CN115480066A - Automatic sampling sample analyzer - Google Patents

Abstract

The invention discloses a full-automatic sample feeding sample analyzer, which comprises an automatic sample feeding component, a sampling component, a reaction component, a detection component and a blending device arranged between the automatic sample feeding component and the sampling component, wherein the blending device comprises a venous blood blending component and a peripheral blood blending component, the peripheral blood blending component moves to a receiving position or a blending position along a blending path, and in the receiving position, a peripheral blood test tube to be blended is placed in the peripheral blood blending component or the blended peripheral blood test tube is moved away from the peripheral blood blending component; and at the mixing position, the peripheral blood test tube placed on the peripheral blood mixing component vibrates to mix the peripheral blood uniformly, the mixed sample and the detection reagent are mixed in the reaction component to form a sample liquid to be detected, and the sample liquid to be detected obtains a sample detection result through the detection component.

Description

Translated fromChinese

全自动进样样本分析仪Automatic sampling sample analyzer

技术领域technical field

本发明涉及医疗器械技术领域，特别是涉及一种全自动进样样本分析仪。The invention relates to the technical field of medical devices, in particular to an automatic sample analyzer for sample introduction.

背景技术Background technique

人类生理和病理的变化往往会引起血液组分的变化，对血液的检测分析可以为医生的诊疗提供依据。样本分析仪是最常用的血细胞分析仪，其借助各种试剂对血液样本中的细胞进行统计分析。Changes in human physiology and pathology often cause changes in blood components, and the detection and analysis of blood can provide a basis for doctors' diagnosis and treatment. The sample analyzer is the most commonly used blood cell analyzer, which performs statistical analysis on the cells in the blood sample by means of various reagents.

目前全自动进样血细胞分析仪只适用于静脉血的自动检测，对于末梢血的检测，由于采血量比较少，现有的血细胞分析仪内的混匀装置不适应于末梢血混匀。如此，需要操作人员首先将承载有末梢血血样的试管手动进行混匀，然后将混匀好末梢血血样的试管放在血细胞分析仪的采样针下，采样针将混匀好的末梢血血样吸入血细胞分析仪中检测分析。也就是说，现有血细胞分析仪在用于末梢血检测时只能手动进样，操作繁琐、效率低下。At present, the automatic sample-injecting blood cell analyzer is only suitable for automatic detection of venous blood. For the detection of peripheral blood, due to the relatively small amount of blood collected, the mixing device in the existing blood cell analyzer is not suitable for mixing peripheral blood. In this way, the operator first needs to manually mix the test tube containing the peripheral blood sample, and then put the mixed test tube under the sampling needle of the hematology analyzer, and the sampling needle will suck the mixed peripheral blood sample Detection and analysis in blood cell analyzer. That is to say, when the existing blood cell analyzer is used for peripheral blood detection, it can only manually inject samples, which is cumbersome and inefficient.

发明内容Contents of the invention

有鉴于此，提供一种简单高效的全自动进样样本分析仪。In view of this, a simple and efficient automatic sample analyzer for sample injection is provided.

本发明提供一种全自动进样样本分析仪，包括自动进样组件、采样组件、反应组件、检测组件以及设置于所述自动进样组件和采样组件之间的混匀装置，所述混匀装置包括静脉血混匀组件和末梢血混匀组件，所述末梢血混匀组件沿一混匀路径移动至接收位或混匀位，在所述接收位，待混匀的末梢血试管被放置于所述末梢血混匀组件或者混匀后的末梢血试管从所述末梢血混匀组件被移走；在所述混匀位，放置于所述末梢血混匀组件上的末梢血试管振动以将末梢血混匀，混匀后的样本和检测试剂在所述反应组件混合形成待测样本液，待测样本液通过所述检测组件得到样本检测结果。The invention provides a fully automatic sampling sample analyzer, comprising an automatic sampling component, a sampling component, a reaction component, a detection component and a mixing device arranged between the automatic sampling component and the sampling component, the mixing The device includes a venous blood mixing component and a peripheral blood mixing component, and the peripheral blood mixing component moves along a mixing path to a receiving position or a mixing position, and at the receiving position, the peripheral blood test tube to be mixed is placed The peripheral blood mixing component or the mixed peripheral blood test tube is removed from the peripheral blood mixing component; at the mixing position, the peripheral blood test tube placed on the peripheral blood mixing component vibrates The peripheral blood is mixed evenly, and the mixed sample and detection reagent are mixed in the reaction component to form a sample liquid to be tested, and the sample liquid to be tested passes through the detection component to obtain a sample detection result.

进一步地，所述混匀路径沿所述全自动进样样本分析仪的左右方向设置，所述混匀路径上还包括初始位，在所述初始位，所述末梢血混匀组件和所述反应组件在左右方向上错开；或者，所述混匀路径沿所述全自动进样样本分析仪的前后方向设置，所述末梢血混匀组件和所述反应组件在左右方向上错开。Further, the mixing path is set along the left and right direction of the fully automatic sampling sample analyzer, and the mixing path also includes an initial position, and at the initial position, the peripheral blood mixing component and the The reaction components are staggered in the left and right direction; or, the mixing path is set along the front and back direction of the automatic sampling sample analyzer, and the peripheral blood mixing component and the reaction component are staggered in the left and right direction.

进一步地，所述初始位与所述混匀位为同一位置；或者，所述初始位与所述混匀位为两个不同的位置。Further, the initial position and the mixing position are at the same position; or, the initial position and the mixing position are two different positions.

进一步地，所述自动进样组件沿一进样路径移动向所述全自动进样样本分析仪运送试管，所述进样路径平行于所述混匀路径且低于所述混匀路径；或者，所述进样路径垂直于所述混匀路径且低于所述混匀路径。Further, the automatic sampling assembly moves along a sampling path to transport the test tube to the automatic sampling sample analyzer, and the sampling path is parallel to the mixing path and lower than the mixing path; or , the sample injection path is perpendicular to the mixing path and lower than the mixing path.

进一步地，所述采样组件沿一分样路径移动吸取样本并将所吸取的样本分注至所述反应组件，所述分样路径平行于所述混匀路径且高于所述混匀路径；或者，所述分样路径垂直于所述混匀路径且高于所述混匀路径。Further, the sampling component moves along a sample dividing path to draw a sample and distribute the drawn sample to the reaction component, the sample dividing path is parallel to the mixing path and higher than the mixing path; Or, the sampling path is perpendicular to the mixing path and higher than the mixing path.

进一步地，还包括转运组件，所述转运组件沿一转运路径移动以将试管由所述混匀装置向所述采样组件转运，所述转运路径与所述分样路径垂直并位于所述分样路径的下方。Further, it also includes a transfer assembly, the transfer assembly moves along a transfer path to transfer the test tube from the mixing device to the sampling assembly, the transfer path is perpendicular to the sample dividing path and is located in the sample dividing path. below the path.

进一步地，所述静脉血混匀组件包括抓手，所述抓手上下移动以抓取所述自动进样组件运送的试管，当所述抓手抓取的试管为静脉血试管时，所述抓手将所抓取的静脉血试管旋转混匀或者颠倒混匀；当所述抓手抓取的试管为末梢血试管时，所述末梢血混匀组件移动至所述接收位来承接所述抓手所抓取的末梢血试管。Further, the venous blood mixing assembly includes a gripper, and the gripper moves up and down to grab the test tube transported by the automatic sampling assembly. When the test tube grasped by the gripper is a venous blood test tube, the The grasper rotates or inverts the grasped venous blood test tube; when the test tube grasped by the grasper is a peripheral blood test tube, the peripheral blood mixing component moves to the receiving position to receive the The peripheral blood test tube grasped by the gripper.

进一步地，所述末梢血混匀组件包括有感应片，所述感应片与光耦配合以检测所述末梢血混匀组件的位置。Further, the peripheral blood mixing component includes a sensing piece, and the sensing piece cooperates with an optical coupler to detect the position of the peripheral blood mixing component.

进一步地，所述末梢血混匀组件包括振动板和设置于所述振动板上方的限位板，所述振动板上设置有混匀座以承接末梢血试管，所述限位板包括套接所述末梢血试管的限位部。Further, the peripheral blood mixing assembly includes a vibrating plate and a limiting plate arranged above the vibrating plate, the vibrating plate is provided with a mixing seat to receive the peripheral blood test tube, and the limiting plate includes a socket The limiting part of the peripheral blood test tube.

进一步地，所述限位部位于所述末梢血试管高度的1/5～4/5位置处。Further, the limiting part is located at 1/5-4/5 of the height of the peripheral blood test tube.

进一步地，还包括驱动所述振动板的偏心振动电机。Further, an eccentric vibration motor driving the vibration plate is also included.

进一步地，所述末梢血混匀组件还包括底板，所述振动板与所述底板弹性连接，所述限位板与所述底板固定连接。Further, the peripheral blood mixing assembly further includes a base plate, the vibrating plate is elastically connected to the base plate, and the limiting plate is fixedly connected to the base plate.

进一步地，所述底板设置于一滑块上，所述全自动进样样本分析仪内设置有与所述滑块相配合的滑轨。Further, the base plate is arranged on a slider, and a slide rail matched with the slider is arranged in the automatic sample analyzer.

进一步地，所述滑块与丝杆电机、步进电机或者气缸传动连接。Further, the slider is connected with a screw motor, a stepping motor or a cylinder in transmission.

进一步地，所述进样组件设置于所述全自动进样样本分析仪的外壳之外，所述采样组件、反应组件、检测组件、混匀装置设置于所述全自动进样样本分析仪的外壳内，所述采样组件位于所述反应组件上方，所述静脉血混匀组件和末梢血混匀组件位于所述反应组件的前方。Further, the sample injection component is arranged outside the shell of the automatic sampling sample analyzer, and the sampling component, reaction component, detection component, and mixing device are arranged on the outer shell of the automatic sample injection sample analyzer. In the casing, the sampling component is located above the reaction component, and the venous blood mixing component and peripheral blood mixing component are located in front of the reaction component.

本发明还提供一种全自动进样样样本分析仪，包括自动进样组件、混匀装置以及采样组件，所述混匀装置包括静脉血混匀组件和末梢血混匀组件，所述静脉血混匀组件包括抓手，所述抓手上下移动以抓取所述自动进样组件运送的试管，所述末梢血混匀组件沿一混匀路径横向移动，所述混匀路径与所述抓手上下移动的路径相交以使得所述末梢血混匀组件能够移动至所述抓手的正下方。The present invention also provides a fully automatic sampling sample analyzer, including an automatic sampling component, a mixing device and a sampling component, the mixing device includes a venous blood mixing component and a peripheral blood mixing component, the venous blood The mixing assembly includes a gripper, the gripper moves up and down to grab the test tube delivered by the automatic sampling assembly, the peripheral blood mixing assembly moves laterally along a mixing path, and the mixing path is connected to the gripper The paths that the hands move up and down intersect so that the peripheral blood mixing assembly can move directly under the gripper.

进一步地，所述末梢血混匀组件沿所述混匀路径在初始位、接收位和混匀位之间移动，在所述接收位，所述末梢血混匀组件位于所述抓手的正下方，待混匀的末梢血试管被放置于所述末梢血混匀组件或者混匀后的末梢血试管从所述末梢血混匀组件被移走；在所述混匀位，放置于所述末梢血混匀组件上的末梢血试管振动以将末梢血被混匀。Further, the peripheral blood mixing component moves along the mixing path between an initial position, a receiving position and a mixing position, and at the receiving position, the peripheral blood mixing component is located at the front of the handle. Below, the peripheral blood test tube to be mixed is placed in the peripheral blood mixing component or the mixed peripheral blood test tube is removed from the peripheral blood mixing component; at the mixing position, placed in the The peripheral blood test tube on the peripheral blood mixing component vibrates to mix the peripheral blood evenly.

进一步地，还包括反应组件，所述自动进样组件、混匀装置、反应组件沿前后方向顺序布置，所述采样组件位于所述反应组件上方，在所述初始位，所述末梢血混匀组件和所述反应组件在左右方向上错开。Further, it also includes a reaction component, the automatic sampling component, the mixing device, and the reaction component are sequentially arranged along the front and rear directions, the sampling component is located above the reaction component, and in the initial position, the peripheral blood is mixed Components and the reactive components are staggered left and right.

进一步地，所述末梢血混匀组件包括振动板和设置于所述振动板上方的限位板，所述振动板与一振动电机传动连接，所述振动板上形成混匀座以承接末梢血试管，所述限位板包括套接所述末梢血试管的限位部，所述限位部位于所述末梢血试管高度的1/5～4/5位置处。Further, the peripheral blood mixing assembly includes a vibrating plate and a limiting plate arranged above the vibrating plate, the vibrating plate is connected to a vibrating motor in transmission, and a mixing seat is formed on the vibrating plate to receive the peripheral blood For the test tube, the limiting plate includes a limiting part socketed on the peripheral blood test tube, and the limiting part is located at a position of 1/5 to 4/5 of the height of the peripheral blood test tube.

相较于现有技术，本发明全自动进样血液分析仪实现了更为简便的末梢血全血检测操作模式，一是无需稀释液的机外预稀释、二是对测量样本无严格定量要求影响，只需满足最小测试用量要求即可，如同静脉血的测量方式，通过本发明可以实现末梢血试样和静脉血试样在同一台机器上自动进样完成检测，本发明自动化程度高，释放了临床人员的劳动强度，提高了血液样本进样和检测的效率。Compared with the prior art, the automatic sample-injecting blood analyzer of the present invention realizes a more convenient operation mode of peripheral blood whole blood detection, one is that no pre-dilution of diluent is required outside the machine, and the other is that there is no strict quantitative requirement for the measurement sample It only needs to meet the minimum test dosage requirements, just like the measurement method of venous blood, through the present invention, the automatic sampling of the peripheral blood sample and the venous blood sample can be realized on the same machine to complete the detection. The present invention has a high degree of automation, The labor intensity of clinical personnel is released, and the efficiency of blood sample injection and detection is improved.

附图说明Description of drawings

图1为本发明全自动进样样本分析仪一实施例的结构示意图。Fig. 1 is a schematic structural view of an embodiment of a fully automatic sampling analyzer of the present invention.

图2为图1所示全自动进样样本分析仪的爆炸图。Fig. 2 is an exploded view of the fully automatic sampling analyzer shown in Fig. 1 .

图3为图2的另一角度视图。FIG. 3 is another perspective view of FIG. 2 .

图4为图1所示全自动进样样本分析仪的机架的结构示意图。FIG. 4 is a schematic structural view of the rack of the fully automatic sampling analyzer shown in FIG. 1 .

图5为图4所示机架的左侧视图。Fig. 5 is a left side view of the rack shown in Fig. 4 .

图6为图4所示机架的右侧视图。FIG. 6 is a right side view of the rack shown in FIG. 4 .

图7为图1所示全自动进样样本分析仪的末梢血混匀组件的结构示意图。FIG. 7 is a schematic structural diagram of the peripheral blood mixing component of the fully automatic sampling analyzer shown in FIG. 1 .

图8为图7的另一角度视图。FIG. 8 is another perspective view of FIG. 7 .

具体实施方式detailed description

为了便于理解本发明，下面将参照相关附图对本发明进行更全面的描述。附图中示例性地给出了本发明的一个或多个实施例，以使得本发明所公开的技术方案的理解更为准确、透彻。但是，应当理解的是，本发明可以以多种不同的形式来实现，并不限于以下所描述的实施例。In order to facilitate the understanding of the present invention, the present invention will be described more fully below with reference to the associated drawings. One or more embodiments of the present invention are exemplarily shown in the drawings, so as to make the understanding of the technical solutions disclosed in the present invention more accurate and thorough. However, it should be understood that the present invention can be implemented in various forms and is not limited to the embodiments described below.

本发明附图中相同或相似的标号对应相同或相似的部件；在本发明的描述中，需要理解的是，若有术语“上”、“下”、“左”、“右”等指示的方位或位置关系为基于附图所示的方位或位置关系，仅是为了便于描述本发明和简化描述，而不是指示或暗示所指的装置或元件必须具有特定的方位、以特定的方位构造和操作，因此附图中描述位置关系的用语仅用于示例性说明，不能理解为对本专利的限制，对于本领域的普通技术人员而言，可以根据具体情况理解上述术语的具体含义。In the drawings of the present invention, the same or similar symbols correspond to the same or similar components; The orientation or positional relationship is based on the orientation or positional relationship shown in the drawings, and is only for the convenience of describing the present invention and simplifying the description, rather than indicating or implying that the referred device or element must have a specific orientation, be configured in a specific orientation, and Therefore, the terms describing the positional relationship in the drawings are only for illustrative purposes, and should not be construed as limitations on this patent. Those of ordinary skill in the art can understand the specific meanings of the above terms according to specific situations.

本发明提供一种全自动进样样本分析仪，用于生物样本，特别是血液样本的检测分析。图1-3所示为本发明全自动进样样本分析仪的一具体实施例，包括外壳10、设置于外壳10内的机架20以及安装于机架20上的多个组件，包括转运组件30、采样组件31、反应组件32、检测组件33、电源组件35以及控制组件等。The invention provides a fully automatic sampling analyzer for the detection and analysis of biological samples, especially blood samples. Fig. 1-3 shows a specific embodiment of the automatic sampling sample analyzer of the present invention, including ahousing 10, aframe 20 arranged in thehousing 10, and a plurality of components installed on theframe 20, including atransport assembly 30.Sampling component 31,reaction component 32,detection component 33,power supply component 35, control component, etc.

外壳10包括后壳体12以及罩盖至后壳体12的前侧的前壳体14，前壳体14在其偏上的位置处铰接有面壳16，面壳16可以相对前壳体14旋转开合，方便操作人员添加或者更换检测所需的试剂等。较佳地，面壳16上嵌设有显示面板18，如触控面板等，操作人员可以通过显示面板18下达检测指令、设置检测参数、查看检测结果等。显示面板18与一主机通过有线或者无线的方式连接以传输并存储检测的相关数据。图示实施例中，前壳体14的底部高于后壳体12的底部，前壳体14底部偏右侧位置形成进样口，盛装有血液样本的试管50通过进样口进入外壳10并在外壳10内部完成整个检测过程。Theshell 10 includes arear shell 12 and afront shell 14 covering the front side of therear shell 12. Thefront shell 14 is hinged with aface shell 16 at its upper position, and theface shell 16 can be opposite to thefront shell 14. Rotate to open and close, convenient for the operator to add or replace the reagents required for detection, etc. Preferably, adisplay panel 18 is embedded on thecover 16, such as a touch panel, and the operator can issue detection instructions, set detection parameters, view detection results, etc. through thedisplay panel 18 . Thedisplay panel 18 is connected with a host through wired or wireless means to transmit and store detected relevant data. In the illustrated embodiment, the bottom of thefront housing 14 is higher than the bottom of therear housing 12, and the bottom of thefront housing 14 forms a sampling port on the right side, and thetest tube 50 containing the blood sample enters thehousing 10 through the sampling port and The entire detection process is completed inside thehousing 10 .

本发明全自动进样样本分析仪还包括一自动进样组件36，用于将盛装有待测血液样本的试管50运送至全自动进样样本分析仪的进样口。通常，盛装有不同人员的血液样本的多个试管50置放于同一试管架52上，自动进样组件36带动整个试管架52沿一自动进样路径移动，自动进样路径沿全自动进样样本分析仪的左右方向(即图示的X方向)延伸。图示实施例中，试管架52由左向右移动至对准全自动进样样本分析仪的进样口。使用时，后壳体12放置于一底座54上，底座54向前伸出横梁56以承载自动进样组件36。应当理解地，根据外壳10内各个组件的位置排布，进样口可以偏向前壳体14的左侧端设置或者设置于前壳体14的大致中间位置，相对应地自动进样组件36可以沿着自动进样路径自右向左移动至进样口。The automatic sampling analyzer of the present invention also includes anautomatic sampling component 36 for transporting thetest tube 50 containing the blood sample to be tested to the sample inlet of the automatic sampling analyzer. Usually, a plurality oftest tubes 50 filled with blood samples from different personnel are placed on the sametest tube rack 52, and theautomatic sampling assembly 36 drives the entiretest tube rack 52 to move along an automatic sampling path, and the automatic sampling path is along the path of automatic sampling. The left-right direction (that is, the X direction shown in the figure) of the sample analyzer extends. In the illustrated embodiment, thetest tube rack 52 moves from left to right to align with the sample inlet of the automatic sample analyzer. In use, therear casing 12 is placed on abase 54 , and the base 54 protrudes forward from thebeam 56 to carry theautomatic sampling assembly 36 . It should be understood that, according to the arrangement of the various components in thehousing 10, the sample inlet can be arranged at the left end of thefront housing 14 or roughly in the middle of thefront housing 14, and correspondingly, the automaticsample injection component 36 can be Move from right to left along the autosampling path to the injection port.

请同时参阅图4-6，机架20包括底板21、第一前侧板22、第二前侧板23、后侧板24以及连接各个侧板的连接柱。底板21水平设置，第一前侧板22、第二前侧板23以及后侧板24竖直设置。其中，后侧板24的底端连接至底板21的后侧端，第二前侧板23的底端连接至底板21的前侧端，第二前侧板23的顶端低于后侧板24的顶端。第一前侧板22位于第二前侧板23的前侧并与之相间隔，第一前侧板22的顶端与后侧板24的顶端相平齐并通过连接柱相连，第一前侧板22的底端高于底板21。后壳体12包覆机架20的左右两侧、上侧以及后侧，前壳体14罩盖第一前侧板22并与之相间隔。Please refer to FIGS. 4-6 at the same time. Theframe 20 includes abottom plate 21 , a firstfront side plate 22 , a secondfront side plate 23 , arear side plate 24 and connecting columns connecting each side plate. Thebottom board 21 is arranged horizontally, and the firstfront side board 22 , the secondfront side board 23 and therear side board 24 are arranged vertically. Wherein, the bottom end of therear side plate 24 is connected to the rear side end of thebase plate 21, the bottom end of the secondfront side plate 23 is connected to the front side end of thebase plate 21, and the top of the secondfront side plate 23 is lower than therear side plate 24 top of the . The firstfront side plate 22 is positioned at the front side of the secondfront side plate 23 and spaced therefrom, and the top end of the firstfront side plate 22 is flush with the top end of therear side plate 24 and is connected by a connecting column. The bottom end of theplate 22 is higher than thebottom plate 21 . Therear shell 12 covers the left and right sides, the upper side and the rear side of theframe 20 , and thefront shell 14 covers and is spaced from the firstfront side plate 22 .

机架20还包括横向的第一隔板25和第二隔板26，第一隔板25连接于第一前侧板22和后侧板24之间并架设于第二前侧板23的顶端之上。第一隔板25、第一前侧板22以及后侧板24在第一隔板25的上方界定出第一空间60，用于安装控制组件。第二隔板26连接于第二前侧板23和后侧板24之间，在竖直方向上相对地靠近底板21而远离第一隔板25。第二隔板26、底板21、第二前侧板23和后侧板24在第二隔板26的下方界定出第二空间62，用于安装电源组件35对整个全自动进样样本分析仪供电。图示中，第一前侧板22在对应面壳16或者说第一空间60的位置上设置有调压阀90、染液组件92等，其中调压阀90用于调整流路中的压力大小，染液组件92用于盛装染色试剂，操作人员打开面壳16即可操作调压阀90调节压力或者向染液组件92添加染色剂等。Theframe 20 also includes a transversefirst partition board 25 and asecond partition board 26, thefirst partition board 25 is connected between the firstfront side board 22 and therear side board 24 and erected on the top of the secondfront side board 23 above. Thefirst partition 25 , the firstfront side panel 22 and therear side panel 24 define afirst space 60 above thefirst partition 25 for installing the control components. Thesecond partition board 26 is connected between the secondfront side board 23 and therear side board 24 , relatively close to thebottom board 21 and away from thefirst partition board 25 in the vertical direction. Thesecond dividing plate 26, thebottom plate 21, the secondfront side plate 23 and therear side plate 24 define asecond space 62 below thesecond dividing plate 26, which is used to install thepower supply assembly 35 to the entire automatic sampling sample analyzer. powered by. In the illustration, the firstfront side plate 22 is provided with apressure regulating valve 90, adye solution assembly 92, etc. at the position corresponding to theface shell 16 or thefirst space 60, wherein thepressure regulating valve 90 is used to adjust the pressure in the flow path Size, thedye solution assembly 92 is used to hold dyeing reagents, and the operator can operate thepressure regulating valve 90 to adjust the pressure or add dyes to thedye solution assembly 92 by opening theface shell 16 .

机架20还包括竖直设置的第三隔板27，第三隔板27垂直于底板21和后侧板24，在上下方向(即图示的Z方向)上第三隔板27位于第一隔板25和底板21之间，在前后方向(即图示的Y方向)上第三隔板27连接于第二前侧板23和后侧板24之间。图示中，第二隔板26的宽度小于底板21的宽度并靠近机架20的右侧设置；第三隔板27位于第二隔板26的左侧并将第二空间62与第二隔板26左侧的空间隔开。第三隔板27、第一隔板25、底板21、第二前侧板23和底板21界定出第三空间64；第三隔板27、第一隔板25、第二隔板26、第二前侧板23和底板21界定出第四空间66。较佳地，第二隔板26的高度与第一前侧板22的底端的高度相当，第一空间60、第二空间62、第四空间66的尺寸均小于第三空间64的尺寸。Theframe 20 also includes athird partition 27 vertically arranged, thethird partition 27 is perpendicular to thebase plate 21 and therear side plate 24, and thethird partition 27 is located in the first vertical direction (ie the Z direction shown in the figure). Between thepartition board 25 and thebottom board 21 , thethird partition board 27 is connected between the secondfront side board 23 and therear side board 24 in the front-rear direction (that is, the illustrated Y direction). In the illustration, the width of thesecond partition 26 is less than the width of thebase plate 21 and is arranged near the right side of theframe 20; thethird partition 27 is positioned at the left side of thesecond partition 26 and separates thesecond space 62 from the second partition. The space on the left side of theplate 26 separates it. Thethird dividing plate 27, thefirst dividing plate 25, thebottom plate 21, the secondfront side plate 23 and thebottom plate 21 define thethird space 64; thethird dividing plate 27, thefirst dividing plate 25, thesecond dividing plate 26, the second dividing plate The twofront side panels 23 and thebottom panel 21 define afourth space 66 . Preferably, the height of thesecond partition 26 is equivalent to the height of the bottom of the firstfront side plate 22 , and the dimensions of thefirst space 60 , thesecond space 62 and thefourth space 66 are all smaller than the size of thethird space 64 .

第三隔板27左侧的转接板上穿设有多个阀门70(包括气阀和液阀)，用于控制全自动进样样本分析仪的各个流路(包括气路和液路)的通断，相应地第三空间64用于设置本发明全自动进样样本分析仪的流路(包括气路和液路)相关元件。第三隔板27右侧的转接板设有电线接口72，用于连接各种电线，包括电源线、控制线、信号线等。检测组件33包括普通阻抗检测装置、鞘流阻抗检测装置、光学流动室检测装置等，其中，涉及到流体的装置，包括普通阻抗检测装置、鞘流阻抗检测装置等设置于第四空间66；涉及到光电的装置，如光学流动室检测装置等，设置于第一空间60。通过第三隔板27的设置，将流路与电路隔开，实现电气分离，有效避免漏液对电路的损害和影响。第三空间64相对于第一、第二、第四空间60、62、66体积更大，方便了流路相关元件的安装，整体布局更为紧凑合理。A plurality of valves 70 (including gas valves and liquid valves) are perforated on the adapter plate on the left side of thethird partition 27, for controlling each flow path (including gas path and liquid path) of the automatic sampling sample analyzer Correspondingly, thethird space 64 is used to set the relevant components of the flow path (including gas path and liquid path) of the fully automatic sampling analyzer of the present invention. The adapter plate on the right side of thethird partition 27 is provided with awire interface 72 for connecting various wires, including power wires, control wires, signal wires and the like. Thedetection component 33 includes a common impedance detection device, a sheath flow impedance detection device, an optical flow chamber detection device, etc., wherein the devices related to fluid, including a common impedance detection device, a sheath flow impedance detection device, etc., are arranged in thefourth space 66; Devices to optoelectronics, such as optical flow cell detection devices, etc., are arranged in thefirst space 60 . Through the arrangement of thethird partition 27, the flow path and the circuit are separated, electrical separation is realized, and damage and influence on the circuit by liquid leakage are effectively avoided. Compared with the first, second andfourth spaces 60 , 62 and 66 , thethird space 64 is larger in volume, which facilitates the installation of components related to the flow path, and the overall layout is more compact and reasonable.

图示实施例中，控制组件包括主控板42、驱动板44、温控板46、刷卡板48等，其中，主控板40控制整个全自动进样样本分析仪的工作流程并处理检测信息以形成分析结果；驱动板44用于全自动进样样本分析仪中各流路的驱动控制；温控板46用于检测过程中的温度控制；刷卡板48用于识别操作人员的身份和权限，控制面壳16的开合，避免面壳16被随意打开而影响检测结果的准确性。控制组件位于顶部的第一空间60内、与底部的第二空间62内的电源组件35分别处于第四空间66的上下两侧，方便了电气连接，同时也使得整个全自动进样样本分析仪的重心偏下，稳定不易倒。In the illustrated embodiment, the control assembly includes amain control board 42, adrive board 44, atemperature control board 46, acard swiping board 48, etc., wherein the main control board 40 controls the workflow of the entire automatic sampling sample analyzer and processes detection information to form analysis results; the drivingboard 44 is used for the driving control of each flow path in the fully automatic sampling sample analyzer; thetemperature control board 46 is used for temperature control during the detection process; the swipingcard board 48 is used to identify the identity and authority of the operator , to control the opening and closing of theface shell 16, so as to prevent theface shell 16 from being opened arbitrarily and affect the accuracy of the detection result. The control assembly is located in thefirst space 60 at the top, and thepower supply assembly 35 in thesecond space 62 at the bottom is respectively located on the upper and lower sides of thefourth space 66, which facilitates the electrical connection and also makes the entire automatic sample analyzer The center of gravity is lower, stable and not easy to fall.

本发明全自动进样样本分析仪还包括混匀装置，混匀装置包括静脉血混匀组件37和末梢血混匀组件38。静脉血混匀组件37包括抓手371和驱动抓手上下移动的气缸373，抓手371从试管架52上抓取盛装有血液样本的试管50。较佳地，抓手371与控制组件连接，根据所抓取的试管50的种类变化抓手371的后续操作。当抓手371所抓取的试管50为静脉血试管时，抓手371带动所抓取的静脉血试管在X-Z平面上旋转混匀或者叫颠倒混匀，混匀后的静脉血试管由转运组件30运送至采样位；当抓手371所抓取的试管50为末梢血试管时，抓手371将所抓取的末梢血试管放置于末梢血混匀组件38进行混匀，混匀后的末梢血试管被抓手371抓离末梢血混匀组件38，之后由转运组件30运送至采样位。The automatic sampling sample analyzer of the present invention also includes a mixing device, which includes a venousblood mixing component 37 and a peripheralblood mixing component 38 . The venousblood mixing assembly 37 includes ahandle 371 and anair cylinder 373 that drives the handle to move up and down. Thehandle 371 grabs thetest tube 50 containing the blood sample from thetest tube rack 52 . Preferably, thegripper 371 is connected with the control assembly, and the subsequent operation of thegripper 371 can be changed according to the type of thetest tube 50 to be gripped. When thetest tube 50 grasped by thegripper 371 is a venous blood test tube, thegripper 371 drives the grasped venous blood test tube on the X-Z plane to rotate or mix evenly, and the mixed venous blood test tube is transported by thetransport assembly 30 is transported to the sampling position; when thetest tube 50 grasped by thegripper 371 is a peripheral blood test tube, thegripper 371 places the grasped peripheral blood test tube in the peripheralblood mixing component 38 for mixing, and the mixed peripheral blood The blood test tube is grasped by thegripper 371 from the peripheralblood mixing component 38, and then transported to the sampling position by thetransfer component 30.

请同时参阅图7和图8，末梢血混匀组件38包括振动板381和设置于振动板381上方的限位板383。振动板381上形成混匀座382，用于承接待混匀的末梢血试管50。振动板381可由一偏心电机驱动，偏心振动的动力从末梢血试管50的底部向上传递，使末梢血试管50高频振动进而使其承载的末梢血能够呈旋涡式混匀。限位板383与振动板381之间的间隔小于末梢血试管50的高度，限位板383在对应混匀座382的位置上形成有穿孔384，通过穿孔384将限位板383套接在末梢血试管50上。较佳地，限位板383处于末梢血试管50的高度的1/5～4/5位置处，对末梢血试管50形成限制，避免其在振动板381高频振动的作用下跳出混匀座382。Please refer to FIG. 7 and FIG. 8 at the same time, the peripheralblood mixing assembly 38 includes a vibratingplate 381 and a limitingplate 383 arranged above the vibratingplate 381 . A mixingseat 382 is formed on the vibratingplate 381 for receiving the peripheralblood test tube 50 to be mixed. The vibratingplate 381 can be driven by an eccentric motor, and the power of eccentric vibration is transmitted upwards from the bottom of the peripheralblood test tube 50, so that the peripheralblood test tube 50 vibrates at high frequency and the peripheral blood carried by it can be mixed in a vortex manner. The distance between the limitingplate 383 and the vibratingplate 381 is smaller than the height of the peripheralblood test tube 50, the limitingplate 383 is formed with aperforation 384 at the position corresponding to the mixingseat 382, and the limitingplate 383 is sleeved on the distal end through theperforation 384Blood test tube 50 on. Preferably, the limitingplate 383 is located at the position of 1/5 to 4/5 of the height of the peripheralblood test tube 50, forming a limit on the peripheralblood test tube 50, preventing it from jumping out of the mixing seat under the action of the high-frequency vibration of the vibratingplate 381 382.

较佳地，末梢血混匀组件38包括一混匀路径，末梢血混匀组件38沿混匀路径在初始位A、混匀位B和接收位C之间移动。末梢血混匀组件38移动至接收位C时，其混匀座382位于抓手371的正下方，抓手371张开将从自动进样组件36上抓取的末梢血试管50下放至混匀座382内；之后，末梢血混匀组件38移动至混匀位B，振动板381开始高频振动并使得末梢血试管50内的末梢血样本呈旋涡式混匀；末梢血混匀之后，末梢血混匀组件38再次移动至接收位C，抓手371将混匀后的末梢血试管50从混匀座382取走。所有末梢血试管50在完成混匀后，末梢血混匀组件38回到初始位A。在一些实施例中，初始位A和混匀位B可以是同一位置。Preferably, the peripheralblood mixing component 38 includes a mixing path, and the peripheralblood mixing component 38 moves between the initial position A, the mixing position B and the receiving position C along the mixing path. When the peripheralblood mixing assembly 38 moves to the receiving position C, its mixingseat 382 is located directly below thegripper 371, and thegripper 371 is opened to lower the peripheralblood test tube 50 grasped from theautomatic sampling assembly 36 to the mixing chamber. After that, the peripheralblood mixing assembly 38 moves to the mixing position B, and the vibratingplate 381 starts to vibrate at a high frequency and makes the peripheral blood sample in the peripheralblood test tube 50 vortex mixed; after the peripheral blood is mixed, the peripheral blood Theblood mixing component 38 moves to the receiving position C again, and thegripper 371 takes the mixed peripheralblood test tube 50 away from the mixingseat 382 . After all the peripheralblood test tubes 50 are completely mixed, the peripheralblood mixing component 38 returns to the initial position A. In some embodiments, the initial position A and the mixing position B may be the same position.

图示实施例中，振动板381通过弹性件，如弹簧等连接至一底板384上，限位板383固定连接于底板384上，使得振动板381在振动电机的作用下可以高频振动。较佳地，底板384的底部连接有滑块385，机架20上设置有与滑块385相配合的滑轨29，丝杆电机28驱动滑块385并带动混匀座382沿混匀路径移动。当然，滑块385也可以由步进电机、气缸等驱动。较佳地，混匀路径沿X方向延伸并与抓手371的移动路径垂直相交，使得末梢血混匀组件38在接收位C时，其混匀座382正对抓手371。在上下方向上，混匀座382所处的位置高于自动进样组件36，优选地高于自动进样组件36上的试管50，方便本发明全自动进样样本分析仪进样。较佳地，末梢血混匀组件38上设置有感应片387，感应片387与光耦作用，检测末梢血混匀组件38，特别是混匀座382的位置并根据混匀座382的位置控制末梢血混匀组件38沿混匀路径的移动。In the illustrated embodiment, the vibratingplate 381 is connected to abase plate 384 through elastic members, such as springs, and the limitingplate 383 is fixedly connected to thebase plate 384, so that the vibratingplate 381 can vibrate at high frequency under the action of the vibrating motor. Preferably, the bottom of thebottom plate 384 is connected with aslider 385, and theframe 20 is provided with aslide rail 29 matched with theslider 385, and thescrew motor 28 drives theslider 385 and drives the mixingseat 382 to move along the mixing path . Of course, theslider 385 can also be driven by a stepping motor, an air cylinder, or the like. Preferably, the mixing path extends along the X direction and perpendicularly intersects with the moving path of thehandle 371 , so that when the peripheralblood mixing assembly 38 is at the receiving position C, its mixingseat 382 faces thehandle 371 . In the vertical direction, the position of the mixingseat 382 is higher than theautomatic sampling assembly 36, preferably higher than thetest tube 50 on theautomatic sampling assembly 36, which is convenient for the automatic sampling sample analyzer of the present invention to introduce samples. Preferably, the peripheralblood mixing component 38 is provided with aninduction piece 387, and theinduction piece 387 acts with an optocoupler to detect the position of the peripheralblood mixing component 38, especially the mixingseat 382, and control the position according to the position of the mixingseat 382. The movement of the peripheralblood mixing component 38 along the mixing path.

图示实施例中，混匀组件37、38设置于第一前侧板22与前壳体14之间的空间内，第一前侧板22与第二前侧板23之间的空间设置采样组件31和反应组件32。反应组件32包括多个反应池，如WBC/RBC池、WDF/RET池等。各个反应池沿X方向排布，采样组件31的采样轨道位于各个反应池的正上方。在前后方向上，混匀组件37、38位于反应组件32的前侧，转运组件30将混匀后的试管50沿Y方向由前向后移动至采样组件31下方。较佳地，在初始位A时，末梢血混匀组件38偏置于反应组件32的一侧，如图示的右侧，从而在左右方向上末梢血混匀组件38与反应组件32错开，可以方便用户清洗和维护反应组件32。在其它实施例中，末梢血混匀组件38的混匀路径也可以沿Y方形设置并与反应组件32在左右方向上错开。In the illustrated embodiment, the mixingcomponents 37, 38 are arranged in the space between the firstfront side plate 22 and thefront housing 14, and the space between the firstfront side plate 22 and the secondfront side plate 23 is provided withsampling Component 31 and ReactComponent 32. Thereaction component 32 includes multiple reaction pools, such as WBC/RBC pools, WDF/RET pools, and the like. Each reaction pool is arranged along the X direction, and the sampling track of thesampling component 31 is located directly above each reaction pool. In the front-to-back direction, the mixingcomponents 37 and 38 are located at the front side of thereaction component 32 , and thetransfer component 30 moves themixed test tube 50 from front to back to the bottom of thesampling component 31 along the Y direction. Preferably, in the initial position A, the peripheralblood mixing component 38 is biased to one side of thereaction component 32, such as the right side in the figure, so that the peripheralblood mixing component 38 and thereaction component 32 are staggered in the left and right direction, It is convenient for users to clean and maintain thereaction component 32 . In other embodiments, the mixing path of the peripheralblood mixing component 38 may also be arranged along a Y shape and staggered with thereaction component 32 in the left-right direction.

转运组件30包括一转运路径，转运路径与抓手371的移动路径垂直相交。图示实施例中，转运组件30设置于第二隔板26上，其前端穿过第二前侧板23而向前伸出，确保转运组件30能够承接混匀后的试管50。较佳地，转运组件30上设置有常规试管座和适配座，常规试管座用于放置静脉血试管、适配座用于放置并适配不同类型的末梢血试管，适配座的高度低于常规试管座。较佳地，本发明全自动进样样本分析仪还包括锁紧组件39，锁紧组件39将转运组件30的常规试管座/适配座上的试管50夹紧固定使其保持在竖直状态，方便采样针穿刺采用。较佳地，第一前侧板22在对应第二前侧板23的位置上开口，方便反应组件32、锁紧组件39等设置，也方便试管50、转运组件30等的移动。Thetransfer assembly 30 includes a transfer path perpendicular to the movement path of thehandle 371 . In the illustrated embodiment, thetransfer assembly 30 is disposed on thesecond partition 26 , and its front end protrudes forward through the secondfront side plate 23 to ensure that thetransfer assembly 30 can receive themixed test tube 50 . Preferably, thetransfer assembly 30 is provided with a conventional test tube seat and an adapter seat, the conventional test tube seat is used to place venous blood test tubes, and the adapter seat is used to place and adapt different types of peripheral blood test tubes, the height of the adapter seat is low in conventional test tube holders. Preferably, the automatic sampling sample analyzer of the present invention also includes a lockingassembly 39, and the lockingassembly 39 clamps and fixes thetest tube 50 on the conventional test tube holder/adapter seat of thetransfer assembly 30 to keep it in a vertical state , to facilitate the adoption of sampling needle puncture. Preferably, the firstfront side plate 22 is opened at a position corresponding to the secondfront side plate 23, which facilitates the installation of thereaction component 32, the lockingcomponent 39, and the movement of thetest tube 50, thetransfer component 30, and the like.

采样组件31沿一分样路径在采样位和多个样本分配位之间移动。分样路径设置于转运路径上方并与转运路径呈角度设置，图示实施例中，分样路径沿X方向延伸，与Y方向的转运路径相垂直，可以确保采样针沿X方向的移动能与下方的试管50相对齐。如此，在采样位，采样针准确地穿刺采样，防止对位不准而导致采样针损坏；之后，采样组件31沿分样路径移动至各样本分配位，采样针将所吸取的血液样本释放至反应组件32的各个反应池。反应池根据所要检测的内容配置有相应的检测试剂，血液样本在反应池中与检测试剂混匀后形成待测样本液，待测样本液通过检测组件33即得到相应的血液样本信息。Thesampling component 31 moves between a sampling bit and a plurality of sample allocation bits along a decimation path. The sample distribution path is set above the transfer path and is set at an angle with the transfer path. In the illustrated embodiment, the sample distribution path extends along the X direction and is perpendicular to the transfer path in the Y direction, which can ensure that the movement of the sampling needle along the X direction can be consistent with the Thelower test tubes 50 are aligned. In this way, at the sampling position, the sampling needle accurately punctures the sample to prevent the sampling needle from being damaged due to misalignment; after that, thesampling assembly 31 moves to each sample allocation position along the sample dividing path, and the sampling needle releases the drawn blood sample to Each reaction pool of thereaction assembly 32. The reaction pool is configured with corresponding detection reagents according to the content to be detected. The blood sample is mixed with the detection reagent in the reaction pool to form a sample liquid to be tested. The sample liquid to be tested passes through thedetection component 33 to obtain the corresponding blood sample information.

第三空间64的上部，即靠近第一隔板25的位置处设置有储液罐74和注射器76；第三空间64的下部，即靠近底板21的位置处设置有定量泵78和防气泡罐79。储液罐74存储有检测所需的各种试剂，可以是的特定蛋白检测试剂、荧光试剂、稀释液、鞘液等；注射器76提供动力使采样针吸取试管50内的血液样本并释放至各个反应池中；定量泵78将所需的各种试剂按预定量加入至相应的反应池内，检测试剂与血液样本在反应组件32内混合形成待测液。防气泡罐79设置于定量泵78的上方以防止气泡的产生，避免影响检测结果。较佳地，第三空间64内还设置有多个废液罐80，用于暂存检测过程所产生的废液。The upper part of thethird space 64, that is, aliquid storage tank 74 and asyringe 76 are arranged near the position of thefirst partition 25; 79. Theliquid storage tank 74 stores various reagents required for detection, which can be specific protein detection reagents, fluorescent reagents, diluents, sheath fluids, etc.; thesyringe 76 provides power to make the sampling needle suck the blood sample in thetest tube 50 and release it to each In the reaction pool: thequantitative pump 78 adds various required reagents into the corresponding reaction pool according to the predetermined amount, and the detection reagent and the blood sample are mixed in thereaction component 32 to form the liquid to be tested. Theanti-bubble tank 79 is arranged above thequantitative pump 78 to prevent the generation of bubbles and avoid affecting the detection results. Preferably, a plurality ofwaste liquid tanks 80 are also arranged in thethird space 64 for temporarily storing the waste liquid generated during the detection process.

本发明全自动进样样本分析仪用于样本检测时，其操作步骤包括：进样，进样组件沿X方向移动运送承载有待测样本的试管；混匀，抓手沿Z方向移动抓取进样的试管，若所抓取的试管为静脉血试管则抓手执行混匀操作；若所抓取的试管为末梢血试管则抓手将所抓取的试管放置于末梢血混匀组件执行混匀操作；转运，转运组件将混匀后的试管沿Y方向运送至采样位；采样，采样组件将在采样位采样并沿X方向移动将样本分注至反应组件；检测，检测试剂与样本相混合的待测液通过检测组件以获取检测结果。本发明中，采样组件在分析仪内部完成穿刺采样和样本的分配，整个过程不受外界环境的干扰，可以有效避免血液样本被环境污染、确保检测结果的准确定。When the automatic sampling sample analyzer of the present invention is used for sample detection, its operation steps include: sample feeding, the sample feeding component moves along the X direction to transport the test tube carrying the sample to be tested; mixing, and the gripper moves along the Z direction to grab For the sample-injected test tube, if the grasped test tube is a venous blood test tube, the grasper performs the mixing operation; if the grasped test tube is a peripheral blood test tube, the grasper places the grasped test tube in the peripheral blood mixing component for execution Mixing operation; transfer, the transfer component transports the mixed test tube to the sampling position along the Y direction; sampling, the sampling component will sample at the sampling position and move along the X direction to dispense the sample to the reaction component; detection, detection of reagents and samples The mixed liquids to be tested pass through the detection component to obtain the detection result. In the present invention, the sampling component completes puncture sampling and sample distribution inside the analyzer, and the whole process is not disturbed by the external environment, which can effectively prevent the blood sample from being polluted by the environment and ensure the accuracy of the test result.

另外，本发明中，采样组件和进样组件均沿X方向移动，试管在混匀后通过转运组件转运至采样组件，可以确保采样组件的采样针与试管对正，避免穿刺时由于未对准而损坏采样针，影响检测的进行；末梢血混匀组件沿X方向移动，与抓手的移动路径垂直相交，确保所抓取的末梢血试管能够准确地投放至混匀座内混匀，混匀时末梢血混匀组件移动至偏离抓手的位置以避免妨碍抓手的其它操作，末梢血混匀组件在初始位时偏离反应组件设置，方便各个反应池的清洗与维护；机架通过隔板分隔出多个空间，实现液电的分离，避免漏液影响电气安全，隔板两侧分别连接电路和流路，也使得流路与电路的设置和连接更为简单，整体布局紧凑合理。In addition, in the present invention, both the sampling assembly and the sampling assembly move along the X direction, and the test tube is transferred to the sampling assembly through the transfer assembly after mixing, which can ensure that the sampling needle of the sampling assembly is aligned with the test tube, and avoid misalignment during puncturing. Damage to the sampling needle will affect the detection; the peripheral blood mixing component moves along the X direction and intersects with the movement path of the gripper perpendicularly to ensure that the captured peripheral blood test tubes can be accurately put into the mixing seat for mixing. Evenly, the peripheral blood mixing component moves to a position away from the gripper to avoid hindering other operations of the gripper. The peripheral blood mixing component is set away from the reaction component at the initial position, which is convenient for cleaning and maintenance of each reaction pool; the rack passes through the partition The board separates multiple spaces to realize the separation of liquid and electricity, and avoid leakage affecting electrical safety. The two sides of the partition are respectively connected to the circuit and the flow path, which also makes the setting and connection of the flow path and the circuit easier, and the overall layout is compact and reasonable.

本发明全自动进样样本分析仪，实现了更为简便的末梢血全血检测操作模式，一是无需稀释液的机外预稀释、二是对测量样本无严格定量要求影响，只需满足最小测试用量要求即可，如同静脉血的测量方式，通过本发明可以实现末梢血试样和静脉血试样在同一台机器上自动进样完成检测，不需要分别在不同的对应血细胞分析仪上检测，简化了医护人员的操作，降低了医院检测的成本。同时本发明可以设置检测单元自动识别静脉血试管和末梢血试管的试管类型，并根据试管类型实施对应的血液混匀方式、控制采样针自动进行抽样分析，最后输出分析测量结果。本发明实施例提供的全自动进样样本分析仪自动化程度高，释放了临床人员的劳动强度，提高了血液样本进样和检测的效率。The automatic sampling analyzer of the present invention realizes a more convenient operation mode for peripheral blood whole blood detection. First, it does not require external pre-dilution of diluent, and second, it does not have strict quantitative requirements on the measurement samples. Just like the measurement method of venous blood, the present invention can realize the automatic injection of peripheral blood samples and venous blood samples on the same machine to complete the detection, without the need of testing on different corresponding blood cell analyzers , Simplify the operation of medical staff and reduce the cost of hospital testing. At the same time, the present invention can set the detection unit to automatically identify the test tube types of venous blood test tubes and peripheral blood test tubes, implement the corresponding blood mixing method according to the test tube types, control the sampling needle to automatically perform sampling analysis, and finally output the analysis and measurement results. The fully automatic sampling sample analyzer provided by the embodiment of the present invention has a high degree of automation, relieves the labor intensity of clinical personnel, and improves the efficiency of blood sample sampling and detection.

需要说明的是，本发明并不局限于上述实施方式，根据本发明的创造精神，本领域技术人员还可以做出其他变化，这些依据本发明的创造精神所做的变化，都应包含在本发明所要求保护的范围之内。It should be noted that the present invention is not limited to the above-mentioned embodiments, and those skilled in the art can make other changes according to the inventive spirit of the present invention, and these changes made according to the inventive spirit of the present invention should be included in this document. within the scope of the claimed invention.

Claims (19)

1. A full-automatic sample feeding sample analyzer comprises an automatic sample feeding assembly, a sampling assembly, a reaction assembly and a detection assembly, and is characterized by further comprising a blending device arranged between the automatic sample feeding assembly and the sampling assembly, wherein the blending device comprises a vein blood blending assembly and a peripheral blood blending assembly, the peripheral blood blending assembly moves to a receiving position or a blending position along a blending path, and in the receiving position, a peripheral blood test tube to be blended is placed in the peripheral blood blending assembly or the blended peripheral blood test tube is moved away from the peripheral blood blending assembly; and at the blending position, a peripheral blood test tube placed on the peripheral blood blending component vibrates to blend peripheral blood, the blended sample and the detection reagent are mixed in the reaction component to form sample liquid to be detected, and the sample liquid to be detected passes through the detection component to obtain a sample detection result.

2. The full-automatic sample feeding sample analyzer according to claim 1, wherein the mixing path is arranged along a left-right direction of the full-automatic sample feeding sample analyzer, the mixing path further comprises an initial position, and in the initial position, the peripheral blood mixing component and the reaction component are staggered in the left-right direction; or the blending path is arranged along the front and back direction of the full-automatic sample feeding sample analyzer, and the peripheral blood blending assembly and the reaction assembly are staggered in the left and right direction.

3. The full-automatic sample introduction sample analyzer according to claim 2, wherein the initial position and the mixing position are at the same position; or the initial position and the mixing position are two different positions.

4. The full autosampler sample analyzer of claim 1, wherein said autosampler assembly moves along a sample path to transport test tubes to said full autosampler sample analyzer, said sample path being parallel to and lower than said blending path; or the sample feeding path is perpendicular to the blending path and lower than the blending path.

5. The analyzer of claim 1, wherein the sampling assembly moves along a sample dividing path and divides the sample into the reaction assembly, and the sample dividing path is parallel to and higher than the mixing path; or the sample dividing path is perpendicular to the blending path and higher than the blending path.

6. The full autosampler sample analyzer of claim 5, further comprising a transfer assembly, the transfer assembly moving along a transfer path to transfer the test tube from the mixing device to the sampling assembly, the transfer path being perpendicular to and below the sample splitting path.

7. The full-automatic sample feeding sample analyzer according to claim 1, wherein the venous blood blending assembly comprises a gripper, the gripper moves up and down to grip the test tube conveyed by the automatic sample feeding assembly, and when the test tube gripped by the gripper is a venous blood test tube, the gripper rotates and blends or inverts the gripped venous blood test tube to blend; when the test tube grabbed by the hand grab is a peripheral blood test tube, the peripheral blood blending assembly moves to the receiving position to receive the peripheral blood test tube grabbed by the hand grab.

8. The full-automatic sample feeding sample analyzer of claim 7, wherein the peripheral blood blending component comprises an induction sheet, and the induction sheet is matched with the optical coupler to detect the position of the peripheral blood blending component.

9. The analyzer according to claim 7, wherein the tip blood mixing assembly comprises a vibrating plate and a limiting plate disposed above the vibrating plate, the vibrating plate is provided with a mixing seat for receiving the tip blood test tube, and the limiting plate comprises a limiting portion sleeved on the tip blood test tube.

10. The full autosampler sample analyzer of claim 9, wherein said stopper is located at 1/5-4/5 of the height of said peripheral blood test tube.

11. The full autosampler sample analyzer of claim 9, further comprising an eccentric vibrating motor driving said vibrating plate.

12. The analyzer for full-automatic sample introduction and sample analysis according to claim 9, wherein the peripheral blood blending assembly further comprises a bottom plate, the vibrating plate is elastically connected with the bottom plate, and the limiting plate is fixedly connected with the bottom plate.

13. The analyzer of claim 12, wherein the bottom plate is disposed on a slide block, and a slide rail is disposed in the analyzer and is engaged with the slide block.

14. The analyzer of claim 13, wherein the slide block is in driving connection with a lead screw motor, a stepper motor or a cylinder.

15. The full-automatic sample feeding sample analyzer according to any one of claims 1 to 14, wherein the sample feeding component is disposed outside a housing of the full-automatic sample feeding sample analyzer, the sampling component, the reaction component, the detection component and the mixing device are disposed in the housing of the full-automatic sample feeding sample analyzer, the sampling component is located above the reaction component, and the venous blood mixing component and the peripheral blood mixing component are located in front of the reaction component.

16. The utility model provides a full autoinjection sample analysis appearance, includes autoinjection subassembly, mixing device and sampling subassembly, a serial communication port, the mixing device includes venous blood mixing subassembly and tip blood mixing subassembly, venous blood mixing subassembly includes the tongs, the tongs reciprocates in order to snatch the test tube that the autoinjection subassembly transported, tip blood mixing subassembly is along a mixing route lateral shifting, the mixing route with the route that the tongs reciprocated intersects so that tip blood mixing subassembly can move extremely under the tongs.

17. The full-automatic sample introduction sample analyzer of claim 16, wherein the distal homogenizing assembly moves along the homogenizing path between an initial position, a receiving position, and a homogenizing position, wherein in the receiving position, the distal homogenizing assembly is positioned directly below the handle, and the distal blood test tube to be homogenized is placed on the distal homogenizing assembly or the homogenized distal blood test tube is removed from the distal homogenizing assembly; at the mixing position, the peripheral blood test tube placed on the peripheral blood mixing unit is vibrated to mix the peripheral blood.

18. The full-automatic sample introduction sample analyzer according to claim 17, further comprising a reaction assembly, wherein the automatic sample introduction assembly, the blending device, and the reaction assembly are sequentially arranged in a front-rear direction, the sampling assembly is located above the reaction assembly, and in the initial position, the peripheral blood blending assembly and the reaction assembly are staggered in a left-right direction.

19. The analyzer according to claim 16, wherein the peripheral blood mixing assembly comprises a vibrating plate and a position-limiting plate disposed above the vibrating plate, the vibrating plate is in transmission connection with a vibrating motor, a mixing seat is formed on the vibrating plate to receive the peripheral blood test tube, the position-limiting plate comprises a position-limiting portion sleeved on the peripheral blood test tube, and the position-limiting portion is located at a position of 1/5-4/5 of the height of the peripheral blood test tube.

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