The oxter compositions that the purpose of this invention is to provide the shortcoming that has overcome the prior art preparation.
Another object of the present invention provides the oxter unguentum that reduces the syneresis level, and therefore avoids product seepage from packing.
These purposes of the present invention and other purpose can become clearly after having examined appended summary, detailed description and embodiment.
According to a first aspect of the invention, provide the fluid composition of oxter treatment, said composition comprises:
The oxter active substance that (I) exists with the effective dose that suppresses abnormal smells from the patient or minimizing perspiration;
(ⅱ) 0.1-30%'s (weight) crosslinked non--emulsifying silicone elastomer;
(ⅲ) volatile siloxane of 10-80% (weight).
According to another aspect of the present invention, provide the composite ointment of oxter treatment, this unguentum comprises:
Oxter deodorization/hidroschesis active matter matter that (I) exists with the effective dose that suppresses abnormal smells from the patient or minimizing perspiration;
(ⅱ) crosslinked non--emulsifying silicone elastomer is hindered by the crosslinked or portion of 0.1-50% (weight);
(ⅲ) volatile siloxane of 10-80% (weight).
According to a further aspect of the invention, provide to be fit to the local no aqueous fluid hidroschesis suspension composition that uses of application on human skin, said composition comprises:
ⅰ. the hidroschesis astringent of effective dose;
The ⅱ volatile siloxane; With
ⅲ crosslinked or partial cross-linked non--the emulsifying silicone elastomer.
When said composition was suspension, the present invention more specifically provided and is fit to the local fluid hidroschesis suspension composition that uses of application on human skin, and said composition comprises:
ⅰ. account for the hidroschesis astringent of the 5-25% (weight) of total composition;
ⅱ. account for linearity or the ring-type volatile siloxane of the 20-90% (weight) of total composition;
Dimethicone/vinyl dimethicone crosspolymers elastomer thickening agent/suspending agent of ⅲ .0.1-20% (weight) and
ⅳ. shelter oil.
In one embodiment of the invention, provide the aerosol antiperspirant composition, it is characterized in that it comprises the above-mentioned suspension composition of 7-60% and the propellant of 40-93%.
We find by mix can be improved super drying (ultradry) deodorization/hidroschesis unguentum of character of crosslinked or partial cross-linked non--emulsifying silicone elastomer in volatile siloxane at present.An its main advantage for when described elastomer in volatile siloxane (as Cyclomethicone) during swelling, the compositions of generation does not cause syneresis (syneresis generally causes leakage problems).And elastomer can make the Cyclomethicone thickening, has therefore removed causing the needs of other thickening agent that usefulness reduces.Generally speaking, the unguentum product of generation also is better than the commodity product aspect sensation.Coating also is smooth and exsiccant.
Preferred described crosslinked siloxane elastomer makes the vinylsiloxane fluid form through hydrosilylation (hydrolisation) by hydrogen siloxane or MQ hydride fluid.
When described fluid composition was the unguentum form, the taper injection value that described unguentum is fit to was 2mm-36mm.As the oxter of the present invention of unguentum with the general taper injection of compositions value be 2mm-36mm, preferred 10mm-36mm, more preferably 10mm-25mm, be suitably for 12-20mm (measuring) most according to Standard Test Method for Cone Preparation of petrolatum (ASTMD 937).
The first element according to compositions of the present invention is deodorizer and/or hidroschesis active matter matter.The convergence salt that more preferably has deodorization and hidroschesis character.Suitable astringent is the inorganic or organic salt of aluminum, zirconium, zinc and their mixture.The mixture that comprises aluminium halogenide, aluminum hydroxyhalide, zirconyl oxyhalogenation thing, zirconyl hydroxyhalide and these salt as the salt of astringent or astringent coordination compound composition.
Specifically, normally used antisudorific salt comprises the inorganic or organic salt of aluminum and zirconium and their mixture.Particularly preferred is aluminum/zirconates, aluminum zirconates and their mixture of aluminum halide, hydroxyhalides.Particularly preferred hidroschesis salt comprises activatory AACH chemical compound, sees described in the EP 6739 (Unilever NV etc.).EP 28853 has also described other hidroschesis active matter matter.The content that is incorporated herein two applications is for referencial use.
The aluminum salt of this type comprises that aluminum chloride and general formula are Al2(OH)xQy-XH2The hydroxyhalides of O, wherein Q is chlorine, bromine or iodine, and wherein x is 2-5 and x+y=6, and x and y needn't be integer, and X is about 1-6.
Operable zirconium compounds can be represented with following empirical formula: ZnO (OH)2-NzBz, wherein z is about 0.9-2 and needn't be integer, and n is the quantivalence of B, and 2-nz is more than or equal to 0, and B is selected from halo acid group, nitrate anion, sulfamic acid root, sulfate radical and their mixture.If alkaline aluminium compound is appreciated that aforesaid general formula can simplify greatly, and is used to represent and comprises with various amounts and water coordination and/or bonded chemical compound and polymer, mixture and above-mentioned coordination compound.In fact the zirconium hydroxy salt represents a series of chemical compounds with various hydroxy number, in the per molecule number of hydroxyl about 1.1 to changing between being a bit larger tham 0.
It is known in the art using the hidroschesis coordination compound of a few types of above-mentioned convergence salt.The for example coordination compound of glycine of aluminum, zirconium and aminoacid is for example disclosed in U.S. patent 3792068 (Luedders etc.).The coordination compound of reporting in this patent is known as ZAG with similar structure.The ratio of Al in the ZAG coordination compound: Zr is generally about 1.67-12.5, metal: the ratio of Cl is about 0.73-1.93.The aluminium compound formula empirical formula of preferred for preparation ZAG type coordination compound is Al2(OH)5Cl.2H2The alkali formula aluminum chloride of O.The zirconium compounds of preferred for preparation ZAG type coordination compound is formula ZrO (OH) Cl.3H that sees service2The zirconyl hydroxyhalide of O and empirical formula are ZrO (OH)2-aCl2.nH2The zirconyl hydroxyhalide of O, wherein a is 1.5-1.87, n is about 1-7.The aminoacid of preferred for preparation ZAG-type coordination compound is formula CH2(NH2) glycine of COOH.Special preferred particle size is the spherical ZAG of 1-100 μ m.
The deodorant activities amount of substance can be 0.1-70%.When described active substance was convergence salt, its amount can be about 15%-60% (weight) (not comprising glycine, glycinate or other complexant) of anhydrous metal salt.
Deodorant activities material according to the present invention also comprises not as the antisudorific material.Deodorizer should be able to kill or stop the microbial growth that produces abnormal flavour or promote that the body oil decomposition is the odiferous fatty acid.Most of material is short chain monocarbon alcohol, polyhydric alcohol, triclosan, triclorban, chlohexidine (chlorhexedine) and the part aromatic oil that is known as deo spice (as No. 4278658, a U.S. patent, Hopper etc.) in the organic anti-bacterial material.The organic anti-bacterial amount of substance is 0.1-1%, preferred 0.2-0.5% (weight).The inorganic antibacterial material also can be used as the deodorant activities material.These materials comprise zinc oxide, zinc hydroxide, zinc carbonate, hydroxy benzenesulfonic acid zinc, ricinoleic acid zinc, magnesium oxide, magnesium hydroxide, magnesium carbonate, sodium bicarbonate, lanthana, lanthanum hydroxide, lanthanum carbonate and their combination.
Crosslinked non--the emulsifying silicone elastomer is second key element of the present invention.Their number-average molecular weight surpasses 10000, preferably surpasses 1000000, and the best is 10000-20000000.Term " non--emulsifying " is defined as the siloxanes that does not have polyoxyalkylene unit.Described elastomeric illustrative example is crosslinked stearyl methyl-dimethylsiloxane copolymer of CTFA by name; can be by Grant Industries; Inc., Elmwood Park, New Jersey obtain Gransil SR-CYC by name (the active elastomer of 25-35%).The also elastomer that can obtain being correlated with by General Electric Company.
Described silicone elastomer is crosslinked or partial cross-linked, entanglement viscoelasticity copolymer networks, and it is catalytic by Pt, be known as hydride siloxane fluid or the fluidic hydrosilylation prepared in reaction of the fluidic vinylsiloxane of high side chain MQ hydride.The spatial chemistry of the cross-linking agent of vinylsiloxane fluid and silane and the control of type can be controlled the character of this solidified network.Can in reaction medium, introduce other vinyl reactant for example the vinyl alkene with this siloxane network of further modification.The selection of reaction dissolvent also is a method of modification reaction gelling properties, obtains different character, for example dermal sensation because can add certain amount (being easy to control) in polymer network.The mean molecule quantity of silicone elastomer is 10000-20000000.
Elastomeric amount is 0.1-30%, the best 1-15% of being, most preferably is 3-10% (weight).
The three elements that add in the present composition are volatile siloxane.The amount that this material exists is 10-80%, be preferably 10-60%, bestly be 30-50% (important).
Term " volatility " refers to that those can detect the material of pressure under usual conditions.The volatility polysiloxane can be cyclic or linear as used herein.Preferred annular siloxane comprises and contains about 9 silicon atoms of the 3-that has an appointment, preferably about 3-7 silicon atom, and 4-5 silicon atom more preferably from about generally is known as the polydimethylsiloxane of Cyclomethicone.Preferred linear silicone oils comprises the polydimethylsiloxane that contains about 9 silicon atoms of the 3-that has an appointment.Generally viscosity is less than 5 centistokes in the time of 25 ℃ for linear volatile siloxane, and the viscosity of annular material is preferably the scope of 0.1-8 centistoke less than about 10 centistokes.The example that is used for silicone oil of the present invention comprises: DowCorning 344, Dow Corning 345 and Dow Corning 200 (being produced by Dow CorningCorporation); Siloxanes 7207 and siloxanes 7158 (producing) by Union CarbideCorporation; SF 1202 (producing) by General Electric.
Major advantage of the present invention for when described elastomer in volatile siloxane (as Cyclomethicone) during swelling, the material of generation (after this referring to " gel ") can prevent generally to cause the syneresis of leakage problems.Therefore and described elastomer can make the Cyclomethicone thickening, eliminates or part is eliminated other the demand of thickening agent that may reduce usefulness.The unguentum that produces also is better than other known product aspect sensation.Coating also is smooth and exsiccant.
Generally speaking, by using the preferred siloxanes fluids of oil, for example cyclohexyl methyl siloxanes and/or dimethyl siloxane make crosslinking silicone converging network swelling form gel, and the characteristic of gel depends on crosslinked degree.The gel that produces can not weakened by general shearing (for example at 2000rpm), heating or the friction on skin, and contains 0.1-50% crosslinking silicone converging network, i.e. elastomer.
The illustrative example of gel is Cyclomethicone poly dimethyl silicone/vinyl poly dimethyl silicone cross linked polymer of CTFA by name, this polymer contains the 0.1-50% that has an appointment, preferred 1-20%, the more preferably poly dimethyl silicone of 1%-8%/vinyl poly dimethyl silicone cross linked polymer (elastomer), is known as KSG-15 ex Shin-Etsu.Crosslinked siloxane elastomer that other is suitable and gel can be obtained by Witco Corporation, Dow Corning and General Electric.
Compositions of the present invention also can contain powdered filler.The illustrative example of such material is starch, Pulvis Talci, the silica gel of being fuming (fumed silica) (as derive from Cabot Corporation Cab-O-Sil), meticulous silica gel (as sodium silicate), sodium bicarbonate, Magnesiumaluminumsilicate, clay and their mixture.Be corn starch and modified starch most preferably and effectively, starch octene agent succinic acid aluminum particularly can be at trade (brand) name Dry FloDown by National Starch ﹠amp; ChemicalCompany obtains.
The amount of powdered filler is 1-40%, preferred 10-35%, the best 15-30% (weight) of being.
Also can comprise inert particle in the cosmetic unguentum of the present invention.The illustrative example of this type of material comprises polyolefin (for example polyethylene and polypropylene) and nylon.Most preferred is spherical or aspheric polyethylene powders.These amount of substances are in the 0.1-20% scope, be preferably 1-10% (weight).
Choose wantonly in the cosmetic unguentum of the present invention and comprise non-volatile C12-C40Hydrocarbon.This amount of substance is 1-40%, preferred 5-25%, the best 10-20% (weight) of being.
The viscosity of non--volatile hydrocarbon is at least 10cs, preferably is 10-100000cs in the time of 25 ℃ in the time of 25 ℃.C12-C40, preferred C20-C40Hydrocarbon can be saturated or unsaturated.Example comprises dodecane, tridecane, the tetradecane, pentadecane, hexadecane, heptadecane, octadecane, nonadecane, eicosane (ecosane), heneicosane, docosane, tricosane, lignocerane, pentacosane, the isomer of these chemical compounds and their mixture.Most preferably the trade mark that is obtained by EthylCorporation is the poly decene of Ethylflo.
Polyolefin is suitable hydrocarbon polymer, and preferably at room temperature (promptly 21 ℃) are the polymer of liquid.Polyolefin in the also special preferred composition has low relatively viscosity.The viscosity of preferred polyolefm screening agent is lower than about 40cSt, more preferably is lower than about 30cSt in the time of 40 ℃ in the time of 40 ℃.
Preferred described polyolefin contains polyalphaolefin.The polyalphaolefin that is preferred in the present composition is a poly decene, and for example the Silkflo of poly decene scope is produced by Albermarle Corporation.Other the preferred polyolefin that is used for the present composition comprises polybutene, can under trade name Panalene L14E, obtain by Amoco, and polyisobutylene, can under trade name Permethyl, obtain by Prespere.
Therefore, the preferred polyolefin monomer chain length degree that is used for the present composition is a 3-15 carbon atom.The preferred various commercial polyolefinic mixture that obtains can contain the mixing of various polymer, comprises dimer, trimer etc.The preferred material that is used for the present composition comprises Silkflo 362NF, Silkflo 364NF and the Silkflo366NF that is obtained by Albermarle Corporation.
When being used for compositions of the present invention, described polyolefin can help described compositions to have surprising good feel characteristic, comprise the no greasy in coating back, when described compositions can improve the degree of sheltering to any bleaching (being caused by the hidroschesis salt in the compositions) during for antiperspirant composition.
Use polyolefinic advantage the usefulness of hidroschesis active salt in the compositions not to be had any interference largely for them.
Can shelter oil as the non--volatility of lubricant also can right and wrong-volatile siloxane.This non--volatile siloxane can be poly-alkylsiloxane, poly-alkaryl siloxanes or polyether siloxane copolymer.Preferred poly-alkylsiloxane range of viscosities in the time of 25 ℃ is 10-100000mm2s-1(cSt).This type of siloxanes can be obtained with DowCorning 200 series by Dow Corning Corporation.
Suitable poly-alkaryl siloxanes is 15-65mm for viscosity in the time of 25 ℃2s-1(cSt) PSI.These siloxanes can obtain by Dow Corning 556 fluids.Suitable polyether silicone is about 1200-1500mm for viscosity in the time of 25 ℃2s-1(cSt) dimethyl polyoxyalkylene ether copolymer, for example polysiloxanes glycol ether copolymer.
Oxter of the present invention with the lubricant that also can comprise other in the compositions for example non--volatile siloxane, hydrocarbon or mineral oil.
Also can comprise inert particle in the cosmetic unguentum of the present invention.The illustrative example of this type of material comprises polyolefin (for example polyethylene and polypropylene) and nylon.Most preferred is spherical or aspheric polyethylene powders.These amount of substances are 0.1-20%, be preferably 1-10% (weight).
Also wax can be mixed in the compositions of the present invention.The wax of animal origin comprises Cera Flava, spermaceti, lanoline and Lac.The wax of plant origin comprises carnauba wax, candelilla wax, bayberry wax and sugarcane wax.Other example comprises high and low-melting wax, glue, resin, polymer, starch and elastomer.Dystectic wax comprises insecticide and animal wax, for example Cera Flava and spermaceti; Vegetable wax is Brazil wax, candelilla wax, little carnauba wax, Japan wax, star-spangled banner bark wax, rice bran wax, castor wax and bayberry wax for example; Mineral wax is montan wax, peat wax, (pure) ceresine and ceresine for example; Pertroleum wax is paraffin for example; Synthetic wax is Fischer-Tropsch wax, polyethylene glycol wax for example, the amide waxe of chemical modification chloroflo and replacement.The example of low melt wax comprises fatty acid, aliphatic alcohol, fatty acid ester and the fatty acid amide of 3-30 carbon atom.Preferred especially low-melting wax comprises stearyl alcohol, cetyl alcohol, the pure and mild Palmic acid of myristyl.
The amount of described wax is 0.5-30% (weight).
The taper injection value that most preferably is the fluid composition of the present invention of unguentum is 2-36mm, preferred 10mm-25mm, be suitably for 12-20mm (measuring according to Standard Test Method forCone Preparation of petrolatum (ASTM D 937)) most.
When described compositions was no water slurry, compositions of the present invention also can comprise other the general composition in the antiperspirant composition.Ball-type preparation particularly for example, the amount that lubricant fluid exists are 0-25% (weight), preferred 1-23%, more preferably 5-20%.Suitable lubricant is dipropylene glycol methyl ether, non--the volatile siloxane fluid material, hydrocarbon for example poly decene or mineral oil.
Compositions of the present invention also can be the form of aerosol concentrated solution, it can with propellant for example independent or blended iso-butane, butane, propane or pentane dilution.When using in aerosol, the amount of used composition can be adjusted with the propellant dilution of following scope (percentage by weight) usually:
Hidroschesis active matter matter as many as 20%, preferred 1-10%, more preferably 5-10% and preferred especially 8-10%;
Volatile siloxane is 0.5-40%, preferred 10-20%;
When described antiperspirant was aerosol form, zirconium compounds was not suitable actives matter usually.
The following example will illustrate embodiment of the present invention more comprehensively, and percentage ratios all except that specializing all are weight percentage.
Embodiment 1
Preparation is listed in the preparation of table 1 to estimate its usefulness and seepage tendency.
Table 1
Preparation
| Composition | Weight % |
| Cyclomethicone | 39.2 |
| Gransil?SR-CYC | 20.0 |
| Poly decene 364 | 14.8 |
| AZAG salt | 26.0 |
Use two kinds of test methods to estimate seepage.First kind of ply of paper analysis method for improvement, second kind is finished product/packaging test.
Analyse in the test at ply of paper, a series of 10cc beakers are packed into test-manufactured thing.Then they are placed the chromatography development chamber.Because they can have two slotted lines by commerce acquisition and each tangent plane, replace the ply of paper of standard to analyse with fragrant blotting paper slip.Described blotting paper is immersed in the product to article one line.They were placed development chamber at least one hour.Then according to the range determination seepage in article one line and liquid forward position.
For carrying out described product/packaging test, product is packed in the standard propelling/resistance hidroschesis Bistributor package.Then at this product of package top surface extruding.Carefully avoid alleviating accumulative pressure in allotter.Described top is restored to the original state, allotter is placed a period of time.Observe seepage then.
Embodiment 2-8
The illustrative example of preparation of the present invention is the preparation that is recorded in the table II.
The table II
| Composition | Embodiment (weight %) |
| ???2 | ???3 | ????4 | ????5 | ????6 | ???7 | ????8 |
| Cyclomethicone | ??29.7 | ??29.7 | ???29.7 | ???29.7 | ??68.0 | ??50.0 | ???50.0 |
| Gransil?SR-CYC | ??13.5 | ??13.5 | ???13.5 | ???13.5 | ??6.0 | ??2.0 | ???1.0 |
| Poly decene 364 | ??10.8 | ??10.8 | ???10.8 | ???10.8 | ??-- | ??10.8 | ???10.8 |
| AZAG | ??26.0 | ??26.0 | ???26.0 | ???-- | ??26.0 | ??26.0 | ???26.0 |
| Triclosan | ??-- | ??-- | ???-- | ???2.0 | ??-- | ??-- | ???-- |
| Corn starch | ??20.0 | ??00 | ???18.5 | ???20.0 | ??-- | ??11.2 | ???-- |
| Pulvis Talci | ??-- | ??20.0 | ???-- | ???20.0 | ??-- | ??-- | ???10.2 |
| The silica gel of being fuming | ??-- | ??-- | ???1.5 | ???4.0 | ??-- | ??-- | ???1.0 |
Embodiment 9
Comparative examples
Preparation has the siloxanes cerul hidroschesis paste of following prescription: composition function %wt volatile siloxane carrier 43.0Ethylflo 364 (poly decenes) precipitation screening agent 14.0 talcum powder help dry skin 6.0AZAG active material 24.0 spices 1.0Bentone 38 suspending agents 1.0 siloxane wax ex GE 6.0 castor wax MP 80 structural agents 5.0
Embodiment 10
Preparation has the of the present invention anhydrous hidroschesis unguentum of following prescription: composition function %wtAZAG (powder) antiperspirant 24.0 castor wax structural agents 5.0 silicone gel Jiao Ningji ﹠amp; 49.0JK301, (C30+) ex GE deposition screening agent bentonite structural agent 1.0 non--volatile hydrocarbon deposition screening agents 14.0, (Albemarle Ethylflo 364NF) Pulvis Talci, (Suprafino) help dry skin 6.0 spice 1.0 whole elastomer % 2.45%
By described wax and liquid heat to 85 ℃ being sheared then the preparation unguentum.When shearing, add silicone gel, then add described powder and spice.Continue to be trimmed to homogeneous.The product that produces is condensed unguentum.
Embodiment 11
10 described preparations have the anhydrous hidroschesis unguentum of following combination: composition %wtAZAG (powder) 24.0 castor wax MP 80 5.0GE JK 301 gels 33.0 bentonites 1.0 volatile siloxane DC344 16.0Ethylflo 364NF 14.0 Pulvis Talci 6.0 spice 1.0 whole elastomer % 1.68% according to embodiment
The product that produces is the unguentum with unusual dry sensation.
Embodiment 12 composition %wtAZAG (powder) 24.0GE silicone gel 20.0JK301 bentonites 1.0 volatile siloxane DC344 34.0Silkflo 364 NF 14.0 Pulvis Talci 6.0 spice 1.0 whole elastomer % 1.0%
The product that produces has the diluent denseness of dry sensation.
Rheology
Detect the rheology of embodiment 10,11 and 12 preparations, with the proof stability that said composition is processed at various temperatures when with the comparative examples compositions comparison of siloxanes cerul.
Use Carri-Med Controlled Stress Rheometer CSL 100 instruments.Use on the cup and be furnished with the weathercock/cup measuring system of Intranet to prevent the wall landing.Except that specializing, test is generally carried out at 25 ℃.The equiulbrium flow dynamic test carries out to obtain the flowing property accurately of sample with fresh sample.Before measurement, make described sample in a fixed temperature (25 ℃) balance 1 hour to guarantee no thermograde.
The data that produce cause viscosity number (Pa.s) and sample under low-shearing force to cause the balance of ruining between failed point.The balance viscosity value is low more, and described sample is unstable more.
The result
As shown in drawings, with shown in the comparative examples of cerul compare, the pressure that produces with the sample of described silicone elastomer preparation improves.
Stability
Embodiment 11 and 12 preparations are compared with the comparative examples stability of formulation with the stability when the high temperature in time.
All compositionss all are packaged in the identical Bistributor package.
All preparations all stood to shear 2 minutes under room temperature.Thinning and the demonstration volatile siloxane seepage sign of comparative examples compositions.
Yet, embodiment 10 and 11 compositions non-volatility siloxanes seepage sign.
Also comparative examples and embodiment 10 and 11 were placed for 6 weeks in 40 ℃.The compositions display siloxanes seepage of comparative examples.And compositions ne-leakage of the present invention takes place.
Embodiment 13
Comparative examples:
Preparation has the hidroschesis ball-type preparation of following prescription:
| Composition | Function | ％wt |
| Volatile siloxane (DC 344) | Carrier | 59.0 |
| AZAG | Active substance | 25.0 |
| Bentonite | Suspending agent | 3.0 |
| Polyethylene | The dermal sensation regulator | 7.0 |
| The myristyl isopropyl ester | Lubricant | 3.0 |
| Allyl carbonate | Suspending agent | 1.0 |
| Aerosil?200 | The suspension thickening agent | 0.3 |
| DC?200/300 | Lubricant | 0.7 |
| Spice | | 1.0 |
The ball-type antiperspirant composition that also prepares the following example of the present invention:
The table III
| Embodiment 14 | Embodiment 15 | Embodiment 16 | Embodiment 17 | Embodiment 18 | Embodiment 19 |
| Volatile siloxane (DC344) | ????66.00 | ????64.00 | ????62.00 | ????60.00 | ????23.50 | ????23.50 |
| GE silicone elastomer gel JK513 | ????6.00 | ????8.00 | ????10.00 | ????12.00 | ????37.50 | ?????-- |
| GE silicone elastomer gel JK501 | ????-- | ????-- | ?????-- | ?????-- | ?????-- | ????37.50 |
| AZAG | ????24.00 | ????24.00 | ????24.00 | ????24.00 | ????24.00 | ????24.00 |
| Bentonite | ????3.00 | ????3.00 | ????3.00 | ????3.00 | ????-- | ????-- |
| Spice | ????1.00 | ????1.00 | ????1.00 | ????1.00 | ????1.00 | ????1.00 |
| Pulvis Talci | ????-- | ????-- | ????-- | ????-- | ????-- | ????-- |
| Ethy1flo?364NF | ????-- | ????-- | ????-- | ????-- | ????14.00 | ????14.00 |
| ????100.00 | ????100.00 | ????100.00 | ????100.00 | ????100.00 | ????100.00 |
| Proof resilience body % | ????0.3 | ????0.4 | ????0.5 | ????0.6 | ????1.875 | ????1.875 |
If the selection partitioning agent is an aerosol, so the present composition is combined with the aerosol propellant.
The general factor decision that the amount of propellant gas is known by the aerosol field.Compositions shown in the front is a concentrated solution, contain 7%-60%, the preferred total aerosol combination of 20%-40%, and propellant is the 40%-93% of composition weight, preferred 60%-80%.
When being used for aerosol combination, do not need described bentonite suspending agent.It is effective especially that we find to contain the aerosol combination of 20% gel.The aerosol that produces has required drying sensation.Generally speaking, having as many as 0.25% elastomeric aerosol combination is effectively, and the elastomer of 0.125% concentration is stable especially, has seldom or do not have segregation phenomenon after 3 days.
Stability/segregation phenomenon research
The stalling characteristic of check comparative examples and embodiment 14-19 preparation.The results are shown in the table IV.
After 1,2,3,5 and 6 day, prepare compositions and check segregation phenomenon.As shown, and only compare with the comparative examples of aeroge thickening, compositions segregation phenomenon of the present invention significantly reduces.
Table IV-viscosity/segregation phenomenon data
| Comparative examples | Embodiment 14 | Embodiment 15 | Embodiment 16 | Embodiment 17 | Embodiment 18 | Embodiment 19 |
| Initial viscosity | | | | | | | |
| TBAR?B?@ 10RPM | ???600cps | ???1000cps | ???3900cps | ????6000cps | ????4000cps | ???6000cps | ????5400cps |
| TBAR?B?@ 50RPM | ???180cp8 | ???480cps | ???880cps | ????1360cps | ????1040cps | ???1720cps | ????1360cps |
| My god/segregation phenomenon (mm) | | | | | | | |
| 1 | ?????4 | ?????1 | ??????1 | ??????1 | ??????3 | ?????0 | ?????-- |
| 2 | ?????7 | ?????3 | ??????3 | ??????2 | ??????3 | ?????0.5 | ?????-- |
| 3 | ?????-- | ?????4 | ??????-- | ??????-- | ??????-- | ?????-- | ?????-- |
| 5 | ?????8 | ?????-- | ??????4 | ??????2 | ??????4 | ?????0.5 | ?????-- |
| 6 | ?????-- | ?????5 | ??????-- | ??????-- | ??????-- | ?????-- | ?????-- |