CN1350470A - Self-injection device and method for its operation - Google Patents

Abstract

An injector device, and a method for its operation. For containers with an opening for an injection needle e.g. a syringe. The injector comprises a housing, a seat or a carrier arranged to hold the needle and for allowing movement thereof in relation to the housing between a rear, needle-covering, position and a forward, needle exposing position. It further comprises a penetration arrangement operable to move the needle from the rear position to the forward position, a return arrangement to move the needle in the rearward direction, and an injection arrangement to expel container content through the needle. It also comprises a control button arranged on the housing, which, through a transmission and a switch system, stepwise trigs the penetration arrangement and injection arrangement. The button is arranged to have a least a movement component perpendicular to the needle axis.

Description

Injection device and operational approach thereof

Technical field

The present invention relates to a kind of injection device, it is used to have with the injection syringe needle or is used for the container of the opening of injection needle, this container can be to have the section injection cast of the bobbin of constant vertically, the opening that is used for syringe needle is arranged on the bobbin front end, and in this bobbin, be inserted with at least one its on the optional removable wall that is connected with piston rod, the syringe that is used for this container comprises a) housing, b) be provided with and be used for holding syringe needle or container and allow them with respect to housing and the bearing or the support that between the position of exposing syringe needle of the position that covers syringe needle of back and front, move along axial direction, c) can operate and be used for making syringe needle to move to the device that thrusts of anterior locations in the position from behind, d) Ren Xuan return mechanism, can operate and be used for making at least syringe needle to move along backward direction, e) can operate and be used at least the injection device of the content by the syringe needle jetting container, and f) at least one is arranged on the control knob on the housing, can operate to be used for starting at least the operation of thrusting device and/or injection device.

Background technology of the present invention

Although be simple on principle, the injection process that is based on the injection cast device that has injection needle still needs to be grasped several separate steps.Before pure injection process, need some start-up operations.May need according to the correct dose that will distribute and will charge into syringe from preserving the medicine that container for example extracts the liquid medicine bottle.In order in the disposition of reality, to avoid this step, generally provide the syringe that is pre-charged with, but in this case, may need the step of a dosage setting or selection.In moving its first time, the syringe piston can need one to shake off power especially after storage, overcome the inner resistance that is shaped again and owing in the adhesion of contact point or lack lubricate cause become big wall friction power gradually.For the consideration of storing or preserving effect duration, pre-syringe of filling is paid with the form of two or more chambers sometimes, thereby and then needs extra blend step before handling.Deaeration step and the step of spraying in advance are normally necessary, removing the gas in container chamber, and fill up the space at the place, inside of for example pro-sealing place, outlet adnexa place and outlet device or syringe needle.Definite says that injection process relates to following basic step, comprising: thrust skin with syringe needle, carry out the injection of medical formulation, extract syringe needle out from tissue.Being organized in of injecting is for example subcutaneous, intramuscular, sponge is intravital or intravenous injection in may be different, therefore need slightly different injection techniques, comprise drawing step.General situation is that whole syringe needle is thrust in the desired destination organization, only injects after the correct location of syringe needle, and before extracting syringe needle out the dosage of regulation is all injected.After injection, generally to seal up for safekeeping or damage, to avoid propagating infection because of neglectful secondary syringe needle thrusts to major general's syringe needle.

Also can satisfy these needs when then using for example common hypodermic tube of the simplest injection device when being used by experienced operator, this operator also can be in the relevant adjustment measure of carrying out under the situation of accident or fault in the medical treatment.But the general tendency of handling is to give patient oneself with the responsibility of administration, comprises child, adult and people with disability.In secular processing, patient can grasp certain skill usually, but also can have the administration situation of seldom using, and generally includes the situation of urgent or patient's disorder.Compare with the administration of nurse operation, other the unique problem that occurs in patient's automedication is need position more inappropriate and that normally be out of shape, and the action pattern of medical coideal to be disturbed in the painful or uncomfortable meeting of recognizing or live through.In a word, automedication especially needs more perfect device, avoids so that injection process is easier or reduces the danger that makes mistakes.The patient who depends on every day or irregularly administration requires reasonable need easily in addition, and installs and should enough disperse, to use in daily life.And also wish this improve and facility is simple and cheap, can be extensive use of and comprise disposable apparatus.

Existing for a long time more or less is automatic device, so that the layman of the limited training of process can have the injection of suitable safety under crucial or urgent situation, perhaps the patient for frightened syringe needle inserting step provides a kind of selection.On common automatic injector, be provided with mechanical automaton.Usually user wishes with correct injection orientation this device to be pressed against on the skin, operates a trigger button then.The mechanical energy of for example being stored in spring system can thrust automatically that tissue, medicine are injected automatically or also may carry out drawing back automatically of syringe needle then.Better simply device may not thrust device automatically, inserts but the hypothesis user can carry out syringe needle.Usually, in case after triggering, no matter do it on purpose or be not in the mood for, this operation sequence all can irreversibly be carried out.Because related spring-back effect is changed with being forced to, particularly, the power that is discharged sets, in addition so the risk that misplaces in machinery generally is high owing to may being necessary at the operation resistance of predictable maximum.Except expensive and ugly, these devices almost can not provide experience that injecting program controls fully and cancel in pain or when uncomfortable or the probability of calibration injection program for patient.

Automaton based on electronics or electromechanical principle was also once proposed.These known devices have been utilized the advantage of automatic principle aspect several, for example utilize motor accurately and duplicate injection, motor auxiliary thrust automatically and mix or reconstitute, the setting of identification, sample analysis, injection data collection and the processing of cartridge case, dosage, syringe with respect to the orientation of gravity with correct mixing or degasification etc.Certainly this various probability makes this automaton be applicable to many situations, is particularly useful for repetition or often use, but this device is too expensive for extensive or disposable application.In addition, for the patient who likes individual's operation, function may be bad automatically.

On the contrary, better simply Prosthesis may can not provide above-mentioned human engineering, easily or security needs.For example injecting the cast device thrusts step or extracts out and can or seldom not offer help aspect the step at setting up procedure, syringe needle, and the heavy reverse handle of needs, be used on many body parts, injecting, and can not provide safe order for each related step.Proposed and sold many so-called " injection pen ", be mainly used in multiple and regular automedication, for example insulin or growth hormone have inserted the syringe and medicine bottle of multiple dosage in this device, and throw in the dosage of selecting in advance, this is generally undertaken by handling the end button.It is more convenient that this device is designed to make use every day, and help dosed administration repeatedly, but can not solve about hypodermic other problem.Another known injection device be its control knob can positioned alternate so that the injection device of injecting.For example patent description US4444560,4581022 with 4820287 and WO96/17640 also disclosed the transverse bar that has the connecting device that is connected with piston rod, mainly be the extrusion pressure that is used to amplify stringing toothpaste.The gun type handle that has connecting device that is used to inject also is known, and for example FR2717697 is mainly used in and conveniently catches the instrument that is used for a large amount of injections of veterinary.Can know from FR2586192 that in addition but the fine setting that horizontal unlocking wheel is used for syringe needle mechanism moves, be mainly used in laboratory work.These all solutions are not used for automedication, are not optimized for this purpose yet.For example the neither one solution is used for the controlled mobile of syringe needle and injection mechanism.It is known having the simple mechanism that is used for syringe needle and injects the parts that move, US5425722 and 5147323 for example, but do not consider automedication equally, for example be used for the different handle of two operations and do not guarantee correct sequencing by needs.

Therefore need a kind of simple and cheap injection device always, it can help user in involved different treatment step, thereby prevent or avoid mistake, and provide ergonomic, easily with atraumatic product, be particularly useful for being in the patient of automedication situation.Although the present invention also can have more general purposes, it mainly is described at above-mentioned background.

Summary of the invention

Main purpose of the present invention is to avoid the shortcoming of above-mentioned known injection device.Purpose is to provide a kind of injection device more specifically, and it can carry out, and syringe needle thrusts and injecting step, also can carry out syringe needle and extract step out.Another purpose is to provide a kind of device that manual capacity regulator is operated that mainly depends on.Also have a purpose to be to provide a kind of device that can help to carry out injecting program at setting up procedure.Also have a purpose to be to assist in ensuring that correct injection sequence.Also have a purpose to be to provide a kind of device that be exaggerated or controlled power can be provided in each operational phase.Also have a purpose to be to provide a kind of device of throwing in various dosage that is applicable to.Another purpose is to provide a kind of device compatible mutually with the pre-filling injection pipe of various characteristics.Also have a purpose to be to provide a kind of device that is used for automedication.Also having a purpose to be to provide a kind of in use is device ergonomic and that be convenient to operate.Also have a purpose to be to provide pain and uncomfortable can minimizedly device the in a kind of feasible use.Also have a purpose to be to provide a kind of device that is provided at the control on the injection process for the user, keep safety simultaneously.Also have a purpose to be to provide a kind of simple mechanism cheaply, can be used as a kind of disposable apparatus.Also has the method that purpose is to be provided for operating said apparatus.

These purposes of the present invention are to realize by the apparatus and method that have in the feature described in the appending claims.

By using the control knob that can externally touch that is connected with this equipment mechanism, whole Machine Design can be simple and cheap, and wherein said connected mode makes it possible to utilize the manual force that is applied on the button to carry out the operation in each stage.What make mechanism in each stage is moved into partial function at least into button positions to small part, then from the operation of being taked for patient provides feedback, thereby can carry out corrective action.If for example syringe needle thrusts skin and produced pain, then can carrying out slowly, syringe needle inserts, a new target site is operated or selected in cancellation.Equally, if experience pain at injection stage, then injection speed can be lowered, cancel or intermittently carry out.If it is reversibly relevant with the position of control knob that the stage moves, then uncomfortable cause also just can reverse fully, for example makes that part or all of syringe needle can bounce back in the stage of thrusting, so that proofread and correct or postpone injection process.In injection stage, oppositely can make and for example in intravenous injection, aspirate.Use identical control knob to make user to carry out all these stages and need not change handle for thrusting step and injecting step, and allow only to use a hands, reduced because of the replacing of handle dislocation or vibration cause the danger of pain, and eliminated by wrong control element be not in the mood for operate or two times of multiple control start the cause that forms incorrect precedence.These advantages and repeated use and the operation that is used for the same control knob in each stage are consistent.This in addition layout also is used for providing from the carrying out in stage and the tactile feedback of completion status to patient, has increased patient's control force thus, and has reduced risk of errors.It is easy to mechanical transition between the stage in addition, and can carry out the function adjustment to the needs in each stage, for example different gear ratio between the permission stage or the response characteristic of change in a stage.It also makes and is used for the simple and mechanical locking of or irreversible step enforceable in program chain or the layout of releasing parts becomes easy.Enforceable treatment step replenishes as the step that controlled by patient, it is used for auxiliary user and avoids dangerous precedence mistake, and guarantee that a stage is correctly finished before carrying out in the next stage, also be used for not making it be trained and can be accustomed to this by will having empirical user to guide to desired injecting program.Have been found that the design control knob is favourable, in particular for the automedication purpose, thereby when operating at least partially in vertical direction rather than in coaxial mode, control knob is moved, and preferred side or the lateral attitude that utilizes with respect to device case with respect to needle axis.Control knob not only can be by finger, also can push and touch by palm, utilize one or two hands can carry out more stable startup, and produced the advantage of the general importance of eliminate pain, and user can reduce the strength of hands or the advantage of ambulant particular importance.This device can be maintained in the palm in addition, needle forward or all equivalences backward, and the scope of extended operation like this, and make this device makes to be used for saying to be effective on an equal basis for patient and nurse.When this device was pressed towards skin, control knob had reduced any triggering danger of not being in the mood for the stage that is used for beamhouse operation with different mobile of thorn Inbound.For the length of given syringe and medicine bottle, this layout also allows to be used for the shorter and more portable device of integral body.Above-mentioned general design principle with do not fill or the common list of pre-filling forms or multi-cavity chamber syringe and medicine bottle type and their needed initial steps are compatible fully.If desired, this device can comprise the device of setting dosage by simple limited piston length of stroke.Can easily realize being used to improve the needle retractable ability of injection back degree of safety for the minor modifications of thrusting mechanism.All device characteristics are realized by low-cost parts, make it can be used for most of medical applications, comprise disposable disposal type application.

Other purpose of the present invention and advantage can be clearer from following detailed description.Describe in detail

When not having opposite special instruction, used here expression way for example " comprises ", " comprising ", " having ", " having " and similarly term should not be understood that restriction to the exclusiveness of described element, but should be understood that to allow other parts to exist, and should be understood that to contain the element of the form of any integral body, segmentation or set.Equally, as " connection ", " adhering to ", " setting ", " applying ", " between " and similarly term should not be understood that the direct contact between the element as described in the special expression, but should be understood that to allow to exist one or several insertion element or structure.This equally also is applicable to the similar expression way that is used to explanation of force and does the time spent.

Also have power in used and the control that is applied to device or the relevant notion " manually " of energy should be understood that to refer to operator here and apply power or energy in the mode of this process of control under consideration directly or indirectly.It should be understood that, though servo auxiliary device normally unnecessary or be not preferred, but also comprise servomechanism installation, in these servomechanism installations, as long as operator's action has determined process, then just helped the driving of this process by all or part of usefulness from the power of the energy beyond the operator or energy, the energy for example in spring or gas or the energy that provided, stored.Move with " triggerings " that can be ON/OFF action and to compare, manual activity at least in part or on the limited scope with the program that is being acted in the position become a kind of functional relationship.

Described here syringe can be used among the medical field and outside multiple use, and in any vessel the preparation of any type, for example chemicals, compositions or mixture, and can be used for carrying for purpose arbitrarily.Owing to described reason, this system has some special value in the medical science conveyer device, and design constraint is also than stricter in other purposes of great majority in these devices.For convenience's sake, the present invention will be described according to this purposes.

Usually the material that will carry is a kind of fluid, and preferably a kind of liquid, comprises the material of its performance as liquid, for example emulsion or suspension.These observations relate to final preparation, and other composition especially solid may before final preparation, just exist.The characteristic of container contents also should be understood to include sensu lato medicine, though and the most generally this medicine be factory preparation, this content also can be contained for example to be advanced by preliminary filling or be drawn into natural component and body fluid in this container.

The container that can be used in the present syringe generally includes the container that is used to prepare and can therefrom import the opening of formulation, and can adopt the Container Type of wide region.All here be called as " syringe needle " thus syringe needle, intubate or similarly penetrating device should be by for example being located on this opening or being located on this opening and described opening fluid communication by conduit.Unless container itself has the device that is used to inject its content, otherwise just need pumping mechanism in addition, this will be further described.The container of injector type preferably is used in the conventional injector, and should understand in a broad sense, and can be said to be usually is to comprise a bobbin, this bobbin has the previous section and the aft section that define a general axis, be located at the outlet of formulation that is used for comprising usually a kind of sensu lato liquid of front face office, and at least one removable wall that is located at the rear face office, the mobile of described wall makes described formulation move or be pushed out by outlet to outlet, therefore comprises a kind of inherent pumping mechanism.Tube-shaped must coadaptation mutually with removable wall.For example its inner section of glass or plastic bobbin can be substantially invariable, and have same constant bobbin axis between the front and back part that is substantially tubular bobbin providing, and most preferably this section is to provide to be the general circle of cylindrical barrel substantially.Thereby removable wall is preferably and is essentially solid shape, though it can be with the inner bobbin face seal the elastomer that adapts, be preferably piston type.Front end place at bobbin is provided with syringe needle, and the present invention adopts preferably wherein that needle axis is arranged essentially parallel to the bobbin axis and most preferably is concentric with it container, thereby causes thrusting with injection movement substantially parallel.In these restrictions and the range of choice, for conventional injector, can adopt the injector type of wide region, for example syringe and medicine bottle, cartridge case, carpoule and syringe.This container needn't have independent piston rod, though this container can have a piston rod fully, i.e. parts that stretch out from the bobbin tail end, injection mechanism can act on this piston rod so that make the piston motion, but preferably this injector mechanism can more or less directly act on the removable wall of container, because many standardized devices all are designs like this.This syringe can with for example in DIN and iso standard the volumetric standard type of defined use.Can also adopt the container of two or more chamber types, for example known being used to requires to mix two or more the component or the preparation of precursor before administration.These components keep separating by the one or more midfeathers with different known design, these walls are divided into several chambers with this bobbin, these chambers are arranged in parallel along cartridge axis sometimes, but in most cases become stacked relation along this axis.Can these each compositions be lumped together by the valve arrangement of breaking, penetrating or open in the midfeather.In another kind of known design scheme, midfeather is a piston type, and the fluid flow between chamber is realized by piston being moved to bypass part, in this by-pass portion office, inwall has one or several amplifier section or multiple annular groove and platform or piston distressed structure, and its mode makes that the chamber contents of back can be along with the displacement of the removable wall of back and flow to the front chamber from the side.These chambers can air inclusion, liquid or solid.Usually there is a kind of liquid at least.Modal in the purposes of making up a prescription is to have only two chambers, and comprises a kind of liquid and a kind of solid usually, and the latter is dissolved and reformulation during married operation.Container for these types, when container is placed in the syringe, mix or reformulate step and may all finish, perhaps might in this device, be provided with the parts that the content that is used for making these chambers before beginning the actual injection process becomes one.

For the position of syringe needle, container and syringe and the explanation of direction, for example " axial ", " front " and " back " should be understood that with the syringe needle to be reference, though be configured to equally as described when mobile together when syringe needle and container for the injector type container, the above-mentioned parts that are used to refer to container also are the same.

Syringe needle can be connected this container front in any way, for example undertaken by known ways such as gluing, weldings for good and all fixing, the perhaps known manner by for example luer connection of a kind of installation method, screw thread, threaded spline, snap on system connection or their combination.The container front should match with selected installation method type, for example for fusible material, be added with and can be penetrated or disruptive barrier film or have the valve or the by-pass collar of front.Obviously most convenient is that syringe needle can be connected by manufacturer before injection, also can be connected by user, for example guarantees that user keeps aseptic, allows to select syringe needle type or metering numerical value maybe can reuse this device.Also have according to general custom and can syringe needle be covered with a kind of aseptic needle shield of keeping that before using, can be removed immediately.Preferred employing standard needle, syringe front end and installation method are so that keep low-cost.But can improve to obtain special advantage.As in the device of above-mentioned US5425722 and 5147323, syringe needle needn't directly or rigidly be installed on the container, but can be with any other fluid connected mode.For example in order to allow syringe needle can be independent of that immovable container moves in housing, and the motion that in the step of for example thrusting with needle retractable, suitably limits syringe needle, this can simplify the mechanism of this device.Unless otherwise noted, this selection scheme should be considered to be included in the movable support or support notion that will describe.In this case, container needn't be the syringe type, but can adopt any vessel type, and passes through any based on suction from container, the pump machanism that is injection, peristaltic action etc. is then injected, and for example container is pushed, forward moves for example piston/cylinder type of pump.

Injection device comprises housing, and this housing should be understood in a broad sense, and mainly as the reference position that is used for the explanation of other parts and position component and direction.But preferably this housing is in fact also wrapping these mechanisms of this device at least, and mainly allowing those be come out by the component exposed that user touches, mainly is that control knob also has for example dosage setting, siren, supply of accessory, triggers and hold up control.Container can be installed on the housing in this mode that still keeps exposing, but preferably housing is also fettering container, preferably also has syringe needle, is activated up to thrusting.This housing can be designed to partly or can open fully and/or can close to touch or to close its inside, this can realize by any known separation or openable device, for example may have the threaded or hinged parts of reversible or irreversible locking device.Reversible locking can be used for touching the inside of device so that for example regulate or control or be used for allowing simply inserting or changing container, for example allows to reuse this device so that pack selected formulation type or dosage or change formulation type or dosage into.The same as noted, usually preferably this device is used as and can disposablely uses, in this case, preferably it is loaded onto with container, and the simple sealed device has very big meaning for the reasonable assembling in making in factory.Because insurance and security reason, irreversible sealing is to preventing to damage employed container and syringe needle is effective.Say that in a broad sense hull shape is unimportant for the basic function of this device, but can influence its man-machine control and characteristic easily.The global shape of housing can be arranged according to inner member especially and take different shape.The same as noted, this housing includes container and the drive mechanism between control knob and container at least.As in the prior art, most of mechanism components can be arranged on the back of container in the axial direction, and the housing that is minimized in this case can be taked a kind of elongated form.Control knob can be designed to axially push.Because described several reasons, preferably control knob is designed to laterally move relative to container axis, and select for this, preferably at least control knob be positioned at container axis to the small part side, preferably between container end portion, and preferably to this mechanism of small part equally between control knob and container.Thereby the housing that is minimized that comprises these parts forms axially short but the shape of horizontal broad, if and the horizontal expansion of described housing except button partly is taken as " highly ", then extending axially part is taken as " length " and is taken as " width " perpendicular to the size of these two parts, preferably the ratio of maximum height and Breadth Maximum is preferably greater than 1.5 also most preferably greater than 2 greater than 1.The ratio of greatest length and maximum height generally remains less than 4, preferably less than 3 and most preferably less than 2.5.Described global shape is found and can meets human engineering, structurally is inflexible and is easy to operate in the mill and assemble.

This syringe also comprises needle holder, its minimum requirements is to allow syringe needle (when connecting rigidly preferably syringe needle and container) axially move so that thrust between position and the anterior locations in the back with respect to housing at least, and the motion between those positions is used for thrusting.The distance of being moved between these positions should be at least corresponding to the desired degree of depth of thrusting, and is hidden in the enclosure interior when syringe needle before thrusting step, also corresponding to carrying out internal motion to expose the needed distance in syringe needle end.Needle holder can comprise with respect to the fixed guide frame of housing, thereby fixed desired syringe needle passage, perhaps selectively or in addition can comprise the support that can move with respect to housing, and syringe needle or container are fixed in this support.According to the design of selected needle holder, described thrust mechanism can thrust or needle retractable during act on directly or indirectly on syringe needle, container or the support so that promote syringe needle.Optional is, the actual degree of depth of thrusting is in bearing passage for example or to thrust in the mechanism be adjustable.Perhaps regulate this degree of depth by selected needle length.

As described, this device should include at least and be used for the device that syringe needle thrusts the injection movement of motion and container contents.Preferably this device also comprises the device that is used for needle retractable.Further preferably be included in the parts that help user in the injection setting up procedure that to describe.

Have some similar parts with the respective performances in the automatic injector, for example in simple device or in order to have a mind to carry out the dispersion injection of entire depth, thrust and inject and to carry out simultaneously.Usually require the restriction injection to arrive or near its target location up to syringe needle.This function can realize with the force system that is used for two kinds of purposes by acting on removable wall or the piston rod, this be because under normal circumstances since the sequencing syringe needle to thrust resistance ratios fluid injection flow resistance lower.But during thrusting, still be difficult to avoid at least some to leak, and especially in thrusting the situation that motion is prevented from or blocks, injection will fall flat, thereby be injected at formulation on the skin or at incorrect degree of depth place.Therefore the power of preferably will thrusting is applied on syringe needle or the container directly or indirectly, and this just needs some controlling organizations, is used for thrusting in major part stopping to apply injection force in the phase process and only can applying injection force after correctly thrusting.The needle retractable step can be carried out the artificially, but preferably be semi-automatically to carry out at least so that guarantee to make needle safety to hide, this can realize in a kind of known mode, wherein syringe is pushed back after being used for finishing injection in the syringe thrusting the stored energy that is stored between moving period in the more weak answer balancing spring usually.Also have, this function needs a kind of controlling organization, only be used for after finishing injection, just making returning spring to act on, thereby this generally is to remove to thrust from injection tube by the specific end forward at piston or piston rod with injection force returning spring can freely to be moved to realize.

Thrusting motion should be undertaken by the ARTIFICIAL FORCE that employing is applied on the control knob, and need a kind of transmission parts conveying capacity between control knob and syringe needle that thrusts, perhaps can be by means of container or support, at that rate, for above-mentioned reasons, preferably by means of the container bobbin.Can adopt arbitrarily common actuating device in principle, for example dynamo-electric as electric notor or solenoid, system such as hydraulic, air operated, but in order to simplify preferred employing machinery.Can adopt various ways according to button positions and this transmission of activeness.If for example button is placed on the housing in the axis extension office of container or needle axis, if then the activity of button is towards the front then this driving member can be a kind of more or less some inflexible connector, if this button is configured to rotate then this driving member is screw rod and nut driving member around described axis.Preferably this button setting is used for moving, and have parts at least perpendicular to needle axis, most preferably when moving, housing is used for needle injection at button, for example along the converting motion that more or less is directed to of such button passage or around the pivot center pivot center of housing width (preferably along) when rotating, the pushing zone of button can be positioned at the pivot center back in this case, but preferably in its front.As described, thereby this button most preferably is arranged on the side of needle axis still between the container end portion border.In these situations, a kind of driving member that can make the power reorientation that is applied on the button of preferred employing, this can finish with any known this actuating device, for example line or belt formula device, connecting device such as the wing and adapter system, leverage and be preferably wheel, be preferably toothed wheel, the motion of button makes wheel turns so that advance syringe needle in this system, preferably by means of rack rails.If requirement, then any driving member can comprise the force transformation parts to increase, to reduce or change power in thrusting stroke.Can adopt known this device, for example by adopting gear ratio, degree of leverage, elbow or adopting cam face.Also have control knob self can be used as leverage,, and bounce back and put so that transmission by making pressure spot be adapted to power for example if hinged.In general,, only need less power, and in order to obtain good patient's control and feedback, preferably the button haul distance can be too not short in this step so thrust step because the insertion resistance in soft tissue is very little.Preferably, the ratio of finger motion on button and syringe needle movement length is greater than 0.1, is preferably greater than 0.2 and most preferably greater than 0.5.Preferably this ratio is less than 10, preferably less than 5 and most preferably less than 1.It is desirable to, for example provide certain stop for the button motion when the whole predetermined needle injection by stop surfaces is set on the optional position in the chain between button and syringe needle.

Injection movement can its role is to reduce the number of steps of being undertaken by patient thrusting between moving period or automatically carrying out afterwards, perhaps for example because the cause of the component of stimulation in injected formulation and when injection pain is inevitable.If adopt such power to apply principle, wherein under the effect of the continued operation of control knob, the power of thrusting is applied on the removable wall of described container, so just can obtain this result.Perhaps can for example non-manual stored energy be applied on the injection mechanism by spring or baric systerm, this is stored energy and preferably is released when thrusting the motion end, this moment its need one with automatic injector in the similar actuating mechanism of mechanism, a mechanism on housing for example is used in housing untiing the energy drives part stored and the locking between the removable wall corresponding to finishing the position of thrusting.For the above-mentioned reason of mentioning, preferably injection movement also can be undertaken by utilizing manual capacity regulator, because wish in injection, may produce pain or uncomfortable feedback and the control that especially when a large amount of injection, is provided for corrective measure, speed controlling perhaps be provided to injecting from injection to patient.After the control knob that use is used to thrust, can carry out this manual injection by using independent injection to control, can use any known injection mechanism or described actuating device for this reason.But preferred use also is used for the control knob of injecting program.Thereby between control knob and the removable wall of container, need an actuating device, and be similar to the device that is used to thrust, but it acting on the removable wall, above-mentioned any transmission principle also can be used for injection.Can use a fully independently actuating device that is used to inject, but preferably this actuating device comprises the common unit that is used for two kinds of purposes, most preferably, they are basic only in needs part difference, particularly at the parts that are used for switching between the stage with to aspect the adjustment in each stage.The latter's interesting part may be the requirement of adaptive faculty, because it is higher to be compared to the requirement of thrusting for the requirement of these power of injection.This can accomplish by improving gear or lever ratio.Preferably, the finger mobile phase of ratio move for syringe needle greater than to(for) the ratio of the movable length of removable wall of the finger mobile phase on the button in the fashionable use of thorn.For injection, described ratio is preferably greater than 0.2, is preferably greater than 0.5, most preferably greater than 1.Preferably this ratio is less than 20, preferably less than 10, most preferably less than 5.When the mobile trend of finger is the length of inconvenience, can and preferably allow the repetitive operation control knob, be emptied completely until container.

For the single option of operation of above-mentioned tube, when for example on acting on the removable wall of container and to two stages, all using single button stroke, can comprise that any switched system starts respectively and stops, or redirect the power that is applied on the control knob.But, preferably include a this switched system in order to realize most of above-mentioned preferred ability.First kind of desired switching function is a stage switched system, thereby make applied force can be at first directly or indirectly for example act on the syringe needle to thrust, act on directly or indirectly then on the removable wall to inject by container bobbin or support.Second kind of desired switching function is to reconnect system, allows control knob to carry out repeatable operation.These required functions are complementary to a certain extent, for example on button push or the effect of unclamping for example can be used to move to a specific location implementation phase at button and switches, but preferably use other parts outside the button, these all probabilities and combination can not be by itemizings.In a broad sense, the stage switch can be preferably between syringe needle and housing certain position to axial carry out, for example corresponding to thrusting the place that stroke has been finished, or preferably a little in its front, to avoid the too high tolerance on switching mechanism.In fact, switching can preferably be finished by the structure that has the basic fixed position with respect to housing, to redirect or to untie the power that is used on the removable wall that is used for that is applied, for example by deflection, rotation or other mechanism, or preferably by preferably applying power by wheel at the constant position place, wherein automatically switch when mobile finishing to thrust, for example by making wheel at first act on the surface that is used to thrust, change to the surface that is used to inject when finishing when thrusting then, this principle also allows to be used to change gear ratio.For some reason, for example in order to ensure correct sequencing and avoid careless extraction, for convenience later syringe needle is drawn back and adjusted and finish etc. in order to show to user to thrust, preferably provide a locking member syringe needle at least temporarily to be remained on the position of front, this can be realized by any bolt lock structure, for example hook formation preferably is deflected to be engaged on automatically in this position, perhaps is designed to or provides confirm thrusting sense of touch or the audition finished.This breech lock can be permanent, if for example there is not syringe needle to return function, or utilize the parts of internal structure and knock-down, perhaps if be used for syringe needle or container prepass, it in addition can be manual.

The stage switched system of aforesaid suitable design preferably utilizes other structure outside the button, thereby brings very big design freedom can for the mobile form that reconnects system and control knob.Can use a button stroke for thrusting and injecting, for example be used for making patient's work to minimize, or be used for injection in a small amount or thrust the degree of depth, or allow the sucking-off of liquid, and not need to reconnect system in this case.Wherein for relevant feedback of stage is provided to patient, be used for the layout of relevant adjustment of stage or avoid long button stroke, preferably on button, use at least two active forces, preferred at least one be used to thrust and at least one is used for injection, in a stage, several strokes can be arranged, especially described injection stage.This can for example be used to carry out the stage switching by the decline of using the first button stroke by button is realized as part stage switched system, utilizes being moved further of button to inject then.But preferably, use above-mentioned stage system principle rather than button, its allows connected system is again carried out more common design.The common system that reconnects allows two-way button motion.It can allow power to be applied to actuating device in the motion of both direction, but preferably is configured to a direction of motion to be idle, preferably to dally that this is a most convenient when moving away housing.Mechanically can use any known unidirectional or two-way parts, clutch for example, based on the mechanism of centrifugal force or frictional force, ratchet and ratch mechanism or preferably have the wheel of removable axle.Utilize so any design, button motion can freely repeat, and for example allow patient's mistake or neglectful action, and the stage switched system is guaranteed correct stage sequencing.Reversible stage effect is possible.For example the motion of the syringe needle in the process of thrusting can reverse under certain situation, this is favourable, if for example feel that pain just allows to interrupt or select new injection site, perhaps allow syringe needle or container front end to expose so that check or carry out syringe needle and install.Reversible thrusting can capablely obtain along syringe needle inverse direction bias voltage by for example making, for example by a needle retractable spring.In injection process, utilize the common system that reconnects to realize several stroke pump action usefulness automatically, although if moving backward of container has been prevented from, for example in utilizing the embodiment of fixed container, if there is not bias voltage backward, or be locked in top position as mentioned above, so safer.In injection process as an other safety measure, especially when the several stroke of needs, can prevent moving backward of removable wall, for example by only allowing to act on moving forward of part on the removable wall, for example by comprising friction element, a unidirectional ratch mechanism or passing through similar means.Further preferably make button self towards one of its position and bias voltage, preferably towards the button starting position, the outer terminal position of housing relatively for example, this can by simple and cheap parts for example the spring of metal, elastomer or plastics realize.

For the reasons mentioned above, in this injection device, preferably include syringe needle and return function.For being used for the needle retractable applied force, adopt and thrust similar idea, promptly power can directly be applied on syringe needle or its adnexa, is applied on any support of container bobbin or these parts.Syringe needle can bounce back by applying manual force, thereby for example also provides control for this effect to user.Thereby an independent control piece can be set, allow simple structure and simply connection between control piece and syringe needle.For convenience's sake, preferably needle retractable is also used control knob, particularly can carry out with injecting program associated ground and be used for from organizing under the situation about drawing back in this step.Thereby need a principle and thrust and inject similar transmission and button reconnects system.Extracting syringe needle out from tissue is not the work of a misery, but it needs Artificial Control completely.For this reason with for other reason, preferably make syringe needle at least partly automatically withdraw.This function can be automanual in a sense, promptly after forcing manual triggers, the needle retractable process is automatically carried out, preferably by discharging the energy of storage, a known way that is used for the return spring that syringe needle moves backward for example is set carries out, wherein said spring thrusts in the process at syringe needle usually and is compressed.Triggering can be carried out by means of an independent control piece that is provided with for this purpose, but preferably this control knob also as the trigger of needle retractable.This control knob can release needle bounce back when it is released after injection, but the other multiple push-botton operation of preferred employing.For the easiness of the highest safety and operation, needle retractable can be that the specified point place of this step in injection process carries out, and do not need user to carry out any manual triggers fully automatically in a sense.The point of this process preferably discharge to finish and the time marquis that finishes of injection stage thus at formulation, this can be to be emptied completely marquis when removable wall is reduced to minimum point under the situation at container, also can be under the partially draining situation in certain removable wall position, the latter is mainly used in dosage and can is set or adjusts or be used for from multi-dose container reinjected the time.In other words, the removable wall in arrival precalculated position is used as the trigger event of needle retractable.Any parts that mechanically comprise the injection actuating device of button can be as internal trigger, and wherein these parts and removable wall position have the certain location relation, as discharging the energy of being stored by opening the return spring breech lock.Be provided with under the situation that breech lock keeps the position of syringe needle after thrusting, with aforesaid optimal way, preferably this lock can be used to start the return spring effect.After needle retractable, need forever to discard under the situation of this device, for example for disposable apparatus, a device can be set to be come in non-removable mode with on any position of needle locking in advanced position and in driving-chain, for example by any known parts.As the part of this feature, or additional, for example come to show user mode that this control knob can be locked and prevent from further to move, and preferably moves to shelf space in its compressed position to user.Do not having the needle retractable function, but depending in the situation that other safety prevention measure for example destroys by fire, for breaking-up, after injection stage, can carry out nondetachable locking.

In order to allow to set the dosage that will be ejected, for example, can comprise dosing mechanism for part or multiple injection.Since dosage setting generally be before the actual injection program is activated, carry out and on setting position without any restriction, so can be provided with the degree of freedom bigger for the control assembly of this purpose than control knob.Although can comprise the adjustable mobile limited part that acts on the removable wall equally, the limited part on the parts of the general preferred front that is provided for acting on the injection chain.They can be arranged in the control knob or be arranged on any position of injection transmission, but independent this limited part preferably is provided.Can use any common parts, known to for example in injection pen.If influence the decline of the actuating device of removable wall or piston rod be taken as be " jumper bar " device, then for example can use an adjustable surface that stops being used for the jumper bar device, adjustable space is used for respect to removable wall and jumper bar or its combination out of service.Being used for the injection stroke length of button or the length of stroke of combination can change because of different dosage settings, constant but preferably selected its length of stroke of dosing mechanism is retained as, and irrelevant with dosage setting.

Further preferably, in device, include the parts that are beneficial to the setting up procedure before the actual injection.Can supply the device that does not have any container or syringe needle, subsequently these parts be installed, install for convenience, the container place can comprise installed part, for example pushes lock, bayonet, screw element or any other assembly parts.Syringe needle can be installed on the container in advance, but it needs and then to install before using usually, or allow to replace, in most of the cases, before using, need to remove needle shield, in these all situations, syringe needle installation site (the most normally container front end) is must be palp for the user.Perhaps this device can have the part of a storage of needle before installing.Under the situation of two or more chambers, the startup of tube needs the startup of removable wall to move, so that all even mixing of material in the chamber, although this step can be carried out before container is mounted to device, but preferably when being connected to device, carry out, for example allow the jumper bar device initially to move relative to removable wall, for example by from actuating device, temporarily unclamping, but preferably by making container axially can move with respect to immobilized jumper bar in housing, most preferably be to allow removable wall to move carefully, described in US4968299 by being threaded.The startup campaign of removable wall also must be carried out degasification and pilot injection, and this motion can utilize as carrying out with parts the container class of a plurality of chambers.Any startup campaign of removable wall needs the high power of shaking off.For any or all these effects, at least the front end of container is that palp this point is favourable for user, it can be set for by utilization and thrust mechanism and the small part that arrives is thrust motion, and preferably temporarily locks this position and stop the maneuvering sequence that is applied.Also can and usually preferably make at least the previous section of device open or can open by removing hinged door etc.The displacement that is used for the removable wall of above-mentioned startup purpose can be by manually pushing jumper bar or container to realize each other to along axial direction.But helpful leverage or gear ratio preferably are set, for example are used for improving the power that is used to shake off, reduce blended speed or make the startup motion shorter on degasification and pilot injection.Can use any known leverage principle, but a preferred device is to use hinged door for the device front, it is closed and makes container move backward, preferably under the effect that moves forward under the effect that power is amplified and preferably, for example when this wall when being immobilized substantially with respect to housing at removable wall.After door is closed, this syringe needle preferably is hidden in the housing, and preferably this door is arranged to: unless syringe needle is correctly connected, otherwise it can not be fully closed at least, and this door for good and all and is irreversibly locked, and perhaps also can be configured to stop any further variation of dosage setting control (if any).Door can also be used to influence possible control knob and move, and particularly starts or stops it and move.For example this button can be inoperable, is fully closed until door, and utilizes above-mentioned any additional function, perhaps is connected by breaking away from actuating device, or keeps static by the blockade of button or actuating device at given position.These all devices are used to guarantee correct action sequencing, and reduce risk wrong or that mistake is used.

The using method of this device is to draw from the description that is made of structure, function and purpose.Be the general introduction of preferred effect below.Remove or open any door and cover plate on this device front.If this container is not to be assembled in advance in the device case, the operator inserts container so, perhaps it is connected on the installed part that is provided.If container is two or more chamber device, married operation can carry out before being connected to device so, but preferably when connecting or be connected in the process of device and carry out, preferably by relate to container towards remain static lean against jumper bar device on the removable wall and axial displacement be used for carry out.Unless syringe needle is in place, otherwise the operator will be installed to syringe needle on its bearing, perhaps removes the needle shield of any existence.This syringe needle is roughly made progress, and removable wall is moved forward with discharge gas, and can spray formulation in a small amount to confirm to have correct function.Preferably this wall is moved forward, and container is moved backward by container is moved backward with respect to the jumper bar device.This moving can be handled with lever, thereby the length of closing can surpass the container shift length.Preferably, this is closed and also is used for making control knob to act on.The step of being carried out confirm that syringe needle ensconces in the device now.If suitable, dosage setting operation so up to the present can be carried out at any time.Control knob can be operated to be used for thrusting and move syringe needle is delivered to the position of exposure.This preferably finishes in single step, and need not repetitive operation on button, and is preferably undertaken by button being pressed to housing, moves preferably to have at least one component perpendicular to axial direction.The syringe needle that is exposed can be inserted in the objective body now, for example human or animal's tissue or any other material or the device in, for example be used for laboratory, place facing to the target that receives in advance, caused the generation of inserting thereby thrust to move but this device front is preferred.Preferably syringe needle or container are pinned thrusting the terminal position place, and preferably send and to listen or tangibly signal, allow user confirm to thrust fully by locking device etc.Can carry out injecting step now.This can utilize moving continuously of control knob to carry out, but preferably, change the Move Mode of the button that is used to inject, preferably relate to and unclamp step so that return the position of beginning, and be most preferred, inject thereby begin new moving from initial position.In injection, can utilize button to carry out several injection stroke, especially for relatively large injection or as weak patient's adjustment.When removable wall arrive container ends or arrival be arranged in the actuating device stop the adjacent part on surface the time, injection is finished and can be perceived as stopping of button.Preferably trigger automatically or by the operator now and carry out syringe needle and return step.Triggering can be undertaken by trigger independently, by the release of control button, perhaps at first carries out when button is operated once more.Although can remove syringe needle from target before syringe needle returns step, preferably this result who removes as the needle retractable step takes place.

Although above-mentioned steps is described according to given order, within the scope of the invention, other order also can be used, unless provide opposite special instruction.

From the description of following specific embodiments with reference to the accompanying drawings, will know more and understand detail of the present invention.

Summary of drawings

Figure 1A and 1B have generally illustrated the syringe with the driving member that comprises connecting device with two states, are used to transmit the power that is applied on the control button.Fig. 1 C demonstrates the modification with fixed container and movable syringe needle.

Fig. 2 A to 2G demonstrates the detailed embodiment of syringe in several operational phases.Fig. 2 A is the decomposition view of this device feature, and Fig. 2 B to 2G demonstrates each operational phase in height and width segments.

Fig. 3 has illustrated the similar embodiment with Fig. 2, but changing part is that hinged door is arranged in front.

Description of drawings

Figure 1A and 1B have generally illustrated the syringe with actuating device, and this actuating device comprises and is used to transmit the connecting device that is applied in the power on the control knob.In Figure 1A, schematically control knob is in the enable position, and control knob is in the position of pressurized in Figure 1B.Syringe by 100 expressions comprises with the housing shown in theimaginary line 110 generally, and it has the lateral opening 112 that is used to expose thefront openings 111 of syringe needle and is used for control knob.Length 113 shown in this housing has and height 114 and perpendicular to the width (not shown) of height and length.Thecontainer 120 of injection cast is arranged in the housing, and comprises bobbin 121, hasprevious section 122, the back bobbin end 124 of syringe needle 123 and be theremovable wall 125 of the piston form that is inserted in thebobbin.Container 120 is configured to axially move at the back location shown in Figure 1A with between the anterior locations shown in Figure 1B in housing 110.Generally by the control knobs of 130 expressions can be said to be comprise can be manual parts 131, it rotates and the deflection initial position around the axis 132 that extends along the housing width under the effect of button spring 133, away from housing.By applying the ARTIFICIAL FORCE by the sensing housing shown in the arrow 134, button parts 131 just can overcome the power of button spring 133 and move in the depressed position shown in Figure 1B.Should be noted that, be applied to ARTIFICIAL FORCE on the button along the direction of arrow 134 and have component perpendicular tocontainer 120 axis, but this power not straight from the shoulder with described axis normal.In addition, this angular relationship can some variation between the position shown in Figure 1A and the 1B owing to the cause of the rotational motion of control knob.It should also be noted that control knob is positioned at the side of container axis and not coaxial with it, and between the correspondingaxial end portion 122 and 124 ofcontainer 120, have pressing position 134.Driving member 140 here can be said to be and comprise the connecting device that is made of the first arm 141 andsecond arm 142, the first arm 141 one end thereof link to each other with control knob in first knuckle joint 143, and its another end links to each other with the front end of roughly axialsecond arm 142 insecond knuckle joint 144, and these joints make the rotational motion in the plane of these figure to carry out.The first arm is configured to like this, promptly moves forward at control knobsecond knuckle joint 144 in arrow 134 direction pressurizeds.In this case it drive second arm front end forward, and because second arm is axially to be provided with basically, so its rear end also will move forward.In order to ensure desired forms of motion, for example avoid the first arm to topple over backward, guide can be provided, the guide frame that is guide rail or form of slots perhaps is provided on housing, perhaps as shared in the connecting device like that with imaginary line and with the other connector shown in the 3rd arm 145, its installation is used for arriving the first arm in the 3rd knuckle joint 146 places rotational motion, and its another end is installed on the housing so that rotational motion at the 4th joint 147 places.Obviously said apparatus will be applied to the axially-movable that vertical force component on the control knob converts the aft section of second arm to, place, end at second arm is provided with a kind ofpromotion structure 149, this shown impeller is the ratchet with flat driving front surface and taper protrusion rear surface, is used for to be used on the container.Described so far drive disk assembly can be said to be for this device thrust device and injection device is common.Other details of thrusting device in this embodiment is simple, and to can be said to be the cooperation that comprises betweenimpeller 149 and back bobbin end 124, thereby allows impeller thatcontainer 120 is moved to anterior locations the position from behind.The further details of injection device can comprise jumper bar 161, and it is used to act onremovable wall 125, hastooth 162, is shown the ratchet of the front surface of the convergent with flat rear surface and protrusion among the figure, is used for cooperating with impeller 149.Push rod 149 andtooth 162 also can be used as the switched system that is used for this device, therebyimpeller 149 can at first be acted on the bobbin 121 so that thrust, and catchjumper bar tooth 162 then so that injection.It is the system that reconnects as this device that impeller 149 and a plurality oftooth 162 also can be said to, thereby allows control knob pressurized and unclamping so that carry out successive injection movement repeatedly.Also schematically demonstrate breech lock 180, it has unci 181, and it is towards container bobbin 121 bias voltages and can last move in the back of bobbin end 124 and prevent to move backward during step subsequently what thrust motion.

Figure 1A has illustrated the original state of this device feature.Along the direction of arrow 134 power is applied to button parts 131 will be rotated around axis 132, thereby make the first arm 141 under the 144 proal effects of second knuckle joint, rotate, thereby also drivesecond arm 142 forward with theimpeller 149 of back around first knuckle joint 143.Impeller 149 will mesh back bobbin end 124 in this first motion, and thecontainer 120 that comprises jumper bar 161 is moved forward, thereby syringe needle is exposed athousing 110front openings 111 places.Last in this motion, the unci 181 of breech lock 180 will mesh back bobbin end 124 to prevent that container from moving backward.In Figure 1B, demonstrate this state of this device.In case button 130 unclamps, spring 133 will make it get back to it at the initial position shown in Figure 1A, but breech lock 180 will prevent that container from moving back.On the contrary, the motion backward that turns back to the causedimpeller 149 of its initial position by control knob will be crossed one orseveral tooth 162 of jumper bar 161 by the combined effect that being used on impeller and tooth meshed the conical surface of jumper bar 161.Therefore described parts are as switched system, are used for allowing button unclamp carrying out and move stage of action of injection and switch from thrusting.Then control knob pressurized once more, and travelling forward of theimpeller 149 that is produced will drive jumper bar 161 forward by the effect ontooth 162 now, roughly 149 ' locating by shown in the dotted line in Figure 1B.Where necessary or when requiring the injection doses, button can unclamp and once more pressurized to meshnext tooth 162 backward so that carry out repeatedly injection stroke.Therefore the mechanism of ratchet that is provided byimpeller 149, back bobbin end 124 and a plurality oftooth 162 and ratchet type will be as a kind of system that reconnects, and is used for allowing carrying out on control knob effect repeatedly.

Fig. 1 C schematically illustrates the modification of the embodiment of Figure 1A and 1B, and wherein container is fixed and motion syringe needle has no truck with in syringe.In the figure, it is multiple having onlysecond arm 142,second knuckle joint 144 and theimpeller 149 of connected system.Can axially movable syringe needle 123 ' demonstrate and have medial side face opening 126 and havecover plate 127 at its tail end, this cover plate makes syringe needle also surperficial as promoting when its back location moves to its anterior locations, and this cover plate is configured to be driven by theactivation configuration 150 on second arm 142.Container 120 ' demonstrates in container front 120 ' and locates to have extension, side 128, and this extension, side 122 ' can be penetrated by syringe needle 123 ', thereby syringe needle opening 126 communicates with regard to appearing in the extension, side and with the internal flow ofcontainer 120 '.Container 120 ' inhousing 110, be arranged in the roughly the same position of Figure 1B on, and jumper bar 161 ' be arranged in in the roughly the same position of Figure 1A, thereby have a segment distance between jumper bar 161 ' front end andremovable wall 125, this distance is substantially equal to by the haul distance of thrusting shown in the arrow 151.Jumper bar 161 ' has additional tooth 162 ', is used for that up toremovable wall 125, this tooth contacts withimpeller 149 at the beginning driving it at the beginning.

In Fig. 1 C, this device shows with solid line before thrusting, and demonstrates with imaginary line after thrusting.The pressurized first time of control knob will makesecond arm 142 move forward one section length corresponding to arrow 151.In this motion, as described, under syringe needle stings situation throughhousing 110 front openings 111 ' simultaneously,actuator 150 will drivecover plate 127 so that syringe needle 123 ' moves forward and passes extension, container 120 ' side 128 and be communicated with to form described fluid.Syringe needle 123 ' is fixed in this position by the locking devicen of friction or any appropriate.In identical motion, theimpeller 149 that affects tooth 162 ' will drive jumper bar 161 ' forward, roughly contactremovable wall 125 up to it.The same at Figure 1A and 1B, unclamping of control knob will make impeller move to cross and to catch thetooth 162 of more close back backward.Pressing button will make jumper bar 161 ' andremovable wall 125 move forward continuously repeatedly, thereby make the liquid in the container 120 ' pass syringe needle 123 ' outflow so that inject by extension, side 128 and opening 126.As before, suppose that jumper bar 161 ' is prevented from backward moving, for example by friction, additional ratchet and ratch mechanism or other device arbitrarily.

Can change in every way in the schematic apparatus shown in Fig. 1, for example according to top detailed explanation.For example this device can be equipped with response agency, for example is used for unclamping breech lock 180 by returning spring and the structure in the rear face office of jumper bar 161.On jumper bar, can be provided with dosing mechanism.Can be provided for starting the feature of this device.Described connected system can for example replace based on the driving member type of line or wheel with other.In the embodiment of Fig. 1 C, injection cast container can replace with any pump installation, for example is used for aspirating cylinder/piston type with injector stroke repeatedly by check valve, and this will make container select is fully freely, comprises for example soft bag.

Fig. 2 A to 2G demonstrates the detailed embodiment of the syringe in several operational phases, comprises setting up procedure, dosage setting step, thrusts, injection and needle retractable.These device features will mainly be described by reference Fig. 2 A and 2B, and these figure demonstrate these device features and be applicable to the device that is assembled that is supplied to the user in original state.Syringes by 200 expressions comprise thehousing 210 that is made of two and half ones generally, have theopen front 213 that is used to expose syringe needle and container, be used for thelateral opening 212 of control knob and be used for theback opening 213 of quantitative screw.Injection cast container 220 is arranged in the housing and comprisesbobbin 221, hasfront portion 222, theback bobbin end 224 ofsyringe needle 223 and be theremovable wall 225 of the piston form that is inserted in the bobbin.This container is enclosed in thesupport 226 that is local sleeve and box form, it hasrear flange 227, is used for fixingback bobbin end 224, and is used for accepting the syringe needle installed part at its front end place, and has theradial stop pin 228 that has the part that extends back, so that the motion of limit bracket.In Fig. 2 B, support is at place, the end of its front, thereby not only is exposed to the outside ofhousing front openings 211 with syringe needle but also the container previous section, andlatch 228 is in connection with the inside of housing previous section.From this position, support can be moved by the artificially backward by adopting the handle of locating in two sides of housing that can contact outside 229, and these handles partly link to each other with bracket sleeve tube by the cervical region that moves in slit 214 along the housing side.Being can be said to by the control knobs of 230 expressions generally is that comprise can manually operatedpart 231, thebutton axis 232 that this part is extended around the width along housing rotate and under the effect ofbutton spring 233 from housing towards the position bias voltage of shrinking away from theshell body farthest.But in Fig. 2 B, this button demonstrates the state that is in its pressurized and is fixed in this state bybutton hook 234, thisbutton hook 234 has backhook 235 parts, is used for being subjected at the Shi Houyu that support moves backward the button andfront end 236 engagements ofhandle 229 effects.This button also has twocams 238 and 238 ', has one on each side of support, and thefront cam face 239 of cam has circular covering of the fan form, is the center withbutton axis 232, and is provided with the tooth corresponding to the gear that will describe.Be not to be described to the general button notion of a part, but these cams can optionally be considered to the part of the general driving member notion that will describe.As in the embodiment of Fig. 1, the power that is applied on the button has at least one component perpendicular tocontainer 220, and this button is positioned at the side of container axis and at least partly along container.Can be said to be by 240 driving members of representing generally is to comprisetoothed gear 241, it has twoouter bull wheels 242 and 242 ' and theless steamboat 243 of intermediary diameter, another kind of gear ratio is provided, they are arranged to be fixed on thecommon wheel axle 244 mutually, be supported in the bearing 245 that is fixed on the housing, but be exaggerated along housing short transverse at least, thereby gear can be moved up and break away from the tooth bar that will describe.Bull wheel 242 and 242 ' always withcam face 238 and 238 ' engagement so that clockwise rotate (as shown in Figure 1A) the time marquis of button pressurized, and the marquis rotates counterclockwise when button unclamps.Described so far drive disk assembly is considered to thrust device and injection device is common.It is to comprise that other parts that thrust device can be said to be:thrust sleeve 250, it between its back and anterior locations round and axially drivingcontainer 220 and itssupport 226, comprise two toothed guide rails 251 and 251 ' that thrust, it separates so that match withbull wheel 242 and 242 '; Ratchettooth bar 252 with the tooth that turns forward is used with similar structures on described shot sleeve and is matched; Be used for the lock bolt 254 that the pinning part 253 and being used for of the cervical region oflock handle 229 matches with breech lock at the container of described forward facing position.It is to compriseshot sleeve 260 that other parts of injection device can be said to be, and it is round thrusting sleeve and comprising described jumper bar and the dosage set parts.This shot sleeve comprises: two toothed injection guide rails 261 and 261 ', its setting are used for matching withsteamboat 243; Have sweptback tooth so that theinternal pawl 262 that matches withratchet tooth bar 252 on thrusting sleeve, thereby just guarantee shot sleeve with respect to thrusting telescopic travelling forward; Nut teeth 263, be used for dose setting device in threads engaged; Inclined-plane 264 is used for unclamping described breech lock; And thespring support 265 that is used for described returning spring.Dose setting device 270 comprises frontjumper bar part 271, it is provided with and is used for acting on during injecting on theremovable wall 225, has threadedmid portion 272, its supporting surface matches with the nut teeth 263 ofshot sleeve 260, and the dosage setting handle 273 of back, it can carry out manual operation by housing back opening 213.Breechlock 280 on enclosure interior has elastomeric element 281, it is towardscontainer 220 bias voltages and be configured to and can be bent upwards and move down in last lock bolt 254 back of thrusting on thesleeve 250 of thrusting motion, thereby prevents motion backward during injecting step subsequently.The inclined-plane 264 that is latched inshot sleeve 260 arrivebreech locks 280 and rise elastomeric element 281 the time marquis the unclamping once more at last of injection stage, (this shot sleeve always irrespectively moves same distance with dosage setting) returns step thereby start syringe needle.It is also to comprise returningspring 291 in addition thatreturn mechanism 290 can be said to be, and acts on thrusting thespring support 265 on thesleeve 260 and be fixed between thepedestal 292 on the housing.

Fig. 2 B has illustrated the original state of this device withbutton 230 that end in front is locked and container 220.This device can be with this pattern supply, and general syringe needle is not installed in the front of container.User step at first issyringe needle 223 to be installed in thecontainer front 222 of exposure, and removes the needle shield of any existence.Fig. 2 C demonstrates this device after these steps.User is held this device and is allowed syringe needle upwards, and catches and promotebackward side handle 229, is engaged on up to their cervical region and pins in the part 253, as shown in Fig. 2D.Container 220 is locked with itssupport 226 thereby with respect to thrustingsleeve 250, and the distance of being moved is fit to be used for the container front and syringe needle is hidden in the housing fully and the back, edge of housing front openings 211.In identical motion,handle 229 reaches thefront end 236 ofbutton hook 234 and makes the mobile backwardhook 235 to unclamp the back of this button hook, so that throw offbutton 230, this button is moved on the remote locations of preparation effect in the effect of button spring 233.Also match in the position ofjumper bar 271 ends indose setting device 270, thereby it is in connection withremovable wall 225 and makeremovable wall 225 move a segment distance during the decline in container motion before the pinning ofhandle 229, and this is used for removing the air in the container.If require less than maximal dose, then user can rotatedosage setting handle 273 with mobiledose setting device 270 and makejumper bar 271 backward, thereby between jumper bar andremovable wall 225, form a segment distance, this distance is carried out travelling forward of standard corresponding to left amount after injection becauseshot sleeve 260 is configured to be independent of dosage setting.User can makehousing front openings 211 contact and press thebutton 230 with injection position now, this button will at firstactuate cam face 239 and 239 ' to guaranteegear shaft 244 in bearing 245 andbull wheel 242 and 242 ', to move down with thrust guide rail 251 and 251 ' engagement, makegear 241 clockwise rotate (Figure 1A) then, thereby promote to thrust sleeve and makecontainer 220 forward up to the elastic arm 281 that thrusts sleeve lock bolt 254 engagement breech locks 280.As being clear that in Fig. 2 E, this motion makessyringe needle 223 be exposed to housing front openings front and thrusts to fix a point, and makesdosage setting knop 273 move to untouchable position in the housing.This motion is shorter than the motion backward of the container that carries out at first by knop 229.This is for the exposure of correct restriction syringe needle and thefront 222 that can not expose container, and this just is used for making things convenient for syringe needle to install at first.Ratchet 262 in this motion on theshot sleeve 260 and thrust being meshing with each other between theratchet tooth bar 252 on thesleeve 250 and guarantee that theshot sleeve 260 that comprises dose settingdevice 270 is also driven forward.Therefore thrusting the power that overcomes returningspring 291 of moving carries out, if and button unclamps thrusting any time ofsleeve 250 before having been caught bybreech lock 280, then returningspring 291 will return at syringe needle and be with these parts to return once more under the effect of removing, and select thereby allow to carry out new target location.After the engagement ofbreech lock 280,release button 230 will make it move back to its initial position in idle running, thereby throw off because make itsaxis 244 in bearing 245 rise and thrust guide rail 251 and 251 ' in the power backward on the gear 241.In the position that is locked, the steamboat 43 ofgear 241 has arrived the top position ofinjection guide rail 262 and 261 ', and bull wheel is in the place, end of thrusting guiderail.Pressing button 230 will make steamboat complete andguide rail 262 and 261 ' engagement next time, and thesleeve 250 that thrusts that will makeshot sleeve 260 with respect to being locked that clockwise rotates ofgear 241 moves forward.Therefore will be at the related parts of the infall of guide rail as switched system, thus allow to change from penetrating into to inject.Steamboat will during injection stage, provide power to amplify than minor diameter, thereby require bigger button motion so that carry out corresponding sleeve motion.For whole the moving forward ofshot sleeve 250, need on button, carry out stroke several times.Also have, any unclamping of button will throw offsteamboat 243 and guide rail 261 and 261 ', and returns once more during the button pressurized, andratchet 262 andratchet tooth bar 252 prevent the motion backward arbitrarily ofshot sleeve 260 simultaneously.Therefore described parts are as a kind of system that reconnects, and effect is repeatedly carried out in permission on button.Operator can adopt the combination of all or part of button stroke to move forward to its predetermined end position fully up to shot sleeve during injection stage, as as shown in Fig. 2 F, the elastomeric element 281 ofbreech lock 280 is risen, thereby make returningspring 291 can make thecontainer 220 of band syringe needle,thrust sleeve 250, being integrated into ofshot sleeve 260 and dose settingdevice 270 is retracted in the housing under the help that less button unclamps shortlyer, still do not expose from having hidden syringe needle anddosage setting knop 273, as shown in Fig. 2 G.In this final position, the part that extends back oflatch 228 is used for by stoping steamboat further withguide rail 262 and 261 'engagement wheel axis 244 for good and all to be risen on the not position engaged above it, thereby also makesbutton 230 losses of function.Because all critical components and operation are controlled of no use now or have been hidden, so this device can go out of use safely.

In the embodiment of Fig. 3, housing 310 includes hinged door 315 in the front of device, and this has the front openings 311 that is used for syringe needle, and can rotate around axis 316.On the inside of door 315, have from untie-sell 317 (dotted line), the track 355 (dotted line) that is used for on the top extension 356 of thrusting sleeve 350 is set matches.This control knob 330 also comprises temporary transient breech lock 337 here, matches with locking mechanism on the door.Button spring 333 is made a kind of coil spring here.Be provided with at the tight parts 319 of the door lock on door and the housing and 319 ' respectively and be used for when closing fully, door for good and all being pinned.As in the embodiment of Fig. 2, this device includes driving member 340, have a housing 320 thrust sleeve 350, shot sleeve 360 and dose setting device 370, it has dosage setting knop 373 and has front jumper bar parts 317 at housing back opening 313 places, this parts setting is used for and is used on the removable wall 325 of container breech lock (not shown) and syringe needle return mechanism 390 at the last place of thrusting.

Fig. 3 demonstrates this device and is in original state, and wherein it can be consigned to the terminal use.This user is at first removed the needle shield at part place in front, and preferably door is designed to jointly prevent that with cover a sealing is removed up to cover.The suggestion user made syringe needle be directed upwards towards before closing door, because deacration and pilot injection carry out simultaneously.When door 315 is closed around axis 316, pin driven member 317 matches with track 355 and presses backward will thrust sleeve 350, this will also drive shot sleeve 360 and dose setting device 370 moves backward, removes the back of front openings 311 and dosage setting knop 373 is exposed at housing back opening 313 places thereby syringe needle is returned.In the decline of motion backward, the shot sleeve 360 that has dose setting device 370 is leaned on the shell structure (not shown), thereby remaining motion is undertaken by the sleeve 350 that thrusts that has container 320 that is pressed against on the parts that are blocked, thereby front jumper bar part 371 makes removable wall 325 move forward with respect to the container 320 that still moves, and this moves and is applicable to and removes air and pilot injection.Also have in 315 down periods of door, the temporary transient breech lock 337 of button 330 is thrown off with the locking mechanism of door 318, thereby button 330 is being discharged on its remote position the preparation effect under the effect of button spring 333.When door was closed fully, the tight parts 319 of door lock and 319 ' for good and all mesh and allow track 355 be in its lower end from untie-sell 317 can freely-movable so that thrust sleeve 350.This device is prepared now to use with the described the same mode of Fig. 2, for example carry out random dosage setting with knop 373, action button 330 is carried out syringe needle and is thrust, and the pressing button one or many injects with automatic needle when shot sleeve arrives its forward terminal and returns repeatedly.

Embodiment with the embodiment explanation is exemplary, in no case should be understood that to limit scope of the present invention or generality as being limited in the claims.

In general, the classification of illustrational these device features and parts group and their situation that is connected the various general concepts that adopted should not be understood that restrictive or enforceable, as long as these parts can satisfy the function of being wanted or the performance of described notion.

Claims (98)

1. injection device, it is used to have with the injection syringe needle or is used for the container of the opening of injection needle, it is the syringe type that this container can be selected, it has the section bobbin of constant vertically, the opening that is used for syringe needle is arranged on the bobbin front portion, and in this bobbin, be inserted with at least one and optional a connected removable wall of piston rod arranged, this injection device that is used for container comprises a) housing, b) bearing or support, setting is used for holding syringe needle or container and makes it can be with respect to housing at the back location that covers syringe needle with expose between the anterior locations of syringe needle and move along axial direction, c) thrust device, can operate and be used for making syringe needle to move to anterior locations in the position from behind, d) a Ren Xuan return mechanism, at least can operate and be used for making syringe needle to move along backward direction, e) injection device, at least can operate the content that is used for by the syringe needle jetting container, and f) at least one is arranged on the control knob on the housing, and can operate at least and be used for starting the operation of thrusting device and/or injection device, it is characterized in that its improvements comprise:

Independent or whole actuating device will thrust device and injection device and introduce and be connected to described button, thereby make that being applied in manual capacity regulator on the button can be transmitted to and thrust device and/or injection device, so that it operates, and

Switched system, the manual capacity regulator that allows to be applied on the button carries out the stage switching, thrusts device at first to operate, and operates injection device then.

2. injection device as claimed in claim 1 is characterized in that, this thrusts device is arranged to act directly on syringe needle, container or the support.

3. injection device as claimed in claim 1 is characterized in that, described button setting is used for moving, and its at least one component is perpendicular to needle axis.

4. injection device as claimed in claim 3 is characterized in that, the converting motion that described button setting is used for being directed.

5. injection device as claimed in claim 3 is characterized in that, described button setting is used for proceeding to rotatablely moving of small part around rotation axis.

6. injection device as claimed in claim 5 is characterized in that, described rotation axis is substantially along described housing width orientation.

7. injection device as claimed in claim 1 is characterized in that described button is positioned at the side of needle axis.

8. injection device as claimed in claim 7, it is characterized in that described button to small part between the container axial end portion.

9. injection device as claimed in claim 3 is characterized in that described actuating device comprises to redirect device, is used for the power on the button of being applied to is redirected to being used for moving axially of syringe needle and/or removable wall.

10. injection device as claimed in claim 9 is characterized in that the described system of redirecting is mechanical.

11. injection device as claimed in claim 10 is characterized in that the described system of redirecting comprises any element of selecting from line, band, connected system or leverage.

12. injection device as claimed in claim 12 is characterized in that the described system of redirecting comprises wheel, is preferably toothed the wheel.

13. injection device as claimed in claim 1 is characterized in that described actuating device comprises the power converting member.

14. method as claimed in claim 13 is characterized in that described power converting member provides a ratio to thrust gear ratio higher gear ratio in the device in injection device.

15. injection device as claimed in claim 1 is characterized in that described switched system makes it possible to predetermined axial positions between syringe needle and housing and carries out the stage and switch.

16. injection device as claimed in claim 15 is characterized in that described position is in the anterior locations of syringe needle or near this position.

17. injection device as claimed in claim 15 is characterized in that described switched system is included in the breech lock that is used for syringe needle in the described position.

18. injection device as claimed in claim 15 is characterized in that a kind of structure, the position that it has basic fixed with respect to housing, and be provided be used for redirecting, release or exert all one's strength is applied on the button to be used for the injection device operation.

19. injection device as claimed in claim 15 is characterized in that in described position, can carry out the stage switching within the moving range of actuating device.

20. injection device as claimed in claim 19 is characterized in that described switched system comprises ratchet and ratchet type mechanism.

21. injection device as claimed in claim 15 is characterized in that described power is applied in the intravital constant position of shell place, thrusts motion the workpiece of injection device is taken in the described position.

22. injection device as claimed in claim 21 is characterized in that described workpiece is the jumper bar device that is used to inject the cast container.

23. injection device as claimed in claim 21 is characterized in that at least one is taken turns at described constant position place to apply power.

24. injection device as claimed in claim 22 is characterized in that gear ratio occurring in stage switching place changes.

25. injection device as claimed in claim 1 is characterized in that breech lock is provided for syringe needle is at least temporarily remained in the anterior locations.

26. injection device as claimed in claim 1 is characterized in that one reconnects system and allows button to carry out repetitive operation.

27. injection device as claimed in claim 26 is characterized in that this reconnects system and transmits power at button when a direction moves, and changes along another direction Mobile Space-time and work as this button.

28. injection device as claimed in claim 26 is characterized in that this reconnects system and allows reversible stage action.

29. injection device as claimed in claim 26, it is reversible it is characterized in that thrusting mobile.

30. injection device as claimed in claim 26 is characterized in that reconnecting system and allows to carry out pump action on button, is used for the intermittently operated of injection device.

31. injection device as claimed in claim 30 is characterized in that being used to injecting the non-return device of the removable wall of cast container, it prevents that removable wall from moving backward.

32. injection device as claimed in claim 26 is characterized in that the system that reconnects comprises that at least one has the wheel that is used to mesh the movable axle that unclamps.

33. injection device as claimed in claim 1, it is characterized in that described button with respect to housing to an end position bias voltage, preferably to the remote location bias voltage.

34. injection device as claimed in claim 1 is characterized in that return mechanism is arranged.

35. injection device as claimed in claim 34 is characterized in that the energy stored by utilizing, preferably thrust move in energy in the compressed balancing spring, carry out syringe needle and return.

36. injection device as claimed in claim 35 is characterized in that this returns is that effect by on button triggers.

37. injection device as claimed in claim 35 is characterized in that this returns is that predetermined point place in injection process is triggered automatically.

38. injection device as claimed in claim 1 is characterized in that this injection device comprises dosing mechanism.

39. injection device as claimed in claim 1 is characterized in that this bearing or support are provided under the situation that removable wall moves forward with respect to the container bobbin, allows injection cast container to move backward towards housing.

40. injection device as claimed in claim 39, the displacement that it is characterized in that removable wall are applicable to makes that removable wall is deviate from, degasification, pilot injection or formulation mix.

41. injection device as claimed in claim 39 is characterized in that being used to the lever that container is moved.

42. injection device as claimed in claim 40 is characterized in that this lever comprises hinged door.

43. injection device as claimed in claim 41 is characterized in that this leverage is an amplification power.

44. injection device as claimed in claim 1, the ratio that it is characterized in that the maximum height of defined housing and defined Breadth Maximum is preferably greater than 1.5 greater than 1.

45. injection device as claimed in claim 1, the ratio that it is characterized in that the greatest length of defined housing and defined maximum height is less than 4, preferably less than 3.

46. injection device as claimed in claim 1 is characterized in that described container is the container of two or more chamber profile.

47. injection device as claimed in claim 46 is characterized in that this container that is installed on the housing comprises screw thread, its length adapts with the displacement that is used for making chamber contents merge necessary removable wall.

48. injection device as claimed in claim 1 is characterized in that syringe needle is configured to move with respect to container.

49. injection device as claimed in claim 48 is characterized in that container immovably is arranged in the housing.

50. the injection device of any one claim is characterized in that container is the injection cast, has the syringe needle that is mounted so that carry out common moving axially as described above.

51. injection device, it is used to have with the injection syringe needle or is used for the container of the opening of injection needle, this container can randomly be the syringe type, it has the section bobbin of constant vertically, the opening that is used for syringe needle is arranged on the bobbin front portion, and in this bobbin, be inserted with at least one and optional a connected removable wall of piston rod arranged, this injection device that is used for container comprises a) housing, b) bearing or support, setting is used for holding syringe needle or container and makes it can be with respect to housing at the back location that covers syringe needle with expose between the anterior locations of syringe needle and move along axial direction, c) thrust device, can operate and be used for making syringe needle to move to anterior locations in the position from behind, d) a Ren Xuan return mechanism, at least can operate and be used for making syringe needle to move along backward direction, e) injection device, at least can operate the content that is used for by the syringe needle jetting container, and f) at least one is arranged on the control knob on the housing, and can operate at least and be used for starting the operation of thrusting device and/or injection device, it is characterized in that its improvements comprise:

This button is arranged on the housing, thereby allows to be rotated or translational motion with respect to housing, and described motion has at least one component motion perpendicular to needle axis,

Independent or whole actuating device, thrust device to the major general and introduce and be connected to described button, thereby the feasible manual capacity regulator that during movement is applied on the button can be transmitted to and thrust device so that it is operated, thereby syringe needle is partly moved to the anterior locations of exposing syringe needle from the back location that covers syringe needle at least.

52. injection device as claimed in claim 51 is characterized in that at the arbitrary characteristics described in the aforementioned 1-50.

53. injection device, it is used for the container of syringe type, comprise the section bobbin of constant vertically, one open front and at least one removable wall, can randomly have a connected piston rod, it inserts in the described bobbin, to be used to that container contents is moved, this injection device comprises a) housing, b) bearing or support, and setting is used for holding syringe needle or container and it can be moved along axial direction with respect to housing, and c) injection device, can operate be used for making at least container removable wall along forwards to moving, it is characterized in that its improvements comprise:

This bearing or support are provided for forward during displacement, allowing container to move backward towards housing with respect to the container bobbin at removable wall, and

The hinge lever that is used for mobile containers.

54. injection device as claimed in claim 53 is characterized in that the displacement of removable wall is suitable for making removable wall disengagement, degasification, pilot injection or formulation to mix.

55. injection device as claimed in claim 53 is characterized in that this lever comprises hinged door.

56. injection device as claimed in claim 53 is characterized in that this lever is to be used to carry out power amplify.

57. injection device as claimed in claim 56 is characterized in that the arbitrary characteristics described in claim 1-52.

58. the operational approach of injection device, this injection device is used to have with the injection syringe needle or is used for the container of the opening of injection needle, this injection device comprises a) housing, b) bearing or support, setting is used for holding syringe needle or container and makes it can be with respect to housing at the back location that covers syringe needle with expose between the anterior locations of syringe needle and move along axial direction, c) pump machanism, can operate the content that is used for by the syringe needle jetting container, d) at least one control knob, can operate and be used for making syringe needle to move and/or start this pump machanism along axial direction, this method comprises the following steps: i) make syringe needle position from behind move to the position of front, ii) come content by the syringe needle jetting container by starting this pump machanism, and iii) optionally make syringe needle move to back location from anterior locations, it is characterized in that its improvements comprise:

Manual force is applied on the button so that it moves,

Be delivered to syringe needle to small part power, move a part from the back location that covers syringe needle at least to the anterior locations of exposing syringe needle in operation for the first time, to make it, and

For the first time after the operation, be delivered to pump machanism to small part power, come content by the syringe needle jetting container.

59. method as claimed in claim 58 is characterized in that in operation for the first time, power is transmitted by power being applied directly on syringe needle, container or the support.

60. method as claimed in claim 58 is characterized in that described button moves with respect to the mode of housing with rotation or translational motion, described motion has at least one component motion perpendicular to container axis.

61. method as claimed in claim 60 is characterized in that the power on the button of being applied to is re-oriented into the step of axial force.

62. method as claimed in claim 58, it is characterized in that being applied on the button move with syringe needle mobile in operation for the first time between ratio greater than 0.1 and less than 10.

63. method as claimed in claim 58 is characterized in that in operation for the first time and occurs power for the second time between the operation amplifying.

64. method as claimed in claim 58 is characterized in that for manipulating the operation for the first time and the second time single button motion.

65. method as claimed in claim 58 is characterized in that button is unclamped to small part in operation for the first time, syringe needle moves a part at least backward in reversible mode.

66. method as claimed in claim 58 is characterized in that button is unclamped to small part and moves in the opposite direction between operation for the first time and operating for the second time.

67. method as claimed in claim 58 is characterized in that movable button carries out the step of operation for the second time for the second time.

68. method as claimed in claim 58 is characterized in that movable button carries out the step of operation for the second time several times.

69. method as claimed in claim 58 is characterized in that for the first time and between the operation syringe needle for good and all or temporarily is locked in the step of anterior locations for the second time.

70. method as claimed in claim 58 is characterized in that making syringe needle move to the step of back location from anterior locations in the operation for the third time after operation for the second time.

71., it is characterized in that triggering the step of operation for the third time by operating a control piece as the described method of claim 70.

72., it is characterized in that the step of using control knob to trigger as the described method of claim 71.

73., it is characterized in that after operation for the second time by unclamping the step that control knob triggers as the described method of claim 72.

74., it is characterized in that again the step that movable button triggers as the described method of claim 72.

75., it is characterized in that the step of operating for the third time with predetermined container contents as the described method of claim 70.

76., it is characterized in that the step of operating for the third time by the energy that release is stored as the described method of claim 74.

77. method as claimed in claim 58 is characterized in that setting the step of the dosage that will spray.

78. method as claimed in claim 58 is characterized in that the step of coming primer pump mechanism by the door that moves on this device.

79. the operational approach of injection device, this injection device is used to have with the injection syringe needle or is used for the container of the opening of injection needle, this injection device comprises a) housing, b) bearing or support, setting is used for holding syringe needle or container and makes it can be with respect to housing at the back location that covers syringe needle with expose between the anterior locations of syringe needle and move along axial direction, c) pump machanism, can operate the content that is used for by the syringe needle jetting container, d) at least one control knob, can operate and be used for making syringe needle to move and/or primer pump mechanism along axial direction, this method comprises the following steps: i) make syringe needle position from behind move to the position of front, ii) come content by the syringe needle jetting container by primer pump mechanism, and iii) optionally make syringe needle move to back location from anterior locations, it is characterized in that its improvements comprise:

Apply manual force so that button moves in the mode of rotation or translation with respect to housing, described motion has at least one component motion perpendicular to container axis,

Be delivered to syringe needle to small part power and move a part from the back location that covers syringe needle at least to the anterior locations of exposing syringe needle in operation for the first time, to make it.

80., it is characterized in that the arbitrary steps of claim 58-78 as the described method of claim 79.

81. the operational approach of injection device, this injection device is used for the syringe type of container, comprise its section bobbin of constant in the axial direction, the opening of front and at least one are chosen wantonly a connected removable wall of piston rod, this removable wall is inserted in the bobbin, be used to make container contents to move, this injection device comprises a) housing, b) bearing or support, setting is used for holding syringe needle or container and allows them to move along axial direction with respect to housing, c) injection device can operate being used for making the removable wall of container to move along front direction at least, and d) be installed in the hinge member on the housing, it is characterized in that its improvements comprise:

Move this hinge member, and

The motion of hinge member converted under the situation that removable wall moves forward with respect to the container bobbin, make container towards housing motion backward.

82., it is characterized in that carrying out removable wall disengagement, degasification, pilot injection and/or the blended step of formulation by moving of removable wall as the described method of claim 81.

83. as the described method of claim 81, it is characterized in that hinge member is a closable door, closing as hinge member of it moved.

84., it is characterized in that by closing a step of next closed at least a portion container as the described method of claim 83.

85., it is characterized in that coming the step of start-up control button to operate by the motion of hinge member as the described method of claim 81.

86., when it is characterized in that on being applied in removable wall, will be applied to the step of the power amplification on the hinge member as the described method of claim 81.

87., it is characterized in that the arbitrary step among the claim 58-80 as the described method of claim 81.

88. be used to inject the injection device of cast container, comprise its section the opening of bobbin, the front of constant and at least one are optional in the axial direction a connected removable wall of piston rod arranged, this removable wall is inserted in the bobbin, be used to make the content of container to move, this injection device comprises a) housing, b) bearing or the support that is used for holding syringe needle or container is set, c) injection device, can operate and be used for making at least the removable wall of container to move along direction of advance, it is characterized in that its improvements comprise:

This injection device comprises at least one guide rail, and part is coaxial or parallel at least with the bobbin axis for it, and constitutes or be connected on piston rod or the jumper bar device, so that removable wall is moved along direction of advance at least,

The driving wheel that has rotating shaft, described axle directly or indirectly links to each other with housing, and can move between two shaft positions, and this is taken turns in primary importance and is meshed with guide rail, is used to make it to move with respect to housing, and this is taken turns in the second position and throws off with guide rail.

89., it is characterized in that this guide rail and wheel have corresponding tooth as the described injection device of claim 88.

90. as the described injection device of claim 88, it is characterized in that an actuator is connected to housing in a movable manner, and optional be connected to driving wheel, be used for when actuator moves, making its rotation by intermediate member or wheel.

91., it is characterized in that actuator is provided for allowing forcing driving wheel to move under the situation of primary importance as the described injection device of claim 90.

92. as the described injection device of claim 91, it is characterized in that this actuator links to each other with driving wheel, be used for forcing driving wheel in primary importance, to make guide rail along forward direction motion.

93., it is characterized in that this actuator is one second to take turns or comprise that second takes turns as the described injection device of claim 90.

94., it is characterized in that this actuator is a control knob as the described injection device of claim 90.

95., it is characterized in that the connection between button and driving wheel comprises cam face as the described injection device of claim 94.

96. as the described injection device of claim 95, it is characterized in that this button can be round the rotation of the push button shaft on the housing, cam face is a curved surface, this curved surface is the center basically with the push button shaft.

97., it is characterized in that between actuator and guide rail, changing gear ratio as the described injection device of claim 90.

98., it is characterized in that arbitrary feature of claim 1-57 as the described injection device of claim 88.

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