CN116430042A - A simple nasopharyngeal swab antigen detection device and detection method - Google Patents

Abstract

The invention discloses a simple nasopharyngeal swab antigen detection device and a detection method, belonging to the technical field of biological detection; the device comprises a sample synthesis cylinder, a supporting body, antigen detection test paper and a liquid storage tube, wherein the sample synthesis cylinder is provided with a cylinder cover, and a sample injection hole and a connecting hole are formed in the cylinder cover; the bearing body is arranged in the connecting hole and can move along the depth direction of the connecting hole, and a first accommodating groove and a second accommodating groove are formed in the bearing body; the antigen detection test paper is arranged in the second accommodating groove, one end of the antigen detection test paper, which is close to the sample synthesis barrel, is provided with an isolation film, the isolation film is positioned at the opening of the second accommodating groove, the bottom of the inner barrel of the sample synthesis barrel is provided with a sharp bulge, and the isolation film is positioned below the isolation film; one end of the liquid storage tube, which is arranged in the sample synthesis cylinder, is provided with a cotton ball, the other end of the liquid storage tube is provided with a liquid inlet control structure, and the liquid storage tube is filled with pyrolysis liquid; the invention can effectively solve the problem that the accurate result is not detected and the virus is diffused because the extracted liquid is easily dripped outside the sample titration area.

Description

Translated fromChinese

一种简易鼻咽拭子抗原检测装置及检测方法A simple nasopharyngeal swab antigen detection device and detection method

技术领域technical field

本发明涉及生物检测技术领域，具体是一种简易鼻咽拭子抗原检测装置及检测方法。The invention relates to the technical field of biological detection, in particular to a simple nasopharyngeal swab antigen detection device and detection method.

背景技术Background technique

冠状病毒是一类具有囊膜，基因组为线性单股正链的NA病毒，是自然界广泛存在的一大类病毒，主要通过呼吸道飞沫、呼吸道分泌物和直接接触传播。Coronavirus is a type of NA virus with an envelope and a linear single-stranded positive strand genome. It is a large class of viruses that exist widely in nature and is mainly transmitted through respiratory droplets, respiratory secretions and direct contact.

新型冠状病毒抗原检测试剂盒是现阶段为止主要的检测手段之一，其原理主要是利用抗原与抗体特异性结合的原理，可通过抗体检测抗原的存在，从而证明样本中有新冠病毒，目前市面上基于该原理在售的新型冠状病毒检测试剂盒由多种，现有市面上在售的型冠状病毒检测试剂盒均是人工手持一次性采样器，采样后需首先放入裂解液制备提取液再将提取液滴到抗原检测试剂卡的样本滴定区，由于抗原检测试剂卡的样本滴定区较小，当检测人员出现手臂出现轻微抖动便有可能将提取液滴到样本滴定区外，导致检测不出正确的结果，并且滴到样本滴定区以外的提取液中可能含有病毒，病毒容易出现扩散。与此同时，使用过的采样棉棒做为医疗废物，处理操作不当也会导致二次污染。The new coronavirus antigen detection kit is one of the main detection methods at this stage. Its principle is mainly to use the principle of specific combination of antigen and antibody, and the presence of antigen can be detected by antibody, so as to prove that there is new coronavirus in the sample. It is currently on the market Based on this principle, there are many types of novel coronavirus detection kits on sale. The existing novel coronavirus detection kits on the market are all hand-held disposable samplers. Then drop the extraction liquid into the sample titration area of the antigen detection reagent card. Since the sample titration area of the antigen detection reagent card is small, when the inspector has a slight shaking of the arm, the extraction liquid may be dropped outside the sample titration area, resulting in detection No correct results can be obtained, and the extract dripped outside the titration area of the sample may contain viruses, and the viruses are prone to spread. At the same time, used sampling cotton swabs are used as medical waste, and improper handling will also lead to secondary pollution.

以上背景技术内容的公开仅用于辅助理解本发明的构思及技术方案，其并不必然属于本专利申请的现有技术，在没有明确的证据表明上述内容在本专利申请的申请日已经公开的情况下，上述背景技术不应当用于评价本申请的新颖性和创造性。The disclosure of the above background technical content is only used to assist in understanding the concept and technical solution of the present invention, and it does not necessarily belong to the prior art of this patent application. If there is no clear evidence that the above content has been disclosed on the filing date of this patent application In some cases, the above background technology should not be used to evaluate the novelty and inventiveness of this application.

发明内容Contents of the invention

本公开的目的之一是提供一种能够克服现有技术中至少一个缺陷的简易鼻咽拭子抗原检测装置。One of the purposes of the present disclosure is to provide a simple nasopharyngeal swab antigen detection device capable of overcoming at least one defect in the prior art.

为解决上述技术问题，本申请实施例公开了如下技术方案：In order to solve the above technical problems, the embodiment of the present application discloses the following technical solutions:

一种简易鼻咽拭子抗原检测装置，包括：A simple nasopharyngeal swab antigen detection device, comprising:

样本合成筒，所述样本合成筒配置有筒盖，所述筒盖上开设有进样孔、连接孔；A sample synthesis cylinder, the sample synthesis cylinder is equipped with a cylinder cover, and a sample injection hole and a connection hole are opened on the cylinder cover;

承载体，所述承载体安装在所述连接孔内，可沿连接孔的孔深方向移动，所述承载体上开设有第一容置槽、第二容置槽；A carrier, the carrier is installed in the connection hole and can move along the depth direction of the connection hole, and the carrier is provided with a first accommodation groove and a second accommodation groove;

抗原检测试纸，所述抗原检测试纸设置在所述第二容置槽内，所述抗原检测试纸靠近所述样本合成筒的一端设置有隔离薄膜，所述隔离薄膜位于第二容置槽的开口处，所述样本合成筒的内部筒底上设置有尖锐凸起，位于隔离薄膜下方；Antigen detection test paper, the antigen detection test paper is arranged in the second storage tank, the end of the antigen detection test paper close to the sample synthesis cylinder is provided with an isolation film, and the isolation film is located at the opening of the second storage tank , the inner cylinder bottom of the sample synthesis cylinder is provided with a sharp protrusion, which is located under the isolation film;

储液管，所述储液管置于所述样本合成筒内的一端设置有棉球，另一端设置有进液控制结构，所述储液管内盛有裂解液。A liquid storage tube, one end of the liquid storage tube placed in the sample synthesis cylinder is provided with a cotton ball, and the other end is provided with a liquid inlet control structure, and the liquid storage tube contains a lysate.

优选地，本申请实施例还公开了：所述进样孔配置有橡胶塞。Preferably, the embodiment of the present application also discloses that: the sample injection hole is equipped with a rubber stopper.

优选地，本申请实施例还公开了：所述简易鼻咽拭子抗原检测装置还包括：采样棉棒，当采样棉棒采样完毕时，通过进样孔延伸进所述样本合成筒内。Preferably, the embodiment of the present application also discloses that: the simple nasopharyngeal swab antigen detection device further includes: a sampling cotton swab, which extends into the sample synthesis cylinder through the sampling hole when the sampling cotton swab is finished sampling.

优选地，本申请实施例还公开了：所述承载体的底端为柱状体，所述柱状体上设置有外螺纹，所述连接孔的孔壁上设置有与所述柱状体上的外螺纹相配合的内螺纹。Preferably, the embodiment of the present application also discloses that: the bottom end of the carrier is a columnar body, the columnar body is provided with external threads, and the hole wall of the connecting hole is provided with an external screw thread on the columnar body. Thread mating internal thread.

优选地，本申请实施例还公开了：所述柱状体上还设置有第一限位环、第二限位环，所述第二限位环相较于所述第一限位环更远离所述样本合成筒，所述第一限位环的制作材料为脆性材料。Preferably, the embodiment of the present application also discloses: the columnar body is also provided with a first limiting ring and a second limiting ring, and the second limiting ring is farther away from the first limiting ring than the first limiting ring. In the sample synthesis cylinder, the material of the first limiting ring is a brittle material.

优选地，本申请实施例还公开了：所述进液控制结构为密封盖。Preferably, the embodiment of the present application also discloses that: the liquid inflow control structure is a sealing cover.

优选地，本申请实施例还公开了：所述储液管远离所述样本合成筒的一端密封，所述进液控制结构为：设置在所述储液管外壁上的折断刻痕。Preferably, the embodiment of the present application also discloses that: the end of the liquid storage tube away from the sample synthesis cylinder is sealed, and the liquid inlet control structure is: a breaking score provided on the outer wall of the liquid storage tube.

优选地，本申请实施例还公开了：所述样本合成筒的底壁采用硬性材料制作而成，所述样本合成筒的周向侧壁的中间部位采用软性材料制作而成。Preferably, the embodiment of the present application also discloses that: the bottom wall of the sample synthesis cylinder is made of hard material, and the middle part of the circumferential side wall of the sample synthesis cylinder is made of soft material.

优选地，本申请实施例还公开了：所述样本合成筒采用透明材料制作而成。Preferably, the embodiment of the present application also discloses that: the sample synthesis cylinder is made of transparent material.

一种采用上述简易鼻咽拭子抗原检测装置的检测方法，包括以下步骤：A detection method using the above-mentioned simple nasopharyngeal swab antigen detection device, comprising the following steps:

S1将进行鼻腔采样后的采样棉棒，从桶盖的进样孔进入样本合成筒内部；利用进液控制结构使裂解液从储液管内流出落入到样本合成筒内；S1 enters the sampling cotton swab after nasal cavity sampling into the sample synthesis cylinder from the sampling hole of the barrel cover; uses the liquid inlet control structure to make the lysate flow out of the liquid storage tube and fall into the sample synthesis cylinder;

S2将承载体的柱状体拧进连接孔内，拧至抵触第一限位环的位置，然后挤压样本合成筒的软壁，使储液管的棉球上的裂解液充分落入到样本合成筒内部；S2 Screw the columnar body of the carrier into the connection hole until it touches the first limit ring, and then squeeze the soft wall of the sample synthesis tube, so that the lysate on the cotton ball of the liquid storage tube fully falls into the sample Inside the synthesis cylinder;

S3将承载体的柱状体拧至抵触第二限位环的位置，使样本合成筒内部底壁上的尖锐凸起将隔离薄膜破坏，使样本合成筒内部的裂解液充分与抗原检测试纸接触完成检测。S3 Screw the columnar body of the carrier to the position where it interferes with the second limit ring, so that the sharp protrusions on the inner bottom wall of the sample synthesis cylinder destroy the isolation film, so that the lysate inside the sample synthesis cylinder is fully in contact with the antigen detection test paper to complete detection.

本申请实施例中提供的一个或多个技术方案，至少具有如下技术效果或优点：One or more technical solutions provided in the embodiments of this application have at least the following technical effects or advantages:

本申请实施例中,可通过采样棉棒进行鼻腔采样，并将采样后的采样棉棒从桶盖的进样孔进入样本合成筒内部；利用进液控制结构使裂解液从储液管内流出落入到样本合成筒内。然后将承载体的柱状体拧进连接孔内，拧至抵触第一限位环的位置，然后挤压软壁，使储液管的棉球上的裂解液充分落入到样本合成筒内部。再将承载体的柱状体拧至抵触第二限位环的位置，使样本合成筒内部底壁上的尖锐凸起将隔离薄膜破坏，使样本合成筒内部的裂解液充分与抗原检测试纸接触完成检测。因此，无需手动将将提取液滴到样本滴定区上，可以有效解决由于抗原检测试剂卡的样本滴定区较小，当检测人员出现手臂出现轻微抖动便有可能将提取液滴到样本滴定区外，导致检测不出正确的结果，使得病毒容易出现扩散的问题，此外采样棉棒还可以不用取出，即可进行检测，因此可以有效防止从裂解液中拿出的采样棉棒使其他物品受到污染。In the embodiment of the present application, nasal cavity sampling can be carried out by sampling cotton swabs, and the sampled sampling cotton swabs are entered into the sample synthesis cylinder from the sampling hole of the barrel cover; into the sample synthesis tube. Then screw the columnar body of the carrier into the connection hole until it touches the position of the first stop ring, and then squeeze the soft wall so that the lysate on the cotton ball of the liquid storage tube fully falls into the inside of the sample synthesis cylinder. Then screw the columnar body of the carrier to the position where it interferes with the second limit ring, so that the sharp protrusion on the inner bottom wall of the sample synthesis tube will destroy the isolation film, so that the lysate inside the sample synthesis tube can fully contact the antigen detection test paper. detection. Therefore, there is no need to manually drop the extraction liquid onto the sample titration area, which can effectively solve the problem that due to the small sample titration area of the antigen detection reagent card, when the tester shakes the arm slightly, the extraction liquid may be dropped outside the sample titration area , leading to the inability to detect the correct results, which makes the virus prone to spread. In addition, the sampling cotton swab can be tested without taking it out, so it can effectively prevent the sampling cotton swab taken out from the lysate from contaminating other items. .

综上所述，本发明相较现有方法操作更加简便，同时有效解决容易将提取液滴到样本滴定区外，导致检测不出正确结果，最后本发明将各种检测试剂集于样本合成筒内，有效避免了医疗废物潜在的二次污染。In summary, the present invention is more convenient to operate than the existing method, and at the same time, it effectively solves the problem that it is easy to drop the extraction liquid outside the sample titration area, resulting in no correct detection results. Finally, the present invention integrates various detection reagents into the sample synthesis tube It effectively avoids the potential secondary pollution of medical waste.

本申请实施例中,进样孔配置有橡胶塞，可有效保持样本合成筒内部不被外部污染。In the embodiment of the present application, the sample injection hole is equipped with a rubber stopper, which can effectively keep the inside of the sample synthesis cylinder from being polluted by the outside.

本申请实施例中,样本合成筒采用透明材料制作而成，方便观察样本合成筒的内部，进行取样操作。In the embodiment of the present application, the sample synthesis cylinder is made of transparent material, which is convenient for observing the inside of the sample synthesis cylinder for sampling operation.

附图说明Description of drawings

为了更清楚地说明本发明实施例或现有技术中的技术方案，下面将对实施例或现有技术描述中所需要使用的附图作简单地介绍，应当理解的是，在所有附图中，相同的附图标记表示相同的元件。在附图中，为清楚起见，方便理解，某些特征的尺寸可以进行变形。In order to more clearly illustrate the technical solutions in the embodiments of the present invention or the prior art, the following will briefly introduce the drawings that need to be used in the description of the embodiments or the prior art. It should be understood that in all the drawings , the same reference numerals denote the same elements. In the drawings, for clarity and understanding, the dimensions of some features may be deformed.

图1为本发明实施例的一种简易鼻咽拭子抗原检测装置的结构示意图；Fig. 1 is a schematic structural view of a simple nasopharyngeal swab antigen detection device according to an embodiment of the present invention;

图2为本发明实施例中承载体的结构示意图；FIG. 2 is a schematic structural view of a carrier in an embodiment of the present invention;

图3为本发明实施例中承载体的俯视图；Fig. 3 is a top view of the carrier in the embodiment of the present invention;

图4为图3中B-B剖视图。Fig. 4 is a cross-sectional view of B-B in Fig. 3 .

图5为本发明实施例中样本合成筒的结构示意图；5 is a schematic structural view of the sample synthesis cylinder in the embodiment of the present invention;

图6为本发明实施例中样本合成筒的俯视结构示意图；Fig. 6 is a schematic top view of the sample synthesis tube in the embodiment of the present invention;

图7为图6中A-A剖视图。Fig. 7 is a sectional view of A-A in Fig. 6 .

附图标记说明：Explanation of reference signs:

10、样本合成筒；11、筒盖；111、进样孔；112、连接孔；12、尖锐凸起；20、承载体；201、第一容置槽；202、第二容置槽；203、隔离薄膜；204、柱状体；205、第一限位环；206、第二限位环；30、抗原检测试纸；31、储液管；311、密封盖；312、棉球。10. Sample synthesis tube; 11. Tube cover; 111. Injection hole; 112. Connection hole; 12. Sharp protrusion; 20. Carrier; 201. First storage tank; 202. Second storage tank; 203 , isolation film; 204, columnar body; 205, first limit ring; 206, second limit ring; 30, antigen detection test paper; 31, liquid storage tube; 311, sealing cap; 312, cotton ball.

具体实施方式Detailed ways

下面将结合本发明实施例中的附图，对本发明实施例中的技术方案进行清楚、完整地描述，显然，所描述的实施例仅是本发明一部分实施例，而不是全部的实施例。基于本发明中的实施例，本领域普通技术人员在没有做出创造性劳动前提下所获得的所有其他实施例，都属于本发明保护的范围。The following will clearly and completely describe the technical solutions in the embodiments of the present invention with reference to the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only some of the embodiments of the present invention, not all of them. Based on the embodiments of the present invention, all other embodiments obtained by persons of ordinary skill in the art without making creative efforts belong to the protection scope of the present invention.

需要说明的是，在本发明的描述中，术语“中”、“上”、“下”、“横”、“内”等指示的方向或位置关系的术语是基于附图所示的方向或位置关系，这仅仅是为了便于描述，而不是指示或暗示所述装置或元件必须具有特定的方位、以特定的方位构造和操作，因此不能理解为对本发明的限制。It should be noted that, in the description of the present invention, terms such as "middle", "upper", "lower", "horizontal", "inner" and other indicated directions or positional relationships are based on the directions or positional relationships shown in the drawings. The positional relationship, which is just for convenience of description, does not indicate or imply that the device or element must have a specific orientation, be constructed and operated in a specific orientation, and thus should not be construed as limiting the present invention.

此外，还需要说明的是，在本发明的描述中，除非另有明确的规定和限定，术语“设置”、“安装”、“相连”、“连接”应做广义理解，例如，可以是固定连接，也可以是可拆卸连接，或一体地连接；可以是机械连接；可以是直接相连，也可以通过中间媒介间接相连，可以是两个元件内部的连通。对于本领域技术人员而言，可根据具体情况理解上述术语在本发明中的具体含义。In addition, it should be noted that, in the description of the present invention, unless otherwise specified and limited, the terms "setting", "installation", "connection" and "connection" should be interpreted in a broad sense, for example, it may be a fixed The connection can also be a detachable connection or an integral connection; it can be a mechanical connection; it can be a direct connection or an indirect connection through an intermediary, and it can be an internal communication between two components. Those skilled in the art can understand the specific meanings of the above terms in the present invention according to specific situations.

实施例：Example:

参照图1-7，本实施例公开了一种简易鼻咽拭子抗原检测装置，包括：样本合成筒10、承载体20、抗原检测试纸30、储液管31，所述样本合成筒10配置有筒盖11，所述筒盖11通过内螺纹与外螺纹的配合可拆卸的安装在所述样本合成筒10上，所述筒盖11上开设有进样孔111、连接孔112；所述承载体20安装在所述连接孔112内，可沿连接孔112的孔深方向移动，所述承载体20上开设有第一容置槽201、第二容置槽202；所述抗原检测试纸30设置在所述第二容置槽202内，所述抗原检测试纸30靠近所述样本合成筒10的一端设置有隔离薄膜203，所述隔离薄膜203位于第二容置槽202的开口处，所述样本合成筒10的内部筒底上设置有尖锐凸起12，位于隔离薄膜203下方；所述储液管31置于所述样本合成筒10内的一端设置有棉球312，另一端设置有进液控制结构，所述储液管31内盛有裂解液，需要说明的是第二容置槽202的深度方向上的横截面不一致，靠近开口处的横截面的形状为圆形，方便破坏隔离薄膜203，其他部位的横截面的形状可以根据抗原检测试纸30的横截面形状而定。Referring to Figures 1-7, this embodiment discloses a simple nasopharyngeal swab antigen detection device, including: asample synthesis tube 10, acarrier 20, an antigendetection test paper 30, and aliquid storage tube 31, and thesample synthesis tube 10 is configured There is acylinder cover 11, and thecylinder cover 11 is detachably installed on thesample synthesis cylinder 10 through the cooperation of the internal thread and the external thread, and thecylinder cover 11 is provided with asampling hole 111 and aconnection hole 112; Thecarrier 20 is installed in theconnection hole 112 and can move along the depth direction of theconnection hole 112. Thecarrier 20 is provided with afirst accommodation groove 201 and asecond accommodation groove 202; the antigendetection test paper 30 is set in thesecond storage tank 202, the end of the antigendetection test paper 30 close to thesample synthesis cylinder 10 is provided with anisolation film 203, and theisolation film 203 is located at the opening of thesecond storage tank 202, The inner cylinder bottom of thesample synthesis cylinder 10 is provided with asharp protrusion 12, which is located below theisolation film 203; one end of theliquid storage tube 31 placed in thesample synthesis cylinder 10 is provided with acotton ball 312, and the other end is provided with a There is a liquid inlet control structure, and theliquid storage tube 31 is filled with a lysate. It should be noted that the cross-sections in the depth direction of thesecond storage tank 202 are inconsistent, and the cross-section near the opening has a circular shape, which is convenient. After theisolation film 203 is destroyed, the cross-sectional shape of other parts can be determined according to the cross-sectional shape of the antigendetection test paper 30 .

所述进样孔111配置有橡胶塞或其他盖体，可有效保持样本合成筒10内部不被外部污染。Thesample injection hole 111 is equipped with a rubber stopper or other cover, which can effectively keep the inside of thesample synthesis cartridge 10 from being polluted by the outside.

所述简易鼻咽拭子抗原检测装置还包括：采样棉棒，当采样棉棒采样完毕时，通过进样孔111延伸进所述样本合成筒10内。The simple nasopharyngeal swab antigen detection device also includes: a sampling cotton swab, which extends into thesample synthesis cylinder 10 through thesampling hole 111 when the sampling cotton swab is finished sampling.

参照图3，所述承载体20的底端为柱状体204，所述柱状体204上设置有外螺纹，所述连接孔112的孔壁上设置有与所述柱状体204上的外螺纹相配合的内螺纹，使得承载体20可沿连接孔112的孔深方向移动。Referring to Fig. 3, the bottom end of thecarrier 20 is acolumnar body 204, thecolumnar body 204 is provided with external threads, and the hole wall of the connectinghole 112 is provided with The matched internal thread enables thecarrier 20 to move along the depth direction of the connectinghole 112 .

参照图3，所述柱状体204上还设置有第一限位环205、第二限位环206，所述第二限位环206相较于所述第一限位环205更远离所述样本合成筒10，所述第一限位环205的制作材料为脆性材料，当筒盖11抵触到第一限位环205，柱状体204继续朝样本合成筒10内部旋入，第一限位环205会被破坏，完全从柱状体204上脱落，不妨碍柱状体204的继续旋入。Referring to FIG. 3 , thecolumnar body 204 is also provided with a first limitingring 205 and a second limitingring 206 , and the second limitingring 206 is farther away from the In thesample synthesis cylinder 10, thefirst limit ring 205 is made of a brittle material. When thecylinder cover 11 touches thefirst limit ring 205, thecolumnar body 204 continues to screw into thesample synthesis cylinder 10, and the first limit Thering 205 will be destroyed and completely fall off from thecolumnar body 204, which does not hinder the continuous screwing of thecolumnar body 204.

参照图1和图4，在一些实施例中，所述进液控制结构为密封盖311，使用时旋开密封盖311，利用大气压与储液管31内气压差使裂解液进入另一端棉球312，需要说明的是：储液管31内存储的裂解液较多，棉球312仅会吸附一部分裂解液，大部分的裂解液会流入到样本合成筒10内。当然在其他实施例中，所述储液管31远离所述样本合成筒10的一端可实施为密封，此时，所述进液控制结构实施为：设置在所述储液管31外壁上的折断刻痕，使用时，沿着折断刻痕使储液管31的一端折断，进而使的空气进入储液管31内部，同样利用大气压与储液管31内气压差使裂解液进入另一端的棉球312内。Referring to Fig. 1 and Fig. 4, in some embodiments, the liquid inlet control structure is a sealingcap 311, unscrew thesealing cap 311 during use, and use the pressure difference between the atmospheric pressure and theliquid storage tube 31 to make the lysate enter thecotton ball 312 at the other end , it should be noted that: theliquid storage tube 31 stores a lot of lysate, thecotton ball 312 will only absorb a part of the lysate, and most of the lysate will flow into thesample synthesis tube 10 . Of course, in other embodiments, the end of theliquid storage tube 31 away from thesample synthesis cartridge 10 can be implemented as a seal. At this time, the liquid inlet control structure is implemented as: Break the notch, during use, break one end of theliquid storage tube 31 along the broken notch, and then make the air enter the inside of theliquid storage tube 31, and also use the air pressure difference between the atmospheric pressure and theliquid storage tube 31 to make the lysate enter the cotton at the other end.Ball 312 inside.

所述样本合成筒10的底壁采用硬性材料制作而成，所述样本合成筒10的周向侧壁的中间部位采用软性材料制作而成，方便将棉球312上吸附的裂解液挤压到样本合成筒10内减少浪费。The bottom wall of thesample synthesis cylinder 10 is made of a hard material, and the middle part of the circumferential side wall of thesample synthesis cylinder 10 is made of a soft material, which is convenient to squeeze the lysate adsorbed on thecotton ball 312 into thesample synthesis cartridge 10 to reduce waste.

所述样本合成筒10采用透明材料制作而成，方便观察样本合成筒10的内部，进行取样操作。Thesample synthesis tube 10 is made of transparent material, which is convenient for observing the inside of thesample synthesis tube 10 for sampling operation.

本实施例还公开了上述简易鼻咽拭子抗原检测装置的检测方法，包括以下步骤：This embodiment also discloses the detection method of the above-mentioned simple nasopharyngeal swab antigen detection device, including the following steps:

S1将进行鼻腔采样后的采样棉棒，从桶盖的进样孔111进入样本合成筒10内部；利用进液控制结构使裂解液从储液管31内流出落入到样本合成筒10内。S1 enters the sampling cotton swab after nasal cavity sampling into thesample synthesis cylinder 10 through thesampling hole 111 of the barrel lid; uses the liquid inlet control structure to make the lysate flow out from theliquid storage tube 31 and fall into thesample synthesis cylinder 10 .

S2将承载体20的柱状体204拧进连接孔112内，拧至抵触第一限位环205的位置，然后挤压样本合成筒10的软壁，使储液管31的棉球312上的裂解液充分落入到样本合成筒10内部。S2 Screw thecolumnar body 204 of thecarrier 20 into theconnection hole 112 until it touches thefirst stop ring 205, and then squeeze the soft wall of thesample synthesis tube 10 to make thecotton ball 312 of theliquid storage tube 31 The lysate fully falls into thesample synthesis cartridge 10 .

S3将承载体20的柱状体204拧至抵触第二限位环206的位置，使样本合成筒10内部底壁上的尖锐凸起12将隔离薄膜203破坏，使样本合成筒10内部的裂解液充分与抗原检测试纸30接触完成检测。S3 Screw thecolumnar body 204 of thecarrier 20 to a position against thesecond stop ring 206, so that thesharp protrusion 12 on the inner bottom wall of thesample synthesis tube 10 destroys theisolation film 203, and the lysate in thesample synthesis tube 10 Fully contact with the antigendetection test paper 30 to complete the detection.

以上对本发明及其实施方式进行了描述，这种描述没有限制性，全文中所示的也只是本发明的实施方式之一，实际的结构并不局限于此。总而言之如果本领域的普通技术人员受其启示，在不脱离本发明创造宗旨的情况下，不经创造性的设计出与该技术方案相似的结构方式及实施例，均应属于本发明的保护范围。The present invention and its implementations have been described above, but this description is not limiting, and what is shown throughout the text is only one of the implementations of the present invention, and the actual structure is not limited thereto. All in all, if a person of ordinary skill in the art is inspired by it, without departing from the inventive concept of the present invention, without creatively designing a structure and an embodiment similar to the technical solution, it shall fall within the scope of protection of the present invention.

Claims (10)

Translated fromChinese

1.一种简易鼻咽拭子抗原检测装置，其特征在于：包括：1. A simple nasopharyngeal swab antigen detection device, characterized in that: comprising:样本合成筒(10)，所述样本合成筒(10)配置有筒盖(11)，所述筒盖(11)上开设有进样孔(111)、连接孔(112)；A sample synthesis cylinder (10), the sample synthesis cylinder (10) is equipped with a cylinder cover (11), and the cylinder cover (11) is provided with a sample injection hole (111) and a connecting hole (112);承载体(20)，所述承载体(20)安装在所述连接孔(112)内，可沿连接孔(112)的孔深方向移动，所述承载体(20)上开设有第一容置槽(201)、第二容置槽(202)；A carrier (20), the carrier (20) is installed in the connection hole (112), and can move along the hole depth direction of the connection hole (112), the carrier (20) is provided with a first container Set groove (201), the second accommodating groove (202);抗原检测试纸(30)，所述抗原检测试纸(30)设置在所述第二容置槽(202)内，所述抗原检测试纸(30)靠近所述样本合成筒(10)的一端设置有隔离薄膜(203)，所述隔离薄膜(203)位于第二容置槽(202)的开口处，所述样本合成筒(10)的内部筒底上设置有尖锐凸起(12)，位于隔离薄膜(203)下方；Antigen detection test paper (30), the antigen detection test paper (30) is arranged in the second accommodating tank (202), the end of the antigen detection test paper (30) near the sample synthesis cylinder (10) is provided with An isolation film (203), the isolation film (203) is located at the opening of the second holding tank (202), and a sharp protrusion (12) is arranged on the inner cylinder bottom of the sample synthesis cylinder (10), which is located at the isolation Below the film (203);储液管(31)，所述储液管(31)置于所述样本合成筒(10)内的一端设置有棉球(312)，另一端设置有进液控制结构，所述储液管(31)内盛有裂解液。A liquid storage tube (31), one end of the liquid storage tube (31) placed in the sample synthesis cylinder (10) is provided with a cotton ball (312), and the other end is provided with a liquid inlet control structure, the liquid storage tube (31) filled with lysate.2.根据权利要求1所述的一种简易鼻咽拭子抗原检测装置，其特征在于：所述进样孔(111)配置有橡胶塞。2. A simple nasopharyngeal swab antigen detection device according to claim 1, characterized in that: the sampling hole (111) is equipped with a rubber stopper.3.根据权利要求1或2所述的一种简易鼻咽拭子抗原检测装置，其特征在于：所述简易鼻咽拭子抗原检测装置还包括：采样棉棒，当采样棉棒采样完毕时，通过进样孔(111)延伸进所述样本合成筒(10)内。3. A kind of simple nasopharyngeal swab antigen detection device according to claim 1 or 2, characterized in that: said simple nasopharyngeal swab antigen detection device also comprises: sampling cotton swab, when the sampling cotton swab is finished sampling , extending into the sample synthesis tube (10) through the sample injection hole (111).4.根据权利要求1所述的一种简易鼻咽拭子抗原检测装置，其特征在于：所述承载体(20)的底端为柱状体(204)，所述柱状体(204)上设置有外螺纹，所述连接孔(112)的孔壁上设置有与所述柱状体(204)上的外螺纹相配合的内螺纹。4. A simple nasopharyngeal swab antigen detection device according to claim 1, characterized in that: the bottom end of the carrier (20) is a columnar body (204), and the columnar body (204) is provided with There are external threads, and the hole wall of the connection hole (112) is provided with internal threads that match the external threads on the columnar body (204).5.根据权利要求4所述的一种简易鼻咽拭子抗原检测装置，其特征在于：所述柱状体(204)上还设置有第一限位环(205)、第二限位环(206)，所述第二限位环(206)相较于所述第一限位环(205)更远离所述样本合成筒(10)，所述第一限位环(205)的制作材料为脆性材料。5. A kind of simple and simple nasopharyngeal swab antigen detection device according to claim 4, is characterized in that: the first stop ring (205), the second stop ring ( 206), the second limiting ring (206) is farther away from the sample synthesis cylinder (10) than the first limiting ring (205), and the manufacturing material of the first limiting ring (205) for brittle materials.6.根据权利要求1或5所述的一种简易鼻咽拭子抗原检测装置，其特征在于：所述进液控制结构为密封盖(311)。6. A simple nasopharyngeal swab antigen detection device according to claim 1 or 5, characterized in that: the liquid inlet control structure is a sealing cover (311).7.根据权利要求1所述的一种简易鼻咽拭子抗原检测装置，其特征在于：所述储液管(31)远离所述样本合成筒(10)的一端密封，所述进液控制结构为：设置在所述储液管(31)外壁上的折断刻痕。7. A simple nasopharyngeal swab antigen detection device according to claim 1, characterized in that: the end of the liquid storage tube (31) away from the sample synthesis cylinder (10) is sealed, and the liquid inlet control The structure is: a breaking score arranged on the outer wall of the liquid storage tube (31).8.根据权利要求5所述的一种简易鼻咽拭子抗原检测装置，其特征在于：所述样本合成筒(10)的底壁采用硬性材料制作而成，所述样本合成筒(10)的周向侧壁的中间部位采用软性材料制作而成。8. A simple nasopharyngeal swab antigen detection device according to claim 5, characterized in that: the bottom wall of the sample synthesis cylinder (10) is made of a hard material, and the sample synthesis cylinder (10) The middle part of the circumferential side wall is made of soft material.9.根据权利要求1所述的一种简易鼻咽拭子抗原检测装置，其特征在于：所述样本合成筒(10)采用透明材料制作而成。9. A simple nasopharyngeal swab antigen detection device according to claim 1, characterized in that: the sample synthesis tube (10) is made of transparent material.10.一种采用权利要求8所述简易鼻咽拭子抗原检测装置的检测方法，其特征在于：包括以下步骤：10. A detection method adopting the simple nasopharyngeal swab antigen detection device described in claim 8, is characterized in that: comprises the following steps:S1将进行鼻腔采样后的采样棉棒，从桶盖的进样孔(111)进入样本合成筒(10)内部；利用进液控制结构使裂解液从储液管(31)内流出落入到样本合成筒(10)内；S1 enters the sampling cotton swab after nasal cavity sampling into the sample synthesis cylinder (10) from the sampling hole (111) of the barrel cover; utilizes the liquid inlet control structure to make the lysate flow out from the liquid storage tube (31) and fall into the In the sample synthesis cylinder (10);S2将承载体(20)的柱状体(204)拧进连接孔(112)内，拧至抵触第一限位环(205)的位置，然后挤压样本合成筒(10)的软壁，使储液管(31)的棉球(312)上的裂解液充分落入到样本合成筒(10)内部；S2 Screw the columnar body (204) of the carrier (20) into the connecting hole (112) until it touches the position of the first stop ring (205), and then squeeze the soft wall of the sample synthesis cylinder (10), so that The lysate on the cotton ball (312) of the liquid storage tube (31) fully falls into the inside of the sample synthesis cylinder (10);S3将承载体(20)的柱状体(204)拧至抵触第二限位环(206)的位置，使样本合成筒(10)内部底壁上的尖锐凸起(12)将隔离薄膜(203)破坏，使样本合成筒(10)内部的裂解液充分与抗原检测试纸(30)接触完成检测。S3 Screw the columnar body (204) of the carrier (20) to a position against the second stop ring (206), so that the sharp protrusion (12) on the inner bottom wall of the sample synthesis tube (10) will separate the film (203 ) is destroyed, so that the lysate inside the sample synthesis cylinder (10) is fully in contact with the antigen detection test paper (30) to complete the detection.

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