Disclosure of Invention
The invention provides a degradable nested anastomosis device.
Specifically, the invention is realized by the following technical scheme:
The embodiment of the invention provides a degradable nested anastomosis device, which comprises an inner cylinder and an outer sleeve, wherein a radially protruding ring ridge is arranged outside the inner cylinder, a lock seat is arranged on the side, close to the rear end, of the ring ridge, a first wall section is formed between the front end and the ring ridge, a second wall section is formed between the ring ridge and the lock seat, a base sleeve and an elastic claw extending from the base sleeve to the rear end are arranged outside the inner cylinder, a tapered end is arranged at the rear end of the elastic claw, a closing-in end of the base sleeve is arranged at the front end of the elastic claw, the inner wall of the outer sleeve, the elastic claw and the tapered end are matched with the front end of the inner cylinder, the first wall section, the second wall section and the lock seat respectively, so that the outer sleeve can be nested at a nesting position outside the inner cylinder from the front end to the rear end of the inner cylinder, the closing-in is enabled to be abutted against the front end of the inner cylinder axially, the inner sleeve is enabled to be internally attached to the outline of the first wall section of the inner cylinder, a cavity is formed between the inner sleeve and the inner cylinder and the elastic claw can rotate relative to the inner cylinder at the nesting position, and the outer sleeve can be locked through the tapered end and the lock seat.
In some embodiments, the annular ridge is disposed along a continuous extension on the exterior of the inner barrel.
In some embodiments, the lock base includes a lock base body extending in a circumferential direction and a lock base hook extending from an end of the lock base body toward a rear end, and the lock head includes a lock head body extending in the circumferential direction and a lock head hook extending from the end of the lock head body toward a front end.
In some embodiments, the resilient pawl is configured as a pawl base and a pawl head, the cavity being formed between the interior of the pawl base and the second wall segment, the interior of the locking head being clamped against the exterior of the second wall segment under the action of the resilient restoring force.
In some embodiments, the first wall segment and the circumferential ridge have an arcuate transition profile therebetween.
In some embodiments, the ridge and the second wall segment form an acute angled transition profile therebetween.
In some embodiments, the inner barrel and/or the outer sleeve are externally provided with clamping structures for tool clamping.
In some embodiments, the inner barrel and/or the outer sleeve are made of magnesium-based alloys.
In some embodiments, the inner barrel and/or outer sleeve surface is provided with a coating comprising RGB peptides or heparin.
According to the embodiment of the invention, the inner part of the base sleeve is attached to the contour of the first wall section, so that a blood vessel can be compressed in a large area between the inner part of the base sleeve and the first wall section, the anastomotic tightness between two blood vessel broken ends is ensured, the two blood vessel broken ends can be fixed by local expansion through the radially-protruding annular ridge outside the inner cylinder, the vascular fixing firmness is improved, the fold area of the blood vessel broken ends can be accommodated through the cavity formed between the inner part of the elastic claw and the second wall section of the inner cylinder, the anastomotic loosening caused by the relative displacement between the blood vessel broken ends caused by fold extrusion is avoided, and the lock seat, the lock head and the lock seat can be mutually locked only by mutually rotating the outer sleeve and the inner cylinder and simultaneously act with the lock seat, so that the inner cylinder and the outer sleeve are locked in a nested state, and the whole anastomotic operation is simple and convenient. Meanwhile, the nested anastomat made of the degradable material can be slowly degraded in the body without taking out by a secondary operation.
It is to be understood that both the foregoing general description and the following detailed description are exemplary and explanatory only and are not restrictive of the application as claimed.
Drawings
The accompanying drawings, which are incorporated in and constitute a part of this specification, illustrate embodiments consistent with the application and together with the description, serve to explain the principles of the application.
FIG. 1 is a schematic view of a detachable state of a degradable nested anastomosis device according to an embodiment of the present invention;
FIG. 2 is a schematic illustration of an anastomosis state of a degradable nested anastomosis device in accordance with an embodiment of the present invention;
FIG. 3 is a schematic illustration of a jacket in an embodiment of the present invention;
FIG. 4 is a schematic view of an inner barrel in an embodiment of the invention;
FIG. 5 is a cross-sectional view of a degradable nested anastomosis device in accordance with one embodiment of the present invention;
Fig. 6 is a partial enlarged view at a in fig. 5.
Reference numerals:
10 parts of inner cylinder, 11 parts of annular ridge, 12 parts of first wall section, 13 parts of second wall section, 14 parts of lock seat, 141 parts of lock seat body, 142 parts of lock seat hook, 20 parts of outer sleeve, 21 parts of base sleeve, 211 parts of closing-in, 22 parts of elastic claw, 221 parts of claw root, 222 parts of claw head, 23 parts of lock head, 231 parts of lock head body, 232 parts of lock head hook and 30 parts of cavity.
Detailed Description
The invention will now be discussed with reference to several embodiments. It should be understood that these embodiments are discussed only in order to enable a person of ordinary skill in the art to better understand and thus practice the invention, and are not meant to imply any limitation on the scope of the invention.
As used herein, the terms "comprises," comprising, "and variations thereof are to be construed as open-ended terms that mean" including, but not limited to, "an embodiment, and" one embodiment "are to be interpreted to mean" at least one embodiment, "another embodiment" is to be interpreted to mean "at least one other embodiment," the terms "first," "second," and the like, may refer to different or the same objects, and the term "arrangement" is not limited to direct or indirect connections, nor to a particular manner of connection. Other explicit and implicit definitions are also possible below.
Some specific values or ranges of values may be referred to in the following description. It should be understood that these numerical values and numerical ranges are merely exemplary, which may be advantageous to put the inventive concept into practice. However, the description of these examples is not intended to limit the scope of the invention in any way. These values or ranges of values may be set otherwise, depending on the particular application and requirements.
As described above, prior art nested staplers are structurally limited and do not provide higher anastomosis strength on degradable stapler products. The above-described problems are at least partially solved by a degradable nested anastomosis device as set forth in embodiments of the present invention. The structure and operation of the degradable nested anastomosis device according to an exemplary embodiment of the present invention will be described below with reference to fig. 1 to 6. As shown in fig. 1 to 6, the degradable nested anastomotic device according to the embodiment of the present invention is composed of an inner tube 10 and an outer tube 20 which are nested with each other, and at least one of the outer tube 20 and the inner tube 10 may be provided with a clamping structure for clamping a tool.
For clarity of description of the structure and operation of the degradable nested anastomosis device of the present embodiment, as shown in fig. 5, the end of the sheath 20 where the neck 211 is located and the end of the first wall section 12 of the inner barrel 10 where the neck is located are defined as the "front end", and the other end opposite to the "front end" is defined as the "rear end".
The inner tube 10 is generally cylindrical, and is hollow in the interior thereof, and one blood vessel is passed through the hollow. The outer contour of the inner cylinder 10 is formed with a first wall section 12, a ring ridge 11 and a second wall section 13, the positions of the first wall section 12, the ring ridge 11 and the second wall section 13 are sequentially arranged from the front end to the rear end, the first wall section 12 and the ring ridge 11 are in transition, and the ring ridge 11 and the second wall section 13 are in transition.
The annular ridge 11 protrudes radially from the outside of the inner barrel 10, and the protruding part has larger radial dimension and larger local pressure, so that the blood vessel can be firmly supported at the annular ridge 11, and no displacement occurs between the blood vessel and the inner barrel 10. In one embodiment, as shown in FIGS. 1-4, the circumferential ridge 11 extends continuously along the circumference of the inner barrel 10, enabling the circumferential ridge 11 to provide a stent effect on the vessel at every position over a 360 degree range. In another embodiment, the annular ridge 11 may be configured to extend intermittently along the circumference of the inner barrel 10.
The ring ridge 11 is connected at the front end side to the first wall section 12. In one embodiment, the transition profile between the ring ridge 11 and the first wall section 12 is arcuate, as shown in FIGS. 5 and 6, which may be concave, such that the heads 222 of the resilient fingers 22 are guided by the arcuate transition profile to be smoothly spread over the ring ridge 11 during the forward pushing of the outer sleeve 20 to the exterior of the inner sleeve 10.
The ring ridge 11 is connected at the rear end side to the second wall section 13. In one embodiment, the transition profile between the ridge 11 and the second wall section 13 is inclined at an acute angle, as shown in fig. 5 and 6, and the angle between the wall of the ridge 11 at the rear end and the second wall section 13 is smaller than 90 degrees, so that the blood vessel wall can be attached to the wall inclined at an acute angle towards the front end, that is, the blood vessel wall can be ensured to be hooked more firmly at the ridge 11.
The outer jacket 20 integrally includes an annular base jacket 21 and elastic claws 22, the elastic claws 22 extending from the base jacket 21 toward the rear end, and the number of the elastic claws 22 may be 2, 3,4, or more, for example. The front end of the outer sleeve 20 is provided with a closing-up 211 with a reduced radial dimension, and the closing-up 211 can be abutted against the front end of the inner cylinder 10, so that the front end of the inner cylinder 10 is prevented from penetrating out of the closing-up 211 of the outer sleeve 20.
The inside of the base sleeve 21 is set to be attached to the outline of the first wall section 12 of the inner cylinder 10, when the blood vessel wall is clamped by the base sleeve 21 and the first wall section 12, the compression area between the blood vessel wall and the inside of the base sleeve 21 and between the blood vessel wall and the first wall section 12 is greatly increased, so that the tightness of the anastomotic surface of the two blood vessel broken ends is improved.
The elastic claw 22 is provided in a cantilever structure and thus has elasticity, can be spread radially outward by the ridge 11, and is pressed against the second wall section 13 by an elastic restoring force. In one embodiment, the resilient fingers 22 are configured as a finger root 221 and a finger head 222, the finger root 221 being connected to the base sleeve 21, the finger root 221 being internally formed as a radially outwardly arched shape, the arch forming a cavity 30 with the second wall section 13 of the inner barrel 10, such that the cavity 30 accommodates a vessel wall fold of a larger size, and the squeezing force within the fold would be transferred to the vessel wall in the peripheral region if there were no space to accommodate the fold, thereby causing relative displacement of the vessel wall with respect to the inner barrel 10 and the outer sleeve 20.
The outer part of the inner cylinder 10, which is located near the rear end of the second wall section 13, is provided with a lock seat 14, the claw 222 of the outer sleeve 20 is provided with a locking head 23, so that the outer sleeve 20 and the inner cylinder 10 rotate relatively, and the locking head 23 can be matched with the lock seat 14, thereby locking the inner cylinder 10 and the outer sleeve 20 in a nested position.
In one embodiment, the lock base 14 includes a lock base body 141 extending in a circumferential direction and a lock base hook 142 extending from an end of the lock base body 141 toward a rear end, and the lock cylinder 23 includes a lock cylinder body 231 extending in a circumferential direction and a lock cylinder hook 232 extending from an end of the lock cylinder body 231 toward a front end. When the inner cylinder 10 and the outer sleeve 20 relatively rotate, the lock head hooks 232 and the lock seat hooks 142 are used for providing a locking effect of the inner cylinder 10 and the outer sleeve 20 relatively moving along the circumferential direction, and the lock head hooks 232 and the lock seat body 141 and the lock seat hooks 142 and the lock head body 231 are matched for providing a locking effect of the inner cylinder 10 and the outer sleeve 20 relatively moving along the axial direction.
In one embodiment, the inner barrel 10 and the outer sleeve 20 are made of magnesium-based alloy such that the anastomosis device is gradually degraded in the body. For example, mg-1Zn-0.5Mn (wt%) is selected as the magnesium-based alloy, and the degradation rate can reach 0.5-1.0 mm/year. Along with the inner cylinder 10 and the outer sleeve 20 being gradually degraded in the body, the first wall section 12 and the base sleeve 21 can still keep enough large attaching area to ensure tightness between anastomosed blood vessels, meanwhile, the annular ridge 11 can still keep enough large supporting force on the blood vessels to ensure firmness between the blood vessels and anastomosed devices, and the mechanical locking structure has larger wall thickness to ensure that the locking function is not invalid.
In one embodiment, the inner barrel 10 and the outer barrel 20 are provided with a coating containing RGB peptide or heparin on the surfaces thereof, and by surface modification, endothelial cell adhesion can be promoted, and thrombosis can be inhibited.
When the degradable nested anastomotic device of the embodiment of the invention is used, one broken end blood vessel passes through the hollow of the inner cylinder 10 from the rear end and is hooked at the annular ridge 11 from the front end in an everting way, the other broken end blood vessel passes through the outer sleeve 20 from the front end to the rear end and is hooked at the annular ridge 11, and at the moment, the two broken end blood vessels are hooked at the annular ridge 11 at the same time. After that, the outer sleeve 20 is pushed from the front end to the outside of the inner cylinder 10 and continuously pushed to the rear end, the claw heads 222 cross the annular ridge 11 and clamp the blood vessel at the position of the second wall section 13 until the closing-up 211 abuts against the front end of the inner cylinder 10, the outer sleeve 20 is rotated to enable the lock seat 14 and the lock head 23 to be mutually locked, and the blood vessel anastomosis operation is completed, so that the whole operation process is convenient and efficient.
Any references to directions and orientations in the description of the embodiments herein are for convenience only and should not be construed as limiting the scope of the invention in any way. The description of the preferred embodiments will refer to combinations of features, which may be present alone or in combination, and the invention is not particularly limited to the preferred embodiments. The scope of the invention is defined by the claims.
The foregoing description of the preferred embodiments of the invention is not intended to be limiting, but rather is intended to cover all modifications, equivalents, alternatives, and improvements that fall within the spirit and scope of the invention.