CN116075330A - Injection devices for administering liquid products - Google Patents
Injection devices for administering liquid productsDownload PDFInfo
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- CN116075330A CN116075330ACN202180062930.8ACN202180062930ACN116075330ACN 116075330 ACN116075330 ACN 116075330ACN 202180062930 ACN202180062930 ACN 202180062930ACN 116075330 ACN116075330 ACN 116075330A
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- housing
- cartridge
- force acting
- injection device
- retaining element
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
- A61M2005/2403—Ampoule inserted into the ampoule holder
- A61M2005/2407—Ampoule inserted into the ampoule holder from the rear
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
- A61M2005/2433—Ampoule fixed to ampoule holder
- A61M2005/2437—Ampoule fixed to ampoule holder by clamping means
- A61M2005/244—Ampoule fixed to ampoule holder by clamping means by flexible clip
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
- A61M2005/2477—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic comprising means to reduce play of ampoule within ampoule holder, e.g. springs
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- Health & Medical Sciences (AREA)
- Vascular Medicine (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Abstract
Translated fromChinese
Description
Translated fromChinese技术领域technical field
本发明涉及一种用于施用液体产品、尤其药物(如例如用于骨质疏松症治疗的特立帕肽)的注射装置。The present invention relates to an injection device for administering a liquid product, especially a medicament such as eg teriparatide for the treatment of osteoporosis.
背景技术Background technique
“药物”的概念此处包括任何可流动的医疗制剂，其适合于穿过器件(如小管或注射针)的受控制的施用，例如包括液体、溶液、凝胶或包含一种或多种医疗有效成分的细悬浮液。药物可以是带有唯一的有效成分的化合物或是带有来自各个容器的多种有效成分的经预混合或共同配制的化合物。药物包括药剂如肽(例如胰岛素、包含胰岛素的药物、包含GLP-1以及衍生或类似的制剂)、蛋白质和激素、生物衍生的或活性的有效成分、基于激素或基因的有效成分、营养制剂、酶和另外的不仅固体(悬浮)或液体形式的物质而且多糖、疫苗、DNS或RNS或卵核苷酸、抗体或抗体的一部分以及合适的基础物质、辅助物质和载体物质。The concept "drug" here includes any flowable medical preparation suitable for controlled administration through a device (such as a small tube or injection needle), including, for example, a liquid, a solution, a gel, or containing one or more medical Fine suspension of active ingredients. Drugs can be compounds with a single active ingredient or premixed or co-formulated compounds with multiple active ingredients from separate containers. Drugs include pharmaceutical agents such as peptides (e.g. insulin, insulin containing drugs, GLP-1 containing and derivatives or similar preparations), proteins and hormones, biologically derived or active active ingredients, hormone or gene based active ingredients, nutritional preparations, Enzymes and further substances not only in solid (suspension) or liquid form but also polysaccharides, vaccines, DNS or RNS or egg nucleotides, antibodies or parts of antibodies and suitable base substances, auxiliary substances and carrier substances.
由WO2016/134491A1已知一种带有用于容纳卡式瓶(Karpule，有时也称为卡普尔瓶)的卡式瓶支架的注射装置，其中，设置有用于将卡式瓶固定在卡式瓶支架处或中的弹性构造的保持元件。Known from WO2016/134491A1 is an injection device with a cartridge holder for accommodating a cartridge (Karpule, sometimes called a Karpule bottle), wherein a device for fixing the cartridge to the cartridge holder is provided. Retaining elements of elastic construction at or in.
发明内容Contents of the invention
本发明的任务是提供一种备选的用于施用液体产品的注射装置，其中，卡式瓶可被固定、尤其可被无间隙地保持在卡式瓶支架处或中，以便于有助于注射装置的配量精度。The object of the present invention is to provide an alternative injection device for administering liquid products, in which the cartridge can be fixed, in particular held without play, at or in the cartridge holder in order to facilitate The dosing accuracy of the injection device.
此外，本发明的任务是提供一种将卡式瓶装配在卡式瓶支架处或中的方法，其中，尤其卡式瓶被无间隙地保持在卡式瓶支架处或中。Furthermore, it is an object of the present invention to provide a method for mounting a cartridge on or in a cartridge holder, wherein in particular the cartridge is held without play on or in the cartridge holder.
这些任务通过独立权利要求的对象来解决。有利的实施形式由从属权利要求得出。These tasks are solved by the objects of the independent claims. Advantageous embodiments emerge from the subclaims.
下面，远端意味着朝向注射装置的注射针侧的端部的方向，且近端朝向驱动和/或配量设备侧的且/或外壳侧的端部。In the following, distal means the direction towards the needle-side end of the injection device, and proximal towards the drive and/or metering device-side and/or housing-side end.
本发明涉及一种用于施用液体产品的注射装置。此外，注射装置包括用于容纳卡式瓶且用于固定在注射装置的外壳处或中的卡式瓶支架。此外，注射装置包括弹性构造的用于将卡式瓶固定在卡式瓶支架处或中的保持元件，其中，保持元件在近端方向上被定位在外壳处或中且在远端方向上被支撑在卡式瓶处或中，尤其经由相应的力配合的和/或形状配合的连接被定位且被支撑且如此地构造，即，保持元件将在远端方向上作用的力施加到卡式瓶上。保持元件此外如此地构造，即，保持元件将在轴向方向上起作用的摩擦力施加到注射装置的外壳上以用于将卡式瓶固定在卡式瓶支架处或中且在轴向方向上起作用的摩擦力相对在远端方向上起作用的力起作用。The present invention relates to an injection device for administering a liquid product. Furthermore, the injection device comprises a cartridge holder for receiving the cartridge and for fixing at or in the housing of the injection device. Furthermore, the injection device comprises an elastically configured retaining element for securing the cartridge at or in a cartridge holder, wherein the retaining element is positioned on or in the housing in the proximal direction and is held in the distal direction. Supported at or in the cartridge, in particular via a corresponding non-positive and/or form-fit connection, is positioned and supported and is configured in such a way that the retaining element exerts a force acting in the distal direction on the cartridge on the bottle. The holding element is also designed in such a way that the holding element exerts a frictional force acting in the axial direction on the housing of the injection device for securing the cartridge on or in the cartridge holder and in the axial direction The frictional force acting upward acts against the force acting in the distal direction.
保持元件具有保持功能和/或紧固功能和/或定位功能。保持元件具有弹簧力。保持元件可以如下方式用于注射装置的一个部件在另一部件处或中的保持和/或紧固和/或定位，即，在压缩状态中的保持元件将部件中的一个保持在相对于另一个部件的确定的位置中。因此，保持元件可将注射装置的部件保持在注射装置中的限定的位置中。该限定的位置通过待保持的部件相对于注射装置的另一个部件的局部布置确定。注射装置的部件可以是卡式瓶支架中的卡式瓶。卡式瓶可以以如下方式优选借助于保持元件无间隙地保持在卡式瓶支架处或中，即，在卡式瓶支架中的卡式瓶在远端测在轴向止挡接触中且在近端侧借助于保持元件被保持。保持元件的弹簧力是在远端方向上作用的力，其作用在卡式瓶上以使卡式瓶优选无间隙地保持在卡式瓶支架处或中。通过这种方式，可以补偿制造和装配公差。此外，当放置注射针时，通过保持元件的弹簧力可防止卡式瓶相对于外壳或卡式瓶支架移动。The holding element has a holding function and/or a fastening function and/or a positioning function. The holding element has a spring force. The retaining element can be used for retaining and/or fastening and/or positioning of one part of the injection device at or in the other part in such a way that the retaining element in the compressed state holds one of the parts in relation to the other. In a defined location of a component. Thus, the holding element can hold a component of the injection device in a defined position in the injection device. This defined position is determined by the local arrangement of the component to be held relative to another component of the injection device. The part of the injection device may be a cartridge in a cartridge holder. The cartridge can be held at or in the cartridge holder, preferably by means of the retaining element, without play, in such a way that the cartridge in the cartridge holder is in contact with the axial stop at the distal end and at the The proximal side is held by means of a holding element. The spring force of the holding element is a force acting in the distal direction which acts on the cartridge in order to hold the cartridge preferably without play on or in the cartridge holder. In this way, manufacturing and assembly tolerances can be compensated. Furthermore, the cartridge is prevented from moving relative to the housing or the cartridge holder by the spring force of the retaining element when the injection needle is placed.
优选地，在轴向方向上起作用的摩擦力可至少部分、优选完全地补偿在远端方向上起作用的力。在轴向方向上起作用的摩擦力相对在远端方向上起作用的力起作用。在轴向方向上起作用的摩擦力可优选如此地相对在远端方向上起作用的力起作用，即，产生的力约为零。Preferably, the friction force acting in the axial direction can at least partially, preferably completely compensate the force acting in the distal direction. The frictional force acting in the axial direction acts against the force acting in the distal direction. The frictional force acting in the axial direction can preferably act relative to the force acting in the distal direction in such a way that the resulting force is approximately zero.
因此可实现如下，即，保持元件的持久的弹簧力不作用到卡式瓶上。由此防止如下，即，弹簧力由保持元件经由另一部件作用到注射装置上且因此将非期望的力施加到注射装置的部件上。因此，例如在注射装置中的卡扣连接、例如在注射装置的外壳与卡式瓶支架之间的卡扣连接的松弛可被最小化。此外如下是有利的，即，在卡式瓶相对卡式瓶支架在近端方向上的相对轴向位移的情形中，不仅保持元件的在远端方向上起作用的力而且保持元件的在轴向方向上起作用的摩擦力必须被克服。因此，注射装置的配量精度可被改善。It is thus possible to achieve that the permanent spring force of the retaining element does not act on the cartridge. This prevents the spring force from acting on the injection device from the retaining element via another component and thus exerting undesired forces on components of the injection device. Thus, slack in eg a snap connection in the injection device, eg between the housing of the injection device and the cartridge holder, can be minimized. Furthermore, it is advantageous that in the case of a relative axial displacement of the cartridge relative to the cartridge holder in the proximal direction, not only the forces acting in the distal direction of the retaining element but also the axial force of the retaining element The friction force acting in the direction has to be overcome. Thus, the dosing accuracy of the injection device can be improved.
保持元件是注射装置的单独的部件。保持元件具有保持功能和/或紧固功能和/或定位功能。保持元件可优选由塑料构成。塑料包括可生物降解的和/或不可生物降解的塑料。保持元件弹性地构造。备选地，保持元件可具有一个或多个弹性构造的部件。保持元件可呈环形地或呈套筒状地构造。保持元件可设置在注射装置的外壳的内部中。保持元件可作为单独的部件被置入或插入到外壳中。The holding element is a separate part of the injection device. The holding element has a holding function and/or a fastening function and/or a positioning function. The holding element can preferably consist of plastic. Plastics include biodegradable and/or non-biodegradable plastics. The holding element is configured elastically. Alternatively, the retaining element can have one or more elastically configured parts. The retaining element can be annular or sleeve-shaped. The holding element can be arranged in the interior of the housing of the injection device. The holding element can be inserted or inserted into the housing as a separate part.
保持元件可包括弹簧元件或构造成弹簧元件，其中，弹簧元件施加在远端方向上起作用的力。The holding element can comprise a spring element or be designed as a spring element, wherein the spring element exerts a force acting in the distal direction.
弹簧元件可呈环形地或呈套筒状地构造。此外，弹簧元件可优选呈圆柱形地构造。The spring element can be annular or sleeve-shaped. Furthermore, the spring element can preferably be configured cylindrically.
在弹簧元件处可设置有第一和第二弹簧座。弹簧元件可包括多个卡箍(Bügel)和多个连接接片，其中，第一弹簧座可经由多个卡箍且经由多个连接接片与第二弹簧座相连接。卡箍和优选连接接片在轴向方向上可弹性变形。备选地，连接接片可轴向刚性地构造。卡箍在周缘方向上延伸，其中，其相对远端或相对近端弯曲地构造。第一弹簧座可经由第一连接接片与第一卡箍相连接，其中，第一卡箍可经由第二连接接片与第二卡箍且第二卡箍可经由第二连接接片在第二弹簧座处被连接。第一和第二卡箍可构成弹性的弯曲臂。因此，第一和第二卡箍经由连接接片在轴向方向上由第一和第二弹簧座伸出。A first and a second spring seat can be arranged on the spring element. The spring element can comprise a plurality of clips and a plurality of connecting webs, wherein the first spring seat can be connected to the second spring seat via a plurality of clips and via a plurality of connecting webs. The clip and preferably the connecting web are elastically deformable in the axial direction. Alternatively, the connecting web can be embodied axially rigid. The clip extends in the peripheral direction, wherein it is curved relative to the distal end or relative to the proximal end. The first spring seat can be connected to the first clamp via the first connecting lug, wherein the first clamp can be connected to the second clamp via the second connecting lug and the second clamp can be connected to the second clamp via the second connecting lug. The second spring seat is connected. The first and second clips may constitute resilient flexure arms. Thus, the first and the second clip protrude in the axial direction from the first and the second spring seat via the connecting web.
备选地，在弹簧元件处同样可设置有其它数量的卡箍、连接接片和弹簧座。Alternatively, another number of clips, connecting webs and spring seats can likewise be provided on the spring element.
备选地，弹簧元件可尤其不具有卡箍和连接接片。弹簧元件可呈套筒状地构造且具有第一和第二弹簧座。呈套筒状的弹簧元件弹性地构造。Alternatively, the spring element can in particular not have clips and connecting webs. The spring element can be designed like a sleeve and have a first and a second spring seat. The sleeve-shaped spring element is configured elastically.
此外，弹簧元件同样可具有不同的设计方案，前提是该弹簧元件可沿轴向轴线被负荷压力。Furthermore, the spring element can likewise be of different configurations, provided that it can be stressed along the axial axis.
保持元件可包括夹紧元件或构造成夹紧元件，其中，夹紧元件施加在轴向方向上起作用的摩擦力。夹紧元件可弹性地构造。The holding element can comprise a clamping element or be designed as a clamping element, wherein the clamping element exerts a frictional force acting in the axial direction. The clamping element can be configured elastically.
保持元件优选如此地构造，即，保持元件将在远端方向上起作用的力施加到卡式瓶上以用于将卡式瓶无间隙地保持在卡式瓶支架处或中。特别优选地，保持元件的弹簧元件或构造成弹簧元件的保持元件如此地构造，即，弹簧元件或构造成弹簧元件的保持元件将在远端方向上起作用的力施加到卡式瓶上以用于将卡式瓶无间隙地保持在卡式瓶支架处或中。The holding element is preferably designed in such a way that it exerts a force acting in the distal direction on the cartridge for holding the cartridge without play on or in the cartridge holder. Particularly preferably, the spring element of the retaining element or the retaining element configured as a spring element is designed in such a way that the spring element or the retaining element configured as a spring element exerts a force acting in the distal direction on the cartridge to For holding the cartridge without play at or in the cartridge holder.
此外，保持元件优选如此地构造，即，保持元件将在轴向方向上起作用的摩擦力施加到外壳上以用于构成在保持元件与外壳之间的摩擦配合的连接。特别优选地，保持元件的夹紧元件或构造成夹紧元件的保持元件如此地构造，即，夹紧元件或构造成夹紧元件的保持元件将在轴向方向上起作用的摩擦力施加到外壳上以用于构成在保持元件与外壳之间的摩擦配合的连接。Furthermore, the holding element is preferably designed in such a way that it exerts a frictional force acting in the axial direction on the housing in order to form a friction-fit connection between the holding element and the housing. Particularly preferably, the clamping element of the retaining element or the retaining element configured as a clamping element is designed in such a way that the clamping element or the retaining element configured as a clamping element exerts a frictional force acting in the axial direction on the on the housing for forming a friction-fit connection between the retaining element and the housing.
卡式瓶支架可包括卡式瓶支架外壳、尤其呈圆柱形的卡式瓶支架外壳。卡式瓶支架、尤其卡式瓶支架外壳如此地构造，即，其可容纳卡式瓶。在卡式瓶支架的远端端部处可设置有针连接元件，其设置用于注射针的可解开的固定。卡式瓶支架可经由形状配合和/或摩擦配合被固定在外壳处或中。The cartridge holder may comprise a cartridge holder housing, in particular a cylindrical cartridge holder housing. The cartridge holder, in particular the cartridge holder housing, is designed in such a way that it can accommodate a cartridge. At the distal end of the cartridge holder there may be provided a needle connection element provided for releasable fixation of the injection needle. The cartridge holder may be secured at or in the housing via a form fit and/or friction fit.
卡式瓶支架的近端端部可如此地构造，即，卡式瓶支架可经由形状配合和/或摩擦配合被固定在注射装置的外壳处或中。特别优选地，在卡式瓶支架与外壳之间可设置有卡扣连接。备选地，该连接可构造成粘合连接或焊接连接。在卡式瓶支架与外壳之间的连接可以是在卡式瓶支架与外壳之间的轴向固定的、尤其轴向固定且抗扭的连接。备选地，在卡式瓶支架与外壳之间的连接可以可解开地构造。The proximal end of the cartridge holder can be designed in such a way that the cartridge holder can be fixed on or in the housing of the injection device via a form fit and/or a friction fit. Particularly preferably, a snap connection can be provided between the cartridge holder and the housing. Alternatively, the connection can be designed as an adhesive or welded connection. The connection between the cartridge holder and the housing can be an axially fixed, in particular axially fixed and rotationally fixed connection between the cartridge holder and the housing. Alternatively, the connection between the cartridge holder and the housing can be designed to be releasable.
特别优选地，卡式瓶支架至少部分由外壳容纳。因此，在容纳或定位在外壳中的保持元件在插入以卡式瓶容纳的卡式瓶支架的情形中或之后尤其通过在卡式瓶的近端端部、尤其近端的卡式瓶边缘与保持元件之间的止挡接触将在远端方向上起作用的力施加到卡式瓶上，以便于尤其将卡式瓶无间隙地保持在卡式瓶支架处或中。保持元件在远端方向上被支撑在卡式瓶处、尤其在卡式瓶的近端端部处、特别优选地在近端的卡式瓶边缘处。特别优选地，保持元件可包括支撑元件，其中，保持元件的支撑元件被支撑在卡式瓶的近端端部处、尤其在近端的卡式瓶边缘处。此外，保持元件可优选地包括近端定位元件，以将保持元件在近端方向上定位在外壳处或中。保持元件的弹簧元件可以对于在外壳中的定位预紧、卸载或预压缩。支撑元件和/或近端定位元件和/或更下面描述的远端定位元件可以弹性构造。Particularly preferably, the cartridge holder is at least partially accommodated by the housing. Thus, the holding element accommodated or positioned in the housing is in particular connected to the proximal end of the cartridge, in particular the proximal edge of the cartridge, during or after insertion into a cartridge holder held in a cartridge. The stop contact between the retaining elements exerts a force acting in the distal direction on the cartridge in order to hold the cartridge on or in the cartridge holder, in particular without play. The holding element is supported in the distal direction on the cartridge, in particular at the proximal end of the cartridge, particularly preferably at the proximal edge of the cartridge. Particularly preferably, the holding element can comprise a support element, wherein the support element of the holding element is supported at the proximal end of the cartridge, in particular at the proximal edge of the cartridge. Furthermore, the retaining element may preferably comprise a proximal positioning element for positioning the retaining element at or in the housing in the proximal direction. The spring element of the retaining element can be pretensioned, unloaded or precompressed for positioning in the housing. The support element and/or the proximal positioning element and/or the distal positioning element described further below can be elastically configured.
注射装置的外壳可包括用于施用液体产品、尤其在卡式瓶中被容纳的药物的驱动和/或配量设备。为此，驱动和/或配量设备可以沿远端方向移动在卡式瓶中容纳的塞子以倒出液体产品、尤其药物。The housing of the injection device may comprise a drive and/or dosing device for administering a liquid product, in particular a medicament contained in a cartridge. To this end, the drive and/or dosing device can move the bung accommodated in the cartridge in the distal direction to pour out the liquid product, in particular the medicament.
驱动和/或配量设备可如此地构造，即，液体产品的经确定的剂量或液体产品的待设定的剂量可被调整且被倒出。The drive and/or dosing device can be designed in such a way that a determined dose of the liquid product or a dose to be set of the liquid product can be adjusted and dispensed.
此外，本发明涉及一种用于将卡式瓶装配在卡式瓶支架处或中的方法。Furthermore, the invention relates to a method for fitting a cartridge at or in a cartridge holder.
在一个步骤中提供了注射装置的外壳。外壳可包括如上面所描述的用于施用液体产品、尤其被容纳在卡式瓶中的药物的驱动和/或配量设备。The housing of the injection device is provided in one step. The housing may comprise an actuation and/or dosing device as described above for administering a liquid product, in particular a medicament contained in a cartridge.
此外，如上面所描述的弹性构造的保持元件在近端方向上被置入或插入到注射装置的外壳中以用于将卡式瓶固定到卡式瓶支架处或中。卡式瓶支架用于容纳卡式瓶。保持元件被置入或插入到注射装置的外壳中，尤其直至保持元件在近端和远端方向上被定位在外壳处或中，尤其经由力配合的和/或形状配合的连接被定位在外壳处或中。保持元件优选在远端方向上和在近端方向上被定位在外壳处或中，尤其经由力配合的和/或形状配合的连接被定位在外壳处或中。该连接可构造成摩擦连接和/或止挡连接。为此，保持元件可具有远端的和近端的定位元件。远端的和近端的定位元件可优选经由摩擦连接和/或止挡连接与外壳相连接，尤其可解开地相连接。远端的和/或近端的定位元件可优选设置在保持元件的内侧表面处或在外侧表面处。备选地，远端的和/或近端的定位元件可设置在保持元件的远端的和/或近端的端部处。外壳可具有相应的配对定位元件。特别优选地，外壳可具有用于定位保持元件的止挡面或摩擦面。特别优选地，外壳的止挡面与保持元件的远端的定位元件且外壳的止挡面和/或摩擦面与近端的定位元件共同起作用，以便于将保持元件定位且防丢失地保持在外壳处或中。与保持元件使用的外壳可例如作为组合件单元是可运输的。该组合件单元可被安装在其它位置处、例如在带有容纳卡式瓶的卡式瓶支架的装配位置处。Furthermore, a resiliently configured retaining element as described above is inserted or inserted in the proximal direction into the housing of the injection device for securing the cartridge at or in the cartridge holder. Cartridge holders are used to accommodate cartridges. The holding element is placed or inserted into the housing of the injection device, in particular until the holding element is positioned at or in the housing in the proximal and distal directions, in particular via a force-fit and/or form-fit connection. at or in. The holding element is preferably positioned on or in the housing in the distal direction and in the proximal direction, in particular via a non-positive and/or form-fit connection. The connection can be designed as a frictional connection and/or a stop connection. For this purpose, the holding element can have distal and proximal positioning elements. The distal and proximal positioning elements can preferably be connected to the housing via a friction connection and/or a stop connection, in particular connected in a detachable manner. The distal and/or proximal positioning elements can preferably be arranged on the inner surface or on the outer surface of the holding element. Alternatively, the distal and/or proximal positioning element can be arranged at the distal and/or proximal end of the holding element. The housing may have corresponding mating positioning elements. Particularly preferably, the housing can have a stop or friction surface for positioning the holding element. Particularly preferably, the stop surface of the housing cooperates with the distal positioning element of the holding element and the stop surface and/or friction surface of the housing cooperates with the proximal positioning element in order to position and hold the holding element in a secure manner. at or in the shell. The housing used with the holding element can be transportable, for example, as an assembly unit. The assembly unit may be mounted at other locations, for example at an assembly location with a cartridge holder accommodating a cartridge.
在另一步骤中，以其包括卡式瓶的卡式瓶支架在近端方向上被置入或被插入到注射装置的外壳中，直至卡式瓶支架相对于外壳经由形状配合和/或摩擦配合被固定在外壳处，其中，卡式瓶的近端端部、尤其近端的卡式瓶边缘与保持元件达到止挡接触，且保持元件将在远端方向上起作用的力施加到卡式瓶上。保持元件为此可具有支撑元件。保持元件在远端方向上被支撑在卡式瓶处或中，尤其经由支撑元件被支撑。支撑元件如此地构造，即，卡式瓶的近端端部、尤其近端的卡式瓶边缘可与支撑元件达到止挡接触，以便于尤其在轴向方向上预紧保持元件。保持元件的支撑元件优选布置在保持元件的内侧表面处。在插入卡式瓶支架的情形中，在保持元件的远端的定位元件与外壳之间的力配合的和/或形状配合的连接优选被解开。此外，保持元件、尤其保持元件的夹紧元件将在轴向方向上起作用的摩擦力施加到外壳上以用于将卡式瓶固定在卡式瓶支架处或中，其中，在轴向方向上起作用的摩擦力相对在远端方向上起作用的力起作用。此外，保持元件在近端方向上被定位在外壳处或中、尤其经由近端的定位元件被定位在外壳处或中且在远端方向上被支撑在卡式瓶的近端端部处、尤其在近端的卡式瓶边缘处。In a further step, the cartridge holder with which the cartridge is included is placed or inserted into the housing of the injection device in the proximal direction until the cartridge holder is relative to the housing via a form fit and/or friction The fit is fixed at the housing, wherein the proximal end of the cartridge, in particular the proximal edge of the cartridge, comes into stop contact with the retaining element, and the retaining element applies a force acting in the distal direction to the cartridge. on the bottle. The holding element can have a support element for this purpose. The holding element is supported at or in the cartridge in the distal direction, in particular via the supporting element. The supporting element is designed in such a way that the proximal end of the cartridge, in particular the proximal edge of the cartridge, can come into stop contact with the supporting element in order to prestress the holding element, in particular in the axial direction. The support element of the holding element is preferably arranged at the inner side surface of the holding element. When inserting the cartridge holder, the non-positive and/or form-fit connection between the positioning element at the distal end of the holding element and the housing is preferably released. Furthermore, the holding element, in particular the clamping element of the holding element, exerts a frictional force acting in the axial direction on the housing for fixing the cartridge on or in the cartridge holder, wherein in the axial direction The frictional force acting upward acts against the force acting in the distal direction. Furthermore, the retaining element is positioned at or in the housing in the proximal direction, in particular positioned at or in the housing via the proximal positioning element and is supported in the distal direction at the proximal end of the cartridge, Especially at the proximal edge of the cartridge.
特别优选地，保持元件可借助于工具、尤其借助于挤压柱在近端方向上被置入或插入到外壳中，其中，工具、尤其挤压柱轴向在近端方向上移动设置在外壳中的保持元件，直至保持元件在近端和远端方向上尤其经由力配合的和/或形状配合的连接定位在外壳处或中。工具、尤其挤压柱和/或保持元件为此可优选包括挺杆元件和/或配对挺杆元件。备选地或额外地，保持元件的支撑元件可构成保持元件的配对挺杆元件。在保持元件与外壳之间的力配合的和/或形状配合的连接优选可解开地构造。保持元件优选在远端方向上和在近端方向上被定位在外壳处或中。保持元件可在远端方向上和在近端方向上与外壳达到力配合的和/或形状配合的连接。特别优选地，该连接可构造成摩擦连接和/或止挡连接。特别优选地，保持元件可在近端方向上经由摩擦连接且在远端方向上经由止挡连接和/或摩擦连接被定位在外壳处或中。Particularly preferably, the retaining element can be placed or inserted into the housing in the proximal direction by means of a tool, in particular a pressing pin, wherein the tool, in particular the pressing pin, is arranged axially displaceable in the proximal direction on the housing until the holding element is positioned at or in the housing in the proximal and distal direction, in particular via a non-positive and/or form-fit connection. The tool, in particular the press pin and/or the holding element, can preferably comprise a tappet element and/or a counter tappet element for this purpose. Alternatively or additionally, the support element of the holding element can form the counterpart tappet element of the holding element. The non-positive and/or form-fit connection between the retaining element and the housing is preferably designed to be releasable. The holding element is preferably positioned on or in the housing in the distal direction and in the proximal direction. The retaining element can be connected to the housing in a non-positive and/or form-fit manner in the distal direction and in the proximal direction. Particularly preferably, the connection can be designed as a friction connection and/or a stop connection. Particularly preferably, the holding element can be positioned on or in the housing via a friction connection in the proximal direction and via a stop connection and/or a friction connection in the distal direction.
在将保持元件置入或插入到外壳中之后，保持元件通过摩擦配合和/或形状配合在远端和/或近端方向上轴向固定地相对于外壳被保持。After the holding element has been inserted or inserted into the housing, the holding element is held axially fixed relative to the housing in the distal and/or proximal direction by means of a friction fit and/or a form fit.
特别优选地，在轴向方向上起作用的摩擦力至少部分、优选完全补偿在远端方向上起作用的力。在轴向方向上起作用的摩擦力可优选如此地相对在远端方向上起作用的力起作用，即，产生的力约为零。特别优选地，在轴向方向上起作用的摩擦力大于在远端方向上起作用的力。Particularly preferably, the friction force acting in the axial direction at least partially, preferably completely compensates the force acting in the distal direction. The frictional force acting in the axial direction can preferably act relative to the force acting in the distal direction in such a way that the resulting force is approximately zero. Particularly preferably, the friction force acting in the axial direction is greater than the force acting in the distal direction.
保持元件可包括弹簧元件或构造成弹簧元件，其中，弹簧元件施加在远端方向上起作用的力。The holding element can comprise a spring element or be designed as a spring element, wherein the spring element exerts a force acting in the distal direction.
保持元件可以是夹紧元件或构造成夹紧元件，其中，夹紧元件施加在轴向方向上起作用的摩擦力。The holding element can be a clamping element or be designed as a clamping element, wherein the clamping element exerts a frictional force acting in the axial direction.
附图说明Description of drawings
本发明在下面在多个附图处进行描述。其中：The invention is described below in several figures. in:
图1：显示了用于施用液体产品的注射装置的一种根据本发明的实施形式的分解视图。Figure 1 : shows an exploded view of an embodiment according to the invention of an injection device for administering a liquid product.
图2a：显示了根据图1的注射装置的一部分的纵截面视图，其中，保持元件(9)借助于工具(13)在近端方向上被插入到注射装置的外壳(6)中。Figure 2a: shows a longitudinal sectional view of a part of the injection device according to Figure 1, wherein the retaining element (9) is inserted in the proximal direction into the housing (6) of the injection device by means of the tool (13).
图2b：显示了根据图1的注射装置的一部分的纵截面视图，其中，保持元件(9)借助于工具(13)被插入在注射装置的外壳(6)中且经由摩擦配合和/或形状配合至少在近端方向上被定位在外壳(6)处或中。Fig. 2b: shows a longitudinal section view of a part of the injection device according to Fig. 1, wherein the retaining element (9) is inserted in the housing (6) of the injection device by means of the tool (13) and via a friction fit and/or form The fit is positioned at or in the housing (6), at least in the proximal direction.
图3：显示了根据图1的注射装置的一部分的纵截面视图，其中，保持元件(9)借助于工具(13)被插入在注射装置的外壳(6)中且经由摩擦配合和/或形状配合在远端和近端方向上被定位在外壳(6)处或中。Figure 3: shows a longitudinal section view of a part of the injection device according to Figure 1, wherein the retaining element (9) is inserted in the housing (6) of the injection device by means of the tool (13) and via a friction fit and/or form The fit is positioned at or in the housing (6) in distal and proximal direction.
图4a：显示了根据图1的注射装置的一部分的纵截面视图，其中，以卡式瓶(10)容纳的卡式瓶支架(8)在近端方向上被置入或插入到注射装置的外壳(6)中，其中，保持元件(9)在远端和近端方向上被定位在外壳(6)处或中。Figure 4a: shows a longitudinal sectional view of a part of the injection device according to Figure 1, wherein the cartridge holder (8) accommodated in the cartridge (10) is placed or inserted into the injection device in the proximal direction In the housing (6), wherein the retaining element (9) is positioned at or in the housing (6) in distal and proximal direction.
图4b：显示了根据图1的注射装置的一部分的纵截面视图，其中，卡式瓶(10)的近端端部、尤其近端的卡式瓶边缘(10a)与被定位在外壳(6)处或中的保持元件(9)达到止挡接触。Figure 4b: shows a longitudinal sectional view of a part of the injection device according to Figure 1, wherein the proximal end of the cartridge (10), in particular the proximal cartridge edge (10a), is positioned in the housing (6 ) at or in the retaining element (9) reaches the stop contact.
图4c：显示了根据图1的注射装置的一部分的纵截面视图，其中，卡式瓶支架(8)经由卡扣连接与外壳(6)相连接且保持元件(9)将在远端方向上起作用的力施加到卡式瓶(10)上以用于将卡式瓶(10)无间隙地保持在卡式瓶支架(8)处或中，且保持元件(9)将在轴向方向上起作用的摩擦力施加到外壳(6)上以用于将卡式瓶(10)固定在卡式瓶支架(8)处或中。Figure 4c: shows a longitudinal section view of a part of the injection device according to Figure 1, wherein the cartridge holder (8) is connected to the housing (6) via a snap connection and the retaining element (9) will be in the distal direction An active force is applied to the cartridge (10) for holding the cartridge (10) at or in the cartridge holder (8) without play, and the holding element (9) will be in the axial direction A frictional force acting on the housing (6) is used to secure the cartridge (10) at or in the cartridge holder (8).
具体实施方式Detailed ways
在图1中示出了用于施用液体产品的注射装置的一种根据本发明的实施形式的分解视图。注射装置包括卡式瓶支架(8)，其可容纳卡式瓶(10)，其中，卡式瓶支架(8)可与外壳(6)轴向固定地、尤其轴向和径向固定地相连接。该连接可构造成卡扣连接。为此，卡式瓶支架(8)可具有卡式瓶支架突起(8a)，其可被卡入到设置在外壳(6)处的外壳凹口(6a)中。外壳(6)可优选包括外壳导向槽(6b)，其可与布置在卡式瓶支架(8)处的卡式瓶支架导向接片(8b)在接合中，以便于将以卡式瓶(10)容纳的卡式瓶支架(8)在近端方向上插入到外壳(6)中。在卡式瓶支架(8)的远端端部处设置有针连接元件(8c)，其设置用于注射针(不可见)的可解开的固定。此外，注射装置包括封盖(12)，其可经由可解开的连接与卡式瓶支架(8)相连接。为此，卡式瓶支架(8)具有卡式瓶支架凸轮(8d)，其可锁入到封盖(12)的环形槽(不可见)中。优选地，封盖(12)的环形槽(不可见)可具有凹处(不可见)，从而封盖(12)相对于卡式瓶支架(8)可抗扭地布置。此外设置有弹性构造的保持元件(9)。保持元件(9)呈环形或呈套筒状地构造。保持元件(9)包括弹簧元件(9a)。保持元件(9)同样可构造成弹簧元件(9a)。此外，保持元件(9)包括夹紧元件(9b)。保持元件(9)同样可构造成夹紧元件(9b)。保持元件(9)包括远端的定位元件(9c)和近端的定位元件(9d)。此外，保持元件(9)包括支撑元件(9e)。支撑元件(9e)用于支撑卡式瓶(10)、尤其卡式瓶(10)的近端的卡式瓶边缘(10a)。此外，注射装置包括导向套筒(1)。导向套筒(1)与外壳(6)经由设置在导向套筒(1)处的导向套筒接片(1c)和被安装在外壳(6)处的槽(不可见)抗扭地且经由导向套筒(1)的向内伸出的导向套筒突起(1d)和被安装在外壳(6)处的外壳保持臂(6c；例如在图4a中)轴向固定地相连接。备选地，导向套筒(1)和外壳(6)可一件式地构造。导向套筒(1)具有接合元件(1a)，其可与螺纹杆(3)的齿部共同起作用。此外，注射装置包括旋转套筒(2)，其轴向固定地且可转动地与导向套筒(1)相连接。为此，旋转套筒(2)具有旋转套筒环形接片(2c)，其在其近端的侧面处可轴向止挡到导向套筒保持臂(1b)处、优选到两个导向套筒保持臂(1b)处，其中，此外旋转套筒棱边(2d)可构成与导向套筒(1)的导向套筒端侧(不可见)的轴向的止挡接触。旋转套筒(2)同样包括接合元件(2a)，其可与螺纹杆(3)的齿部共同起作用。螺纹杆(3)的齿部包括齿(3a)、优选多个齿、特别优选四个齿。此外，螺纹杆(3)具有外螺纹(3b)，其与外壳(6)的内螺纹(6i，例如在图4a中)构成螺纹连接。备选地，内螺纹可设置在导向套筒(1)处。旋转套筒(2)和导向套筒(1)的接合元件(2a,1a)到螺纹杆(3)的齿部中的接合机构构造成棘轮机构。旋转套筒(2)和导向套筒(1)的接合元件(2a,1a)与螺纹杆(3)的齿部如此地共同起作用，即，在经确定的剂量的配定(Aufdosieren)的情形中且在经确定的剂量的倒出的情形中产生咔嗒噪音。为了当最后的剂量被倒出时防止进一步剂量的调整，旋转套筒(2)具有旋转套筒止挡(不可见)，其可与设置在螺纹杆(3)处的螺纹杆止挡(3c)产生止挡接触。此外，注射装置包括配量套筒(4)。配量套筒(4)经由配量套筒接片(4a)与外壳槽(不可见)相对于注射装置的外壳(6)抗扭地且轴向可移动地被支承。用户可借助于布置在配量套筒(4)的近端端部处的配量按钮(4c)轴向在近端方向上移动配量套筒(4)，且借助于布置在近端端部处的倒出按钮(5)轴向在远端方向上移动。倒出按钮(5)轴向固定地、尤其轴向固定且抗扭地经由倒出按钮突起(Ausschüttknopfvorspruch)(5a)与配量按钮(4c)相连接。为了显示各个配量运动，配量套筒(4)优选具有显示器(4d)。配量套筒(4)的显示器(4d)可通过设置在外壳(6)处的外壳窗口(6d)可见，其中，注射装置处在哪个位置对于用户而言是可见的。配量套筒(4)经由螺纹连接与旋转套筒(2)相连接。配量套筒(4)的内侧包括配量套筒螺纹(4b)，其与在旋转套筒(2)的外侧处的旋转套筒螺纹(2b)在接合中。此外，注射装置包括锁定环(11)，其在其远端端部处具有棘轮齿(11a)，其经由锁定环(11)的锁销臂(11b)与导向套筒(1)相连接。锁定环(11)的棘轮齿(11a)可接合到导向套筒(1)的棘轮齿部(不可见)中，其中，锁定环(11)的棘轮齿(11a)和导向套筒(1)的棘轮齿部(不可见)如此地构造，即，棘轮齿(11a)相对于导向套筒(1)的棘轮齿(不可见)在第一转动方向上可滑动经过导向套筒(1)的棘轮齿(不可见)，且在相反于第一转动方向的转动方向上、即在第二转动方向上可防止在锁定环(11)和导向套筒(1)之间的相对转动。锁定环(11)不可相对于外壳(6)或导向套筒(1)在轴向方向上被移动。此外，锁定环(11)在其内侧表面处包括联接齿部(11c)，其可与布置在旋转套筒(2)的接合元件(2a)的外侧表面处的配对联接齿部(2e)达到接合。在锁定环(11)的近端端部处布置有止挡面(11d)，其可与旋转套筒环形接片(2c)的远端侧面达到止挡接触。FIG. 1 shows an exploded view of an embodiment according to the invention of an injection device for administering liquid products. The injection device comprises a cartridge holder (8) which accommodates a cartridge (10), wherein the cartridge holder (8) is axially fixedly, in particular axially and radially fixedly, connected to the housing (6). connect. This connection can be configured as a snap connection. For this purpose, the cartridge holder (8) can have a cartridge holder projection (8a), which can be snapped into a housing recess (6a) provided on the housing (6). The housing (6) may preferably include a housing guide groove (6b) which is engageable with a cartridge holder guide tab (8b) arranged at the cartridge holder (8) to facilitate the insertion of the cartridge ( 10) The received cartridge holder (8) is inserted into the housing (6) in the proximal direction. At the distal end of the cartridge holder (8) there is provided a needle connection element (8c) which is provided for releasable fixation of an injection needle (not visible). Furthermore, the injection device comprises a cap (12) which can be connected to the cartridge holder (8) via a releasable connection. To this end, the cartridge holder (8) has a cartridge holder cam (8d) which can be locked into an annular groove (not visible) in the closure (12). Preferably, the annular groove (not visible) of the closure (12) can have a recess (not visible), so that the closure (12) can be arranged in a rotationally fixed manner relative to the cartridge holder (8). In addition, an elastically configured holding element (9) is provided. The holding element ( 9 ) is annular or sleeve-shaped. The retaining element (9) comprises a spring element (9a). The holding element ( 9 ) can likewise be designed as a spring element ( 9 a ). Furthermore, the holding element (9) comprises a clamping element (9b). The holding element (9) can likewise be configured as a clamping element (9b). The holding element (9) comprises a distal positioning element (9c) and a proximal positioning element (9d). Furthermore, the holding element (9) comprises a support element (9e). The support element (9e) serves to support the cartridge (10), in particular the cartridge edge (10a) at the proximal end of the cartridge (10). Furthermore, the injection device comprises a guide sleeve (1). The guide sleeve (1) is connected to the housing (6) in a rotationally fixed manner via the guide sleeve web (1c) arranged on the guide sleeve (1) and the groove (not visible) mounted on the housing (6) and via An inwardly protruding guide sleeve projection (1d) of the guide sleeve (1) is axially fixedly connected to a housing holding arm (6c; eg in FIG. 4a) mounted on the housing (6). Alternatively, the guide sleeve ( 1 ) and the housing ( 6 ) can be constructed in one piece. The guide sleeve (1) has an engagement element (1a) which can cooperate with the toothing of the threaded rod (3). Furthermore, the injection device comprises a rotary sleeve (2), which is connected axially fixedly and rotatably to the guide sleeve (1). For this purpose, the swivel sleeve (2) has a swivel sleeve annular web (2c), which can axially stop at its proximal side at the guide sleeve holding arm (1b), preferably at both guide sleeves At the sleeve holding arm (1b), the rotating sleeve edge (2d) can also form an axial stop contact with the guide sleeve end side (not visible) of the guide sleeve (1). The rotary sleeve (2) likewise comprises an engagement element (2a), which can cooperate with the toothing of the threaded rod (3). The toothing of the threaded rod (3) comprises a tooth (3a), preferably a plurality of teeth, particularly preferably four teeth. Furthermore, the threaded rod (3) has an external thread (3b), which forms a screw connection with an internal thread (6i, eg in FIG. 4a ) of the housing (6). Alternatively, an internal thread can be provided on the guide sleeve (1). The engagement mechanism of the engagement elements (2a, 1a) of the rotary sleeve (2) and of the guide sleeve (1) into the toothing of the threaded rod (3) is configured as a ratchet mechanism. The engagement elements (2a, 1a) of the rotary sleeve (2) and the guide sleeve (1) interact with the toothing of the threaded rod (3) in such a way that, at the determined dose setting (Aufdosieren) In this case and in the case of pouring out a determined dose, a clicking noise is produced. To prevent adjustment of further doses when the last dose has been poured out, the swivel sleeve (2) has a swivel sleeve stop (not visible) which can engage with a threaded rod stop (3c) arranged at the threaded rod (3) ) to produce a stop contact. Furthermore, the injection device comprises a dosing sleeve (4). The metering sleeve ( 4 ) is mounted in a rotationally fixed and axially displaceable manner relative to the housing ( 6 ) of the injection device via a metering sleeve web ( 4 a ) and a housing groove (not visible). The user can move the dosing sleeve (4) axially in the proximal direction by means of the dosing button (4c) arranged at the proximal end of the dosing sleeve (4), and by means of the The pour button (5) at the top moves axially in the distal direction. The pour button ( 5 ) is axially fixed, in particular axially fixed and rotationally fixed, connected via a pour button projection ( 5 a ) to the metering button ( 4 c ). In order to display the individual metering movements, the metering sleeve (4) preferably has a display (4d). A display ( 4d ) of the dosing cartridge ( 4 ) is visible through a housing window ( 6d ) arranged on the housing ( 6 ), wherein the position of the injection device is visible to the user. The dosing sleeve (4) is connected to the rotary sleeve (2) via a threaded connection. The inner side of the dosing sleeve (4) comprises a dosing sleeve thread (4b) which is in engagement with the rotating sleeve thread (2b) at the outer side of the rotating sleeve (2). Furthermore, the injection device comprises a locking ring (11) having ratchet teeth (11a) at its distal end, which is connected to the guide sleeve (1) via a detent arm (11b) of the locking ring (11). The ratchet teeth (11a) of the locking ring (11) engage into the ratchet teeth (not visible) of the guide sleeve (1), wherein the ratchet teeth (11a) of the locking ring (11) and the guide sleeve (1) The ratchet teeth (not visible) are configured in such a way that the ratchet teeth (11a) can slide past the guide sleeve (1) in the first direction of rotation relative to the ratchet teeth (not visible) of the guide sleeve (1) Ratchet teeth (not visible) and prevent relative rotation between the locking ring (11) and the guide sleeve (1) in the direction of rotation opposite to the first direction of rotation, ie in the second direction of rotation. The locking ring (11) cannot be moved in the axial direction relative to the housing (6) or the guide sleeve (1). Furthermore, the locking ring (11) comprises at its inside surface a coupling tooth (11c) reachable with a counter coupling tooth (2e) arranged at the outside surface of the engagement element (2a) of the rotating sleeve (2). join. Arranged at the proximal end of the locking ring (11) is a stop surface (11d), which can come into stop contact with the distal side of the rotary sleeve annular web (2c).
在图2a中示出了根据图1的注射装置的一部分的纵截面视图，其中，保持元件(9)借助于工具、尤其借助于挤压柱(Pressstempel)(13)在近端方向上被置入或被插入到注射装置的外壳(6)中。保持元件(9)由工具、尤其由挤压柱(13)容纳。该工具、尤其挤压柱(13)将保持元件(9)在近端方向上轴向引入到外壳(6)中。在此，工具、尤其挤压柱(13)具有挺杆元件(13a)且保持元件(9)具有配对挺杆元件(9f)。工具、尤其挤压柱(13)将保持元件(9)如此程度地插入到外壳(6)中，直至保持元件(9)至少在近端方向上被定位在外壳(6)处或中。优选地，工具、尤其挤压柱(13)可通过止挡到外壳(6)的外壳止挡面(6e)处将保持元件(9)定位在外壳(6)处或中。此外，该工具、尤其挤压柱(13)将保持元件(9)如此程度地引入到外壳(6)中，直至保持元件(9)至少在近端方向上在外壳(6)处或中经由力配合的和/或形状配合的连接被定位在外壳(6)处或中。如在图2b中所示出的那样，保持元件(9)的近端的定位元件(9d)可与外壳(6)的外壳圆柱体(6f)达到力配合的连接。在该位置中，保持元件(9)优选径向且/或轴向被预紧。保持元件(9)、尤其保持元件(9)的远端的定位元件(9c)的优选径向的预紧可用于在远端方向上将保持元件(9)定位在外壳(6)处或中。在将保持元件(9)至少在近端方向上定位在外壳(6)处或中之后，工具、尤其挤压柱(13)可从保持元件(9)中被拉出、尤其在远端方向上被拉出。FIG. 2 a shows a longitudinal section view of a part of the injection device according to FIG. 1 , wherein the retaining element ( 9 ) is positioned in the proximal direction by means of a tool, in particular by means of a press stem ( 13 ). into or inserted into the housing (6) of the injection device. The holding element (9) is accommodated by the tool, in particular by the extrusion cylinder (13). The tool, in particular the pressing cylinder ( 13 ), axially introduces the holding element ( 9 ) into the housing ( 6 ) in the proximal direction. Here, the tool, in particular the pressing cylinder ( 13 ), has a tappet element ( 13 a ) and the holding element ( 9 ) has a counter tappet element ( 9 f ). The tool, in particular the pressing cylinder ( 13 ), inserts the retaining element ( 9 ) into the housing ( 6 ) until the retaining element ( 9 ) is positioned on or in the housing ( 6 ), at least in the proximal direction. Preferably, the tool, in particular the pressing pin ( 13 ), can position the holding element ( 9 ) on or in the housing ( 6 ) by abutting against a housing stop surface ( 6 e ) of the housing ( 6 ). Furthermore, the tool, in particular the pressing pin (13), introduces the retaining element (9) into the housing (6) to such an extent that the retaining element (9) passes at least in the proximal direction on or in the housing (6). A non-positive and/or form-fitting connection is positioned on or in the housing (6). As shown in FIG. 2 b , the proximal positioning element ( 9 d ) of the holding element ( 9 ) can be connected non-positively to the housing cylinder ( 6 f ) of the housing ( 6 ). In this position, the retaining element ( 9 ) is preferably prestressed radially and/or axially. The preferably radial pretensioning of the holding element (9), in particular of the distal positioning element (9c) of the holding element (9), can be used to position the holding element (9) on or in the housing (6) in the distal direction . After positioning the holding element (9) at or in the housing (6) at least in the proximal direction, the tool, in particular the pressing post (13), can be pulled out of the holding element (9), in particular in the distal direction is pulled out.
在图3中示出了根据图1的注射装置的一部分的纵截面视图，其中，保持元件(9)借助于工具、尤其借助于挤压柱(13)被置入或插入在注射装置的外壳(6)中且通过摩擦配合和/或形状配合在远端和近端方向上被定位在外壳(6)处或中。保持元件(9)通过近端的定位元件(9d)在外壳(6)的外壳圆柱体(6f)处的挤压经由力配合的连接被定位在外壳(6)处或中。此外，保持元件(9)由于保持元件(9)、尤其保持元件(9)的远端的定位元件(9c)的至少部分卸压通过在远端的定位元件(9c)与外壳(6)的外壳凹口面(6h)之间的止挡接触经由形状配合的连接在远端方向上被定位在外壳(6)处或中。特别优选地，外壳凹口面(6h)可构成外壳凹口(6a)的一部分。备选地，保持元件(9)可经由在远端的定位元件(9c)与外壳(6)、尤其外壳内面(6g)之间的力配合的连接、尤其摩擦连接在远端方向上被定位在外壳(6)处或中。FIG. 3 shows a longitudinal section view of a part of the injection device according to FIG. 1 , wherein the retaining element ( 9 ) is inserted or inserted into the housing of the injection device by means of a tool, in particular by means of a pressing pin ( 13 ). ( 6 ) and is positioned at or in the housing ( 6 ) in distal and proximal direction by a friction fit and/or form fit. The holding element ( 9 ) is positioned on or in the housing ( 6 ) via a non-positive connection by pressing the proximal positioning element ( 9 d ) on the housing cylinder ( 6 f ) of the housing ( 6 ). Furthermore, the retaining element (9) is at least partially depressurized by the retaining element (9), especially the distal positioning element (9c) of the retaining element (9) through the contact between the distal positioning element (9c) and the housing (6). The stop contact between the housing recess faces ( 6h ) is positioned at or in the housing ( 6 ) in the distal direction via a form-fit connection. Particularly preferably, the housing recess surface ( 6h ) can form part of the housing recess ( 6a ). Alternatively, the retaining element (9) can be positioned in the distal direction via a non-positive connection, in particular a frictional connection, between the distal positioning element (9c) and the housing (6), in particular the inner housing surface (6g). At or in the housing (6).
在另一步骤中，以卡式瓶(10)容纳的卡式瓶支架(8)在近端方向上被置入或插入到注射装置的以保持元件(9)容纳的外壳(6)中，如在图4a中所示出的那样。In a further step, the cartridge holder (8) accommodated with the cartridge (10) is placed or inserted in the proximal direction into the housing (6) of the injection device accommodated with the retaining element (9), As shown in Figure 4a.
在此，卡式瓶(10)的近端的卡式瓶边缘(10a)与保持元件(9)的支撑元件(9e)达到止挡接触。特别优选地，保持元件(9)的支撑元件(9e)可充当保持元件(9)的配对挺杆元件(9f)。在插入以卡式瓶(10)容纳的卡式瓶支架(8)的情形中，保持元件(9)、尤其保持元件(9)的弹簧元件(9a)被预紧、尤其被弹性预紧。以卡式瓶(10)容纳的卡式瓶支架(8)被如此程度地置入或插入到外壳(6)中，直至卡式瓶支架(8)经由卡扣连接与外壳(6)轴向固定地相连接，尤其轴向固定地且旋转固定地与外壳(6)相连接，如在图4b和4c中所示出的那样。在保持元件(9)的远端的定位元件(9c)与外壳(6)之间的力配合的或形状配合的连接被解开。卡式瓶(10)经由保持元件(9)、尤其经由保持元件(9)的弹簧元件(9a)借助于在远端方向上起作用的力被无间隙地保持在卡式瓶支架(8)处或中。保持元件(9)在近端方向上被定位在外壳(6)处或中且在远端方向上被支撑在卡式瓶处或中。保持元件(9)、尤其保持元件(9)的夹紧元件(9b)将在轴向方向上起作用的摩擦力施加到外壳(6)上以用于将卡式瓶(10)固定在卡式瓶支架(8)处或中，其中，保持元件(9)、尤其保持元件(9)的夹紧元件(9b)的在轴向方向上起作用的摩擦力相对保持元件(9)、尤其保持元件(9)的弹簧元件(9a)的在远端方向上起作用的力起作用。保持元件(9)、尤其保持元件(9)的夹紧元件(9b)的在轴向方向上起作用的摩擦力用于构成在保持元件(9)与外壳(6)之间的摩擦配合的连接。特别优选地，在远端方向上起作用的力至少部分、优选完全通过在轴向方向上起作用的摩擦力来补偿。Here, the proximal cartridge edge ( 10 a ) of the cartridge ( 10 ) comes into stop contact with the support element ( 9 e ) of the holding element ( 9 ). Particularly preferably, the support element (9e) of the holding element (9) can act as a counterpart tappet element (9f) of the holding element (9). During insertion into a cartridge holder ( 8 ) accommodated by a cartridge ( 10 ), the retaining element ( 9 ), in particular the spring element ( 9 a ) of the retaining element ( 9 ), is prestressed, in particular elastically prestressed. The cartridge holder (8) accommodated in the cartridge (10) is placed or inserted into the housing (6) to such an extent that the cartridge holder (8) is axially connected to the housing (6) via a snap-fit connection. It is fixedly connected, in particular axially fixed and rotationally fixed, to the housing ( 6 ), as shown in FIGS. 4 b and 4 c . The non-positive or positive connection between the positioning element ( 9 c ) at the distal end of the holding element ( 9 ) and the housing ( 6 ) is released. The cartridge (10) is held without play in the cartridge holder (8) via the holding element (9), in particular via the spring element (9a) of the holding element (9) by means of a force acting in the distal direction at or in. The retaining element (9) is positioned at or in the housing (6) in the proximal direction and supported at or in the cartridge in the distal direction. The retaining element (9), in particular the clamping element (9b) of the retaining element (9), exerts a frictional force acting in the axial direction on the housing (6) for securing the cartridge (10) on the cartridge At or in the bottle holder (8), wherein the frictional force acting in the axial direction of the holding element (9), especially the clamping element (9b) of the holding element (9) is relative to the holding element (9), especially The force acting in the distal direction of the spring element (9a) of the retaining element (9) acts. The frictional force acting in the axial direction of the retaining element (9), in particular the clamping element (9b) of the retaining element (9), serves to form a friction fit between the retaining element (9) and the housing (6) connect. Particularly preferably, the force acting in the distal direction is at least partially, preferably completely, compensated by the friction force acting in the axial direction.
患者可在另一步骤中利用根据本发明的注射装置以用于施用液体产品，其中，配量套筒(4)在初始位置中。在外壳(6)中轴向可移动且抗扭地被支承的配量套筒(4)在注射器中被推入，其中，被安装在配量套筒(4)处的显示器(4d)透过外壳窗口(6d)可见且给用户显示注射装置在初始位置中。配量套筒(4)经由配量套筒螺纹(4b)与旋转套筒(2)的旋转套筒螺纹(2b)在螺纹接合中。旋转套筒(2)的径向向外伸出的突起(不可见)与导向套筒(1)的第一径向向内伸出的突起(不可见)处在止挡接触中、尤其在旋转止挡接触中。被安装在旋转套筒(2)的接合元件(2a)处的头部(不可见)与螺纹杆(3)的齿部在接合中。为此，旋转套筒(2)的接合元件(2a)的头部(不可见)在两个相邻齿(3a)之间接合到螺纹杆(3)的齿隙(不可见)中，即在齿(3a)的陡峭的侧面(不可见)与螺纹杆(3)的相邻齿(3a)的平坦的侧面(不可见)之间。此外，设置在导向套筒(1)的接合元件(1a)处的头部(不可见)同样与螺纹杆(3)的齿部在接合中。为此，导向套筒(1)的接合元件(1a)的头部(不可见)同样在两个相邻的齿(3a)之间接合到螺纹杆(3)的齿隙(不可见)中。导向套筒的接合元件(1a)的头部(不可见)处在齿(3a)的陡峭的侧面(不可见)与螺纹杆(3)的相邻齿(3a)的平坦的侧面(不可见)之间。In a further step the patient can utilize the injection device according to the invention for administering the liquid product, wherein the dosing sleeve ( 4 ) is in the initial position. The dosing sleeve (4), which is axially displaceable and mounted in a rotationally fixed manner in the housing (6), is pushed into the syringe, wherein the display (4d) mounted on the dosing sleeve (4) sees through the Visible through the housing window (6d) and shows the user that the injection device is in the initial position. The metering sleeve (4) is in threaded engagement with the rotary sleeve thread (2b) of the rotary sleeve (2) via the metering sleeve thread (4b). The radially outwardly protruding projection (not visible) of the rotary sleeve (2) is in stop contact with the first radially inwardly protruding projection (not visible) of the guide sleeve (1), especially at The rotary stop is in contact. A head (not visible) mounted at the engagement element (2a) of the rotating sleeve (2) is in engagement with the toothing of the threaded rod (3). To this end, the head (not visible) of the engaging element (2a) of the rotating sleeve (2) engages into the tooth gap (not visible) of the threaded rod (3) between two adjacent teeth (3a), i.e. Between the steep side (not visible) of the tooth (3a) and the flat side (not visible) of the adjacent tooth (3a) of the threaded rod (3). Furthermore, a head (not visible) arranged on the engagement element ( 1 a ) of the guide sleeve ( 1 ) also engages with the toothing of the threaded rod ( 3 ). To this end, the head (not visible) of the engaging element (1a) of the guide sleeve (1) likewise engages in the tooth space (not visible) of the threaded rod (3) between two adjacent teeth (3a) . The head (not visible) of the engaging element (1a) of the guide sleeve is between the steep side (not visible) of the tooth (3a) and the flat side (not visible) of the adjacent tooth (3a) of the threaded rod (3). )between.
为了调整或拉起剂量，用户在近端方向上拉动配量按钮(4c)。在此，配量套筒(4)轴向在近端方向上被移动。由于在配量套筒(4)与旋转套筒(2)之间的螺纹接合，旋转套筒(2)在第一转动方向上转动直至旋转套筒(2)的突起(不可见)与导向套筒(1)的第二径向向内伸出的突起(不可见)在止挡接触中。在此，旋转套筒(2)的接合元件(2a)的头部(不可见)的平坦的侧面(不可见)滑动经过螺纹杆(3)的齿(3a)的平坦的侧面(3a')且在此到达相邻的齿隙(不可见)中。导向套筒(1)的接合元件(1a)的头部(不可见)的陡峭的侧面(不可见)与螺纹杆(3)的齿(3a)的陡峭的侧面(不可见)在止挡接触中，从而螺纹杆(3)被抗扭地保持。被安装在配量套筒(4)处的显示器(4d)通过外壳窗口(6d)给用户显示注射装置在被拉起的位置中。To adjust or pull up the dose, the user pulls the dose button (4c) in the proximal direction. Here, the metering sleeve ( 4 ) is displaced axially in the proximal direction. Due to the threaded engagement between the dosing sleeve (4) and the swivel sleeve (2), the swivel sleeve (2) turns in the first rotational direction until the protrusion (not visible) of the swivel sleeve (2) meets the guide A second radially inwardly projecting protrusion (not visible) of the sleeve (1) is in stop contact. Here, the flat side (not visible) of the head (not visible) of the engagement element (2a) of the rotating sleeve (2) slides past the flat side (3a') of the tooth (3a) of the threaded rod (3) And here it goes into the adjacent tooth gap (not visible). The steep side (not visible) of the head (not visible) of the engaging element (1a) of the guide sleeve (1) comes into contact with the steep side (not visible) of the tooth (3a) of the threaded rod (3) at the stop , so that the threaded rod (3) is held in a rotationally fixed manner. A display (4d) mounted on the dosing sleeve (4) shows the user via a housing window (6d) that the injection device is in the raised position.
在调整或拉起剂量的情形中，旋转套筒(2)的接合元件(2a)被径向偏转。在此，旋转套筒(2)的配对联接齿部(2e)与锁定环(11)的联接齿部(11c)在接合中。通过在旋转套筒(2)与锁定环(11)之间的联接，锁定环(11)和旋转套筒(2)在第一转动方向上相对于外壳(6)或导向套筒(1)被转动。锁定环(11)的棘轮齿(11a)滑动经过导向套筒(1)的棘轮齿部(不可见)。锁定环(11)的棘轮齿(11a)仅可在第一转动方向上相对于导向套筒(1)滑动经过导向套筒(1)的棘轮齿部(1g)，而在第二转动方向上的相对转动被防止。旋转套筒(2)的接合元件(2a)被如此长地径向偏转，直至接合元件的头部(不可见)到达螺纹杆(3)的齿隙(不可见)中，或者直至经确定的剂量完全被调整或拉起。因此可防止如下，即，不完全被调整或拉起的剂量可被倒出。In case of adjusting or pulling up the dose, the engagement element (2a) of the rotating sleeve (2) is deflected radially. Here, the mating coupling toothing ( 2 e ) of the rotary sleeve ( 2 ) is in engagement with the coupling toothing ( 11 c ) of the locking ring ( 11 ). Through the coupling between the rotating sleeve (2) and the locking ring (11), the locking ring (11) and the rotating sleeve (2) are relative to the housing (6) or the guide sleeve (1) in the first rotational direction is turned. The ratchet teeth (11a) of the locking ring (11) slide past the ratchet teeth of the guide sleeve (1) (not visible). The ratchet teeth (11a) of the locking ring (11) can only slide past the ratchet teeth (1g) of the guide sleeve (1) in the first direction of rotation relative to the guide sleeve (1) and in the second direction of rotation relative rotation is prevented. The engagement element (2a) of the rotary sleeve (2) is deflected radially until the head of the engagement element (not visible) reaches the tooth gap (not visible) of the threaded rod (3), or until a determined The dose is adjusted or pulled up entirely. It can thus be prevented that an incompletely adjusted or drawn-up dose can be poured out.
配量套筒(4)的拉起运动和螺纹杆(3)的倒出运动被转换。在配量套筒(4)与旋转套筒(2)之间的螺纹连接(4b,2b)的螺纹升程(Gewindesteigung)大于在螺纹杆(3)与外壳(6)之间的螺纹连接(3b,6i)的螺纹升程。The pull-up movement of the metering sleeve (4) and the pour-out movement of the threaded rod (3) are converted. The screw connection (4b, 2b) between the metering sleeve (4) and the rotary sleeve (2) has a greater thread lift (Gewindesteigung) than the screw connection ( 3b, 6i) screw lift.
为了倒出经确定的剂量，用户在远端方向上按压倒出按钮(5)，其中，配量套筒(4)在远端方向上被轴向移动。旋转套筒(2)在相反于第一转动方向的转动方向上、即在第二转动方向上转动，直至旋转套筒(2)的突起(不可见)与导向套筒(1)的第一径向向内伸出的突起(不可见)到达止挡接触。旋转套筒(2)的接合元件(2a)的头部的陡峭的侧面(不可见)与螺纹杆(3)的齿(3a)的陡峭的侧面(不可见)在止挡接触中且将扭矩传递到螺纹杆(3)上。螺纹杆(3)由此由于在外壳(6)的内螺纹(6i)与螺纹杆(3)的外螺纹(3b)之间的螺纹连接在远端方向上拧紧。在此，旋转套筒(2)的接合元件(2a)的头部(不可见)轴向沿着螺纹杆(3)的齿隙(不可见)滑动。锁定环(11)的联接齿部(11c)与旋转套筒(2)的配对联接齿部(2e)分离，从而旋转套筒(2)相对于锁定环(11)可在第二转动方向上转动。锁定环(11)的棘轮齿(11c)伸出到导向套筒(1)的棘轮齿部(1g)中。导向套筒(1)的头部(不可见)的平坦的侧面滑动经过螺纹杆的齿(不可见)的平坦的侧面。在此，经由被轴向固定地安装在螺纹杆(3)处的法兰(7)在远端方向上顶撞由卡式瓶(10)容纳的塞子(10b，例如在图4a中)。塞子(10b，例如在图4a中)可经由被固定在卡式瓶支架处的注射针(不可见)挤出液体产品。To pour out the determined dose, the user presses the pour button (5) in the distal direction, wherein the dosing sleeve (4) is moved axially in the distal direction. The swivel sleeve (2) is rotated in the opposite direction of rotation to the first, i.e. in the second direction of rotation, until the projection (not visible) of the swivel sleeve (2) meets the first Radially inwardly protruding projections (not visible) reach the stop contacts. The steep side (not visible) of the head of the engaging element (2a) of the rotating sleeve (2) is in stop contact with the steep side (not visible) of the tooth (3a) of the threaded rod (3) and torque Transfer to the threaded rod (3). The threaded rod (3) is thus screwed in the distal direction due to the threaded connection between the internal thread (6i) of the housing (6) and the external thread (3b) of the threaded rod (3). Here, the head (not visible) of the engagement element (2a) of the rotating sleeve (2) slides axially along the tooth gap (not visible) of the threaded rod (3). The coupling teeth (11c) of the locking ring (11) are separated from the mating coupling teeth (2e) of the rotary sleeve (2), so that the rotary sleeve (2) can be rotated in a second direction relative to the locking ring (11) turn. The ratchet teeth (11c) of the locking ring (11) protrude into the ratchet teeth (1g) of the guide sleeve (1). The flat sides of the head (not visible) of the guide sleeve (1) slide over the flat sides of the teeth (not visible) of the threaded rod. Here, the bung ( 10 b , eg in FIG. 4 a ) received by the cartridge ( 10 ) is abutted in the distal direction via the flange ( 7 ), which is axially fixedly mounted on the threaded rod ( 3 ). The stopper (10b, eg in Fig. 4a) can squeeze out the liquid product through an injection needle (not visible) secured at the cartridge holder.
在最后的剂量从注射装置中被倒出之后，旋转套筒(2)的两个旋转套筒止挡(不可见)与螺纹杆(3)的相应的两个螺纹杆止挡(3c)在止挡接触中。因此，进一步的剂量不可经由配量套筒(4)被拉起，因为旋转套筒(2)的旋转被阻止。After the last dose has been poured out of the injection device, the two rotary sleeve stops (not visible) of the rotary sleeve (2) are in contact with the corresponding two threaded rod stops (3c) of the threaded rod (3). The stop is in contact. Consequently, further doses cannot be pulled up via the dosing sleeve (4), since the rotation of the rotary sleeve (2) is blocked.
附图标记列表List of reference signs
1 导向套筒1 guide sleeve
1a 接合元件1a Engagement elements
1b 导向套筒保持臂1b guide sleeve retaining arm
1c导向套筒接片1c Guide sleeve tab
1d 导向套筒突起1d Guide sleeve protrusion
2 旋转套筒2 rotating sleeve
2a 接合元件2a Engagement elements
2b 旋转套筒螺纹2b Rotary sleeve thread
2c旋转套筒环形接片2c Swivel sleeve ring joint
2d 旋转套筒棱边2d rotating sleeve edge
2e 配对联接齿部2e Mating coupling teeth
3 螺纹杆3 threaded rod
3a 齿3a teeth
3b 外螺纹3b external thread
3c 螺纹杆止挡3c Threaded rod stop
4 配量套筒4 dosing sleeve
4a 配量套筒接片4a Metering sleeve adapter
4b 配量套筒螺纹4b Metering sleeve thread
4c 配量按钮4c Dosing button
4d 显示器4d display
5 倒出按钮5 pour button
5a 倒出按钮突起5a Pour button protrusion
6 外壳6 shell
6a 外壳凹口6a Housing notch
6b 外壳导向槽6b housing guide groove
6c 外壳保持臂6c Housing Retention Arm
6d 外壳窗口6d shell window
6e 外壳止挡面6e Housing stop surface
6f 外壳圆柱体6f shell cylinder
6g 外壳内面6g shell inside
6h 外壳凹口面6h Housing notched face
7 法兰7 flange
8 卡式瓶支架8 Cartridge Holder
8a 卡式瓶支架突起8a Cartridge holder protrusion
8b 卡式瓶支架导向8b Cartridge Holder Guide
8c 针连接元件8c pin connection element
8d 卡式瓶支架凸轮8d Cartridge Holder Cam
9 保持元件9 holding element
9a 弹簧元件9a Spring element
9b 夹紧元件9b Clamping element
9c 远端的位置元件9c Distal positional element
9d 近端的位置元件9d Proximal position element
9e 支撑元件9e Support element
9f 配对挺杆元件9f paired tappet element
10 卡式瓶10 cartridges
10a 近端的卡式瓶边缘10a Proximal Cartridge Edge
10b 塞子10b Plug
11锁定环11 locking ring
11a 棘轮齿11a Ratchet teeth
11b 锁销臂11b Lock pin arm
11c 联接齿部11c Coupling gear
11d 止挡面11d Stop surface
12 封盖12 caps
13工具，挤压柱13 tools, extrusion column
13a挺杆元件13a Tappet element
Claims (15)
Translated fromChineseApplications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH01168/20ACH717876A2 (en) | 2020-09-16 | 2020-09-16 | Injection device for administering a fluid product. |
| CHCH01168/20 | 2020-09-16 | ||
| PCT/EP2021/074747WO2022058221A1 (en) | 2020-09-16 | 2021-09-09 | Injection device for administering a liquid product |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN116075330Atrue CN116075330A (en) | 2023-05-05 |
Family
ID=77897629
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202180062930.8APendingCN116075330A (en) | 2020-09-16 | 2021-09-09 | Injection devices for administering liquid products |
Country Status (4)
| Country | Link |
|---|---|
| EP (1) | EP4213917A1 (en) |
| CN (1) | CN116075330A (en) |
| CH (1) | CH717876A2 (en) |
| WO (1) | WO2022058221A1 (en) |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20070021718A1 (en)* | 2005-05-24 | 2007-01-25 | Stefan Burren | Plastic spring |
| WO2010043533A1 (en)* | 2008-10-13 | 2010-04-22 | Sanofi-Aventis Deutschland Gmbh | Drug delivery device and method of manufacturing a drug delivery device |
| US20170348489A1 (en)* | 2015-02-26 | 2017-12-07 | Tecpharma Licensing Ag | Carpoule holder for receiving a carpoule and fastening to a drive mechanism and/or metering mechanism and/or housing of an injection device |
- 2020
- 2020-09-16CHCH01168/20Apatent/CH717876A2/ennot_activeApplication Discontinuation
- 2021
- 2021-09-09EPEP21773770.9Apatent/EP4213917A1/enactivePending
- 2021-09-09CNCN202180062930.8Apatent/CN116075330A/enactivePending
- 2021-09-09WOPCT/EP2021/074747patent/WO2022058221A1/ennot_activeCeased
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20070021718A1 (en)* | 2005-05-24 | 2007-01-25 | Stefan Burren | Plastic spring |
| WO2010043533A1 (en)* | 2008-10-13 | 2010-04-22 | Sanofi-Aventis Deutschland Gmbh | Drug delivery device and method of manufacturing a drug delivery device |
| US20170348489A1 (en)* | 2015-02-26 | 2017-12-07 | Tecpharma Licensing Ag | Carpoule holder for receiving a carpoule and fastening to a drive mechanism and/or metering mechanism and/or housing of an injection device |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2022058221A1 (en) | 2022-03-24 |
| CH717876A2 (en) | 2022-03-31 |
| EP4213917A1 (en) | 2023-07-26 |
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