The evaluation method comprises the steps of setting 10 sensory evaluators, setting an evaluation table for each person, scoring after each person experiences the product by adopting a dark evaluation scoring mode, removing a highest score and a lowest score, and taking an average value.

Table 2 sensory evaluation table

As can be seen from Table 2, the buccal preparation prepared in example 1 exhibited excellent irritation, pungency, bitterness, satisfaction and flavor. In the example, the addition of vitamin B3, vitamin B15 and taurine does not affect the taste, and compared with the control group, the examples 1-2 have improved irritation, pungency and bitter taste.

2. Evaluation of anti-fatigue Effect

The method is obvious and effective: the working state is obviously improved, and the movement capability is obviously enhanced;

the improvement is that: the working state is improved, and the movement capability is enhanced;

no obvious difference exists between the use and the use: fatigue symptoms were not improved.

Table 3 fatigue resistance evaluation table

As can be seen in conjunction with table 3, the oral formulations of examples 1-2 were significantly more fatigue resistant than the control, which may be associated with examples containing vitamin B3, vitamin B12, vitamin B15, taurine, tyrosine, vitamin a, vitamin E, etc., whereas example 1 was superior to example 2, which may be associated with higher functional levels. The control group contains nicotine, so that fatigue can be relieved to a certain extent, but the effect is not obvious.

The foregoing description of the preferred embodiments of the invention is not intended to be limiting, but rather is intended to cover all modifications, equivalents, and alternatives falling within the spirit and principles of the invention.

Claims

1. The buccal preparation for relieving fatigue is characterized by comprising an adhesive, a functional additive, a sweetener, a flavoring agent, a filler, a disintegrating agent, a preservative and water;

2. The fatigue-relieving buccal formulation according to claim 1, wherein the binder is a nicotine salt in an amount of 0.3 to 6 parts by weight.

3. The fatigue-relieving buccal formulation of claim 2, wherein the nicotine salt is nicotine benzoate and the nicotine benzoate is present in an amount of 1 to 3 parts.

4. The fatigue-relieving buccal preparation according to claim 2, wherein the functional additive comprises at least vitamin B3 and tyrosine in an amount of 1 to 10 parts.

5. The fatigue-relieving buccal preparation according to claim 4, wherein the functional additive further comprises vitamin B15, taurine and vitamin a, wherein the amount of vitamin B15 is 0 to 10 parts, the amount of taurine is 0 to 10 parts, and the amount of vitamin a is 0 to 15 parts.

6. The fatigue-relieving buccal preparation according to claim 2, wherein the sweetener comprises at least erythritol, and the erythritol is used in an amount of 1 to 10 parts.

7. The fatigue-relieving buccal formulation of claim 6, wherein the sweetener further comprises xylitol, maltitol, sorbitol, isomalt in an amount of: 0-10 parts of xylitol, 0-10 parts of maltitol, 0-10 parts of sorbitol and 0-10 parts of isomaltulose alcohol.

8. The fatigue-alleviating buccal preparation according to claim 1, wherein the flavoring agent is one or more of peppermint essence, strawberry essence, watermelon essence; the dosage of the components is as follows: 0-10 parts of mint essence, 0-10 parts of strawberry essence and 0-10 parts of watermelon essence;

the filler at least comprises microcrystalline cellulose sodium and pregelatinized starch, and the dosage of the microcrystalline cellulose sodium and the pregelatinized starch is as follows: 5-30 parts of microcrystalline cellulose sodium and 5-30 parts of pregelatinized starch;

the disintegrating agent at least comprises citric acid and sodium bicarbonate, and the dosage of the citric acid and the sodium bicarbonate is as follows: 1-5 parts of citric acid and 3-10 parts of sodium bicarbonate;

the preservative is potassium sorbate, and the dosage is as follows: 0.1-1 part of potassium sorbate;

the water is distilled water, and the dosage is as follows: 20-50 parts.

9. The fatigue-relieving buccal preparation according to claim 1, wherein the buccal preparation comprises a humectant, wherein the humectant is glycerol, and the dosage is as follows: 0.1-10 parts.

10. A preparation method of a buccal preparation for relieving fatigue is characterized by comprising the following steps:

1) Taking water;

2) Slowly adding a filler, a disintegrating agent, a sweetener, a preservative and a functional additive into water, uniformly stirring by using a magnetic stirrer at normal temperature for more than 30 minutes, drying, crushing by using a crusher, and sieving by using a 60-mesh sieve;

3) Mixing binder, humectant and correctant uniformly, and mixing the obtained solution uniformly.

4) Adding the liquid in the step 3) into the powder obtained in the step 2), and stirring for 30min;