the most effective means and the Therapeutic Method of a kind of centering, late tumor patient treatment.
(10) inventor has confirmed also that through a large amount of research microorganism and some sick cells all have magnetotaxis.This characteristic is very crucial and important with the killing microwave cancerous cell time.
This Therapeutic Method that rediscovers is used for the treatment of cerebroma, and cerebroma is fatal often.If patient's head is in the mutual magnetic field of microwave, because the distinctive magnetotaxis of cancerous cell, all can gather the place, magnetic field of microwave radiation, thereby cancerous cell will be heated between 43 ℃-46 ℃ and killed by microwave high-temperature.
(11) iron atom and the magnesium atom in the haemoglobin molecule of redness is metallics in the blood, in the time of in microwave electromagnetic field is radiated intravital blood, because the metallic iron atom in the blood and the existence of magnesium atom will produce eddy current,, the temperature of blood kills cancerous cell thereby being raise fast.
(12) when microwave heating makes the temperature rise of blood vessel expander, leukocyte can be secreted toxin and antibacterial and cancerous cell and struggles, and kill cancer cell.
(13) when microwave was used for cervical vertebra blood vessel to cerebrovascular disease and carries out thrombus cleaning, it can not form fritter, and can be crushed into minimum powder by microwave, and can be taken away by blood smoothly or circulate normally.
Blood capillary expands with heat and contract with cold and regulates the effect of body temperature in the skin
Skin is the contact surface of health and external environment, also is the organ of human body maximum.Its weight is 15% of human body weight, and 12 meters long blood vessels are arranged in every square metre the skin.Skin can reflect the health status of the various organs of our body interiors, for the various stimulations in the external world, and for example pain, temperature, pressure etc., the function of skin performance protection, regulate body temperature and consciousness.
Skin surface is to play cross-distribution by many tiny concaves and Gansu Province to form, and the surface of skin comprises sulci of skin, ball and three parts of fine hair.The cross section structure of skin comprises epidermis, corium and three major parts of subcutaneous tissue.
Epidermis is the multi-ply construction that does not contain blood vessel, is followed successively by horny layer, granular layer, cortex and basal layer from outside to inside.Because the continuous regenerated characteristic of epidermis makes it become the youngest organ in all organs of human body.
Corium be next to epidermis below, much thicker than epidermis, have vascularity wherein can support and the nutrition epidermis.
The following of corium promptly is subcutaneous tissue, and subcutaneous tissue is made of subcutaneous fat.Subcutaneous tissue can prevent dispersing of body temperature, and relaxes the bump stimulation that comes from the outside with the effect of liner, can store with the form of fat for energy unnecessary in the body.
Skin comes the influence of abirritate to health by feat of the variation of various characteristics structure and cell.Skin is when being subjected to environmental stimuli, and brain can be offered an explanation out stamp, pressure, consciousness such as hot and cold, painful, and issues order to parts of body, to deal with external situation.
In the face of the ambient temperature that constantly changes, keep stationary temperature in the body, skin plays a part regulate body temperature.Skin meeting sebum secreted to keep the moist of skin surface, prevents the intrusion of moisture by evaporation of angle fat layer and external substance.
The secretion of sweat is the discharge evaporation by means of moisture, to reach the purpose of distributing the body heat regulate body temperature.
The function of the protection of skin, breathing, regulate body temperature and consciousness makes it so important in our health.Yet skin is the first road system of defense of human body, is human body and extraneous contact surface, so it also is faced with many problems.
Blood capillary has the function that absorbs nutrition and drain refuse.Blood circulation is except absorbing nutrition and draining the refuse, and also the companion is drilling a key player, is exactly regulate body temperature.When the temperature of human body raise, the tube wall of blood capillary will be expanded, and the blood flow in the tube wall will be accelerated, and the temperature in the blood will be gone out to evaporation by quick mobile blood, and at this moment, the body temperature of human body will reduce.
If when the hypothermia of human body, as cold weather or and during hypothermia through refreshing anxiety, the contraction that the tube wall of blood capillary will be tightly, the flowing velocity of blood slows down, the temperature of blood of human body the inside just can obtain to keep, and it is too too low that our body temperature just can not descend.When the temperature in the external world was very low, blood capillary was in order to keep body temperature, and the tube wall of blood capillary will be contracted in simultaneously closely.When temperature raises, the work of the tube wall of blood capillary with regard to needing expansion to dispel the heat.When blood capillary had no idea to carry out any contraction again, the one by one red blood streak will be seen in the surface of skin, just the have no idea blood capillary that moves again of these bloods streak, just telangiectatic phenomenon.
The skin of many sensitivities can see clearly has the red one by one blood streak on the face, is prone to most below nose or on cheek, and big more people of age is just obvious more.
Skin also has respiratory function.Skin can absorb oxygen, and discharges carbon dioxide.But, to compare with respiratory system, the Repiration of skin only accounts for below 1% of human body respiration effect.
In hot summer, air themperature height, high humidity, Skin Cell substitute to be accelerated, vigorous, the patulous follicular orifice of glandular secretion, and the sensitivity of skin strengthens, and at this moment sebaceous gland acidity lowers, skin trend alkalescence, antibacterial is invaded easily in resistance against diseases decline.
The sun beats down for torridity summer, from ultraviolet too much in the sunlight skin had very big injury.Though ultraviolet can kill the antibacterial of skin surface, strong excessively ultraviolet can destroy the cell of skin, causes the vasodilation hyperemia of skin superficial face, even the pustule edema, causes the illness of skins such as skin carcinoma.
Ultraviolet radiation in summer between often makes the anti-pre-increased functionality of skin instinct, and a large amount of pigment granules concentrate on the basal cell layer of epidermis, and with the opposing ultraviolet irradiation, this causes skin can become more black, promptly so-called " tanned ".Simultaneously, also cause chromogenesis speckle, freckle and chloasma to occur easily, it is excellent in important that the utilization of correct sun-proof method just seems.
Sunlight can make people's transition aging, wrinkle, blackening occur, so-called " smooth bark skin, photoaging " symptom occurs.So everybody is selecting with sunscreen cream now.
The aerobatic exercise meeting brings not to the utmost health-benefiting to people
According to survey, when aerobatic exercise, the oxygen that human body sucks is 8 times under the rest state, adheres to that for a long time aerobatic exercise can increase the quantity of hemoglobin in the body, improves Abwehrkraft des Koepers, strengthens corticocerebral work efficiency and cardiac function.Simultaneously, can also increase the physical ability water consumption, prevent that arteriosclerosis from reducing the sickness rate of cardiovascular disease.That is to say, adhere to that aerobatic exercise will oneself bring not to the utmost health-benefiting for us.
We advocate aerobatic exercise, mainly from two aspects; On the one hand, can reduce intravital blood fat by motion, the fuel that aerobatic exercise will consume is fat, and fat constantly decomposes at the volley supplies the energy of musculation.At this moment, blood fat will decrease in the not daily exercise, and the reduction of blood fat is very useful to cardiovascular health.Aerobatic exercise not only improves the function level of blood vessel, and can improve the function of heart.Palmic rate slowed down when this mainly showed peace and quiet, and heart beating is whenever fought and exported the blood volume increase.
Common people 70~80 times/minute, often participating in aerobatic exercise, to listen the people be 50~60 times/minute, the elite is only more than 40 time/minute.Here it is because the output that the athlete whenever fights is big, thereby, though palmic rate reduces the needs that still can satisfy general metabolism.
For example, 4.5 liters of/minute blood of heart just can satisfy the general metabolism needs under rest state, and so, common people's stroke volume is 60 milliliters,
Then heart is 75 times/minute.The people's stroke volume that often takes exercises is 90 liters.Heart only need be beaten and can be satisfied the demand for 50 times.The heart beating frequently width of cloth is slowed down and heart more had a rest be not easy fatigue.
Aerobatic exercise will consume oxygen in motor process, want lot of energy simultaneously, and these energy mainly come from fatty tissue because fatty tissue it more heat can be provided, fatty tissue also is our intravital energy reserve storehouse in addition.
A large amount of studies show that, aerobatic exercise has the effect of slight appetite-suppressing, we depend on the motion physical exertion of certain level to the sensitivity of appetite regulation, if be in a kind of life style of static state for a long time, the amount of your consumption of the big what of the amount that you eat is if you often participate in sports activites, although you have felt many a little a bit, in fact, your amount of eating is still smaller than the amount that you consume.
The much health educations of the many logical sequences of Canada man comes rope.Find with more than 300 relevant tests by long-term observation, when people feel brain fag, can make the functional rehabilitation to 58% of brain to outdoor stroll 800 people.Do not take medicine and do not take exercises to change into, the function of brain only recovers 40~50%.We can say that jogging has special effect to refreshment.Aerobatic exercise simultaneously also possesses the effect of recovering physical ability.Adopt this positive reset mode, when very tired, join in the infusive health population and carry out body building.As, in the gymnasium, follow graceful music to do a kind of rhythmical fitness exercise, adjust the most obvious to the emotion and the muscle power in future.
The aerobatic exercise meeting brings not to the utmost health-benefiting to people.But reach the effect of body-building, also must get hold of degrees of motion.That is to say that it is an amount of that motion is wanted.Everyone is because of the difference of body constitution, and it requires different.
The physiology of respiration of hyperbaric oxygen medical science is learned the basis
Human body is constantly inhaled people's oxygen, gives off carbon dioxide, and carries out metabolism.Gas exchange process between external environment and the blood is called external respiration; Blood and histiocytic gas exchange process are called internal respiration; The biological oxidation process of cell is called Tissue respiration.
One, human body exchange gas
The human body gas exchange carries out at alveolar.The surface area of alveolar is very big, the outside of alveolar is the pulmonary capillary net that enriches, gas in the alveolar and the blood in the blood capillary only be separated by alveolar wall and blood capillary inner membrance, the gross thickness of this double-layer films is 1~2 micron, therefore the as easy as rolling off a log mutual disperse of gas in IA gas and the blood.
The disperse of gas molecule mainly is owing to molecular motion causes.Gas depends on the pressure difference of this gas in spatial disperse direction, speed and distance, gas originally always from the position, higher-pressure region to the disperse of low-pressure area position, concerning the total pressure of mist, so, concerning this partial pressure of various gas, also be like this.Pressure difference is big more, and the speed of gas dispersion is fast more, and distance is far away more.
Experiment is measured, and when health adult usually depressed suck at room temperature, partial pressure of oxygen was 13.7kPa (103mmHg) in the alveolar; Partial pressure of carbon dioxide is 5.3kPa (40mmHg); And the partial pressure of oxygen of alveolar blood capillary venous blood is 5.3kPa (40mmHg), partial pressure of carbon dioxide is 6.3kPa (47mmHg), therefore the oxygen in the alveolar is with regard to the disperse human blood, and the carbon dioxide in the blood is then discharged from alveolar, finishes the gas exchange process of alveolar and blood.Should be noted that the gas in the alveolar will be dissolved in earlier in the liquid of alveolar membranous wall tissue just can enter blood, and carbon dioxide dissolved needs also by becoming gaseous state and people's alveolar behind the alveolar membranous wall in the blood.Carbon dioxide passes through the speed of alveolar less than the speed of oxygen by alveolar, and nitrogen is then slower by alveolar, so the carbon dioxide in the blood more easily excretes difficult retention in vivo.
It is significant on physiology of respiration is learned to the diffusing capacity of oxygen to measure alveolar.When the difference of the dividing potential drop of same gas in certain gas and the blood in the alveolar was 0.13kPa (1mmHg), this gas of per minute was called the dispersion coefficient or the disperse constant of lung by the total amount of alveolar membrane.
The dispersion coefficient of healthy people oxygen when peace and quiet is about 15~20ml, and per minute is breathed 16~20 times, absorbs the about 300ml of oxygen, discharges the about 250ml of carbon dioxide.But when physical work or strenuous exercise.The maximum dispersion coefficient of oxygen can be up to 60ml, and gas exchange can increase more than 10 times.This mainly is that pulmonary capillary is opened due to number increase and the telangiectasis.In addition, blood is to produce about 3 times of complete oxygenate required time by resting on time in the pulmonary capillary, makes blood be able to complete oxygenate, to guarantee the increase of body to oxygen demand.Old people's lung dispersion coefficient reduces.May be because the cause that pulmonary capillary reduces.
Alveolar membrane thicken or alveolar in have when oozing out (as pulmonary edema) its permeability descend; Airway obstruction, pneumonia or lung atrophy can make the oxygen that enters in the alveolar reduce; During shock state, pulmonary blood flow volume reduces, and pulmonary capillary contraction etc. all causes alveolar and blood gas exchange obstacle, thereby the body anoxia.In the body circulation, the gas exchange between blood and the tissue is also followed the principle of dividing potential drop.Organize continuous oxygen consumed and generate carbon dioxide, therefore its partial pressure of oxygen is low, and the partial pressure of carbon dioxide height, according to indirect determination, PtO2 is 2.7~6kPa (20~45mmHg), than the arterial partial pressure of carbon dioxide height, thus carbon dioxide by organizing disperse to go into blood, thereby finish gas exchange process between blood and the tissue.
Two, gas is in the intravital transportation of machine
(1) transportation of oxygen
When oxygen diffuse was gone in the blood, the transportation of oxygen had two approach: the one, combine with hemoglobin, and become HbO2 Oxyhemoglobin (HbO2), make blood be cerise.Known every gram hemoglobin can be in conjunction with the oxygen of 1.36ml, and the blood of every 100ml contains the 14g hemoglobin approximately, so oxygen content is about about 1.36 * 14=19ml (19Vol%) in the blood of common every 100ml.Partial pressure of oxygen (the PaO of normal arterial blood2) being about 13KPa (100mmHg), this moment, the oxygen saturation of hemoglobin reached 97%, if oxygen transports with this form under the normal pressure.The 2nd, oxygen directly is dissolved in the blood plasma with physical state, as mentioned above, physical dissolution oxygen amount only is 0.3ml in the blood of every 100ml, be quite few, but histiocyte is at first to utilize this a part of oxygen, just hemoglobin is carried out the transition to dissolved state in conjunction with oxygen then, permeates in the interstitial fluid again, for the cell utilization, so the physics dissolved oxygen is considerable.
The disassociation of HbO2 Oxyhemoglobin, depend on following Several Factors:
1. partial pressure of oxygen: the oxygen discrete curve of blood is a serpentine, partial pressure of oxygen roughly 5.3~6.7kPa (40~50mmHg) when following, the gradient steepest of curve, more than then gradually flat; At partial pressure of oxygen is that (100~110mmHg) time, HbO2 Oxyhemoglobin is saturated substantially for 13.33~14.7kPa.Partial pressure of oxygen just often is that HbO2 Oxyhemoglobin can dissociate out with it rapidly with this understanding below 5.3~6.7kPa in the body tissue, so have very big physiological significance.
2. hydrion (H+) concentration: H in the blood+Concentration is to oxygen dissociation curve generation tremendous influence, H+Concentration is high more, and then hemoglobin is more little in conjunction with the ability of oxygen, institute's Weihe Bohr effect that Here it is.
3. partial pressure of carbon dioxide: under same partial pressure of oxygen, partial pressure of carbon dioxide is high more, and then the quick saturation of hemoglobin is low more, the low and partial pressure of carbon dioxide height of partial pressure of oxygen in the tissue, oxygen just dissociates from HbO2 Oxyhemoglobin and comes out to supply tissue, and carbon dioxide enters blood simultaneously.
4. body temperature: fervescence can make the oxygen supply of tissue and the utilization rate of oxygen increase.
5. 2,3-diphosphoglyceric acid (2,3-DPG): it is believed that normal DPG concentration takes over the dissociation curve of HbO2 Oxyhemoglobin in the blood.During anoxia, DPG increases, and curve is further moved right, and this makes oxygen evolution in tissue, makes the rising 1.3kPa of PtO2 (10mmHg).
6. motion: muscle produces acidic materials such as a large amount of carbon dioxide and lactic acid during motion, and the temperature of muscle raises 3~4 ℃ simultaneously, therefore can quicken oxygen and disengage from HbO2 Oxyhemoglobin, enters in the muscular tissue, makes its partial pressure of oxygen be higher than 5.3kPa (40mmHg).
In vivo under the situation of ambient stable, pulmonary absorbs and is transported to the oxygen amount of tissue by each link, must equate with organizing oxygen consumption.Oxygen can be represented with " circulating resistance " this saying to the transportation of tissue from air.Here, drag overall equals closing of a series of minutes resistances.In this transportation, because this resistance reduces partial pressure of oxygen gradually, at mitochondrion oxygen consumption place even can be reduced to below the 0.13kPa (1mmHg).
(2) transportation of carbon dioxide
Carbon dioxide content is about 60ml in every 100ml blood.The transportation of carbon dioxide is similar substantially to the transportation of oxygen, and a part (6%) directly is dissolved in the blood.The solubility factor of carbon dioxide in blood plasma is 0.541, and its dividing potential drop in venous blood is 6.1kPa (46mmHg), and therefore every 100ml venous blood carbon dioxide dissolved amount is (0.541 ÷ 760) * 46 * 100=3.2ml.Part carbon dioxide then directly combines with hemoglobin, becomes carbaminohemoglobin (HbCO2).Should be noted that the bonded position of oxygen and carbon dioxide and hemoglobin is inequality, oxygen combines with the heme moiety of hemoglobin, and carbon dioxide combines with the protein amino part of hemoglobin.When oxygen and hemoglobin were combined into HbO2 Oxyhemoglobin, carbon dioxide is just difficult to be combined with hemoglobin.
Otherwise carbon dioxide easily combines with reduced hemoglobin, is transported to pulmonary.In pulmonary capillary, after hemoglobin and oxygen were combined into HbO2 Oxyhemoglobin, a part of carbon dioxide will disengage automatically, discharged outside the lung, and the carbon dioxide that this means of transportation is discharged accounts for 20% of whole carbon dioxide outputs.
The topmost means of transportation of carbon dioxide is: the carbon dioxide that produces in the metabolism, infiltrate in the erythrocyte, and under the effect of erythrocyte carbonic anhydrase, with the aquation carbonate synthesis, and the carbonic acid molecule further dissociates into H+With HCO-3When endoerythrocytic increasing, HCO-3Just with blood plasma in chloride ion (Cl-) exchange mutually, enter in the blood plasma, be combined into bicarbonate (BHCO with alkali3), and the important buffering of forming in the buffer system of blood with carbonic acid is right, regulates the acid-base balance of blood.
Three, biological oxidation
Oxygen behind tissue, participates in the biological oxidation process of cell with enzyme system by blood transport, generates carbon dioxide and water at last, and emits energy.
Biological oxidation claims cellular oxidation or Cellular respiration again, and it mainly carries out on the mitochondrial ridge of cell.The paired hydrogen atom (2H) that mitochondrion is taken off metabolite progressively transmits by the chain reaction of being made up of plurality of enzymes and coenzyme dimension, and final and oxygen is combined into water.In this process, the picked-up oxygen of cell is relevant with Cellular respiration, so the chain reaction of this oxyhydroxide is called respiratory chain.Energy matter is under-supply, respiratory chain generation obstacle, and anoxia all can influence biological oxidation process.
The physical basis of hyperbaric oxygen medical science
Normal pressure (0.1MPa) down during breathe air, intra-alveolar oxygen concentration 14.3%, alveolar pO2 is PO2=(atmospheric pressure-water vapor pressure) * 14.3%=(760-47) * 14.3%=103mmHg=13.7KPa.
If suck pure oxygen under normal pressure, then the partial pressure of oxygen alveolar pO2 is PO in the alveolar2=760-(47+40)=673mmHg=89.5KPa.Increase when sucking air and almost reach 7 times.
If under 0.2Mpa, suck pure oxygen, alveolar pO2 PO then2=760 * 2-(47+40)=1433mmHg=190.6Kpa increases about 14 times during at this moment than the normal pressure suck.And under 0.3MPa, suck pure oxygen, and alveolar partial pressure reaches 291.7KPa (2193mmHg), during for the normal pressure suck 21 times, and the rest may be inferred by analogy.
When gas and liquid were in contact with one another, gas can be dissolved in the liquid.At a certain temperature, its dissolubility pressure is directly proportional, until in the liquid during the mutual balance of the gas pressure on gas pressure and the liquid level, dissolves and just stops.
As when calculating the normal pressure breathe air, physics dissolved oxygen amount in every 100ml blood, the solubility factor that is dissolved in the blood from the oxygen as can be known of tabling look-up is 0.023, under the normal pressure during breathe air, alveolar pO2 is 13.7KPa (103mmHg), if press 100mmHg calculating, then in the 100ml blood oxygen amount of physical dissolution should for; 0.3 (Vol%).
During temperature constant, the volume and the pressure of gas are inversely proportional to.
When blood vessel in the body or when organizing the gassing thromboembolism, bubble is general rounded or oval.When using hyperbaric oxygentherapy, according to boyle-boyle's law, when pressure rises to 0.2Mpa, bubble be contracted to original volume half when rising to 0.3Mpa, bubble is contracted to 1/3.Along with pressure increases, bubble dwindles gradually, is recovered normal blood circulation gradually by the blood vessel of gas bubble blockage, and symptom can disappear, so hyperbaric oxygen is usually used in treating air embolism and decompression sickness.
Learn from the Zong Yuan of naval that recently this institute is achieving notable results aspect the hyperbaric cabin treatment cranium disease of brain.
The method of hyperbaric cabin treatment cranium disease of brain is that the patient who suffers from the cranium disease of brain is sent in the special hyperbaric cabin, air pressure in the cabin is elevated to one more than the normal atmosphere (doctor of Navy General Hospital uses 3 atmospheric pressure to treat), impel the patients'blood dissolved oxygen amount to improve, patient is under up-to-date hyperbaric oxygen chamber therapy, the dissolved oxygen amount of blood can increase by 20~30 times, the blood dissolved oxygen plays a role with contacting of hemoglobin, finally makes because the cranial nerves of traffic accident damage has obtained recovery.Through Tangxian County, Hebei of this hospitalize peasant Song Hongshan, after the cranium brain function recovers, now can recently, Bethune's stone image that he carves personally be given to Navy General Hospital from the former occupation of Shinkansen oneself.
AUS to the injury of microwave the results showed into
Research for microwave weapon is of long duration, before 30 years, classify killing and wounding of microwave as the primary study project in the new weapons scientific research task of former Soviet Union Ministry of National Defence with failure mechanism, the generation of the emission source of development ultra high power, strong microwave and propagation and by force aspects such as microwave and matter interaction all obtained certain achievement, and recognize that microwave is to health effects:
The test of AUS shows:
When microwave energy density reaches 0.5w/cm2The time, heat effect can cause the human body skin minor burn;
Reach 20w/cm2The time, eyes, skin and interior tissue meeting serious burn,irradiation time 2 seconds can cause three degree skin burns; Reach 80w/cm2The time, the people is got killed.
The microwave heat therapeutic temperature is harmless to eyes crystalline lens and testis below 43 ℃
Microwave frequency is 2450MHz, and it can not penetrate injury of human internal and tissue, just skin and body surface organization is influenced to some extent, and is generally not unhealthful.The scientist who has thinks, because the eyes crystalline lens has blood vessel heat radiation and testis weak heat-dissipating, therefore under long-time powerful microwave radiation, human body is the easiest, and what come to harm is eyes crystalline lens and testis.
But microwave therapy apparatus in fact of the present invention is when treatment, select for use below 43 ℃, the cutaneous sensation of human body is less than feeling the prick, thus may not injure to some extent eyes crystalline lens and testis, only to head treatment the time to eyes in addition shelter-clad get final product.
Microwave is to the influence of biology
From the viewpoint of electrical engineering, organism also is one of electric dielectric material, but the electrical property in the whole organism and inhomogeneous.Therefore, microwave to the influence of biology one by one organ, partly scrutinize one by one.Microwave to biology influence can be divided into four classes:
(1) frequency is lower than under the situation of 150MHz, and electromagnetic wave passes through glass by organism just as light.Therefore, the hazardness of this class microwave is very little concerning organism.
(2) under the situation of 1.2kMHz, the organism middle body absorbs microwave to frequency, and is the most remarkable to the harm of internal organs at 150MHz.
(3) frequency is when 1 arrives in the 3.3kMHz scope, and surface and deep all absorb microwave.What microwave oven used is exactly this frequency range.But it should be noted that when frequency is about 3kMHz the easiest injury that is subjected to microwave of retina.
(4) in the frequency range more than 3kMHz, organism surface is several exhales whole absorption microwaves.Injury maximum to skin and eye.
Microwave depends on the dielectric constant and the resistivity of frequency, power density, row ripple or pulse, organism, the factors such as restore funcitons of heat conductivity, ambient temperature, humidity and organism to the influence of biology.Therefore, microwave can not be illustrated simply to the influence of human body.About microwave the report major part of organism infringement is belonged to infringement to eyes.When strong microwave penetration eyes, the albumen in the retina becomes opaque material.Can be defined as 10010mw/cm before the standard mesh of protection retina safety2
The margin of safety of protection testis is 10mw/cm under the situation of 300MHz2But the reliable data of relevant these situations is few, and needs the method for a kind of high-acruracy survey microwave radiation of research.
Extremely low frequency electromagnetic fields is harmful
Extremely low frequency electromagnetic fields receives much concern as one " focus " of bioelectromagnetics research in recent years, and wherein majority is the research to 50Hz or 60Hz electromagnetic field.Extremely low frequency electromagnetic fields can make blood, lymph fluid and cellular plasm change, cause that intracellular DNA (deoxyribonucleic acid) (DNA) is impaired, chromosome damage and gene undergo mutation and teratogenesis shape, and then bring out leukemia of future generation, embryo chromosome change, and cause baby's deformity or spontaneous abortion.
Electromagnetic radiation is with distance, the rapidly decay by index law (be electromagnetic radiation and radiation source square be inversely proportional to) at spatial transmission, so when making electrical appliance, draws back certain distance, can play effective protective action.
Can not decrease brain with mobile phone
For a long time, people can damage with regard to using mobile phone that opinions vary to human body (particularly human brain), make everybody puzzle one's brains with the machine person, on tenterhooks with getting, various prevention products are also used and are given birth to, what radiation-proof antenna, radiation shield etc. allow astute businessman earn one in a down-to-earth manner greatly.Recently, claim that according to the expert of World Health Organization (WHO) research data up to now shows, uses cell phone still quite safe, although have scientific research to show that cellular radiation causes heating up near once Celsius in the human body brain, be not sufficient to brain cell is caused the damage evil.
Even many people worry itself not use mobile phone, be in the radiation field can influence healthy for a long time, but doctor Luo Pazuoli of World Health Organization's specific responsibility electromagnetic field scientific research plan represents that this worry is unnecessary, because can not damage brain cell near intensification once Celsius.But he adds, and a lot of key issues are still waiting research, and present stage can't be made concrete conclusion.The project of beginning in 1996---World Health Organization began from 1996 to unite the separate science tissue that surpasses 40 countries, cooperated and carried out the broad scale research plan in 10 years by a definite date.The evidence of mobile phone potential danger is still actively inquired into and is collected in plan at present, and whether whether the non-thermal effect of seeking cellular radiation causes bad biotic influence, comprise relevant with diseases such as cerebroma, epilepsy, Parkinson's disease, hypomnesis, insomnias.
Doctor Luo Pazuoli says, Information of Science and Technology development nowadays is very fast, but associated research chases after far away and is unable to catch up with, therefore, scientist must accelerate the research progress, otherwise delays everyone when bringing into use mobile phone, has just had no way of the difference of comparison user and non-user.
Biliographic data:
[1] select from: 7 broadcasts of " sonochemistry " central authorities are by Wei Rong rank of nobility academician, acoustic investigation institute of Chen Weizhong professor (doctoral advisor) Nanjing University
[2] select from: " modern communications " once lied prostrate the 12nd page of ripple 1993 the 2nd phase
[3] select from: Huang Ruixiang etc. write the1st edition page 3 in " microwave oven uses maintenance 300 to ask " November in 1997
[4] select from: " day present technique and industrial monthly magazine " 1975 8volume 2 phases, 63 pages of reports
[5] select from: the 19th page of " family doctor " 2000 10 phase
[6] select from: normal China's phase the 22nd 16 days the 7th March in 2000 of " Xinjiang Urban Newspaper " reporter
[7] select from the 177th page of respectful work " microwave quantum physics " Science Press that appoints November in 1980
[8] Wu Zhongqi chief editor " the clinical handbook of medical hyperbaric oxygen Hunan science tech publishing house October in 1997 the 1st edition the 1st time
[9] the 14th printing of Wang Fengwen chief editor " fluid therapy " People's Health Publisher third edition in October calendar year 2001
[10] select from Feng's favour sweet smell (assistant researcher of CAS Electrical Engineering Research Institute.In " world's medical apparatus and instruments " the 1st the 2nd phase of volume
Page 3 is entitled as the article of " temperature problem in the prostate radio-frequency (RF) heat therapy equipment ")
[11] select from " world's medical apparatus and instruments " the 5th volume the 9th phase 77-79 page or leaf in JIUYUE, 1999
MTS-915A type multifunction microwave therapy apparatus Cohan U.S. group
[12] select from: " modern communications " once lied prostrate the 12nd page of ripple 1993 the 2nd phase
[13] select from: " day present technique and industrial monthly magazine " 1975 8volume 2 phases, 63 pages of reports
[14] select from 1 page of " Soviet Union technology speed newspaper " 254 phase in 1974
[15] select from " world technology is translated newspaper " 1989.8.2
[16] select from according to the Soviet Union and select and edit " science and life " 1984.4 phases
[17] select from ' The Times ' Britain JIUYUE in 1976 report on the 4th
[18] select from the 10th page of " world's medical apparatus and instruments " the 5th the 9th phase of volume
[19] select from 21:30 report in " Chinese education radio station " on January 5th, 1999
[20] Hu Yongcheng, Wang Jifang, Lu Shibi, tumor by local thermotherapy and immunity.The foreign medical oncology fascicle, 1994,21:216-219.
[21] Hu Yongcheng, Lu Shibi, Wang Jifang.The application of microwave heat therapeutic in the operation of bone tumor guarantor limb.Chinese Medical Journal, 1998,78:443.
[22] Hu Yongcheng, Wang Jifang, Lu Shibi, etc.The microwave in-situ thermotherapy is protected the variation of limb operation back body's immunity,
Chinese journal of orthopedics, 1997,17:412-415.
[23] Hu Yongcheng, Wang Jifang, Lu Shibi.Natural killer cell activity changes the experimentation observation that reaches the lung transfer impact after the tumor by local thermotherapy.
Chinese Medical Journal, 1996,76:582-584.
Summary of the invention
Can know various malignant tumor (cancer) disease and pain from above-mentioned data; According to national cancer pain on-site investigation, 62% cancer patient has pain in various degree, is increased to 70~80% to late period.The World Health Organization's statistics, the whole world has at least 5,000,000 people to be subjected to the cancer pain torment every day at present, and wherein there are 1,000,000 people in China, and many patients can't bear painful and commit suiside.A doctor who is engaged in clinical tumor got intestinal cancer old age, after transfer to bone, lung again, pain makes one to commit suicide in the several years to he who takes things philosophically.He says: " wondered why in the past that some cancer patients can but be impatient at slight illness in the face of death by calm face; oneself must be out of shape now and just know; what cancer was the most fearful is not death, but the unthinkable pain of ordinary person---not to depend merely on will with regard to patient pain." in the article according to " healthy Times " on April 3rd, 2003 relevant " cancer patient have the right to select for use narcotics ": according to statistics, the annual nearly 1,600,000 people's cancer strickens of China, 1,300,000 people die from cancer.Allow the cancer patient avoid pain and torment, become the sign of a national drug management policy and medical level.
Cancer pain has become the problem that the whole world is paid close attention to.The World Health Organization (WHO) just proposes the target of " allowing the cancer patient not bitterly in 2000 " and " three step analgesia schemes " (the oral administration mode of patient's long-term prescription is convenient in employing as far back as nineteen eighty-two, press the administration of pain degree ladder, administration on time and dose are the individuation of dosage of standard with the pain disappearance), the consumption of medical morphine as one of judgment criteria of cancer pain treatment level.Special medicine director Gu Weiping of place of security control department of National Drug Administration says: ... human society does not find the better analgesic that can replace morphine so far, morphine be the devil be again the angel, only otherwise flowing into illegal channels rationally is used on one's body the patient, just can effectively improve patient's quality of life.
In the whole world, particularly developing country suffers from other kind cancer numbers and also will increase sharply.Prediction address says that various cancers will cause 6,300,000 people's death every year, causing circulatory such as myocardial infarction, cerebral hemorrhage is died of illness will cause 5,300,000 people's death every year, because of the number of suffering from other chronic disease death will reach 2,500,000 people every year, the three adds up to annual dead about 2,450 ten thousand people of number.
Data shows that cancer overall annual progressive increase rate in the world's is 3%, and wherein sickness rate tool first place is gastric cancer and pulmonary carcinoma, and its annual progressive increase rate is respectively 10.5% and 10.4%; Secondly be knot, rectal cancer, annual progressive increase rate is 9%, the progressive increase rate of uterus carcinoma be 7.3% (and treatment women's genital cancer had tangible curative effect, as; Hysteromyoma, cervical cancer, carcinoma of uterine body, carcinoma vulvae, cancer of vagina and choriocarcinoma and carcinoma of fallopian tube and ovarian cancer, above-mentioned pact can account for 97% of female sexual organ cancer.), the progressive increase rate of oral cancer is 6%.The sickness rate of developed country's cancer is high more.According to statistics with regard to pathogenesis of cancer in general, the U.S. has increased by 1 training over nearly 25 years, and wherein pulmonary carcinoma has almost increased by 13 times; Japan has increased by 21% over nearly 10 years.The number that the man suffers from carcinoma of prostate will increase by 44%.Certainly developing country is no exception.
The inventor thinks after deliberation; Medicine is irremediable can use operative treatment, performs the operation irremediablely can use gene therapy, and gene is also controlled and bad can be used thermotherapy treatment, and thermotherapy is irremediable also just can't treat really.21 century is the century of biological heat medical engineering, and biological heat engineering in medicine technology has become the forward position and the commanding elevation of development innovation medical science and technology.Biological heat engineering in medicine The Application of Technology background is non-constant width thus.
The microwave electromagnetic field radiant energy is to intravital body fluid of people and the inherent heat energy of blood, magnetic energy, the static field energy, electric energy, microwave ultrasound, the sonochemistry energy, physical agents such as sound cavitation effect act on tissue, energy is by the intravital body fluid of people, tissue fluid, Cell sap, blood, absorptions such as lymph fluid, produce a series of electronics immediately, the biophysics, biochemistry, sonochemistry, physical and chemical reactions such as biomagnetism, then cause local and systemic physiological effect, play adjusting, keep, promote, kill sick cell, pain relieving, recover and strengthen various physiological functions (the most important thing is to strengthen and improve the immunologic function of self), reach the order ground that influences pathological process and health-care physiotherapeutic and rehabilitation disease.
From the angle of doctor trained in Western medicine, under the effect of " microwave electromagnetic field radiant energy ", the body temperature of human body will raise gradually, causes a series of physiology, the biochemical effect of body; Microcirculation is accelerated, and blood circulation quickens, and the thrombosis of heavy collection is pulverized in the blood vessel, level of adrenocortical hormone raises in the blood circulation, the level of antibody and immunoglobulin all will have more significantly and rise enhancing body histotrophic nutrition, blood circulation promoting and metabolism; Activating nervous system strengthens intravital fibroblast proliferation of people and enzyme and cytomegalic vigor, the raise immunity that speeds up of T cell maturation is quickened the accent of cell and is died, cause body that the resistance of disease is greatly improved, reach the poised state of regulating body.Simultaneously, the fighting capacity of the lymph among the WBC in the blood (leukocyte), neutral grain, mononuclear cell self is strengthened, opposing exopathogen ability strengthens can fully recover disease rapidly.All kinds of inflammatory lesions are had the control diffusion, promote Absorption that skin wound surface, all kinds of disunion wound and chronic surface ulcers etc. are had the repair that promotes granulation growth and epithelialization, except that heat effect, also have tangible non-thermal effect.The diseased region antibacterial of microwave radiation is effectively killed, and microcirculation improves, and tissue repair is accelerated, and has the strong effectively pain relieving and the effect of alleviating pain.Maximum characteristics are: can pulverize the thrombi in the cervical vertebra tremulous pulse under AT situation, in kill cancer cell or focus cell, microorganism, virus etc., replenish powerful " energy " can for normal cell of human body and tissue, human body and cell are not had any injury, are current up-to-date a kind of " green remedies ".
Motherland's medical science is thought: people's life is made of gas, blood, " the disconnected life of gas is died, and blood is to the greatest extent dead "." impairment of QI is pain then, and blood is hindered then swollen " gas hemopoietic, blood are fostered the spirit of nobility, and then health is safe, and all kinds of diseases and ailments are not given birth to, and longevity is prolonged life.Interior through last theory: " qi as the commander of blood, the capable then blood of gas is capable, the spontaneous recovery of QI and blood general rule disease ".Theory of Chinese medical science thinks that " general rule not bitterly, blood circulation promoting and blood stasis dispelling, heat-clearing and toxic substances removing, QI invigorating health preserving " is main, thereby reaches the rule of treatment of " attack heresy and just do not hinder, support and just and not helping heresy ".So-called just supporting is the balance of adjusting gas, blood and the body fluid of body by " No. 1, energy " with its distinctive " energy ".The defeated cloth of gas, blood and body fluid is fluent also to help resisting morbific exopathogen.According to this mechanism, utilize " No. 1, energy " to act on the potential that human body comes exciting human self, produce regulating QI and nourish blood, mediation is retarded by silt, thereby reach " self health care " physical therapy and mediation pathological changes meridians, reaching has a respite invigorates blood circulation, Yin Yang balancing, adjustment function, the disease of dispelling of curing the disease, the purpose of rehabilitation.
At present, known also do not have effective Therapeutic Method to cancer and cancer pain, more do not have the physiotherapy equipment of prevention, so the facility of developmental research prevention and treatment cancer and cancer pain is the task of top priority, and is imperative.
The inventor thinks through a large amount of research and clinical observation: medicine is irremediable can use operative treatment, perform the operation and irremediablely can use radiotherapy in the treatment, radiotherapy is irremediable can use gene therapy, gene is irremediable can use thermotherapy treatment, and thermotherapy is irremediable also just can't treat really.
Now, medical science both domestic and external is verified, and cancerous cell just can be killed by high temperature at 41 ℃, 120 minutes.But, when microwave thermal ray during for a long time to human body radiation, the temperature of body can rise, the juice pore of whole body all is opened, and blood vessel can be expanded, and blood can heat up thinning and accelerate flow velocity, at this moment body serious hydropenia part can occur, lack nutrition and anaerobic condition, can cause immunity to descend greatly, dehydration or collapse, stupor, heat shock, heart stop symptom such as beat will occur simultaneously, even can cause death.In other words, destroyed the ecological balance of human body, in fact this is an ideal target for this, is again a difficulty, not readily accessible target.Almost at present all thermotherapy biologists and technical specialist are struggling towards this target.This be at present worldwide microwave heat therapeutic can't be used for the long period and tumor is carried out the main bottleneck of whole-body hyperthermia.
The inventor studies with constantly the improvement of therapeutic device is declared 9 patented technologies of accepting by the inventor has constituted " energy-ecological balance " therapy-" high constant temperature hyperbaric oxygen bed microwave cancer heat preventive and thermal therapeutical equipment " promptly of the present invention through the clinical observation of more than ten years, comprises;
A kind of improved microwave therapy apparatus (1998.11.12) [98123655.3] { Invention Patent Entry matter examination procedure }
Microwave generator device-the inventor of microwave therapy apparatus, patentee; Chen Shaoyong
The applying date: (1998.12.9) patent No.: [ZL 98 2 49330.4] certificate number: " No. 358107 "
A kind of magnetron water-cooled cooling device-inventor of Synergistic and energy-saving, patentee; Chen Shaoyong
The applying date: (2002.11.7) patent No.: [ZL 01 2 73901.4] certificate number: " No. 525984 "
A kind of multifunction microwave boiler plant-inventor, patentee; Chen Shaoyong
The applying date: (2001.11.6) patent No.: [ZL 01 2 22044.2] certificate number: " No. 537843 "
A kind of microwave electromagnetic waves magnetic field instantaneous radiation drinking water and bathing stove and accessory-inventor, patentee; Chen Shaoyong
The applying date: (2001.11.8) patent No.: [ZL 01 2 73824.7] certificate number: " No. 537944 "
A kind of microwave heating hot-water heating-steam for heating is drunk multifunction electric cooker device-inventor, patentee; Chen Shaoyong
The applying date: (2001.11.11) patent No.: [ZL 01 2 73963.4] certificate number: " No. 541208 "
Treatment cover-inventor, the patentee of the external radiation hyperbaric oxygenation of a kind of microwave ultrasound; Chen Shaoyong
The applying date: (2001.11.13) patent No.: [ZL 01 2 73899.9] certificate number: " No. 536214 "
A kind of micro-nano mixing, stirring, magnetizing constant of medical oxygen therapy liquid (2001.12.25) [01145515.2]
Super mixing, stirring, magnetizing constant device-inventor, the patentee of new medical oxygen therapy liquid; Chen Shaoyong
The applying date: (2001.12.25) patent No.: [ZL 01 2 79960.2] certificate number: " No. 537463 "
Use " high constant temperature hyperbaric oxygen bed microwave cancer heat preventive and thermal therapeutical equipment " of the present invention when cancer pain patient is treated,treatment 3~10 times, just can effectively alleviate or remove cancer pain, and not re-use any analgesic drug product in each 60~120~240 minutes.And can be at 8 hours kill cancer cells.Simultaneously, also can be used for treating hypertension, sugared dung disease, cerebrovascular disease and lung, hepatopathy and hematologic disease.In addition, also can be used for treatment to AIDS, drug rehabilitation.Be that a kind of whole world is all at the prevention of effort developmental research and the facility of treatment cancer.During treatment human body is not had injury, not damaged, has no side effect, do not operate on, under the situation of no any misery cancerous cell killed and alleviates or remove cancer pain, be undoubtedly a kind of safer, more effective green remedy.Believe that the present invention will give the light of the happiness that vast sub-health population and cancer patient bring life.
The generation of cancer pain: if bone, muscle or nerve around the cancer infringement, thus various pain will appear in pressuring nerve.The chest pain that the esophageal carcinoma, pulmonary carcinoma occur, backache and lumbago appear in tumors of spinal cord etc., and stomachache etc. can appear in digestive tract cancer, female sexual organ cancer, and pain is not the distinctive symptom of cancer.When tumor being dwindled with microwave heat therapeutic, removed compressing to nerve, pain has also just been removed.
The technical solution adopted for the present invention to solve the technical problems is: the inventor is with " a kind of improved microwave therapy apparatus " application applying date: (1998.11.12) application number: [98123655.3] and " the microwave generator device of the microwave therapy apparatus " applying date: (1998.12.9) patent No.: [ZL 98 2 49330.4] certificate number: " No. 358107 " patented technology, and when being carried out clinical treatment, several routine cancer patients and hysteromyoma of gynecology patient find;
1, very effective to cancer pain and various treatment of pain effect; For cancer pain,, each one day, just can effectively alleviate or remove cancer pain, and not re-use any analgesic drug product in each 60~120~240minutes treatment 3~10 times.The generation of cancer pain: if bone, muscle or nerve around the cancer infringement, thus various pain will appear in pressuring nerve.The chest pain that the esophageal carcinoma, pulmonary carcinoma occur, backache and lumbago appear in tumors of spinal cord etc., and stomachache etc. can appear in digestive tract cancer, female sexual organ cancer, and pain is not the distinctive symptom of cancer.When tumor being dwindled with microwave heat therapeutic, removed compressing to nerve, pain has also just been removed.Can prove that thus if bitterly just do not illustrate that cancerous cell is controlled and killed, tumor mass has been dwindled, and has removed the compressing to nerve, pain has also just been removed.
For general various joint diseases, lumbago and skelalgia, treat once every day, and each 30~60 minutes, will to cure the time different with state of an illness needs not bitterly at once according to different people, can cure in 1~3 month.
2, when hysteromyoma of gynecology and tumor are carried out thermotherapy, find that the metal intrauterine contraceptive loop of the stainless system in fallopian tube can produce hyperpyrexia, the patient reacts pain.This has illustrated that resonant microwave of my invention has been radiated position darker in the body, is effective to the treatment tumor.If at fallopian tube and ovary canceration is being arranged, the high temperature that this eddy current that is produced by electromagnetic wave and metal resonance produces is can be effectively to the canceration for the treatment of this part.
3, when the women to some subhealth state prevents thermotherapy, when the microwave radiation head shone the place, uterus, they can react, and feel pain in the uterus.The inventor thinks that this is to have produced due to the pathological changes in the uterus, because be that blood can not circulate and the high temperature that produces, if unblocked blood flowing, blood will be taken away heat, also just can not heat accumulation.Consequently they have found that through ultrasound diagnosis intrauterine has muscular tumor to exist to hospital.Position to other is like this too, and in other words, microwave can be found some disease of being caused by poor blood circulation, as the lump of inside, little tumor mass etc.The intravital tumor of people equally also can be killed by high temperature because blood circulation is bad.
4, when the patient who some is had gastropathy carries out thermotherapy, find, when microwave radiation when the gastric area, the patient can constantly passwind, and finds after deliberation, this is because the negative pressure that high frequency oscillation produced of microwave and to due to the intensive wriggling of intestinal.This has brought hope for the not smooth people of treatment stool.And what is more important has been come the new method for the treatment of to intestinal adhesion and the intestinal ridge stopband that late period, the disease patient was produced.Such late period the disease patient treatment two examples, its effect is beat all good.
5, to some prostate and hemorrhoid patients usefulness sitting posture microwave heat therapeutic the time, when curing disease, the reactive function of patient has strengthened greatly.The inventor thinks after deliberation, and this is to have improved due to the blood circulation around the cloudy neck because of microwave heat therapeutic.
6, the cancer patient is being carried out long time during thermotherapy, it is boiling hotter that the patient reacts the upper and lower skin of chest.The inventor thinks after deliberation, has gone out a large amount of antiperspirant owing on the upper and lower skin, and microwave is to give birth to resonance and heat production with waterishlogging, so the temperature on the skin will be very high.After the sweat on the skin was wiped, skin had not just scalded.For this reason, the inventor has respectively connected a small fan at the micro-wave therapeutic head to the position of affected part thermotherapy upper and lower and has dispelled sweat on the skin in the present invention, guarantees thermotherapy effect.
7, my bed formula therapy apparatus of placing in the stateroom originally when treating to the patient, did not also go out antiperspirant at 30 minutes whole bodies, and I changed at a cubicle afterwards, and behind the closeall door and window, will the whole body dripping sweat less than 15 minutes patients.Think through inventor's research; When the microwave heating human body, the high temperature of human body can spread towards periphery, because high temperature can spread to the low temperature place.So, want that whole body is heated to 41~43 ℃ and be actually very difficult, at this moment, human body is actually a radiator.In treatment afterwards, I use an electric heater again, and the temperature of cubicle is heated to 41~42 ℃, and therapeutic effect significantly improves.Such purpose is that the temperature around making is higher than body temperature, makes the temperature of the affected area of human body reach the needed temperature of treatment in the shortest time, and it is important that this point causes the pass to kill cancer cell.For this reason, just adopted " high temperature constant temperature hyperbaric oxygen bed " device of heat-insulation and heat-preservation sealing in the present invention.Because be in the bed body of heat-insulation and heat-preservation sealing, thus necessary again supplemental oxygen, because need the long disposable cancerous cell (about 8 hours) of killing of time, just necessary energy needed, liquid nutritional or the beverage of replenishing.Because make a body inside reach 41~42 ℃, so just must increase the constant temperature circulating device system of electric hot water.
When actual the treatment, " the high temperature constant temperature hyperbaric oxygen bed " that " patient " (F) lies in sealing (E) provides hot water through " hot-water supply " in (A), (D) provide high pressure oxygen through " apparatus of oxygen supply " again, " monitor apparatus " (C) carries out security monitoring, (B2) (B3) health is added gentle constant temperature by " micro-wave therapeutic machine " " microwave whole-body hyperthermia head " (B) with " the ripe treatment head of microwave head ", (G) (H) (F) replenish necessary energy (oxygen and nutrient liquid) for " patient " with " nanometer blender patent " through " external respiration and benefit beverage device ", last reuse " the microwave tumor is killed the thermotherapy head " (B1) kills " patient " (F) intravital cancerous cell.
This invention comprise by " high temperature constant temperature hyperbaric oxygen bed " (A), " micro-wave therapeutic machine " (B), " monitor apparatus " (C), " apparatus of oxygen supply " (D), " hot-water supply " (E), " patient " (F), " external respiration with mend beverage device " (G) (H) constitute with " nanometer blender patent ".
Wherein, " high temperature constant temperature hyperbaric oxygen bed " (A) comprises by ' sealed bed body ' (a-1), ' sealing the mobile head of a bed ' (a-2), ' head of a bed block ' (a-3), ' sealing base ' (a-4), ' flexible hole pattern bed board ' (a-5), ' trapped orbit ' (a-6), ' slideway ' (a-7), ' inlet frame ' (a-8), ' head of a bed frame mouth ' (a-9), ' O-ring seal ' (a-10), ' hot water inlet pipe interface ' (a-11), ' return pipe interface ' (a-12), ' the antiperspirant fan gets on ' (a-13), ' the antiperspirant fan goes down ' (a-14), ' head seal is isolated soft honest and clean ' (a-15), ' neck running-on ' (a-16), ' elastic cover ' (a-17), ' horizontal filler strip ' (a-18), ' bed top sealing soft honest and clean ' (a-19), ' bed an end seal soft honest and clean ' (a-20), ' bed body limit slideway ' (a-21), ' sealing attacker ' (a-22), ' movable roof window ' (a-23), ' left movable window ' (a-24), ' right movable window ' (a-25), ' lamella lucida ' (a-26), ' opaque plate ' (a-27), ' bed body a left side sealed transparent plate ' (a-28), ' bed body right sealed transparent plate ' (a-29), ' bed body base plate ' (30).
" micro-wave therapeutic machine " (B) comprising: " the microwave tumor is killed the thermotherapy head " (B1), " microwave whole-body hyperthermia head " (B2), " microwave head thermotherapy head " (B3) constitute;
" the microwave tumor is killed the thermotherapy head " (B1) comprising: ' go up magnetron ' (b-1), ' go up lowering or hoisting gear ' (b-1-1), ' go up radiation shield ' (b-1-2), ' front and back slide rail ' (b-1-3), ' left and right sides slide rail ' (b-1-4), ' following magnetron ' (b-2), ' following lowering or hoisting gear ' (b-2-1), ' following radiation shield ' (b-2-2), ' microwave source electric appliance box ' (b-6), ' cooling water tank ' (b-7), ' cooling water pump ' (b-8), ' magnetron cooling water inlet pipe ' (b-9), ' magnetron cools back water pipe ' (b-10), ' magnetron power source line ' (b-11), ' pump switch ' (b-12), ' degree of lip-rounding treatment head framework ' (b-13), ' therapy apparatus base member case ' (b-14), ' radiation shield flexible mouthful ' (b-17);
The lowering or hoisting gear of magnetron: ' magnetron ' (b-1), ' negative electrode ' (0-0), ' supply socket ' (0-1), ' circular waveguide output seat ' (00), ' subbase ' (0-2), ' outer Luo stricture of vagina interface ' (0-3), ' Luo stricture of vagina ' (0-4), ' connection eyelet ' (0-5), ' connecting frame ' (0-6), ' ventilating duct ' (0-7) ' go up cooling fan ' (0-10), ' fan power supply line ' (0-9), ' going up lowering or hoisting gear ' (b-1-1) connect; ' go up lowering or hoisting gear ' (b-1-1) by ' rack shaft ' (0-11), ' gear shaft ' (0-12), ' rack ' (0-13), ' rocking handle ' (0-14) and ' fixing head ' (0-15) constitute;
" microwave whole-body hyperthermia head " (B2) comprising: ' go up magnetron ' (b-3), ' go up lowering or hoisting gear ' (b-3-1), ' go up radiation shield ' (b-3-2), ' following magnetron ' (b-4), ' following lowering or hoisting gear ' (b-4-1), ' following radiation shield ' (b-4-2), ' front and back slide rail ' (b-1-3), ' left and right sides slide rail ' (b-1-4), ' following magnetron ' (b-2), ' following lowering or hoisting gear ' (b-2-1), ' following radiation shield ' (b-2-2), ' microwave source electric appliance box ' (b-6), ' cooling water tank ' (b-7), ' cooling water pump ' (b-8), ' magnetron cooling water inlet pipe ' (b-9), ' magnetron cools back water pipe ' (b-10), ' magnetron power source line ' (b-11), ' pump switch ' (b-12), ' degree of lip-rounding treatment head framework ' (b-15), ' therapy apparatus base member case ' (b-16);
" microwave head thermotherapy head " (B3) comprising: ' head use magnetron ' (b-5), ' radiation shield ' (b-5-2), ' circular waveguide output seat ' (00), ' connecting frame ' (0-6), ' Connection Block ' (0-8), ' ventilating duct ' (0-7), ' last cooling fan ' (0-10), ' power line ' (0-9);
' water cooled magnetron ' (b-1), ' go up radiation shield ' (b-1-2), ' cooling water inlet adapter ' (Q1), ' adapter of cooling water backwater ' (Q2), ' manual lifting device ' (B00-1), ' Motorized lift device ' (B00-2), ' hydraulic lift ' (B00-3);
The lowering or hoisting gear of magnetron comprise by: ' magnetron ' (b-1), ' negative electrode ' (0-0), ' supply socket ' (0-1), ' circular waveguide output seat ' (00), ' subbase ' (0-2), ' outer Luo stricture of vagina interface ' (0-3), ' Luo stricture of vagina ' (0-4), ' connection eyelet ' (0-5), ' connecting frame ' (0-6), ' ventilating duct ' (0-7) ' go up cooling fan ' (0-10), ' fan power supply line ' (0-9), ' going up lowering or hoisting gear ' (b-1-1) connect; ' go up lowering or hoisting gear ' (b-1-1) by ' rack shaft ' (0-11), ' gear shaft ' (0-12), ' rack ' (0-13), ' rocking handle ' (0-14) and ' fixing head ' (0-15) constitute;
" apparatus of oxygen supply " (D) comprise by; ' medical oxygen cylinder ' (d-1), ' oxygen supply valve ' (d-2), ' oxygen gauge ' (d-3), ' oxygen supply pipe ' (d-4), ' hyperbaric oxygen bed oxygen supply inlet connection ' (d-5) constitute.
" hot-water supply " (E) comprise by, ' electric heater ' (e-1), ' feed pipe ' (e-2), ' feed water valve ' (e-3), ' heat supply water lines ' (e-4), ' heat supply water pump ' (e-5), ' pump heat supply water pipe ' (e-6), ' advance radiator take over ' (e-7), ' bed inner radiator ' (e-8), ' return pipe ' (e-9), ' back water pump ' (e-10), ' return pipe ' (e-11) constitute;
" monitor apparatus " (C) comprise by ' temperature control instrument ' (c-1), ' temperature control sensor ' (c-2), ' bed body in oxygen gauge ' (c-3), ' oxygen sensor in the bed body ' (c-4), ' oxygen gauge in the head of a bed ' (c-5), ' oxygen sensor in the head of a bed ' (c-6), ' human body temperature monitoring form ' (c-7), ' temperature sensor for human body ' (c-8) constitute;
" external respiration with mend beverage device " (G) comprise by, ' gas inhaler device ' (g-1), ' inhaler nose cup ' (g-2), ' fluid infusion input pipe ' (g-3), ' mouth inhaler ' (g-4), ' liquid supplementation pipe ' (g-5), ' oxygen input tube ' (g-6), ' liquid input tube ' (g-7), ' head of a bed oxygen supply inlet connection ' (g-8);
" nanometer blender patent " (H), ' nanometer blender patent ' (h-1)
' instrument and meter ' (j-5), ' microwave display lamp ' (j-6), ' microwave display lamp ' (j-7) ' microwave display lamp ' (j-10),
' patient ' (f-1), ' carcinoma position ' (f-2).
The invention has the beneficial effects as follows, the invention provides a kind of " high constant temperature hyperbaric oxygen bed microwave cancer heat preventive and thermal therapeutical equipment ", when cancer pain patient is treated,treatment 3~10 times, just can effectively alleviate or remove cancer pain in each 60~240 minutes, do not re-use any analgesic drug product, and can be at 8 hours kill cancer cells.Simultaneously, also can be used for treating hypertension, sugared dung disease, cerebrovascular disease and lung, hepatopathy and hematologic disease.In addition, also can be used for treatment to AIDS, drug rehabilitation.Be that a kind of whole world is all at the prevention of effort developmental research and the facility of treatment cancer.During treatment human body is not had injury, does not take medicine, has no side effect, do not operate on, under the situation of no any misery cancerous cell killed and alleviates or remove cancer pain, be undoubtedly a kind of safer, more effective green remedy.Believe that the present invention will give the light of the happiness that vast sub-health population and cancer patient bring life.
Description of drawings
The present invention is further described below in conjunction with drawings and Examples:
Fig. 1~Fig. 2 is the structural diagrams of the present invention's " high constant temperature hyperbaric oxygen bed microwave cancer heat preventive and thermal therapeutical equipment ";
Fig. 3 is " apparatus of oxygen supply " of the present invention technological process diagram;
Fig. 4 is " hot-water supply " of the present invention technological process diagram;
Fig. 5~Fig. 6 is " high temperature constant temperature hyperbaric oxygen bed " of the present invention cut-away view when opening and sealing;
Fig. 7~Fig. 8 is " micro-wave therapeutic machine " of the present invention cut-away view during to patient treatment;
Fig. 9~Figure 10 is that " micro-wave therapeutic machine " of the present invention structure cut-away view is separated;
Figure 11 is " micro-wave therapeutic machine " of the present invention structure cut-away view when opening;
Figure 12 is the diagram in the cross section of " micro-wave therapeutic machine " of the present invention;
Figure 13~Figure 16 is the moving track structural diagrams of " micro-wave therapeutic machine " of the present invention;
Figure 17~Figure 19 is ' sealing the mobile head of a bed ' of the present invention structure cut-away view;
Figure 20~Figure 22 is ' sealed bed body ' of the present invention and ' flexible hole pattern bed board ' structural diagrams;
Figure 23~Figure 24 is the soft honest and clean structural diagrams of sealing of ' sealed bed body ' of the present invention above and below;
Figure 25~Figure 26 is the diagram of going the antiperspirant fan to be connected with radiator in ' sealed bed body ' of the present invention;
Figure 27~Figure 28 is a magnetron structures diagram of the present invention;
Figure 29~Figure 30 is the structural diagrams of circular waveguide output seat of the present invention;
Figure 31~Figure 33 is a magnetron of the present invention and the diagram that is connected of radiation shield and heat sink;
Figure 34~Figure 36 is the diagram that magnetron of the present invention is connected with radiation shield, heat sink and lowering or hoisting gear;
Figure 37 is the structural diagrams of water cooled magnetron heat sink of the present invention and manual lifting device;
Figure 38 is the structural diagrams of magnetron connection of the present invention and Motorized lift device;
Figure 39 is the structural diagrams of the hydraulic lift of magnetron of the present invention.
Among the figure, A. " high temperature constant temperature hyperbaric oxygen bed ", B. " micro-wave therapeutic machine ", C. " monitor apparatus ", D. " apparatus of oxygen supply ", E. " hot-water supply ", F. " patient ", G. " external respiration and benefit beverage device ", H. " nanometer blender patent ".
Wherein, A. " high temperature constant temperature hyperbaric oxygen bed " comprises by a-1. ' sealed bed body ', a-2. ' seal the mobile head of a bed ', a-3. ' head of a bed block ', a-4. ' sealing base ', a-5. ' flexible hole pattern bed board ', a-6. ' trapped orbit ', a-7. ' slideway ', a-8. ' inlet frame ', a-9. ' head of a bed frame mouth ', a-10. ' O-ring seal ', a-11. ' hot water inlet pipe interface ', a-12. ' return pipe interface ', a-13. ' the antiperspirant fan gets on ', a-14. ' the antiperspirant fan goes down ', a-15. ' head seal is isolated soft honest and clean ', a-16. ' neck running-on ', a-17. ' elastic cover ', a-18. ' horizontal filler strip ', a-19. ' sealing of bed top is soft honest and clean ', a-20. ' the bed end, seal soft honest and clean ', a-21. ' bed body limit slideway ', a-22. ' sealing attacker ', a-23. ' movable roof window ', a-24. ' left movable window ', a-25. ' right movable window ', a-26. ' lamella lucida ', a-27. ' opaque plate ', a-28. ' bed body left side sealed transparent plate ', a-29. ' the right sealed transparent plate of bed body ', a-30. ' bed body base plate ' constitutes.
B. " micro-wave therapeutic machine " comprising: B1. " the microwave tumor is killed the thermotherapy head ", B2. " microwave whole-body hyperthermia head ", B3. " microwave head thermotherapy head " constitute.
B1. " the microwave tumor is killed the thermotherapy head " comprising: b-1. ' goes up magnetron ', b-1-1. ' go up lowering or hoisting gear ', b-1-2. ' go up radiation shield ', b-1-3. ' front and back slide rail ', b-1-4. ' left and right sides slide rail ', b-2. ' following magnetron ', b-2-1. ' following lowering or hoisting gear ', b-2-2. ' following radiation shield ', b-6. ' microwave source electric appliance box ', b-7. ' cooling water tank ', b-8. ' cooling water pump ', b-9. ' magnetron cooling water inlet pipe ', b-10. ' magnetron cools back water pipe ', b-11. ' magnetron power source line ', b-12. ' pump switch ', b-13. ' degree of lip-rounding treatment head framework ', b-14. ' therapy apparatus base member case ', b-17. ' flexible mouthful of radiation shield ';
The lowering or hoisting gear of magnetron comprises: b-1. ' magnetron ', 0-0. ' negative electrode ', 0-1. ' supply socket ', 00. ' circular waveguide output seat ', 0-2. ' subbase ', the outer Luo stricture of vagina of 0-3. ' interface ', 0-4. ' Luo stricture of vagina ', 0-5. ' connection eyelet ', 0-6. ' connecting frame ', 0-7. ' ventilating duct ', 0-10. ' go up cooling fan ', 0-9. ' fan power supply line ';
B-1-1. ' go up lowering or hoisting gear ' is by 0-11. ' rack shaft ', 0-12. ' gear shaft ', 0-13. ' rack ', 0-14. ' rocking handle ', 0-15. ' fixing head ' (0-15) constitute.
B2. " microwave whole-body hyperthermia head " comprising: b-3. ' goes up magnetron ', b-3-1. ' go up lowering or hoisting gear ', b-3-2. ' go up radiation shield ', the following magnetron of b-4. ' ', the following lowering or hoisting gear of b-4-1. ' ', the following radiation shield of b-4-2. ' ', b-1-3. ' front and back slide rail ', b-1-4. ' left and right sides slide rail ', b-15. ' degree of lip-rounding treatment head framework ', b-16. ' therapy apparatus base member case ';
B3. " microwave head thermotherapy head " comprising: b-5. ' head magnetron ', b-5-2. ' radiation shield ', 00. ' circular waveguide output seat ', 0-6. ' connecting frame ', 0-8. ' Connection Block ', 0-7. ' ventilating duct ', the last cooling fan of 0-10. ' ', 0-9. ' power line ';
B-1. ' water cooled magnetron ', b-1-2. ' go up radiation shield ', Q1. ' cooling water inlet take over ', Q2. ' cooling water backwater takes over ', B00-1. ' manual lifting device ', B00-2. ' Motorized lift device ', B00-3. ' hydraulic lift ';
The lowering or hoisting gear of magnetron: b-1. ' magnetron ', 0-0. ' negative electrode ', 0-1. ' supply socket ', 00. ' circular waveguide output seat ', 0-2. ' subbase ', the outer Luo stricture of vagina of 0-3. ' interface ', 0-4. ' Luo stricture of vagina ', 0-5. ' connection eyelet ', 0-6. ' connecting frame ', 0-7. ' ventilating duct ', 0-10. ' go up cooling fan ', 0-9. ' fan power supply line ';
B-1-1. ' go up lowering or hoisting gear ' is by 0-11. ' rack shaft ', 0-12. ' gear shaft ', 0-13. ' rack ', 0-14. ' rocking handle ' and 0-15. ' fixing head ' formation;
D. " apparatus of oxygen supply " comprise by; D-1. ' medical oxygen cylinder ', d-2. ' oxygen supply valve ', d-3. ' oxygen gauge ', d-4. ' oxygen supply pipe ', d-5. ' hyperbaric oxygen bed oxygen supply inlet connection ';
C. " monitor apparatus " comprises by c-1. ' temperature control instrument ', c-2. ' temperature control sensor ', oxygen gauge in the oxygen gauge in c-3. ' the bed body ', c-4. ' bed body in oxygen sensor ', the c-5. ' head of a bed ', the c-6. ' head of a bed in oxygen sensor ', c-7. ' human body temperature monitoring form ', c-8. ' temperature sensor for human body ';
G. " external respiration with mend beverage device " comprises by, g-1. ' gas inhaler device ', g-2. ' inhaler nose cup ', g-3. ' fluid infusion input pipe ', g-4. ' mouth inhaler ', g-5. ' liquid supplementation pipe ', g-6. ' oxygen input tube ', g-7. ' liquid input tube ', g-8. ' head of a bed oxygen supply inlet connection ';
H. " nanometer blender patent ", h-1. ' nanometer blender patent ';
F-1. ' patient ', f-2. ' carcinoma position ';
J-5. ' instrument and meter ', j-6. ' microwave display lamp ', j-7. ' microwave display lamp ', j-10. ' microwave display lamp '
The specific embodiment
In Fig. 1~Fig. 2, the present invention be by; " high temperature constant temperature hyperbaric oxygen bed " (A), " micro-wave therapeutic machine " (B), " monitor apparatus " (C), " apparatus of oxygen supply " (D), " hot-water supply " (E), " patient " (F), " external respiration with mend beverage device " (G) and " nanometer blender patent " (H) constitute.
" micro-wave therapeutic machine " (B) comprise by resonant " the microwave tumor is killed the thermotherapy head " of: double end (B1), resonant " the microwave whole-body hyperthermia head " of double end (B2), " microwave head thermotherapy head " (B3) constitute.
In Fig. 3, be " apparatus of oxygen supply " of the present invention (D) system;
" apparatus of oxygen supply " (D) comprise by; ' medical oxygen cylinder ' ' oxygen supply valve ' on (d-1) (d-2) with ' oxygen gauge ' (d-3), through ' oxygen supply pipe ' (d-4) be connected ' hyperbaric oxygen bed oxygen supply inlet connection ' (d-5) and enter " high temperature constant temperature hyperbaric oxygen bed " (A) in, " patient " (F) with resonant " the microwave whole-body hyperthermia head " of double end (B2), " microwave head thermotherapy head " (B3) carry out the thermotherapy of whole body, when body temperature reaches required treatment temperature, (B1) kill cancerous cell by " the microwave tumor is killed the thermotherapy head " that double end is resonant;
" the monitor apparatus " that " high temperature constant temperature hyperbaric oxygen bed " connecting on (A) (C) comprise by ' temperature control instrument ' (c-1), ' temperature control sensor ' (c-2), ' oxygen gauge in the bed body ' (c-3), ' oxygen sensor in the bed body ' (c-4), ' oxygen gauge in the head of a bed ' (c-5), ' oxygen sensor in the head of a bed ' (c-6), ' human body temperature monitoring form ' (c-7), ' temperature sensor for human body ' (c-8).
In Fig. 4, be " hot-water supply " of the present invention (E) system;
" hot-water supply " (E) comprises, (e-2) (e-3) (e-1) be connected by ' feed pipe ' with ' electric heater ' through ' feed water valve ', and ' heat supply water lines ' that warp ' electric heater ' (e-1) upward connects (e-4), ' heat supply water pump ' (e-5), ' pump heat supply water pipe ' (e-6) through ' advance radiator take over ' (e-7) be connected to " high temperature constant temperature hyperbaric oxygen bed " ' bed inner radiator ' in (A) (e-8) advance the hot-water line interface, through ' bed inner radiator ' (e-8) with ' return pipe ' of the other end (e-9), ' back water pump ' (e-10), ' return pipe ' (e-11) connects, and is back to ' electric heater ' (e-1) complete hot water circuit process system of interior formation.And " high temperature constant temperature hyperbaric oxygen bed " connecting on (A) ' temperature control instrument ' (c-1) with ' temperature control sensor ' (c-2).
In Fig. 5~Fig. 6, " high temperature constant temperature hyperbaric oxygen bed " (A) comprise by; ' the sealed bed body ' made with the heat-insulation and heat-preservation material (a-1), ' sealing base ' (a-4), ' trapped orbit ' (a-6), ' inlet frame ' (a-8) be linked in sequence, ' hot water inlet pipe interface ' (a-11) with " high temperature constant temperature hyperbaric oxygen bed " ' bed inner radiator ' in (A) (e-8), ' return pipe interface ' (a-12) be connected; And ' sealed bed body ' connecting in (a-1) ' the antiperspirant fan gets on ' (a-13) and ' the antiperspirant fan goes down ' (a-14); ' head of a bed frame mouth ' of ' the sealing the mobile head of a bed ' of moving with the scalable combination that ' sealed bed body ' (a-1) is connected on (a-2) connecting ' O-ring seal ' on (a-9) and (a-10) and ' sealing the mobile head of a bed ' (a-2) is being connected ' flexible hole pattern bed board ' (a-5) with ' head of a bed frame mouth ' in (a-9); ' sealing the mobile head of a bed ' (a-2) with ' head of a bed frame mouth ' be connected below (a-9) ' head of a bed block ' (a-3) and ' slideway ' (a-7).
In Fig. 7~Fig. 8, " micro-wave therapeutic machine " (B) comprise by: ' going up magnetron ' that " the microwave tumor is killed the thermotherapy head " connects in (B1) (b-1) and ' following magnetron ' ' upward magnetron ' of (b-2) being connected in (B2) with " microwave whole-body hyperthermia head " (b-3) (b-4) reach ' magnetron ' that " microwave head thermotherapy head " be connected in (B3) and (b-5) (b-6) constitute with ' microwave source electric appliance box ' with ' following magnetron ';
Connecting a cover " microwave head thermotherapy head " in (a-2) " high temperature constant temperature hyperbaric oxygen bed " ' sealing the mobile head of a bed ' (A) (B3) installs; And " high temperature constant temperature hyperbaric oxygen bed " ' sealed bed body ' (A) (a-1) on respectively by adorning ' going up magnetron ' that " the microwave tumor is killed the thermotherapy head " connect in (B1) (b-1) and ' following magnetron ' ' last magnetron ' of (b-2) being connected in (B2) with " microwave whole-body hyperthermia head " (b-3) and ' following magnetron ' (b-4);
And ' sealing the mobile head of a bed ' (a-2) be connected in (a-9) with ' head of a bed frame mouth ' ' flexible hole pattern bed board ' (a-5) above recumbency ' patient ' that be carried out treatment (f-1) (a-2) be connected ' head of a bed block ' ' slideway ' on (a-3) below (a-9) and (a-7) passing in and out ' sealed bed body ' (a-1) mobile in orbit with ' head of a bed frame mouth ' by ' sealing the mobile head of a bed ';
' sealing the mobile head of a bed ' connecting on (a-2) by ' gas inhaler device ' (g-1), ' inhaler nose cup ' (g-2), ' fluid infusion input pipe ' (g-3), ' mouth inhaler ' (g-4), ' nanometer blender patent ' (h-1), ' liquid supplementation pipe ' (g-5), ' oxygen input tube ' (g-6), ' liquid input tube ' (g-7), ' head of a bed oxygen supply inlet connection ' " external respiration with mend beverage device " of (g-8) forming (G).
Among Fig. 9, Figure 10 and Figure 11, connecting a cover " microwave head thermotherapy head " in (a-2) " high temperature constant temperature hyperbaric oxygen bed " ' sealing the mobile head of a bed ' (A) and (B3) installing; And " high temperature constant temperature hyperbaric oxygen bed " ' sealed bed body ' (A) (a-1) on respectively by adorning ' going up magnetron ' that " the microwave tumor is killed the thermotherapy head " connect in (B1) (b-1) and ' following magnetron ' ' last magnetron ' of (b-2) being connected in (B2) with " microwave whole-body hyperthermia head " (b-3) and ' following magnetron ' (b-4);
And ' sealing the mobile head of a bed ' (a-2) be connected in (a-9) with ' head of a bed frame mouth ' ' flexible hole pattern bed board ' (a-5) above recumbency ' patient ' that be carried out treatment (f-1) (a-2) be connected ' head of a bed block ' ' slideway ' on (a-3) below (a-9) and (a-7) passing in and out ' sealed bed body ' (a-1) mobile in orbit with ' head of a bed frame mouth ' by ' sealing the mobile head of a bed ';
' sealed bed body ' (a-1) with combination ' sealing the mobile head of a bed ' be connected on (a-2) ' head of a bed frame mouth ' (a-9), ' O-ring seal ' (a-10), ' head seal is isolated soft honest and clean ' (a-15), ' neck running-on ' (a-16) and ' elastic cover ' (a-17);
" micro-wave therapeutic machine " (B) comprises that ' going up magnetron ' of being connected in (b-13) by: " the microwave tumor is killed the thermotherapy head " metal ' degree of lip-rounding treatment head framework ' on (B1) (b-1), ' go up lowering or hoisting gear ' (b-1-1), ' go up radiation shield ' (b-1-2) and ' following magnetron ' (b-2), ' following lowering or hoisting gear ' (b-2-1), ' following radiation shield ' (b-2-2), ' microwave source electric appliance box ' (b-6) (b-14) reaches ' front and back slide rail ' (b-1-3) with ' therapy apparatus base member case ', ' left and right sides slide rail ' (b-1-4) constitutes " the microwave tumor is killed the thermotherapy head " (B1);
' going up magnetron ' of being connected in (b-15) by " microwave whole-body hyperthermia head " metal ' degree of lip-rounding treatment head framework ' on (B2) (b-3), ' go up lowering or hoisting gear ' (b-1-1), ' go up radiation shield ' (b-1-2) and ' following magnetron ' (b-4), ' following lowering or hoisting gear ' (b-2-1), ' following radiation shield ' (b-2-2), ' microwave source electric appliance box ' (b-6) with ' therapy apparatus base member case ' (b-16) and ' the front and back slide rail ' that be connected (b-2-3), ' left and right sides slide rail ' (b-2-4) constitutes " microwave whole-body hyperthermia head " (B2);
" microwave head thermotherapy head " (B3); By be connected ' sealing the mobile head of a bed ' ' magnetron ' in (a-2) (b-5), ' radiation shield ' (b-5-2) with ' microwave source electric appliance box ' on ' instrument and meter ' that be connected (j-5), ' microwave display lamp ' (j-10) (a-3) constitute with ' mobile base '.
" external respiration with mend beverage device " (G) comprise by, ' patient ' (f-1), ' carcinoma position ' (f-2) with ' gas inhaler device ' (g-1), ' inhaler nose cup ' (g-2), ' fluid infusion input pipe ' (g-3), ' mouth inhaler ' (g-4), " nanometer blender patent " (H), ' nanometer blender patent ' (h-1), ' liquid supplementation pipe ' (g-5), ' oxygen input tube ' (g-6), ' liquid input tube ' (g-7), ' head of a bed oxygen supply inlet connection ' (g-8) form.
Among Figure 12~Figure 16, " high temperature constant temperature hyperbaric oxygen bed " (A) comprises by ' sealed bed body ' (a-1), ' sealing base ' (a-4), ' flexible hole pattern bed board ' (a-5), ' trapped orbit ' (a-6), ' slideway ' (a-7), ' inlet frame ' (a-8), ' hot water inlet pipe interface ' (a-11), ' return pipe interface ' (a-12), ' the antiperspirant fan gets on ' (a-13), ' the antiperspirant fan goes down ' (a-14), ' horizontal filler strip ' (a-18), ' bed top sealing soft honest and clean ' (a-19), ' bed an end seal soft honest and clean ' (a-20), ' bed body limit slideway ' (a-21) constitutes;
" the microwave tumor is killed the thermotherapy head " (B1) comprising: ' going up magnetron ' of connecting in (b-13) in metal ' degree of lip-rounding treatment head framework ' (b-1), ' go up lowering or hoisting gear ' (b-1-1), ' go up radiation shield ' (b-1-2), ' following magnetron ' (b-2), ' following lowering or hoisting gear ' (b-2-1), ' following radiation shield ' (b-2-2) with ' cooling water tank ' (b-7), ' cooling water pump ' (b-8), ' magnetron cooling water inlet pipe ' (b-9), ' magnetron cools back water pipe ' (b-10), ' magnetron power source line ' (b-11), ' pump switch ' (b-12) and ' therapy apparatus base member case ' ' microwave source electric appliance box ' in (b-14) (b-6) and ' front and back slide rail ' (b-1-3), ' left and right sides slide rail ' (b-1-4) constitutes, and ' degree of lip-rounding treatment head framework ' (b-13) go up connect ' flexible mouthful of radiation shield ' (b-17) with ' microwave display lamp ' (j-6), ' microwave display lamp ' (j-7).
In Figure 17~Figure 19, connecting in (a-2) ' the sealing the mobile head of a bed ' made from the heat-insulation and heat-preservation material ' head magnetron ' (b-5) with ' radiation shield ' (b-5-2) and ' sealing the mobile head of a bed ' be connected in (a-2) can ' sealed bed body ' (a-1) in telescopic moving ' the hole pattern bed board stretches ' (a-5); ' at the mobile head of a bed of sealing ' connecting on (a-2) ' head of a bed frame mouth ' (a-9), ' O-ring seal ' (a-10), ' head seal is isolated soft honest and clean ' (a-15), ' neck running-on ' (a-16), ' elastic cover ' be equipped with by adorning (a-17) and on ' at the mobile head of a bed of sealing ' ' lamella lucida ' ' movable roof window ' (a-26) (a-23), ' left movable window ' (a-24) with ' right movable window ' (a-25); ' at the mobile head of a bed of sealing ' bottom (a-2) connect by be equipped with ' opaque plate ' ' head of a bed block ' (a-27) (a-3) and ' slideway ' (a-7); ' head of a bed block ' connecting on (a-3) ' instrument and meter ' (j-5) and ' microwave display lamp ' (j-10).
In Figure 20~Figure 22, connecting ' chute ' (a-28) on ' sealed bed body ' both sides in (a-1), ' chute ' that connects in (a-8) by ' sealed bed body ' ' inlet frame ' (a-1) (a-28) in by adorning scalable mobile having ' bed body limit slideway ' ' flexible hole pattern bed board ' (a-21) (a-5); ' flexible hole pattern bed board ' is the bed board that is compiled into the Tou Guoed oxygen of grid-shaped with nylon rope (a-5); ' sealed bed body ' two faces (a-1) are by ' lamella lucida ' heat insulation wall window (a-26) is housed.
In Figure 23~Figure 24, ' sealed bed body ' (a-1) bed top and ' bed body base plate ' (30) on be connected transparent air-locked ' sealing of bed top is soft honest and clean ' (a-19) and ' the bed end, seal soft honest and clean ' (a-20) two faces be connected air-locked ' bed body left side sealed transparent plate ' that (a-26) connects by ' lamella lucida ' (a-28) with ' a body right side sealed transparent plate ' (a-29).
In Figure 25~Figure 26, ' sealed bed body ' ' flexible hole pattern bed board ' in (a-1) (a-5) above and following be connected respectively ' the antiperspirant fan gets on ' (a-13) (a-14) and at ' sealed bed body ' ' inlet frame ' (a-1) (a-8) be connected ' sealing the attacker ' on the limit (a-22) with ' the antiperspirant fan goes down ', connecting ' inner radiator ' (e-8) at ' sealed bed body ' in (a-1).
In Figure 27~Figure 28, for ' magnetron ' ' negative electrode ' on (b-1) (0-0) with ' supply socket ' (0-1).
In Figure 29~Figure 30, for being used for connecting ' magnetron ' ' circular waveguide output seat ' (00) (b-1); Metal ' circular waveguide output seat ' (00) comprise by ' subbase ' (0-2), ' outer Luo stricture of vagina interface ' (0-3), ' Luo stricture of vagina ' (0-4), ' connection eyelet ' (0-5) constitute; ' magnetron ' (b-1) can select 250W~950W for use.
In Figure 31, Figure 32 and Figure 33, (B-5-2) be connected with ' going up radiation shield ' through ' circular waveguide output seat ' (00) in ' going up magnetron ' lower end (b-5); In ' go up magnetron ' upper end (b-5) through ' connecting frame ' (0-6) be linked in sequence ' Connection Block ' ' ventilating duct ' in (0-8) (0-7) connects ' last cooling fan ' (0-10) and ' power line ' (0-9); ' going up cooling fan ' (0-10) can select 80W~120W.
In Figure 34, Figure 35 and Figure 36, ' following magnetron ' upper end (b-1) is connecting ' following radiation shield ' (b-1-2) through ' circular waveguide output seat ' (00); ' following magnetron ' lower end (b-1) (0-6) (0-7) (0-10) (0-9) reaches ' following lowering or hoisting gear ' with ' fan power supply line ' with ' following cooling fan ' in order with ' ventilating duct ' through ' connecting frame ' and (b-1-1) is connected; ' following lowering or hoisting gear ' (b-1-1) by ' rack shaft ' (0-11), ' gear shaft ' (0-12), ' rack ' (0-13), ' rocking handle ' (0-14) and ' fixing head ' (0-15) constitute, and (0-15) be connected with body by ' fixing head '.
In Figure 37, ' water cooled magnetron ' end (b-1) connecting ' cooling water inlet adapter ' (Q1) other end connecting ' adapter of cooling water backwater ' (Q2); And connecting ' going up radiation shield ' in ' water cooled magnetron ' lower end (b-1) and (b-1-2) connecting ' manual lifting device ' (B00-1) in the upper end.
In Figure 38, connecting ' going up radiation shield ' in ' water cooled magnetron ' lower end (b-1) and (b-1-2) connecting ' Motorized lift device ' (B00-2) in the upper end.
In Figure 39, connecting in ' magnetron ' lower end (b-1) ' go up radiation shield ' (b-1-2) upper end connect ' hydraulic lift ' (B00-3), ' cooling fan ' (0-10), ' ventilating duct ' (0-7).

Claims (9)

1. one kind high constant temperature hyperbaric oxygen bed microwave cancer heat preventive and thermal therapeutical equipment, this invention comprise by " high temperature constant temperature hyperbaric oxygen bed " (A), " micro-wave therapeutic machine " (B), " monitor apparatus " (C), " apparatus of oxygen supply " (D), " hot-water supply " (E), " external respiration with mend beverage device " (G) (H) constitute with " nanometer blender patent "; " high temperature constant temperature hyperbaric oxygen bed " (A) comprises by ' sealed bed body ' (a-1), ' sealing the mobile head of a bed ' (a-2), ' head of a bed block ' (a-3), ' sealing base ' (a-4), ' flexible hole pattern bed board ' (a-5), ' trapped orbit ' (a-6), ' slideway ' (a-7), ' inlet frame ' (a-8), ' head of a bed frame mouth ' (a-9), ' O-ring seal ' (a-10), ' hot water inlet pipe interface ' (a-11), ' return pipe interface ' (a-12), ' the antiperspirant fan gets on ' (a-13), ' the antiperspirant fan goes down ' (a-14), ' head seal is isolated soft honest and clean ' (a-15), ' neck running-on ' (a-16), ' elastic cover ' (a-17), ' horizontal filler strip ' (a-18), ' bed top sealing soft honest and clean ' (a-19), ' bed an end seal soft honest and clean ' (a-20), ' bed body limit slideway ' (a-21), ' sealing attacker ' (a-22), ' movable roof window ' (a-23), ' left movable window ' (a-24), ' right movable window ' (a-25), ' lamella lucida ' (a-26), ' opaque plate ' (a-27), ' bed body a left side sealed transparent plate ' (a-28), ' bed body right sealed transparent plate ' (a-29), ' bed body base plate ' (30), ' chute ' (a-31) constitutes; " micro-wave therapeutic machine " (B) comprise by: " the microwave tumor is killed the thermotherapy head " (B1), " microwave whole-body hyperthermia head " (B2), " microwave head thermotherapy head " (B3) constitute; " the microwave tumor is killed the thermotherapy head " (B1) comprise by: ' go up magnetron ' (b-1), ' go up lowering or hoisting gear ' (b-1-1), ' go up radiation shield ' (b-1-2), ' front and back slide rail ' (b-1-3), ' left and right sides slide rail ' (b-1-4), ' following magnetron ' (b-2), ' following lowering or hoisting gear ' (b-2-1), ' following radiation shield ' (b-2-2), ' microwave source electric appliance box ' (b-6), ' cooling water tank ' (b-7), ' cooling water pump ' (b-8), ' magnetron cooling water inlet pipe ' (b-9), ' magnetron cools back water pipe ' (b-10), ' magnetron power source line ' (b-11), ' pump switch ' (b-12), ' degree of lip-rounding treatment head framework ' (b-13), ' therapy apparatus base member case ' (b-14), ' flexible mouthful of radiation shield ' (b-17) constitutes; " microwave whole-body hyperthermia head " (B2) comprise by: ' go up magnetron ' (b-3), ' go up lowering or hoisting gear ' (b-3-1), ' go up radiation shield ' (b-3-2), ' following magnetron ' (b-4), ' following lowering or hoisting gear ' (b-4-1), ' following radiation shield ' (b-4-2), ' front and back slide rail ' (b-1-3), ' left and right sides slide rail ' (b-1-4), ' following magnetron ' (b-2), ' following lowering or hoisting gear ' (b-2-1), ' following radiation shield ' (b-2-2), ' microwave source electric appliance box ' (b-6), ' cooling water tank ' (b-7), ' cooling water pump ' (b-8), ' magnetron cooling water inlet pipe ' (b-9), ' magnetron cools back water pipe ' (b-10), ' magnetron power source line ' (b-11), ' pump switch ' (b-12), ' degree of lip-rounding treatment head framework ' (b-15), ' therapy apparatus base member case ' (b-16) constitutes; " microwave head thermotherapy head " (B3) comprise by: ' head use magnetron ' (b-5), ' radiation shield ' (b-5-2), ' circular waveguide output seat ' (00), ' connecting frame ' (0-6), ' Connection Block ' (0-8), ' ventilating duct ' (0-7), ' last cooling fan ' (0-10), ' power line ' (0-9) constitute; " apparatus of oxygen supply " (D) comprise by; ' medical oxygen cylinder ' (d-1), ' oxygen supply valve ' (d-2), ' oxygen gauge ' (d-3), ' oxygen supply pipe ' (d-4), ' hyperbaric oxygen bed oxygen supply inlet connection ' (d-5) constitute; " hot-water supply " (E) comprise by, ' electric heater ' (e-1), ' feed pipe ' (e-2), ' feed water valve ' (e-3), ' heat supply water lines ' (e-4), ' heat supply water pump ' (e-5), ' pump heat supply water pipe ' (e-6), ' advance radiator take over ' (e-7), ' bed inner radiator ' (e-8), ' return pipe ' (e-9), ' back water pump ' (e-10), ' return pipe ' (e-11) constitute; " monitor apparatus " (C) comprise by ' temperature control instrument ' (c-1), ' temperature control sensor ' (c-2), ' bed body in oxygen gauge ' (c-3), ' oxygen sensor in the bed body ' (c-4), ' oxygen gauge in the head of a bed ' (c-5), ' oxygen sensor in the head of a bed ' (c-6), ' human body temperature monitoring form ' (c-7), ' temperature sensor for human body ' (c-8) constitute; " external respiration with mend beverage device " (G) comprise by, ' gas inhaler device ' (g-1), ' inhaler nose cup ' (g-2), ' fluid infusion input pipe ' (g-3), ' mouth inhaler ' (g-4), ' liquid supplementation pipe ' (g-5), ' oxygen input tube ' (g-6), ' liquid input tube ' (g-7), ' head of a bed oxygen supply inlet connection ' (g-8) constitute, it is characterized in that: " high temperature constant temperature hyperbaric oxygen bed " (A) is placed in " micro-wave therapeutic machine " ' degree of lip-rounding treatment head framework ' in (B), and ' degree of lip-rounding treatment head framework ' can all around move; " high temperature constant temperature hyperbaric oxygen bed " (A) (E) connected with " apparatus of oxygen supply " pipeline (D) with " hot-water supply " and (C) (G) is connected with " external respiration and benefit beverage device " with " monitor apparatus ".
2. high constant temperature hyperbaric oxygen bed microwave cancer heat preventive according to claim 1 and thermal therapeutical equipment is characterized in that: fixed ' the sealed bed body ' of the sealing that " high temperature constant temperature hyperbaric oxygen bed " (A) made by the heat-insulation and heat-preservation material (a-1) and movably ' seal the mobile head of a bed ' and (a-2) form; ' sealing the mobile head of a bed ' (a-2) internal fixation and connecting ' bed body limit slideway ' ' flexible hole pattern bed board ' (a-21) (a-5); ' flexible hole pattern bed board ' other end (a-5) through ' inlet frame ' (a-8) stretch into ' sealed bed body ' ' chute ' in (a-1) (a-31) in elastic slip; ' sealing the mobile head of a bed ' connecting under (a-2) ' head of a bed block ' (a-3), ' slideway ' (a-7), ' horizontal filler strip ' (a-18); In connecting ' head seal is isolated soft honest and clean ' (a-15), ' neck running-on ' (a-16), ' elastic cover ' (a-17); Connecting in ' sealing the mobile head of a bed ' week (a-2) by ' lamella lucida ' (a-26), ' opaque plate ' ' movable roof window ' of (a-27) making (a-23) with ' left movable window ' (a-24) and ' right movable window ' (a-25); (a-9) go up to connect ' O-ring seal ' (a-10) and be used for ' sealing the attacker ' of (a-4) being tightly connected mutually with ' sealing base ' (a-22) at ' head of a bed frame mouth '; ' sealing base ' connect in (a-4) ' hot water inlet pipe interface ' (a-11), ' return pipe interface ' (a-12), ' the antiperspirant fan gets on ' (a-13), ' the antiperspirant fan goes down ' (a-14), connecting ' trapped orbit ' (a-6) below; Connecting in ' sealing base ' above and below (a-4) transparent air-locked ' sealing of bed top is soft honest and clean ' (a-19) with ' a bed end, seal soft honest and clean ' (a-20), two connecting ' bed body left side sealed transparent plate ' (a-28), ' the right sealed transparent plate of bed body ' (a-29).
3. high constant temperature hyperbaric oxygen bed microwave cancer heat preventive according to claim 1 and thermal therapeutical equipment, it is characterized in that " the microwave tumor is killed the thermotherapy head " (B1), " microwave whole-body hyperthermia head " ' going up magnetron ' in (B2) (b-1), ' going up lowering or hoisting gear ' (b-1-1), ' going up radiation shield ' (b-1-2); ' following magnetron ' (b-2), ' following lowering or hoisting gear ' (b-2-1), ' following radiation shield ' (b-2-2), ' microwave source electric appliance box ' (b-6), ' cooling water tank ' (b-7), ' cooling water pump ' (b-8), ' magnetron cooling water inlet pipe ' (b-9), ' magnetron cools back water pipe ' (b-10), ' magnetron power source line ' (b-11), ' pump switch ' (b-12) be installed in ' degree of lip-rounding treatment head framework ' (b-13) in following ' the therapy apparatus base member case ' that is being connected (b-14) on; ' degree of lip-rounding treatment head framework ' (b-13) with following ' the therapy apparatus base member case ' that is being connected following connection the ' left and right sides slide rail ' (b-14) (b-1-4) and ' front and back slide rail ' (b-1-3) and with ' sealing base ' ' trapped orbit ' in (a-4) (a-6) form movably " the microwave tumor is killed the thermotherapy head " (B1) with " microwave whole-body hyperthermia head " (B2); And (a-3) be connected ' instrument and meter ' and ' display lamp ' at ' degree of lip-rounding treatment head framework ' and ' head of a bed block ' and installing.
4. high constant temperature hyperbaric oxygen bed microwave cancer heat preventive according to claim 1 and thermal therapeutical equipment is characterized in that: the lowering or hoisting gear of magnetron (0-5) is connected through the Luo bolt with the eyelet of ' magnetron ' connecting plate on (b-1) by ' subbase ' of ' circular waveguide output seat ' (00) of metal ' connection eyelet ' on (0-2); ' outer Luo stricture of vagina interface ' on ' circular waveguide output seat ' (00) (0-3) (0-4) connects ' upper and lower radiation shield ' through ' Luo stricture of vagina ', and warp ' connecting frame ' (0-6) with ' manual lifting device ' (B00-1) or ' Motorized lift device ' (B00-2) (B00-3) be connected with ' hydraulic lift '; ' connecting frame ' (0-6) internal fixation connecting ' magnetron ' (b-1) with ' cooling fan ' or ' water cooled magnetron ' (b-1).
8. high constant temperature hyperbaric oxygen bed microwave cancer heat preventive according to claim 1 and thermal therapeutical equipment, it is characterized in that: (e-2) (e-3) (e-1) be connected with ' electric heater ' through ' feed water valve ' by ' feed pipe ', and ' heat supply water lines ' that warp ' electric heater ' (e-1) upward connects (e-4), ' heat supply water pump ' (e-5), ' pump heat supply water pipe ' (e-6) through ' advance radiator take over ' (e-7) be connected to " high temperature constant temperature hyperbaric oxygen bed " ' bed inner radiator ' in (A) (e-8) advance the hot-water line interface, through ' bed inner radiator ' (e-8) with ' return pipe ' of the other end (e-9), ' back water pump ' (e-10), ' return pipe ' (e-11) connects, and is back to ' electric heater ' (e-1) complete hot water circuit process system of interior formation.
CNA031230679A2003-04-292003-04-29Constantly high temperature high pressure oxygen bed microwave treating device for cancer prevention and treatmentPendingCN1541628A (en)

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Cited By (13)

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CN101912669A (en)*2010-08-312010-12-15清华大学 A non-invasive radiation whole-body hyperthermia method with body surface cooling
CN1981882B (en)*2006-04-292011-02-16天津大德环境工程有限公司Equipment for treating tumor by inputting air
CN102596008A (en)*2009-07-032012-07-18瓦格纳国际股份公司System for detection and treatment of infection or inflammation
CN107261337A (en)*2017-07-192017-10-20吉彦Cancer treating instrument
CN108066081A (en)*2018-01-232018-05-25西南医科大学附属医院High pressure nurses shower
CN108095952A (en)*2018-01-232018-06-01西南医科大学附属医院Single hyperbaric oxygen chamber system
US10265114B2 (en)2009-07-032019-04-23Levi Emmerik A. DewaegenaereSystem and method for controlling the operation of a therapeutic pad
CN111049051A (en)*2019-12-182020-04-21芜湖伊莱特电气有限公司Liquid-immersed high-heat-dissipation insulating ring main unit outdoor shell
CN111358647A (en)*2020-05-282020-07-03中南大学湘雅医院Hyperbaric oxygen chamber for treating infectious diseases and using method thereof
CN111407571A (en)*2020-03-252020-07-14江汉大学Electromagnetic induction magnetic nano particle targeted thermotherapy bed
CN111494148A (en)*2020-05-222020-08-07丁振Noninvasive tumor treatment device
CN114038572A (en)*2020-10-292022-02-11株式会社甫宗Treatment system tailored for patient of cancer comprehensive immunotherapy
CN114424973A (en)*2022-01-282022-05-03新疆医科大学第三附属医院 A tumor microwave hyperthermia system

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* Cited by examiner, † Cited by third party
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CN1981882B (en)*2006-04-292011-02-16天津大德环境工程有限公司Equipment for treating tumor by inputting air
US10265114B2 (en)2009-07-032019-04-23Levi Emmerik A. DewaegenaereSystem and method for controlling the operation of a therapeutic pad
CN102596008A (en)*2009-07-032012-07-18瓦格纳国际股份公司System for detection and treatment of infection or inflammation
CN102596008B (en)*2009-07-032015-03-11瓦格纳国际股份公司System for detection and treatment of infection or inflammation
US9237853B2 (en)2009-07-032016-01-19Thermomend International Ltd.System for detection and treatment of infection or inflammation
CN101912669B (en)*2010-08-312013-05-22清华大学 A non-invasive radiation whole-body hyperthermia device with body surface cooling
CN101912669A (en)*2010-08-312010-12-15清华大学 A non-invasive radiation whole-body hyperthermia method with body surface cooling
CN107261337A (en)*2017-07-192017-10-20吉彦Cancer treating instrument
CN108066081B (en)*2018-01-232020-12-04西南医科大学附属医院 High pressure care bath device
CN108095952A (en)*2018-01-232018-06-01西南医科大学附属医院Single hyperbaric oxygen chamber system
CN108066081A (en)*2018-01-232018-05-25西南医科大学附属医院High pressure nurses shower
CN108095952B (en)*2018-01-232020-12-04西南医科大学附属医院 Single person hyperbaric oxygen chamber system
CN111049051A (en)*2019-12-182020-04-21芜湖伊莱特电气有限公司Liquid-immersed high-heat-dissipation insulating ring main unit outdoor shell
CN111407571A (en)*2020-03-252020-07-14江汉大学Electromagnetic induction magnetic nano particle targeted thermotherapy bed
CN111494148A (en)*2020-05-222020-08-07丁振Noninvasive tumor treatment device
CN111358647A (en)*2020-05-282020-07-03中南大学湘雅医院Hyperbaric oxygen chamber for treating infectious diseases and using method thereof
CN111358647B (en)*2020-05-282020-08-07中南大学湘雅医院Hyperbaric oxygen chamber for treating infectious diseases and using method thereof
CN114038572A (en)*2020-10-292022-02-11株式会社甫宗Treatment system tailored for patient of cancer comprehensive immunotherapy
CN114038572B (en)*2020-10-292022-05-31株式会社甫宗Treatment system tailored for patient of cancer comprehensive immunotherapy
CN114424973A (en)*2022-01-282022-05-03新疆医科大学第三附属医院 A tumor microwave hyperthermia system

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