CN115444766B - A kind of two-component shampoo with scalp nourishing effect and preparation method thereof - Google Patents

Abstract

The invention relates to a bi-component shampoo with scalp nourishing effect and a preparation method thereof, wherein the bi-component shampoo with scalp nourishing effect comprises a first component and a second component; the first component comprises a surfactant, a foam booster, a conditioner, a thickener, a lubricant, a preservative, a pH regulator and water; the second component comprises a humectant, a conditioning agent and water; the conditioning agent in the second component comprises a strontium containing compound. The invention creatively adds the strontium-containing compound into the shampoo product, utilizes the biological activities of strontium element such as promoting collagen formation, inducing angiogenesis, promoting cell endothelial proliferation and the like to keep scalp activity, nourish hair follicles, maintain the basic environment of hair growth, further grows stronger and healthy hair, and strontium enters the human body through the scalp to supplement microelements.

Description

Translated fromChinese

一种具有头皮滋养功效的双组分洗发水及其制备方法Two-component shampoo with scalp nourishing effect and preparation method thereof

技术领域Technical Field

本发明属于日化产品技术领域，具体涉及一种具有头皮滋养功效的双组分洗发水及其制备方法。The invention belongs to the technical field of daily chemical products, and particularly relates to a two-component shampoo with scalp nourishing effect and a preparation method thereof.

背景技术Background Art

一个人头发的状态往往可以反映出关于这个人的很多信息，譬如健康状态、精神面貌、心态、生活习惯等等，所以人们也越来越重视个人的头发护理。洗发水是人们日常生活中使用频率最高的头发洗护产品，主要起到清洁头皮与发丝的功能。目前市场上的洗发水，大多只有单一的清洁功能，对头发和头皮并没有养护作用，不能从根本上促进头皮和头发的健康。另一方面，为了追求更多的生发、防脱等功效，有的洗发产品添加了大量的胺性成分、表面活性剂，甚至添加了一些固态医药成分，这些添加剂大多难溶于水，从而到导致洗发水乳化体系不稳定，不但影响了洗发水的外观、使用手感，甚至使得其功能性难以充分发挥。The state of a person's hair can often reflect a lot of information about the person, such as health status, mental outlook, mentality, living habits, etc., so people are paying more and more attention to personal hair care. Shampoo is the most frequently used hair care product in people's daily life, and its main function is to clean the scalp and hair. Most of the shampoos on the market currently have only a single cleaning function, and have no maintenance effect on the hair and scalp, and cannot fundamentally promote the health of the scalp and hair. On the other hand, in order to pursue more hair growth, anti-hair loss and other effects, some shampoo products add a large amount of amine ingredients, surfactants, and even some solid pharmaceutical ingredients. Most of these additives are difficult to dissolve in water, which leads to the instability of the shampoo emulsification system, which not only affects the appearance and feel of the shampoo, but also makes it difficult to fully exert its functionality.

CN110496084A公开了一种修复头皮损伤清洁洗发露，该洗发露由以下质量百分比的原料制备：椰油酰谷氨酸钠5-10％、月桂基葡萄糖羧酸钠5-10％、椰油酰甘氨酸钠2-5％、椰油酰胺丙基甜菜碱5-10％、肉豆蔻基葡萄糖苷2-5％、月桂酰肌氨酸钠2-5％、无患子果提取液2-8％、穿心莲提取液1-5％、金银花提取液1-5％、黄莲提取液1-5％、甘油5-10％、去离子水余量。CN110496084A discloses a shampoo for repairing scalp damage and cleaning. The shampoo is prepared from the following raw materials in percentage by mass: 5-10% sodium cocoyl glutamate, 5-10% sodium lauryl glucose carboxylate, 2-5% sodium cocoyl glycinate, 5-10% cocamidopropyl betaine, 2-5% myristyl glucoside, 2-5% sodium lauroyl sarcosinate, 2-8% soapberry fruit extract, 1-5% andrographis paniculata extract, 1-5% honeysuckle extract, 1-5% coptis chinensis extract, 5-10% glycerol, and the balance deionized water.

CN109864913A公开了一种银杏叶洗发露及其制备方法。该洗发露包括硅油和银杏叶提取物，还包括侧柏叶提取物，生姜提取物，艾叶提取物，人参提取物中的一种或一种以上组分。采用超声波提取的银杏叶提取物，作为洗发露的活性成分，银杏叶提取物能清除头皮表面自由基，去头皮屑，滋养头皮细胞，并且能促进硅油在头发表面的沉积，使得清洗过的头发富有光泽，乌黑发亮。CN109864913A discloses a ginkgo leaf shampoo and a preparation method thereof. The shampoo comprises silicone oil and ginkgo leaf extract, and also comprises one or more components of orientalis leaf extract, ginger extract, wormwood leaf extract, and ginseng extract. The ginkgo leaf extract extracted by ultrasonic wave is used as the active ingredient of the shampoo. The ginkgo leaf extract can remove free radicals on the scalp surface, remove dandruff, nourish scalp cells, and promote the deposition of silicone oil on the hair surface, so that the washed hair is glossy and shiny.

现有技术中公开的洗发产品中的活性滋养成分为中药植物提取物、植物精油、蛋白质氨基酸等，但这些成分多为大分子物质，真正能被皮肤细胞吸收起到实际功效的并不多。The active nourishing ingredients in the shampoo products disclosed in the prior art include Chinese herbal plant extracts, plant essential oils, protein amino acids, etc., but most of these ingredients are macromolecular substances, and not many of them can be truly absorbed by skin cells to play a practical role.

因此，开发一种易被头皮吸收、成分安全、兼具头皮养护清洁与发丝养护清洁功效的洗发产品是非常有意义的。Therefore, it is very meaningful to develop a shampoo product that is easily absorbed by the scalp, has safe ingredients, and has both scalp care and hair care and cleansing effects.

发明内容Summary of the invention

针对现有技术的不足，本发明的目的在于提供一种具有头皮滋养功效的双组分洗发水及其制备方法。In view of the deficiencies of the prior art, the object of the present invention is to provide a two-component shampoo with scalp nourishing effect and a preparation method thereof.

为达到此发明目的，本发明采用以下技术方案：In order to achieve the purpose of the invention, the present invention adopts the following technical solutions:

第一方面，本发明提供一种具有头皮滋养功效的双组分洗发水，所述具有头皮滋养功效的双组分洗发水包括第一组分和第二组分；In a first aspect, the present invention provides a two-component shampoo with scalp nourishing effect, wherein the two-component shampoo with scalp nourishing effect comprises a first component and a second component;

所述第一组分包括表面活性剂、增泡剂、调理剂、增稠剂、润滑剂、防腐剂、pH调节剂和水；所述第二组分包括保湿剂、调理剂和水；The first component includes a surfactant, a foaming agent, a conditioning agent, a thickener, a lubricant, a preservative, a pH adjuster and water; the second component includes a moisturizer, a conditioning agent and water;

所述第二组分中的调理剂包括含锶化合物；所述含锶化合物包括氯化锶、六水合氯化锶、氢氧化锶、醋酸锶、柠檬酸锶、葡萄糖酸锶、PCA锶中的任意一种或至少两种的组合。The conditioning agent in the second component includes a strontium-containing compound; the strontium-containing compound includes any one of strontium chloride, strontium chloride hexahydrate, strontium hydroxide, strontium acetate, strontium citrate, strontium gluconate, and PCA strontium, or a combination of at least two thereof.

锶是人体与生俱来的一种维持生命体生长不可或缺的微量元素，锶在人体中发挥着多种生物活性，锶离子粒径微小，较有机大分子来说更容易渗透进皮肤及发丝当中，本发明创造性地将含锶化合物添加入洗发产品中，利用锶元素促进胶原蛋白形成、诱导血管生成、促进细胞内皮增殖等生物活性来保持头皮活力、滋养毛囊，维护头发生长的基础环境，进而生长出更加强韧、健康的发丝，锶通过头皮进入人体还起到了补充微量元素的作用。Strontium is a trace element that is innate to the human body and is indispensable for maintaining the growth of life. Strontium plays a variety of biological activities in the human body. The particle size of strontium ions is tiny, and it is easier to penetrate into the skin and hair than organic macromolecules. The present invention creatively adds strontium-containing compounds into shampoo products, and uses strontium elements to promote collagen formation, induce angiogenesis, promote cell endothelial proliferation and other biological activities to maintain scalp vitality, nourish hair follicles, and maintain the basic environment for hair growth, thereby growing stronger and healthier hair. Strontium enters the human body through the scalp and also plays a role in supplementing trace elements.

同时，本发明还考虑到，洗发水中多使用阴离子表面活性剂，而锶离子属阳离子性强电解质碱土金属，为了避免阴离子表面活性剂与锶离子发生中和反应产生的以下不利影响：(1)表面活性剂和锶离子的功效都不能充分发挥；(2)洗发水体系不稳定，容易产生破乳分层的现象；(3)增稠剂难以起到增稠的作用，洗发水粘度难以提高，本发明将组分一分为二，提出双组分分开包装，使用时共同泵出混合，充分保证各组分在体系中的稳定性以及功效的发挥。为解决洗发水中金属离子破坏乳化体系的问题，目前大多数的做法是添加金属离子螯合剂，如EDTA盐，但是EDTA盐已被认定为持久性有机污染物，对环境不友好，本发明因此也克服了此技术弊端。At the same time, the present invention also takes into account that anionic surfactants are mostly used in shampoos, and strontium ions are cationic strong electrolyte alkaline earth metals. In order to avoid the following adverse effects caused by the neutralization reaction between anionic surfactants and strontium ions: (1) the effects of surfactants and strontium ions cannot be fully exerted; (2) the shampoo system is unstable and prone to demulsification and stratification; (3) the thickener is difficult to play a thickening role and the viscosity of the shampoo is difficult to increase. The present invention divides the components into two, proposes to package the two components separately, and pump them out and mix them together when used, so as to fully ensure the stability of each component in the system and the performance of its efficacy. In order to solve the problem of metal ions destroying the emulsification system in shampoo, most current practices are to add metal ion chelating agents, such as EDTA salts, but EDTA salts have been identified as persistent organic pollutants and are not environmentally friendly. Therefore, the present invention also overcomes this technical drawback.

本洗发水利用含锶化合物、其他调理剂、表面活性剂、增稠剂、润滑剂、增泡剂、保湿剂、pH调节剂、防腐剂等成分复合而成，各原料相互促进，共同使得该洗发水兼具头皮清洁与养护、发丝清洁与养护的功效。The shampoo is compounded with strontium compounds, other conditioning agents, surfactants, thickeners, lubricants, foam enhancers, moisturizers, pH adjusters, preservatives and other ingredients. The ingredients promote each other, making the shampoo have the effects of scalp cleansing and care, and hair cleansing and care.

所述至少两种的组合例如氯化锶和六水合氯化锶的组合、氯化锶和醋酸锶的组合、氯化锶和氢氧化锶的组合、氯化锶和柠檬酸锶的组合等，其他任意的组合方式均可选择，在此便不再一一赘述。The combination of at least two of the above-mentioned compounds may include, for example, a combination of strontium chloride and strontium chloride hexahydrate, a combination of strontium chloride and strontium acetate, a combination of strontium chloride and strontium hydroxide, a combination of strontium chloride and strontium citrate, and any other combinations may be selected and will not be described in detail here.

优选地，所述第二组分中的调理剂还包括铜肽。Preferably, the conditioning agent in the second component also includes copper peptides.

铜肽能促进毛乳头细胞增殖和头发生长因子表达，对抗毛囊老化、防止脱发，作为强有力的组织保护和消炎剂，保护受伤组织免受氧化进一步损害，具有促进头发生长、伤口愈合等作用。还对维持皮肤支撑结构(胶原蛋白、糖蛋白、弹性蛋白等)有促进作用，起到减少粗细皱纹的作用，还具有抑制炎症的作用。本发明还创造性地发现铜肽与含锶化合物配合使用，在头皮养护方面具有协同增效作用。Copper peptides can promote the proliferation of hair papilla cells and the expression of hair growth factors, fight against hair follicle aging and prevent hair loss. As a powerful tissue protector and anti-inflammatory agent, they protect injured tissues from further damage by oxidation, and have the effects of promoting hair growth and wound healing. They also promote the maintenance of skin support structures (collagen, glycoprotein, elastin, etc.), reduce coarse and fine wrinkles, and inhibit inflammation. The present invention also creatively discovered that the use of copper peptides in combination with strontium-containing compounds has a synergistic effect in scalp care.

优选地，所述铜肽与含锶化合物的质量比为1:(10-50)，例如1:10、1:12、1:15、1:18、1:20、1:22、1:25、1:28、1:30、1:32、1:35、1:40、1:45、1:50等，该数值范围内的其他具体点值均可选择，在此便不再一一赘述。Preferably, the mass ratio of the copper peptide to the strontium-containing compound is 1:(10-50), for example 1:10, 1:12, 1:15, 1:18, 1:20, 1:22, 1:25, 1:28, 1:30, 1:32, 1:35, 1:40, 1:45, 1:50, etc. Other specific point values within this numerical range can be selected and will not be described here one by one.

优选地，所述第一组分中的调理剂包括尿囊素、铁皮石斛提取物、甘油椰油酸酯、瓜儿胶羟丙基三甲基氯化铵、水解丝蛋白或泛醇中的任意一种或至少两种的组合。Preferably, the conditioning agent in the first component includes any one or a combination of at least two of allantoin, Dendrobium officinale extract, glyceryl cocoate, guar hydroxypropyltrimonium chloride, hydrolyzed silk protein or panthenol.

所述至少两种的组合例如尿囊素和铁皮石斛提取物的组合、铁皮石斛提取物和甘油椰油酸酯的组合、瓜儿胶羟丙基三甲基氯化铵和水解丝蛋白的组合等，其他任意的组合方式均可选择，在此便不再一一赘述。The combination of at least two of the above mentioned ingredients, for example, a combination of allantoin and a Dendrobium officinale extract, a combination of a Dendrobium officinale extract and glyceryl cocoate, a combination of guar hydroxypropyltrimonium chloride and hydrolyzed silk protein, etc., any other combinations may be selected and will not be described in detail here.

优选地，所述第一组分中的调理剂包括尿囊素、铁皮石斛提取物、甘油椰油酸酯、瓜儿胶羟丙基三甲基氯化铵、水解丝蛋白和泛醇的组合。Preferably, the conditioning agent in the first component comprises a combination of allantoin, Dendrobium officinale extract, glyceryl cocoate, guar hydroxypropyltrimonium chloride, hydrolyzed silk protein and panthenol.

其中，水解丝蛋白可与发丝受损处暴露的蛋白基团交联，修复损伤，提升发丝强韧性；泛醇是一种维生素B5衍生物，通常被称为“前维生素B5”，可以刺激皮肤细胞分裂再生，还能防止头发开叉以及增加头发的密度，提高发质的光泽度；瓜儿胶羟丙基三甲基氯化铵起抗静电和成膜剂的作用，洗发后使发丝具有更好的梳理性；甘油椰油酸酯可用于表面活性剂体系补充油脂，与油脂有互溶性，且黏度低，延展性好，对皮肤渗透性好，能够滋润肌肤，同时增加头发的润滑感，维护头皮和头发的油脂平衡；铁皮石斛提取物对于皮肤的补水功能是非常强大的，且其含有的水溶性多糖有着很好的抗氧化作用，能够增强皮肤的免疫功能，还能抗菌消炎、修复皮肤损伤；尿囊素可以让秀发柔顺不分叉。Among them, hydrolyzed silk protein can cross-link with the protein groups exposed in the damaged parts of the hair, repair the damage and improve the strength of the hair; panthenol is a vitamin B5 derivative, often called "provitamin B5", which can stimulate the division and regeneration of skin cells, prevent split ends, increase hair density and improve the gloss of hair; guar hydroxypropyltrimonium chloride acts as an antistatic and film-forming agent, making the hair more combable after shampooing; glyceryl cocoate can be used in the surfactant system to supplement oil, is miscible with oil, has low viscosity, good ductility, good skin permeability, can moisturize the skin, increase the lubricity of the hair, and maintain the oil balance of the scalp and hair; the extract of Dendrobium officinale has a very strong moisturizing function for the skin, and the water-soluble polysaccharides it contains have a good antioxidant effect, can enhance the skin's immune function, and can also fight bacteria and inflammation and repair skin damage; allantoin can make hair smooth and not split.

本发明所涉及的洗发水中第一组分中的调理剂优选上述组合方式能使洗发水在头皮滋养和头发滋养方面的功效更佳。The conditioning agent in the first component of the shampoo of the present invention is preferably in the above-mentioned combination so that the shampoo can have better effects in scalp nourishment and hair nourishment.

优选地，所述表面活性剂包括月桂醇聚醚硫酸脂铵、椰油酰水解燕麦蛋白钾、辛基/癸基葡糖苷、月桂基葡糖苷、α-烯基磺酸钠、甲基椰油酰基牛磺酸钠、蓖麻醇酸酰胺丙基三甲基氯化铵、聚乙二醇硬脂酸酯、鲸蜡硬脂醇中的任意一种或至少两种的组合。Preferably, the surfactant includes any one or a combination of at least two of ammonium laureth sulfate, potassium cocoyl hydrolyzed oat protein, octyl/decyl glucoside, lauryl glucoside, sodium α-olefin sulfonate, sodium methyl cocoyl taurate, ricinoleic acid amide propyl trimethylammonium chloride, polyethylene glycol stearate, and cetearyl alcohol.

所述至少两种的组合例如月桂醇聚醚硫酸脂铵和椰油酰水解燕麦蛋白钾的组合、月桂基葡糖苷和α-烯基磺酸钠的组合、甲基椰油酰基牛磺酸钠和蓖麻醇酸酰胺丙基三甲基氯化铵的组合等，其他任意的组合方式均可选择，在此便不再一一赘述。The combination of at least two of the above mentioned ingredients, for example, the combination of ammonium laureth sulfate and potassium cocoyl hydrolyzed oat protein, the combination of lauryl glucoside and sodium α-olefin sulfonate, the combination of sodium methyl cocoyl taurate and ricinoleyl acid amide propyl trimethylammonium chloride, etc., any other combinations may be selected and will not be described in detail here.

其中月桂醇聚醚硫酸脂铵、椰油酰水解燕麦蛋白钾、辛基/癸基葡糖苷、月桂基葡糖苷、α-烯基磺酸钠、甲基椰油酰基牛磺酸钠、蓖麻醇酸酰胺丙基三甲基氯化铵主要起到清洁去污和发泡的功能；其中聚乙二醇硬脂酸酯、鲸蜡硬脂醇主要起到保持体系油水平衡，稳定体系的功效。Among them, ammonium laureth sulfate, potassium cocoyl hydrolyzed oat protein, capryl/decyl glucoside, lauryl glucoside, sodium α-olefin sulfonate, sodium methyl cocoyl taurate, and ricinoleic acid amide propyl trimethylammonium chloride mainly play the role of cleaning, decontamination and foaming; among them, polyethylene glycol stearate and cetearyl alcohol mainly play the role of maintaining the oil-water balance of the system and stabilizing the system.

作为本发明的优选技术方案，以所述具有头皮滋养功效的双组分洗发水的质量为100％计，所述第一组分包括表面活性剂15-30％、增泡剂5-15％、调理剂1-10％、增稠剂1-5％、润滑剂1-5％、防腐剂0.1-0.5％、pH调节剂0.05-0.5％和水；As a preferred technical solution of the present invention, based on the mass of the two-component shampoo with scalp nourishing effect as 100%, the first component includes 15-30% surfactant, 5-15% foaming agent, 1-10% conditioner, 1-5% thickener, 1-5% lubricant, 0.1-0.5% preservative, 0.05-0.5% pH adjuster and water;

所述第二组分包括保湿剂1-5％、调理剂1-5％和水5-15％。The second component includes 1-5% moisturizer, 1-5% conditioner and 5-15% water.

所述表面活性剂的质量百分含量可以为15％、18％、20％、22％、25％、28％、30％等。所述增泡剂的质量百分含量可以为5％、8％、10％、12％、15％等。所述第一组分中的调理剂的质量百分含量可以为1％、2％、3％、4％、5％、6％、7％、8％、9％、10％等。所述增稠剂的质量百分含量可以为1％、2％、3％、4％、5％等。所述润滑剂的质量百分含量可以为1％、2％、3％、4％、5％等。所述防腐剂的质量百分含量可以为0.1％、0.2％、0.3％、0.4％、0.5％等。所述pH调节剂的质量百分含量可以为0.05％、0.1％、0.2％、0.3％、0.4％、0.5％等。所述保湿剂的质量百分含量可以为1％、2％、3％、4％、5％等。所述第二组分中的调理剂的质量百分含量可以为1％、2％、3％、4％、5％等。所述第二组分中的水的质量百分含量可以为5％、7％、8％、9％、10％、12％、14％、15％等。The mass percentage of the surfactant can be 15%, 18%, 20%, 22%, 25%, 28%, 30%, etc. The mass percentage of the foaming agent can be 5%, 8%, 10%, 12%, 15%, etc. The mass percentage of the conditioning agent in the first component can be 1%, 2%, 3%, 4%, 5%, 6%, 7%, 8%, 9%, 10%, etc. The mass percentage of the thickener can be 1%, 2%, 3%, 4%, 5%, etc. The mass percentage of the lubricant can be 1%, 2%, 3%, 4%, 5%, etc. The mass percentage of the preservative can be 0.1%, 0.2%, 0.3%, 0.4%, 0.5%, etc. The mass percentage of the pH adjuster can be 0.05%, 0.1%, 0.2%, 0.3%, 0.4%, 0.5%, etc. The mass percentage of the moisturizing agent can be 1%, 2%, 3%, 4%, 5%, etc. The mass percentage of the conditioning agent in the second component can be 1%, 2%, 3%, 4%, 5%, etc. The mass percentage of water in the second component can be 5%, 7%, 8%, 9%, 10%, 12%, 14%, 15%, etc.

上述各项数值范围内的其他具体点值均可选择，在此便不再一一赘述。Other specific point values within the above numerical ranges can be selected and will not be described in detail here.

优选地，所述增泡剂包括椰油酰胺丙基甜菜碱、烷基醇酰胺、丙二醇单月桂酸酯、丙烯酸(酯)类/VA共聚物中的任意一种或至少两种的组合。Preferably, the foaming agent includes any one of cocamidopropyl betaine, alkyl alcohol amide, propylene glycol monolaurate, and acrylic acid (ester)/VA copolymer, or a combination of at least two thereof.

所述至少两种的组合例如椰油酰胺丙基甜菜碱和烷基醇酰胺的组合、烷基醇酰胺和丙二醇单月桂酸酯的组合等，其他任意的组合方式均可选择，在此便不再一一赘述。The combination of at least two of the above mentioned components, for example, the combination of cocamidopropyl betaine and alkyl alcohol amide, the combination of alkyl alcohol amide and propylene glycol monolaurate, and any other combinations may be selected and will not be described in detail here.

优选地，所述增稠剂包括聚季铵盐-7、PEG-150二硬脂酸酯、黄原胶、瓜尔胶、海藻胶、羟乙基纤维素中的任意一种或至少两种的组合。Preferably, the thickener includes any one of polyquaternium-7, PEG-150 distearate, xanthan gum, guar gum, alginate, and hydroxyethyl cellulose, or a combination of at least two thereof.

所述至少两种的组合例如聚季铵盐-7和PEG-150二硬脂酸酯的组合、黄原胶和瓜尔胶的组合、海藻胶和羟乙基纤维素的组合等，其他任意的组合方式均可选择，在此便不再一一赘述。The combination of at least two of the above mentioned types, for example, the combination of polyquaternium-7 and PEG-150 distearate, the combination of xanthan gum and guar gum, the combination of alginate and hydroxyethyl cellulose, etc., any other combinations may be selected and will not be described in detail here.

优选地，所述润滑剂包括硅油，例如氨端聚二甲基硅氧烷(和)西曲氯铵(和)十三烷醇聚醚-12、聚二甲基硅氧烷(和)月桂醇聚醚-23(和)C12-15链烷醇聚醚-3、环五聚二甲基硅氧烷(和)聚二甲基硅氧烷醇等。Preferably, the lubricant includes silicone oil, such as amodimethicone (and) cetrimonium chloride (and) trideceth-12, dimethicone (and) laureth-23 (and) C12-15 polyether-3, cyclopentasiloxane (and) dimethiconol, and the like.

优选地，所述保湿剂包括透明质酸、透明质酸钠、丙二醇、丙三醇、泛醇中的任意一种或至少两种的组合。Preferably, the moisturizing agent includes any one of hyaluronic acid, sodium hyaluronate, propylene glycol, glycerol, and panthenol, or a combination of at least two thereof.

所述至少两种的组合例如透明质酸和透明质酸钠的组合、透明质酸钠和丙二醇的组合、丙三醇和泛醇的组合等，其他任意的组合方式均可选择，在此便不再一一赘述。The combination of at least two of the above mentioned types can be, for example, a combination of hyaluronic acid and sodium hyaluronate, a combination of sodium hyaluronate and propylene glycol, a combination of glycerol and panthenol, or any other combination can be selected, which will not be described in detail here.

优选地，所述透明质酸为大分子透明质酸、中分子透明质酸和小分子透明质酸的组合。Preferably, the hyaluronic acid is a combination of large molecular hyaluronic acid, medium molecular hyaluronic acid and small molecular hyaluronic acid.

优选地，所述透明质酸盐为大分子透明质酸盐、中分子透明质酸盐和小分子透明质酸盐的组合。Preferably, the hyaluronate is a combination of macromolecular hyaluronate, medium molecular hyaluronate and small molecular hyaluronate.

所述大分子透明质酸是指分子量大于5000的透明质酸、所述中分子透明质酸是指分子量1000-5000的透明质酸，所述小分子透明质酸是指分子量小于1000的透明质酸。The macromolecular hyaluronic acid refers to hyaluronic acid with a molecular weight greater than 5000, the medium-molecular hyaluronic acid refers to hyaluronic acid with a molecular weight of 1000-5000, and the small-molecular hyaluronic acid refers to hyaluronic acid with a molecular weight less than 1000.

其中大分子透明质酸可在头皮及发丝表面形成一层透气的薄膜，使皮肤光滑湿润，并可阻隔外来细菌、灰尘、紫外线的侵入，保护皮肤免受侵害；中分子透明质酸可以紧致头皮，长久保湿；小分子透明质酸能渗入真皮，具有轻微扩张毛细血管，增加血液循环、改善中间代谢、促进头皮营养吸收作用，可增加皮肤弹性，延缓皮肤衰老。而且透明质酸可以与含锶化合物中的锶离子结合，反应生成透明质酸锶，可以使锶这种金属离子能够更加稳定地存在于洗发水体系当中，避免形成其他易结晶的锶盐而析出。Among them, large molecular hyaluronic acid can form a breathable film on the surface of scalp and hair, making the skin smooth and moisturized, and can block the invasion of foreign bacteria, dust, and ultraviolet rays to protect the skin from damage; medium molecular hyaluronic acid can tighten the scalp and moisturize for a long time; small molecular hyaluronic acid can penetrate into the dermis, slightly dilate capillaries, increase blood circulation, improve intermediate metabolism, promote scalp nutrient absorption, increase skin elasticity, and delay skin aging. Moreover, hyaluronic acid can combine with strontium ions in strontium-containing compounds to react and generate strontium hyaluronic acid, which can make the metal ion strontium more stable in the shampoo system and avoid the formation of other strontium salts that are easy to crystallize and precipitate.

优选地，所述第一组分还包括芳香剂和/或调色剂。Preferably, the first component further comprises a fragrance and/or a colorant.

所述芳香剂例如香精，用于增加产品的香味，洗发后香味滞留，令人愉悦。所述调色剂例如珠光浆，用于调节体系的颜色与光亮。The fragrance, such as essence, is used to increase the fragrance of the product, and the fragrance remains after shampooing, which is pleasant. The colorant, such as pearlescent slurry, is used to adjust the color and brightness of the system.

第二方面，本发明提供一种如第一方面所述的具有头皮滋养功效的双组分洗发水的制备方法，所述制备方法包括：In a second aspect, the present invention provides a method for preparing the two-component shampoo with scalp nourishing effect as described in the first aspect, the preparation method comprising:

分别将第一组分和第二组分中各原料各自混合制得第一组分和第二组分，即得。The raw materials in the first component and the second component are mixed separately to obtain the first component and the second component.

本发明所涉及的具有头皮滋养功效的双组分洗发水的制备方法工艺简单易操作，非常适合大规模化的工业生产。The preparation method of the two-component shampoo with scalp nourishing effect of the present invention has simple process and is easy to operate, and is very suitable for large-scale industrial production.

优选地，所述第一组分的制备方法包括：Preferably, the preparation method of the first component comprises:

(1)将水与表面活性剂、增泡剂和部分调理剂混合，得到组分A；(1) mixing water with a surfactant, a foam enhancer and a portion of a conditioning agent to obtain component A;

(2)将组分A与增稠剂、润滑剂、剩余调理剂混合，得到组分B；(2) mixing component A with a thickener, a lubricant, and remaining conditioning agents to obtain component B;

(3)将组分B与其他剩余原料混合，即得第一组分。(3) Mix component B with other remaining raw materials to obtain the first component.

优选地，步骤(1)所述部分调理剂包括尿囊素和铁皮石斛提取物。Preferably, the partial conditioning agent in step (1) comprises allantoin and Dendrobium officinale extract.

优选地，步骤(1)所述混合在搅拌下进行，所述搅拌在75-90℃(例如75℃、78℃、80℃、82℃、85℃、88℃、90℃等)下进行15-30min(例如15min、17min、18min、20min、23min、25min、30min等)，搅拌速度为20-35r/min(例如20r/min、22r/min、25r/min、30r/min、35r/min等)。上述各项数值范围内的其他具体点值均可选择，在此便不再一一赘述。Preferably, the mixing in step (1) is carried out under stirring, the stirring is carried out at 75-90°C (e.g., 75°C, 78°C, 80°C, 82°C, 85°C, 88°C, 90°C, etc.) for 15-30min (e.g., 15min, 17min, 18min, 20min, 23min, 25min, 30min, etc.), and the stirring speed is 20-35r/min (e.g., 20r/min, 22r/min, 25r/min, 30r/min, 35r/min, etc.). Other specific point values within the above numerical ranges can be selected, and they will not be repeated here one by one.

优选地，步骤(2)所述混合在搅拌下进行，所述搅拌在40-55℃(例如40℃、42℃、45℃、48℃、50℃、52℃、55℃等)下进行15-30min(例如15min、17min、18min、20min、23min、25min、30min等)，搅拌速度为15-30r/min(15r/min、17r/min、18r/min、20r/min、23r/min、25r/min、30r/min等)。上述各项数值范围内的其他具体点值均可选择，在此便不再一一赘述。Preferably, the mixing in step (2) is carried out under stirring, and the stirring is carried out at 40-55°C (e.g., 40°C, 42°C, 45°C, 48°C, 50°C, 52°C, 55°C, etc.) for 15-30min (e.g., 15min, 17min, 18min, 20min, 23min, 25min, 30min, etc.), and the stirring speed is 15-30r/min (15r/min, 17r/min, 18r/min, 20r/min, 23r/min, 25r/min, 30r/min, etc.). Other specific point values within the above numerical ranges can be selected, and they will not be repeated here one by one.

优选地，步骤(3)所述混合在搅拌下进行，所述搅拌在40-55℃(例如40℃、42℃、45℃、48℃、50℃、52℃、55℃等)下进行15-30min(例如15min、17min、18min、20min、23min、25min、30min等)，搅拌速度为15-30r/min(15r/min、17r/min、18r/min、20r/min、23r/min、25r/min、30r/min等)。上述各项数值范围内的其他具体点值均可选择，在此便不再一一赘述。Preferably, the mixing in step (3) is carried out under stirring, and the stirring is carried out at 40-55°C (e.g., 40°C, 42°C, 45°C, 48°C, 50°C, 52°C, 55°C, etc.) for 15-30min (e.g., 15min, 17min, 18min, 20min, 23min, 25min, 30min, etc.), and the stirring speed is 15-30r/min (15r/min, 17r/min, 18r/min, 20r/min, 23r/min, 25r/min, 30r/min, etc.). Other specific point values within the above numerical ranges can be selected, and they will not be repeated here one by one.

优选地，第一组分的pH值为5.5-6.5。Preferably, the pH value of the first component is 5.5-6.5.

优选地，所述第二组分的制备方法包括：将保湿剂、调理剂和水在30-55℃(例如30℃、35℃、40℃、45℃、50℃、55℃等)下搅拌10-40min(例如10min、15min、20min、25min、30min、35min、40min等)，即可。Preferably, the preparation method of the second component comprises: stirring the moisturizer, the conditioner and water at 30-55°C (for example, 30°C, 35°C, 40°C, 45°C, 50°C, 55°C, etc.) for 10-40min (for example, 10min, 15min, 20min, 25min, 30min, 35min, 40min, etc.).

采用上述特定技术参数的制备方法制得的护发素体系稳定，功效持久。The hair conditioner system prepared by the preparation method with the above specific technical parameters is stable and has long-lasting efficacy.

与现有技术相比，本发明具有如下有益效果：Compared with the prior art, the present invention has the following beneficial effects:

本发明创造性地将含锶化合物添加入洗发产品中，利用锶元素促进胶原蛋白形成、诱导血管生成、促进细胞内皮增殖等生物活性来保持头皮活力、滋养毛囊，维护头发生长的基础环境，进而生长出更加强韧、健康的发丝，锶通过头皮进入人体还起到了补充微量元素的作用。The present invention creatively adds strontium-containing compounds into shampoo products, and utilizes the biological activities of strontium to promote collagen formation, induce angiogenesis, promote cell endothelial proliferation, etc. to maintain scalp vitality, nourish hair follicles, and maintain the basic environment for hair growth, thereby growing stronger and healthier hair. Strontium enters the human body through the scalp and also plays a role in supplementing trace elements.

进一步地，利用铜肽能促进毛乳头细胞增殖和头发生长因子表达，对抗毛囊老化、防止脱发，作为强有力的组织保护和消炎剂，保护受伤组织免受氧化进一步损害，具有促进头发生长、伤口愈合等作用，本发明还创造性地将铜肽与含锶化合物配合使用，使其在头皮养护方面具有协同增效作用。Furthermore, copper peptides can promote the proliferation of hair papilla cells and the expression of hair growth factors, fight against hair follicle aging and prevent hair loss. As a powerful tissue protector and anti-inflammatory agent, it protects injured tissues from further oxidative damage and has the effects of promoting hair growth and wound healing. The present invention also creatively combines copper peptides with strontium-containing compounds to achieve a synergistic effect in scalp care.

同时，本发明还考虑到，洗发水中多使用阴离子表面活性剂，而锶离子属阳离子性强电解质碱土金属，为了避免阴离子表面活性剂与锶离子发生中和反应产生的以下不利影响：(1)表面活性剂和锶离子的功效都不能充分发挥；(2)洗发水体系不稳定，容易产生破乳分层的现象；(3)增稠剂难以起到增稠的作用，洗发水粘度难以提高，本发明将组分一分为二，提出双组分分开包装，使用时共同泵出混合，充分保证各组分在体系中的稳定性以及功效的发挥。为解决洗发水中金属离子破坏乳化体系的问题，目前大多数的做法是添加金属离子螯合剂，如EDTA盐，但是EDTA盐已被认定为持久性有机污染物，对环境不友好，本发明因此也克服了此技术弊端。At the same time, the present invention also takes into account that anionic surfactants are mostly used in shampoos, and strontium ions are cationic strong electrolyte alkaline earth metals. In order to avoid the following adverse effects caused by the neutralization reaction between anionic surfactants and strontium ions: (1) the effects of surfactants and strontium ions cannot be fully exerted; (2) the shampoo system is unstable and prone to demulsification and stratification; (3) the thickener is difficult to play a thickening role and the viscosity of the shampoo is difficult to increase. The present invention divides the components into two, proposes to package the two components separately, and pump them out and mix them together when used, so as to fully ensure the stability of each component in the system and the performance of its efficacy. In order to solve the problem of metal ions destroying the emulsification system in shampoo, most current practices are to add metal ion chelating agents, such as EDTA salts, but EDTA salts have been identified as persistent organic pollutants and are not environmentally friendly. Therefore, the present invention also overcomes this technical drawback.

具体实施方式DETAILED DESCRIPTION

为更进一步阐述本发明所采取的技术手段及其效果，以下结合本发明的优选实施例来进一步说明本发明的技术方案，但本发明并非局限在实施例范围内。In order to further explain the technical means and effects adopted by the present invention, the technical solution of the present invention is further described below in conjunction with the preferred embodiments of the present invention, but the present invention is not limited to the scope of the embodiments.

下述实施例和对比例所涉及的部分原料来源信息如下：The sources of some raw materials involved in the following examples and comparative examples are as follows:

水解丝蛋白为购自郑州宇控生物科技有限公司的水解蚕丝蛋白；The hydrolyzed silk protein was purchased from Zhengzhou Yukong Biotechnology Co., Ltd.

氨基硅油乳液为MEM-0949氨基硅油乳液；The amino silicone oil emulsion is MEM-0949 amino silicone oil emulsion;

有机硅乳液为SSE-762有机硅乳液；The silicone emulsion is SSE-762 silicone emulsion;

透明质酸为大分子透明质酸(曲阜市海昕生物制品有限公司)、中分子透明质酸(郑州明瑞化工产品有限公司)、小分子透明质酸(西安千诺生物科技有限公司)以质量比1:2:1的混合物；Hyaluronic acid is a mixture of macromolecular hyaluronic acid (Qufu Haixin Biological Products Co., Ltd.), medium molecular hyaluronic acid (Zhengzhou Mingrui Chemical Products Co., Ltd.), and small molecular hyaluronic acid (Xi'an Qiannuo Biotechnology Co., Ltd.) in a mass ratio of 1:2:1;

防腐剂为禾大馨醇68与馨鲜酮以质量比1:1的混合物；The preservative is a mixture of Heda Xinchun 68 and Xinxian ketone in a mass ratio of 1:1;

铁皮石斛提取物为购自西安瑞林生物科技有限公司提取率为50:1的产品；Dendrobium officinale extract was purchased from Xi'an Ruilin Biotechnology Co., Ltd. with an extraction ratio of 50:1;

其他原料均通过市售途径购买获得。Other raw materials were purchased from commercial sources.

实施例1Example 1

本实施例提供一种具有头皮滋养功效的双组分洗发水，配方表如下表所示：This embodiment provides a two-component shampoo with scalp nourishing effect, and the formula is shown in the following table:

其制备方法如下：The preparation method is as follows:

(1)将水与表面活性剂、增泡剂和尿囊素、铁皮石斛提取物在80℃下混合搅拌20min，搅拌速度为30r/min，得到组分A；(1) mixing water, a surfactant, a foaming agent, allantoin, and a Dendrobium officinale extract at 80° C. and stirring for 20 min at a stirring speed of 30 r/min to obtain component A;

(2)将组分A与增稠剂、润滑剂、甘油椰油酸酯、瓜儿胶羟丙基三甲基氯化铵、水解丝蛋白、泛醇在45℃下混合搅拌30min，搅拌速度为20r/min，得到组分B；(2) mixing component A with a thickener, a lubricant, glyceryl cocoate, guar hydroxypropyltrimonium chloride, hydrolyzed silk protein, and panthenol at 45° C. and stirring for 30 min at a stirring speed of 20 r/min to obtain component B;

(3)将组分B与第一组分的其他剩余原料在45℃下混合搅拌20min，搅拌速度为20r/min，即得第一组分。(3) Component B and the remaining raw materials of the first component are mixed and stirred at 45° C. for 20 min at a stirring speed of 20 r/min to obtain the first component.

(4)将第二组分的各原料按配比在45℃下混合搅拌25min，搅拌速度为30r/min，得到第二组分。(4) The raw materials of the second component are mixed and stirred according to the proportions at 45° C. for 25 min at a stirring speed of 30 r/min to obtain the second component.

(5)进行灌装，采用专门的双组分洗发水泵头瓶，将第一组分和第二组分分别装在泵头瓶的不同位置内。使用时按压泵头，两组分按照设计好的比例同时被挤出。(5) Filling: Use a special two-component shampoo pump bottle, and place the first component and the second component in different positions of the pump bottle. When using, press the pump head, and the two components are squeezed out at the same time according to the designed ratio.

实施例2Example 2

本实施例提供一种具有头皮滋养功效的双组分洗发水，配方表如下表所示：This embodiment provides a two-component shampoo with scalp nourishing effect, and the formula is shown in the following table:

其制备方法如下：The preparation method is as follows:

(1)将水与表面活性剂、增泡剂和尿囊素、铁皮石斛提取物在85℃下混合搅拌30min，搅拌速度为20r/min，得到组分A；(1) mixing water, a surfactant, a foaming agent, allantoin, and a Dendrobium officinale extract at 85° C. and stirring at a stirring speed of 20 r/min for 30 min to obtain component A;

(2)将组分A与增稠剂、润滑剂、甘油椰油酸酯、瓜儿胶羟丙基三甲基氯化铵、水解丝蛋白、泛醇在50℃下混合搅拌20min，搅拌速度为30r/min，得到组分B；(2) mixing component A with a thickener, a lubricant, glyceryl cocoate, guar hydroxypropyltrimonium chloride, hydrolyzed silk protein, and panthenol at 50° C. and stirring for 20 min at a stirring speed of 30 r/min to obtain component B;

(3)将组分B与第一组分的其他剩余原料在50℃下混合搅拌30min，搅拌速度为15r/min，即得第一组分。(3) Component B and the remaining raw materials of the first component are mixed and stirred at 50° C. for 30 min at a stirring speed of 15 r/min to obtain the first component.

(4)将第二组分的各原料按配比在50℃下混合搅拌30min，搅拌速度为15r/min，得到第二组分。(4) The raw materials of the second component are mixed and stirred according to the proportion at 50° C. for 30 min at a stirring speed of 15 r/min to obtain the second component.

(5)进行灌装，采用专门的双组分洗发水泵头瓶，将第一组分和第二组分分别装在泵头瓶的不同位置内。使用时按压泵头，两组分按照设计好的比例同时被挤出。(5) Filling: Use a special two-component shampoo pump bottle, and place the first component and the second component in different positions of the pump bottle. When using, press the pump head, and the two components are squeezed out at the same time according to the designed ratio.

实施例3Example 3

本实施例提供一种具有头皮滋养功效的双组分洗发水，配方表与实施例1的区别仅在于将氯化锶3％、铜肽0.1％替换为氯化锶3.1％，其他组分及含量均保持不变。其制备方法参照实施例1。This embodiment provides a two-component shampoo with scalp nourishing effect. The difference between the formula table and Example 1 is that 3% strontium chloride and 0.1% copper peptide are replaced with 3.1% strontium chloride, and the other components and contents remain unchanged. The preparation method thereof is referred to Example 1.

实施例4Example 4

本实施例提供一种具有头皮滋养功效的双组分洗发水，配方表与实施例1的区别仅在于将氯化锶3％、铜肽0.1％替换为铜肽3.1％，其他组分及含量均保持不变。其制备方法参照实施例1。This embodiment provides a two-component shampoo with scalp nourishing effect. The difference between the formula table and Example 1 is that 3% strontium chloride and 0.1% copper peptide are replaced with 3.1% copper peptide, and the other components and contents remain unchanged. The preparation method thereof is referred to Example 1.

实施例5Example 5

本实施例提供一种具有头皮滋养功效的双组分洗发水，配方表与实施例1的区别仅在于尿囊素0.15％、铁皮石斛提取物0.15％、甘油椰油酸酯1％、瓜儿胶羟丙基三甲基氯化铵0.5％、水解丝蛋白3％、泛醇0.5％替换为尿囊素0.3％、甘油椰油酸酯1％、瓜儿胶羟丙基三甲基氯化铵0.5％、水解丝蛋白3％、泛醇0.5％，其他组分及含量均保持不变。其制备方法参照实施例1。This embodiment provides a two-component shampoo with scalp nourishing effect. The formula table is different from that of Example 1 only in that 0.15% of allantoin, 0.15% of Dendrobium officinale extract, 1% of glyceryl cocoate, 0.5% of guar hydroxypropyltrimonium chloride, 3% of hydrolyzed silk protein, and 0.5% of panthenol are replaced with 0.3% of allantoin, 1% of glyceryl cocoate, 0.5% of guar hydroxypropyltrimonium chloride, 3% of hydrolyzed silk protein, and 0.5% of panthenol, and the other components and contents remain unchanged. The preparation method thereof is referred to Example 1.

实施例6Example 6

本实施例提供一种具有头皮滋养功效的双组分洗发水，配方表与实施例1的区别仅在于尿囊素0.15％、铁皮石斛提取物0.15％、甘油椰油酸酯1％、瓜儿胶羟丙基三甲基氯化铵0.5％、水解丝蛋白3％、泛醇0.5％替换为铁皮石斛提取物0.3％、甘油椰油酸酯1％、瓜儿胶羟丙基三甲基氯化铵0.5％、水解丝蛋白3％、泛醇0.5％，其他组分及含量均保持不变。其制备方法参照实施例1。This embodiment provides a two-component shampoo with scalp nourishing effect. The formula table is different from that of Example 1 only in that 0.15% of allantoin, 0.15% of Dendrobium officinale extract, 1% of glyceryl cocoate, 0.5% of guar hydroxypropyltrimonium chloride, 3% of hydrolyzed silk protein, and 0.5% of panthenol are replaced with 0.3% of Dendrobium officinale extract, 1% of glyceryl cocoate, 0.5% of guar hydroxypropyltrimonium chloride, 3% of hydrolyzed silk protein, and 0.5% of panthenol, and the other components and contents remain unchanged. The preparation method thereof is referred to Example 1.

实施例7Example 7

本实施例提供一种具有头皮滋养功效的双组分洗发水，配方表与实施例1的区别仅在于尿囊素0.15％、铁皮石斛提取物0.15％、甘油椰油酸酯1％、瓜儿胶羟丙基三甲基氯化铵0.5％、水解丝蛋白3％、泛醇0.5％替换为尿囊素0.15％、铁皮石斛提取物0.15％、瓜儿胶羟丙基三甲基氯化铵1％、水解丝蛋白3％、泛醇1％，其他组分及含量均保持不变。其制备方法参照实施例1。This embodiment provides a two-component shampoo with scalp nourishing effect. The formula table is different from that of Example 1 only in that 0.15% allantoin, 0.15% Dendrobium officinale extract, 1% glyceryl cocoate, 0.5% guar hydroxypropyltrimonium chloride, 3% hydrolyzed silk protein, and 0.5% panthenol are replaced with 0.15% allantoin, 0.15% Dendrobium officinale extract, 1% guar hydroxypropyltrimonium chloride, 3% hydrolyzed silk protein, and 1% panthenol, and the other components and contents remain unchanged. The preparation method thereof is referred to Example 1.

实施例8Example 8

本实施例提供一种具有头皮滋养功效的双组分洗发水，配方表与实施例1的区别仅在于尿囊素0.15％、铁皮石斛提取物0.15％、甘油椰油酸酯1％、瓜儿胶羟丙基三甲基氯化铵0.5％、水解丝蛋白3％、泛醇0.5％替换为尿囊素0.15％、铁皮石斛提取物0.15％、甘油椰油酸酯2％、水解丝蛋白3％，其他组分及含量均保持不变。其制备方法参照实施例1。This embodiment provides a two-component shampoo with scalp nourishing effect. The formula table is different from that of Example 1 only in that 0.15% allantoin, 0.15% Dendrobium officinale extract, 1% glyceryl cocoate, 0.5% guar hydroxypropyltrimonium chloride, 3% hydrolyzed silk protein, and 0.5% panthenol are replaced with 0.15% allantoin, 0.15% Dendrobium officinale extract, 2% glyceryl cocoate, and 3% hydrolyzed silk protein, and the other components and contents remain unchanged. The preparation method thereof is referred to Example 1.

对比例1Comparative Example 1

本对比例提供一种双组分洗发水，配方表与实施例1的区别仅在于不含有氯化锶，其含量由水补足，其他组分及含量均保持不变。其制备方法参照实施例1。This comparative example provides a two-component shampoo, the formula of which differs from that of Example 1 only in that it does not contain strontium chloride, the content of which is supplemented by water, and the other components and contents remain unchanged. The preparation method thereof is the same as that of Example 1.

对比例2Comparative Example 2

本对比例提供一种洗发水，配方表与实施例1相同，制备方法如下：This comparative example provides a shampoo, the formula table is the same as that of Example 1, and the preparation method is as follows:

(1)将水与表面活性剂、增泡剂和尿囊素、铁皮石斛提取物在80℃下混合搅拌20min，搅拌速度为30r/min，得到组分A；(1) mixing water, a surfactant, a foaming agent, allantoin, and a Dendrobium officinale extract at 80° C. and stirring for 20 min at a stirring speed of 30 r/min to obtain component A;

(2)将组分A与增稠剂、润滑剂、甘油椰油酸酯、瓜儿胶羟丙基三甲基氯化铵、水解丝蛋白、泛醇在45℃下混合搅拌30min，搅拌速度为20r/min，得到组分B；(2) mixing component A with a thickener, a lubricant, glyceryl cocoate, guar hydroxypropyltrimonium chloride, hydrolyzed silk protein, and panthenol at 45° C. and stirring for 30 min at a stirring speed of 20 r/min to obtain component B;

(3)将组分B与第一组分的其他剩余原料以及第二组分的所有原料在45℃下混合搅拌30min，搅拌速度为25r/min，即得所述洗发水。(3) Component B, the remaining raw materials of the first component and all the raw materials of the second component are mixed and stirred at 45° C. for 30 min at a stirring speed of 25 r/min to obtain the shampoo.

测试例1Test Example 1

对实施例1-8制得的洗发水进行安全性能评估：Safety performance evaluation of the shampoos prepared in Examples 1-8:

选取符合要求的社会志愿者80名，年龄20-45岁，随机分为8组，每组5名女性和5名男性，按组分别试用实施例1-8制得的洗发水，放入斑试器小室内，对照孔不做任何处理。将加有受试物的斑试器用低致敏胶带贴敷于受试者的前臂内侧，用手掌轻压使之均匀地贴敷于皮肤上，持续24h。分别于去除受试物斑器后30min(待压痕消失后)、24h和48h按表1标准观察皮肤反应。试验结果见表2。80 social volunteers who met the requirements, aged 20-45 years old, were selected and randomly divided into 8 groups, each group had 5 women and 5 men, and the shampoos prepared in Examples 1-8 were tried in each group, and placed in the small chamber of the spot tester, and the control well was not treated in any way. The spot tester with the test substance was applied to the inner side of the forearm of the subject with a low-allergenic tape, and the palm of the hand was gently pressed to make it evenly applied to the skin for 24 hours. The skin reaction was observed according to the standards in Table 1 at 30 minutes (after the indentation disappears), 24 hours and 48 hours after the test substance spot tester was removed. The test results are shown in Table 2.

表1Table 1

表2Table 2

结果显示：本发明的实施例1-8都是阴性反应，说明本发明所涉及的洗发水安全温和，不会产生皮肤刺激性、致敏性等不良反应。The results show that Examples 1-8 of the present invention all have negative reactions, indicating that the shampoo of the present invention is safe and mild, and will not cause adverse reactions such as skin irritation and sensitization.

测试例2Test Example 2

对实施例1-8和对比例1-2制得的洗发水进行控油效果测试：The oil control effect of the shampoos prepared in Examples 1-8 and Comparative Examples 1-2 was tested:

选取100名志愿者，年龄25-50岁的男士，随机分成10组，每组10人，每组分别取同等适量实施例1-8和对比例1-2提供的洗发水清洁头皮，试验前两天不清洁头发。测试期间禁止漂染头发，不能使用其他护理产品，除特殊情况，受试者不能停止使用产品。采用SEBUMETER采集头皮油脂含量来评价头皮油脂分泌状态。SEBUMETER法是基于光度计原理，一种0.1mm厚的特殊消光胶带吸收人体皮肤上的油脂后，就会变成半透明的胶带，它的透光量就会发生变化，吸收的油脂越多，透光量就会就会越大，这样就可以测量出头皮油脂的含量。测试条件严格按照在温度22±1℃，使用各待测样品洗发后48h，之后在头皮取5个不同部位用SEBUMETER测量，取平均值，并计算使用各样品后头皮油脂的含量的降低率(结果以平均值呈现)；100 volunteers, men aged 25-50 years old, were selected and randomly divided into 10 groups, 10 people in each group. Each group took the same amount of shampoo provided in Examples 1-8 and Comparative Examples 1-2 to clean the scalp, and did not clean the hair two days before the test. During the test, hair bleaching and dyeing are prohibited, and other care products cannot be used. Except for special circumstances, the subjects cannot stop using the products. SEBUMETER is used to collect the scalp oil content to evaluate the state of scalp oil secretion. The SEBUMETER method is based on the principle of photometer. A 0.1mm thick special matte tape will become a translucent tape after absorbing the oil on human skin, and its light transmittance will change. The more oil it absorbs, the greater the light transmittance will be, so that the scalp oil content can be measured. The test conditions are strictly in accordance with the temperature of 22±1℃. After 48h of shampooing with each sample to be tested, 5 different parts of the scalp are measured with SEBUMETER, the average value is taken, and the reduction rate of the scalp oil content after using each sample is calculated (the results are presented as average values);

具体测试结果如表3所示：The specific test results are shown in Table 3:

表3Table 3

由表1数据可知：本发明所涉及的双组分洗发水具有较好的清洁油脂和长效控油效果，48h后仍可使头皮的油脂量下降18％以上，且含锶化合物与铜肽在维持头皮环境稳定，油水平衡方面具有一定的协同增效作用；同时与对比例2的产品相比，采用双组分设计的洗发水功效更好，具有更显著的控油效果。It can be seen from the data in Table 1 that the two-component shampoo involved in the present invention has good oil cleaning and long-term oil control effects, and can still reduce the amount of oil on the scalp by more than 18% after 48 hours, and the strontium compound and copper peptide have a certain synergistic effect in maintaining the stability of the scalp environment and the balance of oil and water; at the same time, compared with the product of Comparative Example 2, the shampoo with a two-component design has better efficacy and more significant oil control effect.

测试例3Test Example 3

对实施例1-8和对比例1-2制得的洗发水进行头皮清洁效果测试：The scalp cleaning effect of the shampoos prepared in Examples 1-8 and Comparative Examples 1-2 was tested:

选取有明显头皮瘙痒和头屑症状的50名志愿者，年龄25-50岁的男士，随机分成10组，每组5人，每组分别取等量适量的实施例1-8和对比例1-2提供的洗发水清洁头皮和头发；洗发水使用方法为：每人3天洗发1次，共持续10次，最后1次结束后3天进行指标评价。测试期间不使用其他洗发和护发产品。同时实验员在测试人群测试前和测试后观测头皮屑症状，记录各组评分，并计算各组评分平均值；同时观测头皮红肿包数量并询问瘙痒感强烈程度。50 volunteers with obvious scalp itching and dandruff symptoms, males aged 25-50 years old, were randomly divided into 10 groups, 5 people in each group, and each group took an appropriate amount of shampoo provided in Examples 1-8 and Comparative Examples 1-2 to clean the scalp and hair; the shampoo was used as follows: each person shampooed once every 3 days, for a total of 10 times, and the index was evaluated 3 days after the last time. No other shampoo and hair care products were used during the test. At the same time, the experimenter observed the dandruff symptoms of the test population before and after the test, recorded the scores of each group, and calculated the average score of each group; at the same time, the number of scalp redness and swelling was observed and the intensity of the itching was asked.

头屑评价标准：5分-无头屑；4分-小片粉状灰白粗糙鳞屑；3分-小至中等大小屑片；2分-与头皮疏松相连的大而薄的屑片；1分-大的黏着性屑片；0分-与头皮紧密附着的白色至黄色的较厚鳞屑；Dandruff evaluation criteria: 5 points - no dandruff; 4 points - small powdery grayish-white rough scales; 3 points - small to medium-sized scales; 2 points - large, thin scales loosely attached to the scalp; 1 point - large, sticky scales; 0 points - thick white to yellow scales tightly attached to the scalp;

头皮瘙痒红肿评价标准：5分-无现象；4分-不明显；3分-轻微；2分-中等程度；1分-严重程度；0分-非常严重程度。Evaluation criteria for scalp itching and redness: 5 points - no phenomenon; 4 points - not obvious; 3 points - mild; 2 points - moderate; 1 point - severe; 0 point - very severe.

具体测试结果如表4所示(结果以平均值呈现)：The specific test results are shown in Table 4 (the results are presented as average values):

表4Table 4

由表4数据可知：本发明所涉及的双组分洗发水具有较好的去屑和抑制头皮瘙痒红肿的效果，且含锶化合物与铜肽在维持头皮环境稳定，去屑和抑制头皮瘙痒红肿方面具有一定的协同增效作用；同时与对比例2的产品相比，采用双组分设计的洗发水功效更好，具有更显著的上述方面效果。It can be seen from the data in Table 4 that the two-component shampoo involved in the present invention has a good effect of removing dandruff and inhibiting itching and redness of the scalp, and the strontium compound and the copper peptide have a certain synergistic effect in maintaining a stable scalp environment, removing dandruff and inhibiting itching and redness of the scalp; at the same time, compared with the product of Comparative Example 2, the shampoo with a two-component design has better efficacy and more significant effects in the above aspects.

测试例4Test Example 4

随机选取200名正在脱发的一般性脱发患者志愿者(每天平均脱发200根左右)，男女各半，23-55岁，分为实验组1-8组，对比例组1-2组，每组20人，10男10女。使用方法为：每3天使用一次，试验时间均为90天，观察各组志愿者头发的生长情况，各组均取平均值，结果如表5所示(结果以平均值呈现)：200 volunteers with general hair loss (average hair loss of about 200 strands per day) were randomly selected, half male and half female, aged 23-55, and divided into experimental groups 1-8 and comparative groups 1-2, with 20 people in each group, 10 males and 10 females. The method of use is: use once every 3 days, the test time is 90 days, observe the growth of the hair of the volunteers in each group, and take the average value for each group. The results are shown in Table 5 (the results are presented as average values):

表5Table 5

由表5数据可知：本发明所涉及的双组分洗发水具有显著的刺激头皮毛囊，促进头发的生长与新生，防止脱发的效果，且含锶化合物与铜肽在上述功效上具有显著的协同增效作用；同时与对比例2的产品相比，采用双组分设计的洗发水功效更好，具有更显著的上述方面效果。It can be seen from the data in Table 5 that the two-component shampoo of the present invention has significant effects of stimulating scalp hair follicles, promoting hair growth and regeneration, and preventing hair loss, and the strontium compound and the copper peptide have significant synergistic effects on the above effects; at the same time, compared with the product of Comparative Example 2, the shampoo with a two-component design has better efficacy and more significant effects in the above aspects.

测试例5Test Example 5

头发顺滑度评价：Hair smoothness rating:

顺滑度由摩擦系数来决定，测试例4中的每名志愿者随机选取10根头发于载玻片排列固定后，从根部向毛发尖部用探测器梳理滑动，测定平均摩擦系数，分为三个等级(0.15以下、0.15-0.20、0.20以上)，记录各等级的人数。结果如表6所示。The smoothness is determined by the friction coefficient. In Test Example 4, each volunteer randomly selected 10 hairs and arranged them on a glass slide. The hairs were combed and slid from the root to the tip with a probe to measure the average friction coefficient. The friction coefficient was divided into three levels (less than 0.15, 0.15-0.20, and more than 0.20), and the number of people in each level was recorded. The results are shown in Table 6.

表6Table 6

由表6数据可知：志愿者在使用本发明所涉及的洗发水后，毛发的顺滑度有明显提高。且洗发水的组成配方显著影响其在毛发的顺滑度方面的效果。From the data in Table 6, it can be seen that after using the shampoo of the present invention, the smoothness of the hair of the volunteers was significantly improved, and the composition formula of the shampoo significantly affects its effect on the smoothness of the hair.

申请人声明，本发明通过上述实施例来说明本发明的一种具有头皮滋养功效的双组分洗发水及其制备方法。，但本发明并不局限于上述实施例，即不意味着本发明必须依赖上述实施例才能实施。所属技术领域的技术人员应该明了，对本发明的任何改进，对本发明产品各原料的等效替换及辅助成分的添加、具体方式的选择等，均落在本发明的保护范围和公开范围之内。The applicant declares that the present invention uses the above-mentioned embodiments to illustrate a two-component shampoo with scalp nourishing effect and a preparation method thereof. However, the present invention is not limited to the above-mentioned embodiments, that is, it does not mean that the present invention must rely on the above-mentioned embodiments to be implemented. Those skilled in the art should understand that any improvement of the present invention, equivalent replacement of various raw materials of the product of the present invention, addition of auxiliary components, selection of specific methods, etc., all fall within the protection scope and disclosure scope of the present invention.

以上详细描述了本发明的优选实施方式，但是，本发明并不限于上述实施方式中的具体细节，在本发明的技术构思范围内，可以对本发明的技术方案进行多种简单变型，这些简单变型均属于本发明的保护范围。The preferred embodiments of the present invention are described in detail above. However, the present invention is not limited to the specific details in the above embodiments. Within the technical concept of the present invention, a variety of simple modifications can be made to the technical solution of the present invention, and these simple modifications all belong to the protection scope of the present invention.

另外需要说明的是，在上述具体实施方式中所描述的各个具体技术特征，在不矛盾的情况下，可以通过任何合适的方式进行组合，为了避免不必要的重复，本发明对各种可能的组合方式不再另行说明。It should also be noted that the various specific technical features described in the above specific embodiments can be combined in any suitable manner without contradiction. In order to avoid unnecessary repetition, the present invention will not further describe various possible combinations.

Claims (19)

1. The bi-component shampoo with the scalp nourishing effect is characterized by comprising a first component and a second component which are prepared and packaged separately;

the first component comprises 15-30% of surfactant, 5-15% of foam booster, 1-10% of conditioner, 1-5% of thickener, 1-5% of lubricant, 0.1-0.5% of preservative, 0.05-0.5% of pH regulator and water by taking the mass of the bi-component shampoo with scalp nourishing effect as 100%; the second component comprises 1-5% of humectant, 1-5% of conditioner and 5-15% of water;

the conditioning agent in the second component comprises a strontium-containing compound and a copper peptide; the strontium-containing compound comprises any one or a combination of at least two of strontium chloride, strontium chloride hexahydrate, strontium hydroxide, strontium acetate, strontium citrate and strontium gluconate; the mass ratio of the copper peptide to the strontium-containing compound is 1 (10-50).

2. The dual component shampoo with scalp nourishing effect according to claim 1, wherein the conditioning agent in the first component comprises any one or a combination of at least two of allantoin, dendrobium candidum extract, glycerol cocoate, guar hydroxypropyl trimonium chloride, hydrolyzed silk protein, or panthenol.

3. The dual component shampoo with scalp nourishing effect according to claim 1, wherein the conditioning agent in the first component comprises a combination of allantoin, dendrobium candidum extract, glycerol cocoate, guar hydroxypropyl trimonium chloride, hydrolyzed silk protein, and panthenol.

4. The dual component shampoo with scalp nourishing effect according to claim 1, wherein the surfactant comprises any one or a combination of at least two of ammonium laureth sulfate, potassium cocoyl hydrolyzed oat protein, octyl/decyl glucoside, lauryl glucoside, sodium alpha-alkenyl sulfonate, sodium methyl cocoyl taurate, ricinoleic acid amide propyl trimethyl ammonium chloride, polyethylene glycol stearate, cetostearyl alcohol.

5. The dual component shampoo with scalp nourishing effect according to claim 1, wherein the foam booster comprises any one or a combination of at least two of cocamidopropyl betaine, alkyl alcohol amide, propylene glycol monolaurate, acrylic/VA copolymer.

6. The dual component shampoo with scalp nourishing effect according to claim 1, wherein the thickener comprises any one or a combination of at least two of polyquaternium-7, PEG-150 distearate, xanthan gum, guar gum, alginate, hydroxyethyl cellulose.

7. The dual component shampoo with scalp nourishing effect as claimed in claim 1, wherein the lubricant comprises silicone oil.

8. The dual component shampoo with scalp nourishing effect according to claim 1, wherein the moisturizer comprises any one or a combination of at least two of hyaluronic acid, sodium hyaluronate, propylene glycol, glycerol, panthenol.

9. The dual component shampoo with scalp nourishing effect as claimed in claim 8, wherein the hyaluronic acid is a combination of macromolecular hyaluronic acid, medium molecular hyaluronic acid and small molecular hyaluronic acid.

10. The dual component shampoo with scalp nourishing effect as claimed in claim 8, wherein the sodium hyaluronate is a combination of macromolecular sodium hyaluronate, medium molecular sodium hyaluronate and small molecular sodium hyaluronate.

11. A two-component shampoo with scalp nourishing effect according to claim 1 wherein said first component further comprises a fragrance and/or a toner.

12. A method for preparing a two-component shampoo with scalp nourishing effect according to any one of claims 1 to 11, characterized in that the preparation method comprises:

and respectively mixing the raw materials in the first component and the second component to prepare the first component and the second component.

13. The method for preparing a dual component shampoo with scalp nourishing effect according to claim 12, wherein the method for preparing the first component comprises:

(1) Mixing water with a surfactant, a foam booster and a part of conditioner to obtain a component A;

(2) Mixing the component A with a thickener, a lubricant and the rest of conditioner to obtain a component B;

(3) And mixing the component B with other residual raw materials to obtain a first component.

14. The method of claim 13, wherein the partial conditioner of step (1) comprises allantoin and dendrobium candidum extract.

15. The method for preparing a dual component shampoo with scalp nourishing effect according to claim 13, wherein the mixing in step (1) is performed under stirring at 75-90 ℃ for 15-30min at a stirring speed of 20-35 r/min.

16. The method for preparing a dual component shampoo with scalp nourishing effect according to claim 13, wherein the mixing in step (2) is performed under stirring at 40-55 ℃ for 15-30min and at a stirring speed of 15-30 r/min.

17. The method for preparing a dual component shampoo with scalp nourishing effect according to claim 13, wherein the mixing in step (3) is performed under stirring, the stirring is performed at 40-55 ℃ for 15-30min, and the stirring speed is 15-30 r/min.

18. The method of preparing a dual component shampoo with scalp nourishing effect as claimed in claim 13, wherein the pH of the first component is 5.5-6.5.

19. The method for preparing a two-component shampoo with scalp nourishing effect according to claim 13, wherein the method for preparing the second component comprises: stirring the humectant, the conditioner and water at 30-55deg.C for 10-40 min.