技术领域technical field
本发明涉及口含制品技术领域，尤其涉及一种含有辣椒素提取物的口含制品及其制备方法。The invention relates to the technical field of oral products, in particular to an oral product containing capsaicin extract and a preparation method thereof.
背景技术Background technique
市面上常见的尼古丁制品主要通过口含、含化、咀嚼等方式向消费者提供一定的尼古丁满足感，而尼古丁易挥发，因此口含制品通常是将尼古丁以尼古丁盐的形式添加至其中或者将尼古丁与尼古丁盐进行复配。而此种口含制品存在刺激性弱、辣感低的缺陷，现有技术通常是通过调节口含制品的碱性来增加刺激性，以求高效地达到生理满足。但是在调节过程中往往存在因碱性过高而导致尼古丁氧化的问题，从而影响到口含制品的口感及外观。因此，需要寻求一种刺激性较强、尼古丁满足感较高且不易氧化的口含制品。The common nicotine products on the market mainly provide consumers with a certain sense of nicotine satisfaction through oral, chewing, etc., and nicotine is volatile, so oral products usually add nicotine to them in the form of nicotine salt or Nicotine is compounded with nicotine salt. However, this oral product has the disadvantages of weak irritation and low spicy feeling. In the prior art, the irritation is usually increased by adjusting the alkalinity of the oral product in order to achieve physiological satisfaction efficiently. However, in the adjustment process, there is often the problem of nicotine oxidation due to excessive alkalinity, thereby affecting the mouthfeel and appearance of the oral product. Therefore, it is necessary to seek a buccal product with strong stimulation, high nicotine satisfaction and non-oxidative resistance.
辣椒素作为一种常见的天然食品添加剂，具有增加食欲、开胃消食的作用。此外，药理实验表明辣椒素具有抗癌、抗疲劳、镇痛等作用。将辣椒素加入到口含制品中，可以增加口含制品的辣感，快速达到提神醒脑的效果，满足消费者对口含制品刺激性的需求。As a common natural food additive, capsaicin has the effects of increasing appetite, appetizing and eliminating food. In addition, pharmacological experiments have shown that capsaicin has anti-cancer, anti-fatigue, and analgesic effects. Adding capsaicin to the oral products can increase the spicy feeling of the oral products, quickly achieve the refreshing effect, and satisfy consumers' demand for the stimulation of the oral products.
发明内容Contents of the invention
为解决上述技术问题，本发明提供一种含有辣椒素提取物的口含制品及其制备方法。具体包括以下技术方案：In order to solve the above technical problems, the present invention provides a buccal product containing capsaicin extract and a preparation method thereof. Specifically, the following technical solutions are included:
第一方面，提供一种含有辣椒素提取物的口含制品，包括以下重量份组分：辣椒素提取物5-20份，尼古丁盐1-15份，保湿剂1-15份，甜味剂1-10份，凉味剂0.1-1份，抗氧化剂0.01-5份，香精1-20份，微晶纤维素30-60份，麦芽糖醇1-20份，阿拉伯树胶溶液20-40份，山梨酸钾0.01-0.1份，碳酸钙0.1-1份，碳酸氢钠1-5份。In the first aspect, there is provided an oral product containing capsaicin extract, comprising the following components in parts by weight: 5-20 parts of capsaicin extract, 1-15 parts of nicotine salt, 1-15 parts of humectant, and sweetener 1-10 parts, cooling agent 0.1-1 part, antioxidant 0.01-5 parts, essence 1-20 parts, microcrystalline cellulose 30-60 parts, maltitol 1-20 parts, gum arabic solution 20-40 parts, Potassium sorbate 0.01-0.1 part, calcium carbonate 0.1-1 part, sodium bicarbonate 1-5 part.
进一步的，所述的辣椒素提取物的制备方法，包括以下步骤：Further, the preparation method of described capsaicin extract comprises the following steps:
(1)新鲜辣椒去籽、去梗，置于55-60℃的恒温干燥箱中烘干，粉碎后过60-70目筛，得辣椒粉末；(1) Remove seeds and stems from fresh peppers, place them in a constant temperature drying oven at 55-60° C. for drying, and pass through a 60-70 mesh sieve after crushing to obtain pepper powder;
(2)将步骤(1)所得的辣椒粉末置于锥形瓶中，加入质量分数为70％的乙醇溶液浸泡0.5-1h后，用微波250W提取1.0-1.5h，旋转蒸发得辣椒素粗提物；(2) Place the capsicum powder obtained in step (1) in an Erlenmeyer flask, add a mass fraction of 70% ethanol solution to soak for 0.5-1h, extract with microwave 250W for 1.0-1.5h, and rotary evaporate to obtain capsaicin crude extraction thing;
(3)取D101大孔树脂，用质量分数为95％的乙醇浸泡24-26h后，采用湿法装柱；用乙醇冲洗树脂，直到流出液变得澄清无杂质；再用纯化水冲洗树脂，直到冲洗液无乙醇气味；用3～5BV(BV：树脂床体积)的质量分数为10％的盐酸冲洗，浸泡3.0-4.0h；用纯化水冲洗，直到流出液的PH值为5～7；用3～5BV的质量分数为7％的氢氧化钠冲洗，浸泡3.0-4.0h，用纯化水冲洗，直到流出液的PH值变为5～7，得到处理完毕的树脂；(3) Take D101 macroporous resin, soak it in ethanol with a mass fraction of 95% for 24-26h, and then pack it in a wet method; rinse the resin with ethanol until the effluent becomes clear and free of impurities; then rinse the resin with purified water, Until the washing solution has no ethanol smell; rinse with 3-5BV (BV: resin bed volume) of hydrochloric acid with a mass fraction of 10%, soak for 3.0-4.0h; rinse with purified water until the pH value of the effluent is 5-7; Rinse with 3-5BV of sodium hydroxide with a mass fraction of 7%, soak for 3.0-4.0h, and rinse with purified water until the pH value of the effluent becomes 5-7 to obtain the treated resin;
(4)将步骤(2)所得的辣椒素粗提物过滤后，沿壁缓慢倒入步骤(3)所得的处理完毕的树脂，待吸附平衡后用8BV的质量分数为70％的乙醇以1mL/min的速度洗脱，收集洗脱液旋转蒸发浓缩，冷冻干燥，即得辣椒素提取物。(4) After filtering the capsaicin crude extract obtained in step (2), slowly pour the processed resin obtained in step (3) along the wall, and after the adsorption equilibrium, use 8BV of mass fraction to be 70% ethanol with 1mL /min speed elution, the collected eluate is concentrated by rotary evaporation, and freeze-dried to obtain the capsaicin extract.
进一步的，所述的尼古丁盐选自酒石酸-尼古丁盐、乳酸尼古丁盐、树脂尼古丁中的一种或多种。Further, the nicotine salt is selected from one or more of tartrate-nicotine salt, lactic acid nicotine salt, and resin nicotine.
进一步的，所述的保湿剂为丙二醇、丙三醇中的一种或多种。Further, the humectant is one or more of propylene glycol and glycerin.
进一步的，所述的甜味剂选自安赛蜜、三氯蔗糖、蔗糖中的一种或多种。Further, the sweetener is selected from one or more of acesulfame potassium, sucralose, and sucrose.
进一步的，所述的凉味剂选自WS-3(N-乙基-2-异丙基-5-甲基-环己烷甲酰胺)、WS-23(N,2,3-三甲基-2-异丙基丁酰胺)中的一种或多种。Further, the cooling agent is selected from WS-3 (N-ethyl-2-isopropyl-5-methyl-cyclohexanecarboxamide), WS-23 (N,2,3-trimethyl One or more of base-2-isopropylbutanamide).
进一步的，所述的抗氧化剂选自维生素C、维生素E中的一种或多种。Further, the antioxidant is selected from one or more of vitamin C and vitamin E.
进一步的，所述的香精选自荔枝香精、柠檬香精、薄荷香精中的一种或多种。Further, the flavor is selected from one or more of lychee flavor, lemon flavor and mint flavor.
进一步的，所述的含有辣椒素提取物的口含制品包括以下重量份组分：Further, the described oral product containing capsaicin extract comprises the following components in parts by weight:
辣椒素提取物15份，尼古丁盐10份，保湿剂10份，甜味剂5份，凉味剂0.5份，抗氧化剂1份，香精10份，微晶纤维素40份，麦芽糖醇15份，阿拉伯树胶溶液30份，山梨酸钾0.05份，碳酸钙1份，碳酸氢钠3份。15 parts of capsaicin extract, 10 parts of nicotine salt, 10 parts of humectant, 5 parts of sweetener, 0.5 part of cooling agent, 1 part of antioxidant, 10 parts of essence, 40 parts of microcrystalline cellulose, 15 parts of maltitol, 30 parts of gum arabic solution, 0.05 parts of potassium sorbate, 1 part of calcium carbonate, and 3 parts of sodium bicarbonate.
第二方面，提供一种如第一方面所述的含有辣椒素提取物的口含制品的制备方法，包括以下步骤：In the second aspect, there is provided a method for preparing oral products containing capsaicin extract as described in the first aspect, comprising the following steps:
S1.按照各重量份精确称取各组分，取微晶纤维素、麦芽糖醇、甜味剂、凉味剂、抗氧化剂、山梨酸钾、碳酸钙、碳酸氢钠置于烧杯中，混合搅拌均匀，得到混合物；S1. Accurately weigh each component according to each weight part, take microcrystalline cellulose, maltitol, sweetener, cooling agent, antioxidant, potassium sorbate, calcium carbonate, sodium bicarbonate and place in a beaker, mix and stir Homogeneously, a mixture is obtained;
S2.往步骤S1所得的混合物中加入阿拉伯树胶溶液和保湿剂，再次搅拌均匀，选用60-70目筛网进行过筛处理，收集过筛后的粉末；S2. Add gum arabic solution and humectant to the mixture obtained in step S1, stir again evenly, select 60-70 mesh screen for sieving, and collect the sieved powder;
S3.往步骤S2所得的粉末中加入尼古丁盐、辣椒素提取物、香精，搅拌直至混合均匀；S3. Add nicotine salt, capsaicin extract, and essence to the powder obtained in step S2, and stir until evenly mixed;
S4.将步骤S3所得的产物进行分装，每份为0.5g，用无纺布包装成细长条型，封口机封口，灭菌，即得含有辣椒素提取物的口含制品。S4. Subpackage the product obtained in step S3, each portion is 0.5g, pack it into a long and thin strip with a non-woven fabric, seal it with a sealing machine, and sterilize it to obtain the oral product containing capsaicin extract.
本发明通过从辣椒中提取、纯化得到辣椒素提取物，将辣椒素提取物作为辅料之一加入到口含制品中，从而得到一种含有辣椒素提取物的口含制品，能够有效弥补以往尼古丁或尼古丁盐口含制品存在刺激性弱、辣感低的缺陷，避免通过调节口含制品碱性过高从而导致尼古丁氧化的问题。The present invention obtains capsaicin extract by extracting and purifying capsaicin, and adds the capsaicin extract into oral products as one of auxiliary materials, so as to obtain a oral product containing capsaicin extract, which can effectively compensate for nicotine in the past. Or the nicotine salt buccal product has the defects of weak irritation and low spicy feeling, so as to avoid the problem of nicotine oxidation caused by adjusting the buccal product to be too alkaline.
具体实施方式Detailed ways
下面将对本发明实施例中的技术方案进行清楚、完整地描述，显然，所描述的实施例是本发明一部分实施例，而不是全部的实施例。基于本发明中的实施例，本领域普通技术人员在没有做出创造性劳动前提下所获得的所有其他实施例，都属于本发明保护的范围。The technical solutions in the embodiments of the present invention will be clearly and completely described below, obviously, the described embodiments are part of the embodiments of the present invention, but not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by persons of ordinary skill in the art without making creative efforts belong to the protection scope of the present invention.
应当理解，当在本说明书和所附权利要求书中使用时，术语“包括”和“包含”指示所描述特征、整体、步骤、操作、元素和/或组件的存在，但并不排除一个或多个其它特征、整体、步骤、操作、元素、组件和/或其集合的存在或添加。It should be understood that when used in this specification and the appended claims, the terms "comprising" and "comprises" indicate the presence of described features, integers, steps, operations, elements and/or components, but do not exclude one or Presence or addition of multiple other features, integers, steps, operations, elements, components and/or collections thereof.
还应当理解，在此本发明说明书中所使用的术语仅仅是出于描述特定实施例的目的而并不意在限制本发明。如在本发明说明书和所附权利要求书中所使用的那样，除非上下文清楚地指明其它情况，否则单数形式的“一”、“一个”及“该”意在包括复数形式。It should also be understood that the terminology used in the description of the present invention is for the purpose of describing particular embodiments only and is not intended to be limiting of the present invention. As used in this specification and the appended claims, the singular forms "a", "an" and "the" are intended to include plural referents unless the context clearly dictates otherwise.
还应当进一步理解，在本发明说明书和所附权利要求书中使用的术语“和/或”是指相关联列出的项中的一个或多个的任何组合以及所有可能组合，并且包括这些组合。It should also be further understood that the term "and/or" used in the description of the present invention and the appended claims refers to any combination and all possible combinations of one or more of the associated listed items, and includes these combinations .
为了更充分理解本发明的技术内容，下面结合具体实施例对本发明的技术方案进一步介绍和说明。In order to fully understand the technical content of the present invention, the technical solution of the present invention will be further introduced and illustrated below in conjunction with specific embodiments.
本发明中所述的树脂尼古丁是指采用酸性树脂与液体尼古丁按同比或不同比例混合反应而成。The resin nicotine mentioned in the present invention is formed by mixing and reacting acidic resin and liquid nicotine in the same proportion or in different proportions.
含有辣椒素提取物的口含制品的制备方法：Preparation method of buccal product containing capsaicin extract:
S1.按照各重量份精确称取各组分，取微晶纤维素、麦芽糖醇、甜味剂、凉味剂、抗氧化剂、山梨酸钾、碳酸钙、碳酸氢钠置于烧杯中，混合搅拌均匀，得到混合物；S1. Accurately weigh each component according to each weight part, take microcrystalline cellulose, maltitol, sweetener, cooling agent, antioxidant, potassium sorbate, calcium carbonate, sodium bicarbonate and place in a beaker, mix and stir Homogeneously, a mixture is obtained;
S2.往步骤S1所得的混合物中加入阿拉伯树胶溶液和保湿剂，再次搅拌均匀，选用60-70目筛网进行过筛处理，收集过筛后的粉末；S2. Add gum arabic solution and humectant to the mixture obtained in step S1, stir again evenly, select 60-70 mesh screen for sieving, and collect the sieved powder;
S3.往步骤S2所得的粉末中加入尼古丁盐、辣椒素提取物、香精，搅拌直至混合均匀；S3. Add nicotine salt, capsaicin extract, and essence to the powder obtained in step S2, and stir until evenly mixed;
S4.将步骤S3所得的产物进行分装，每份为0.5g，用无纺布包装成细长条型，封口机封口，灭菌，即得含有辣椒素提取物的口含制品。S4. Subpackage the product obtained in step S3, each portion is 0.5g, pack it into a long and thin strip with a non-woven fabric, seal it with a sealing machine, and sterilize it to obtain the oral product containing capsaicin extract.
辣椒素提取物的制备方法Preparation method of capsaicin extract
(1)新鲜辣椒去籽、去梗，置于55-60℃的恒温干燥箱中烘干，粉碎后过60-70目筛，得辣椒粉末；(1) Remove seeds and stems from fresh peppers, place them in a constant temperature drying oven at 55-60° C. for drying, and pass through a 60-70 mesh sieve after crushing to obtain pepper powder;
(2)将步骤(1)所得的辣椒粉末置于锥形瓶中，加入质量分数为70％的乙醇溶液浸泡0.5-1h后，用微波250W提取1.0-1.5h，旋转蒸发得辣椒素粗提物；(2) Place the capsicum powder obtained in step (1) in an Erlenmeyer flask, add a mass fraction of 70% ethanol solution to soak for 0.5-1h, extract with microwave 250W for 1.0-1.5h, and rotary evaporate to obtain capsaicin crude extraction thing;
(3)取D101大孔树脂，用质量分数为95％的乙醇浸泡24-26h后，采用湿法装柱；用乙醇冲洗树脂，直到流出液变得澄清无杂质；再用纯化水冲洗树脂，直到冲洗液无乙醇气味；用3～5BV的质量分数为10％的盐酸冲洗，浸泡3.0-4.0h；用纯化水冲洗，直到流出液的PH值为5～7；用3～5BV的质量分数为7％的氢氧化钠冲洗，浸泡3.0-4.0h，用纯化水冲洗，直到流出液的PH值变为5～7，得到处理完毕的树脂；(3) Take D101 macroporous resin, soak it in ethanol with a mass fraction of 95% for 24-26h, and then pack it in a wet method; rinse the resin with ethanol until the effluent becomes clear and free of impurities; then rinse the resin with purified water, Until the rinse solution has no ethanol smell; rinse with 3-5BV of 10% hydrochloric acid and soak for 3.0-4.0h; rinse with purified water until the pH value of the effluent is 5-7; use 3-5BV of the mass fraction Rinse with 7% sodium hydroxide, soak for 3.0-4.0h, rinse with purified water until the pH value of the effluent becomes 5-7, and the treated resin is obtained;
(4)将步骤(2)所得的辣椒素粗提物过滤后，沿壁缓慢倒入步骤(3)所得的处理完毕的树脂，待吸附平衡后用8BV的质量分数为70％的乙醇以1mL/min的速度洗脱，收集洗脱液旋转蒸发浓缩，冷冻干燥，即得辣椒素提取物。(4) After filtering the capsaicin crude extract obtained in step (2), slowly pour the processed resin obtained in step (3) along the wall, and after the adsorption equilibrium, use 8BV of mass fraction to be 70% ethanol with 1mL /min speed elution, the collected eluate is concentrated by rotary evaporation, and freeze-dried to obtain the capsaicin extract.
实施例1Example 1
一种含有辣椒素提取物的口含制品，包括以下重量份组分：A buccal product containing capsaicin extract, comprising the following components in parts by weight:
辣椒素提取物15份，尼古丁盐10份，保湿剂10份，甜味剂5份，凉味剂0.5份，抗氧化剂1份，香精10份，微晶纤维素40份，麦芽糖醇15份，阿拉伯树胶溶液30份，山梨酸钾0.05份，碳酸钙1份，碳酸氢钠3份。15 parts of capsaicin extract, 10 parts of nicotine salt, 10 parts of humectant, 5 parts of sweetener, 0.5 part of cooling agent, 1 part of antioxidant, 10 parts of essence, 40 parts of microcrystalline cellulose, 15 parts of maltitol, 30 parts of gum arabic solution, 0.05 parts of potassium sorbate, 1 part of calcium carbonate, and 3 parts of sodium bicarbonate.
其中，所述的尼古丁盐为乳酸尼古丁盐，所述的保湿剂为丙二醇，所述的甜味剂为安赛蜜，所述的凉味剂为WS-3，所述的抗氧化剂为维生素C，所述的香精为柠檬香精。Wherein, the nicotine salt is lactic acid nicotine salt, the moisturizing agent is propylene glycol, the sweetener is acesulfame potassium, the cooling agent is WS-3, and the antioxidant is vitamin C , the essence is lemon essence.
实施例1的辣椒素提取物的制备方法，包括以下步骤The preparation method of the capsaicin extract of embodiment 1, comprises the following steps
(1)新鲜辣椒去籽、去梗，置于55℃的恒温干燥箱中烘干，粉碎后过60目筛，得辣椒粉末；(1) Remove seeds and stems from fresh peppers, place them in a constant temperature drying oven at 55° C. for drying, and pass through a 60-mesh sieve after crushing to obtain pepper powder;
(2)将步骤(1)所得的辣椒粉末置于锥形瓶中，加入质量分数为70％的乙醇溶液浸泡0.5h后，用微波250W提取1.0h，旋转蒸发得辣椒素粗提物；(2) Place the capsicum powder obtained in step (1) in an Erlenmeyer flask, add a mass fraction of 70% ethanol solution to soak for 0.5 h, extract with microwave 250W for 1.0 h, and rotary evaporate to obtain capsaicin crude extract;
(3)取D101大孔树脂，用质量分数为95％的乙醇浸泡24h后，采用湿法装柱；用乙醇冲洗树脂，直到流出液变得澄清无杂质；再用纯化水冲洗树脂，直到冲洗液无乙醇气味；用3BV(BV：树脂床体积)的质量分数为10％的盐酸冲洗，浸泡3.0h；用纯化水冲洗，直到流出液的PH值为6；用3BV的质量分数为7％的氢氧化钠冲洗，浸泡3.0h，用纯化水冲洗，直到流出液的PH值变为6，得到处理完毕的树脂；(3) Take D101 macroporous resin, soak it with 95% ethanol for 24 hours, and then pack it by wet method; rinse the resin with ethanol until the effluent becomes clear and free of impurities; then rinse the resin with purified water until it is rinsed The liquid has no ethanol odor; rinse with 10% hydrochloric acid with a mass fraction of 3BV (BV: resin bed volume), and soak for 3.0h; rinse with purified water until the pH value of the effluent is 6; use 7% with a mass fraction of 3BV Rinse with sodium hydroxide, soak for 3.0h, and rinse with purified water until the pH value of the effluent becomes 6 to obtain the processed resin;
(4)将步骤(2)所得的辣椒素粗提物过滤后，沿壁缓慢倒入步骤(3)所得的处理完毕的树脂，待吸附平衡后用8BV的质量分数为70％的乙醇以1mL/min的速度洗脱，收集洗脱液旋转蒸发浓缩，冷冻干燥，即得辣椒素提取物。(4) After filtering the capsaicin crude extract obtained in step (2), slowly pour the processed resin obtained in step (3) along the wall, and after the adsorption equilibrium, use 8BV of mass fraction to be 70% ethanol with 1mL /min speed elution, the collected eluate is concentrated by rotary evaporation, and freeze-dried to obtain the capsaicin extract.
实施例2-3、对比例2-3的辣椒素提取物的制备方法与实施例1相同。The preparation method of the capsaicin extract of Example 2-3 and Comparative Example 2-3 is the same as that of Example 1.
实施例1的含有辣椒素提取物的口含制品的制备方法，包括以下步骤：The preparation method of the oral product containing capsaicin extract of embodiment 1, comprises the following steps:
S1.按照各重量份精确称取各组分，取微晶纤维素、麦芽糖醇、甜味剂、凉味剂、抗氧化剂、山梨酸钾、碳酸钙、碳酸氢钠置于烧杯中，混合搅拌均匀，得到混合物；S1. Accurately weigh each component according to each weight part, take microcrystalline cellulose, maltitol, sweetener, cooling agent, antioxidant, potassium sorbate, calcium carbonate, sodium bicarbonate and place in a beaker, mix and stir Homogeneously, a mixture is obtained;
S2.往步骤S1所得的混合物中加入阿拉伯树胶溶液和保湿剂，再次搅拌均匀，选用60目筛网进行过筛处理，收集过筛后的粉末；S2. Add gum arabic solution and humectant to the mixture obtained in step S1, stir evenly again, select a 60-mesh sieve to sieve, and collect the sieved powder;
S3.往步骤S2所得的粉末中加入尼古丁盐、辣椒素提取物、香精，搅拌直至混合均匀；S3. Add nicotine salt, capsaicin extract, and essence to the powder obtained in step S2, and stir until evenly mixed;
S4.将步骤S3所得的产物进行分装，每份为0.5g，用无纺布包装成细长条型，封口机封口，灭菌，即得含有辣椒素提取物的口含制品。S4. Subpackage the product obtained in step S3, each portion is 0.5g, pack it into a long and thin strip with a non-woven fabric, seal it with a sealing machine, and sterilize it to obtain the oral product containing capsaicin extract.
实施例2-3、对比例2-3的含有辣椒素提取物的口含制品的制备方法、对比例1的口含制品的制备方法与实施例1相同。The preparation method of the oral product containing capsaicin extract of Example 2-3, Comparative Example 2-3, and the preparation method of the oral product of Comparative Example 1 are the same as that of Example 1.
实施例2Example 2
一种含有辣椒素提取物的口含制品，包括以下重量份组分：A buccal product containing capsaicin extract, comprising the following components in parts by weight:
辣椒素提取物20份，尼古丁盐15份，保湿剂10份，甜味剂5份，凉味剂0.5份，抗氧化剂1份，香精10份，微晶纤维素40份，麦芽糖醇15份，阿拉伯树胶溶液30份，山梨酸钾0.05份，碳酸钙1份，碳酸氢钠3份。20 parts of capsaicin extract, 15 parts of nicotine salt, 10 parts of humectant, 5 parts of sweetener, 0.5 part of cooling agent, 1 part of antioxidant, 10 parts of essence, 40 parts of microcrystalline cellulose, 15 parts of maltitol, 30 parts of gum arabic solution, 0.05 parts of potassium sorbate, 1 part of calcium carbonate, and 3 parts of sodium bicarbonate.
其中，所述的尼古丁盐为酒石酸-尼古丁盐，所述的保湿剂为丙三醇，所述的甜味剂为安赛蜜，所述的凉味剂为WS-3，所述的抗氧化剂为维生素E，所述的香精为柠檬香精。Wherein, the nicotine salt is tartaric acid-nicotine salt, the moisturizing agent is glycerin, the sweetener is acesulfame potassium, the cooling agent is WS-3, and the antioxidant It is vitamin E, and the essence is lemon essence.
实施例3Example 3
一种含有辣椒素提取物的口含制品，包括以下重量份组分：A buccal product containing capsaicin extract, comprising the following components in parts by weight:
辣椒素提取物5份，尼古丁盐5份，保湿剂10份，甜味剂5份，凉味剂0.5份，抗氧化剂1份，香精10份，微晶纤维素40份，麦芽糖醇15份，阿拉伯树胶溶液30份，山梨酸钾0.05份，碳酸钙1份，碳酸氢钠3份。5 parts of capsaicin extract, 5 parts of nicotine salt, 10 parts of humectant, 5 parts of sweetener, 0.5 part of cooling agent, 1 part of antioxidant, 10 parts of essence, 40 parts of microcrystalline cellulose, 15 parts of maltitol, 30 parts of gum arabic solution, 0.05 parts of potassium sorbate, 1 part of calcium carbonate, and 3 parts of sodium bicarbonate.
其中，所述的尼古丁盐为乳酸尼古丁盐，所述的保湿剂为丙二醇，所述的甜味剂为安赛蜜，所述的凉味剂为WS-3，所述的抗氧化剂为维生素C，所述的香精为柠檬香精。Wherein, the nicotine salt is lactic acid nicotine salt, the moisturizing agent is propylene glycol, the sweetener is acesulfame potassium, the cooling agent is WS-3, and the antioxidant is vitamin C , the essence is lemon essence.
对比例1Comparative example 1
一种口含制品，包括以下重量份组分：A mouth product, comprising the following components in parts by weight:
尼古丁盐10份，保湿剂10份，甜味剂5份，凉味剂0.5份，抗氧化剂1份，香精10份，微晶纤维素40份，麦芽糖醇15份，阿拉伯树胶溶液30份，山梨酸钾0.05份，碳酸钙1份，碳酸氢钠3份。10 parts of nicotine salt, 10 parts of humectant, 5 parts of sweetener, 0.5 part of cooling agent, 1 part of antioxidant, 10 parts of essence, 40 parts of microcrystalline cellulose, 15 parts of maltitol, 30 parts of gum arabic solution, sorbic acid 0.05 parts of potassium carbonate, 1 part of calcium carbonate, and 3 parts of sodium bicarbonate.
其中，所述的尼古丁盐为乳酸尼古丁盐，所述的保湿剂为丙二醇，所述的甜味剂为安赛蜜，所述的凉味剂为WS-3，所述的抗氧化剂为维生素C，所述的香精为柠檬香精。Wherein, the nicotine salt is lactic acid nicotine salt, the moisturizing agent is propylene glycol, the sweetener is acesulfame potassium, the cooling agent is WS-3, and the antioxidant is vitamin C , the essence is lemon essence.
对比例2Comparative example 2
一种含有辣椒素提取物的口含制品，包括以下重量份组分：A buccal product containing capsaicin extract, comprising the following components in parts by weight:
辣椒素提取物25份，尼古丁盐10份，保湿剂10份，甜味剂5份，凉味剂0.5份，抗氧化剂1份，香精10份，微晶纤维素40份，麦芽糖醇15份，阿拉伯树胶溶液30份，山梨酸钾0.05份，碳酸钙1份，碳酸氢钠3份。25 parts of capsaicin extract, 10 parts of nicotine salt, 10 parts of humectant, 5 parts of sweetener, 0.5 part of cooling agent, 1 part of antioxidant, 10 parts of essence, 40 parts of microcrystalline cellulose, 15 parts of maltitol, 30 parts of gum arabic solution, 0.05 parts of potassium sorbate, 1 part of calcium carbonate, and 3 parts of sodium bicarbonate.
其中，所述的尼古丁盐为乳酸尼古丁盐，所述的保湿剂为丙二醇，所述的甜味剂为安赛蜜，所述的凉味剂为WS-3，所述的抗氧化剂为维生素C，所述的香精为柠檬香精。Wherein, the nicotine salt is lactic acid nicotine salt, the moisturizing agent is propylene glycol, the sweetener is acesulfame potassium, the cooling agent is WS-3, and the antioxidant is vitamin C , the essence is lemon essence.
对比例3Comparative example 3
一种含有辣椒素提取物的口含制品，包括以下重量份组分：A buccal product containing capsaicin extract, comprising the following components in parts by weight:
辣椒素提取物2份，尼古丁盐20份，保湿剂10份，甜味剂5份，凉味剂0.5份，抗氧化剂1份，香精10份，微晶纤维素40份，麦芽糖醇15份，阿拉伯树胶溶液30份，山梨酸钾0.05份，碳酸钙1份，碳酸氢钠3份。2 parts of capsaicin extract, 20 parts of nicotine salt, 10 parts of humectant, 5 parts of sweetener, 0.5 part of cooling agent, 1 part of antioxidant, 10 parts of essence, 40 parts of microcrystalline cellulose, 15 parts of maltitol, 30 parts of gum arabic solution, 0.05 parts of potassium sorbate, 1 part of calcium carbonate, and 3 parts of sodium bicarbonate.
其中，所述的尼古丁盐为乳酸尼古丁盐，所述的保湿剂为丙二醇，所述的甜味剂为安赛蜜，所述的凉味剂为WS-3，所述的抗氧化剂为维生素C，所述的香精为柠檬香精。Wherein, the nicotine salt is lactic acid nicotine salt, the moisturizing agent is propylene glycol, the sweetener is acesulfame potassium, the cooling agent is WS-3, and the antioxidant is vitamin C , the essence is lemon essence.
感官评价Sensory evaluation
取口含制品置于上嘴唇与牙龈之间，感受口含制品的香味、口感并进行评价。每份口含制品品尝5min，随后吐出。口含制品的感官评价测试，包括香味、凉度、甜度、舒适度、上头感、释放速率、刺激性(口腔、喉咙)7个项目，具体评分标准与细则见下表1。Take the oral product and place it between the upper lip and the gums, feel and evaluate the fragrance and taste of the oral product. Each buccal product was tasted for 5 minutes and then spit out. The sensory evaluation test of oral products includes 7 items of fragrance, coolness, sweetness, comfort, top feeling, release rate, and irritation (mouth, throat). The specific scoring standards and details are shown in Table 1 below.
表1口含制品的感官评价测试评分标准与细则Table 1 Scoring criteria and detailed rules for sensory evaluation test of oral products
将实施例1-3、对比例2-3的含有辣椒素提取物的口含制品以及对比例1的口含制品进行感官测试，测试结果如下表2所示：The oral products containing capsaicin extract of Examples 1-3, Comparative Examples 2-3 and the oral products of Comparative Example 1 were subjected to a sensory test, and the test results are shown in Table 2 below:
表2实施例1-3、对比例2-3的含有辣椒素提取物的口含制品以及对比例1的口含制品的感官测试结果Table 2 The sensory test results of the oral product containing capsaicin extract of Example 1-3, Comparative Example 2-3 and the oral product of Comparative Example 1
由表2测试结果可知，采用本发明实施例的组分制备而成的含有辣椒素提取物的口含制品上头感、刺激性强并且释放速率快。口含制品中不含辣椒素提取物(对比例1)或辣椒素提取物的含量不在本发明范围内(对比例2)，其刺激性较弱，上头感和释放速率不如采用本发明实施例的组分制备而成的含有辣椒素提取物的口含制品。此外，对比例2的含有辣椒素提取物的口含制品中加入辣椒素提取物含量过高，导致产品过于呛刺，辛辣刺激感难以接受；对比例3的含有辣椒素提取物的口含制品中辣椒素提取物含量与尼古丁盐含量不在本发明范围内，导致产品虽有上头感和一些刺激感，但是香味不够浓郁，口感不佳。From the test results in Table 2, it can be seen that the oral product containing capsaicin extract prepared by using the components of the embodiment of the present invention has a strong sense of taste, strong irritation and fast release rate. Oral preparations do not contain capsaicin extract (comparative example 1) or the content of capsaicin extract is not within the scope of the present invention (comparative example 2), its pungency is weaker, and the sensation on the head and release rate are not as good as using the embodiment of the present invention Oral products containing capsaicin extract prepared from the ingredients. In addition, the content of capsaicin extract added to the oral product containing capsaicin extract in Comparative Example 2 was too high, resulting in the product being too pungent and unacceptably spicy; the oral product containing capsaicin extract in Comparative Example 3 The content of the capsaicin extract and the nicotine salt in the product are not within the scope of the present invention, resulting in a product with a sense of topping and some irritation, but the fragrance is not strong enough and the taste is not good.
综上所述，与现有技术相比，本发明的含有辣椒素提取物的口含制品及其制备方法，通过将辣椒加入乙醇浸泡后微波提取，得到提取液后旋转蒸发浓缩，浓缩液过D-101大孔树脂吸附分离从而进一步纯化，得到辣椒素提取物。将辣椒素提取物作为辅料之一添加到口含制品的制备过程中，最终得到一种含有辣椒素提取物的口含制品。本发明通过从辣椒中提取、纯化得到辣椒素提取物，将辣椒素提取物作为辅料之一加入到口含制品的制备过程中，从而得到一种含有辣椒素提取物的口含制品，能够有效弥补以往口含制品刺激性弱、辣感低的缺陷，避免通过调节口含制品碱性过高从而导致尼古丁氧化的问题。In summary, compared with the prior art, the oral product containing capsaicin extract and the preparation method thereof of the present invention, after soaking capsicum in ethanol and extracting with microwaves, obtain the extract and concentrate it by rotary evaporation. D-101 macroporous resin is adsorbed and separated for further purification to obtain capsaicin extract. The capsaicin extract is added to the preparation process of the oral product as one of the auxiliary materials, and finally a oral product containing the capsaicin extract is obtained. The present invention obtains capsaicin extract by extracting and purifying capsaicin, and adds capsaicin extract as one of auxiliary materials into the preparation process of oral products, thereby obtaining a oral product containing capsaicin extract, which can effectively It makes up for the defects of weak irritation and low spicy feeling of oral products in the past, and avoids the problem of nicotine oxidation caused by adjusting the alkalinity of oral products.
以上所述，仅为本发明的具体实施方式，但本发明的保护范围并不局限于此，任何熟悉本技术领域的技术人员在本发明揭露的技术范围内，可轻易想到各种等效的修改或替换，这些修改或替换都应涵盖在本发明的保护范围之内。因此，本发明的保护范围应以权利要求的保护范围为准。The above is only a specific embodiment of the present invention, but the protection scope of the present invention is not limited thereto. Any person familiar with the technical field can easily think of various equivalents within the technical scope disclosed in the present invention. Modifications or replacements shall all fall within the protection scope of the present invention. Therefore, the protection scope of the present invention should be based on the protection scope of the claims.
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| CN202310711595.0ACN116570027A (en) | 2023-06-15 | 2023-06-15 | Buccal product containing capsaicin extract and its preparation method |
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| CN202310711595.0ACN116570027A (en) | 2023-06-15 | 2023-06-15 | Buccal product containing capsaicin extract and its preparation method |
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