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CN119033509B - Artificial aortic valve sinus complex - Google Patents

Artificial aortic valve sinus complex

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Publication number
CN119033509B
CN119033509BCN202411496376.6ACN202411496376ACN119033509BCN 119033509 BCN119033509 BCN 119033509BCN 202411496376 ACN202411496376 ACN 202411496376ACN 119033509 BCN119033509 BCN 119033509B
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leaflet
valve
skirt
lower edge
sinus
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CN119033509A (en
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孙善权
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Beijing Shendi Medical Technology Co ltd
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Beijing Shendi Medical Technology Co ltd
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Abstract

Translated fromChinese

本公开涉及医疗器械技术领域,具体涉及一种人工动脉瓣膜瓣窦复合体,所述人工动脉瓣膜瓣窦复合体包括瓣叶下缘裙边和瓣叶,瓣叶下缘裙边的一面用于与瓣环相贴并与瓣环连接,瓣叶的下缘与瓣叶下缘裙边的另一面连接,用于在瓣叶与窦壁之间形成瓣兜。此该方案降低了对动脉瓣进行置换的操作难度,提高了置换的成功率。

The present disclosure relates to the field of medical device technology, and more specifically, to an artificial aortic valve sinus complex. The artificial aortic valve sinus complex comprises a leaflet lower edge skirt and leaflets. One side of the leaflet lower edge skirt is adapted to abut and connect to the valve annulus, while the leaflet lower edge is coupled to the other side of the leaflet lower edge skirt to form a valve pocket between the leaflet and the sinus wall. This solution reduces the operational difficulty of aortic valve replacement and improves the success rate of replacement.

Description

Artificial valve sinus complex
Technical Field
The present disclosure relates to the technical field of medical devices, and in particular, to a prosthetic valve sinus complex.
Background
Complicated congenital heart diseases such as pulmonary occlusion, severe stenosis of pulmonary artery, etc. often include aortic valve replacement due to lack of connection between right ventricle and pulmonary artery, or extreme stenosis (dysplasia) of pulmonary valve, and aortic valve functional loss caused by congenital aortic valve stenosis and acquired aortic valve lesions in children, and aortic valve replacement. In the related art, a self-body pericardium sheet or a bovine pericardium patch can be cut and sewn to form a prosthetic valve material, so that the prosthetic valve material can be used for replacing an arterial valve in an operation.
However, the applicant found that, because the shape of the above-mentioned artificial artery valve material is relatively simple, in the operation, it is often necessary to firstly cut the artificial artery valve material by a doctor, and then replace the artery valve by using the artificial artery valve obtained by cutting, in this process, it is also necessary to ensure that the shape of the formed valve pocket after replacement is relatively close to that of the valve pocket in the human body, so as to ensure that the opening and closing functions of the artificial artery valve after replacement are all perfect, thereby increasing the operation difficulty of replacing the artery valve and reducing the success rate of replacement.
Disclosure of Invention
To solve the problems in the related art, the embodiments of the present disclosure provide a prosthetic valve sinus complex.
In a first aspect, embodiments of the present disclosure provide a prosthetic valve sinus complex comprising a leaflet lower edge skirt and a leaflet;
One surface of the skirt edge of the lower edge of the valve leaflet is used for being attached to and connected with the valve annulus;
The lower edge of the leaflet is connected to the other side of the leaflet lower edge skirt for forming a leaflet pocket between the leaflet and the sinus wall.
In one embodiment of the present disclosure, an upper rim arm protrudes from the leaflet between an upper rim of the leaflet and a lower rim of the leaflet, an end of the upper rim arm for connection with the sinus wall.
In one embodiment of the present disclosure, the prosthetic valve sinus complex further comprises an upper rim arm skirt, one face of the upper rim arm skirt being connected to an end of the upper rim arm, the other face of the upper rim arm skirt being adapted to be connected to the sinus wall.
In one embodiment of the present disclosure, the leaflet is integrally formed with the leaflet lower edge skirt;
Or the lower edge of the valve leaflet is sewed with the other surface of the skirt edge of the lower edge of the valve leaflet.
In one embodiment of the present disclosure, the leaflet lower edge skirt, and the upper edge arm skirt are integrally formed;
Or the lower edge of the valve leaflet is sewed with the other surface of the lower edge skirt of the valve leaflet, and one surface of the upper edge arm skirt is sewed with the end part of the upper edge arm.
In one embodiment of the present disclosure, the leaflet, leaflet lower edge skirt and upper edge arm skirt are pieces of the same tissue, chemically modified pieces of a heterologous tissue, or patches of an artificial material.
In one embodiment of the present disclosure, the chemically modified xenogeneic tissue sheets include anti-calcified modified animal pericardium and arterial valves.
In one embodiment of the present disclosure, the upper edge of the leaflet is a convex structure that gradually decreases from the middle to both ends.
In one embodiment of the present disclosure, the prosthetic valve sinus complex further comprises a prosthetic sinus wall connected to the leaflet skirt, the prosthetic sinus wall for abutment with the sinus wall.
In one embodiment of the present disclosure, the leaflet lower edge skirt is attached to the artificial sinus wall by a detachable structure.
According to the technical scheme provided by the embodiment of the disclosure, the artificial arterial valve sinus complex comprises a leaflet lower edge skirt and a leaflet, one surface of the leaflet lower edge skirt is used for being attached to an annulus and connected with the annulus, and the lower edge of the leaflet is connected with the other surface of the leaflet lower edge skirt and used for forming a leaflet pocket between the leaflet and the sinus wall. In operation, a doctor only needs to cut the skirt edge of the lower edge of the valve leaflet according to the annular shape of the valve leaflet, then one surface of the skirt edge of the lower edge of the valve leaflet is attached to the annular and connected with the annular, a valve pocket can be formed between the valve leaflet and the sinus wall, the shape of the valve pocket is formed before replacement, the shape of the valve pocket is relatively similar to that of the valve pocket in a human body, and the opening and closing functions of the valve sinus complex of the artificial artery after replacement can be ensured to be perfect.
It is to be understood that both the foregoing general description and the following detailed description are exemplary and explanatory only and are not restrictive of the disclosure.
Drawings
Other features, objects and advantages of the present disclosure will become more apparent from the following detailed description of non-limiting embodiments, taken in conjunction with the accompanying drawings. In the drawings:
fig. 1 illustrates an elevation view of a prosthetic valve sinus complex according to an embodiment of the present disclosure.
Fig. 2 illustrates a top view of a prosthetic valve sinus complex according to an embodiment of the present disclosure.
Fig. 3 illustrates a longitudinal cross-sectional view of a prosthetic valve sinus complex according to an embodiment of the present disclosure.
Fig. 4 illustrates an elevation view of a prosthetic valve sinus complex according to an embodiment of the present disclosure.
Fig. 5 illustrates a top view of a prosthetic valve sinus complex according to an embodiment of the present disclosure.
Fig. 6 illustrates a longitudinal cross-sectional view of a prosthetic valve sinus complex according to an embodiment of the present disclosure.
Detailed Description
Hereinafter, exemplary embodiments of the present disclosure will be described in detail with reference to the accompanying drawings so that those skilled in the art can easily implement them. In addition, for the sake of clarity, portions irrelevant to description of the exemplary embodiments are omitted in the drawings.
In this disclosure, it should be understood that terms such as "comprises" or "comprising," etc., are intended to indicate the presence of features, numbers, steps, acts, components, portions, or combinations thereof disclosed in this specification, and are not intended to exclude the possibility that one or more other features, numbers, steps, acts, components, portions, or combinations thereof are present or added.
In addition, it should be noted that, without conflict, the embodiments of the present disclosure and features of the embodiments may be combined with each other. The present disclosure will be described in detail below with reference to the accompanying drawings in conjunction with embodiments.
In the present disclosure, if an operation of acquiring user information or user data or an operation of presenting user information or user data to another person is referred to, the operations are all operations authorized, confirmed, or actively selected by the user.
In the related art, when the valve is replaced, a self-wrapping sheet or a bovine pericardium patch can be cut and sewn to form a prosthetic valve material, so that the valve can be replaced by the prosthetic valve material in operation.
However, the applicant found that, due to the relatively simple shape of the above-mentioned prosthetic valve material, in the operation, it is often required to first cut the prosthetic valve material by a doctor and then replace the prosthetic valve with the cut prosthetic valve, and in this process, it is also required to ensure that the shape of the formed valve pocket after replacement is relatively similar to that of the valve pocket in the human body, so as to ensure that the opening and closing functions of the cut prosthetic valve after replacement are all perfect.
For example, the artificial valve sinus composite material formed by adopting a self pericardium sheet or cutting and sewing a bovine pericardium patch is generally square, in the operation, a doctor needs to cut the artificial valve sinus composite material of the square shape firstly to obtain an artificial valve sinus composite with a shape relatively close to that of the valve leaflet of the arterial valve, and the doctor manually sets the shape of the artificial valve sinus composite during replacement to form a valve pocket between the artificial valve sinus composite and the sinus wall, so that the shape of the valve pocket is relatively close to that of the valve pocket in a human body, and the opening and closing functions of the cut artificial valve sinus composite after replacement are all perfect.
Therefore, the scheme increases the operation difficulty of replacing the arterial valve and reduces the success rate of replacement.
In order to solve the above-mentioned problem, the technical solution provided by the embodiments of the present disclosure provides a prosthetic valve sinus complex, which includes a leaflet lower edge skirt and a leaflet, one surface of the leaflet lower edge skirt is used for being attached to and connected with an annulus, and the lower edge of the leaflet is connected with the other surface of the leaflet lower edge skirt, for forming a leaflet pocket between the leaflet and the sinus wall. In operation, a doctor only needs to cut the skirt edge of the lower edge of the valve leaflet according to the annular shape of the valve leaflet, then one surface of the skirt edge of the lower edge of the valve leaflet is attached to the annular and connected with the annular, a valve pocket can be formed between the valve leaflet and the sinus wall, the shape of the valve pocket is formed before replacement, the shape of the valve pocket is relatively similar to that of the valve pocket in a human body, and the opening and closing functions of the valve sinus complex of the artificial artery after replacement can be ensured to be perfect.
Fig. 1 illustrates a front view of a prosthetic valve sinus complex according to an embodiment of the present disclosure, fig. 2 illustrates a top view of the prosthetic valve sinus complex according to an embodiment of the present disclosure, and fig. 3 illustrates a longitudinal cross-sectional view of the prosthetic valve sinus complex according to an embodiment of the present disclosure. As shown in fig. 1-3, the prosthetic valve sinus complex includes a leaflet lower edge skirt 100 and a leaflet 200, one side of the leaflet lower edge skirt 100 being adapted to be attached to and connected with the annulus, and a lower edge 201 of the leaflet 200 being connected with the other side of the leaflet lower edge skirt 100 for forming a leaflet pocket 301 between the leaflet 200 and the sinus wall 300.
In one implementation of the present disclosure, the leaflet is integrally formed with the leaflet lower edge skirt, or the leaflet lower edge is sewn to the other side of the leaflet lower edge skirt.
In one implementation of the present disclosure, the leaflet, leaflet lower edge skirt, may be a homogenous tissue sheet, a chemically modified xenogeneic tissue sheet, or an artificial material patch. Wherein the heterologous tissue slices subjected to chemical modification treatment comprise animal pericardium subjected to anti-calcification modification treatment and arterial valves.
In the technical scheme provided by the embodiment of the disclosure, the artificial arterial valve sinus complex comprises a leaflet lower edge skirt and a leaflet, wherein one surface of the leaflet lower edge skirt is used for being attached to an annulus and connected with the annulus, and the lower edge of the leaflet is connected with the other surface of the leaflet lower edge skirt and used for forming a leaflet pocket between the leaflet and the sinus wall. In operation, a doctor only needs to cut the skirt edge of the lower edge of the valve leaflet according to the annular shape of the valve leaflet, then one surface of the skirt edge of the lower edge of the valve leaflet is attached to the annular and connected with the annular, a valve pocket can be formed between the valve leaflet and the sinus wall, the shape of the valve pocket is formed before replacement, the shape of the valve pocket is relatively similar to that of the valve pocket in a human body, and the opening and closing functions of the valve sinus complex of the artificial artery after replacement can be ensured to be perfect.
In one embodiment of the present disclosure, fig. 4 shows an elevation view of a prosthetic valve sinus complex according to an embodiment of the present disclosure. As shown in fig. 4, between the upper edge 202 of the leaflet 200 and the lower edge 201 of the leaflet 200, an upper edge arm 400 protrudes from the outside of the leaflet 200, and an end of the upper edge arm 400 is used to connect with the sinus wall 300.
In the technical scheme, after the prosthetic valve sinus complex is used for replacing an arterial valve, the extension degree of the upper edge arm is increased along with the increase of the diameter of the arterial valve, so that the size of an opening of a valve pocket is increased along with the increase of the diameter of the arterial valve sinus complex, and the situation that the prosthetic valve sinus complex is not closed incompletely is ensured.
In one embodiment of the present disclosure, as shown in fig. 4, the prosthetic valve sinus complex further includes an upper rim arm skirt 500, one face of the upper rim arm skirt 500 being connected to the end of the upper rim arm 400, and the other face of the upper rim arm skirt 500 being adapted to be connected to the sinus wall 300.
In one embodiment of the present disclosure, the leaflet lower edge skirt, and the upper edge arm skirt are integrally formed;
Or the lower edge of the valve leaflet is sewed with the other surface of the lower edge skirt of the valve leaflet, and one surface of the upper edge arm skirt is sewed with the end part of the upper edge arm.
In one embodiment of the present disclosure, the leaflet, leaflet lower edge skirt and upper edge arm skirt are pieces of the same tissue, chemically modified pieces of a heterologous tissue, or patches of an artificial material.
In one embodiment of the present disclosure, the chemically modified xenogeneic tissue sheets include anti-calcified modified animal pericardium and arterial valves.
In the technical scheme, when the prosthetic valve sinus complex is used for replacing an arterial valve, a doctor can directly attach and connect the other surface of the skirt edge of the upper edge arm with the sinus wall, so that the operation difficulty in replacing the arterial valve is reduced, and the success rate of replacement is improved.
In one embodiment of the present disclosure, the upper edge of the leaflet is a convex structure that gradually decreases from the middle to both ends.
In the technical scheme, the upper edge of the valve leaflet is of a convex structure gradually decreasing from the middle part to the two ends, so that the artificial valve sinus complex is more similar to the shape of an aortic valve in a human body, and the closing condition of the artificial valve sinus complex and other autologous arterial valves is better.
In one embodiment of the present disclosure, fig. 5 shows a top view of a prosthetic valve sinus complex according to an embodiment of the present disclosure, and fig. 6 shows a longitudinal cross-sectional view of a prosthetic valve sinus complex according to an embodiment of the present disclosure. As shown in fig. 5-6, the prosthetic valve sinus complex further includes a prosthetic sinus wall 600 removably attached to the leaflet skirt 100, the prosthetic sinus wall 600 being adapted to be attached to the sinus wall.
In one implementation of the present disclosure, a plurality of break points may be provided along the line of attachment of the artificial sinus wall to the leaflet lower edge skirt, such that a frangible line structure is formed along the line of attachment, such that the two may be torn along the frangible line structure during surgery to separate the two, or the artificial sinus wall may be bonded to the leaflet lower edge skirt, such that the two may be separated during surgery.
The leaflet lower edge skirt 100 and the artificial sinus wall 600 may be integrally formed, and the artificial sinus wall 600 may be cut off along the annulus after suturing. The artificial sinus wall 600 is removed for replacement of the left and right coronary valves, and the artificial sinus wall may not be removed for replacement of the non-coronary and pulmonary valves, and the artificial sinus wall may be used to reinforce the autologous sinus wall.
In the above technical solution, the prosthetic valve sinus complex further includes a prosthetic sinus wall detachably connected to the leaflet skirt, the prosthetic sinus wall being adapted to be attached to the sinus wall. Before operation, the shape of the skirt edge of the lower edge of the valve leaflet can be fixed by the artificial sinus wall, so that the shape of the artificial valve sinus complex is not easy to deform, the shape of the artificial valve sinus complex is further ensured to be relatively close to the shape of a valve pocket in a human body, the opening and closing functions of the artificial valve sinus complex after replacement are all perfect, and in operation, when a doctor attaches the artificial sinus wall to the sinus wall and attaches and connects one surface of the skirt edge of the lower edge of the valve leaflet to the sinus wall, the artificial sinus wall can be separated from the skirt edge of the lower edge of the valve leaflet, so that the normal functions of the artificial valve sinus complex are not affected.
The foregoing description is only of the preferred embodiments of the present disclosure and description of the principles of the technology being employed. It will be appreciated by those skilled in the art that the scope of the invention referred to in this disclosure is not limited to the specific combination of features described above, but encompasses other embodiments in which any combination of features described above or their equivalents is contemplated without departing from the inventive concepts described. Such as those described above, are mutually substituted with the technical features having similar functions disclosed in the present disclosure (but not limited thereto).

Claims (8)

Translated fromChinese
1.一种人工动脉瓣膜瓣窦复合体,其特征在于,所述人工动脉瓣膜瓣窦复合体包括瓣叶下缘裙边和瓣叶;1. An artificial arterial valve sinus complex, characterized in that the artificial arterial valve sinus complex comprises a valve leaflet lower edge skirt and a valve leaflet;所述瓣叶下缘裙边的一面用于与瓣环相贴并与所述瓣环连接;One side of the lower edge of the leaflet skirt is used to adhere to the valve ring and be connected to the valve ring;所述瓣叶的下缘与所述瓣叶下缘裙边的另一面连接,用于在所述瓣叶与窦壁之间形成瓣兜;The lower edge of the leaflet is connected to the other side of the skirt of the lower edge of the leaflet, so as to form a leaflet pocket between the leaflet and the sinus wall;在所述瓣叶的上缘与所述瓣叶的下缘之间从所述瓣叶外凸出上缘臂,所述上缘臂的端部用于与所述窦壁连接,所述上缘臂的延展程度随着动脉直径的增长而增加;An upper edge arm protrudes from the outside of the leaflet between the upper edge of the leaflet and the lower edge of the leaflet, the end of the upper edge arm is used to connect with the sinus wall, and the extension of the upper edge arm increases with the increase of the diameter of the artery;其中,人工动脉瓣膜瓣窦复合体还包括上缘臂裙边,所述上缘臂裙边的一面与所述上缘臂的端部连接,所述上缘臂裙边的另一面用于与所述窦壁连接。The artificial arterial valve sinus complex further includes an upper arm skirt, one side of the upper arm skirt is connected to the end of the upper arm, and the other side of the upper arm skirt is used to connect to the sinus wall.2.根据权利要求1所述的人工动脉瓣膜瓣窦复合体,其特征在于,所述瓣叶与所述瓣叶下缘裙边一体成型;2. The artificial aortic valve sinus complex according to claim 1, wherein the valve leaflet and the lower edge skirt of the valve leaflet are integrally formed;或,所述瓣叶的下缘与所述瓣叶下缘裙边的另一面缝合。Alternatively, the lower edge of the leaflet is sutured to the other side of the skirt of the lower edge of the leaflet.3.根据权利要求1所述的人工动脉瓣膜瓣窦复合体,其特征在于,所述瓣叶、所述瓣叶下缘裙边与所述上缘臂裙边一体成型;3. The artificial arterial valve sinus complex according to claim 1, wherein the valve leaflet, the valve leaflet lower edge skirt and the upper edge arm skirt are integrally formed;或,所述瓣叶的下缘与所述瓣叶下缘裙边的另一面缝合,所述上缘臂裙边的一面与所述上缘臂的端部缝合。Alternatively, the lower edge of the leaflet is sutured to the other side of the lower edge skirt of the leaflet, and one side of the upper edge arm skirt is sutured to the end of the upper edge arm.4.根据权利要求1所述的人工动脉瓣膜瓣窦复合体,其特征在于,所述瓣叶、所述瓣叶下缘裙边与所述上缘臂裙边为同种组织片、经化学改性处理的异种组织片或人工材料补片。4. The artificial arterial valve sinus complex according to claim 1 is characterized in that the leaflets, the lower edge skirt of the leaflets and the upper edge arm skirt are homologous tissue sheets, chemically modified heterologous tissue sheets or artificial material patches.5.根据权利要求4所述的人工动脉瓣膜瓣窦复合体,其特征在于,所述经化学改性处理的异种组织片包括经抗钙化改性处理的动物心包膜以及动脉瓣膜。5 . The artificial arterial valve sinus complex according to claim 4 , wherein the chemically modified heterogeneous tissue sheet comprises an animal pericardium and an arterial valve that have been treated with anti-calcification modification.6.根据权利要求1所述的人工动脉瓣膜瓣窦复合体,其特征在于,所述瓣叶的上缘为从中部向两端逐渐降低的凸起结构。6 . The artificial aortic valve sinus complex according to claim 1 , wherein the upper edge of the valve leaflet is a convex structure that gradually descends from the middle to both ends.7.根据权利要求1所述的人工动脉瓣膜瓣窦复合体,其特征在于,所述人工动脉瓣膜瓣窦复合体还包括与所述瓣叶下缘裙边连接的人工窦壁,所述人工窦壁用于与窦壁相贴。7. The artificial arterial valve sinus complex according to claim 1 is characterized in that the artificial arterial valve sinus complex also includes an artificial sinus wall connected to the lower edge skirt of the valve leaflet, and the artificial sinus wall is used to adhere to the sinus wall.8.根据权利要求7所述的人工动脉瓣膜瓣窦复合体,其特征在于,所述瓣叶下缘裙边通过可拆卸结构与所述人工窦壁的连接。8. The artificial arterial valve sinus complex according to claim 7, characterized in that the lower edge skirt of the valve leaflet is connected to the artificial sinus wall via a detachable structure.
CN202411496376.6A2024-10-242024-10-24 Artificial aortic valve sinus complexActiveCN119033509B (en)

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