Disclosure of Invention
In order to overcome at least one of the problems in the related art, the present invention provides a medical ultrasound ablation device control system.
Wherein, ultrasonic ablation equipment control system includes:
an ultrasonic power generator;
an impedance matching unit;
an ultrasonic transducer which receives the electric power of the ultrasonic power generator and outputs acoustic power;
and the control unit acquires the first characteristic parameter of the ultrasonic power generator and the second characteristic parameter of the ultrasonic transducer, and adjusts the third characteristic parameter of the impedance matching unit according to the first characteristic parameter and the second characteristic parameter.
In some alternative embodiments, the first characteristic parameter includes at least an impedance of the ultrasonic power generator, and the second characteristic parameter includes at least an impedance of the ultrasonic transducer;
the control unit obtains a third characteristic parameter applicable to the impedance matching unit according to the impedance of the ultrasonic power generator and the impedance of the ultrasonic transducer.
In some optional embodiments, the impedance matching unit includes a plurality of switches, and the control unit adjusts the corresponding switches to be closed according to the third characteristic parameter.
In some optional embodiments, the control system further includes a current sampling unit for collecting an output current of the ultrasonic power generator;
and the control unit controls the output current of the ultrasonic power generator according to the third characteristic parameter so as to adjust the output power of the ultrasonic transducer to a target value.
In some alternative embodiments, the controlling the output current of the ultrasonic power generator to adjust the output power of the ultrasonic transducer to a target value includes:
acquiring an output power target value of an ultrasonic transducer;
and comparing the target value of the output power of the ultrasonic transducer with the actual value of the output power of the ultrasonic transducer, and if the difference value between the target value and the actual value does not reach the set target, adjusting the output current of the ultrasonic power generator.
In some alternative embodiments, comparing the target value of the output power of the ultrasonic transducer with the actual value of the output power of the ultrasonic transducer, and if the difference between the target value and the actual value does not reach the set target, adjusting the output current of the ultrasonic power generator, including:
and adjusting the output current of the ultrasonic power generator in a closed-loop control mode so as to enable the output power of the ultrasonic transducer to reach a target value.
In some alternative embodiments, the adjusting the output current of the ultrasonic power generator in a closed-loop control manner includes:
the control unit obtains the gain parameter of the ultrasonic power generator, and based on the gain parameter, the third characteristic parameter, the impedance of the ultrasonic power generator and the target value, adopts a closed-loop control mode to control the amplitude of the output signal so as to change the output current of the ultrasonic power generator.
In some alternative embodiments, the current sampling unit includes at least one of a hall current measurement unit or a sampling resistor.
In alternative embodiments, the control unit adjusts the output current of the ultrasonic power generator via a DDS or DAC.
The technical scheme of the invention has the following advantages or beneficial effects:
(1) According to the invention, the impedance of the ultrasonic power generator and the impedance of the ultrasonic transducer are matched through the impedance matching unit, so that the ultrasonic transducer with poor parameter consistency can be connected to the same ultrasonic power generator, and a good impedance matching effect is obtained. Thereby improving the efficiency of the ultrasonic power generator, the effective power of the ultrasonic transducer and the like, improving the energy utilization efficiency, effectively improving the ultrasonic ablation effect, solving the problems of serious heating of cables, damage of the power generator and the like.
(2) According to the invention, the output current of the ultrasonic power generator is regulated, so that the output power of the ultrasonic transducer is accurately controlled, the ultrasonic transducer stably works at the target power, the working stability and reliability of an ultrasonic ablation equipment control system are improved, and the use experience of users is improved.
(3) The invention realizes the accurate control of the output power of the ultrasonic transducer by controlling the output current of the ultrasonic power generator in a closed loop. Avoiding various difficulties faced by directly measuring and controlling the output power of the ultrasonic transducer; the purpose of controlling the output power of the ultrasonic transducer with low cost, high reliability and high precision is achieved.
Detailed Description
Exemplary embodiments of the present invention will now be described with reference to the accompanying drawings, in which various details of the embodiments of the present invention are included to facilitate understanding, and are to be considered merely exemplary. Accordingly, those of ordinary skill in the art will recognize that various changes and modifications of the embodiments described herein can be made without departing from the scope and spirit of the invention. Also, descriptions of well-known functions and constructions are omitted in the following description for clarity and conciseness.
The terminology used in the present application is for the purpose of describing particular embodiments only and is not intended to be limiting of the present application. As used in this application and the appended claims, the singular forms "a," "an," and "the" are intended to include the plural forms as well, unless the context clearly indicates otherwise. It should also be understood that the term "and/or" as used herein refers to and encompasses any or all possible combinations of one or more of the associated listed items.
It should be understood that although the terms first, second, third, etc. may be used herein to describe various information, these information should not be limited by these terms. These terms are only used to distinguish one type of information from another. For example, a first message may also be referred to as a second message, and similarly, a second message may also be referred to as a first message, without departing from the scope of the present application. The word "if" as used herein may be interpreted as "at … …" or "at … …" or "responsive to a determination", depending on the context.
Currently, it is common to treat hypertension using ultrasound ablation techniques. However, the ultrasonic transducer for renal artery ablation has extremely small size and needs high electroacoustic conversion efficiency, so that the processing technology is complex, the consistency of transducer parameters is poor, and parameters between the transducer and an ultrasonic power generator are difficult to match. For example, the impedance between the ultrasonic power generator and the ultrasonic transducer is difficult to match. In particular, when the ultrasonic transducer has poor parameter consistency, a large variation range exists between the resonant frequency and the impedance, so that the impedance between the ultrasonic power generator and the ultrasonic transducer cannot be matched accurately. When the impedance between the power generator and the transducer is not matched, the efficiency of the power generator, the effective power of the transducer end and the like are greatly reduced, the ultrasonic ablation effect is poor, and the cable is seriously heated and damaged. In other use cases, the ultrasonic transducer is placed in the balloon catheter, the ultrasonic power generator and the ultrasonic transducer are connected through a connecting wire with the length of 2 to 3 meters, and multiple switching positions exist on the connecting wire. The connection line is usually a coaxial cable. The wiring mode leads to a large variation range of the resonant frequency and impedance of different transducers with poor parameter consistency, and when the transducers are connected into the same ultrasonic power generator, the output electric power of the ultrasonic transducers is difficult to control accurately.
In order to overcome at least one of the problems in the related art, the present invention provides a medical ultrasound ablation device control system. Wherein, ultrasonic ablation equipment control system includes: an ultrasonic power generator; an impedance matching unit; an ultrasonic transducer which receives the electric power of the ultrasonic power generator and outputs acoustic power; and the control unit acquires the first characteristic parameter of the ultrasonic power generator and the second characteristic parameter of the ultrasonic transducer, and adjusts the third characteristic parameter of the impedance matching unit according to the first characteristic parameter and the second characteristic parameter.
Fig. 1 shows a schematic structural diagram of a control system of an ultrasonic ablation device. The ultrasonic ablation equipment control system main body comprises: an ultrasonic power generator 101 (or as shown in fig. 2, the ultrasonic power generator is indicated by G1), an impedance matching unit 110, an ultrasonic transducer 107, and the like. The impedance matching unit 110 is disposed between the ultrasonic power generator 101 and the ultrasonic transducer 107, and the three are electrically connected in sequence. So that the output power of the ultrasonic power generator 101 is transferred to the ultrasonic transducer 107 through the impedance matching unit 110. The ultrasonic transducer 107 is arranged in the balloon catheter 109, so that the ultrasonic transducer 107 reaches a target point in the process of being inserted into a human body along with the balloon catheter 109. And then the electric power transmitted by the ultrasonic power generator 101 is converted into sound power and acts on the target tissue to achieve the purpose of ablation. In practice, due to the small size of balloon catheters, the size of the ultrasound transducers placed therein is small, and it is difficult to detect and control the output power and impedance matching of the ultrasound transducers by conventional means. Further, the control system further includes a control unit 102, where the control unit 102 is capable of acquiring the first characteristic parameter of the ultrasonic power generator and the second characteristic parameter of the ultrasonic transducer, and adjusting the third characteristic parameter of the impedance matching unit according to the first characteristic parameter and the second characteristic parameter. That is, according to the first characteristic parameter and the second characteristic parameter, a third characteristic parameter matching the two characteristic parameters can be obtained. In some embodiments, the first characteristic parameter comprises at least an impedance of the ultrasonic power generator and the second characteristic parameter comprises at least an impedance of the ultrasonic transducer. In some embodiments, the second characteristic parameter may include an impedance parameter and/or a frequency parameter. The control unit obtains a third characteristic parameter applicable to the impedance matching unit according to the impedance of the ultrasonic power generator and the impedance of the ultrasonic transducer. It should be noted that, the impedance matching unit 110 is used to match the impedance of the ultrasonic power generator with the impedance of the ultrasonic transducer, so as to improve the efficiency of the ultrasonic power generator, the effective power of the ultrasonic transducer, and the like, improve the energy utilization efficiency, effectively improve the ultrasonic ablation effect, and solve the problems of serious cable heating, damage to the power generator, and the like. In some embodiments, the ultrasound transducer 107 may have integrated therein a data storage unit 106, such as the components shown as IC1 in FIG. 1. The data storage unit 106 has recorded therein transducer impedance data, frequency data, and the like, which have been calibrated. As described above, the processing technology of the ultrasonic transducer is complex and difficult, resulting in poor consistency of impedance data, frequency data, and the like. Correspondingly, a data storage unit is also arranged in the ultrasonic power generator, and information such as impedance data of the ultrasonic generator is recorded in the data storage unit. In other embodiments, the impedance data of the ultrasonic power generator is a default value that is directly used as input information to the data processing unit, without being pre-stored in the ultrasonic power generator. The control unit 102 is electrically connected with the ultrasonic power generator and the ultrasonic transducer respectively, so as to communicate with the ultrasonic power generator and the ultrasonic transducer, and further independently perform impedance matching on various ultrasonic transducers with poor parameter consistency respectively; so that the same ultrasonic power generator can be adapted to a plurality of ultrasonic transducers with poor parameter consistency. The same ultrasonic power generator comprises the same ultrasonic power generator or the same type of ultrasonic power generator.
In some alternative embodiments, the impedance matching unit includes a plurality of switches 104, and the control unit adjusts the corresponding switches to be closed according to the third characteristic parameter. In the embodiment shown in fig. 1, the impedance matching unit 110 is shown having a transformer 105 disposed therein, and a switching unit is disposed on at least one of a primary side or a secondary side of the transformer. The switching unit may include a plurality of switches S1, switches 2, … …, and switches Sx, for example. It can be understood that the more the number of switches, the more the transformation ratio between the primary side and the secondary side of the transformer is, the more accurate matching of the impedance can be achieved. When the primary side and the secondary side are provided with a plurality of switches, the control device can also realize various transformation ratio working conditions. The primary side is electrically connected with the ultrasonic power generator; the secondary side is connected to an ultrasonic transducer 107 by a cable 108. The cable 108 may be a coaxial cable. As shown in fig. 1, according to the impedance Z of the transducer1 Different switches S1, S2 and Sx are selected to be closed, so that different primary side/secondary side transformation ratios N of the transformer can be obtained1 ，N2 ......，Nx . In practice, the impedance of the output of the ultrasonic power generator is a fixed value, which can be obtained by the control unit reading the data storage unit of the ultrasonic power generator, where the impedance of the ultrasonic power generator is denoted as Z2 . In use, the actual impedance Z of the ultrasound transducer according to the access control system1 And impedance Z of the ultrasonic power generator2 Calculating a third characteristic parameter of the corresponding impedance matching unit, namely the primary side/secondary side transformation ratio N of the transformerx Then according to the primary side/secondary side transformation ratio N of the transformerx Impedance matching between the ultrasonic transducer and the ultrasonic power generator can be realized by controlling the corresponding switch. Specifically, the calculation formula is as follows:
wherein Z is1 Refers to the impedance of the ultrasonic transducer; n (N)x Refers to the primary/secondary transformer ratio of the transformer; z is Z2 Refers to the impedance of the ultrasonic power generator.
In some optional embodiments, the control system further includes a current sampling unit 111 for collecting an output current of the ultrasonic power generator; and the control unit controls the output current of the ultrasonic power generator according to the third characteristic parameter so as to adjust the output power of the ultrasonic transducer to a target value. In practical use, the output power of the ultrasonic transducer is an important control target, and the control accuracy of specific numerical values of the output power directly influences the ablation effect. It can be appreciated that when the ablation power is low, it is difficult to effectively achieve the ablation purpose, and the user needs to repeatedly operate the ablation device to achieve the desired ablation purpose, which results in problems of prolonged operation time, poor operation experience, and the like. When the ablation power exceeds a predetermined value, excessive power will cause ablation of non-target sites with irreversible consequences. For this reason, it is important how to precisely control the precise output of the ultrasonic transducer power. In some embodiments of the present invention, the ultrasonic power generator is connected to the ultrasonic transducer through an impedance matching module. Therefore, the primary side current of the transformer of the impedance matching module reflects the output current value of the ultrasonic power generator, the secondary side current reflects the input current of the ultrasonic transducer, and the output current I of the ultrasonic power generator can be reflected by collecting the primary side current2 . Further, the current and the actual output power of the ultrasonic transducer can be calculated by the following formula.
I1 ＝Nx ×I2
Wherein Z is1 Refers to the impedance of the ultrasonic transducer; n (N)x Refers to the primary/secondary transformer ratio of the transformer; i1 Refers to the output current of an ultrasonic transducer, P0 Refers to the actual output power value of the ultrasonic transducer, I2 Refers to the output current of the ultrasonic power generator.
In some embodiments, the output power of the ultrasound transducer may be detected and adjusted in real time to obtain a set output power target value. However, since the ultrasonic transducer is small in size and is located inside the human body in an operating state, the difficulty of detecting real-time power is great. To this end, the present invention provides another method of precisely adjusting the output power of an ultrasonic transducer, as described in detail below.
In some alternative embodiments, the controlling the output current of the ultrasonic power generator to adjust the output power of the ultrasonic transducer to a target value includes: acquiring an output power target value of an ultrasonic transducer; and comparing the target value of the output power of the ultrasonic transducer with the actual value of the output power of the ultrasonic transducer, and if the difference value between the target value of the output power of the ultrasonic transducer and the actual value of the output power of the ultrasonic transducer does not reach the set threshold value, adjusting the output current of the ultrasonic power generator. In some alternative embodiments, comparing the target value of the output power of the ultrasonic transducer with the actual value of the output power of the ultrasonic transducer, and if the difference between the target value and the actual value does not reach the set threshold value, adjusting the output current of the ultrasonic power generator, including: and adjusting the output current of the ultrasonic power generator in a closed-loop control mode so as to enable the output power of the ultrasonic transducer to reach a target value. The specific equation is as follows:
I1 ＝Nx ×I2
I2 ＝g×V1
Pset ＝(Nx ×g×V1 )2 ×Z1
wherein Z is1 Refers to the impedance of the ultrasonic transducer; n (N)x Refers to the primary/secondary transformer ratio of the transformer; i1 Finger ultrasound transductionOutput current of the device, Pset Refers to the output power target value of the ultrasonic transducer, I2 Referring to the output current of the ultrasonic power generator, g refers to the output signal amplitude V of the control unit 1021 With the output current I of the ultrasonic power generator2 Gain parameters in between.
Due to the amplitude V of the output signal of the control unit1 With the output current I of the ultrasonic power generator2 There is a correlation between, in particular embodied by the gain parameter g described above, so that the signal amplitude V can be calculated by the above formula1 By the amplitude V of the combined signals1 The output current of the ultrasonic power generator is adjusted to adjust the output power of the ultrasonic transducer to a target value. In practice, as shown in the control structure diagram of fig. 2, the target value of the output power of the ultrasonic transducer and the actual value of the output power of the ultrasonic transducer may be compared, and whether the adjustment needs to be continued or terminated may be determined by comparing the difference between the target value and the actual value of the output power of the ultrasonic transducer with the set target. Specifically, a threshold value or a threshold value range can be preset, and if the difference value between the two values does not reach the set threshold value or the threshold value range, the adjustment process is continuously executed; when the difference reaches a set threshold or lies within a threshold range, the adjustment is terminated.
In some alternative embodiments, the adjusting the output current of the ultrasonic power generator in a closed-loop control manner includes: the control unit obtains the gain parameter of the ultrasonic power generator, and based on the gain parameter, the third characteristic parameter, the impedance of the ultrasonic power generator and the target value, adopts a closed-loop control mode to control the amplitude of the output signal so as to change the output current of the ultrasonic power generator. As described above, in order to precisely control the acoustic power of the output of the ultrasonic transducer, it is possible to detect and control the output current of the ultrasonic power generator, thereby effectively solving the problems that the ultrasonic transducer is integrated in the balloon catheter and it is difficult to monitor the real-time power thereof in a state of being interposed in the human body. It will be appreciated that the ablation device 103 is positioned outside the body with sufficient room to mount control, adjustment means to precisely control the output parameters of the ultrasound power generator. Specifically, on the basis of the set output power target value of the ultrasonic transducer, the output current amplitude of the corresponding ultrasonic power generator can be calculated. The output current of the ultrasonic power generator is controlled in a closed loop mode, so that the output power of the ultrasonic transducer approaches to a target value, and finally, the accurate control of the output power of the ultrasonic transducer is realized. The closed-loop control algorithm comprises PI, PID or PD modes and the like.
In some alternative embodiments, the current sampling unit includes at least one of a hall current measurement unit or a sampling resistor. In the embodiment shown in fig. 1, a current sampling unit 111 is disposed on an output line of the ultrasonic power generator to accurately obtain a current value of a primary circuit, so as to accurately control the output power of the ultrasonic transducer. Specifically, a high-precision current measurement unit may be used to obtain a real-time current output value of the ultrasonic power generator, for example, a hall current measurement unit or a sampling resistor may be used to measure the current value.
In alternative embodiments, the control unit adjusts the output current amplitude of the ultrasonic power generator via a DDS or DAC. In the example shown in fig. 1, the control unit 102 is configured to adjust parameters such as the amplitude of the output current of the ultrasonic power generator. In practice, the control unit may incorporate a corresponding converter to effect the adjustment of the output amplitude. For example, the output current amplitude of the ultrasonic power generator may be adjusted by a direct digital frequency synthesizer DDS or a digital-to-analog converter DAC, etc.
The above embodiments do not limit the scope of the present invention. Other embodiments of the disclosure will be apparent to those skilled in the art from consideration of the specification and practice of the disclosed subject matter. This application is intended to cover any adaptations, uses, or adaptations of the disclosure following, in general, the principles of the disclosure and including such departures from the present disclosure as come within known or customary practice within the art to which the disclosure pertains. It is intended that the specification and examples be considered as exemplary only, with a true scope and spirit of the disclosure being indicated by the following claims.
It is to be understood that the present disclosure is not limited to the precise arrangements and instrumentalities shown in the drawings, and that various modifications and changes may be effected without departing from the scope thereof. The scope of the present disclosure is limited only by the appended claims.